3 rd International SMPS - Program

3 rd International SMPS - Program 3 rd International Symposium on Metabolic Programming and Stress (September 25-28, 2013) Morretes/PR, Brazil

Wednesday 25 th, Afternoon (Session 1: 15h:00min 16h:35min) Welcome (15h:00min 15h:15min) Paulo C.F. Mathias, PhD Laboratory of Secretion Cell Biology, Department of Biotechnology, Genetics and Cell Biology, State University of Maringa, Maringá/PR Brazil (pmathias@uem.br) Chair Elaine C. Vieira, PhD Lecture (15h:15min 15h:55min) Revisiting the fetal origin of adult diseases (FOAD) hypothesis: recent findings and future directions Didier Vieau, PhD University of Lille 1, Lille France (didier.vieau@univ-lille1.fr) Short Communication (15h:55min 16h:05min) Perinatal high-fat programming induces parasympathetic nervous system hyperactivity and affects pancreatic beta cell function in weanling rats Luiz F. Barella, PhD Laboratory of Secretion Cell Biology, Department of Biotechnology, Genetics and Cell Biology, State University of Maringa, Maringá/PR Brazil (lfbarella@gmail.com) Short Communication (16h:05min 16h:15min) Changes in muscarinic receptor subtypes composition in pancreatic islets from obese rats Rosiane A. Miranda, MSc Laboratory of Secretion Cell Biology, Department of Biotechnology, Genetics and Cell Biology, State University of Maringa, Maringá/PR Brazil (roapmiranda@yahoo.com.br) Discussion (16h:15min 16h:35min) Coffee-break (16h:35min 16h:45min)

Wednesday 25 th, Afternoon (Session 2: 16h:45min 18h:45min) Chair Patrícia C. Lisboa, PhD Full Communication (16h:45min 17h:25min) Involvement of pancreatic α-cells in the glucocorticoids-induced glucose dyshomeostasis Alex Rafacho, PhD Laboratory of Investigation in Chronic Diseases, Department of Physiological Sciences, Federal University of Santa Catarina, Florianópolis/SC Brazil (alex.rafacho@ufsc.br) Short Communication (17h:25min 17h:35min) Stressed pattern by maternal low-protein diet programs pancreatic β-cell function to resist dexamethasone disturbances in adult rat offspring Júlio C. de Oliveira, PhD Department of Physiological Sciences, Roberto Alcântara Gomes Biology Institute, State University of Rio de Janeiro, Rio de Janeiro/RJ Brazil & Laboratory of Secretion Cell Biology, Department of Biotechnology, Genetics and Cell Biology, State University of Maringa, Maringá/PR Brazil (biojborges@gmail.com) Short Communication (17h:35min 17h:45min) Hypothalamus-pituitary-adrenal axis disruption changes pancreatic islets muscarinic receptors composition in programming-obese rats Audrei Pavanello Laboratory of Secretion Cell Biology, Department of Biotechnology, Genetics and Cell Biology, State University of Maringa, Maringá Brazil (audreipavanello@hotmail.com) Full Communication (17h:45min 18h:25min) Early life protein malnutrition metabolic programming of insulin resistance in diet-induced obesity (DIO) Claudio C. Zoppi, PhD Department of Structural and Functional Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas/SP Brazil (claudiozoppi@hotmail.com) Discussion (18h:25min 18h:45min) Dinner (18h:45min)

Thursday 26 th, Morning (Session 1; 09h:00min 10h:20min) Chair Latifa Abdennebi-Najar, PhD Full Communication (09h:00min 09h:40min) Cardiovascular, renal and metabolic sequelae in offspring exposed in utero to a maternal diet high in saturated fat. James A. Armitage, PhD School of Medicine (Optometry), Deakin University; Waurn Ponds 3228, Victoria Australia (j.armitage@deakin.edu.au) Short Communication (09h:40min 09h:50min) The glucocorticoids and their effects on clock genes expressions from pineal glands. Rafaela E.A. Dantas Departamento de Morfologia, Universidade Federal de Sergipe, São Cristóvão/SE Brasil. (acmarcal@yahoo.com.br) Short Communication (09h:50min 10h:00min) Fetal programming in cardiovascular and metabolic diseases Paula H.O. Lima, PhD Laboratório de Investigação Molecular em Cardiologia, Instituto Dante Pazzanese de Cardiologia, Universidade de São Paulo (USP), São Paulo/SP Brasil (paula.lima@dantepazzanese.org.br) Discussion (10h:00min 10h:20min) Coffee-break (10h:20min 10h:30min)

Thursday 26 th, Morning (Session 2; 10h:30min 12h:30min) Chair Alex C. Manhães, PhD Full Communication (10h:30min 11h:10min) Leptin: new insights into IUGR pathology Latifa Abdennebi-Najar, PhD Unité de Recherche Expression des Gènes et Régulation Epigénétique par l'aliment, Institut Polytechnique LaSalle, Beauvais France (Latifa.Najar@lasalle-beauvais.fr) Short Communication (11h:10min 11h:20min) Short-term exercise prevents autonomic dysfunction related to obesity, but not cardiovascular changes induced by high-fat diet in rats Kesia Palma-Rigo, PhD Laboratory of Secretion Cell Biology, Department of Biotechnology, Genetics and Cell Biology, State University of Maringa, Maringá/PR Brazil (kesiapalmarigo@hotmail.fr) Short Communication (11h:20min 11h:30min) Insulin secretion and action are altered by in vitro amino-acid restriction: possible role of sirtuins Sarah Rickli Department of Structural and Functional Biology, University of Campinas (UNIICAMP), Campinas/SP Brazil (sarahhrickli@gmail.com) Full Communication (11h:30min 12h:10min) Neonatal environmental stress on neuronal changes and behavior in rats Aldo B. Lucion, PhD Departamento de Fisiologia, Instituto de Ciências Básicas da Saúde (ICBS); Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre/RS Brazil (alucion@ufrgs.br) Discussion (12h:10min 12h:30min) Lunch (12h:30min 14h:00min)

Thursday 26 th, Afternoon (Session 1; 14h:00min 16h:00min) Chair Aldo B. Lucion, PhD Full Communication (14h:00min 14h:40min) Metabolic flexibility in adipose tissue and skeletal muscle of MGS-obesity model is positively modified by chronic aerobic exercise Luiz C. Fernandes, PhD Federal University of Parana, Curitiba/PR Brazil (lcfer@ufpr.br) Short Communication (14h:40min 14h:50min) A role for chronic exercise on glucose metabolism of skeletal muscle from undernourished obese mice Nayara C. Leite, MSc Department of Structural and Functional Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas/SP Brazil (naaleite@hotmail.com) Short Communication (14h:50min 15h:00min) Characterization of MSG-induced obesity as a new model for polycystic ovary syndrome Renato S. Gaspar Department of Physiological Science, Federal University of Maranhao, São Luis/MA Brazil (marcuspaes@ufma.br) Full Communication (15h:00min 15h:40min) Evolutional characterization of nonalcoholic steatohepatitis in monosodium L-glutamate-induced obese mice Antônio M.A. Paes, PhD Department of Physiological Science, Federal University of Maranhao, São Luis/MA Brazil (marcuspaes@ufma.br) Discussion (15h:40min 16h:00min) Coffee-break (16h:00min 16h:10min)

Thursday 26 th, Afternoon (Session 2; 16h:10min 18h:10min) Chair Deborah M. Sloboda, PhD Full Communication (16h:10min 16h:50min) Breaking the programming fate: functional food (flaxseeds) and drugs (metformin and buscopan) Paulo C.F. Mathias, PhD Laboratory of Secretion Cell Biology, Department of Biotechnology, Genetics and Cell Biology, State University of Maringa, Maringá/PR Brazil (pmathias@uem.br) Discussion (16h:50min 17h:00min) Conference (17h:00min 17h:50min) The importance of a Brazilian DOHaD Society: perspectives and possibilities Chair Paulo C.F. Mathias, PhD Chair of the Conference for the Brazilian Society of DOHaD Deborah M. Sloboda, PhD Member of the International DOHaD Society Latifa Abdennebi-Najar, PhD Treasurer of the French Society of DOHaD Work-shop (17h:50min 18h:20min) Designing and manufacturing PowerLab/MacLab data acquisition systems for life science ADInstruments Company (http://www.adinstruments.com) Discussion (18h:20min 18h:30min) Dinner (18h:30min)

Chair Antônio M.A. Paes, PhD Friday 27 th, Morning (Session 1; 09h:00min 10h:20min) Full Communication (09h:00min 09h:40min) Metabolic compromise after early life nutritional adversity Deborah M. Sloboda, PhD Faculty of Health and Sciences, McMaster University, Hamilton/ON Canada (sloboda@mcmaster.ca) Short Communication (09h:40min 09h:50min) Neonatal serotonin reuptake inhibition promotes reduces metabolic indicators in adult rats Manuella L.D. Barros Departament of Physiotherapy, Federal University of Pernambuco (UFPE), Recife/PE Brazil (manuella.daluz@gmail.com) Short Communication (09h:50min 10h:00min) Endocrine and metabolic function are altered in a model of anxiety disorder Felippe Mousovich-Neto, MSc 1 Laboratório de Fisiologia Endócrina Doris Rosenthal (LFEDR), Instituto de Biofísica Carlos Chagas Filho (IBCCF), Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro/RJ Brasil. (felippeneto@hotmail.com) Discussion (10h:00min 10h:20min) Coffee-break (10h:20min 10h:30min)

Chair Elena Zambrano, PhD Friday 27 th, Morning (Session 2; 10h:30min 12h:30min) Full Communication (10h:30min 11h:10min) Differences in behavioral outcomes at adulthood between models of early weaning in rats Alex C. Manhães, PhD Departamento de Ciências Fisiológicas, Instituto de Biologia Roberto Alcântara Gomes, Universidade do Estado do Rio de Janeiro, Rio de Janeiro/RJ Brasil (amanhaes@uerj.br) Short Communication (11h:10min 11h:20min) Lactational serotonin reuptake inhibition increased hypothalamic expression of 5-HT 2C receptor in adulthood rats Lígia C.M. Galindo, PhD Postgraduate Nutrition, Department of Anatomy, Universidade Federal de Pernambuco (UFPE), Recife/PE Brasil (galindo.ligia1@gmail.com) Short Communication (11h:20min 11h:30min) Extraction, expansion and characterization of stem cells from fat tissue of individuals with metabolic syndrome Daniana M. Bronoski Biological and Health Science Multidisciplinary Laboratory, State University of Ponta Grossa, Ponta Grossa/PR Brazil. (daianabronoski@yahoo.com.br) Full Communication (11h:30min 12h:10min) Undernutrition and stress Ana L. Sawaya, PhD Universidade Federal de São Paulo, São Paulo/SP Brasil (alsawaya@unifesp.br) Discussion (12h:10min 12h:30min) Lunch (12h:30min 14h:00min)

Chair Alex Rafacho, PhD Friday 27 th, Afternoon (Session 1; 14h:00min 16h:00min) Full Communication (14h:00min 14h:40min) Insulin and insulin-like growth factor 1 signaling as a fine control on insulin synthesis, and their secretion from different animal models. Anderson C. Marçal, PhD Departamento de Morfologia, Universidade Federal de Sergipe, São Cristóvão/SE Brasil. (acmarcal@yahoo.com.br) Short Communication (14h:40min 14h:50min) Stress and melanoma: an in vitro evaluation of melanin production and tumor growth. Rebecca S.M. Stival Biological and Health Science Multidisciplinary Laboratory, State University of Ponta Grossa, Ponta Grossa/PR Brazil. (rebeccastival@hotmail.com) Short Communication (14h:50min 15h:00min) Metabolic programming by small litters impairs the VO 2max performance of rats during the exercise program Gabriel S. Fabricio Department of Physical Education, State University of Maringa, Maringá/PR Brazil (gabrielsergiofabricio@yahoo.com.br) Full Communication (15h:00min 15h:40min) Diet and exercise interventions before and in pregnancy prevent adverse programming offspring outcomes of obese mothers Elena Zambrano, PhD Department of Reproductive Biology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City Mexico (zamgon@unam.mx) Discussion (15h:40min 16h:00min) Coffee-break (16h:00min 16h:10min)

Chair Ana L. Sawaya, PhD Friday 27 th, Afternoon (Session 2; 16h:10min 18h:10min) Full Communication (16h:10min 16h:50min) Effects of early adrenaldemedullation on fat accumulation in lean and obese trained rats Ana E. Andreazzi, PhD Laboratory of Endocrine Neurophysiology and Physical Exercise; Department of Physiology; Federal University of Juiz de Fora, Juiz de Fora/MG Brazil (anaelizabio@yahoo.com.br) Short Communication (16h:50min 17h:00min) Duodenal-jejunal bypass improves insulin secretion stimulated by Cch and PMA in islets from obese rats Mariana C. Mendes Laboratório de Fisiologia Endócrina e Metabolismo, Universidade Estadual do Oeste do Paraná (UNIOESTE), Cascavel/PR Brasil (m.carlam@live.com) Short Communication (17h:00min 17h:10min) Effects of maternal separation on eating behavior and stress reactivity in rats Julliet A. de Souza Department of Nutrition, Health Centre (CCS) & Department of Anatomy, Centre of Biological Sciences, Federal University of Pernambuco, Recife/PE Brazil (jully_jesus@hotmail.com) Full Communication (17h:10min 17h:50min) Melatonin prevents insulin resistance and mitochondrial dysfunction induced by palmitate in rat primary skeletal muscle cells. Elaine C. Vieira, PhD Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Universidad Miguel Hernandez de Elche, Elche Spain (vieiraec@yahoo.com) Discussion (17h:50min 18h:10min) Entertainment (18:15min) A piece of music with the APAE Orchestra from Ponta Grossa (in the Main Square of Morretes) Dinner (20h:00min) Symposium gala dinner (Lamb barbecue) Pousada Hakuna Matata

Saturday 28 th, Morning (Final session; 09h:00min 12h:00min) Conference (09h:00min 11h:00min) Conference for setting up collaborations Chair Paulo C.F. Mathias, PhD The organizing members of the International Symposium on Metabolic Programming and Stress invites everyone to this session to tie new collaboration works and to discuss the organization for the 4 th International Symposium on Metabolic Programming and Stress. Coffee-break (11h:00min 11h:15min) Final discussion (11h:15min 11h:45min) Talking about the election and chosen for the next place where the 4 th International Symposium on Metabolic Programming and Stress could be held. Closing remarks (11h:45min 12h:00min) Marcos R.R. da Silva, MD, PhD State University of Ponta Grossa, Ponta Grossa/PR Brazil (marcos.rrod@uol.com.br)