[One point for every "yes"; a score of 2 indicates a likely case of anorexia nervosa or bulimia]

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Does my patient have an eating disorder? If you have a suspicion that your patient has an eating disorder, the Scoff questionnaire can help to prompt you to ask further detail questions. The SCOFF questions 1 Do you make yourself Sick because you feel uncomfortably full? Do you worry you have lost Control over how much you eat? Have you recently lost more than One stone in a 3 month period? Do you believe yourself to be Fat when others say you are too thin? Would you say that Food dominates your life? [One point for every "yes"; a score of 2 indicates a likely case of anorexia nervosa or bulimia] Further questioning will very likely indicate a diagnosis of an eating disorder. What food is safe and what food do you avoid? Do you vomit, take laxatives, diuretics, diet pills (and other drugs to lose weight) and exercise excessively? Do you lose control or binge eat? What is your current weight? What is your ideal weight? When did you last menstruate and have you missed any? Have you fainted or felt dizzy? How are your teeth? Do you feel colder compared to others? Do you feel weak when climbing the stairs? How is your sleep? Quick questioning on mood is equally important: How have you been feeling in yourself? How s your motivation? Do you have suicidal thoughts? 1 Morgan, J; BMJ 1999;319:1467-1468 ( 4 December )

What do I do now? Now that you think your patient has an eating disorder (or some kind of an eating disorder) and before referring your patient to the Eating Disorder Service at 25 Erleigh Road or Heatherwood Hospital: Physical examination Check weight and height for BMI in kg/m 2 Check blood pressure (lying and standing) and pulse rate Check for dehydration Check if there is oedema Full cardiovascular examination if there is cardiovascular compromise Other system examinations if indicated 2 Features of Medical Concern 3 Eating disorder features (if these features are present in combination, the level of concern is heightened): Marked undereating e.g. not eating at all during the day or under drinking Frequent vomiting i.e. >once a day Frequent laxative or diuretic misuse i.e. >once a day or less frequent if higher dose of intake Heavy exercising when underweight Rapid weight loss i.e. 1kg per week for for several weeks in succession Physical symptoms or signs (if these features are present in combination, the level of concern is heightened): Episodes of feeling faint or collapsing Episodes of disorientation, confusion or memory loss Awareness of the heart beating unusually or chest pains Unusual muscle twitches or spasms Shortness of breath Swelling of the ankles, arms or face Weakness and exhaustion Difficulty climbing stairs or getting up from a chair withoutusing the arms Blood stained vomit Investigations For everybody referred Blood tests: Urea & electrolytes and creatinine Full blood count For malnourished patients with BMI below 17.5 Blood tests: calcium Magnesium Phosphate Liver function test ECG 2 See Appendix 1 3 Fairburn, C.; Cognitive Behavior Therapy and Eating Disorders; p. 42

For overweight patients 4 Cholesterol Lipid profile Plasma glucose Thyroid function test For underweight patients who have not menstruated for 6 months DEXA bone density scan Oestradiol level for females For males who have been below BMI 17.5 for 6 months Testosterone level For patients with potassium less than 3.5 Very close monitoring of serum potassium and ECG Oral potassium supplement May require urgent medical/hospital referral Please see the Medical Risk Assessment Table to aid assessment prepared by Professor J. Treasure in Appendix 2 What treatment does my patient require? Always exclude medical risk, as your patient may need medical intervention first. If your patient refuses treatment consider the options below: 1. Treatment under common law if your patient requires urgent medical treatment 2. Treatment under the Capacity Act when there is medical risk 3. Treatment under the Mental Health Act for refeeding, orally or parenterally, against the patient s will to save life and or the patient has suicidal risk Medication of the selective serotonin reuptake inhibitor type is useful in bulimia nervosa in the short-term. Treat co-morbidities e.g. depression 5, obsessive compulsive disorder, substance misuse; some patients may need to be referred to the local mental health service or the substance misuse service. Close working with the different teams involved in the care of patients with general medical conditions and eating disorder is important, if not very important (e.g. a patient with diabetes mellitus may suffer disturbance of glycaemic control during therapy for eating disorder). Other general medical conditions may co-exist e.g. celiac disease, irritable bowel syndrome and food allergy. 4 Please also rule out Polycystic Ovarian Syndrome 5 Please see Appendix 2 on depression.

Appendix 1 Medical Risk Assessment for Eating Disorders 6 Professor Janet Treasure, Kings College London Name DoB Age SYSTEM Test * or Investigation No Concern Concern Alert Nutrition BMI <14 <12 Weight loss/week >0.5 kg >1.0 kg Skin Breakdown <0.1cm >0.2cm Purpuric rash + Circulation Systolic BP <90 <80 Diastolic BP <70 <60 Postural drop (sit stand) >10 >20 Pulse Rate ** <50 <40 Musculoskeletal (Squat Test and Sit up test) Unable to get up without using arms for balance + Unable to get up without using arms as leverage + Unable to sit up without using arms as leverage + Unable to sit up at all + Temperature <35 <34.5 Bone Marrow WCC <4.0 <2.0 Neutrophil count <1.5 <1.0 Hb <11 <9.0 Acute Hb drop ( MCV & MCH no acute risk) + Platelets <130 <110 Salt /water balance K+ <3.5 <3.0 Na+ <135 <130 Mg++ 0.5-0.7 <0.5 Phosphate 0.5-0.8 <0.5 Urea >7 >10 Liver Bilirubin >20 >40 Alkpase >110 >200 AsT >40 >80 ALT >45 >90 GGT >45 >90 Nutrition Albumin <35 <32 Creatinine Kinase >170 >250 Glucose <3.5 <2.5 ECG (if BMI<15, low K+, drugs prolonging QTC prescribed) Differential Diagnosis Pulse rate <50 <40 Corrected QT interval (QTC) >450 msec Arrythmias + TFT, ESR Any abnormal result is an indication for concern, monitoring and consultation/referral to specialist Eating Disorders Service. * The baselines for these tests may vary between labs. ** A tachycardia in the presence of signs and investigations of severe risk may be a harbinger of imminent cardiovascular collapse. 6 http://www.iop.kcl.ac.uk/sites/edu/downloads/hp

Appendix 2 Discriminatory Clinical Features Suggestive of a Co-Existing Clinical Depression 7 1. Recent intensification of depressive features (in the absence of change in eating disorder or social circumstances) 2. Heightened extreme and pervasive negative thinking (broader in content than eating related difficulties) Global negative thinking Hopelessnenss in general Recurrent thoughts about death and dying Suicidal thoughts and plan Undue guilt about events not related to eating disorder 3. Decrease in interests and involvement of others (above anything related to eating disorder) Decreased socialising Disengaeged inactivities already pursued 4. Decrease in drive and impaired decision-making Poor motivation Procastination 5. Other suggestive features Tearfulness Neglectful of personal care Neglectful of day-to-day activities Late onset of eating disorder (>30 years old) Atypical manner in treatment sessions Inability to undertake homework tasks through lack of drive 7 Fairburn, C.; Cognitive Behavior Therapy and Eating Disorders; p. 247

Clients When you are underweight, you 8 find it harder to eat because your stomach has shrunk. feel tired, weak and cold as your body's metabolism slows down. may become constipated. may not grow to your full height. may get brittle bones which break easily. The bone density scan shows whether you have osteopenia, the stage before osteoporosis and is reversible, or osteoporosis itself. may be unable to get pregnant. may damage your liver, particularly if you drink alcohol. may die, in extreme cases. Anorexia Nervosa has the highest death rate of any psychological disorder. If you vomit, you may: lose the enamel on your teeth (it is dissolved by the stomach acid in your vomit) get a puffy face (the salivary glands in your cheeks swell up) notice your heart beating irregularly - palpitations (vomiting disturbs the balance of salts in your blood) feel weak feel tired all the time damage your kidneys have epileptic fits be unable to get pregnant. If you use laxatives regularly, you may: have persistent stomach pain get swollen fingers find that you can't go to the toilet any more without using laxatives (using laxatives all the time can damage the muscles in your bowel) have huge weight swings. You lose lots of fluid when you purge, but take it all in again when you drink water afterwards (no calories are lost using laxatives). Seek urgent medical help, if you have: episodes of feeling faint or collapsing chest pains episodes of palpitations Do not hesitate to seek medical help if you are uncertain about your physical problems. 7 Information above for clients is adapted from the Royal College of Psychiatrists leaflet.

Carers 9 People whom you care for may report the following or you notice the physical problems yourselves. People who are underweight: find it harder to eat because the stomach has shrunk. feel tired, weak and cold as the body's metabolism slows down. may become constipated. may not grow to the full height. may get brittle bones which break easily. The bone density scan shows whether they have osteopenia, the stage before osteoporosis and is reversible, or osteoporosis itself. may be unable to get pregnant. may damage the liver, particularly if they drink alcohol. may die, in extreme cases. Anorexia Nervosa has the highest death rate of any psychological disorder. People who vomit may: lose the enamel on the teeth (it is dissolved by the stomach acid in the vomit) get a puffy face (the salivary glands in the cheeks swell up) notice the heart beating irregularly - palpitations (vomiting disturbs the balance of salts in the blood) feel weak feel tired all the time damage the kidneys have epileptic fits be unable to get pregnant. People who use laxatives regularly may: have persistent stomach pain get swollen fingers find that they can't go to the toilet any more without using laxatives (using laxatives all the time can damage the muscles in the bowel) have huge weight swings. They lose lots of fluid when they purge, but take it all in again when they drink water afterwards (no calories are lost using laxatives). Please don t wait for physical problems to appear to encourage seeking help. Some of the physical problems appear later in the progress of the eating disorder. The earlier the client receives help the better the outcome of the disorder. 9 Information above for carers is adapted from the Royal College of Psychiatrists leaflet.