STATS WINDOW. INDUSTRY REVIEW AT A GLANCE Global Pharmaceutical Industry

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Volume 6, Issue 6, December 2013 STATS WINDOW The Pacific Business Review International has taken an initiative to start a section which will provide a snapshot of major Global & Indian economic indicators and industry review alternatively. A snapshot of the section in upcoming issues is hereunder: January 2013 February 2013 March 2013 April 2013 May 2013 June 2013 Economy at a Glance (Global & Indian) Automobile Industry (World): Statistical Review Economy at a Glance (Global & Indian) Healthcare Sector: Global Scenario Economy at a Glance (Global & Indian) Retail Sector: Global Scenario The current issue covers a brief overview of Global Pharmaceutical Industry. The data covers Medical Expenditure, Growth, Profitability, Pharmaceutical patents, sales, Global Pharmaceutical Market, Health financing, imports and Exports for World as well as for India. INDUSTRY REVIEW AT A GLANCE Global Pharmaceutical Industry The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals licensed for use as medications. Pharmaceutical companies are allowed to deal in generic and/or brand medications and medical devices. They are subject to a variety of laws and regulations regarding the patenting, testing and ensuring safety and efficacy and marketing of drugs. This research-based pharmaceutical industry makes a major contribution to the prosperity of the world economy. It is a robust sector that has been one of the pillars of industrialized economies and is increasingly recognized as an important sector in the developing world as well. It contributes to employment (direct, indirect, or induced), trade (through imports and exports), expenditure on research and development (R&D), and technological capacity building. It is also a necessary foundation for the existence of the generic industry. Data regarding the economic contribution of pharma industry has been provided. Also in particular, development of the Indian pharma sector and it's contribution to our economy is also provided. Populations in developed markets are increasingly aged and obese, driving spend in areas such as oncology and diabetes due to high prevalence; this effect is beginning to become apparent in European markets as well. In developed markets spending is concentrated in the top 20 classes to a much larger extent than in pharma emerging countries. 92 w w w. p b r. c o. i n

From the above table it is clear that Generics represent a larger share of the market in volume and value terms. Pharmaceutical spend in developed markets continue to be dominated by brands but Generics continue to dominate growth in spending in pharmerging markets. In high GNI countries medicine spend levels have been contained or reduced due to patent expiries and growing emphasis on utilization of generics, particularly for many of the chronic diseases treated in primary care. Spending level increases in high income countries are primarily driven by specialty medicines and diabetes treatments. In countries with income under $25,000 per capita, higher levels of spending growth will be driven by increased diagnosis and treatment rates and a change in the nature of the disease burden from acute to chronic disease. Governments in these countries are typically committed to expanding access to healthcare in their populations, although the implementation of this has often been slow. From the table it is evident that USA has highest number of patents due to better research and development facilities and higher technology. w w w. p b r. c o. i n 93

Volume 6, Issue 6, December 2013 These tables show that USA is the major research and development centre and manufacturer of medicines. Also USA and Europe has the largest pharmaceutical market. From the above table it is clear that major pharmaceutical companies have revenues from sales of pharmaceutical products that are lower than 50% of their total sales. Other products manufactured by these companies usually include medical devices, nutritional products, consumer healthcare products and products for animal health. Geographical headquarters of major pharmaceutical companies are approximately evenly distributed between the U.S. and Western Europe 94 w w w. p b r. c o. i n

Exhibit H Health financing w w w. p b r. c o. i n 95

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Volume 6, Issue 6, December 2013 Exhibit I Pharmaceutical sales 100 w w w. p b r. c o. i n

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Indian Pharma Sector The Pharmaceutical industry in India is the world's third-largest in terms of volume. India is now among the top five pharmaceutical emerging markets of the world. In terms of the global market, India currently holds a modest 1 2% share, but it has been growing at approximately 10% per year. India gained its foothold on the global scene with its innovatively engineered generic drugs and active pharmaceutical ingredients (API), and it is now seeking to become a major player in outsourced clinical research as well as contract manufacturing and research. Exhibit A Drugs and Pharmaceuticals: Growth and Profitability in the year 2010-11 The sector generates around 40 percent of its sales from exports. Pharma sector imports raw materials like 11 chemicals intermediates and active pharmaceuticals ingredients (APIs). Imports accounts for 38 percent of the overall raw material cost. A weak rupee will make imports costlier, resulting in a higher rise in raw material cost. w w w. p b r. c o. i n 107

Volume 6, Issue 6, December 2013 Exhibit B IMPORTS It may be observed that the imports shown declined in growth in pharmaceuticals products. As such imports are being resorted to on the year 2010-11 compared to previous year. The country is almost quality & economic considerations and not necessarily due to non - self-sufficient in production of most of formulations/ availability from domestic sources. Exhibit C EXPORTS The share of Exports of the Drugs Pharmaceuticals and Fine 4.20% during the period 2006- Chemicals in the total National Exports declined from 4.50% to 07 to 2010-11, 108 w w w. p b r. c o. i n

Exhibit D R&D spending of leading Indian and Global pharmaceutical MNEs Exhibit E Geographical Distribution of Pharma Companies These Indian states have been arranged in descending order of number of manufacturing units. It is noted that each of these five states account for more than 5 % of total number of pharmaceutical manufacturers in the country. w w w. p b r. c o. i n 109