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1 Francesco Cerutti Born on June 18, 1984 in Torino, Italy University of Torino Department of Animal production, Epidemiology and Ecology Via Leonardo da Vinci, Grugliasco (TO), Italy Phone: (+39) Fax: (+39) Education January present PhD Candidate, School of Veterinary Sciences, Program in Basic Sciences and Veterinary Biotechnology, Universitá degli Studi di Torino, Torino, Italy M.S. in Medical Biotechnology, Faculty of Medicine and Surgery, Universitá degli Studi di Torino, Torino, Italy. Title obtained on September 22nd 2008 with a final grade of 110/110 Title of thesis: Pathogenesis of diserythropoiesis in malarial anemia. Modulation of the proliferation of erythroid precursors by malarial pigment (haemozoin) and 4 - hydroxinonenal. Supervisor: prof. Paolo Arese BS in Medical Biotechnology, Faculty of Biotechnology, Universitá degli Studi di Torino, Torino, Italy. Title obtained on July 21st 2006 with a final grade of 101/110 Title of thesis: Real Time Polymerase Chain Reaction in diagnosis for Hepatitis C Virus infections. Supervisor: Dr. Valeria Ghisetti Scientific High School Carlo Cattaneo in Torino, Italy Scientific Degree with final grade of 100/100. Additional educational experience 7-8 October 2010: Perl for biologists, CINECA, Bologna, Italy 27 August 1 September 2010: Italian Workshop on phylogenetic methods and applications, Abbiategrasso (MI), Italy 31 August 3 September 2009: Italian Workshop on phylogenetic methods and applications, Asti, Italy 29 June 3 July 2009: XVI BioStAt 2009 International advanced school on statistical inference in biology and human sciences 8-11 June 2009: 4 th Summer school in optimization by evolutionary algorithms Porquerolles island, Hyéres, France October 2008: Course in Base Laboratory for Tropical Countries Ospedale "Sacro Cuore Don Calabria", Negrar (VR), Italy.

2 Francesco Cerutti 2 Professional experience October May 2010: Fellowship at the University of Wisconsin Madison, working with Prof. Tony L. Goldberg on molecular and computational approaches to the epidemiology and ecology of West Nile virus, Culex flavivirus and Porcine Reproductive and Respiratory Syndrome virus. November December 2008; August 2009: Volunteer work at the clinical laboratory of the St. John Hospital, Lugarawa, Ludewa District, Tanzania, devoted in teaching the laboratory students, in laboratory maintenance and arranging laboratory equipments. October May 2008; January 2009-May 2009; October-December 2010: Teaching assistant of the laboratory of Bioinformatics for the Biotechnology students, under the supervision of Dr. Mario Giacobini, Principal Investigator of the Computational Biology Unit, Molecular Biotechnology Centre, University of Torino. The program includes an introduction to MS Windows Operating System, MS Office Pack, UNIX and Linux operating systems and PERL Programming. Academic Year : Stage with Prof. Paolo Arese, Department of Biochemistry, Biology and Genetics, University of Torino. Topics: 1) Plasmodium falciparum response to oxidative stress; 2)pathogenesis of the inefficient erythropoiesis during malarial anemia. Academic Years and : Stage with Dr. Valeria Ghisetti at Microbiology Laboratory, Molinette Hospital, Torino, Italy, where I was introduced to the PCR-based techniques, sequencing and sequence data analysis, working on Hepatitis B Virus (HBV), Hepatitis C Virus (HCV) and Herpes Viruses. Personal skills and competences Language skills English Reading: very good Writing: very good Oral: very good French Reading: good Writing: good Oral: good Kiswahili Reading: basic knowledge Writing: basic knowledge Oral: basic knowledge Spanish Reading: basic knowledge Writing: basic knowledge Oral: basic knowledge

3 Francesco Cerutti 3 Computing skills Optimal knowledge of Window OS, Mac OS, and Linux Operating System, MS Office, Internet browsers. Good knowledge in LaTeX, PERL, Python, R software and bioinformatics softwares for sequence analysis and phylogenetics (Mesquite, PAUP*, Mega4, MrBayes, BEAST). Social skills During my experience in Scout movement I have been involved several times in workgroups and I am used to work with people, despite differences of points of view. Publications F. Cerutti, L. Bertolotti, T. Goldberg, and M. Giacobini, Taxon ordering in phylogenetic trees: a workbench test, BMC Bioinformatics, vol. 12, no. 1, p. 58, 2011 C. M. Newman, F. Cerutti, T. K. Anderson, G. L. Hamer, E. D. Walker, U. D. Kitron, M. O. Ruiz, J. D. Brawn, and T. L. Goldberg, Culex flavivirus and West Nile virus mosquito co-infection and positive ecological association in Chicago, USA, Vector-Borne and Zoonotic Diseases, vol. in press, pp. 1 10, 2011 F. Cerutti, L. Bertolotti, T. L. Goldberg, and M. Giacobini, Taxon order in phylogenetic trees by means of population evolutionary algorithms, Biodata Mining, p. submitted, 2011 F. Cerutti, L. Bertolotti, T. L. Goldberg, and M. Giacobini, Adding Vertical Meaning to Phylogenetic Trees by Artificial Evolution, Proceedings of the 10th European Conference on Artificial Life (ECAL 2009), vol. LNCS/LNAI, no. 5777, 5778, p. in press, 2011 F. Cerutti, L. Bertolotti, T. Goldberg, and M. Giacobini, Investigating Populational Evolutionary Algorithms to Add Vertical Meaning in Phylogenetic Trees, in Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics (C. Pizzuti, M. D. Ritchie, and M. Giacobini, eds.), vol of Lecture Notes in Computer Science, (Berlin, Heidelberg), pp , Springer Berlin Heidelberg, 2010 T. Allice, F. Cerutti, F. Pittaluga, S. Varetto, A. Franchello, M. Salizzoni, and V. Ghisetti, Evaluation of a novel real-time PCR system for cytomegalovirus DNA quantitation on whole blood and correlation with pp65-antigen test in guiding pre-emptive antiviral treatment., Journal of virological methods, vol. 148, pp. 9 16, Mar T. Allice, F. Cerutti, F. Pittaluga, S. Varetto, S. Gabella, A. Marzano, A. Franchello, and V. Ghisetti, Comparison of the Cobas Ampliprep/Cobas TaqMan HBV Test versus the Cobas Amplicor HBV monitor for HBV-DNA detection and quantification during antiviral therapy., The new microbiologica, vol. 31, pp , Jan F. Pittaluga, T. Allice, M. L. Abate, A. Ciancio, F. Cerutti, S. Varetto, G. Colucci, A. Smedile, and V. Ghisetti, Clinical evaluation of the COBAS Ampliprep/COBAS TaqMan for HCV RNA quantitation in comparison with the branched-dna assay., Journal of medical virology, vol. 80, pp , Feb T. Allice, F. Cerutti, F. Pittaluga, S. Varetto, S. Gabella, A. Franchello, M. Rinaldi, and V. Ghisetti, Whole blood real-time PCR for cytomegalovirus DNA quantification: analysis of PCR data and pp65 antigen test in a cohort of solid-organ transplant recipients, International Journal of Antimicrobial Agents, vol. 29, no. supplement 2, pp. S148 S149, 2007 T. Allice, F. Cerutti, F. Pittaluga, S. Varetto, S. Gabella, A. Marzano, A. Franchello, G. Colucci, and V. Ghisetti, COBAS AmpliPrep-COBAS TaqMan hepatitis B virus (HBV) test: a novel automated realtime PCR assay for quantification of HBV DNA in plasma., Journal of clinical microbiology, vol. 45, pp , Mar. 2007

4 Francesco Cerutti 4 Communications in international conferences Goldberg T, Kitron U, Ruiz M, Walker E, Brawn J, Hamer G, Anderson T, Chaves L, Bertolotti L, Amore G, Cerutti F, Krebs B, Newman C. Transmission, amplification and evolution of West Nile virus in chicago, USA.American Society of Tropical Medicine and Hygiene 59 th Annual Meeting Atlanta, GA, USA, November 3 7, 2010 (oral presentation). Newman C, Cerutti F, Anderson T, Hamer G, Walker E, Kitron U, Ruiz M, Brawn J, Goldberg T. Culex flavivirus enhances West Nile virus mosquito infection, Chicago USA. American Society of Tropical Medicine and Hygiene 59 th Annual Meeting Atlanta, GA, USA, November 3 7, 2010 (poster presentation). Cerutti F, Bertolotti L, Goldberg TL, Giacobini M. Vertical Meaning in Phylogenetic Trees: a Workbench Test. 10 th International Conference on Molecular Epidemiology and Evolutionary Genetics of Infectious Diseases Amsterdam, the Netherlands, 3 5 November, 2010 (oral presentation). Goldberg T, Kitron U, Ruiz M, Walker E, Brawn J, Hamer G, Anderson T, Cerutti F, Bertolotti L, Amore G, Newman C. Urbanization and West Nile virus transmission in Chicago, USA. EcoHealth 2010 Conference London, UK, August, 2010 (oral presentation). Bertolotti L, Bisanzio D, Cerutti F, Mosca A, Balbo L, Vazquez-Prokopec GM, Kitron U, Giacobini M. Spatial analysis and molecular studies of mosquito vectors and West Nile Virus in Piedmont, Northern Italy. International Conference EDEN 2010 Le Corum, Montpellier, France, May 10 12, 2010 (poster presentation). Cerutti F, Bertolotti L, Goldberg TL, Giacobini M. Investigating Populational Evolutionary Algorithms to Add Vertical Meaning in Phylogenetic Trees. EvoBio 2010 Istanbul, Turkey, April 7 9, 2010 (poster presentation and full article). Cerutti F, Bertolotti L, Goldberg TL, Giacobini M. Adding Vertical Meaning to Phylogenetic Trees by Artificial Evolution. Understanding emergence of infectious diseases: focus on new experimental and theoretical approaches to virus evolution Roscoff, France, September 26 30, 2009 (poster presentation). Cerutti F, Bertolotti L, Goldberg TL, Giacobini M. Adding Vertical Meaning to Phylogenetic Trees by Artificial Evolution. Advances in Artificial life: ECAL th European Conference on the Simulation and Synthesis of Living Systems Budapest, Hungary, September 2009 (poster presentation and full article). Cerutti F, Bertolotti L, Goldberg TL, Giacobini M. Artificial Evolution to Add Vertical Meaning to Phylogenetic Trees. 4 th Summer school in optimization by evolutionary algorithms Porquerolles island, Hyéres, France, June 8 11, 2009 (poster presentation). Cerutti F, Bertolotti L, Ghisetti V, Giacobini M. West Nile Virus emergence in Piedmont, Northern Italy: from molecular to computational approach. 5 th European Mosquito Control Association Workshop, Turin, Italy, March 9 13, 2009 (poster presentation). Cerutti F, Bertolotti L, Ghisetti V, Giacobini M. West Nile Virus emergence in Piedmont, Northern Italy: from molecular to computational approach. 3 rd EWDA Student Workshop 2009, Veyrier-du-Lac, France, March 19 22, 2009 (poster presentation). Allice T, Cerutti F, Pittaluga F, Varetto S, Gabella S, Franchello A, Rinaldi M, Ghisetti V. Whole blood real-time PCR for cytomegalovirus DNA quantification: analysis of PCR data and pp65 antigen test in a cohort of solid-organ transplant recipients. 17 th European Congress of Clinical Microbiology and Infectious Diseases, Munich, Germany, March 31 April 3, 2007 (poster presentation).

5 Francesco Cerutti 5 Allice T, Gabella S, Varetto S, Pittaluga F, Smedile A, Cerutti F, Ghisetti V. Real-time polymerase chain reaction and HCV RNA quantification: comparison of Cobas Ampliprep-Cobas TaqMan and branched DNA technology. 16 th European Congress of Clinical Microbiology and Infectious Diseases, Nice, France, April 1 4, 2006 (poster presentation). Communications in national conferences Cerutti F, Giacobini M, Goldberg TL, Bertolotti L. Molecular epidemiology: improving the interpretation of phylogenetic trees by artificial evolution. 5 th Workshop Italiano di Epidemiologia Veterinaria (5 th Italian Workshop of Veterinary Epidemiology) Torino, Italy, December 10 11, 2009 (submitted). Cerutti F, Allice T, Gabella S, Pittaluga F, Varetto S, Giliberto G, Martelli S, Smedile A, Ghisetti V, Marchiaro G. Real-time PCR per la ricerca di HCV RNA nel plasma. 30 th AMCLI National Congress Torino, Italy, September 2006 (poster presentation). De Masi A, Cerutti F, Allice T, Pittaluga F, Varetto S, Martelli S, Giliberto G, Gabella S, Marzano A, Colucci G, Ghisetti V, Marchiaro G. Quantizzazione di HBV-DNA in Real-time PCR: Cobas Ampliprepł/Cobas Taqmanł HBV test. 30ą AMCLI National Congress Torino, Italy, September 2006 (poster presentation). Last updated: March 8, 2011

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