Projections of the Costs Associated with Cancer Care in the United States

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Projections of the Costs Associated with Cancer Care in the United States October 8, 2012 Robin Yabroff, Ph.D Health Services and Economics Branch Division of Cancer Control and Population Sciences National Cancer Institute yabroffr@mail.nih.gov

Overview Temporal cost patterns in cancer patients National estimates and projections Considerations in evaluating cost drivers Challenges in projecting cancer care costs Opportunities for improving cost estimates and projections

Monthly Medicare Payments for Colorectal Cancer Patients by Length of Survival $18,000 $16,000 $14,000 $12,000 $10,000 $8,000 $6,000 $4,000 36 Month Survival 48 Month Survival 60 Month Survival 72 Month Survival 84 Month Survival 96 Month Survival $2,000 $0 0 12 24 36 48 60 72 84 96 Months Month following After Diagnosis diagnosis SOURCE: Yabroff KR, Warren JL, Schrag D, Mariotto M, Meekins A, Topor M, Brown ML. Comparison of Approaches for estimating incidence costs for colorectal cancer patients. Med Care 2009;47:7(supp 1)S56-S63..

Phase of Care Approach for Estimating Cancer Costs Trajectory from diagnosis to death divided into clinically relevant periods or phases of care where flow of costs relatively homogeneous Initial Continuing Last year of life Phases can be predefined or determined empirically Can be used with longitudinal monthly survival probabilities to model incidence costs for a specific cohort Can be used with modeled prevalence by phase of care to estimate or project prevalence costs in a given year

Estimating and Projecting National Cancer Costs Dynamic U.S. population projections from Census Population aging and growing Incidence and survival rates projected based on most recent years of SEER data by cancer site and gender Incidence mostly declining Survival mostly improving Prevalence estimated and projected by phase of care for each cancer site by age and gender Linked SEER-Medicare data used to estimate net cost of care by cancer site, gender, and phase of care based on most recent data Source: Mariotto AB, Yabroff KR, Shao Y, Feuer EJ, Brown ML. Projections of the costs of cancer care in the United States: 2010-2020. J Natl Cancer Inst 2011;103:117-128.

Scenarios for Projecting National Cancer Care Costs Base case: constant current incidence, survival, cost based on most recent data Recent incidence and survival trend and assumptions about cost trends 2% increase annually in costs in initial and last year of life phases 5% increase annually in costs in initial and last year of life phases Source: Mariotto AB, Yabroff KR, Shao Y, Feuer EJ, Brown ML. Projections of the costs of cancer care in the United States: 2010-2020. J Natl Cancer Inst 2011;103:117-128.

Observed and projected SEER incidence rates Observed and projected SEER incidence rates Observed Projected current Continuing trend Source: Mariotto AB, Yabroff KR, Shao Y, Feuer EJ, Brown ML. Projections of the costs of cancer care in the United States: 2010-2020. J Natl Cancer Inst 2011;103:117-128.

Estimated National Expenditures for Cancer Care in 2010 by Site (in billion $) Breast Colorectal Lymphoma Lung Prostate Leukemia Ovary Brain Bladder Kidney Head_Neck Uterus Melanoma Pancreas Stomach Cervix Esophagus 0 5 10 15 20 Total Cancer Expenditure in 2010: $124.57 Billion in 2010 dollars Source: Mariotto AB, Yabroff KR, Shao Y, Feuer EJ, Brown ML. Projections of the costs of cancer care in the United States: 2010-2020. J Natl Cancer Inst 2011;103:117-128.

Estimated Proportion of National Expenditures for Cancer Care in 2010, by Site and Phase of Care Source: Mariotto AB, Yabroff KR, Shao Y, Feuer EJ, Brown ML. Projections of the costs of cancer care in the United States: 2010-2020. J Natl Cancer Inst 2011;103:117-128.

Projected Increase in National Expenditures in 2020 by Cancer Site (in billion $): Population Changes Only Breast Colorectal Lymphoma Lung Prostate Leukemia Ovary Brain Bladder Kidney Head_Neck Uterus Melanoma Pancreas Stomach Cervix Esophagus 0 5 10 15 20 25 Total Cancer Expenditure in 2020, Base Scenario: $157.77 Billion in 2010 dollars Source: Mariotto AB, Yabroff KR, Shao Y, Feuer EJ, Brown ML. Projections of the costs of cancer care in the United States: 2010-2020. J Natl Cancer Inst 2011;103:117-128.

Projections of National Cancer Care Expenditures in 2020 Recent incidence and survival trends, and 2% increase annually in costs in initial and last year of life phases $172.8 B (39% increase from 2010) 5% increase annually in costs in initial and last year of life phases $206.6 B (66% increase from 2010) http://costprojections.cancer.gov/ Source: Mariotto AB, Yabroff KR, Shao Y, Feuer EJ, Brown ML. Projections of the costs of cancer care in the United States: 2010-2020. J Natl Cancer Inst 2011;103:117-128.

Considerations when Evaluating Simultaneous Cost Drivers Population changes Incidence trends Stage Distribution at Diagnosis Survival trends Changes in use of services Targeted therapy Imaging Hematopoietic growth factors Hospice Changes in frequency and/or unit cost per service Hospitalizations

Monthly Costs of Cancer Drugs at FDA Approval Source: Bach PB. Limits on Medicare s Ability to control rising spending on cancer Drugs. N Engl J Med 2009;360:626-633.

Percentage of Total Medicare Payments in Year Following Diagnosis by Type of Service in 2002 100% 90% 80% 70% 60% 50% 40% 30% 20% Cancer related surgery Chemotherapy Radiation therapy Other hospitalizations Other services 10% 0% Breast cancer Colorectal cancer Lung cancer Prostate cancer Source: Warren JL, Yabroff KR, Meekins A, Topor M, Lamont EB, Brown ML. Evaluation of trends in the cost of initial cancer treatment. J Natl Cancer Inst 2008;100:888-897.

Proportion of Net Medicare Payments due to Hospitalizations in Elderly Cancer Patients, Initial Phase of Care Tumor Site Brain & ONS Female Breast Cervix Colorectal Corpus uteri Esophagus Gastric Head and Neck Leukemia Liver Lung Lymphoma Melanoma Ovary Pancreas Prostate Renal Urinary Bladder 0 10 20 30 40 50 60 70 80 90 100 Proportion Source: Yabroff KR, Lamont EB, Mariotto A, Warren JL, Topor M, Meekins A, Brown ML. Cost of care for elderly cancer patients in the United States. J Natl Cancer Inst 2008;100(9):630-641.

Proportion of Net Medicare Payments due to Hospitalizations in Elderly Cancer Patients, Last Year of Life Phase of Care Tumor Site Brain & ONS Female Breast Cervix Colorectal Corpus uteri Esophagus Gastric Head and Neck Leukemia Liver Lung Lymphoma Melanoma Ovary Pancreas Prostate Renal Urinary Bladder 0 10 20 30 40 50 60 70 80 90 100 Proportion Source: Yabroff KR, Lamont EB, Mariotto A, Warren JL, Topor M, Meekins A, Brown ML. Cost of care for elderly cancer patients in the United States. J Natl Cancer Inst 2008;100(9):630-641.

Challenges for Estimating and Projecting Cancer Costs Data completeness Care trajectory All payers by type, including out of pocket Under age 65 National Data comparability Population differences Methods for identifying cancer patients Type of data (Claims, encounter data, discharge, survey-based) Estimating and projecting treatment patterns Prevalence changes relatively slowly, but treatment patterns can change rapidly

Opportunities for Improving Cost Estimates and Projections Improved Data State-based linkage efforts Medical Expenditure Panel Survey (MEPS) Experiences with Cancer Survivorship Supplement Ongoing evaluation of trends Patterns of care Costs Comparative studies Cancer Research Network care and costs in managed care and fee-for-service elderly Patterns of care and costs in other countries

Acknowledgements Angela Mariotto Joan Warren Martin Brown Rocky Feuer