HOW TO HANDLE INCIDENTAL MESENTERIC ABNORMALITIES AND LYMPH NODES SEEN ON MDCT

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HOW TO HANDLE INCIDENTAL MESENTERIC ABNORMALITIES AND LYMPH NODES SEEN ON MDCT Richard M. Gore, MD North Shore University Medical Center University of Chicago Evanston, Illinois SCBT/MR 2010 San Diego, California March 7, 2010 17:00-17:10 17:10

CT WHIRL SIGN First described in 1981: the small bowel loops encircling the SMA creating a whirl- like pattern Twist usually clockwise-degree of circulatory impairment depends on tightness of twist Traditionally has meant SB volvulus

CT WHIRL SIGN Small bowel encircling central vessels and twisting 90 sensitivity of 64% for small bowel volvulus Most cases of small bowel volvulus had a whirl sign 180 Most whirl signs prove not to be indicative of volvulus but often seen in patients with prior abdominal surgery. Gollub Clin Radiol 30: 25-32, 2006

CT WHIRL SIGN 33 of 1,493 scans shows the whirl sign > 90 radius of the whirl 11 of 33 were shown to have volvulus True volvulus usually show a radius > 180 Previous surgery and internal hernias decrease PPV of this finding Gollub JCAT 30: 25-32, 2006

INCIDENTAL MESENTERIC ABNORMALITIES

MISTY MESENTERY: DIFFERENTIAL DIAGNOSIS Mesenteric edema Lymphedema Inflammation Hemorrhage Neoplasms Mesenteric panniculitis

MESENTERIC PANNICULITIS Liposclerotic mesenteritis Mesenteric lipodystrophy Mesenteric lipomatosis Retractile mesenteritis

MESENTERIC PANNICULITIS Non-specific inflammation of the mesenteric adipose tissue with acute inflammatory changes and fat necrosis Chronically, when fibrosis is dominant called retractile mesenteritis

MESENTERIC PANNICULITIS Unknown etiology? related to trauma, ischemia, infection Related to vasculitis, granulomatous disease, pancreatitis, and malignancy Prevalance of 0.6%, usually as an incidental finding in middle or late adulthood

MESENTERIC PANNICULITIS: CT FINDINGS Mass of increased-attenuation attenuation mesenteric fat often containing small soft-tissue tissue nodes Maximum transverse diameter directed toward the left consistent with the orientation of the jejunal mesentery Infiltrated fat engulfs the mesenteric vessels and displaces adjacent bowel loops without invading them

MESENTERIC PANNICULITIS: CT FINDINGS Hypodense cyst-like areas and calcifications due to fat necrosis are rare 2 specific signs: tumoral pseudocapsule (60% of cases) and fat ring sign of a hypodense fatty halo surrounding mesenteric nodules and vessels (75%)

MESENTERIC PANNICULITIS: CT FINDINGS Hypodense cyst-like areas and calcifications due to fat necrosis are rare 2 specific signs: tumoral pseudocapsule (60% of cases) and fat ring sign of a hypodense fatty halo surrounding mesenteric nodules and vessels (75%)

MESENTERIC PANNICULITIS IN THE ONCOLOGY PATIENT Co-existence of neoplasms especially lymphoma, GI and GU adenocarcinomas in up to 69% of patients with MP PET if negative excludes tumoral mesenteric involvement PET if positive suggests coexisting metastatic deposits especially in patient with lymphoma Zissin Br J Radiology 79: 37-43, 2006

LYMPH NODE SIZE: UPPER LIMITS OF NORMAL Retroperitoneal Mesenteric Common Iliac External Iliac Internal Iliac Obturator Superior Rectal Pararectal Inguinal: Deep/Superficial Lateral Sacral 10 mm 9 mm 10 mm 7 mm 8 mm 5 mm 3 mm 10 mm 7 mm

ENLARGED MESENTERIC LYMPH NODES: CHILDREN Prominent lymph nodes >4 mm, < 20 mm seen on MDCT in 29.1% of children 10 years of age scanned for trauma Rathaus Br J Radiol 78: 30-33, 33, 2005 Enlarged ileocecal lymph nodes in 21% of asymptomatic children on US: nodes were oval shaped, flat, nontender Watanabe Pediatr Radiol 27: 860-864, 864, 1997

MESENTERIC ADENITIS PRIMARY SECONDARY LNs up to 5 mm in small bowel mesentery commonly found in normal patients Lucy AJR 184: 41-44, 44, 2005

ENLARGED ABDOMINAL LYMPH NODES IN END STAGE CIRRHOSIS Seen in 50% of patients 1.1 X 1.1 to 3.0 X 4.5 cm in size Portacaval space and porta hepatis Dodd Radiology 203: 127-130, 130, 1997

ENLARGED ABDOMINAL LYMPH NODES IN END STAGE CIRRHOSIS Primary biliary cirrhosis 86% Sclerosing cholangits 69% Cryptogenic biliary cirrhosis 64% Hepatitis B 49% Autoimmune cirrhosis 48% Hepatitis C 45% Alcohol abuse 37% Dodd Radiology 203: 127-130, 130, 1997