Pneumococcal Polysaccharide Vaccine - Pneu-P-23 Program

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Pneumococcal Polysaccharide Vaccine - Pneu-P-23 Program Sheila Kobitz/Jean Bode April 16, 2014 SCHR Telehealth Bug of the Month

Overview of Presentation Review of the impact of pneumococcal disease Review of Pneu-P-23 vaccine Pneu-P-23 vaccine eligibility Pneu-P-23 program

Pneumococcal Disease Impact Pneumococcal disease is caused by Streptococcus pneumoniae bacteria (S. pneumoniae). Invasive pneumococcal disease (IPD) is most common in the very young, the elderly and persons at high risk (such as those with functional or anatomic asplenia; congenital or acquired immunodeficiency).

Pneumococcal Disease Impact Can cause death (the overall fatality rate 5 7 %: much higher in the elderly) Serious life-threatening infections: Pneumonia (lungs) Meningitis (brain) Bacteremia (blood) Permanent complications include brain damage and deafness Otitis media in young children

Disease Distribution Among adults: 36% are community acquired 50% are hospital acquired In Canada between 2005 to 2008, incidence rates (per 100,000 population per year) of IPD were: 26.6 among infants less than 1 year of age (accounting for 3% of all IPD cases), and 20.4 among adults 60 years of age and older (accounting for 40% or all IPD cases).

Source The only natural reservoir is humans Many people carry the bacteria in their throat without getting sick Most children are colonized with and become carriers of one or more strains during the first year of life People with underlying medical, pulmonary conditions or immunosuppression are more likely to develop invasive disease

Transmission Spread from person to person by respiratory droplets: coughing, sneezing, through saliva, and close face to face contact A person can transmit the infection (period of communicability) as long as nasal and throat secretions contain pneumococci in large numbers; usually until 24 hours following appropriate antibiotic treatment.

Prevention Be immunized (direct protection) Be immunized to protect others (direct protection or herd immunity) Practice good hand hygiene and respiratory etiquette Don t share

History of Pneumo 23 Vaccine in Saskatchewan and SCHR September 1998 Publicly funded Pneumo 23 vaccine provided to residents of long term and personal care homes and those at highest risk September 1999 Pneumo 23 vaccine available for all high risk clients 2 years July 2009 Enhanced SCHR Pneumo 23 Immunization Program in acute care setting

Pneumococcal Polysaccharide Vaccine Pneu-P-23 Pneu-P-23 vaccine protects against 23 common strains of Streptococcus pneumoniae bacteria One dose is recommended for most people

S. pneumoniae serotypes included in pneumococcal vaccines Vaccines Serotypes 4 9V 6B 14 18C 19F 23F 1 5 7F 3 6A 19A 2 8 9N 10A 11A 12F 15B 17F 20 22F 33F Pneu-C-7 Pneu-C-10 Pneu-C-13 Pneu-P-23

Who Should Get the Pneu-P-23 Vaccine? Adults 65 years of age or older Residents of nursing homes / group homes and other chronic care facilities Persons 2-64 years of age with the following conditions (next 4 slides)

Persons 2-64 years of age with the following conditions: Alcoholism Chronic cerebrospinal fluid leak Chronic heart disease (all conditions) Chronic lung disease (excluding asthma, unless on high doses of oral corticosteroid therapy) Cystic fibrosis Diabetes mellitus

Persons 2-64 years of age with the following conditions: Homelessness Illicit drug use Neurologic conditions where the clearance of oral secretions is impaired Predialysis, peritoneal dialysis and hemodialysis Cochlear implant candidate or recipient

Persons 2-64 years of age with the following conditions: Anatomic or functional asplenia* Chronic liver disease (including nephrotic syndrome)* Chronic kidney disease (including nephrotic syndrome)* Congenital immunodeficiencies* Hematopoietic stem cell transplant recipient*

Persons 2-64 years of age with the following conditions: Sickle cell disease and other hemoglobinopathies* Solid organ or islet cell transplant candidate or recipient* Weakened immune system* related to: disease: malignant neoplasm including leukemia and lymphoma; HIV; multiple myeloma therapy: high dose, systemic steroids or severe rheumatoid arthritis requiring immunosuppressive therapy

*Eligible for Second Dose *Individuals with these specific conditions are at higher risk for pneumococcal disease, and are eligible for a second reinforcing dose 3-5 years after the first dose, depending on the client s age when the first dose was given (> or < than 10 years old)

Special Considerations Pregnancy can be provided as indicated for high risk individuals Splenectomy give vaccine at least 14 days before splenectomy, or, if not possible 14 days post-splenectomy. (If concerned that patient may not present later for immunization, give at hospital discharge) HIV early in the course of infection Immunosuppressive therapy before initiation

Who should not get the vaccine? Persons who have a serious illness, with or without a fever, should delay immunization Persons who have had a lifethreatening reaction to a previous dose of the vaccine, or who have severe allergies to any of the vaccine components

Possible reactions to the Pneu-P-23 vaccine Vaccines are very safe. It is much safer to get the vaccine than to get pneumococcal disease (remember the fatality rate for invasive pneumococcal disease from earlier in the presentation). Common expected reactions are: Soreness, redness and swelling at the injection site Headache and mild fever Mild reactions generally last 1 to 2 days

After Pneu-P-23 vaccine is given Client is given a wallet card indicating date of Pneu-P-23 immunization Client s Pneu-P-23 immunization is registered in Saskatchewan Immunization Management System (SIMS) Letter is sent to family physician informing them of client s Pneu-P- 23 immunization

SCHR Enhanced Pneumococcal 23 Immunization Program Introduced July 2009 (as an opportunity to start improvement prior to arrival of pandemic) Immunization of eligible acute care hospital patients and / or referral to Public Health for immunization if recommended Nurse is responsible for screening patient (according to eligibility criteria) on admission

Pneumococcal 23 Vaccine Assessment Form Review Pneu-P-23 immunization status for each eligible patient when admitted to hospital If patient has written confirmation of Pneu-P-23 vaccine (wallet card) please note this information on chart and record date on Pneumococcal 23 Vaccine Assessment form. A request to Public Health is not necessary and no further action required.

Pneumococcal 23 Vaccine Assessment Form Section 1 If patient has no written confirmation of Pneu-P- 23 vaccine, complete Pneumococcal 23 Vaccine Assessment form Section 1 (Acute Care On Admission) Include patients legal name, date of birth, gender, health services number,address and phone number (daytime /cell and evening) Have facility staff member fax form to Weyburn Public Health at 306-842-8637

Pneumococcal 23 Vaccine Assessment Form Section 2 Weyburn Public Health will check Saskatchewan Immunization Management System (SIMS) database to see if a record of Pneumococcal 23 immunization exists Public Health will complete Section 2: Record of previous Pneu-P-23 immunization in SIMS and will check off Yes/No boxes. If patient has received Pneu-P-23 Immunization the date(s) will be entered on the form The form will be faxed back to your facility

Pneumococcal 23 Vaccine Assessment Form Section 3 If there is a record of Previous Pneu-P-23 immunization in SIMS please record this in the patient s chart and attach the Pneumococcal 23 Vaccine Assessment Form to the chart If patient has no record of Pneu-P-23 immunization and requires immunization please arrange for follow up with Public Health

Pneumococcal 23 Vaccine Assessment Form Section 3 Inpatient: Advise patient to contact local Public Health Office to arrange an immunization appointment. Provide Pneumococcal Polysaccharide 23 Vaccine Fact Sheet May 2012 and appointment sheet if available.

Pneumococcal Polysaccharide 23 Vaccine Fact Sheet

Pneumococcal 23 Vaccine Assessment Form Section 3 Discharged: Fax form back to Weyburn Public Health at (306) 842-8637 for follow up by local Public Health Nurses

Pneu-P-23 Vaccine Follow Up Pneumococcal 23 Vaccine Assessment Form will be faxed to the local Public Health office where client resides Public Health nurse will contact individual to confirm eligibility and make arrangements for Pneu-P-23 if individual wishes to get vaccine.

Scenario 1 21 year old male patient into the hospital with asthma. Takes Ventolin and Flovent inhalers prn. Is he eligible for Pneumo 23 vaccine? No

Scenario 2 52 year old women has been hospitalized 3 times for pneumonia with no underlying medical conditions. Is she eligible for Pneumo 23 vaccine? No

Scenario 3 43 year old male with a long history of drug and alcohol abuse. Is he eligible for Pneumo 23 vaccine? Yes

Scenario 4 Pregnant 27 year old woman with diabetes mellitus. Is she eligible for Pneumo 23 vaccine? Yes

Questions

Thanks for your time!!!!

References Saskatchewan Immunization Manual 2012 - http://www.health.gov.sk.ca/immunization-manual Sask Ministry of Health Pneumococcal Polysaccharide 23 vaccine Fact Sheet May 2012 - http://www.health.gov.sk.ca/pneumococcal-disease-pneumo23 Communicable Disease Management Protocol Invasive Pneumococcal Disease (Streptococcus pneumoniae) (Pneumococcus) Manitoba Communicable Disease Control Branch 2011 - http://www.gov.mb.ca/health/publichealth/cdc/protocol/strep.pdf 2012 Canadian Immunization Guide - http://www.phacaspc.gc.ca/publicat/cig-gci/p04-pneu-eng.php MMWR (CDC) - http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5934a3.htm Picture Strep.jpg microbewiki.kenyon.edu