Practice Problems Answer Key Chapter 28-Powdered Drug Preparations 1. 5 ml 100 mg 2. 45 ml 200 mg 3. 0.8 ml 200 mg 4. 8 ml 500,000 units 5. 0.2 ml 10,000 mg 100 mg 10,000 mg 100 ml Final Volume Powder Volume Final Volume Diluent added Powder Volume 100 ml 95 ml Powder Volume 5 ml 10,000 mg 200 mg 10,000 mg 50 ml Final Volume Diluent Added Final Volume Powder Volume Diluent Added 50 ml 5 ml Diluent Added 45 ml 1,000 mg 200 mg 1,000 mg 5 ml Final Volume Powder Volume Final Volume Diluent added Powder Volume 5 ml 4.2 ml Powder Volume 0.8 ml 20,000,000 units 500,000 units 20,000,000 units 40 ml Final Volume Powder Volume Final Volume Diluent added Powder Volume 40 ml 32 ml Powder Volume 8 ml 500 mg 500 mg 2 ml Final Volume Powder Volume Final Volume Diluent added Powder Volume 2 ml 1.8 ml Powder Volume 0.2 ml 6. 500,000 units/ml Final Volume 8 ml + 2 ml 10 ml 5 MU 5,000,000 units 5,000,000 units/10 ml 500,000 units/ml 7. 92.6 mg/ml Final Volume 10 ml + 0.8 ml 10.8 ml 1 g 1,000 mg 1,000 mg/10.8 ml 92.6 mg/ml Page 1 of 7
8. 83.3 mg/ml Final Volume 27 ml + 3 ml 30 ml 2.5 g 2500 mg 2500 mg/30 ml 83.3 mg/ml 9. 1.6 ml 3 G 3,000 mg 375 mg 3,000 mg 375 mg 3,000 mg 8 ml Final Volume Powder Volume Final Volume Diluent added Powder Volume 8 ml 6.4 ml Powder Volume 1.6 ml 10. 1 2 G 2,000 mg 180 mg 2,000 mg 180 mg 2,000 mg 1 Final Volume 11. 95.2 mg/ml 1 G 1,000 mg 1,000 mg/10.5 ml 95.2 mg/ml 12. 200 mg/ml Final Volume 26 ml + 4 ml 30 ml 6 G 6,000 mg 6,000 mg/30 ml 200 mg/ml 13. 115.4 mg/ml Final Volume 23 ml + 3 ml 26 ml 3 G 3,000 mg 3,000 mg/26 ml 115.4 mg/ml 14. 4 ml 20 G 20,000 mg 500 mg 20,000 mg 500 mg 20,000 mg 40 ml Final Volume Powder Volume 40 ml 36 ml Powder Volume 4 ml 15. 46 ml 20 G 20,000 mg 400 mg 20,000 mg 400 mg 20,000 mg 50 ml Final Volume Diluent Added 50 ml 4 ml Diluent Added 46 ml Page 2 of 7
16. 4.6 ml 4 G 4,000 mg 325 mg 2 ml 4,000 mg 325 mg 2 ml 4,000 mg 24.6 ml Final Volume Powder Volume Final Volume Diluent added Powder Volume 24.6 ml 20 ml Powder Volume 4.6 ml 17. 10.6 ml 1.5 g 1,500 mg 125 mg 1,500 mg 125 mg 1,500 mg 12 ml Final Volume Diluent Added Final Volume Powder Volume Diluent Added 12 ml 1.4 ml Diluent Added 10.6 ml 18. 129.7 mg/ml 2.75 g 2,750 mg Final Volume 19 ml + 2.2 ml 21.2 ml 2750 mg/21.2 ml 129.7 mg/ml 19. 429 mg/ml 30 g 30,000 mg Final Volume 64 ml + 6 ml 70 ml 30,000 mg/70 ml 429 mg/ml 20. 18.4 ml 5 g 5,000 mg 5,000 mg 5,000 mg 20 ml Final Volume Diluent Added Final Volume Powder Volume Diluent Added 20 ml 1.6 ml Diluent Added 18.4 ml 21. a) 14.5 ml b) 2.6 ml 2 g 2,000 mg 125 mg 2,000 mg 125 mg 2,000 mg 16 ml Final Volume Diluent Added Final Volume Powder Volume Diluent Added 16 ml 1.5 ml Diluent Added 14.5 ml 125 mg 325 mg 125 mg 325 mg 2.6 ml Final Volume Page 3 of 7
22. a) 0.2 ml b) 2.1 G 8 g 8,000 mg 800 mg 8,000 mg 800 mg 8,000 mg 10 ml Final Volume Powder Volume Final Volume Diluent Added Powder Volume 10 ml 9.8 ml Powder Volume 0.2 ml 10 ml 2.6 ml 8 G 10 ml 2.6 ml 8 G 2.1 G 23. 400 mg/ml Final Volume 94.8 ml + 5.2 ml 100 ml 40 G 40,000 mg 40,000 mg/100 ml 400 mg/ml 24. a) 3.6 ml b) 0.52 ml 1 G 1,000 mg 1,000 mg 1,000 mg 4 ml Final Volume Diluent Added Final Volume Powder Volume Diluent Added 4 ml 0.4 ml Diluent Added 3.6 ml 130 mg 1,000 mg 4 ml 4 ml 130 mg 1,000 mg 0.52 ml 25. 19.6 mg/ml Final Volume 100 ml + 2.3 ml 102.3 ml 2 G 2,000 mg 2,000 mg/102.3 ml 19.6 mg/ml 26. 16.8 ml 500,000 units 10,000,000 units 500,000 units 10,000,000 units 20 ml Final Volume Diluent Added Final Volume Powder Volume Diluent Added 20 ml 3.2 ml Diluent Added 16.8 ml 27. 250,000 units/ml Final Volume 36.8 ml + 3.2 ml 40 ml 10,000,000 units/40 ml 250,000 units/ml Page 4 of 7
28. a) 0.6 ml b) 0.8 ml 29. a) 0.8 ml b) 0.5 ml 1 G 1,000 mg 1,000 mg 1,000 mg 4 ml Final Volume Powder Volume Final Volume Diluent Added Powder Volume 4 ml 3.4 ml Powder Volume 0.6 ml 200 mg 200 mg 0.8 ml 5 mg 35 mg 5 mg 35 mg 7 ml Final Volume Powder Volume Final Volume Diluent Added Powder Volume 7 ml 6.2 ml Powder Volume 0.8 ml 5 mg 2.5 mg 5 mg 2.5 mg 0.5 ml 30. 1.25 mg/ml Final Volume + 0.2 ml 1.2 ml 1.5 mg/1.2 ml 1.25 mg/ml 31. A: 1 mg/ml B: 10 mg/ml 32. 10.4 ml 40 G 40,000 mg 400 mg 33. a) 19. 5 G 5,000 mg Medication A, 3.5 mg, is 10% of Medication B, 35 mg Total powder volume is 3.5 ml Medication A: 3.5 mg/3.5 ml 1 mg/ml Medication B: 35 mg/3.5 ml 10 mg/ml 40,000 mg 400 mg 40,000 mg 100 ml Final Volume Powder Volume Final Volume Diluent Added Powder Volume 100 ml 89.6 ml Powder Volume 10.4 ml 5,000 mg 5,000 mg 20 ml Final Volume Diluent Added Final Volume Powder Volume Diluent Added 20 ml 0.9 ml Diluent Added 19. Page 5 of 7
b) 2.4 ml 20 ml 5,000 mg 600 mg 20 ml 600 mg 5,000 mg 2.4 ml 34. 28.7 ml 9 G 9,000 mg 300 mg 9,000 mg 300 mg 9,000 mg 30 ml Final Volume Diluent Added Final Volume Powder Volume Diluent Added 30 ml 1.3 ml Diluent Added 28.7 ml 35. 1 G/ml Final Volume 3 + 4 ml 35 ml 35 G/35 ml 1 G/ml 36. a) 1 mg/ml b) 0.25 ml 37. Ampicillin /ml Sulbactam 125 mg/ml Final Volume 3.9 ml + 0. 4 ml 4 mg/4 ml 1 mg/ml 250 mcg 0.25 mg Therefore 0.25 ml are needed (since the ratio is 1 mg/ml) Final Volume 3.2 ml + 0.8 ml 4 ml 1 G 1,000 mg 0.5 G 500 mg Ampicillin: 1000 mg/4 ml /ml Sulbactam: 500 mg/4 ml 125 mg/ml 38. 37.6 ml 10 G 10,000 mg 10,000 mg 10,000 mg 40 ml Final Volume Diluent Added Final Volume Powder Volume Diluent Added 40 ml 2.4 ml Diluent Added 37.6 ml 39. a) 8 ml 20 MU 20,000,000 units 500,000 units 20,000,000 units 500,000 units 20,000,000 units 40 ml Final Volume Powder Volume Final Volume Diluent Added Powder Volume 40 ml 32 ml Powder Volume 8 ml Page 6 of 7
b) 16 ml 500,000 units 8,000,000 units 500,000 units 8,000,000 units 16 ml 40. 2 G/ml Final Volume 7.2 ml + 0.8 ml 8 ml 16 G/8 ml 2 G/ml 41. a) 0.2 ml 12.5 mg 50 mg 12.5 mg 50 mg 4 ml Final Volume Powder Volume Final Volume Diluent added Powder Volume 4 ml 3.8 ml Powder Volume 0.2 ml b) 1.5 ml 12.5 mg 18.75 mg 18.75 mg 12.5 mg 1.5 ml 42. 200 mcg/ml Final Volume 0.9 ml + 0. 0.2 mg/ 0.2 mg 0.2 mg 1,000 mcg 200 mcg/ml 43. 1.5 G Final Volume 0.7 ml + 9.3 ml 10 ml 5 G 10 ml 3 ml 44. a) 500,000 units/ml (0.5 mu/ml) b) 400,000 units/ml (0.4 mu/ml) c) 250,000 units/ml (0.25 mu/ml) d) 200,000 units/ml (0.2 mu/ml) 1.5 G Final Volume 32 ml + 8 ml 40 ml 20,000,000 units/40 ml 500,000 units/ml Final Volume 42 ml + 8 ml 50 ml 20,000,000 units/50 ml 400,000 units/ml Final Volume 72 ml + 8 ml 80 ml 20,000,000 units/80 ml 250,000 units/ml Final Volume 92 ml + 8 ml 100 ml 20,000,000 units/100 ml 200,000 units/ml Page 7 of 7