2 Revie w on Effects of Sport2assisted Treatment f or Chinese Patients of NIDDM
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1 :000677X(009) ( 9 ) 9 CHINA SPOR T SCIENCE Vol. 9,No. 9,780,009. Revie w on Effects of Sportassisted Treatment f or Chinese Patients of NIDDM Q IAO Yucheng :: :CN KI ( VIP) / RevMan4. Meta :7,,, Mata :, h ( ) ( P < 0. 05) : : Meta; ; ; ; Abstract :Purpose : Comprehensively evaluating the effect s of sportassisted treatment for Chi nese patient s of N IDDM. Methods : Retrieve online all the literature during 999 to 008 in CN KI Chinese Academic Periodical Net f ulltext database and Chinese Scientific and Techno logical Journals f ulltext database ( V IP), search for random and semirandom controlled trials that conform to inclusion criteria and evaluate their quality, and conduct Metaanalysis to the obtained related data utilizing RevMan4. statistical software. Result s : Include 7 original lit eratures, of which were evaluated highquality,and lowquality and find no allocation hid ing in all the research. Metaanalysis shows that compared to controlled set,exercise interven tion set have substantial differences in controlling fasting blood glucose,postprandial blood glu cose ( h), glycosylated hemoglobin and adjusting fasting insulin level,insulin sensitivity index and insulin resistance index,and reducing the risk factors of diabetes and cardiovascular disease ( body mass index, waist hip ratio, blood pressure and blood lipid). Conclusions : Although ac cording to report s by domestic journals, the effect s of sportassisted treatment for NIDDM can be taken as proof for effectiveness of sportassisted treatment, the authenticity will still be questioned because of the shortage of high quality clinical trial research. Key words : Metaanal ysis ; t reatment ef f ect ; N I DDM ; exercise intervention ; domestic patients : G : A, 0 Meta,. 7 ( ), CN KI ( VIP) (999 WHO ) : ; : :(9),,, Tel : ( 0357) 080, com : Shanxi Normal University,Linfen China.
2 : 3 ( ), () ; ( 7 ( ), ) Jadad [ ], 5,, 3 5 [9 ]. 5 h ( Tch TG HDLC LDLC). 6 Cochrane RevMan 4. Meta, ( P > ), Meta ;( P < ), Peto (OR),( WMD),95 % (). 6, ( 47, 03 ). 7 ( 3), (< 3) ( ) Table Basic Situations of the Researches (n) Jadad,,, : 73
3 009 ( 9 ) 9. 3 Meta ( 874,773 ) 0 ( = 97. 5, P < ),, ( ) : SMD = ,95 % CI( , ), P < , Meta Table Metaanalysis of Sportassisted Treatment s Effects on Controlling NIDDM Patients Fasting Blood Glucose,,, () (n) X SD(mmol/ L) (n) X SD(mmol/ L) ( %) : = 97. 5,df = 9, P < , :Z = 4., P < SMD() ( -., ) ( -. 0, ) -. ( -. 9, ) -. 6 ( -., - 0. ) ( ,0. ) -. 9 ( -., -. 8) - 0. ( , - 0. ) ( -. 76, ) ( -. 3, ) ( - 0.,0. 4) - 0. ( -. 53, ) -. ( -. 70, ) ( , - 0. ) ( -. 7,0. 3) ( -., ) ( ,0. 0) ( , - 0. ) ( -. 00, - 0. ) - 0. ( ,0. 07) -. ( -. 94, -. 4) ( , ). 3.. h 4 h 7 (574,538 ) 4 ( = 7., P < ),, ( 3) : SMD = , 95 % CI ( , ), P < , h (668, ) 6 ( = 85. 4, P < ), ( 4) : SMD = , 95 % CI ( -. 05, ), P < , ,, 0 ( = 4. 99, P < ),, ( 5 ) : SMD = ,95 % CI( , - 0. ), P < ,,. 3.. ( = , P < ),, ( 6) : SMD =. 63,95 % CI (. 04,. ), P < , 74
4 : 3 h Meta Table 3 Metaanalysis of Sportassisted Treatment s Effect on Controlling NIDDM Patients Postprandial Blood Glucose ( h),, () (n) X SD(mmol/ L) (n) X SD(mmol/ L) ( %) : = 7.,df = 3, P < ; :Z = 3. 4, P < SMD() ( -. 39, -. ) -. 3 ( -. 88, ) ( -. 0, ) ( -. 7, ) ( -. 7, - 0. ) ( -. 05,0. 00) ( -. 0, ) ( , - 0. ) ( -., ) (0. 96,0. 0) ( ,0. 5) ( -., ) ( , ) ( , -. 77) ( , ) 4 Meta Table 4 Metaanalysis of Sportassisted Treatment s Effect on Controlling NIDDM Patients Glycosylated Hemoglobin,,, () (n) X SD( %) (n) X SD( %) ( %) : : = 85. 4,df = 5, P < , :Z = 4. 97, P < SMD() ( -. 54, - 0. ) ( -., ) -. 6 ( , -. 69) ( , -. 4) ( -. 5, ) ( -. 86, -. 05) -. 9 ( -. 70, ) ( ,0. 0) - 0. ( ,0. ) -. ( -. 7, ) ( -. 49, ) ( -., - 0. ) ( -. 93, ) ( - 0., ) - 0. ( ,0. 0) ( -. 06, ) ( -. 05, ) 5 Meta Table 5 Metaanalysis of Sportassisted Treatment s Effect on Adjusting NIDDM Patients Fasting Serum Insulin Level,, () (n) X SD(mU/ L) (n) X SD(mU/ L) ( %) : : = 4. 99,df = 9, P < , :Z = 8. 89, P < SMD() ( , ) ( - 0.,0. 74). 5 (0. 89,. 5) ( -. 73, ) ( -., -. 7) - 0. ( - 0.,0. 34) -. ( -. 9, -. 87) ( ,0. ) ( - 0.,0. ) - 0. ( ,0. 6) ( , - 0. )
5 009 ( 9 ) 9 6 Meta Table 6 Metaanalysis of Sportassisted Treatment s Effect on Adjusting NIDDM Patients Insulin Sensitivity Index () (n) X SD (n) X SD ( %) SMD() 0. 6 ( ,. 9) 4. 8 (3. 6,6. 00). 63 (. 04,. ) : : = ,df =, P < , :Z = 5. 64, P < ( = 4. 69, P < ),, ( 7) : SMD = -. 65,95 % CI( -. 97, -. ), P < , 7 Meta Table 7 Metaanalysis of Sportassisted Treatment s Effect on Decreasing NIDDM Patients Insulin Resistance Index () (n) X SD (n) X SD ( %) SMD() -. 6 ( - 3., -. ) ( -. 38, ) ( -. 97, -. ) : : = 4. 69,df =, P < , :Z = 0. 06, P < [4 ],, WMD = - 0.,95 % CI( -., ), P < , ;WMD = -. 5,95 % CI( -. 09, ), P < , [8 ],4 h WMD = , 95 % CI ( , ), P < , ; WMD = -. 0, 95 % CI( -. 04, 7. 64), P = 0. 66, WMD = , 95 % CI( ,0. 53), P = 0. 07, ( 0,54 ) 3 ( = 3., P = 0. 00), ( 8) : SMD = - 0.,95 % CI ( , ), P < , (65,6 ) 3 ( = 5. 0, P = ), ( 9 ) : SMD = - 0.,95 % CI( , ), P < , (, 95 ) 7 ( = 5. 77, P < ),, ( 0) :SMD = ,95 % CI( , - 0. ), P < ; SMD = , 95 % CI ( , ), P < , ( Tch ) :5 ( Tch ) 9 (,537 ) 5 ( =
6 : 3. 99, P < ),, ( ) : SMD = -. 4, 95 % CI ( -. 90, - 0. ), P < , Tch 8 Meta Table 8 Metaanalysis of Sportassisted Treatment s Effect on Decreasing NIDDM Patients Body Mass Index (n) X SD(kg/ m ) (n) X SD(kg/ m ) ( %) , , () : : = 3.,df =, P = 0. 00, :Z = 9., P < SMD() ( , -. ) ( -. 0, - 0. ) ( -. 88, - 0. ) ( ,0. 0) ( ,0. 06) - 0. ( ,0. ) ( - 0., ) - 0. ( , ) ( ,0. ) ( ,0. 0) ( ,0. 0) ( -. 3, ) ( -., ) - 0. ( , ) 9 Meta Table 9 Metaanalysis of Sportassisted Treatment s Effect on Controlling NIDDM Patients Waist Hip Ratio () (n) X SD (n) X SD ( %) : = 5. 0,df =, P = , :Z = 5. 7, P < SMD() ( -. 96, -. ) ( , - 0. ) ( ,0. 09) - 0. ( , ) 0 Meta Table 0 Metaanalysis of Sportassisted Treatment s Effect on Adjusting NIDDM Patients Blood Pressure () (n) X SD(mm Hg) (n) X SD(mm Hg) ( %) : =. 79,df = 6, P < , :Z = 8. 48, P < () SMD() ( , ) ( -. 47, ) ( -., - 0. ) ( -. 34, ) ( - 0., ) ( ,0. 07) ( -. 45, ) ( , - 0. ) ( , ) ( , ) ( -., ) ( -. 44, - 0. ) ( , - 0. ) 0. 6 ( - 0.,0. ) ( -. 7, ) ( , ) : = 08. 3,df = 6, P < ; :Z = 5., P < () ( - 0., ) : = 5. 77,df = 3, P < , :Z = 9. 9, P <
7 009 ( 9 ) 9 Tch Meta Table Metaanalysis of Sportassisted Treatment s Influence on NIDDM Patients Serum Tch,, () (n) X SD(mmol/ L) (n) X SD(mmol/ L) ( %) : = 3. 99,df = 4, P < , :Z = 9. 7, P < SMD() ( -.,0. 04) ( -. 9, ) ( ,0. ) ( -. 77, ) ( -. 44, - 0. ) ( -. 3, - 0. ) -. 4 ( -. 03, ) -. 9 ( -. 7, ) ( - 0.,0. ) ( ,0. 0) - 0. ( ,0. ) ( - 3., -. 09) (0. 0,. 05) ( ,0. 0) -. 4 ( -. 90, - 0. ) - 0. ( , ) ( TG) :7 ( TG) 36 (69,635 ) 7 ( = 8. 49, P < ),, ( ) : SMD = , 95 % CI ( , ), P < , TG TGMeta Table Metaanalysis of Sportassisted Treatment s Influence on NIDDM Patients Serum TG,, () (n) X SD(mmol/ L) (n) X SD(mmol/ L) ( %) : = 8. 49,df = 6, P < , :Z = 5. 54, P < SMD() - 0. ( ,0. ) - 3. ( , -. 9) - 0. ( ,0. ) ( ,0. 0) -. 5 ( -. 54, ) - 0. ( ,0. 65) ( -. 6, ) ( - 0.,0. 44) ( -. 5, ) ( ,0. 7) 0. 3 ( ,0. 4) ( ,0. 35) ( , ) - 0. ( ,0. 03) 0. (0. 05,. 08) ( ,0. 0) ( -. 50, ) ( , ) 3 ( HDLC) :3 ( HDLC) 083 (9,54 ) 3 ( = , P = ),, ( 3) : SMD = 0., 95 % CI(0.,0. 46), P < , HDLC 78
8 : 3 HDLC Meta Table 3 Metaanalysis of Sportassisted Treatment s Influence on NIDDM Patients blood HDLC,, () (n) X SD(mmol/ L) (n) X SD(mmol/ L) ( %) : = ,df =, P = ; : Z = 5. 3, P < SMD(). 5 (0. 76,. 6) 0. ( ,0. 66) (0. 3,0. 86) 0. ( ,0. 9) 0. 6 ( ,0. 7) (0. 7,. 6) 0. 5 ( ,0. 43) 0. ( - 0.,0. 76) ( - 0.,0. ) ( - 0.,0. ) ( - 0.,0. ) 0. 8 (0. 37,. 7). 7 (0. 5,. 8) 0. (0.,0. 46) 3 (LDLC) :9 (LDLC) 790 (397, 393 ) 9 ( =. 77, P < ),, ( 4) : SMD = , 95 % CI( - 0., ), P < , LDLC 4 LDLC Meta Table 4 Metaanalysis of Sportassisted Treatment s Influence on NIDDM Patients Blood LDLC, () (n) X SD(mmol/ L) (n) X SD(mmol/ L) ( %) : =. 77,df = 8, P < ; : Z = 5. 70, P < SMD() ( -.,0. 5) ( -. 0, - 0. ) - 0. ( ,0. 5) ( -. 03, ) ( -. 39, - 0. ) ( -., ) ( - 0.,0. ) ( -. 0, ) 0. ( - 0.,0. 8) ( - 0., ). 4 ( ), Figure Publication bias Evaluation Funnel Plot 3 3. Meta Meta( Metaanalysis),, 3. Meta, 79
9 009 ( 9 ) 9 Jaadd 3,, 9. %,,,, Meta ; ;, 4 ; 3. 3 Meta h,, ( ) : [ ]. [J ].,005,0 (7 ) :5. [ ],. [J ].,004,0 (3) :67. [3 ]. [J ].,005, 0 (4 ) :96. [4],. [J ].,003,6() :663. [5 ]. 80 [J ].,007,4 (0) :35. [ 6 ],,. [J ]., 005,9 (39) :4. [ 7 ],,. [J ].,003, (9) :6776. [8 ],. ( ) [J ].,004,6 () :46. [9],. [J ].,006,(6) :557. [ 0 ]. [J ].,003,0 (6) :79. [ ],. [J ].,004,9 (5) : [ ],,. [J ].,00,0 (4) :34. [ 3 ]. [J ].,005,3 (7) :89. [ 4 ]. [J ].,003,7 (9) :35. [ 5 ],. [J ].,004, (6) : [ 6 ]. [J ].,008,5 (7) :555. [ 7 ]. 3 [J ].,004, (03) :3. [ ],. [J ].,006,9 () :9797. [ 9 ]. [J ].,008,9 (ll) :4344. [ 0 ]. [J ].,006,6 (6 ) :3. [ ],,. [J ].,00,9 (6) :357. [],. [J ].,005,9() :7. [ ]. 05 [J ].,00, (3) :4. [ 4 ],,. [J ].,006, (6) : [ ]. [J ].,00, (3) :9. [ 6 ]. [J ]., 008,0 (l) :8. [ 7 ]. [J ]. (),006, () :3. [ ] J ADAD AR, MOORE A, CARROLL D, et al. Assessing t he quality of reports of randomized clinical trials : Is blinding nec essary [J ]. Control Clinic Trials,996,7 :. [ 9 ] MO HER D,P HAM B,J ON ES A, et al. Doesquality of report s of randomized trials affects estimates of intervention efficacy reported in Meta analysis[j ]. Lancet,9,35 :9 63.
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