CIGNA-HEALTHSPRING ADOPTED PRACTICE GUIDELINE FOR THE TREATMENT OF PATIENTS WITH BIPOLAR DISORDER

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CIGNA-HEALTHSPRING ADOPTED PRACTICE GUIDELINE FOR THE TREATMENT OF PATIENTS WITH BIPOLAR DISORDER Ad Hoc Behavioral Health Guideline Committee Cigna-HealthSpring Clinical Guidelines and Steering Committee

Contents Overview 3 Obtaining APA Practice Guideline...3 Summary of Adopted Guideline...4 Provider Comment/Contact Information..7 References...8 2 P age

Overview This document is an overview of the Cigna HealthSpring adopted clinical practice guideline for the treatment of patients with Bipolar disorder. It is an adoption of the American Psychiatric Association Clinical Practice Guideline for the Treatment of Patients with Bipolar Disorder. Cigna HealthSpring has adopted this guideline as an evidenced base practice, not intended to supersede the clinical expertise and judgment of the practitioner, but to provide options for evidentiary support, diagnostic and treatment standardization and best practice decision making in managing Major Depression. Cigna HealthSpring recognizes that clinical exceptions to these best practices may arise and recommends that these be documented in the member s medical chart, including all pertinent rationales for treatment choices. The adoption of this guideline does not indicate that Cigna HealthSpring endorses any or all of the findings, determinations or offerings with regards to specific medications referenced in this or the American Psychiatric Association guideline. All Food and Drug Administration (FDA) warnings and guides and relevant formularies should be considered in determining treatment protocols. The treating clinician has the obligation to remain current on medication and equipment alerts or warnings that may be announced by the FDA and other regulatory sources. Obtaining the APA Clinical Practice Guideline The American Psychiatric Association (APA) Practice Guideline for the Treatment of Patients with Bipolar Disorder, Second Edition (2002 ) and Guideline Watch for the Practice Guideline for the Treatment of Patients With Bipolar Disorder(March 2009) is made freely available by the APA with all applicable copyright rules enforced. The complete text can be found at www.psych.org/psych_pract/treatg/pg/prac_guide.cfm. 3 P age

Cigna HealthSpring Adopted Guideline for the Treatment of Bipolar Disorder There are many interventions and activities available to the practitioner and member for the treatment of Bipolar Disorder. The following is a summary of the adopted APA Practice Guideline and does not represent all of the options, paths and information available in the complete text referenced above. Summary Psychiatric Management and Treatment of Bipolar Disorder Psychiatric Management includes: 1. Proper diagnosis 2. Safety and level of functioning assessment 3. Determination of the most appropriate treatment setting 4. Establishing and maintaining a therapeutic alliance 5. Monitoring functioning and psychiatric status. 6. Providing education regarding disorder 7. Promoting treatment adherence 8. Promoting healthy sleep/activity patterns 9. Anticipating stressors /early identification of new episodes/minimize functional impairment Diagnosis Reference Considerations Screen for Mood Disorder, as part of a full psychiatric evaluation DSM IV TR Mood Disorder Questionnaire APA Practice Guideline for psychiatric evaluation for Adults Clinical History, including time frames of mood changes; energy levels, sleep cycles; co morbidities, substance abuse, Safety evaluation Reference Considerations Screen for presence of suicidal/homicidal ideas, intent or plan; means/lethality of plan; command hallucinations; substance abuse APA Practice Guideline for the Treatment of Major Depression Determine level of care necessary for safety of patient or others, including hospitalization. Consider financial, social, sexual recklessness that 4 P age

previous attempts/family history of suicide/recent exposure to suicide may accompany manic phase Bipolar disorder Treatment Alliance Reference Considerations Long term management and alliance with consistent treatment professionals allow the acquisition of knowledge about the patient s course (cycles) and triggers. 5 P age Bipolar disorder is a persistent mental illness for which there is no cure. Long term management must be stressed Monitor Reference Considerations Regular visits to assess changes in mood, psychiatric status, illness cycles Sequence for early identification and intervention in depressive or manic episodes. Education Reference Considerations Patient education should be on going with a focus on facts about the illness Family education should be on going with focus on facts about the illness and how they can support ongoing treatment Treatment Phase Acute Patient education materials are available for a variety of sources, which can be found in the APA Practice Guideline for Treatment of Patients with Bipolar Patient education materials are available for a variety of sources, which can be found in the APA Practice Guideline for Treatment of Patients with Bipolar The ability to understand, accept, and/or adapt information about the illness will vary among patients. The ability to understand, accept, and/or adapt information about the illness will vary among families. Bipolar Manic or Mixed Intervention Considerations Severe disturbance Mood Stabilizer + antipsychotic medication Taper anti depressants May consider short term Benzodiazine as an add on; Less severe disturbance Antipsychotics with Bipolar indication Taper anti depressants Psychosocial Supports Co morbidities/supportive therapy/family supports

stabilizer and antidepressant Refractory Illness Consider change in mood stabilizer; consider change in antidepressant; consider electroconvulsive therapy Refractory Illness Trials of other mood stabilizers or antipsychotics; Consider Clozapine; consider electroconvulsive therapy Bipolar Depressed Intervention Considerations Bipolar Depressed Mood Stabilizer or mood Consider suicidality, comorbidities, psychosis Consideration of Bipolar I or II status should be made to assess risks of mania induction. Bipolar Rapid Cycling Intervention Considerations Four or more distinct episodes in one year. Separated by remission of at least 2 months. Identify/treat medical conditions that contribute to cycling Establish or check level of mood stabilizers Hypothyroidism; alcohol or substance abuse; medications Treatment Phase Continuation or Maintenance Following acute phase treatment, there is a high risk of relapse for up to six months Mood Stabilizers should remain in place; monitor the continued need for antipsychotic and antidepressant depending on the presentation Consideration of all medication side effects should be made. Special Clinical Features Psychosis More common with Bipolarmania Antipsychotics should be considered Catatonia Motor excitement, mutism, Benzodiazepines, ECT stereotypic movements, stupor Suicide/Homicide/violence Increased risk for suicide; Increased mortality from cardiovascular and pulmonary sources as well. Substance use disorders Increased rate of substance abuse disorders Identification and treatment concomitantly with Co Morbid Psychiatric Conditions Personality disorders, anxiety disorders, Attention deficit Hyperactivity Disorder Early identification and treatment of these disorders is important. 6 P age

Provider Comments Cigna HealthSpring values our clinical partners and requests your feedback, questions and or concerns regarding these guidelines. These may all be directed to: Clinical Director, Behavioral Health Cigna HealthSpring, Inc. 500 Great Circle Nashville, TN37228 615.565.8810 x508783 References The American Psychiatric Association (APA) Practice Guideline for the Treatment of Patients with Bipolar Disorder, Second Edition (2002) Guideline Watch for the Practice Guideline for the Treatment of Patients With Bipolar Disorder (March 2009) American Psychiatric Association Diagnostic and Statistical Manual of Mental disorder, 4 th Ed Test Revision 7 P age