THE BREAST COURSE 2013

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THE BREAST COURSE 2013 Learning objectives At the end of The Breast Course, the participant should be able to: 1. Explain the major pathologies affecting the breast; 2. Explain existing, novel and state-of-the-art breast imaging techniques; 3. Detect breast pathologies using conventional imaging technologies (mammography; ultrasound; magnetic resonance imaging) 4. Describe appropriate procedures for stereotactic, U/S, or MRI guided minimally invasive breast biopsy; 5. Select and utilize the appropriate sampling and guidance systems for optimal histological diagnosis when performing breast biopsy 6. Utilize the definitive histologic diagnosis provided by breast biopsy to reduce the number of surgeries required for diagnosis and therapy 7. Describe surgical management approaches of breast cancer; 8. Explain current procedures in pre-interventional neoadjuvant chemotherapy; 9. Explain current procedures in post-interventional adjuvant chemotherapy, brachytherapy and radiotherapy; 10. Learn to interact in an interdisciplinary fashion with fellow practitioners for breast patient care; and 11. Integrate most recent practice guidelines for small image-detected breast cancer in his/her daily practice. Target audience Our approach is interdisciplinary and hence, we welcome all breast professionals from many disciplines: Radiologists - Medical oncologists Surgeons Pathologists - Radiation oncologists - General practitioners Nurses Dosimetrists Technologists. Needs Assessment A Needs Assessment table has been completed (see attached) and was primarily based on the proceedings of the American Society of Breast Disease (ASBD) colloquium Ensuring Optimal Interdisciplinary Breast Care in the United States - Gaps, Implications, and Potential Measures to Assess Optimal Care. These needs were confirmed during past courses organized by DTR Inc., which included course evaluation forms and onsite electronic surveys on individual practice for more than 1,650 breast professionals trained in our last nine events. We also based our program on recent recommendations on breast care by the Canadian Association of Radiologists. Interaction The type and approximate duration in minutes of interaction are listed per session: Q: Question Period Qz: Quiz via electronic voting apparatus W: Case study workshop under expert guidance P: Panel discussion with audience participation S: Hands-on simulation under expert guidance

SUNDAY AM 14 APRIL 2013 SESSION 1 BREAST INTERVENTIONS Interventional radiologist: N. Duchesne / Moderator: E. Morris Panel: R. Wilson, M. Lagios, A. Purushotham Learning objectives: 4,5,10,11 8:00 AM Qz (10) Welcome address () The Breast Course Demographics E. Morris 8:15 AM Case presentations and management discussion R. Wilson 8:45 AM Q(15) Welcome address Breast biopsies demonstrations N. Duchesne 10:00 AM Refreshments 10:30 AM Q (15) Breast biopsies demonstrations (continued) N. Duchesne 12:00 PM Q (5) Surgical and biopsy specimen handling M. Lagios 12:30 PM

SUNDAY PM 14 APRIL 2013 SESSION II HIGH-RISK Moderator: R. Pijnappel Learning objectives: 1,3,6 1:30 PM Q (5) Breast anatomy/histology: fundamentals to understand staging and tumor grading A. Purushotham, M. Lagios 2:00 PM Q (5) High-risk pathologies M. Lagios 2:30 PM Q (5) High-risk lesion imaging presentation R. Pijnappel 3:00 PM Q (10) High-risk lesion obtained on image-guided biopsies: follow-up and management R. Wilson, E. Morris 3:30 PM Refreshments 4:00 PM Q (5) Genetic findings in breast cancer D. Armstrong 4:30 PM Q (5) Consensus of screening, follow-up and management of high-risk patients R. Pijnappel 5:00 PM P (30) Case presentations and management discussion: high-risk lesions M. Lagios; Panel 5:30 PM Departure 6:30 PM P (30) Live webinar: Interventional cases, management and follow-up R. Wilson

MONDAY AM 15 APRIL 2013 EARLY MORNING SESSION - INTERDISCIPLINARY (OPTIONAL) Learning objectives: 1,6,11 7:00 AM Q (5) Breast medical oncology explained: What you need to know D. Armstrong 7:50 AM Refreshments SESSION III DCIS UPDATE Moderator: M. Lagios Learning objectives: 1,6,11 8:00 AM Q (5) DCIS pathology update M. Lagios 8:30 AM Q (5) DCIS imaging update R. Pijnappel 9:00 AM Q (5) DCIS management update TBD 9:30 AM P (30) Case presentations and management discussion: DCIS R. Wilson, Panel 10:00 AM Refreshments SESSION IV INVASIVE BREAST CANCER MANAGEMENT Moderator: A. Purushotham Learning objectives: 6,7,9 10:30 AM Q (5) Imaging of invasive breast cancer with respect to its histology E. Wilson 11:00 AM Q (5) Lymph node imaging and intervention R. Wilson 11:30 AM Q (5) Surgery in the era of biomarkers and novel systemic and regional therapies A. Purushotham 12:00 PM Lunch period

MONDAY PM 15 APRIL 2013 SESSION V INVASIVE BREAST CANCER (CONTINUED) Moderator: D. Armstrong Learning objectives: 7,8,9,11 1:00 AM Q (5) Pre-operative MRI E. Morris 1:30 PM Q (5) Brachytherapy and external beam options TBD 2:00 PM Q (5) Neoadjuvant and adjuvant therapy options D. Armstrong 2:30 PM P (5) Case presentations and management discussion: invasive breast cancer R. Pijnappel; Panel 3:00 PM Refreshments SESSION VI MODALITY-SPECIFIC TOPICS Moderator: N. Duchesne Learning objectives: 2 3:30 PM Q(5) Breast tomosynthesis principles and case presentations R. Pijnappel 4:00 PM Q(10) Breast ultrasound: elastography, AWBUS and demonstration w/ volunteers N. Duchesne Practical workshop guidelines 5:30 PM Departure 6:30 PM P (30) Live webinar: Screening cases and their management: mammo, AWBUS, MRI N. Duchesne

TUESDAY AM 16 APRIL 2013 EARLY MORNING SESSION INTERDISCIPLINARY (OPTIONAL) Learning objectives: 1,6,11 7:00 AM Q (5) Breast surgery explained: What you need to know A. Purushotham 7:50 AM Refreshments 8:00 AM GROUP A Image-guided procedures workshop Wet demos: US-guided biopsies (N. Duchesne) Dry demos: Stereo-, MRI-guided biopsies, and CAD (E. Morris) Successful biopsy techniques across modalities (R. Pijnappel) SESSION VII PRACTICAL WORKSHOPS Learning objectives: 2,3,4,5 / 7,8,9,10 ANY GROUP Case presentations w/ electronic voting Screening mammograms: recall or no recall? (R. Wilson) Qz (120) S(120) 10:00 AM Refreshments 10:30 AM GROUP B Image-guided procedures workshop Wet demos: US-guided biopsies (R. Wilson) Dry demos: Stereo-, MRI-guided biopsies, and CAD (R. Pijnappel) Successful biopsy techniques across modalities (N. Duchesne) ANY GROUP Case presentations w/ electronic voting Breast MRI: screening, high risk DCIS and biopsies (E. Morris) Qz (120) ANY GROUP (MAX 50) Interdisciplinary board case studies DCIS management and radiotherapy options (M. Lagios, A. Purushotham) P(120) ANY GROUP (MAX 50) Interdisciplinary board case studies What are adequate margins for resection, with or without radiotherapy? (M. Lagios, A. Purushotham) P(120) S(120) 12:30 PM Lunch period

TUESDAY PM 16 APRIL 2013 Learning objectives: 2,3,4,5 / 7,8,9,10 1:30 PM GROUP C Image-guided procedures workshop Wet demos: US-guided biopsies (R. Pijnappel) Dry demos: Stereo-, MRI-guided biopsies, and CAD (E. Morris) Successful biopsy techniques across modalities (R. Wilson) SESSION VIII PRACTICAL WORKSHOPS ANY GROUP Case presentations w/ electronic voting Diagnostic cases presentation and management (nipple discharge; male breasts; implants; inflammatory breast; post-op breast; young patient) (N. Duchesne) Qz (120) S(120) 3:30 PM Refreshments 4:00 PM GROUP D Image-guided procedures workshop Wet demos: US-guided biopsies (N. Duchesne) Dry demos: Stereo-, MRI-guided biopsies, and CAD (R. Wilson) Qz (120) Successful biopsy techniques across modalities (R. Pijnappel) ANY GROUP Case presentations w/ electronic voting MRI cases false positive and pitfalls (E. Morris) ANY GROUP (FIRST 50) Interdisciplinary board case studies Lymph node pathological assessment, treatment options for minimal SN involvement, need for axillary irradiation when patient staged NImic on SN biopsy (M. Lagios, A. Purushotham, D. Armstrong) ANY GROUP (FIRST 50) Interdisciplinary board case studies TBD S(120) 6:00 PM Departure

WEDNESDAY AM 17 APRIL 2013 EARLY MORNING SESSION INTERDISICPLINARY (OPTIONAL) Learning objectives: 9,10 7:00 AM Q (5) Radiation oncology explained: What you need to know TBD 7:50AM Refreshments SESSION IX CURRENT CONTROVERSIES Moderator: R. Wilson Learning objectives: 6,8,9 8:00 AM Q (5) Breast cancer screening with mammography R. Wilson 8:30 AM Q (5) Role of nuclear imaging R. Pijnappel 9:00 AM Q (5) Oncotyping: What should be its influence on management? D. Armstrong 9:30 AM Q (5) Partial vs. conventional breast irradiation TBD 10:00 AM Refreshments SESSION X INTERDISCIPLINARY MANAGEMENT Moderator: N. Duchesne Learning objectives: 6,10,11 10:30 AM P (60) Return to live cases N. Duchesne, Panel 11:30 AM Q (5) Interdisciplinary management N. Duchesne 12:00 PM Departure