Pen Injectors to 2022



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Greystone Research Associates 1+603-595-4340 January 2015 Pen Injectors to 2022 Devices, Drugs, Combination Products Contents A Comprehensive Market Analysis Report Scope & Overview 2 Table of Contents 3 Report Summary 4 Methodology 5 How to Order 6

2 The Evolving Injectable Drug Landscape The administration of therapeutic drugs via injection is an indispensable delivery method for numerous drugs critical to patient health and well-being. Now this segment is evolving in response to changing patient populations, new classes of powerful therapeutic drugs and healthcare administration initiatives. Population demographics and efforts by managed care providers to control healthcare costs are driving the growth in drug self-administration, particularly for chronic conditions, introducing a new class of naïve users to parenteral drug delivery. The value we provide to our clients and subscribers is best illustrated by our ability to consistently provide strategic direction and market knowledge that contributes to their tactical and strategic decision process. Tailored Research Market-driven Product Strategies As technology and products evolve, the level of precision in management decisions required to enable effective company performance is increasing. Such precision cannot be achieved without timely and accurate data about the company's macroscopic operating environment. The information that you and your management team require to execute your business and market strategies is unique to your organization and business model. This is why - in addition to the multi-client reports you will find on our site - we offer client-specific research services that start with customer-defined needs and culminate in assessments and analysis that answer the questions that represent risk to your business strategy. To discuss Greystone's Customer Defined Research services, we invite you to contact us. A longer life span is expected to translate to a growing number of patients diagnosed with chronic conditions. To counteract the financial and medical infrastructure implications of this trend, pressure from the public sector and managed care organizations will place a premium on therapeutic self-administration, an expectation that is creating an increased interest in routes of administration that are patient-friendly and cost-effective. Pharma company decision makers have come to the realization that for many products, success no longer only depends on the medication itself but also on achieving a consumer-compatible form of packaging and application.

Table of Contents Executive Summary 2 Injectable Drug Sector Market Dynamics The Injectable Drug Ecosystem Drug Classes, Indications and Demand What s Driving the Growth in Pen Injectors Biological Drugs Proliferating Growth of Self-Administration Shifting Demographics Device Design Innovation Competitive Landscape Risk Factors Pen Injector Design Selection Factors Standardized Pen Platforms Custom Pen Designs Reusable Pens Prefilled Pen Cartridges Disposable Pens Dual Chamber Pens Variable vs Fixed Dosing Autoinjectors Reusable Autoinjectors Disposable Autoinjectors Important Pen-Delivered Drug Classes Anticholonergics Dopamine Receptors Hematopoietics Human Growth Hormone Immune Modulators Insulins and Antihyperglycemics Parathyroid Hormone Reproductive Hormones Serotonin Antagonists Sympathomimetics Pen Injectors - Therapeutic Sector Assessment Anemia Inflammatory Autoimmune Diseases Diabetes Emergency Medicine Hepatitis Hormone Replacement Osteoporosis Reproductive Health Other Commercial Pen Markets & Products Market Factors Regulatory Considerations Patient Preferences and Compliance Managed Care Initiatives Private Labeling User-friendly syringe and injection device designs and the availability of an increasing number of drugs in pre-filled insertable and disposable cartridges are propelling the growth of prefilled syringes for selfadministration. The cost of biologicals such as recombinant proteins has created interest in prefilled syringes to reduce cost and waste associated with the handling of vialpackaged drugs. Company Profiles

2 Greystone Research Associates 1+603-595-4340 1+603-218-7020 clientservices@greystoneassociates.org Our reports are carefully researched and written to provide timely and insightful analysis of key factors and developments shaping the commercial marketplace. The focused nature of our publications is designed to allow readers to identify emerging demand and growth opportunities in selected markets. Numerous charts, tables and graphs complement the text, with evaluations and assessments of current and probable future market developments, technology issues and business factors - information necessary to compete effectively in the global marketplace. What You Will Learn Provides detailed analysis of pen injector market segments, market dynamics and market demographics Analyzes therapeutic demand drivers and evaluates commercial pen injector products in eleven major therapeutic segments Analyzes design factors, material selection issues, technologies and market development issues Provides Market Data to 2022 Profiles injectable drug and device participants, their pen injector product development activities, business strategies, and corporate alliances and affiliations Evaluates the impact of economic, technology, and regulatory factors Report Value Chain Who Should Read this Report Development Industry Market Drug Developers Device Suppliers CMOs Components/APIs Testing/Validation Clinical Trial Mgmt Pharma Managers Biotech Managers Drug Marketers Industry Strategists Financial Analysts Management Consultants Clinical Managers Drug Distributors Pharma Regulators FDA Consultants Managed Care Managers

5 Greystone Research Associates 1+603-595-4340 1+603-218-7020 clientservices@greystoneassociates.org Report Format and Availability This report is available electronic format. A single user license as well as licenses for multiple users are available. Custom licensing options to address specific company user requirements are available by calling client services at 603-595-4340, or by emailing clientservices@greystoneassociates.org. The Power of Insight Find us on the Web: www.greystoneassociates.org Methodology Research methodology is based on primary research in the form of indepth interviews with key market participants, technology developers, distributors, industry experts, and market influencers, a list that includes regulatory officials, industry trade groups, and materials standards organizations. Primary data is evaluated and normalized against secondary sources including trade journal articles, technical literature, industry publications, company data sheets and published information, and statistical data from government agencies and trade associations. Forecasts and projections of market demand and future market activity are derived using standard statistical techniques. Greystone Research Associates Greystone Research Associates is a medical technology consulting firm focused on the areas of medical market strategy, product commercialization, venture development, and market research. We assist medical and healthcare market participants in achieving their business objectives through the creation of detailed development strategies, product commercialization programs, and comprehensive market and technology research and analysis. Our market research publications are designed, researched and written to provide timely and insightful information and data on focused market segments, with the aim of providing market participants with the essential knowledge to refine and execute their marketing plans and financial targets.

6 How to Order Orders may be placed via postal mail, e-mail or fax. Orders not accompanied by a purchase order must contain a telephone number for verification, and clearly indicate the physical shipping address. Orders which are not prepaid must indicate the billing address. There is no charge for handling and shipping for destination addresses within the continental US. Payment We accept the following forms of payment: Company Check: Please make checks payable to Greystone Associates Credit Cards: We accept MasterCard, Visa and American Express Wire Transfers: See Wire Transfers below for more information Fax to: 603-218-7020 or email to clientservices@greystoneassociates.org Orders Outside the U.S. Orders must be prepaid via credit card, company check in US funds and drawn on a US bank, or wire transfer. Wire Transfers: TD Banknorth 300 Franklin Street Manchester, NH 03103 (Call for Account Information) Mailing Address: Greystone Research Associates Client Services P.O. Box 1362 Amherst, NH 03031 Pen Injectors to 2022 Devices, Drugs, Combination Products Select Format License Price (U.S. funds) Total PDF Single User $3,850.00 PDF Site License $5,500.00 PDF Global License $7,500.00 Total Payment (U.S. funds) Method of Payment: Company Check Wire Transfer Card Number: Name on Card Expiration Date: Card CVV Signature Billing Information Name: Title: Company: Street Address: City, State/Province: Country/Postal Code: Phone: Fax: Email: Shipping Information Click here if same as Billing Information Name: Title: Company: Street Address: City,State/Province: Country/Postal Code: Phone: Fax: Email: