Case Study: You ll notice some terms from the previous chapters. A 4 month old Irish Wolfhound named Gandolf is brought to the clinic after the owner noticed prolonged bleeding at the site of recent tooth loss. On P/E Gandolf had blood on his gingiva where his deciduous teeth recently fell out. Doctor ordered a CBC; below are the results: Patient Normal Range RBC ct 6.77x10 6 RBC/μl 5.00-10.00x10 6 RBC/μl WBC ct 8,422 WBC/μl 6,000-17,000WBC/μl Plt ct 101,000plt/μl 200,000-500,000Plt/μl 1. What does Gandolf have? a. Anemia b. Leukemia c. Thrombocytopenia 2. T or F Gandolf s condition is the most common inherited bleeding disorder of dogs. Exercises 8-A: Give the term for the following definitions. 1. : Red blood cell 2. : Granulocyte seen with allergies 3. : Agranulocyte that produces antibodies 4. : Oxygen carrying pigment of RBCs 5. : Hormone secreted by kidneys to stimulate erythropoiesis. 6. : Stopping or controlling of blood 7. : Immature monocyte 8. : Blood clotting 9. : Venipuncture 10. : Increase in cancerous WBCs 11. : Fat in the plasma 12. : Escape of blood from ruptured blood vessels.
8-B: Define the following terms. 1. Hemostasis 2. Neutropenia 3. Eosinophilia 4. Morphology 5. Thrombosis 6. Bilirubin 7. Antigen 8. Megakaryocyte 9. Packed Cell Volume 10. Dyscrasia 8-C: Answer the following questions. 1. What is the stimulus for lymphopoiesis? 2. What clotting factor is missing in Von Willebrand s Disease? 3. What causes aplastic anemia? 4. What is the function of a neutrophil? 5. Which organ conjugates bilirubin? 6. List 3 locations of macrophages. 7. If blood is placed in a Green TT then the fluid that results is called. 8. What is the difference between leukemia and leukocytosis? 9. Another name for erythrocytosis is. 10. The synonymous abbreviation for HCT is 11. T or F Thrombosis is the same as thrombocytosis. 12. What color is the plasma with hyperbilirubinemia?
8-D: Define the following abbreviations. 1. : CBC 2. : DIC 3. : hpf 4. : qns 5. : Diff 6. : Hgb 7. : AIHA 8. : TP 9. : IMHA 10. : lpf 8-E: Give the term for the following definitions. 1. Resembling bone marrow: myel 2. Pertaining to one nucleus: mono 3. Destruction of RBCs: lysis 4. Deficiency in all cells: penia 5. Disease condition of clotting: coagulo 6. Increase in WBCs: leuko 7. Blood condition of decreased albumin: hypo 8. RBCs are unequal in size: osis 9. State of equilibrium of the body s internal environment: stasis 10. Decrease in RBCs and/or Hb due to loss: anemia 8-F: Match the following terms with their descriptions. 1. Protein threads forming the basis of a clot A. Agranulocytes 2. Segs, Eos, Basos B. Albumin 3. Enzyme that converts fibrinogen to fibrin C. Fibrin 4. Lymphs, Monos D. Granulocytes 5. Maintains blood volume E. Thrombin
Answers: Case Study: 1. C 2. False it s the most common acquired bleeding disorder 8-A: 1. erythrocyte 7. monoblast 2. eosinophils 8. coagulation 3. lymphocytes 9. phlebotomy 4. hemoglobin 10.leukemia 5. erythropoietin 11.lipemia 6. hemostasis 12.hemorrhage 8-B: 8-C: 1. Hemostasis: Stopping or controlling blood 2. Neutropenia: Deficiency or decrease in neutrophils 3. Eosinophilia: Increase in eosinophils 4. Morphology: Study of shape 5. Thrombosis: Abnormal condition of clots or clotting 6. Bilirubin: Metabolite of hemoglobin breakdown 7. Antigen: Foreign protein that stimulates the production of antibodies 8. Megakaryocyte: Percursor to a platelet formed in the bone marrow 9. Packed Cell Volume: Percentage of RBCs in a volume of blood 10. Dyscrasia: Any abnormal condition of blood. 1. antigen 7. plasma 2. von willebrand s factor 8. leukemia is cancerous cells, leukocytosis has normal cells 3. no production 9. polycythemia 4. bacterial phagocyte 10. PCV 5. liver 11. False thrombosis is clots, thrombocytopenia is platelets or clotting cells 6. liver, spleen, and bone marrow 12. icteric 8-D: 1. Complete Blood Count 6. Hemoglobin 2. Disseminated Intravascular Coagulation 7. Autoimmune Hemolytic Anemia 3. High Power Field 8. Total Protein 4. Quantity Not Sufficient 9. Immune Mediated Hemolytic Anemia 5. White Blood Cell Differential 10. Low Power Field
8-E: 1. Myeloid 6. Leukocytosis 2. Mononuclear 7. Hypoalbuminemia 3. Hemolysis 8. Anisocytosis 4. Pancytopenia 9. Homeostasis 5. Coagulopathy 10. Hemorrhage 8-F: 1. C 2. D 3. E 4. A 5. B