CURRICULUM VITAE Karen Barbara Domino, M.D., M.P.H

Transcription

1 CURRICULUM VITAE Karen Barbara Domino, M.D., M.P.H Education: 1973 Vassar College, Poughkeepsie, New York B.A. Psychology w/honors 1974 University of New Mexico, Albuquerque, New Mexico M.A. Psychology 1978 University of Michigan, Ann Arbor, Michigan M.D. With honors 1998 University of Washington, Seattle, Washington M.P.H. Health Services Postgraduate Training: University of Pennsylvania, Philadelphia, Pennsylvania Internship Surgery University of Pennsylvania, Philadelphia, Pennsylvania Residency Anesthesia University of Pennsylvania, Philadelphia, Pennsylvania Fellowship Cardiac Anesthesia University of Pennsylvania, Philadelphia, Pennsylvania Fellowship Neuroanesthesia Robert Wood Johnson Foundation (RWJF) Fellowship Health Policy Fellowship, Institute of Medicine, Washington, DC American Political Science Association (APSA) Fellowship Faculty Positions Held: Congressional Fellowship, Washington, DC Acting Assistant Professor of Anesthesia, University of Pennsylvania, Philadelphia, Pennsylvania Assistant Professor of Anesthesiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania Assistant Professor of Anesthesiology, University of Washington School of Medicine, Seattle, Washington Associate Professor of Anesthesiology, University of Washington School of Medicine, Seattle, Washington Adjunct Associate Professor of Neurological Surgery, University of Washington School of Medicine, Seattle, Washington 1998-present Professor of Anesthesiology (& Pain Medicine in 2008) Adjunct Professor of Neurological Surgery, University of Washington School of Medicine, Seattle, Washington Hospital Staff Appointments: Deborah Heart and Lung Center, Browns Mills, New Jersey Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania Presbyterian-University Hospital, Pittsburgh, Pennsylvania 1986-present Harborview Medical Center and University of Washington Medical Center, Seattle, Washington Hospital and Departmental Administrative Positions: Director, Neurosurgical Anesthesia, Department of Anesthesiology, University of Pittsburgh Director of Continuous Quality Improvement, Department of Anesthesiology, Harborview Medical Center, Seattle Designed and implemented CQI system for department Chair, Medical Staff Committee for Continuous Quality Improvement, Harborview Medical Center. This committee was responsible for all of the CQI activities from all departments within the hospital. Reported to hospital Board of Directors. Resigned for sabbatical leave.

2 Curriculum Vitae Karen B. Domino, M.D., M.P.H. Page 2 Hospital and Departmental Administrative Positions (cont d): Director of Continuous Quality Improvement, Department of Anesthesiology, Harborview Medical Center, Seattle Designed and implemented new CQI process, teaching tools, database, resident/staff CQI conference, and presentations to operating room RNs. Formed a multidisciplinary group of operating room nurses (Perioperative Patient Safety Committee), preop and recovery nurses, surgeons, anesthesiologists, and hospital continuous quality improvement personnel to work together to resolve cross-disciplinary system problems that impair perioperative patient safety. Focus included impact of RN/tech/physician team interactions, perioperative system safety issues, preoperative assessments and other factors implicated in case turnaround, patient satisfaction, and anesthesia preop evaluation Associate Chief of Anesthesia and Technological Services, University of Washington Medical Center (UWMC), Seattle Position involved management of physician, nurse anesthesia, and anesthesia technician personnel, and trainees (medical students, interns, residents) at UWMC. Activities included strategic planning of staffing requirements, recruitment of personnel, scheduling, trouble shooting, conflict resolution, and personnel management in 30 anesthetizing locations; team-based management of OR, preoperative, and post-anesthesia care areas and non-or anesthesia services; management of anesthesia technicians and redesign of services to include tech manager, development of technician training programs in conjunction with North Seattle Community College, and certification of technicians as state health care assistants. Position also involved oversight of risk management for anesthesiology at UWMC, clinical guidelines and protocols, procedures and policies, emergency check-lists, and continuous quality improvement activities, Also, OR efficiency, strategic planning, and accreditation process support, and budget projections. Duties also included Division directorship of neurosurgical and spine anesthesia in Vacated position for in Washington DC Vice Chair and Director of Research, Department of Anesthesiology, University of Washington 2007-current Vice Chair for Clinical Research, Department of Anesthesiology & Pain Medicine, University of Washington Position involves mentorship of residents, fellows, and faculty in clinical and outcome research; review of all departmental IRB applications and seed grant funds; compliance for University requirements on human subjects research; strategic planning for academic and research affairs; budget development; space allocation; chair of ad hoc committees for endowed chair positions, academic affairs and residency selection committees for research emphasis in training program; mentorship of residents, fellows, junior faculty; director of resident research track, curriculum design; mentorship of Bonica scholars; designing/planning conferences to highlight Departmental scholarship (Academic Evening and Fink conferences); development and supervision of a clinical research core with a clinical coordinator, regulatory specialists, statistical support, IT and administrative support staff; and development of perioperative outcome database as part of a multi-institutional effort (MPOG). Planning of yearly Departmental Retreats, including a retreat on Quality and Patient Safety, in Provides oversight of Departmental CQI activities. Vacated position during l leave Robert Wood Johnson Health Policy Fellowship, Institute of Medicine, Washington, DC The health policy fellowship involved a residential experience in Washington DC, followed by continued health policy training, including development of a health policy curriculum for health science students. During the 4 month orientation, fellows met with directors at the Institute of Medicine, key executive branch officials responsible for health policy and programs (e.g. CDC, FDA, DOD, many branches of HHS, GAO, CRS, CBO), members of Congress and their staff, leaders of health and health policy interest groups, leaders of think tanks, health economists, and many different stakeholder groups. The breadth of health policy curriculum was broad and included health economics, federal budget process, a wide variety of federal health policy issues including health information technology, Medicare reform, Affordable Care Act, Medicaid Expansion, drug safety and regulation, public health concerns, healthcare workforce changes. The fellows also underwent leadership and media training. The fellows joined the American Political Science Association

3 Curriculum Vitae Karen B. Domino, M.D., M.P.H. Page 3 Congressional Fellowship Program to expand their knowledge and awareness of Congress and the political process, comparison with the Canadian government and health care system. January-August 2103: Health Subcommittee of the House Ways and Means Committee, which has jurisdiction over federal health care spending. I worked as a legislative assistant with committee staff and congressmen on a variety of topics: Medicare benefit reform, physician payment reform, quality and performance measurements, alternative care delivery systems and payment models (bundles, ACO), primary care initiatives, hospital concerns including readmission policy, DSH policy, and RACs, post-acute care reform, Medicare drug benefit reform, federal budget, solvency of the Medicare program, Medicare redesign, implementation of the Affordable Care Act with expansion of Medicaid, graduate medical education funding, health care workforce for the future, fraud and abuse, and have also met with CMS, lobbyists, constituent groups, and beneficiaries. Fall 2013: American Association of Medical Colleges: Health Care Affairs Division: Applied health policy knowledge to Academic medicine, including health care system assessments for readiness for transformation to alternative payment models and an educational program to improve physician knowledge of health care costs and reduce waste in the health care system. Administrative Training: MPH degree in Health Services-many classes with MHA program 2005 American College of Physician Executives Physicians in Management: Finance, Marketing, Healthcare, Management Skills, Influence, Negotiation UW Leadership Scholars-selected by School of Medicine for leadership development. Specific focus on Value in Healthcare and Protecting Our Academic Mission. Honors: 1973 Phi Beta Kappa 1973 Undergraduate Thesis in Psychology - Awarded Academic Distinction 1978 Alpha Omega Alpha 1982 First prize, New Investigator's Research Contest, New York Postgraduate Assembly in Anesthesiology 1984 The Dr. Leroy Harris Award for Excellence in Teaching, Department of Anesthesia, University of Pittsburgh 1990 B.B. Sankey Anesthesia Advancement Award 1990 Clinical Investigator Award, National Heart, Lung, and Blood Institute Who s Who in the West 1997-present Who s Who in Medicine and Health Care 2002-present Who s Who in America 2006-present Who s Who in the World 2007 John J. Bonica Award for Faculty Mentoring, University of Washington Department of Anesthesiology rd Emery A. Rovenstine Memorial Lecture, American Society of Anesthesiologists Board Certification: 1983 Diplomat, American Board of Anesthesiology 2000 Recertification, American Board of Anesthesiology 2009 Recertification, American Board of Anesthesiology License to Practice: Pennsylvania New Jersey 1985-present Washington

4 Curriculum Vitae Karen B. Domino, M.D., M.P.H. Page 4 Organizations: 1979-present American Society of Anesthesiologists (ASA) 1979-present International Anesthesia Research Society (IARS) Society of Cardiovascular Anesthesiologists 1982-present 1984-present Society for Neuroscience in Anesthesia and Critical Care (SNACC) American Medical Association American Heart Association, Cardiopulmonary Council 1991-present Association of University Anesthesiologists (elected membership) Teaching Responsibilities University Courses: Lectures and clinical instructor: University of Washington Anesthesiology residency training program Resident Mentorship/Academic Advisor to 2-4 residents/year since 1990 (not listed on CV) Mentorship (informal mentorship around US and internationallly not listed): Laboratory: 1.., , Pediatric Critical Care Fellow , undergraduate student 3.., , visiting scientist from Sweden , undergraduate student , Pediatric Anesthesia and Critical Care Fellow , visiting scientist from Sweden , visiting scientist from Korea , visiting scientist from Taiwan, Ph.D. candidate Health Services Research: 1.., , Post-Doctoral Fellow, Environmental Health: Cause-specific mortality risks of anesthesiologists compared to general internists. 2.., , Graduate student, Epidemiology: Cause-specific mortality risks of anesthesiologists compared to general internists present, Associate Professor, Anesthesiology: ASA Closed Claims Project/Perioperative Visual Loss Registry. 4.., 2001-present, Professor, Anesthesiology: Complications of chronic pain management: closed claims analysis. 5.., , Acting Assistant Professor, Anesthesiology: Awareness during anesthesia and central line complications. 6.., 2002-present, Associate Professor, Anesthesiology: Closed claims difficult airway. 7.., , Acting Assistant Professor, Anesthesiology: Preop assessment and continuous quality improvement present, Associate Professor, Anesthesiology: Closed claims analysis, POCA Registry. 9.., , Resident, Anesthesiology: Burns and soft tissue injuries: closed claims analysis. 10.., , Resident, Anesthesiology: Recrudescence after malignant hyperthermia reactions, MHAUS database study.

5 Curriculum Vitae Karen B. Domino, M.D., M.P.H. Page 5 Mentorship; Health Services Research (cont d): present, Associate Professor, Anesthesiology: Closed claims analysis of OB anesthesia claims. 12.., , Associate Professor, Anesthesiology: Trends in pediatric anesthesia: closed claims analysis. 13., 2005-present, Associate Professor, Anesthesiology: Awareness during anesthesia and closed claims analysis , Resident, Anesthesiology: Closed claims analysis peripheral catheters, chronic pain management , Resident, Anesthesiology: Liability associated with acute pain management. 16., 2007, medical student, FAER Anesthesia Research Fellowship: A closed claims analysis of upper extremity surgery claims. 17.., 2006-present, Associate Professor, Anesthesiology: Closed claims, NORA, sedation practices , Resident, Anesthesiology: Closed claims; medication errors , Resident, Anesthesiology: Closed claims; aspiration , Resident Research Track, Anesthesiology: Closed claims; cautery fires; burns from warming devices; injuries from gas delivery equipment. 21.., , Research Fellow, Anesthesiology: Shared decision making, informed consent; Closed Claims; central venous catheter complications. 22.., 2012, Resident, Anesthesiology: Closed claims; OB hemorrhage , Resident, Anesthesiology: Closed claims; esophageal injuries present, Medical student, FAER Anesthesia Research Fellowship: Closed claims; injury and liability in neurosurgical anesthesia , Resident, Anesthesiology: Quality Improvement Project , Acting Assistant Professor, Anesthesiology: Closed claims; pain medicine liability. 27., 2014, Medical student: Closed claims; airway injuries Editorial Responsibilities: Consultant for Journal of Applied Physiology 1991 Consultant for Journal of Critical Care 1991-present Consultant for Anesthesiology 1992 Consultant for Lung 1993-present Consultant for Anesthesia and Analgesia 1994 Consultant for Respiration Physiology Consultant for Journal of Clinical Investigation 1996-present Consultant for Critical Care Medicine Editorial Board, American Journal of Anesthesiology Editorial Board, Journal of Cardiothoracic and Vascular Anesthesia Editorial Board, Journal of Neurosurgical Anesthesiology 2009-present Consultant for JAMA 2010-present Consultant for Lancet

6 Curriculum Vitae Karen B. Domino, M.D., M.P.H. Page 6 Editorial Responsibilities (cont d): 2012 Consultant for British Journal of Anaesthesia 2012 Consultant for British Medical Journal 2013 Consultant for New England Journal of Medicine Special National Responsibilities: American Society of Anesthesiologists Member, Committee on Experimental Circulation Member, Committee on Respiration Chair, Subcommittee on Respiration Member, Committee on Scientific Papers 1997-present Member, Task Force on Trace Anesthetic Gases Member, Committee on Professional Liability Member, Committee on Occupational Health of Operating Room Personnel Chair, Committee on Professional Liability Patient safety activities, member surveys, medical liability issues, informed consent, survey of malpractice premiums and trends, patient safety education, and interaction with the press and members. Committee developed an educational program on medical liability and anesthesia shared decision making modules Member, Ad Hoc Committee on Expert Witness Testimony Member, Subcommittee on Clinical Neurosciences Member, Task Force on CME Strategic Planning Member, Ad Hoc Committee on Spinal Manipulation Member, ASA Task Force on Perioperative Blindness Developed practice advisory for perioperative visual loss associated with spine surgery Member, ASA Task Force on Brain Function Monitoring for Awareness Developed practice advisory for brain function monitoring to prevent intraoperative awareness Member, Educational Track Subcommittee on Neuro Anesthesia for Annual Meeting Designed scientific program for the Annual Meeting Chair, Educational Track Subcommittee on Neuro Anesthesia for Annual Meeting Designed curriculum in neuroscience and neuroanesthesia for ASA annual meeting present Member, Committee on Annual Meeting Oversight Member, ASA Task Force on Central Venous Access Developed practice guideline for insertion and care of central venous catheters Member, ASA Task Force on Perioperative Blindness Developed practice advisory updated report present Member, Executive Committee of Annual Meeting-ASA Leadership position overseeing planning and administration of the ASA Annual Meeting, with 15,000 attendees nd Vice Chair, Annual Meeting st Vice Chair, Annual Meeting Chair, Annual Meeting (overseeing a redesign of the entire Annual meeting)

7 Curriculum Vitae Karen B. Domino, M.D., M.P.H. Page 7 Society for Neuroscience in Anesthesia and Critical Care (SNACC) 1992 SNACC Bibliography Contributor (neurogenic pulmonary edema, cerebral hemorrhage, and cerebrovascular disorders) SNACC Annual Meeting Abstract Reviewer 1994 SNACC Bibliography Contributor 1996 SNACC Annual Meeting Abstract Reviewer 1996 SNACC Bibliography Contributor 1998 SNACC Bibliography Contributor 2000 Editor, Selected References in Neurosurgical Anesthesia and Critical Care 2000 Edited 2000 update of SNACC Bibliography. Involved coordination and production of contributions by 38 national and international anesthesiologists on 40 different topics, procurement of funds for publication, and posting on SNACC website Editor, Selected References in Neurosurgical Anesthesia and Critical Care 2002 Edited 2002 update (similar to 2000) of SNACC Bibliography for website posting, with S. Soriano, assistant editor Secretary-Treasurer, Board of Directors Activities involved newsletter production, secretarial activities, budget accounting, and society strategic planning Vice President for Education and Scientific Affairs, Board of Directors Activities involved annual meeting planning and execution, formation of scientific affairs committee and development of society-wide research program, educational activities, society strategic planning, and recruitment of industrial financial support President-Elect, Board of Directors Responsible for annual meeting planning, organization, recruitment of financial support from industrial sponsors President, Board of Directors Responsible for direction of society and recruitment of financial support from industrial sponsors Immediate Past President, Board of Directors Chair, SNACC Teacher of the Year Committee Chair, Committee on Surveys American Board of Anesthesiology Question Writer, ABA/ASA In-Training Examination 1995-present Associate Examiner, Senior Examiner since Member, Oral Examination Test Writing Committee 2011-present Member, ABA Review Panel Formal review process for applicants denied entrance into review process, candidates whose request for an ABA examination under non-standard conditions was denied, or diplomats who have had their ABA certification revoked. Association of University Anesthesiologists (elected membership) Member, Scientific Advisory Board Councilor-at-large, Board of Directors

8 Curriculum Vitae Karen B. Domino, M.D., M.P.H. Page 8 Miscellaneous 1994 Member, Special Review Committee, NIGMS, Program Project Grant 1997 Member, Special Review Committee, NIGMS 2007-present Consultant, Anesthesiology and Respiratory Therapy Devices Panel of the Medical Devices Advisory Committee, Center for Devices and Radiological Health, Food & Drug Administration 2011 Consultant, Department of Defense Grant Review Committee Consultant, Canadian Government Medical Grant Review Committee Special Local (University of Washington) Responsibilities: Member, Admissions Committee, University of Washington School of Medicine Dean's Committee Representative, Seattle Veterans Affairs Medical Center, Research and Development Committee Member, Chair of Department of Anesthesiology Search Committee Director of Continuous Quality Improvement, Department of Anesthesiology, Harborview Medical Center 1993 Member, Women in Medical Faculty Project Group Chair, Medical Staff Committee for Continuous Quality Improvement, Harborview Medical Center Member, Harborview Medical Center Hospital Quality Assessment Committee Dean s Committee Representative, Puget Sound Veterans Affairs Medical Center, Research and Development Committee Director of Continuous Quality Improvement, Department of Anesthesiology, Harborview Medical Center Member, Search Committee for Chair of Otorhinolaryngology Member, Faculty Advisory Committee Recruitment and Retention Member, Award for Outstanding Faculty Mentorship Committee, School of Medicine Member, Council on Appointments and Promotions, School of Medicine (elected position) Special Departmental Responsibilities: Coordinator, Anesthesiology Resident Lecture Series, University of Pittsburgh Member, Anesthesiology Resident Selection Committee, University of Pittsburgh 1988 Member, Financial Review Committee 1990 Member, Ad Hoc Committee on Part-time Employment Coordinator, Mock Oral Exams for Residents Member, Anesthesia Research Committee 1992 Member, Ad Hoc Committee on Pain Training During the Anesthesia Residency Coordinator, Visiting Professor Series 1998-present Clinical Director, Health Services Research 2002 Member, Working Group on Communication and PhD Faculty Integration. Departmental Research Review present Member, Anesthesiology Resident Selection Committee Chair, Ad Hoc Committee for Vice Chair for Research Review

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10 Curriculum Vitae Karen B. Domino, M.D., M.P.H. Page 10 investigation of closed anesthesia malpractice claims designed to identify major areas of loss, patterns of injury, and strategies for prevention; 2) The Postoperative Visual Loss Registry, which investigates the mechanism of perioperative ischemic optic neuropathy, a rare but devastating complication of nonophthalmic surgery using a case-control study design; and 3) The Anesthesia Awareness Registry, which investigates patient experiences and perspectives after intraoperative awareness. Oversight of a large group of US reviewers, participating insurance companies, and research staff. International mentorship to establish closed claims-related projects in the U.K., Colombia, South Africa, and Brazil NINDS Drug Interactions at the Human Blood Brain Barrier, Co-investigator (PI (b)(6), PhD). PET scanning of human blood brain barrier in normal subjects and patients with Alzheimer s disease AHRQ 1R21 HS Shared Decision-Making in Surgery to Improve Patient Safety and Reduce Liability. K.B. Domino, Principal Investigator, 9/01/10-8/31/12, total direct (b) (4). This study will test implementation and evaluation of a surgical and anesthesia shared decisionmaking process in orthopedic surgery to provide valuable information regarding the costs and effectiveness of shared decision-making tools in improving patient safety and reducing liability. The results will be useful to health systems in making decisions regarding implementation of shared decision-making in surgical care Robert Wood Johnson Foundation Health Policy Fellow, 9/1/2012-8/31/2014, direct costs (b) (4). Participation in the health and health care policy process at the federal level to provide leadership in improving health, health care, and use of health policy at the national, state, and local level present Anesthesia Quality Institute Closed Claims Project, K.B. Domino, Principal Investigator, (b) (4) for 2013; (b) (4) for Current areas of investigation include: 1) Closed Claims Project, an indepth investigation of closed anesthesia malpractice claims designed to identify major areas of loss, patterns of injury, and strategies for prevention; 2) The Postoperative Visual Loss Registry, which investigates the mechanism of perioperative ischemic optic neuropathy, a rare but devastating complication of non-ophthalmic surgery using a case-control study design; 3) The Anesthesia Awareness Registry, which investigates patient experiences and perspectives after intraoperative awareness, 4) Obstructive Sleep Apnea Registry, which investigates causes of adverse perioperative outcomes in patients with obstructive sleep apnea, and 5) Neurological Injury after Non-supine Shoulder Surgery Registry, which investigates causes of adverse neurological outcomes in patients undergoing sitting shoulder surgery. Project involves planning of areas of investigation, oversight of data collection by more than 50 reviewer volunteers, more than 20 malpractice insurance companies, and research staff and database at the University of Washington.

11 Curriculum Vitae Karen B. Domino, M.D., M.P.H. Page 11 BIBLIOGRAPHY Peer-Reviewed Journal Articles: 1. Domino, K.B. and Domino, E.F.: Effects of scopolamine and methscopolamine on acquisition and retention of rat one- way shuttle box avoidance behavior and total brain acetylcholine. Arch. Int. Pharmacodyn. Ther. 224:248-57, Glasser, S.A., Domino, K.B., Lindgren, L., Parcella, P., Marshall, C., and Marshall, B.E.: Pulmonary pressure and flow during atelectasis. Anesthesiology 58:225-31, Domino, K.B., Wetstein, L., Glasser, S.A., Lindgren, L., Marshall, C., Harken, A.H., and Marshall, B.E.: Influence of P vo2 on blood flow to atelectatic lung. Anesthesiology 59:428-34, Domino, K.B. and Smith T.C.: Electrocautery-induced reprogramming of a pacemaker using a precordial magnet. Anesth. Analg. 62:609-12, Domino, K.B., Chen, L., Alexander, C.M., Williams, J.J., Marshall, C., and Marshall, B.E.: Time course and responses of sustained hypoxic pulmonary vasoconstriction in the dog. Anesthesiology 60:562-6, Domino, K.B., Geer, R.T., LaMantia, K.L., and Klineberg, P.L.: Intraoperative diagnosis of rate-dependent bundle branch block. Can. Anaesth. Soc. J. 31:302-6, Bruno, L.A., Smith, D.S., Bloom, M.J., Domino, K.B., Bagshaw, R.J., Star, A.M., Cohen, A.M., and Lupo, S.E.: Sudden hypotension with a test dose of chymopapain. Anesth. Analg. 63:533-5, Chen, L., Miller, F.L., Williams, J.J., Alexander, C.M., Domino, K.B., Marshall, C., and Marshall, B.E.: Hypoxic pulmonary vasoconstriction is not potentiated by repeated intermittent hypoxia in closed chest dogs. Anesthesiology 63:608-10, Domino, K.B., Borowec, L.W., Alexander, C.M., Williams, J.J., Chen, L., Marshall, C., and Marshall, B.E.: Influence of isoflurane on hypoxic pulmonary vasoconstriction in dogs. Anesthesiology 64:423-9, Accompanied by an Editorial View (Benumof, J.L.: Isoflurane and arterial oxygenation during one-lung ventilation. Anesthesiology 64:419-22, 1986). 10. Domino, K.B., Hlastala, M.P., Eisenstein, B.L., and Cheney, F.W.: Effect of regional alveolar hypoxia on gas exchange in dogs. J. Appl. Physiol. 67:730-5, Forrest, J.B., Rehder, K., Goldsmith, C.H., Cahalan, M.K., Levy, W.J., Strunin, L., Bota, W., Boucek, C.D., Cucchiara, R.F., Dhamee, S., Domino, K.B., Dudman, A.J., Hamilton, W.K., Kampine, J., Kotrly, K.J., Maltby, J.R., Mazloomdoost, M., MacKenzie, R.A., Melnick, B.M., Motoyama, E., Muir, J.J., and Munshi, C.: Multicenter study of general anesthesia. I. Design and patient demography. Anesthesiology 72:252-61, Forrest, J.B., Cahalan, M.K., Rehder, K., Goldsmith, C.H., Levy, W.J., Strunin, L., Bota, W., Boucek, C.D., Cucchiara, R.F., Dhamee, S., Domino, K.B., Dudman, A.J., Hamilton, W.K., Kampine, J., Kotrly, K.J., Maltby, R., Mazloomdoost, M., MacKenzie, R.A., Melnick, B.M., Motoyama, E., Muir, J.J., and Munshi, C.: Multicenter study of general anesthesia. II. Results. Anesthesiology 72:262-8, Domino, K.B., Hlastala, M.P., and Cheney, F.W.: Effect of increased intracranial pressure on regional hypoxic pulmonary vasoconstriction. Anesthesiology 72:490-5, Domino, K.B., and Pinsky, M.R.: The effect of positive end-expiratory pressure on hypoxic pulmonary vasoconstriction in the dog. Am. J. Physiol. (Heart Circ. Physiol.) 259(3):H697-H705, Domino, K.B., Eisenstein, B.L., Cheney, F.W., and Hlastala, M.P.: Pulmonary blood flow and ventilation-perfusion heterogeneity. J. Appl. Physiol. 71:252-8, Domino, K.B., Eisenstein, B.L., Cheney, F.W., and Hlastala, M.P.: Effect of regional alveolar hypoxia on gas exchange in pulmonary edema. Amer. Rev. Respir. Dis. 145:340-7, 1992.

12 Curriculum Vitae Karen B. Domino, M.D., M.P.H. Page 12 Peer-Reviewed Journal Articles (cont d): 17. Domino, K.B., Hemstad, J.R., Lam, A.M., Laohaprasin, V., Mayberg, T.A., Harrison, S.D., Grady, M.S., and Winn, H.R.: Effect of nitrous oxide on ICP following cranial-dural closure in patients undergoing craniotomy. Anesthesiology 77:421-5, Domino, K.B., Lu, Y.M., Eisenstein, B.L., and Hlastala, M.P.: Hypocapnia worsens arterial blood oxygenation and increases V A /Q heterogeneity in canine pulmonary edema. Anesthesiology 78:91-9, Domino, K.B., Swenson, E.R., Polissar, N.L., Lu, Y., Eisenstein, B.L., and Hlastala, M.P.: Effect of inspired CO 2 on ventilation and perfusion heterogeneity during hyperventilation in dogs. J. Appl. Physiol. 75: , Domino, K.B., Eisenstein, B.L., Tran, T., and Hlastala, M.P.: Increased pulmonary perfusion worsens ventilationperfusion matching. Anesthesiology 79:817-26, Ruffle, J., Gleason, M., Domino, K.B., Gersony, W.M., and Zucker, H.A.: Pulmonary edema and transient cardiomyopathy in a previously healthy adolescent after general anesthesia. J. Cardiothorac. Vasc. Anesth. 8:463-70, Hlastala, M.P., Domino, K.B.: Roles of hypoxia and blood flow in modulating V A /Q heterogeneity in the lungs. Adv. Exp. Med. Biol. 345:67-73, Domino, K.B. and Hlastala, M.P.: Hyperventilation in treatment of metabolic acidosis, does not adversely affect pulmonary gas exchange. Anesthesiology 81: , Mayberg, T.S., Lam, A.M., Matta, B.F., Domino, K.B., and Winn, H.R.: Ketamine does not increase cerebral blood flow velocity or intracranial pressure during isoflurane/nitrous oxide anesthesia in patients undergoing craniotomy. Anesth. Analg. 81:84-9, Domino, K.B., Swenson, E.R., and Hlastala, M.P.: Hypocapnia-induced ventilation/perfusion mismatch: A direct or ph-mediated effect? Am. J. Respir. Crit. Care Med. 152:1534-9, Walther, S.M., Domino, K.B., Glenny, R.W., and Hlastala, M.P.: Pulmonary blood flow distribution has a hilar-toperipheral gradient in awake, prone sheep. J. Appl. Physiol. 82:678-85, Walther, S.M., Domino, K.B., Glenny, R.W., and Hlastala, M.P.: Pulmonary blood flow distribution in sheep: Effects of anesthesia, mechanical ventilation, and change in posture. Anesthesiology 87:335-42, Domino, K.B., Emery, M.J., Swenson, E.R., and Hlastala, M.P.: Ventilation heterogeneity is increased in hypocapnic dogs but not in pigs. Respir. Physiol. 11:89-100, Kallas, H.J., Domino, K.B., Glenny, R.W., Anderson, E.A., and Hlastala, M.P.: Pulmonary blood flow distribution changes with low levels of positive end-expiratory pressure. Anesthesiology 88:1291-9, Mann, C.M., Domino, K.B., Walther, S.M., Glenny, R.W., Polissar, M.L., and Hlastala, M.P.: Redistribution of pulmonary blood flow during unilateral hypoxia in prone and supine dogs. J. Appl. Physiol. 84: , Mure, M., Domino, K.B., Glenny R.W., and Hlastala, M.P.: Pulmonary gas exchange improves in the prone position with abdominal distension. Amer. J. Resp. Crit. Care Med. 157: , Mure, M., Domino, K.B., Robertson, H.T., Hlastala, M.P., and Glenny, R.W.: Pulmonary blood flow does not redistribute in dogs with repositions from supine to left lateral position. Anesthesiology 89:483-92, Walther, S.M., Domino, K.B., and Hlastala, M.P.: Effects of posture on blood flow diversion by hypoxic pulmonary vasoconstriction in dogs. Br. J. Anaesth. 81:425-9, Walther, S.M., Domino, K.B., Glenny, R.W., and Hlastala, M.P.: Positive end-expiratory pressure redistributes perfusion to dependent lung regions in supine but not prone sheep. Crit. Care Med. 27:37-45, 1999.

13 Curriculum Vitae Karen B. Domino, M.D., M.P.H. Page 13 Peer-Reviewed Journal Articles (cont d): 35. Domino, K.B., Posner, K.L., Caplan, R.A., and Cheney, F.W.: Awareness during anesthesia: A closed claims analysis. Anesthesiology 90: , Cheney, F.W., Domino, K.B., Caplan, R.A., and Posner, K.L.: Nerve injury associated with anesthesia - A closed claims analysis. Anesthesiology 90:1062-9, Domino, K.B., Anderson, E.A., Polissar, N.L., and Posner, K.L.: Comparative efficacy and safety of ondansetron, droperidol, and metoclopramide for preventing postoperative nausea and vomiting: A meta-analysis. Anesth. Analg. 88: , Domino, K.B., Posner, K.L., Caplan, R.A., Cheney, F.W.: Airway injury during anesthesia: A closed claims analysis. Anesthesiology 91: , Mure, M., Domino, K.B., Lindahl, S.G.E., Hlastala, M.P., Altemeier, W.A., Glenny, R.W.: Regional ventilationperfusion distribution is more uniform in the prone position. J. Appl. Physiol. 88: , Alexander, B.H., Checkoway, H., Nagahama, S.I., Domino, K.B.: Cause-specific mortality risks of anesthesiologists. Anesthesiology 93: , Accompanied by an Editorial View by Berry, A.J., Fleisher, L.A.: New evidence for the existence of old problems. Anesthesiology 93:919-21, Morray, J.P., Geiduschek, J.M., Ramamoorthy, C., Haberkern, C.M., Hackel, A., Caplan, R.A., Domino, K.B., Posner, K. L., and Cheney, F.W.: Anesthesia-related cardiac arrest in children: Initial findings of the Pediatric Perioperative Cardiac Arrest (POCA) Registry. Anesthesiology 93:6-14, Accompanied by an Editorial View by Rothstein, P.: Bringing light to the dark side. Anesthesiology 93:1-3, Lim, C.M., Domino, K.B., Glenny, R.W., Hlastala, M.P.: Effect of increasing perfluorocarbon dose on V A /Q distribution during partial liquid ventilation in acute lung injury. Anesthesiology 94:637-42, Chang, H., Lai-Fook, S.J., Domino, K.B., Schimmel, S., Hildebrandt, J., Robertson, H.T., Glenny, R.W., Hlastala, M.P.: Spatial distribution of ventilation and perfusion in anesthetized dogs in lateral postures. J. Appl. Physiol. 92:745-62, Spitellie, P.H., Holmes, M.A., Domino, K.B.: Awareness during anesthesia. Anesthesiol. Clin. N. Am. 20:317-32, Lee, L.A., Domino, K.B.: The Closed Claims Project: Has it influenced anesthetic practice and outcome? Anesthesiol. Clin. N. Am. 20:247-63, Fitzgibbon, D.R., Posner, K.L., Domino, K.B., Caplan, R.A., Lee, L.A., Cheney, F.W.: Chronic pain management: American Society of Anesthesiologists Closed Claims Project. Anesthesiology 100:98-105, Domino, K.B., Bowdle, T.A., Posner, K.L., Spitellie, P.H., Lee, L.A., Cheney, F.W.: Injuries and liability related to central vascular catheters: A closed claims analysis. Anesthesiology 100:1411-8, Featured in This Month in Anesthesiology. 48. Lee, L.A., Posner, K.L., Domino, K.B., Caplan, R.A., Cheney, F.W.: Injuries associated with regional anesthesia in the 1980s and 1990s: A closed claims analysis. Anesthesiology 101:143-52, Sebel, P.S., Bowdle, T.A., Ghoneim, M.M., Rampil, I.J., Padilla, R.E., Gan, T.J., Domino, K.B.: The incidence of awareness during anesthesia: A multicenter U.S. study. Anesth Analg 99:833-9, Domino, K.B., Hornbein, T.F., Polissar N.L., Renner G., Johnson, J., Alberti, S., Hankes, L.: Risk factors for relapse in health care professionals with substance use disorders. JAMA 293: , Accompanied by an editorial by Gastfriend, D.R.: Physician substance abuse and recovery: What does it mean for physicians - and everyone else? (JAMA 293:1513-5, 2005).

14 Curriculum Vitae Karen B. Domino, M.D., M.P.H. Page 14 Peer-Reviewed Journal Articles (cont d): 51. Peterson, G.N., Domino, K.B., Caplan, R.A., Posner, K.L., Lee, L.A., Cheney, F.W.: Management of the difficult airway: A closed claims analysis. Anesthesiology 103:33-9, Lee, L.A., Domino, K.B.: Complications associated with peripheral nerve blocks: Lessons from the ASA Closed Claims Project. Intl Anesthesiol Clin 43:111-8, Peretz, C., Alexander B.H., Nagahama S.I., Domino, K.B., Checkoway H.: Parkinson s disease mortality among male anesthesiologists and internists. Mov Disord 20:1614-7, Bhananker, S.M., Posner, K.L., Cheney, F.W., Caplan, R.A., Lee, L.A., Domino, K.B.: Injury and liability associated with monitored anesthesia care: A closed claims analysis. Anesthesiology 104:228-34, Accompanied by an editorial by Hug, C.C.: MAC should stand for maximum anesthesia caution, not minimal anesthesiology care. (Anesthesiology 104:221-3, 2006). Selected for Anesthesiology CME program. 55. Chang, H., Lai-Fook, S.J., Domino, K.B., Schimmel, C., Hildebrandt, J., Robertson, H.T., Glenny, R.W., Halastala, M.P.: Ventilation and perfusion distribution during altered PEEP in the left lung in the left lateral decubitus posture with unchanged tidal volume in dogs. Chin J Physiol 49:74-82, Chang, H., Lai-Fook, S.J., Domino, K.B., Schimmel, C., Hildebrandt, J., Robertson, H.T., Glenny, R.W., Halastala, M.P.: Redistribution of blood flow and lung volume between lungs in lateral decubitus postures during unilateral atelectasis and PEEP. Chin J Physiol 49:83-95, Erratum in Chin J Physiol 49:167, Robbertze, R., Posner, K.L., Domino, K.B.: Closed claims review of anaesthesia for procedures outside the operating room. Curr Opin Anaesthesiology 19:436-42, Lee, L.A., Roth, S., Posner, K.L., Cheney, F.W., Caplan, R.A., Newman, N.J., Domino, K.B.: The American Society of Anesthesiologists Postoperative Visual Loss Registry: Analysis of 93 spine surgery cases with postoperative visual loss. Anesthesiology 105:652-9, Accompanied by an editorial by Warner, M.A.: Postoperative visual loss: Experts, data and practice. Anesthesiology 105:641-2, Selected for Anesthesiology CME program. 59. Rozet, I., Muangman, S., Vavilala, M.S., Lee, L.A., Souter, M.J., Domino, K.B., Slimp, J.C., Goodkin, R, Lam, A.M.: Clinical experience with dexmedetomidine for implantation of deep brain stimulators in Parkinson s Disease. Anesth Analg 103:1224-8, Cheney, F.W., Posner, K.L., Lee, L.A., Caplan, R.A., Domino, K.B.: Trends in anesthesia-related death and brain damage: A closed claims analysis. Anesthesiology 105:1081-6, Accompanied by an editorial by Lagasse. R.S.: To see or not to see. Anesthesiology 105:1071-3, Jimenez, N., Posner, K.L., Cheney, F.W., Caplan, R.A., Lee, L.A., Domino, K.B.: An update on pediatric anesthesia liability: A closed claims analysis. Anesth Analg 104:147-53, Burkman J.M., Posner K.L., Domino, K.B.: Analysis of clinical variables associated with recrudescence after malignant hyperthermia reactions. Anesthesiology 106:901-6, Accompanied by an editorial by Hopkins P.M.: Recrudescence of malignant hyperthermia. Anesthesiology 106:893-4, Selected for Anesthesiology CME program. 63. Kent, C.D, Domino, K. B.: Awareness: Practice, standards, and the law. Best Pract Res Clin Anaesthesiol 21(3):369-83, Bhananker S.M., Ramamoorthy C, Geiduschek, J.M., Posner, K.L., Domino, K.B., Haberkern C.M., Campos J.S., Morray J.P.: Anesthesia-related cardiac arrest in children: Update from the Pediatric Perioperative Cardiac Arrest (POCA) Registry. Anesth Analg 105:344-50, Accompanied by an editorial by Davis P.J.: When assessing what we know we don t know is not enough: Another perspective on pediatric outcomes. Anesth Analg 105:301-3, Selected for Anesth Analg CME program.

15 Curriculum Vitae Karen B. Domino, M.D., M.P.H. Page 15 Peer-Reviewed Journal Articles (cont d): 65. Rozet, I., Domino, K.B.: Respiratory care. Best Pract Res Clin Anaesthesiol 21(4):465-82, Lee, L.A., Posner, K.L., Cheney, F.W., Caplan, R.A., Domino, K.B.: Complications associated with eye blocks and peripheral nerve blocks: an American Society of Anesthesiologists closed claims analysis. Reg Anesth Pain Med 33(5):416-22, Bishop, M.J., Souders, J.E., Peterson, C.M., Henderson, W.G., Domino, K.B.: Factors associated with unanticipated day of surgery deaths in Department of Veterans Affairs hospitals. Anesth Analg 107: , Accompanied by an editorial by Lagasse R.S.: The right stuff: Veterans Affairs National Surgical Quality Improvement Project. Anesth Analg 107:1772-4, Davies, J.M., Posner, K.L., Lee, L.A., Cheney, F.W., Domino, K.B.: Liability associated with obstetric anesthesia: a closed claims analysis. Anesthesiology 110:131-9, Accompanied by an editorial by Leighton, B.L.: Why obstetric anesthesiologists get sued. Anesthesiology 110:8-9, Pasternak, J.J., McGregor, D.G., Lanier W.L., Schroeder, D.R., Rusy, D.A., Hindman, B., Clarke, W., Torner, J., Todd, M.M., IHAST Investigators: Effect of nitrous oxide use on long-term neurologic and neuropsychological outcome in patients who received temporary proximal artery occlusion during cerebral aneurysm clipping surgery. Anesthesiology. 110(3):563-73, Bhananker, S.M., Liau, D.W., Kooner, P.K., Posner, K.L., Caplan, R.A., Domino, K.B.: Liability related to peripheral venous and arterial catheterization: a closed claims analysis. Anesth Analg 109:124-9, Todd, M.M., Hindman, B.J., Clarke, W.R., Torner, J.C., Weeks, J.B., Bayman, E.O., Shi, Q., Spofford, C.M., IHAST Investigators: Perioperative fever and outcome in surgical patients with aneurysmal subarachnoid hemorrhage. Neurosurgery 64(5): , Metzner J., Posner, K.L., Domino, K.B.: The risk and safety of anesthesia at remote locations: the US closed claims analysis. Curr Opin Anaesthesiol 22:502-8, Kent C.D., Domino, K.B.: Depth of anesthesia. Curr Opin Anaesthesiol 2009; 22: Hindman, B.J., Bayman. E.O., Pfisterer W.K., Torner, J.C., Todd, M.M., IHAST Investigators: No association between intraoperative hypothermia or supplemental protective drug and neurologic outcomes in patients undergoing temporary clipping during cerebral aneurysm surgery: findings from the Intraoperative Hypothermia for Aneurysm Surgery Trial. Anesthesiology 112(1):86-101; Fitzgibbon, D.R., Rathmell, J.P., Michna E., Stephens, L.S., Posner, K.L., Domino, K.B.: Malpractice claims associated with medication management for chronic pain. Anesthesiology 112:948-56, Accompanied by an editorial by Jamison RN, Clark JD: Opioid medication management: Clinician beware! (Anesthesiology 112:777-8, 2010). 76. Ramamoorthy, C., Haberkern, C.M., Bhananker, S.M., Domino, K.B., Posner, K.L., Campos, J.S., Morray, J.P.: Anesthesia-related cardiac arrest in children with heart disease: Data from the Pediatric Perioperative Cardiac Arrest (POCA) Registry. Anesth Analg 110: , Accompanied by an editorial by Steven, J.M.: Congenital heart disease and anesthesia-related cardiac arrest: connecting the dots. (Anesth Analg 110:1255-6, 2010). 77. Metzner, J., Domino, K.B.: Risks of anesthesia or sedation outside the operating room: the role of the anesthesia care provider. Curr Opin Anaesthesiol 23:523-31, Nguyen, H.P., Zaroff, J.G., Bayman, E.O., Gelb, A.W., Todd, M.M., Hindman B.J., IHAST-MIDS and IHAST Investigators. Perioperative hpothermia (33 degrees C) does not increase the occurrence of cardiovascular events in patients undergoing cerebral aneurysm surgery: findings from the Intraoperative Hypothermia for Aneurysm Surgery Trial. Anesthesiology 113(2):327-42, 2010.

16 Curriculum Vitae Karen B. Domino, M.D., M.P.H. Page 16 Peer-Reviewed Journal Articles (cont d): 79. Metzner, J., Evans, J.L., Domino, K.B.: Life-threatening hyperkalemia during radiofrequency ablation of hepatocellular carcinoma. (case report) J Clin Anesth 22:473-6, Rathmell, J.P., Michna, E., Fitzgibbon, D.R., Stephens, L.S., Posner, K.L., Domino, K.B.: Injury and liability associated with cervical procedures for chronic pain. Anesthesiology 114:918-26, Hindman, B.J., Palecek J.P., Posner, K.L., Traynelis, V.C., Lee, L.A., Sawin P.D., Tredway T.L., Todd, M.M., Domino, K.B: Cervical spinal cord, root, and bony spine injuries. A Closed Claim analysis. Anesthesiology 114:782-95, Accompanied by an editorial by Lanier W.L., Warner M.A.: New perioperative cervical injury: medical and legal implications for patients and anesthesia providers. (Anesthesiology 114:729-31, 2011). 82. Bruchas, R.R., Kent, C.D., Wilson, H.D., Domino, K.B.: Anesthesia awareness: narrative review of psychological sequelae, treatment, and incidence. J Clin Psychol Med Settings 18(3):257-67, Metzner, J., Posner, K.L., Lam, M.S., Domino, K.B.: Closed claims analysis. Best Pract Res Clin Anaesthesiol 25:263-76, Lee L.A., Posner, K.L., Kent, C.D., Domino, K.B.: Complications associated with peripheral nerve blocks: Lessons from the ASA Closed Claims Project. Intl Anesthesiol Clin 49(3):56-67, Lee, L.A., Stephens, L.S., Fligner, C.L., Posner, K.L., Cheney, F.W., Caplan, R.A., Domino, K.B.: Autopsy utilization in medicolegal defense of anesthesiologists. Anesthesiology 115:713-5, Accompanied by an editorial by McLemore, J.L., Garvin, A.J.: Autopsy and malpractice considerations. (Anesthesiology 115: 685-6, 2011). 86. Postoperative Visual Loss Study Group: Risk factors associated with ischemic optic neuropathy after spinal fusion surgery. Anesthesiology 116:15-24, Accompanied by an editorial by Warner, M.A.: Cracking open the door on perioperative visual loss. (Anesthesiology 116:1-2, 2012). 87. Olivar, H., Sharar, S.R., Stephens, L.S., Posner, K.L., Domino, K.B.: Similar liability for trauma and non-trauma surgical anesthesia: A closed claims analysis. Anesth Analg 115: , Kent, C., Mashour, G., Metzger, N., Posner, K., Domino, K.: Psychological impact of unexpected explicit recall of events occurring during surgery performed under sedation, regional anaesthesia, and general anaesthesia: Data from the Anesthesia Awareness Registry. Br J Anaesth 110(3):381-7, Selected for CME. 89. Mehta, S.P., Bhananker, S.M., Posner, K.L., Domino, K.B.: Operating room fires: a closed claims analysis. Anesthesiology 118(5):1133-9, Mehta, S.P., Eisenkraft, J.B., Posner, K.L., Domino, K.B.: Patient injuries from anesthesia gas delivery equipment: A closed claims update. Anesthesiology 119(4):788-95, Cote, C.J., Posner, K.L., Domino, K.B.: Death or neurologic injury after tonsillectomy in children with a focus on obstructive sleep apnea: Houston, we have a problem! Anesth Analg Anesth Analg 118: , Accompanied by an editorial by Brown, K.A., Brouillette, R.T. The elephant in the room: Lethal apnea at home after adenotonsillectomy. (Anesth Analg 118:1157-9, 2014). 92. Deo, A.K., Borson, S., Link, J.M., Domino, K., Eary, J.F., Ke, B., Richards, T.L., Mankoff, D.A., Minoshima, S., O'Sullivan, F., Eyal, S., Hsiao, P., Maravilla, K., Unadkat, J.D.: Activity of P-glycoprotein, a β-amyloid transporter at the blood-brain barrier, is compromised in patients with mild Alzheimer disease. J Nucl Med published online May 19, Doi: /jnumed Maxwell, B.G., Posner, K.L., Wong, J.K., Oakes, D.A., Kelly, N.E., Domino, K.B., Ramamoorthy, C.: Factors contributing to adverse perioperative events in adults with congenital heart disease: a structured analysis of cases from the Closed Claims Project. Congenit Heart Dis May 28, 2014 [Epub ahead of print].

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18 Curriculum Vitae Karen B. Domino, M.D., M.P.H. Page 18 Book Chapters/Other Articles (cont d): 3. Domino, K.B.: Fluid management for the neurosurgical patient, in Barash, P.G. (ed.): ASA Refresher Courses in Anesthesiology, Volume 18. Philadelphia, J.B. Lippincott, 1990, Chapter 8, pp Domino, K.B.: Care of the acutely unstable patient, in Cottrell, J.E. and Smith, D.S. (eds.): Anesthesia and Neurosurgery, 3rd Edition. New York, C.V. Mosby Company, 1994, Chapter 12, pp Domino, K.B.: Pathophysiology of head injury. II. Secondary systemic effects, in Lam, A.M. (ed.): Anesthetic Considerations for Acute Head Injury. New York, C.V. Mosby Company, 1995, Chapter 3, pp Domino, K.B.: Anesthetic management of the patient with chronic obstructive pulmonary disease. Curr. Rev. Clin. Anesth. 16:85-96, Domino, K.B.: Avoiding anesthetic disaster for the patient with pulmonary disease. Sem. Anesth. 14:165-78, Domino, K.B.: Pulmonary function and dysfunction in the traumatized patient. Anesthesiol. Clin. N. Am. 14:59-84, Krane, E.J. and Domino, K.B.: Pediatric neuroanesthesia, in Motoyama, E.K., Davis, P.J. (eds.): Smith s Anesthesia for Infants and Children, 6th Edition. New York, C.V. Mosby Company, 1996, Chapter 16, pp Domino, K.B.: Silicosis, in Roizen, M.F. and Fleisher, L.A. (eds.): Essence of Anesthesia Practice. Philadelphia, W.B. Saunders, 1996, pp Domino, K.B.: Anesthetic modulation of pulmonary vascular tone, in Biebuyck, M.B., Lynch, C., III, Maze, M., Saidman, L.J., Yaksh, T.L., and Zapol, W.M. (eds.): Anesthesia: Biologic Foundations. Philadelphia, Lippincott- Raven, 1998, Chapter 76, pp Swenson E.R., Domino, K.B., and Hlastala, M.P.: Physiological Effects of Oxygen and Carbon Dioxide, in Hlastala, M.P. and Robertson, H.T. (eds.): Complexity in Structure and Function of the Lung. New York, Marcel Dekker, Inc., 1998, Lung Biology Series, Vol. 121, pp Domino, K.B.: Anesthesia for the respiratory cripple. Anesthesiol. Clin. N. Am. 16(1): , Domino, K.B.: Respiratory Care of the Neurological Patient, in Newfield, P. and Cottrell, J.E. (eds.): Handbook of Neuroanesthesia, 3rd Edition. Baltimore, Lippincott, Williams & Wilkins, 1999, Chapter 21, pp Domino, K.B.: Closed claims analysis as a tool for outcomes assessment, in Tuman, K.J. (ed.): Outcome Measurements in Cardiovascular Medicine. Baltimore, Lippincott, Williams & Wilkins, 1999, pp Domino, K.B.: Anesthesiology issues in general surgery: Evaluation, preparation, and management of the surgical patient with respiratory disease. Contemporary Surgery, 54:41-9, Domino, K.B.: Perioperative hypertension. Am. J. Anesthesiol., 26:259-65, Domino, K.B.: Care of the acutely unstable patient, in Cottrell, J.E. and Smith, D.S. (eds.): Anesthesia and Neurosurgery, 4th Edition. St. Louis, Mosby, 2001, pp Domino, K.B. and Aitkenhead, A.R.: Medicolegal consequences of awareness during anesthesia, in Ghoneim, M. (ed): Awareness During Anesthesia. Woburn, MA, Butterworth Heinemann, 2001, pp Domino, K.B.: Role of closed claims study in improving outcome, in Fleisher, L.A. and Prough, D.S. (eds): Problems in Anesthesia: Quality, Safety, Risk and Outcomes in Anesthesiology. Philadelphia, Lippincott Williams & Wilkins, 2001, Vol. 13(4), pp Domino, K.B.: Silicosis, in Roiten, M.F. and Fleisher, L.A.: Essence of Anesthesiology Practice, 2nd Edition. Philadelphia, W.B. Saunders Company, 2002, pp. 304.

19 Curriculum Vitae Karen B. Domino, M.D., M.P.H. Page 19 Book Chapters/Other Articles (cont d): 22. Bhananker, S.M., Domino, K.B.: What actions can be used to prevent peripheral nerve injury? in Fleisher, L.A.: Evidence-Based Practice of Anesthesiology. Orlando, W.B. Saunders Company, 2004, pp Hooks, M.A., Domino, K.B.: Asthma: Preoperative and intraoperative management, and postoperative care. Current Reviews in Clinical Anesthesia 2004, a Frank Moya Continuing Education Program at Lee, L.A., Domino, K.B.: Complications associated with peripheral nerve blocks: Lessons from the ASA Closed Claims Project. Int Anesthesiol Clin 43(3): , Bowdle, T.A., Edwards, M., Domino, K.B.: Reducing error in cardiac anesthesiology, in Lake C., Konstadt S.N., Kaplan, J.A., et al. (eds): Cardiac Anesthesia. 5th Edition. Philadelphia, W.B. Saunders Company, 2006, pp Krane, E.J., Philip, B.M., Yeh, K.K., Domino, K.B.: Anesthesia for Pediatric Neurosurgery (Chapter 40), in Motoyama, E.K., Davis, P.J. (eds): Smith s Anesthesia for Infants and Children, 7 th Edition. Philadelphia, Mosby Elsevier, 2006, pp Kent, C.D., Domino, K.B.: Update on unintended intraoperative awareness, in Johnson J.O. and McLoughlin, T.M. (eds): Advances in Anesthesia. Missouri, Mosby Elsevier, 2006, Vol. 24, pp Lee, L.A., Domino, K.B.: Complications associated with regional anesthesia: An American Society of Anesthesiologist closed claims analysis, in Finucane, F. (ed): Complications of Regional Anesthesia (2 nd ed). New York, Springer, 2007, pp Rozet, I., Domino, K.B.: Respiratory care of the neurosurgical patient, in Newfield P., Cottrell J.E. (eds): Handbook of Neuroanesthesia, 4 th Edition. Philadelphia, Lippincott, Williams & Wilkins, 2007, pp Lee, L.A., Caplan, R.A., Domino, K.B.: Complications associated with regional anesthesia and pain medicine: Lessons from the ASA Closed Claims Project, in Neal, J.M., Rathmell, J.P. (eds): Complications in Regional Anesthesia and Pain Management. Philadelphia, Saunders/Elsevier Cole, D.J., Domino, K.B.: Depth of anesthesia: Clinical applications, awareness and beyond, in Schwartz A.J. (ed): ASA Refresher Courses in Anesthesiology. Philadelphia, Lippincott Williams & Wilkins 2007, 35(1): Lee, L.A., Domino, K.B.: How not to end up in a closed claims file: Lessons learned from the ASA Closed Claims Project, in Marcucci C. et al. (eds): Avoiding Common Anesthesia Errors. Philadelphia, Lippincott, Williams & Wilkins, 2008, pp Domino, K.B., Caplan, R.A., Morray, J.P., Lee, L.A.: The American Society of Anesthesiologists closed claims project and its registries, in Schwartz, A.J. (ed): ASA Refresher Courses in Anesthesiology. Philadelphia, Lippincott Williams & Wilkins 2008, 36: Posner, K.L., Domino, K.B.: Anesthetic risk, quality of care, and professional liability, in Barash, et al. (eds): Clinical Anesthesia (6 th ed). Philadelphia, Lippincott, Williams & Wilkins 2009, pp Bhananker, S.M., Domino, K.B.: What actions can be used to prevent peripheral nerve injury? in Fleisher, L.A. (ed): Evidence-Based Practice of Anesthesiology (2 nd ed). Philadelphia, Saunders/Elsevier 2009, pp Kent, C.D., Domino, K.B.: Medicolegal consequences of intraoperative awareness, in Mashour, G.A. (ed): Consciousness, Awareness, and Anesthesia. New York, Cambridge University Press 2010, pp Rozet, I., Domino, K.B.: Care of the acutely unstable patient, in Cottrell, J.E., Young, W.L. (eds): Anesthesia and Neurosurgery (5 th ed). Philadelphia, Mosby Elsevier 2010, pp Vitin, A.A., Domino, K.B.: Silicosis, in Fleisher L.A., Roizen, M.F. (eds): Essence of Anesthesia Practice (3 rd ed). Philadelphia, Elsevier 2011, pp

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