2015/2016. Heart and Stroke Foundation New Investigator Awards Guidelines Alberta. (Winter 2014 Competition)



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2015/2016 Heart and Stroke Foundation New Investigator Awards Guidelines Alberta (Winter 2014 Competition)

November, 2014 Heart and Stroke Foundation New Investigator Awards in Alberta The Heart and Stroke Foundation (HSF), Alberta New Investigator Awards support the achievement of the HSF Vision: Healthy lives free of heart disease and stroke. Together, we will make it happen. The initiative aims to nurture and build the capacity of Alberta s cardio and cerebrovascular research and increase impact on the HSF mission to prevent disease, save lives and promote recovery. Purpose The New Investigator Awards aim to provide outstanding Alberta investigators in their early career with the opportunity to establish research programs and build teams through provision of a contribution to their group research efforts, laboratories or salary. The intent is to foster research excellence and support retention of outstanding talent in Alberta. Description This initiative provides salary support to excellent Alberta applicants whose innovative research plans have demonstrated strong potential to deliver impact on the HSF mission. The applicants are expected to demonstrate that their overall research program and plan have a cardio or cerebrovascular focus. An applicant may not be in receipt of another major Personnel award (i.e. from another national funding agency) and a Canada Research Chair at the same time as holding the Alberta New Investigator Award. However, an awardee may accept supplemental funding (no greater than 50% of the value of the HSF award), if it is from a local, institutional or provincial funding source. Eligibility The New Investigator Award of HSF, Alberta will be awarded to Alberta-based applicants with an MD, PhD, or equivalent degree who have clearly demonstrated potential to become an independent investigator. Specific eligibility criteria will include: 1. The applicants should be in 7 years or less from the start of their first faculty appointment. 2. The applicant should clearly demonstrate the potential to become an independent investigator. 3. The applicant must hold a faculty appointment at the time of award confirmation (i.e. July 1, 2015). New and upcoming appointees will be required to submit an official letter confirming appointment by the stipulated date with the application package. 4. Alberta applicants who have completed a HSFC New Investigator award or are in their final year of the term are eligible to apply. 5. Applicants are not allowed to hold one new and one existing Alberta New Investigator Awards at one time. 6. Applicants are allowed to apply for only one Alberta Initiative in a given competition (i.e. New Investigator or Seed Grant). 7. Applications for this award must be supported by the university or institution at which the applicant will conduct the proposed research. The university or institution is expected to guarantee the applicant appropriate academic rank and to provide adequate space and facilities for the investigator s research, commensurate with the status of the individual s experience and level of support by HSF. 8. The Dean and Department Head (or institutional equivalents) must guarantee at least 75% of the applicant s time allocated to research. 9. The applicant must hold a Grant-In-Aid in support of the proposed research at the time of this award; such grant(s) may be from the Heart and Stroke Foundation and/or other granting agencies. The research grant support has the following additional requirements: a. For each year of the three (3) years of the award, the recipient must be a Principal Investigator on a peer-reviewed grant originating from a national or provincial funding agency, irrespective of the amount of the grant. Heart and Stroke Foundation, Alberta New Investigator Awards Guidelines (2015/2016) Page 2 of 6

b. The recipient must have at least $30,000 per year of research funding for which he/she can either be principal or co-investigator. Value and Term 1. The Award offers $60,000 per annum for a maximum of 3 years which includes the employer s share of benefits. The award cannot be renewed for a second term. There are no additional allowances. 2. The Foundation does not impose any restriction on the additional income the awardee may earn, provided it is within the guidelines of the university or institution and that such activity does not impinge upon the time dedicated to the proposed research. 3. The recipient will be considered as an employee of the sponsoring university or institution and funds granted will be paid to the institution for payment to the recipient. The recipient will be a fulltime member of the staff with respect to the university or institution s policies. 4. The award may be terminated at any time for good cause by the recipient, the sponsoring institution, or HSF. 5. The recipient must immediately notify HSF should significant changes in research activities occur during the tenure of this award. Review Process All applications will undergo HSF peer review based on the following major criteria: Academic, research background and future potential of the applicant Research environment and Proposed research plan Application Guidelines Application Submission Deadline and Competition Results Applications must be received by the Heart and Stroke Foundation no later than 16:00 (MST) on February 17, 2015. HSF reserves the right to decline late or incomplete applications. One PDF copy of the full application package must be assembled and submitted to the Heart and Stroke Foundation, Alberta Provincial office to the following address: Research Department Heart and Stroke Foundation, Alberta 100-119 14 Street NW Calgary, Alberta T2N 1Z6 Applicants must submit the following documents: One (1) USB stick containing one (1) PDF of the complete application One (1) original copy of the signature page of the application Results will be posted on the HSF Research website (www.hsf.ca/research) in September 2015. Official award notifications will be sent out to the applicants in July, 2015. Re-Applying If three (3) unsuccessful applications have been made, a subsequent application will be considered only in unusual circumstances. Multiple Submissions Multiple submissions for any given competition are not permitted. Where partnership programs are in place, the applicant must contact HSF for more information. Partial Awards Partial awards of less than three (3) years are not granted under this initiative. Heart and Stroke Foundation, Alberta New Investigator Awards Guidelines (2015/2016) Page 3 of 6

Transfer of Award Under any circumstances, the Awards are not transferable to institutions or universities outside Alberta. The awardee must immediately notify HSF should he/she be unable to continue his/her current research program. Closing of Award When work is completed, or if for any reason the work cannot be continued, the award will be closed. Any remaining funds cannot be reallocated to other use. The institution will prepare the final accounting statement and return outstanding funds to HSF. Prolonged Absence from Work The awardee is required to notify HSF of any illness or other cause necessitating absence from work exceeding thirty (30) successive days. Continuation of the award will be at the discretion of the Foundation. Non-Employee Status The granting of an award is deemed to establish neither an employer-employee relationship nor a partnership between the grantor and the grantee. Public Information If successful, the title of research project and the lay summary may be used by research promotion without notification to the respective researcher. Applicants are therefore advised not to disclose information that could endanger a proprietary position in these sections. Four Themes of Health Research Applicants must estimate what proportion of the proposed research and proposed project budget falls under the four health research themes. This data is gathered for internal use only. The four (4) themes of health research as defined by the Canadian Institutes of Health Research are: 1. Basic Biomedical (Pillar I) Research with the goal of understanding normal and abnormal human function, at the molecular, cellular, organ system and whole body levels, including the development of tools and techniques to be applied for this purpose; developing new therapies or devices which improve health or the quality of life of individuals, up to the point where they are tested on human subjects. Studies on human subjects that do not have a diagnostic or therapeutic orientation. 2. Clinical (Pillar II) Research with the goal of improving the diagnosis and treatment (including rehabilitation and palliation) of disease and injury; improving the health and quality of life of individuals as they pass through normal life stages. Research on, or for the treatment of, patients. 3. Health Services/Systems (III) Research with the goal of improving the efficiency and effectiveness of health professionals and the health care system, through changes to practice and policy. Health services research is a multidisciplinary field of scientific investigation that studies how social factors, financing systems, organizational structures and processes, health technologies, and personal behaviours affect access to health care, the quality and cost of health care, and ultimately our health and well-being. 4. Social, Cultural, Environmental and Population Health (IV) Research with the goal of improving the health of the Canadian population, or of defined sub-populations, through a better understanding of the ways in which social, cultural, environmental, occupational, and economic factors determine health status. Heart and Stroke Foundation, Alberta New Investigator Awards Guidelines (2015/2016) Page 4 of 6

Ethical Requirements By signing and submitting applications to HSF, applicants undertake the responsibility to ensure any experimentation will be acceptable to the institution on ethical grounds and comply with the following guidelines and host institution research policies, as applicable: Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans 1 Good Clinical Practice (GCP) Good Laboratory Practice (GLP) In the case of laboratory animal experimentation, the guiding principles and standards enunciated by the Canadian Council on Animal Care 2 Guidelines and standards for biological and chemical hazards as outlined in the Public Health Agency of Canada Laboratory Biosafety Guidelines 3 Any research involving human pluripotent stem cells must adhere to the CIHR Guidelines for Human Pluripotent Stem Cell Research. The institution must notify HSFC as to the results of the review by the CIHR s Stem Cell Oversight Committee 4 1 See www.ethics.gc.ca/eng/policy-politique/initiatives/tcps2-eptc2/default/ for details. 2 See www.ccac.ca/en_/standards/guidelines for details. 3 See www.phac-aspc.gc.ca/lab-bio/res/blk-acb/lbg-ldmbl-eng.php for details. 4 See www.cihr-irsc.gc.ca/e/42071.html for details. Indirect Costs The HSF supports only the direct costs of research. No funding is to be used for indirect costs of research. The definition of indirect costs of research for the purposes of this policy is, costs which cannot be directly associated with a particular research program or operating grant including: costs associated with the general operation and maintenance of facilities (from laboratories to libraries); the management of the research process (from grant management to commercialization), and regulation and safety compliance (including human ethics, animal care and environmental assessment. Open Access to Research Outputs policy HSF requires that all researchers supported in whole or in part through the Foundation make their research outputs publicly available as soon as possible but no later than six months after the final publication or availability of results. HSF defines research outputs as peer-reviewed journal publications, research data, and the results of clinical trials that will not be published in peer-reviewed journals. Compliance with the Open Access to Research Outputs policy is a condition of acceptance of all HSF research funding. Please review HSF s policy at: http://www.hsf.ca/research/en/hsfopen-accessresearch-outputs-policy-guidelines Research Integrity Policy The primary objective of the HSF s Research Integrity Policy is to protect and defend the integrity of the research process and to deal with allegations of scientific misconduct in a timely and transparent fashion. Responsibilities of researchers, institutions and the HSF with respect to research integrity are outlined in the Heart and Stroke Foundation (HSF) Framework: Responsible Conduct of Research (http://www.hsf.ca/research/en/node/800 ). As a condition of funding, all HSF grant and award recipients agree to comply with the Principles and Responsibilities set out in that policy, and the research misconduct provisions below. The HSF defines research misconduct to include actions that are inconsistent with integrity as defined by the Framework, and to include such actions as fabrication, falsification, or plagiarism in proposing, performing, or reporting research, or in reporting research results 4. HSF will deal with allegations of scientific misconduct in the following manner: Any allegation of scientific misconduct will be initially reviewed by HSF to determine whether an investigation is warranted. If it is felt that an investigation is required, HSF may request that this be conducted by the host institution of the individual considered to have performed the alleged Heart and Stroke Foundation, Alberta New Investigator Awards Guidelines (2015/2016) Page 5 of 6

misconduct. In allegations specifically related to the peer review process, the investigation may be conducted jointly by the institution and HSF. The HSF will not act on verbal allegations of misconduct. All allegations must be submitted in writing. Although the confidentiality of persons who submit an allegation of scientific misconduct will be protected as much as possible, it must be recognized that due process will often result in the identity of this person being released to the investigating institution. The institution will be required to submit a written report upon conclusion of the investigation. This report will summarize the findings of the investigation and any future actions that will be undertaken by the institute as a result of the findings. In cases where misconduct is concluded to have occurred, the HSF may apply sanctions against the individual(s) implicated. These sanctions will range from a reprimand letter to a ban from applying for or holding HSF funds for a set period of time. 4 Wording adopted from the US Department of Health and Human Services, Public Health Service Policies on Research Misconduct, Final Rule. May 17, 2005. Available from http://ori.dhhs.gov/documents/fr_doc_05-9643.shtml. Publications Recipients must acknowledge the support of HSF in all scientific communications and press releases related to their award. To facilitate the implementation of the Foundation s program for knowledge transfer and exchange, we request that HSF be notified in advance of the publication date of any major publications arising from the Foundation s funding support. Status of Publications Any manuscript, paper, etc. included with an application, but not yet published, must be accompanied by documentation from the journal verifying whether it has been submitted, accepted for publication or is in press. Letters indicating confirmation of acceptance for publication of a paper must be received by the Foundation no later than one week before peer review of each year. Monitoring Progress A progress report must be submitted to HSF upon completion of 18 months of the award as per HSF reporting template which will be available on the HSF website. Continuation of the award is contingent upon receipt of a satisfactory progress report. Final Report A final report must be submitted to HSF no later than six (6) months after completion/termination of the award. The final report template will be available on HSF website. Financial Report HSF requires, from the institution, a financial report of awards at the end of each granting year. Contact the Heart and Stroke Foundation at: Research Department Heart and Stroke Foundation, Alberta 100-119 14 Street NW Calgary, Alberta T2N 1Z6 Tel: 403 3517061 Email: tdybvig@hsf.ab.ca Website: www.heartandstroke.ab.ca Heart and Stroke Foundation, Alberta New Investigator Awards Guidelines (2015/2016) Page 6 of 6