Creation Date 27-Feb-2014 Product Name SAFETY DATA SHEET 1. Identification Alcian Blue ph 2.5 Stain Revision Number 1 Cat No. : 88043 Synonyms Recommended Use Laboratory chemicals Uses advised against Details of the supplier of the safety data sheet No Information available Company Richard Allan Scientific A Subsidiary of Thermo Fisher Scientific 4481 Campus Drive Kalamazoo, MI 49008 Tel: (800) 522-7270 Emergency Telephone Number Chemtrec US: (800) 424-9300 Chemtrec EU: 001 (202) 483-7616 2. Hazard(s) identification Classification This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200) Skin Corrosion/irritation Category 2 Serious Eye Damage/Eye Irritation Category 1 Specific target organ toxicity - (repeated exposure) Category 2 Target Organs - Kidney, spleen, Blood. Label Elements Signal Word Danger Hazard Statements Causes skin irritation Causes serious eye damage May cause damage to organs through prolonged or repeated exposure Precautionary Statements Page 1 / 9
Prevention Wash face, hands and any exposed skin thoroughly after handling Wear protective gloves/protective clothing/eye protection/face protection Do not breathe dust/fume/gas/mist/vapors/spray Response Get medical attention/advice if you feel unwell Skin IF ON SKIN: Wash with plenty of soap and water If skin irritation occurs: Get medical advice/attention Take off contaminated clothing and wash before reuse Eyes IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing Immediately call a POISON CENTER or doctor/physician. Disposal Dispose of contents/container to an approved waste disposal plant Hazards not otherwise classified (HNOC) None identified 3. Composition / information on ingredients Haz/Non-haz Component CAS-No Weight % 2-Methyl-3-isothiazolone 2682-20-4 < 1.0 Acetic acid 64-19-7 2-3 Water 7732-18-5 95-97 5-Chloro-2-methyl-3-isothiazolone 26172-55-4 < 1.0 Copper(4+), [[N,N',N'',N'''-[29H,31Hphthalocyaninetetrayltetrakis[methylenethio[(dimethyl amino)methylidyne]]]tetrakis[nmethylmethanaminiumato]](2-)-n29,n30,n31,n32]-, tetrachloride 33864-99-2 <1 4. First-aid measures Eye Contact Skin Contact Inhalation Ingestion Most important symptoms/effects Notes to Physician Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Obtain medical attention. Wash off immediately with plenty of water for at least 15 minutes. Get medical attention immediately if symptoms occur. Move to fresh air. If breathing is difficult, give oxygen. Get medical attention immediately if symptoms occur. Do not induce vomiting. Obtain medical attention. Causes eye burns. Treat symptomatically. 5. Fire-fighting measures Suitable Extinguishing Media Unsuitable Extinguishing Media Substance is nonflammable; use agent most appropriate to extinguish surrounding fire.. Page 2 / 9
Flash Point Method - Autoignition Temperature Explosion Limits Upper Lower Sensitivity to mechanical impact Sensitivity to static discharge Specific Hazards Arising from the Chemical Thermal decomposition can lead to release of irritating gases and vapors. Hazardous Combustion Products Thermal decomposition can lead to release of irritating gases and vapors. Protective Equipment and Precautions for Firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear NFPA Health 2 Flammability 0 Instability 0 Physical hazards N/A 6. Accidental release measures Personal Precautions Environmental Precautions Methods for Containment and Clean Up Use personal protective equipment. Ensure adequate ventilation. Avoid contact with skin, eyes and clothing. Should not be released into the environment. See Section 12 for additional ecological Information. Soak up with inert absorbent material. Keep in suitable, closed containers for disposal. 7. Handling and storage Handling Storage Wear personal protective equipment. Ensure adequate ventilation. Do not breathe vapors or spray mist. Avoid contact with skin, eyes and clothing. Keep containers tightly closed in a dry, cool and well-ventilated place. 8. Exposure controls / personal protection Exposure Guidelines Component ACGIH TLV OSHA PEL NIOSH IDLH Acetic acid Copper(4+), [[N,N',N'',N'''-[29H,31Hphthalocyaninetetrayltetrakis[methyle nethio[(dimethylamino)methylidyne]]]t etrakis[n- methylmethanaminiumato]](2-)- N29,N30,N31,N32]-, tetrachloride (Vacated) (Vacated) TWA: 25 mg/m 3 TWA: 25 mg/m 3 IDLH: 50 ppm TWA: 25 mg/m 3 STEL: 37 mg/m 3 TWA: 1 mg/m 3 IDLH: 100 mg/m 3 TWA: 1 mg/m 3 Page 3 / 9
Component Quebec Mexico OEL (TWA) Ontario TWAEV Acetic acid TWA: 25 mg/m 3 STEL: 37 mg/m 3 TWA: 25 mg/m 3 STEL: 37 mg/m 3 Legend ACGIH - American Conference of Industrial Hygiene OSHA - Occupational Safety and Health Administration NIOSH IDLH: Immediately Dangerous to Life or Health Engineering Measures Ensure adequate ventilation, especially in confined areas. Ensure that eyewash stations and safety showers are close to the workstation location. Personal Protective Equipment Eye/face Protection Skin and body protection Respiratory Protection Hygiene Measures Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166 Wear appropriate protective gloves and clothing to prevent skin exposure Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced Handle in accordance with good industrial hygiene and safety practice 9. Physical and chemical properties Physical State Liquid Appearance Blue Odor vinegar-like Odor Threshold ph 2.5 Melting Point/Range Boiling Point/Range Flash Point Evaporation Rate Flammability (solid,gas) Flammability or explosive limits Upper Lower Vapor Pressure Vapor Density Relative Density Solubility Soluble in water Partition coefficient; n-octanol/water Autoignition Temperature Decomposition temperature Viscosity 10. Stability and reactivity Reactive Hazard Stability Conditions to Avoid None known, based on information available. Stable under normal conditions. Incompatible products. Excess heat. Page 4 / 9
Incompatible Materials Hazardous Decomposition Products Hazardous Polymerization Hazardous Reactions Strong oxidizing agents, Strong acids, Strong bases Thermal decomposition can lead to release of irritating gases and vapors Hazardous polymerization does not occur None under normal processing 11. Toxicological information Acute Toxicity Product Information No acute toxicity information is available for this product Component Information Component LD50 Oral LD50 Dermal LC50 Inhalation Acetic acid 3310 mg/kg ( Rat ) 1060 mg/kg ( Rabbit ) 11.4 mg/l ( Rat ) 4 h 5-Chloro-2-methyl-3-isothiazolone 481 mg/kg ( Rat ) 1008 mg/kg ( Rat ) 1.23 mg/l ( Rat ) 4 h Toxicologically Synergistic Products Delayed and immediate effects as well as chronic effects from short and long-term exposure Irritation Sensitization Carcinogenicity The table below indicates whether each agency has listed any ingredient as a carcinogen Component CAS-No IARC NTP ACGIH OSHA Mexico 2-Methyl-3-2682-20-4 Not listed Not listed Not listed Not listed Not listed isothiazolone Acetic acid 64-19-7 Not listed Not listed Not listed Not listed Not listed Water 7732-18-5 Not listed Not listed Not listed Not listed Not listed 5-Chloro-2-methyl-3-26172-55-4 Not listed Not listed Not listed Not listed Not listed isothiazolone Copper(4+), [[N,N',N'',N'''-[29H,31Hphthalocyaninetetrayltet rakis[methylenethio[(di methylamino)methylidy ne]]]tetrakis[nmethylmethanaminiuma to]](2-)- N29,N30,N31,N32]-, tetrachloride 33864-99-2 Not listed Not listed Not listed Not listed Not listed Mutagenic Effects Reproductive Effects Developmental Effects Teratogenicity STOT - single exposure STOT - repeated exposure Mutagenic effects have occurred in humans. Experiments have shown reproductive toxicity effects on laboratory animals. None known. Kidney, spleen, Blood. Page 5 / 9
Aspiration hazard Symptoms / effects, both acute and delayed Endocrine Disruptor Information Other Adverse Effects No information available Tumorigenic effects have been reported in experimental animals.. See actual entry in RTECS for complete information. 12. Ecological information Ecotoxicity. Component Freshwater Algae Freshwater Fish Microtox Water Flea Acetic acid Not listed Pimephales promelas: LC50 = 88 mg/l/96h Lepomis macrochirus: LC50 = 75 mg/l/96h Photobacterium phosphoreum: EC50 = 8.8 mg/l/15 min Photobacterium phosphoreum: EC50 = 8.8 mg/l/25 min Photobacterium phosphoreum: EC50 = 8.8 EC50 = 95 mg/l/24h 5-Chloro-2-methyl-3- isothiazolone 0.31 mg/l EC50 = 120 h 0.03-0.13 mg/l EC50 96 h 0.11-0.16 mg/l EC50 72 h mg/l/5 min 1.6 mg/l LC50 96 h EC50 = 5.7 mg/l 16 h 4.71 mg/l EC50 = 48 h 0.12-0.3 mg/l EC50 48 h 0.71-0.99 mg/l EC50 48 h Persistence and Degradability Bioaccumulation/ Accumulation No information available Mobility. Component log Pow Acetic acid -0.2 5-Chloro-2-methyl-3-isothiazolone 0.75 13. Disposal considerations Waste Disposal Methods Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. Chemical waste generators must also consult local, regional, and national hazardous waste regulations to ensure complete and accurate classification 14. Transport information DOT TDG IATA IMDG/IMO Not regulated Not regulated Not regulated Not regulated 15. Regulatory information Page 6 / 9
International Inventories 15. Regulatory information Component TSCA DSL NDSL EINECS ELINCS NLP PICCS ENCS AICS CHINA KECL 2-Methyl-3-isothiazolone P; S X - 220-239-6 - X X X X X Acetic acid X X - 200-580-7 - X X X X X Water X X - 231-791-2 - X - X X X 5-Chloro-2-methyl-3-isothiazolone P; S X - 247-500-7 - X X X X X Copper(4+), [[N,N',N'',N'''- [29H,31Hphthalocyaninetetrayltetrakis[meth ylenethio[(dimethylamino)methylid yne]]]tetrakis[n- methylmethanaminiumato]](2-)- N29,N30,N31,N32]-, tetrachloride X X - 251-705-7 - - X - - - Legend: X - Listed E - Indicates a substance that is the subject of a Section 5(e) Consent order under TSCA. F - Indicates a substance that is the subject of a Section 5(f) Rule under TSCA. N - Indicates a polymeric substance containing no free-radical initiator in its inventory name but is considered to cover the designated polymer made with any free-radical initiator regardless of the amount used. P - Indicates a commenced PMN substance R - Indicates a substance that is the subject of a Section 6 risk management rule under TSCA. S - Indicates a substance that is identified in a proposed or final Significant New Use Rule T - Indicates a substance that is the subject of a Section 4 test rule under TSCA. XU - Indicates a substance exempt from reporting under the Inventory Update Rule, i.e. Partial Updating of the TSCA Inventory Data Base Production and Site Reports (40 CFR 710(B). Y1 - Indicates an exempt polymer that has a number-average molecular weight of 1,000 or greater. Y2 - Indicates an exempt polymer that is a polyester and is made only from reactants included in a specified list of low concern reactants that comprises one of the eligibility criteria for the exemption rule. U.S. Federal Regulations TSCA 12(b) SARA 313 Component TSCA 12(b) 2-Methyl-3-isothiazolone Section 5 5-Chloro-2-methyl-3-isothiazolone Section 5 Component CAS-No Weight % SARA 313 - Threshold Values % Copper(4+), [[N,N',N'',N'''-[29H,31Hphthalocyaninetetrayltetrakis[methylenethio[(dimethylamino) methylidyne]]]tetrakis[n-methylmethanaminiumato]](2-)- N29,N30,N31,N32]-, tetrachloride 33864-99-2 <1 1.0 SARA 311/312 Hazardous Categorization Acute Health Hazard Chronic Health Hazard Fire Hazard Sudden Release of Pressure Hazard Reactive Hazard Yes Yes No No No Clean Water Act Component CWA - Hazardous CWA - Reportable CWA - Toxic Pollutants CWA - Priority Pollutants Substances Quantities Acetic acid X 5000 lb - - Page 7 / 9
Component CWA - Hazardous CWA - Reportable CWA - Toxic Pollutants CWA - Priority Pollutants Substances Quantities Water - 1 LB - - Copper(4+), [[N,N',N'',N'''-[29H,31Hphthalocyaninetetrayltetrakis[methyle nethio[(dimethylamino)methylidyne]]]t etrakis[n- methylmethanaminiumato]](2-)- N29,N30,N31,N32]-, tetrachloride - - X - Clean Air Act Not applicable OSHA Occupational Safety and Health Administration OSHA - Occupational Safety and Health Administration CERCLA This material, as supplied, contains one or more substances regulated as a hazardous substance under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA) (40 CFR 302) Component Hazardous Substances RQs CERCLA EHS RQs Acetic acid 5000 lb - California Proposition 65 This product does not contain any Proposition 65 chemicals. State Right-to-Know Component Massachusetts New Jersey Pennsylvania Illinois Rhode Island Acetic acid X X X - X Copper(4+), [[N,N',N'',N'''- [29H,31Hphthalocyaninetetrayltetrakis[ methylenethio[(dimethylamino )methylidyne]]]tetrakis[n- methylmethanaminiumato]](2- )-N29,N30,N31,N32]-, tetrachloride - - X - - U.S. Department of Transportation Reportable Quantity (RQ): DOT Marine Pollutant DOT Severe Marine Pollutant Y N N U.S. Department of Homeland Security This product does not contain any DHS chemicals. Other International Regulations Mexico - Grade No information available Canada This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all the information required by the CPR. WHMIS Hazard Class D2B Toxic materials E Corrosive material Page 8 / 9
16. Other information Prepared By Creation Date Revision Date Print Date Revision Summary Regulatory Affairs Richard Allan Scientific A Subsidiary of Thermo Fisher Scientific Tel: (800) 522-7270 27-Feb-2014 27-Feb-2014 27-Feb-2014 This document has been updated to comply with the US OSHA HazCom 2012 Standard replacing the current legislation under 29 CFR 1910.1200 to align with the Globally Harmonized System of Classification and Labeling of Chemicals (GHS). Disclaimer The information provided on this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered as a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other material or in any process, unless specified in the text. End of SDS Page 9 / 9