Breast Disease Centres
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1 Breast Disease Centres The Future M.Marty. 02/2012 1
2 Evolution de la Mortalité par Cancer du sein dans le monde
3 Taux Standardisé de Mortalité par Cancer du Sein en France ( )
4 A HUGE IMPROVEMENT IS MANDATORY: BREAST DISEASE CENTRES M.Marty. 02/2012 4
5 Breast Disease Centres Certified specialized centres in charge of High risk families and patients Benign but evolutive breast diseases Breast Cancer Diagnosis, Management, Rehabilitation Involving as part of the unit (the Director may be any of these specialist) Imaging Surgery and reconstructive surgery Radiotherapy Systemic therapy Side-effects Psychological support Management of quality With an established expertise in Training Research (translational, clinical) M.Marty. 02/2012 5
6 Requirements for certification (1) quality management system At the level of each specialty involved (Imaging, pathology, repositories, surgery, radiotherapy, systemic therapy, nurses, psychologists) according to the recommandations of national and international societies And of interdisciplinarity (timelines, reporting, Adverse effects, multidisciplinary meetings and reports) If possible with external assessment Improved by local breast disease hospital registries linked to those of other Breast Clinics The net number of patients managed by each specialist is a key to Quality : the number advised by Eusoma (150 newly diagnosed cases) may be too low in view of the increasing complexity of diagnostic and therapeutic approaches M.Marty. 02/2012 6
7 The Quality Management System (2) Procedures in all areas of activity as well as Multidisciplinary management and pats information written, available (Website), and collectively amended Database of patients and procedures including markers of quality ( data managers). Ideally they can provide electronic aid to decision-making All Muldidisciplinary meetings registered with the members, patients discussed and impact on management.% of pts discussed may vary If they fit with the unit procedures and if the database provides automatic warning, registration without discussion possible >90% of all other cases should be discussed All corrective measures, EEQ, audit must be registered, collectively discussed and disseminated M.Marty. 02/2012 7
8 Database and Quality Management Breast Disease Centres Registries vs Population based Registries A slight majority (53%) of the cancer site and treatment combinations showed kappa statistics > or = 0.60 and percent agreements, sensitivities, and predictive values positive :distribution of surgery, radiotherapy, systemic therapies site-specific factors and derived variables were inconsistent importance of Local (networked) data registries J.Registry.Manag.2011, 38,2 M.Marty. 02/2012 8
9 New Technologies Argue for Increased Size of Breast Disease Centres Imaging: 3D digital mamography, Constrast enhanced US, NMR with breast antenna, spectrography, stereotactic biopsies (stereotactic,, mammography, NMR guided) Pathology: automatized IHC and recognition system, transfert of images Nuclear medecine (PET Scan, scintigraphy, tomoscintigraphy) Freezing facilities and molecular biology (Q-RTPCR, GEP, NGS, analysis of circulating DNA, genetics) Surgery (BCS, immediate reconstruction,plastic partial reconstruction, SN biopsies and molecular analysis) Radiotherapy: IOR, conformational, partial, accelerated All systemic treatments available and mastered M.Marty. 02/2012 9
10 New technologies=new Jobs Ingeneers Technician Biologists, biomathematics Quality managers Data managers M.Marty. 02/
11 NG-BDC (Next Generation Breast Disease Centres) Full equipment and dedicated non-medics professional Local comprehensive database Networking with other BDC Integrated Management of Quality No lags in prespecified timelines Reporting tools (and team) Strong involvement in clinical and translational research M.Marty. 02/
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