10 th Annual International Cord Blood Transplantation Symposium June 7-9, 2012 Preliminary Scientific Program Thursday, June 7 7:00 8:00 AM Breakfast in Exhibit Hall Session IA 8:00 10:00 AM Advances in Regenerative Medicine 8:00 8:30 AM Keynote Address: Hematopoietic stem cell engineering at a crossroads 8:30 9:00 AM Progress in cellular therapies 9:00 9:30 AM Translational potential of human pluripotent stem cells 9:30 10:00 AM Panel Discussion 10:00 10:20 AM Coffee Break in Exhibit Hall
Session IB 10:20 AM 12:00 PM 10:20 10:50 AM Efficacy of human cord blood cells in animal models of regenerative medicine 10:50 11:10 AM Rat models of HIE Cord Blood Hematopoietic Cell Transplantation for Possible Cure of HIV infection 11:10 11:25 AM My experience in being cured of HIV infection - Mr. Timothy Brown, The Berlin Patient 11:25 11:45 AM Cord blood transplants with homozygous CCR5-delta 32 units as a means of providing possible cure of HIV infection 11:45 12:00 PM Panel Discussion 12:00 1:00 PM Lunch in Exhibit Hall
Session IIA 1:00 3:00 PM 1:00 1:30 PM A report on progress in treating nonhematological disorders with cord blood stem cells 1:30 2:00 PM Autologous cord blood therapies for children with neurologic disorders 2:00 2:30 PM Pilot studies in other non-hematologic disorders 2:30 3:00 PM Panel Discussion 3:00 3:20 PM Coffee Break in Exhibit Hall Session IIB 3:20 5:00 PM 3:20 3:40 PM Efficacy of human cord blood cells in animal models of regenerative medicine 3:40 4:00 PM Rat models of HIE 4:00 4:30 PM Early clinical trials in regenerative medicine
4:30 5:00 PM Panel Discussion 5:00 PM Adjourn Friday, June 8 7:00 8:00 AM Breakfast in Exhibit Hall Session III 8:00 10:00 AM Current Status of CBT Including Comparison with Other Stem Cell Sources 8:00 8:30 AM Opening remarks and overview of CBT outcomes using single and double unit CBT grafts reported to Eurocord: European perspective 8:30 9:00 AM Overview of CBT outcomes using single and double unit CBT grafts reported to the CIBMTR: United States perspective 9:00 9:40 AM Debate: Unrelated and haploidentical donor transplantation vs Cord Blood 9:40 10:00 AM Q & A 10:00 10:20 AM Coffee Break in Exhibit Hall
Session IV 10:20 AM 12:15 PM Improving CBT: RIC Conditioning and Unit Selection 10:20 10:50 AM Review: Reduced intensity conditioning and its role in the transplantation of patients with co-morbidities and older patients 10:50 11:10 AM The significance of NIMA and IPA in donor selection 11:10 11:30 AM Selecting grafts for double unit transplantation 11:30 11: 50 AM New considerations in donor matching and how to trade off against cell dose (HLA-C; high resolution typing; vector and location of mismatch) 11:50 12:15 PM Q & A 12:15 1:15 PM Lunch in Exhibit Hall Session V 1:15 3:15 PM Improving CBT by Improved Conditioning and Augmenting Engraftment Via Enhanced Homing Strategies
1:15 1:35 PM Intermediate intensity conditioning as an alternative to high dose or nonmyeloablative conditioning 1:35 1:55 PM Treosulfan based conditioning for CBT 1:55 2:15 PM IPros and Cons of inclusion of ATG in the conditioning: Eurocord data 2:15 2.35 PM CBT with oral sitagliptin: Early clinical experience 2:35 2:55 PM PGE2 to enhance homing 2:55 3:15 PM Q & A 3:15 3:35 PM Coffee Break in Exhibit Hall Session VI 3:35 5:00 PM Improving CBT by Control of Infectious Complications 3:35 3:55 PM New anti-virals 3:55 4:15 PM New anti-fungals 4:15 4:35 PM Post-transplant immunization after CBT
4:35 5:00 PM Q & A 5:00 PM Adjourn Saturday, June 9 7:00 8:00 AM Breakfast in Exhibit Hall Session VII 8:00 9:55 AM Cellular Therapy in CBT 8:00 8:20 AM Off the shelf myeloid progenitors 8:20 8:40 AM Beyond myeloid expansion 8:40 9:00 AM Multi-valent viral CTLs generated from CB 9:00 9:20 AM DLI in CBT: When, How and for What 9:20 9:55 AM Q & A 9:55 10:15 AM Coffee Break in Exhibit Hall Session VIII 10:15 AM 12:00 PM Evolving Issues in CB Transplantation
10:15 10:45 AM Review of GVHD The present status of knowledge 10:45 11:05 AM Use of haplo-identical and third party donors to act as a myeloid bridge 11:05 11:25 AM Single unit CBT with haplo-identical grafts after reduced intensity conditioning 11:25 11:45 AM Single unit CBT and haplo-identical CBT for aplastic anemia 11:45 12:00 PM Q & A 12:00 1:00 PM Lunch in Exhibit Hall Session IX 1:00 5:00 PM Cord Blood Banking 1:00 1:20 PM HHS ACBSCT Recommendations 1:20 1:40 PM Balancing the goals of inventory growth & cord blood bank self-sufficiency 1:40 2:00 PM Navigating donor eligibility & risk 2:00 2:20 PM Quantifying donor eligibility and risk
2:20 2:40 PM Transplant center approaches to product selection 2:40 3:00 PM Q & A 3:00 3:20 PM Coffee Break in Exhibit Hall 3:20 4:00 PM Panel Discussion: The Impact of Cord Blood Banking Regulation 4:00 4:20 PM The transplant center perspective of CB banking regulation 4:20 4:40 PM The international perspective of CB banking regulation 4:40 5:00 PM Q & A 5:00 PM Adjourn