May 2008 IHRA s 19 th Conference Barcelona, Spain. Rob Gray Regional Rep Population Services International / Asia robgray@laopdr.



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Preventing IDU initiation among drug-curious youth: An attempt to measurably reduce IDU initiation among youth in Central Asia May 2008 IHRA s 19 th Conference Barcelona, Spain Rob Gray Regional Rep Population Services International / Asia robgray@laopdr.com

Break The Cycle A program designed to reduce youth initiation of IDU in Central Asia with quantifiable indicators of success

One in Three Sharing needles accounts for about 1 in 3 of all new HIV cases outside sub-saharan Africa (1 in 10 if including sub-saharan Africa) Source: UNAIDS 2006

Needle Sharing and HIV Risk Estimated Per-Act Risk of HIV Infection Per 10,000 Exposures to an Infected Source* Exposure Route Risk Needle sharing Blood transfusion Needle-sharing injection-drug use Receptive anal intercourse Needle stick through the skin Receptive penile-vaginal intercourse Insertive anal intercourse Insertive penile-vaginal intercourse Receptive oral intercourse Insertive oral intercourse 9,000 67 50 30 10 6.5 5 1 0.5 is a 6x more efficient mode of HIV transmission i than Sex *Assumes no condom use Source: CDC 2005 (www.cdc.gov/mmwr/preview/mmwrhtml/rr5402a1.htm)

Where Does IDU Drive the HIV Epidemic? Source: WHO, UNAIDS No data reported 0% HIV/AIDS cases among IDUs < 10% HIV/AIDS cases among IDUs 10-40% HIV/AIDS cases among IDUs 40%+ HIV/AIDS cases among IDUs

Global Population of Drug Users High Concentration ti in Former Soviet Union Conservative estimates of the size of IDU populations in 130 countries and territories (1998-2003) Source: Reference Groups on the Prevention and Care and HIV/AIDS Among Injecting Drug Users, 2002

Registered Drug Users in Central Asia 1997-2003 350 300 000 250 200 150 100 50 Khazakstan Kyrgyzstan Tajikistan Registerede Drug users / 100, 0 1987 1988 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 Year Source: Centers for Disease Control

Injecting j g Drug g Use in Central Asia North of Afghanistan (source of 90% of world s heroin) Heroin cheap (1 shot = cost of restaurant meal) C. Asians tend to be less needle-phobic Opiates often used for medication in absence of strong health care system Youth often initiate drug use with opiates / injecting More than 70% of HIV cases related to IDU Overdose and HCV in epidemic proportions

2004: PSI launches project to reduce youth initiation iti of IDU in C. Asia The search for an evidence base on reducing IDU initiation The WHO had (has) no recommendations on how to prevent initiation of (injecting) drug use No well established models to follow Almost no consultants with drug expertise willing to provide guidance yet billions are spent each year on drug use prevention programs around the world

Initial Project Design Focusing on vulnerable youth PSI began with a project in 2004 Targeting youth at risk of IDU Targeting youth who regularly socialize with IDUs But the baseline survey resulted in self reported opiate use and/or injecting of less than 1%... Girlfriend/ Boyfriend IDU Coworker Hence, the Baseline Indicator Problem: No indicator against which to measure success Most projects ignore this problem and implement (often expensive) projects with no hope of measuring success because it s the right thing to do IDU IDU Sibling/ Cousin School friend

Back to the drawing board The Baseline Indicator Problem forced us back to the drawing board Without an indicator against which to measure success, we were not willing to proceed So we looked more carefully at the question: Why are C. Asian youth initiating injecting drugs?

Why are C. Asian young people p initiating IDU? Proximity it Direction of Opiate Trade from Afghanistan

Geographic Proximity Central Asian youth are particularly at risk of IDU initiation due to their proximity to the source of more than 90 percent of the world s opiate supply, transported through drug trafficking routes that cross through the region.* Opiates are readily available and inexpensive ($1.50 per dose in Tajikistan) * According to the UN Office on Drugs and Crime (UNODC), 12 to 13 percent of drugs produced in Afghanistan are transited through the `northern corridor, mainly passing through three countries - Tajikistan, Uzbekistan and Turkmenistan.

Why are C. Asian young people p initiating IDU? 1. Proximity 2. Exposure to IDU

Exposure Non-injectors often see IDU modeled in their daily lives Physical environment facilitates exposure to / comfort with IDU i.e. cramped living conditions Culture facilitates comfort with injecting i.e. injecting for medical reasons at home is common in former Soviet Union

Why are C. Asian young people p initiating IDU? 1. Proximity 2. Exposure to IDU 3. Curiosity

Curiosity Curiosity was the biggest reported driver of young people initiating.* Hearing about the benefits of injecting arouses curiosity in non-injectors. *Source: Longfield, Robinson, Gray, and Jones. 2004 March. A Qualitative Assessment of Youth and Adult Perspectives on Drug Use, Heroin, and Risk for HIV/AIDS in Tajikistan and Uzbekistan, Central Asia.

Why are C. Asian young people p initiating IDU? 1. Proximity 2. Exposure to IDU 3. Curiosity 4. Enablers

Enablers The majority of IDUs surveyed report that they received help when they initiated. In most cases, curious youth pressure the drug user to help them initiate. *Source: Preliminary findings from a 2006 study among IDUs in Uzbekistan and Kyrgyzstan

Why are C. Asian young people p initiating IDU? 1. Proximity 2. Exposure to IDU 3. Curiosity 4. Enablers Reducing enabling and exposure to injecting were the factors we felt we could reasonably expect to impact on given limited time, resources, and dfunding. To do this, we needed to work with drug users.

and then I met Neil Hunt

Acknowledgement to Neil Hunt, Jon Derricott, Andrew Preston, et.al. who pioneered the concept in the UK We found that the factors leading to IDU initiation iti in C. Asia were very similar to those identified by Hunt et.al. in the UK www.exchangesupplies.org

Break The Cycle Building off Neil Hunt s UK BTC model, we built a program designed to reduce youth initiation of IDU in Central Asia with quantifiable indicators to measure success

Final Project Design: Dual Target Groups Targeting youth regularly socializing with IDUs Targeting IDUs who may play a role in IDU initiation IDU IDU Girlfriend/ Boyfriend Coworker Girlfriend/ Boyfriend Coworker IDU IDU IDU School friend IDU School friend Sibling/ Cousin Sibling/ Cousin

Focusing on specific and measurably behaviors BTC supports pre-existing norms among people who use drugs to reduce: Helping others initiate IDU Injecting in presence of non-idus Talking about benefits of IDU

Focusing on specific and measurably behaviors BTC supports pre-existing norms among people who use drugs to reduce: Helping others initiate IDU Injecting in presence of non-idus Talking about benefits of IDU Research found these to be pre- existing norms among many drug users, making behavior change more realizable

Baseline IDU Survey 2006 Learning to inject is a social phenomenon IDU Baseline Survey Results (2006) Indicators 2006 (N=440) Got help on first injection 85.9% Usually injects self 76.8%

Baseline IDU Survey 2006 Learning to inject is a social phenomenon IDU Baseline Survey Results (2006) Indicators 2006 (N=440) Got help on first injection 85.9% Usually injects self 76.8% Who are the helpers?

Baseline IDU Survey 2006 Learning to Inject: AFamily Affair Sibling/Cousin 53 percent First Injection Helpers Uzbekistan & Kyrgyzstan (N=440) Friend 33 percent Other 12 percent Dealer 2 percent

Baseline IDU Survey 2006 Understanding di Helpers vs. Non-Helpers INDICATORS SEGMENTATION ANALYSIS Helped Did not help N=51 N=169 (23%) (77%) Sig. Was helped to initiate by brother/sister 49 51 NS Helped by someone to initiate 95 84 * Injects every day 43 43 NS When I am dope sick, I will do anything to get a hit 31 48 * Reached by outreach worker in last 6 months 59 59 NS In last 6 months, talked to non-idu about benefits of IDU 49 30 * To reduce helping, Break The Cycle should: Help IDUs develop skills to avoid withdrawal (which leads to risk behaviors like sharing needles and initiating others in exchange for drugs) Target IDUs who themselves were helped to initiate, as they are more likely to initiate others

An overview of the Intervention: Break The Cycle in C. Asia (2006-2008) 2008) Intervention Summary Worked in Tashkent (Uz) and Bishkek (Kyrg) Project implemented 2006-2008 Drug users closely involved in program design and all trainings Project delivered through existing drug services (NSPs, rehabs, etc.) Used existing outreach workers (mostly drug users) Motivational interviewing used to deliver the intervention BTC integrated into other harm reduction topics covered by drug workers Building IDU capacity / supporting IDUs to deal with unwelcome request from drug curious youth and to reduce modeling of IDU to non-injectors IDU Response to the project Project very well received by drug users Drug users appreciated being supported to deal with pressure from drugcurious youth (overturning the global stereotype of the predatory drug dealer trying to initiate your child into drug use) Many drug users willing to help reduce IDU initiation; IDUs not the source of the problem

Preliminary Results Baseline Survey conducted in 2006 Endline Survey conducted April 2008 Results preliminary Final report in June 2008

Preliminary Results Reduction in % of IDUs who helped others to initiate IDU in the last 6 months 2006 2006 (N=440) (N=220) vs. vs. 2008 2008 (N=856) (N=427);(p<0.001) one 25 23.2 lped some t injection 20 15 17.3 % IDU Us who he make a firs 10 5 9.8 8.4 0 2006 2008 2006 2008 Tashkent, Uzbekistan Bishkek, Kyrgyzstan

Preliminary Results MONITORING TABLE INDICATORS 2006 2008 N=440 N=856 Helped someone make a first injection (in last 6 months) 23.2% 9.8% (p<0.001) # of people helped with first injection 2.9 3.3 (ns)

Estimate of new IDUs (Baseline 2006) IDU Helpers In 2006 out of 100 IDUs 23 were helping 2. 9 people initiate IDU each 6 months resulting in 67 new IDUs 23 IDU Helpers 100 IDUs 67 new IDUs

Estimate of new IDUs (Endline 2008) IDU Helpers In 2008 out of 100 IDUs 9.8 were helping 3.1 people initiate IDU each 6 months resulting in 30 new IDUs 9.8 IDU Helpers 100 IDUs 30 new IDUs

Projected Health Impact Even a small reduction in new IDUs will result in: Reduced HIV incidence Reduced HCV incidence Reduced overdose deaths

Conclusions WHO has no guidelines on preventing IDU initiation Yet drug demand reduction programs receive large funding globally, despite on-going lack of strong evidence of impact As we build an evidence base on how to measurably reduce IDU initiation, funding should shift Based on the growing evidence base, WHO should develop global guidelines on reducing IDU initiation BTC doesn t have to work with all drug users; even a small reduction in IDU initiation will result in significant reductions of HIV, HCV, overdose The emerging evidence on how IDU initiation occurs gives us data to overturn the global stereotype of the predatory drug dealer trying to initiate your child into drug use Drug users want to be part of the solution on IDU initiation, and are not the source of the problem Existing harm reduction programs should consider incorporating Break the Cycle as a standard component of harm reduction programs (as is already happening in the UK) Break the Cycle should be prioritized for scale up in E. Europe, Russia, C. Asia, China, SE Asia where rates of IDU initiation and HIV among IDUs are both high

Acknowledgements The drug users in Uzbekistan and Kyrgyzstan who helped design and implement the program, and Neil Hunt Andrew Preston Richard Elovich Dave Burrows Kim Longfield Galina Karmanova Aibek Mukhambetov The staff of PSI C. Asia Thank you! Rob Gray Regional Rep PSI Asia robgray@laopdr.com