Vittorio Pengo M.D. (CV as of April 2014) Professor of Cardiovascular Medicine, Department of Cardiac Thoracic and Vascular Sciences, and Director of Thrombosis Center, University of Padova School of Medicine, Padova Italy Mailing Address: Clinical Cardiology, Thrombosis Center, via Giustiniani 2, 35128 Padova Italy M.D. degree University of Padova 1974 Residency Internal Medicine, University of Padova Certification Internal Medicine 1980 Cardiology 1985 Post Graduate training Clinical Medicine 1974-1983 Research Fellow, Cardeza Foundation, Philadelphia, PA, USA 1984-1985 Visiting scientist, Cardeza Foundation, Philadelphia, PA, USA, 1988 Clinical Cardiology 1988- Clinical Interests Research Interests Primary/secondary prevention and treatment of venous and arterial thromboembolism Pathophysiology and treatment of thrombosis Reviwer for the following Journals: New England Journal of Medicine, Circulation, Lancet, Blood, Journal of Thrombosis and Haemostasis, Thrombosis and Haemostasis, Thrombosis Research, American Journal of Cardiology, Haematologica, American Journal of Hematology, Journal of Cardiovascular Medicine, European Journal of Clinical Investigation, European Journal of Internal Medicine, Canadian Medical Association Journal Associate Editor of Internal and Emergency Journal since 2011 235 original papers in International Journals (Pub Med) Total Citations: >8000 and H index: 44 (Scopus). Padua, September 4, 2014 1
Major Publications Thiagarajan P, Pengo V, Shapiro SS. The use of the dilute Russel Viper Venom Time for the diagnosis of the lupus anticoagulant. Blood 1986;68:869-74. Pengo V, Thiagarajan P, Heine M, Shapiro SS. Immunological specificity and mechanism of action of IgG lupus anticoagulant.blood 1987;70:69-76. Pengo V, Biasiolo A, Fior MG. Autoimmune antiphospholipid antibodies are directed against a cryptic epitope expressed when 2-glycoprotein I is bound to a suitable surface. Thromb Haemost 1995;73:29-34. Pengo V, Biasiolo A, Brocco T, Tonetto S, Ruffatti A. Autoantibodies to phospholipid binding plasma proteins in patients with thrombosis and phospholipid-reactive antibodies. Thromb Haemost 1996;75:721-4. Palareti G, Leali N, Coccheri S, Poggi M, Manotti C, D'Angelo A, Pengo V, Erba N, Moia M, Ciavarella N, Devoto G, Berrettini M, Musolesi S. Bleeding complications of oral anticoagulant treatment: an inception-cohort, prospective collaboratory study (ISCOAT). Lancet 1996;348:423-28. Pengo V, Zasso A, Barbero F, Banzato A, Nante G, Parissenti L, John N, Noventa F, Dalla Volta S. Effectiveness of fixed mini-dose warfarin in the prevention of thromboembolism and vascular death in nonrheumatic atrial fibrillation. Am J Cardiol 1998;82:433-7. Pengo V, Brocco T, Biasiolo A, Rampazzo P, Carraro P, Zamarchi R. Procoagulant effect of anti-- 2 Glycoprotein I antibodies with Lupus Anticoagulant activity. Blood 1999;94:3814-9. Palareti G, Hirsh J, Legnani C, Manotti C, D Angelo A, Pengo V, Moia M, Guazzaloca G, Musolesi S, Coccheri S. Oral anticoagulation treatment in the elderly: a nested, prospective, case-control study. 2
Arch Inten Med 2000;160:470-81. Pengo V, Lensing AWA, Prins M, Marchiori A, Davidson B, Biasiolo A, Pegoraro C, Iliceto S, Prandoni P. High incidence of symptomatic chronic pulmonary hypertension after symptomatic pulmonary embolism. N Engl J Med 2004;250:2257-64. Palareti G, Cosmi B, Legnani C, Tosetto A, Brusi C, Iorio A, Pengo V, Ghirarduzzi A, Pattacini C, Testa S, Lensing AW, Tripodi A; PROLONG Investigators. D-dimer testing to determine the duration of anticoagulation therapy. N Engl J Med. 2006 Oct 26;355(17):1780-9. Amadeus Investigators, Bousser MG, Bouthier J, Büller HR, Cohen AT, Crijns H, Davidson BL, Halperin J, Hankey G, Levy S, Pengo V, Prandoni P, Prins MH, Tomkowski W, Torp- Pedersen C, Wyse DG.Comparison of idraparinux with vitamin K antagonists for prevention of thromboembolism in patients with atrial fibrillation: a randomised, open-label, non-inferiority trial. Lancet. 2008 Jan 26;371(9609):315-21. Pengo V, Cucchini U, Denas G, Erba N, Guazzaloca G, La Rosa L, De Micheli V, Testa S, Frontoni R, Prisco D, Nante G, Iliceto S; Italian Federation of Centers for the Diagnosis of Thrombosis and Management of Antithrombotic Therapies (FCSA). Standardized low-molecular-weight heparin bridging regimen in outpatients on oral anticoagulants undergoing invasive procedure or surgery: an inception cohort management study. Circulation 2009;119:2920-7. Pengo V, Noventa F, Denas G, Pengo MF, Gallo U, Grion AM, Iliceto S, Prandoni P. Long-term use of vitamin K antagonists and incidence of cancer: a population-based study. Blood. 2011;117:1707-9. Pengo V, Ruffatti A, Legnani C, Testa S, Fierro T, Marongiu F, De Micheli V, Gresele P, Tonello M, Ghirarduzzi A, Bison E, Denas G, Banzato A, Padayattil Jose S, Iliceto S. Incidence of a first thromboembolic event in asymptomatic carriers of high-risk antiphospholipid antibody profile: a multicenter prospective study. Blood. 2011;118:4714-8. Pengo V, Crippa L, Falanga A, Finazzi G, Marongiu F, Palareti G, Poli D, Testa S, Tiraferri E, Tosetto A, Tripodi A, Manotti C; Italian Federation of Thrombosis Centers. 3
Questions and answers on the use of dabigatran and perspectives on the use of other new oral anticoagulants in patients with atrial fibrillation. A consensus document of the Italian Federation of Thrombosis Centers (FCSA). Thromb Haemost. 2011 Nov;106(5):868-76. Pengo V. Laboratory tests during direct oral anticoagulant treatment? Yes. Intern Emerg Med. 2013 Aug;8(5):371-2. Pengo V, Ruffatti A, Del Ross T, Tonello M, Cuffaro S, Hoxha A, Banzato A, Bison E, Denas G, Bracco A, Padayattil Jose S. Confirmation of initial antiphospholipid antibody positivity depends on the antiphospholipid antibody profile. J Thromb Haemost. 2013 Aug;11(8):1527-31. Pengo V, Marongiu F; Members of the Steering Committee of the Italian Federation of Thrombosis Centers FCSA. Phase III studies on novel oral anticoagulants for stroke prevention in atrial fibrillation: a look beyond the excellent results: a reply to a rebuttal. J Thromb Haemost. 2013 Jun;11(6):1205-6. Pengo V, Banzato A, Denas G, Jose SP, Bison E, Hoxha A, Ruffatti A. Correct laboratory approach to APS diagnosis and monitoring. Autoimmun Rev. 2013 Jun;12(8):832-4. Pengo V, Banzato A, Bison E, Bracco A, Denas G, Ruffatti A. What have we learned about antiphospholipid syndrome from patients and antiphospholipid carrier cohorts? Semin Thromb Hemost. 2012 Jun;38(4):322-7. Associate Editor: Internal and Emergency Journal since 2011 4
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