Local Coverage Determination (LCD): Immunohistochemistry (L34369)

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1 Local Coverage Determination (LCD): Immunohistochemistry (L34369) Contractor Information Contractor Name CGS Administrators, LLC LCD Information Document Information LCD ID L34369 Original ICD9 LCD ID L31873 LCD Title Immunohistochemistry AMA CPT/ADA CDT Copyright Statement CPT only copyright American Medical Association. All Rights Reserved. CPT is a registered trademark of the American Medical Association. Applicable FARS/DFARS Apply to Government Use. Fee schedules, relative value units, conversion factors and/or related components are not assigned by the AMA, are not part of CPT, and the AMA is not recommending their use. The AMA does not directly or indirectly practice medicine or dispense medical services. The AMA assumes no liability for data contained or not contained herein. The Code on Dental Procedures and Nomenclature (Code) is published in Current Dental Terminology (CDT). Copyright American Dental Association. All rights reserved. CDT and Original Effective Date For services performed on or after 10/01/2014 Revision Effective Date For services performed on or after 10/01/2014 Revision Ending Date N/A Retirement Date N/A Notice Period Start Date N/A Notice Period End Date N/A

2 CDT2010 are trademarks of the American Dental Association. CMS National Coverage Policy Language quoted from Centers for Medicare and Medicaid Services (CMS), National Coverage Determinations (NCDs) and coverage provisions in interpretive manuals is italicized throughout the policy. NCDs and coverage provisions in interpretive manuals are not subject to the Local Coverage Determination (LCD) Review Process (42 CFR [b] and 42 CFR 426 [Subpart D]). In addition, an administrative law judge may not review an NCD. See Section 1869(f)(1)(A)(i) of the Social Security Act. Unless otherwise specified, italicized text represents quotation from one or more of the following CMS sources: Title XVIII of the Social Security Act (SSA): Section 1862(a)(1)(A) excludes expenses incurred for items or services which are not reasonable and necessary for the diagnosis or treatment of illness or injury or to improve the functioning of a malformed body member. Section 1833(e) prohibits Medicare payment for any claim which lacks the necessary information to process the claim. Code of Federal Regulations: 42 CFR, Section , indicates that diagnostic tests may only be ordered by the treating physician (or other treating practitioner acting within the scope of his or her license and Medicare requirements)who furnishes a consultation or treats a beneficiary for a specific medical problem and who uses the results in the management of the beneficiary's specific medical problem. Tests not ordered by the physician (or other qualified nonphysician provider) who is treating the beneficiary are not reasonable and necessary (see Sec (k)(1) of this chapter). A pathologist may perform additional tests under the following circumstances: These services are medically necessary so that a complete and accurate diagnosis can be reported to the treating physician/practitioner; The results of the tests are communicated to and are used by the treating physician/practitioner in the treatment of the beneficiary; and The pathologist documents in his/her report why additional testing was done. CMS Transmittal No. 1770, Publication , Medicare Claims Processing Manual, Change Request #6520, July 10, 2009, Medicare contractor annual update of the international classification of diseases, ninth revision, clinical modification (ICD9CM).

3 Coverage Guidance Coverage Indications, Limitations, and/or Medical Necessity Abstract: Immunohistochemistry (IHC) combines anatomical, immunological and biochemical techniques for the identification of specific tissue components by means of a specific antigen/antibody reaction tagged with a visible label. IHC makes it possible to visualize the distribution and localization of specific cellular components within a cell or tissue. The principle of immunohistochemistry has existed since the 1930s, but it was not until 1942 that the first immunohistochemistry study was reported. Coons and his colleagues used labeled antibodies to localize Pneumococcal antigens in infected tissues. Since then improvements have been made in protein conjugation, tissue fixation methods, detection labels and microscopes, making immunohistochemistry an essential tool in many laboratories. Today, the most popular methods of detection are with enzymeantibody and fluorophoreantibody conjugates. After the antigenantibody reaction, the enzyme label is reacted with a substrate to yield an intensely colored product that can be analyzed with an ordinary light microscope. A further advantage of using enzyme labeled systems is the option to make the product electron dense for electron microscopy. This LCD documents CGS approved indications and limitations of coverage for this laboratory test. Indications: Immunohistochemistry is useful in the evaluation of various malignancies, for diagnosis, staging, and the estimation of prognosis. It is also useful for the identification of a number of infectious organisms. Limitations: It is unusual to require more than 10 immunohistochemical analyses in order to adequately evaluate a sample of tissue. Utilization beyond this threshold should be supported in the medical record, and may be subject to review. Other Comments: For claims submitted to the Part A MAC: this coverage determination also applies within states outside the primary geographic jurisdiction with facilities that have nominated CGS Administrators, LLC to process their claims. Bill type codes only apply to providers who bill these services to the Part A MAC. Bill type codes do not apply to physicians, other professionals and suppliers who bill these services to the carrier or Part B MAC. Limitation of liability and refund requirements apply when denials are likely, whether based on medical necessity or other coverage reasons. The provider/supplier must notify the beneficiary in

4 writing, prior to rendering the service, if the provider/supplier is aware that the test, item or procedure may not be covered by Medicare. The limitation of liability and refund requirements do not apply when the test, item or procedure is statutorily excluded, has no Medicare benefit category or is rendered for screening purposes. For dates of service on or after April 1, 2010, bill type 77X should be used to report FQHC services. For outpatient settings other than CORFs, references to "physicians" throughout this policy include nonphysicians, such as nurse practitioners, clinical nurse specialists and physician assistants. Such nonphysician practitioners, with certain exceptions, may certify, order and establish the plan of care for services as authorized by State law. (See Sections 1861[s][2] and 1862[a][14] of Title XVIII of the Social Security Act; 42 CFR, Sections , , and ; 58 FR 18543, April 7, 2000.) Coding Information Bill Type Codes: Contractors may specify Bill Types to help providers identify those Bill Types typically used to report this service. Absence of a Bill Type does not guarantee that the policy does not apply to that Bill Type. Complete absence of all Bill Types indicates that coverage is not influenced by Bill Type and the policy should be assumed to apply equally to all claims. 011x Hospital Inpatient (Including Medicare Part A) 012x Hospital Inpatient (Medicare Part B only) 013x Hospital Outpatient 014x Hospital Laboratory Services Provided to Nonpatients 021x Skilled Nursing Inpatient (Including Medicare Part A) 022x Skilled Nursing Inpatient (Medicare Part B only) 023x Skilled Nursing Outpatient 071x Clinic Rural Health 073x Clinic Freestanding 077x Clinic Federally Qualified Health Center (FQHC) 085x Critical Access Hospital Revenue Codes: Contractors may specify Revenue Codes to help providers identify those Revenue Codes typically used to report this service. In most instances Revenue Codes are purely advisory; unless specified in the policy services reported under other Revenue Codes are equally subject to this coverage determination. Complete absence of all Revenue Codes indicates that coverage is not influenced by Revenue Code and the policy should be assumed to apply equally to all Revenue Codes.

5 Revenue codes only apply to providers who bill these services to the Part A MAC. Revenue codes do not apply to physicians, other professionals and suppliers who bill these services to the carrier or Part B MAC. Please note that not all revenue codes apply to every type of bill code. Providers are encouraged to refer to the FISS revenue code file for allowable bill types. Similarly, not all revenue codes apply to each CPT/HCPCS code. Providers are encouraged to refer to the FISS HCPCS file for allowable revenue codes. All revenue codes billed on the inpatient claim for the dates of service in question may be subject to review Laboratory Pathology General Classification 0311 Laboratory Pathology Cytology 0312 Laboratory Pathology Histology 0314 Laboratory Pathology Biopsy 0319 Laboratory Pathology Other Laboratory Pathology 0521 FreeStanding Clinic Clinic Visit by Member to RHC/FQHC 096X Professional Fees General Classification 0971 Professional Fees Laboratory CPT/HCPCS Codes Group 1 Paragraph: N/A Group 1 Codes: IMMUNOHISTOCHEMISTRY OR IMMUNOCYTOCHEMISTRY, PER SPECIMEN; G0461 FIRST SINGLE OR MULTIPLEX ANTIBODY STAIN IMMUNOHISTOCHEMISTRY OR IMMUNOCYTOCHEMISTRY, PER SPECIMEN; G0462 EACH ADDITIONAL SINGLE OR MULTIPLEX ANTIBODY STAIN (LIST SEPARATELY IN ADDITION TO CODE FOR PRIMARY PROCEDURE) ICD10 Codes that Support Medical Necessity Group 1 Paragraph: It is the responsibility of the provider to code to the highest level specified in the ICD10CM. The correct use of an ICD10CM code does not assure coverage of a service. The service must be reasonable and necessary in the specific case and must meet the criteria specified in this determination. Group 1 Codes:

6 Group 1Codes ICD10 Code Description A18.14 Tuberculosis of prostate A63.0 Anogenital (venereal) warts A74.9 Chlamydial infection, unspecified B07.8 Other viral warts B07.9 Viral wart, unspecified B15.0 Hepatitis A with hepatic coma B15.9 Hepatitis A without hepatic coma B16.0 B16.2 Acute hepatitis B with deltaagent with hepatic coma Acute hepatitis B without deltaagent with hepatic coma B16.9 Acute hepatitis B without deltaagent and without hepatic coma B17.0 Acute delta(super) infection of hepatitis B carrier B17.10 Acute hepatitis C without hepatic coma B17.11 Acute hepatitis C with hepatic coma B17.2 Acute hepatitis E B17.8 Other specified acute viral hepatitis B18.0 B18.2 Chronic viral hepatitis B with deltaagent Chronic viral hepatitis C B18.8 Other chronic viral hepatitis B19.0 Unspecified viral hepatitis with hepatic coma B19.10 Unspecified viral hepatitis B without hepatic coma B19.11 Unspecified viral hepatitis B with hepatic coma B19.20 Unspecified viral hepatitis C without hepatic coma B19.21 Unspecified viral hepatitis C with hepatic coma B25.1 Cytomegaloviral hepatitis B25.2 Cytomegaloviral pancreatitis B33.8 Other specified viral diseases B34.1 B34.4 Enterovirus infection, unspecified Papovavirus infection, unspecified B34.8 Other viral infections of unspecified site B96.81 Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere B97.19 Other enterovirus as the cause of diseases classified elsewhere B97.29 Other coronavirus as the cause of diseases classified elsewhere B97.5 B97.7 Reovirus as the cause of diseases classified elsewhere Papillomavirus as the cause of diseases classified elsewhere B97.81 Human metapneumovirus as the cause of diseases classified elsewhere B97.89 Other viral agents as the cause of diseases classified elsewhere C00.0 C00.9 Malignant neoplasm of external upper lip Malignant neoplasm of lip, unspecified C01 Malignant neoplasm of base of tongue

7 C02.0 C02.4 Malignant neoplasm of dorsal surface of tongue Malignant neoplasm of lingual tonsil C02.8 Malignant neoplasm of overlapping sites of tongue C02.9 Malignant neoplasm of tongue, unspecified C03.0 Malignant neoplasm of upper gum C03.1 Malignant neoplasm of lower gum C03.9 Malignant neoplasm of gum, unspecified C04.0 Malignant neoplasm of anterior floor of mouth C04.1 Malignant neoplasm of lateral floor of mouth C04.8 Malignant neoplasm of overlapping sites of floor of mouth C04.9 Malignant neoplasm of floor of mouth, unspecified C05.0 C05.2 Malignant neoplasm of hard palate Malignant neoplasm of uvula C05.8 Malignant neoplasm of overlapping sites of palate C06.0 C06.2 Malignant neoplasm of cheek mucosa Malignant neoplasm of retromolar area C06.89 Malignant neoplasm of overlapping sites of other parts of mouth C06.9 Malignant neoplasm of mouth, unspecified C07 Malignant neoplasm of parotid gland C08.0 Malignant neoplasm of submandibular gland C08.1 Malignant neoplasm of sublingual gland C08.9 Malignant neoplasm of major salivary gland, unspecified C09.0 Malignant neoplasm of tonsillar fossa C09.1 Malignant neoplasm of tonsillar pillar (anterior) (posterior) C09.8 Malignant neoplasm of overlapping sites of tonsil C10.0 C10.4 Malignant neoplasm of vallecula Malignant neoplasm of branchial cleft C10.8 Malignant neoplasm of overlapping sites of oropharynx C10.9 Malignant neoplasm of oropharynx, unspecified C11.0 C11.3 Malignant neoplasm of superior wall of nasopharynx Malignant neoplasm of anterior wall of nasopharynx C11.8 Malignant neoplasm of overlapping sites of nasopharynx C11.9 Malignant neoplasm of nasopharynx, unspecified C12 Malignant neoplasm of pyriform sinus C13.0 C13.2 Malignant neoplasm of postcricoid region Malignant neoplasm of posterior wall of hypopharynx C13.8 Malignant neoplasm of overlapping sites of hypopharynx C13.9 Malignant neoplasm of hypopharynx, unspecified C14.0 Malignant neoplasm of pharynx, unspecified C14.2 Malignant neoplasm of Waldeyer's ring C14.8 Malignant neoplasm of overlapping sites of lip, oral cavity and pharynx C15.3 C15.5 Malignant neoplasm of upper third of esophagus Malignant neoplasm of lower third of esophagus

8 C15.8 Malignant neoplasm of overlapping sites of esophagus C15.9 Malignant neoplasm of esophagus, unspecified C16.0 C16.6 Malignant neoplasm of cardia Malignant neoplasm of greater curvature of stomach, unspecified C16.8 Malignant neoplasm of overlapping sites of stomach C16.9 Malignant neoplasm of stomach, unspecified C17.0 C17.3 Malignant neoplasm of duodenum Meckel's diverticulum, malignant C17.8 Malignant neoplasm of overlapping sites of small intestine C17.9 Malignant neoplasm of small intestine, unspecified C18.0 C18.9 Malignant neoplasm of cecum Malignant neoplasm of colon, unspecified C19 Malignant neoplasm of rectosigmoid junction C20 Malignant neoplasm of rectum C21.0 C21.2 Malignant neoplasm of anus, unspecified Malignant neoplasm of cloacogenic zone C21.8 Malignant neoplasm of overlapping sites of rectum, anus and anal canal C22.0 C22.4 Liver cell carcinoma Other sarcomas of liver C22.7 Other specified carcinomas of liver C22.9 Malignant neoplasm of liver, not specified as primary or secondary C23 Malignant neoplasm of gallbladder C24.0 Malignant neoplasm of extrahepatic bile duct C24.1 Malignant neoplasm of ampulla of Vater C24.8 Malignant neoplasm of overlapping sites of biliary tract C24.9 Malignant neoplasm of biliary tract, unspecified C25.0 C25.4 Malignant neoplasm of head of pancreas Malignant neoplasm of endocrine pancreas C25.7 Malignant neoplasm of other parts of pancreas C25.8 Malignant neoplasm of overlapping sites of pancreas C25.9 Malignant neoplasm of pancreas, unspecified C26.0 Malignant neoplasm of intestinal tract, part unspecified C26.1 Malignant neoplasm of spleen C26.9 Malignant neoplasm of illdefined sites within the digestive system C30.0 Malignant neoplasm of nasal cavity C30.1 Malignant neoplasm of middle ear C31.0 C31.3 Malignant neoplasm of maxillary sinus Malignant neoplasm of sphenoid sinus C31.8 Malignant neoplasm of overlapping sites of accessory sinuses C31.9 Malignant neoplasm of accessory sinus, unspecified C32.0 C32.3 Malignant neoplasm of glottis Malignant neoplasm of laryngeal cartilage C32.8 Malignant neoplasm of overlapping sites of larynx

9 C32.9 Malignant neoplasm of larynx, unspecified C33 Malignant neoplasm of trachea C34.01 Malignant neoplasm of right main bronchus C34.02 Malignant neoplasm of left main bronchus C34.11 Malignant neoplasm of upper lobe, right bronchus or lung C34.12 Malignant neoplasm of upper lobe, left bronchus or lung C34.2 Malignant neoplasm of middle lobe, bronchus or lung C34.31 Malignant neoplasm of lower lobe, right bronchus or lung C34.32 Malignant neoplasm of lower lobe, left bronchus or lung C34.81 Malignant neoplasm of overlapping sites of right bronchus and lung C34.82 Malignant neoplasm of overlapping sites of left bronchus and lung C34.91 Malignant neoplasm of unspecified part of right bronchus or lung C34.92 Malignant neoplasm of unspecified part of left bronchus or lung C37 Malignant neoplasm of thymus C38.0 C38.4 Malignant neoplasm of heart Malignant neoplasm of pleura C38.8 Malignant neoplasm of overlapping sites of heart, mediastinum and pleura C39.0 Malignant neoplasm of upper respiratory tract, part unspecified C39.9 Malignant neoplasm of lower respiratory tract, part unspecified C40.01 Malignant neoplasm of scapula and long bones of right upper limb C40.02 Malignant neoplasm of scapula and long bones of left upper limb C40.11 Malignant neoplasm of short bones of right upper limb C40.12 Malignant neoplasm of short bones of left upper limb C40.21 Malignant neoplasm of long bones of right lower limb C40.22 Malignant neoplasm of long bones of left lower limb C40.31 Malignant neoplasm of short bones of right lower limb C40.32 Malignant neoplasm of short bones of left lower limb C40.81 Malignant neoplasm of overlapping sites of bone and articular cartilage of right limb C40.82 Malignant neoplasm of overlapping sites of bone and articular cartilage of left limb C40.91 Malignant neoplasm of unspecified bones and articular cartilage of right limb C40.92 Malignant neoplasm of unspecified bones and articular cartilage of left limb C41.0 C41.4 Malignant neoplasm of bones of skull and face Malignant neoplasm of pelvic bones, sacrum and coccyx C43.0 Malignant melanoma of lip C43.11 Malignant melanoma of right eyelid, including canthus C43.12 Malignant melanoma of left eyelid, including canthus C43.21 Malignant melanoma of right ear and external auricular canal C43.22 Malignant melanoma of left ear and external auricular canal C43.30 Malignant melanoma of unspecified part of face C43.31 Malignant melanoma of nose

10 C43.39 Malignant melanoma of other parts of face C43.4 Malignant melanoma of scalp and neck C43.51 Malignant melanoma of anal skin C43.52 Malignant melanoma of skin of breast C43.59 Malignant melanoma of other part of trunk C43.61 Malignant melanoma of right upper limb, including shoulder C43.62 Malignant melanoma of left upper limb, including shoulder C43.71 Malignant melanoma of right lower limb, including hip C43.72 Malignant melanoma of left lower limb, including hip C43.8 Malignant melanoma of overlapping sites of skin C43.9 Malignant melanoma of skin, unspecified C44.00 C44.02 Unspecified malignant neoplasm of skin of lip Squamous cell carcinoma of skin of lip C44.09 Other specified malignant neoplasm of skin of lip C Unspecified malignant neoplasm of skin of right eyelid, including canthus C Unspecified malignant neoplasm of skin of left eyelid, including canthus C Basal cell carcinoma of skin of right eyelid, including canthus C Basal cell carcinoma of skin of left eyelid, including canthus C Squamous cell carcinoma of skin of right eyelid, including canthus C Squamous cell carcinoma of skin of left eyelid, including canthus C Other specified malignant neoplasm of skin of right eyelid, including canthus C Other specified malignant neoplasm of skin of left eyelid, including canthus C Unspecified malignant neoplasm of skin of right ear and external auricular canal C Unspecified malignant neoplasm of skin of left ear and external auricular canal C Basal cell carcinoma of skin of right ear and external auricular canal C Basal cell carcinoma of skin of left ear and external auricular canal C Squamous cell carcinoma of skin of right ear and external auricular canal C Squamous cell carcinoma of skin of left ear and external auricular canal C Other specified malignant neoplasm of skin of right ear and external auricular canal C Other specified malignant neoplasm of skin of left ear and external auricular canal C Unspecified malignant neoplasm of skin of unspecified part of face C Unspecified malignant neoplasm of skin of nose C Unspecified malignant neoplasm of skin of other parts of face C Basal cell carcinoma of skin of unspecified parts of face C Basal cell carcinoma of skin of nose C Basal cell carcinoma of skin of other parts of face C Squamous cell carcinoma of skin of unspecified parts of face C Squamous cell carcinoma of skin of nose C Squamous cell carcinoma of skin of other parts of face C Other specified malignant neoplasm of skin of unspecified parts of face C Other specified malignant neoplasm of skin of nose

11 C Other specified malignant neoplasm of skin of other parts of face C44.40 C44.42 Unspecified malignant neoplasm of skin of scalp and neck Squamous cell carcinoma of skin of scalp and neck C44.49 Other specified malignant neoplasm of skin of scalp and neck C Unspecified malignant neoplasm of anal skin C Unspecified malignant neoplasm of skin of breast C Unspecified malignant neoplasm of skin of other part of trunk C Basal cell carcinoma of anal skin C Basal cell carcinoma of skin of breast C Basal cell carcinoma of skin of other part of trunk C Squamous cell carcinoma of anal skin C Squamous cell carcinoma of skin of breast C Squamous cell carcinoma of skin of other part of trunk C Other specified malignant neoplasm of anal skin C Other specified malignant neoplasm of skin of breast C Other specified malignant neoplasm of skin of other part of trunk C Unspecified malignant neoplasm of skin of right upper limb, including shoulder C Unspecified malignant neoplasm of skin of left upper limb, including shoulder C Basal cell carcinoma of skin of right upper limb, including shoulder C Basal cell carcinoma of skin of left upper limb, including shoulder C Squamous cell carcinoma of skin of right upper limb, including shoulder C Squamous cell carcinoma of skin of left upper limb, including shoulder C Other specified malignant neoplasm of skin of right upper limb, including shoulder C Other specified malignant neoplasm of skin of left upper limb, including shoulder C Unspecified malignant neoplasm of skin of right lower limb, including hip C Unspecified malignant neoplasm of skin of left lower limb, including hip C Basal cell carcinoma of skin of right lower limb, including hip C Basal cell carcinoma of skin of left lower limb, including hip C Squamous cell carcinoma of skin of right lower limb, including hip C Squamous cell carcinoma of skin of left lower limb, including hip C Other specified malignant neoplasm of skin of right lower limb, including hip C Other specified malignant neoplasm of skin of left lower limb, including hip C44.80 C44.82 Unspecified malignant neoplasm of overlapping sites of skin Squamous cell carcinoma of overlapping sites of skin C44.89 Other specified malignant neoplasm of overlapping sites of skin C44.90 C44.92 Unspecified malignant neoplasm of skin, unspecified Squamous cell carcinoma of skin, unspecified C44.99 Other specified malignant neoplasm of skin, unspecified C45.0 C45.2 Mesothelioma of pleura Mesothelioma of pericardium C45.7 Mesothelioma of other sites

12 C45.9 Mesothelioma, unspecified C46.0 C46.4 Kaposi's sarcoma of skin Kaposi's sarcoma of gastrointestinal sites C46.51 Kaposi's sarcoma of right lung C46.52 Kaposi's sarcoma of left lung C46.7 Kaposi's sarcoma of other sites C46.9 Kaposi's sarcoma, unspecified C47.0 Malignant neoplasm of peripheral nerves of head, face and neck C47.11 Malignant neoplasm of peripheral nerves of right upper limb, including shoulder C47.12 Malignant neoplasm of peripheral nerves of left upper limb, including shoulder C47.21 Malignant neoplasm of peripheral nerves of right lower limb, including hip C47.22 Malignant neoplasm of peripheral nerves of left lower limb, including hip C47.3 C47.6 Malignant neoplasm of peripheral nerves of thorax Malignant neoplasm of peripheral nerves of trunk, unspecified C47.8 Malignant neoplasm of overlapping sites of peripheral nerves and autonomic nervous system C47.9 Malignant neoplasm of peripheral nerves and autonomic nervous system, unspecified C48.0 C48.2 Malignant neoplasm of retroperitoneum Malignant neoplasm of peritoneum, unspecified C48.8 Malignant neoplasm of overlapping sites of retroperitoneum and peritoneum C49.0 Malignant neoplasm of connective and soft tissue of head, face and neck C49.11 Malignant neoplasm of connective and soft tissue of right upper limb, including shoulder C49.12 Malignant neoplasm of connective and soft tissue of left upper limb, including shoulder C49.21 Malignant neoplasm of connective and soft tissue of right lower limb, including hip C49.22 Malignant neoplasm of connective and soft tissue of left lower limb, including hip C49.3 C49.6 Malignant neoplasm of connective and soft tissue of thorax Malignant neoplasm of connective and soft tissue of trunk, unspecified C49.8 Malignant neoplasm of overlapping sites of connective and soft tissue C49.9 Malignant neoplasm of connective and soft tissue, unspecified C4A.0 Merkel cell carcinoma of lip C4A.11 Merkel cell carcinoma of right eyelid, including canthus C4A.12 Merkel cell carcinoma of left eyelid, including canthus C4A.21 Merkel cell carcinoma of right ear and external auricular canal C4A.22 Merkel cell carcinoma of left ear and external auricular canal C4A.30 Merkel cell carcinoma of unspecified part of face C4A.31 Merkel cell carcinoma of nose C4A.39 Merkel cell carcinoma of other parts of face C4A.4 Merkel cell carcinoma of scalp and neck C4A.51 Merkel cell carcinoma of anal skin

13 C4A.52 Merkel cell carcinoma of skin of breast C4A.59 Merkel cell carcinoma of other part of trunk C4A.61 Merkel cell carcinoma of right upper limb, including shoulder C4A.62 Merkel cell carcinoma of left upper limb, including shoulder C4A.71 Merkel cell carcinoma of right lower limb, including hip C4A.72 Merkel cell carcinoma of left lower limb, including hip C4A.8 Merkel cell carcinoma of overlapping sites C Malignant neoplasm of nipple and areola, right female breast C Malignant neoplasm of nipple and areola, left female breast C Malignant neoplasm of nipple and areola, right male breast C Malignant neoplasm of nipple and areola, left male breast C Malignant neoplasm of central portion of right female breast C Malignant neoplasm of central portion of left female breast C Malignant neoplasm of central portion of right male breast C Malignant neoplasm of central portion of left male breast C Malignant neoplasm of upperinner quadrant of right female breast C Malignant neoplasm of upperinner quadrant of left female breast C Malignant neoplasm of upperinner quadrant of right male breast C Malignant neoplasm of upperinner quadrant of left male breast C Malignant neoplasm of lowerinner quadrant of right female breast C Malignant neoplasm of lowerinner quadrant of left female breast C Malignant neoplasm of lowerinner quadrant of right male breast C Malignant neoplasm of lowerinner quadrant of left male breast C Malignant neoplasm of upperouter quadrant of right female breast C Malignant neoplasm of upperouter quadrant of left female breast C Malignant neoplasm of upperouter quadrant of right male breast C Malignant neoplasm of upperouter quadrant of left male breast C Malignant neoplasm of lowerouter quadrant of right female breast C Malignant neoplasm of lowerouter quadrant of left female breast C Malignant neoplasm of lowerouter quadrant of right male breast C Malignant neoplasm of lowerouter quadrant of left male breast C Malignant neoplasm of axillary tail of right female breast C Malignant neoplasm of axillary tail of left female breast C Malignant neoplasm of axillary tail of right male breast C Malignant neoplasm of axillary tail of left male breast C Malignant neoplasm of overlapping sites of right female breast C Malignant neoplasm of overlapping sites of left female breast C Malignant neoplasm of overlapping sites of right male breast C Malignant neoplasm of overlapping sites of left male breast C Malignant neoplasm of unspecified site of right female breast C Malignant neoplasm of unspecified site of left female breast C Malignant neoplasm of unspecified site of right male breast

14 C Malignant neoplasm of unspecified site of left male breast C51.0 C51.2 Malignant neoplasm of labium majus Malignant neoplasm of clitoris C51.8 Malignant neoplasm of overlapping sites of vulva C51.9 Malignant neoplasm of vulva, unspecified C52 Malignant neoplasm of vagina C53.0 Malignant neoplasm of endocervix C53.1 Malignant neoplasm of exocervix C53.8 Malignant neoplasm of overlapping sites of cervix uteri C53.9 Malignant neoplasm of cervix uteri, unspecified C54.0 C54.3 Malignant neoplasm of isthmus uteri Malignant neoplasm of fundus uteri C54.8 Malignant neoplasm of overlapping sites of corpus uteri C55 Malignant neoplasm of uterus, part unspecified C56.1 Malignant neoplasm of right ovary C56.2 Malignant neoplasm of left ovary C57.01 Malignant neoplasm of right fallopian tube C57.02 Malignant neoplasm of left fallopian tube C57.11 Malignant neoplasm of right broad ligament C57.12 Malignant neoplasm of left broad ligament C57.21 Malignant neoplasm of right round ligament C57.22 Malignant neoplasm of left round ligament C57.3 Malignant neoplasm of parametrium C57.4 Malignant neoplasm of uterine adnexa, unspecified C57.7 C57.9 Malignant neoplasm of other specified female genital organs Malignant neoplasm of female genital organ, unspecified C58 Malignant neoplasm of placenta C60.0 C60.2 Malignant neoplasm of prepuce Malignant neoplasm of body of penis C60.8 Malignant neoplasm of overlapping sites of penis C60.9 Malignant neoplasm of penis, unspecified C61 Malignant neoplasm of prostate C62.01 Malignant neoplasm of undescended right testis C62.02 Malignant neoplasm of undescended left testis C62.11 Malignant neoplasm of descended right testis C62.12 Malignant neoplasm of descended left testis C62.91 Malignant neoplasm of right testis, unspecified whether descended or undescended C62.92 Malignant neoplasm of left testis, unspecified whether descended or undescended C63.01 Malignant neoplasm of right epididymis C63.02 Malignant neoplasm of left epididymis C63.11 Malignant neoplasm of right spermatic cord

15 C63.12 Malignant neoplasm of left spermatic cord C63.2 Malignant neoplasm of scrotum C63.7 C63.9 Malignant neoplasm of other specified male genital organs Malignant neoplasm of male genital organ, unspecified C64.1 Malignant neoplasm of right kidney, except renal pelvis C64.2 Malignant neoplasm of left kidney, except renal pelvis C65.1 Malignant neoplasm of right renal pelvis C65.2 Malignant neoplasm of left renal pelvis C66.1 Malignant neoplasm of right ureter C66.2 Malignant neoplasm of left ureter C67.0 C67.9 Malignant neoplasm of trigone of bladder Malignant neoplasm of bladder, unspecified C68.0 Malignant neoplasm of urethra C68.1 Malignant neoplasm of paraurethral glands C68.8 Malignant neoplasm of overlapping sites of urinary organs C68.9 Malignant neoplasm of urinary organ, unspecified C69.01 Malignant neoplasm of right conjunctiva C69.02 Malignant neoplasm of left conjunctiva C69.11 Malignant neoplasm of right cornea C69.12 Malignant neoplasm of left cornea C69.21 Malignant neoplasm of right retina C69.22 Malignant neoplasm of left retina C69.31 Malignant neoplasm of right choroid C69.32 Malignant neoplasm of left choroid C69.41 Malignant neoplasm of right ciliary body C69.42 Malignant neoplasm of left ciliary body C69.51 Malignant neoplasm of right lacrimal gland and duct C69.52 Malignant neoplasm of left lacrimal gland and duct C69.61 Malignant neoplasm of right orbit C69.62 Malignant neoplasm of left orbit C69.81 Malignant neoplasm of overlapping sites of right eye and adnexa C69.82 Malignant neoplasm of overlapping sites of left eye and adnexa C69.91 Malignant neoplasm of unspecified site of right eye C69.92 Malignant neoplasm of unspecified site of left eye C70.0 Malignant neoplasm of cerebral meninges C70.1 Malignant neoplasm of spinal meninges C71.0 C71.9 Malignant neoplasm of cerebrum, except lobes and ventricles Malignant neoplasm of brain, unspecified C72.0 Malignant neoplasm of spinal cord C72.1 Malignant neoplasm of cauda equina C72.21 Malignant neoplasm of right olfactory nerve C72.22 Malignant neoplasm of left olfactory nerve

16 C72.31 Malignant neoplasm of right optic nerve C72.32 Malignant neoplasm of left optic nerve C72.41 Malignant neoplasm of right acoustic nerve C72.42 Malignant neoplasm of left acoustic nerve C72.50 Malignant neoplasm of unspecified cranial nerve C72.59 Malignant neoplasm of other cranial nerves C72.9 Malignant neoplasm of central nervous system, unspecified C73 Malignant neoplasm of thyroid gland C74.01 Malignant neoplasm of cortex of right adrenal gland C74.02 Malignant neoplasm of cortex of left adrenal gland C74.11 Malignant neoplasm of medulla of right adrenal gland C74.12 Malignant neoplasm of medulla of left adrenal gland C74.91 Malignant neoplasm of unspecified part of right adrenal gland C74.92 Malignant neoplasm of unspecified part of left adrenal gland C75.0 C75.5 Malignant neoplasm of parathyroid gland Malignant neoplasm of aortic body and other paraganglia C75.8 Malignant neoplasm with pluriglandular involvement, unspecified C75.9 Malignant neoplasm of endocrine gland, unspecified C76.0 C76.3 Malignant neoplasm of head, face and neck Malignant neoplasm of pelvis C76.41 Malignant neoplasm of right upper limb C76.42 Malignant neoplasm of left upper limb C76.51 Malignant neoplasm of right lower limb C76.52 Malignant neoplasm of left lower limb C76.8 Malignant neoplasm of other specified illdefined sites C77.0 C77.5 Secondary and unspecified malignant neoplasm of lymph nodes of head, face and neck Secondary and unspecified malignant neoplasm of intrapelvic lymph nodes C77.8 Secondary and unspecified malignant neoplasm of lymph nodes of multiple regions C77.9 Secondary and unspecified malignant neoplasm of lymph node, unspecified C78.01 Secondary malignant neoplasm of right lung C78.02 Secondary malignant neoplasm of left lung C78.1 Secondary malignant neoplasm of mediastinum C78.2 Secondary malignant neoplasm of pleura C78.39 Secondary malignant neoplasm of other respiratory organs C78.4 C78.7 Secondary malignant neoplasm of small intestine Secondary malignant neoplasm of liver and intrahepatic bile duct C78.89 Secondary malignant neoplasm of other digestive organs C79.01 Secondary malignant neoplasm of right kidney and renal pelvis C79.02 Secondary malignant neoplasm of left kidney and renal pelvis C79.10 Secondary malignant neoplasm of unspecified urinary organs C79.11 Secondary malignant neoplasm of bladder

17 C79.19 Secondary malignant neoplasm of other urinary organs C79.2 Secondary malignant neoplasm of skin C79.31 Secondary malignant neoplasm of brain C79.32 Secondary malignant neoplasm of cerebral meninges C79.49 Secondary malignant neoplasm of other parts of nervous system C79.51 Secondary malignant neoplasm of bone C79.52 Secondary malignant neoplasm of bone marrow C79.61 Secondary malignant neoplasm of right ovary C79.62 Secondary malignant neoplasm of left ovary C79.71 Secondary malignant neoplasm of right adrenal gland C79.72 Secondary malignant neoplasm of left adrenal gland C79.81 Secondary malignant neoplasm of breast C79.82 Secondary malignant neoplasm of genital organs C79.89 Secondary malignant neoplasm of other specified sites C7A.00 Malignant carcinoid tumor of unspecified site C7A.010 Malignant carcinoid tumor of the duodenum C7A.011 Malignant carcinoid tumor of the jejunum C7A.012 Malignant carcinoid tumor of the ileum C7A.019 Malignant carcinoid tumor of the small intestine, unspecified portion C7A.020 Malignant carcinoid tumor of the appendix C7A.021 Malignant carcinoid tumor of the cecum C7A.022 Malignant carcinoid tumor of the ascending colon C7A.023 Malignant carcinoid tumor of the transverse colon C7A.024 Malignant carcinoid tumor of the descending colon C7A.025 Malignant carcinoid tumor of the sigmoid colon C7A.026 Malignant carcinoid tumor of the rectum C7A.029 Malignant carcinoid tumor of the large intestine, unspecified portion C7A.090 Malignant carcinoid tumor of the bronchus and lung C7A.091 Malignant carcinoid tumor of the thymus C7A.092 Malignant carcinoid tumor of the stomach C7A.093 Malignant carcinoid tumor of the kidney C7A.094 Malignant carcinoid tumor of the foregut NOS C7A.095 Malignant carcinoid tumor of the midgut NOS C7A.096 Malignant carcinoid tumor of the hindgut NOS C7A.098 Malignant carcinoid tumors of other sites C7A.1 Malignant poorly differentiated neuroendocrine tumors C7A.8 Other malignant neuroendocrine tumors C80.0 Disseminated malignant neoplasm, unspecified C80.1 Malignant (primary) neoplasm, unspecified C81.01 C81.09 Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of head, face, and neck Nodular lymphocyte predominant Hodgkin lymphoma, extranodal and solid organ sites

18 C81.11 C81.19 C81.21 C81.29 C81.31 C81.39 C81.41 C81.49 C81.71 C81.79 C81.91 C81.99 C82.01 C82.09 C82.11 C82.19 C82.21 C82.29 C82.31 C82.39 C82.41 C82.49 C82.51 C82.59 C82.61 C82.69 C82.81 C82.89 C82.91 C82.99 C83.01 C83.09 C83.11 C83.19 C83.31 C83.39 C83.51 C83.59 C83.71 C83.79 Nodular sclerosis classical Hodgkin lymphoma, lymph nodes of head, face, and neck Nodular sclerosis classical Hodgkin lymphoma, extranodal and solid organ sites Mixed cellularity classical Hodgkin lymphoma, lymph nodes of head, face, and neck Mixed cellularity classical Hodgkin lymphoma, extranodal and solid organ sites Lymphocyte depleted classical Hodgkin lymphoma, lymph nodes of head, face, and neck Lymphocyte depleted classical Hodgkin lymphoma, extranodal and solid organ sites Lymphocyterich classical Hodgkin lymphoma, lymph nodes of head, face, and neck Lymphocyterich classical Hodgkin lymphoma, extranodal and solid organ sites Other classical Hodgkin lymphoma, lymph nodes of head, face, and neck Other classical Hodgkin lymphoma, extranodal and solid organ sites Hodgkin lymphoma, unspecified, lymph nodes of head, face, and neck Hodgkin lymphoma, unspecified, extranodal and solid organ sites Follicular lymphoma grade I, lymph nodes of head, face, and neck Follicular lymphoma grade I, extranodal and solid organ sites Follicular lymphoma grade II, lymph nodes of head, face, and neck Follicular lymphoma grade II, extranodal and solid organ sites Follicular lymphoma grade III, unspecified, lymph nodes of head, face, and neck Follicular lymphoma grade III, unspecified, extranodal and solid organ sites Follicular lymphoma grade IIIa, lymph nodes of head, face, and neck Follicular lymphoma grade IIIa, extranodal and solid organ sites Follicular lymphoma grade IIIb, lymph nodes of head, face, and neck Follicular lymphoma grade IIIb, extranodal and solid organ sites Diffuse follicle center lymphoma, lymph nodes of head, face, and neck Diffuse follicle center lymphoma, extranodal and solid organ sites Cutaneous follicle center lymphoma, lymph nodes of head, face, and neck Cutaneous follicle center lymphoma, extranodal and solid organ sites Other types of follicular lymphoma, lymph nodes of head, face, and neck Other types of follicular lymphoma, extranodal and solid organ sites Follicular lymphoma, unspecified, lymph nodes of head, face, and neck Follicular lymphoma, unspecified, extranodal and solid organ sites Small cell Bcell lymphoma, lymph nodes of head, face, and neck Small cell B cell lymphoma, extranodal and solid organ sites Mantle cell lymphoma, lymph nodes of head, face, and neck Mantle cell lymphoma, extranodal and solid organ sites Diffuse large Bcell lymphoma, lymph nodes of head, face, and neck Diffuse large Bcell lymphoma, extranodal and solid organ sites Lymphoblastic (diffuse) lymphoma, lymph nodes of head, face, and neck Lymphoblastic (diffuse) lymphoma, extranodal and solid organ sites Burkitt lymphoma, lymph nodes of head, face, and neck Burkitt lymphoma, extranodal and solid organ sites

19 C83.81 C83.89 C83.91 C83.99 C84.01 C84.09 C84.11 C84.19 C84.41 C84.49 C84.61 C84.69 C84.71 C84.79 C84.91 C84.99 C84.A1 C84.A2 C84.A3 C84.A4 C84.A5 C84.A6 C84.A7 C84.A8 C84.A9 C84.Z1 C84.Z2 C84.Z3 C84.Z4 C84.Z5 C84.Z6 C84.Z7 C84.Z8 C84.Z9 C85.11 C85.19 Other nonfollicular lymphoma, lymph nodes of head, face, and neck Other nonfollicular lymphoma, extranodal and solid organ sites Nonfollicular (diffuse) lymphoma, unspecified, lymph nodes of head, face, and neck Nonfollicular (diffuse) lymphoma, unspecified, extranodal and solid organ sites Mycosis fungoides, lymph nodes of head, face, and neck Mycosis fungoides, extranodal and solid organ sites Sezary disease, lymph nodes of head, face, and neck Sezary disease, extranodal and solid organ sites Peripheral Tcell lymphoma, not classified, lymph nodes of head, face, and neck Peripheral Tcell lymphoma, not classified, extranodal and solid organ sites Anaplastic large cell lymphoma, ALKpositive, lymph nodes of head, face, and neck Anaplastic large cell lymphoma, ALKpositive, extranodal and solid organ sites Anaplastic large cell lymphoma, ALKnegative, lymph nodes of head, face, and neck Anaplastic large cell lymphoma, ALKnegative, extranodal and solid organ sites Mature T/NKcell lymphomas, unspecified, lymph nodes of head, face, and neck Mature T/NKcell lymphomas, unspecified, extranodal and solid organ sites Cutaneous Tcell lymphoma, unspecified lymph nodes of head, face, and neck Cutaneous Tcell lymphoma, unspecified, intrathoracic lymph nodes Cutaneous Tcell lymphoma, unspecified, intraabdominal lymph nodes Cutaneous Tcell lymphoma, unspecified, lymph nodes of axilla and upper limb Cutaneous Tcell lymphoma, unspecified, lymph nodes of inguinal region and lower limb Cutaneous Tcell lymphoma, unspecified, intrapelvic lymph nodes Cutaneous Tcell lymphoma, unspecified, spleen Cutaneous Tcell lymphoma, unspecified, lymph nodes of multiple sites Cutaneous Tcell lymphoma, unspecified, extranodal and solid organ sites Other mature T/NKcell lymphomas, lymph nodes of head, face, and neck Other mature T/NKcell lymphomas, intrathoracic lymph nodes Other mature T/NKcell lymphomas, intraabdominal lymph nodes Other mature T/NKcell lymphomas, lymph nodes of axilla and upper limb Other mature T/NKcell lymphomas, lymph nodes of inguinal region and lower limb Other mature T/NKcell lymphomas, intrapelvic lymph nodes Other mature T/NKcell lymphomas, spleen Other mature T/NKcell lymphomas, lymph nodes of multiple sites Other mature T/NKcell lymphomas, extranodal and solid organ sites Unspecified Bcell lymphoma, lymph nodes of head, face, and neck Unspecified Bcell lymphoma, extranodal and solid organ sites

20 C85.21 C85.29 C85.81 C85.89 Mediastinal (thymic) large Bcell lymphoma, lymph nodes of head, face, and neck Mediastinal (thymic) large Bcell lymphoma, extranodal and solid organ sites Other specified types of nonhodgkin lymphoma, lymph nodes of head, face, and neck Other specified types of nonhodgkin lymphoma, extranodal and solid organ sites NonHodgkin lymphoma, unspecified, lymph nodes of head, face, and neck NonHodgkin lymphoma, unspecified, extranodal and solid organ sites Extranodal NK/Tcell lymphoma, nasal type Primary cutaneous CD30positive C85.91 C85.99 C86.0 C86.6 Tcell proliferations C88.2 C88.4 Heavy chain disease Extranodal marginal zone Bcell lymphoma of mucosaassociated lymphoid tissue [MALTlymphoma] C88.8 Other malignant immunoproliferative diseases C90.00 C90.02 Multiple myeloma not having achieved remission Multiple myeloma in relapse C90.10 Plasma cell leukemia not having achieved remission Plasma cell leukemia in C90.12 relapse C90.20 Extramedullary plasmacytoma not having achieved remission Extramedullary C90.22 plasmacytoma in relapse C90.30 Solitary plasmacytoma not having achieved remission Solitary plasmacytoma in C90.32 relapse C91.00 Acute lymphoblastic leukemia not having achieved remission Acute C91.02 lymphoblastic leukemia, in relapse C91.10 Chronic lymphocytic leukemia of Bcell type not having achieved remission C91.12 Chronic lymphocytic leukemia of Bcell type in relapse C91.30 Prolymphocytic leukemia of Bcell type not having achieved remission C91.32 Prolymphocytic leukemia of Bcell type, in relapse C91.40 Hairy cell leukemia not having achieved remission Hairy cell leukemia, in C91.42 relapse C91.50 Adult Tcell lymphoma/leukemia (HTLV1associated) not having achieved C91.52 remission Adult Tcell lymphoma/leukemia (HTLV1associated), in relapse C91.60 Prolymphocytic leukemia of Tcell type not having achieved remission C91.62 Prolymphocytic leukemia of Tcell type, in relapse C91.90 Lymphoid leukemia, unspecified not having achieved remission Lymphoid C91.92 leukemia, unspecified, in relapse C91.A0 Mature Bcell leukemia Burkitttype not having achieved remission C91.A1 Mature Bcell leukemia Burkitttype, in remission C91.A2 Mature Bcell leukemia Burkitttype, in relapse C91.Z0 Other lymphoid leukemia not having achieved remission C91.Z1 Other lymphoid leukemia, in remission C91.Z2 Other lymphoid leukemia, in relapse C92.00 Acute myeloblastic leukemia, not having achieved remission Acute myeloblastic C92.02 leukemia, in relapse

21 C92.10 C92.12 Chronic myeloid leukemia, BCR/ABLpositive, not having achieved remission Chronic myeloid leukemia, BCR/ABLpositive, in relapse C92.20 C92.22 Atypical chronic myeloid leukemia, BCR/ABLnegative, not having achieved remission Atypical chronic myeloid leukemia, BCR/ABLnegative, in relapse C92.30 C92.32 Myeloid sarcoma, not having achieved remission Myeloid sarcoma, in relapse C92.40 C92.42 Acute promyelocytic leukemia, not having achieved remission Acute promyelocytic leukemia, in relapse C92.50 C92.52 Acute myelomonocytic leukemia, not having achieved remission Acute myelomonocytic leukemia, in relapse C92.60 C92.62 Acute myeloid leukemia with 11q23abnormality not having achieved remission Acute myeloid leukemia with 11q23abnormality in relapse C92.90 C92.92 Myeloid leukemia, unspecified, not having achieved remission Myeloid leukemia, unspecified in relapse C92.A0 Acute myeloid leukemia with multilineage dysplasia, not having achieved remission C92.A1 Acute myeloid leukemia with multilineage dysplasia, in remission C92.A2 Acute myeloid leukemia with multilineage dysplasia, in relapse C92.Z0 Other myeloid leukemia not having achieved remission C92.Z1 Other myeloid leukemia, in remission C92.Z2 Other myeloid leukemia, in relapse C93.00 C93.02 Acute monoblastic/monocytic leukemia, not having achieved remission Acute monoblastic/monocytic leukemia, in relapse C93.10 C93.12 Chronic myelomonocytic leukemia not having achieved remission Chronic myelomonocytic leukemia, in relapse C93.30 C93.32 Juvenile myelomonocytic leukemia, not having achieved remission Juvenile myelomonocytic leukemia, in relapse C93.90 C93.92 Monocytic leukemia, unspecified, not having achieved remission Monocytic leukemia, unspecified in relapse C93.Z0 Other monocytic leukemia, not having achieved remission C93.Z1 Other monocytic leukemia, in remission C93.Z2 Other monocytic leukemia, in relapse C94.00 C94.02 Acute erythroid leukemia, not having achieved remission Acute erythroid leukemia, in relapse C94.20 C94.22 Acute megakaryoblastic leukemia not having achieved remission Acute megakaryoblastic leukemia, in relapse C94.30 C94.32 Mast cell leukemia not having achieved remission Mast cell leukemia, in relapse C94.40 C94.42 Acute panmyelosis with myelofibrosis not having achieved remission Acute panmyelosis with myelofibrosis, in relapse C94.6 Myelodysplastic disease, not classified C94.80 C94.82 Other specified leukemias not having achieved remission Other specified leukemias, in relapse

22 C95.00 C95.02 Acute leukemia of unspecified cell type not having achieved remission Acute leukemia of unspecified cell type, in relapse C95.10 C95.12 Chronic leukemia of unspecified cell type not having achieved remission Chronic leukemia of unspecified cell type, in relapse C95.90 C95.92 Leukemia, unspecified not having achieved remission Leukemia, unspecified, in relapse C96.0 Multifocal and multisystemic (disseminated) Langerhanscell histiocytosis C96.2 Malignant mast cell tumor C96.4 Sarcoma of dendritic cells (accessory cells) C96.9 Malignant neoplasm of lymphoid, hematopoietic and related tissue, unspecified C96.A Histiocytic sarcoma C96.Z Other specified malignant neoplasms of lymphoid, hematopoietic and related tissue D00.01 D00.08 Carcinoma in situ of labial mucosa and vermilion border Carcinoma in situ of pharynx D00.1 Carcinoma in situ of esophagus D00.2 Carcinoma in situ of stomach D01.0 D01.3 Carcinoma in situ of colon Carcinoma in situ of anus and anal canal D01.49 Carcinoma in situ of other parts of intestine D01.5 Carcinoma in situ of liver, gallbladder and bile ducts D01.7 Carcinoma in situ of other specified digestive organs D01.9 Carcinoma in situ of digestive organ, unspecified D02.0 Carcinoma in situ of larynx D02.1 Carcinoma in situ of trachea D02.21 Carcinoma in situ of right bronchus and lung D02.22 Carcinoma in situ of left bronchus and lung D02.3 Carcinoma in situ of other parts of respiratory system D02.4 Carcinoma in situ of respiratory system, unspecified D03.0 Melanoma in situ of lip D03.11 Melanoma in situ of right eyelid, including canthus D03.12 Melanoma in situ of left eyelid, including canthus D03.21 Melanoma in situ of right ear and external auricular canal D03.22 Melanoma in situ of left ear and external auricular canal D03.30 Melanoma in situ of unspecified part of face D03.39 Melanoma in situ of other parts of face D03.4 Melanoma in situ of scalp and neck D03.51 Melanoma in situ of anal skin D03.52 Melanoma in situ of breast (skin) (soft tissue) D03.59 Melanoma in situ of other part of trunk D03.61 Melanoma in situ of right upper limb, including shoulder D03.62 Melanoma in situ of left upper limb, including shoulder

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