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THE PONTIFICAL ACADEMY OF SCIENCES WORKSHOP ON BIG DATA AND SCIENCE: Relevance of Computational Sciences for Data Collection, Data Storage and Data Management in Basic and Applied Scientific Investigations 17-18 November 2015 Casina Pio IV Vatican City

2 BIG DATA AND SCIENCE

... I... BIG DATA AND SCIENCE 3

Programme TUESDAY 17 NOVEMBER 2015 Session 1-0 GREETINGS AND OVERVIEW 9:00 Welcome Speech Werner Arber (PAS President) 9:10 Welcome Greetings Marcelo Sánchez Sorondo (PAS Chancellor) 9:20 Outline of the entire Workshop Rafael Vicuña (PAS Academician) 9:35 Scope of the Workshop Takashi Gojobori (PAS Academician,KAUST,KSA / NIG,Japan) Session 1-1 GENOMICS 10:00 Data Analysis of cyanobactrial genomes John Archer (Principal Research Scientist, KAUST, KSA) 10:30 The architecture of human chromosomes: a new insight into genome organization Giorgio Bernardi (Professor at Rome 3 University in Rome, Italy) 11:00 Big Data in the Study of Early Microbial Life Bill Martin (Professor at Heinrich-Heine-Universität in Düsseldorf, Germany) 11:30 Data analysis of vertebrate genomes Norihiro Okada (Professor, TIT, Tokyo, Japan) 12:30 Lunch Session 1-2 EARTH SCIENCE AND DISASTER 14:00 Nuclear power plant safety and data Tomihiro Taniguchi (Former Vice Director-General of IAEA, and Visiting Professor, TIT, Tokyo, Japan) 14:30 Importance of Data Science Simon Hodson (CODATA Executive Director, CODATA/ICSU, Paris) 15:00 Big data for unlearning of nuclear issues after Fukushima Daiichi Accident Shu-ichi Iwata (Professor-Emeritus at Tokyo University, Tokyo, Japan) 15:30 Break 4 BIG DATA AND SCIENCE

Session 1-3 BIODIVERSITY AND EVOLUTION 16:00 Big data in biodiversity... 16:30 Use of the compositional neighbor-joining method of constructing phylogenetic trees in large data analysis Masatoshi Nei (Professor, Pennsylvania State University, US) 17:00 Big data and bacterial evolution Werner Arber (PAS President) 17:30 Experimental and Theoretical Approaches to Epistatic Interactions Shozo Yokoyama (Professor, Emory Univ., US) 18:30 Dinner Session 2-1 ASTRONOMY WEDNESDAY 18 NOVEMBER 2015 9:00 Historical data of astronomy José G. Funes (PAS member, Director of Vatican Observatory) TBC 9:30 Big data in astronomy Martin Rees (PAS Academician, Fellow of Trinity College and Emeritus Professor of Cosmology and Astorophysics at the University of Cambridge) 10:00 Big data and citizen science in astronomy Christopher Lintott (Professor of Astorophysics and Citizen Science lead in the Department of Physics at the University of Oxford) Session 2-2 HUMAN HEALTH 10:30 Inferring Biological Landscapes of Human Disease from Genome-Scale Data Partha Majumder (Director, NIBB, India) 11:00 Cancer and Big Data Chung-I Wu (Director, GIB, China) 11:30 Finding useful information in big biomedical data Vladmir Bajic (Director, KAUST,KSA) 12:00 Big data in malaria research... 13:00 Lunch BIG DATA AND SCIENCE 5

Session 2-3 SYSTEM 14:30 Big data in biological system Rafael Vicuña (PAS Academician, Pontificia Universidad Católica de Chile) 15:00 Data-centric science Genshiro Kitagawa (President of Research Organization of Information & System in Tokyo, Japan) 15:30 Big data in robotics Shuji Hashimoto (Vice President of Waseda University, Tokyo, Japan) 16:00 Big data in gene expression network system Wen-Hsiung Li (Director, Institute of Biodiversity, Academia Sinica, Taiwan) 16:30 Break Session 2-4 DATABASE 17:00 Big data in bioinformatics Janet Thornton (Director of EBI, UK) 17:30 Data in historical publications Cesare Pasini (PAS Academician, Prefect of Vatican Library, Vatican) TBC 18:00 Big data in... Ron Appel (Director, SIB, Switzerland) 18:30 Future in the big data problems in life science David Lipman (Director, NCBI/NIH, US) 19:30 Dinner 6 BIG DATA AND SCIENCE

List of Participants Speakers APPEL Ron ARBER Werner ARCHER John A.C. BAJIC Vladimir B. BERNARDI Giorgio CHUNG-I WU GOJOBORI Takashi HASHIMOTO Shuji IWATA Shuichi LI Wen-Hsiung LINOTT Christopher MAJUMDER Partha P. MARTIN William F. NEI Masatoshi OKADA Norihiro REES Martin TANIGUCHI Tomohiro VICUÑA Rafael WU Chung-I YOKOYAMA Shozo BIG DATA AND SCIENCE 7

8 BIG DATA AND SCIENCE

BIG DATA AND SCIENCE 9

10 BIG DATA AND SCIENCE

Chiesa di Santo Stefano degli Abissini St Stephen of the Abyssinians Church Sede della Pontificia Accademia delle Scienze Seat of the Pontifical Academy of Sciences (CASINA PIO IV) Ingresso del Perugino The Perugino gate Ingresso Musei Vaticani Entrance gate to the Vatican Museum Domus Sanctae Marthae Ingresso Sant Uffizio The Sant Uffizio gate Altare Tomba S. Pietro Altar of St Peter s Tomb Ingresso Sant Anna The Sant Anna gate THE PONTIFICAL ACADEMY OF SCIENCES CASINA PIO IV V-00120 VATICAN CITY Tel: +39 0669883451 Fax: +39 0669885218 Email: pas@pas.va For further information please visit: www.pas.va vers. 01 (06-08-2015)