Assisted Conception Unit, St James' University Hospital - Leeds

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Assisted Conception Unit, St James' University Hospital - Leeds Contact details Level 6, Gledhow Wing, St James' University Hospital, Beckett Street, Leeds, LS9 7TF Phone: Fax: Web: 113 26 5387 113 26 4812 www.leedsreproductivemedicine.co.uk Opening times 8. - 17. Monday to Friday. Weekends and Bank Holidays as necessary for egg collections, embryo transfers etc Patient enquiries Katherine Reddington - Administration Co-ordinator Person responsible Mrs Vinay Sharma NHS clinic but will also allow patients who are ineligible for NHS funding, or who require further unfunded cycles to pay for their treatment. Patients over the age of 42 were treated by this clinic during the reporting period. Treatments offered IVF, IUI, ICSI, DI Services offered IVF activities IVF, ZIFT, ICSI, treatment with donor gametes or donor embryos, partial surrogacy, full surrogacy. DI/GIFT/IUI activities DI, IUI w/partner sperm, natural cycle IUI/DI. Other information MESA, PESA, TESA, sperm assessment, cycle monitoring, ovulation induction, tubal surgery, other reproductive surgery, IUI for patients with psychosexual dysfunction Ovulation induction with IUI. Eligibility criteria relate to female age, relationship status, number of previous children, BMI. Donor recruitment Sperm donors recruited. Egg donors recruited. Centre accepts known donors, known donors used for known recipient, known donors entered into donor pool. Support services Independent counselling on/off-site. As many counselling sessions as required are included in cost of treatment. Dedicated counsellor, team approach. Storage activities Egg storage, sperm storage, embryo storage. Sperm stored from donors. Eggs/sperm stored from patients and for oncology patients. Embryos stored from donors and patients. Satellite centres Satellite IVF offered. Percentage of multiple births Percentage of embryos transfers (under 4 years) Live birth rate per IVF cycle (%) 45+ Singleton 1 Twin 2 4-42 Triplet 3 <35 25 5 75 1 25 5 75 1 25 5 75 1 Page 1 Centre 63

Assisted Conception Unit, St James' University Hospital - Leeds Summary success rates Live birth rates for IVF & ICSI embryo transfers using own eggs Percentage of ICSI (39%) vs IVF (61%) 4-42 26.5%(16/4) 25.2%(38/151) 19.3%(16/83) ++(7/46) ++(/11) ++(/3) 3.4%(16/349) 27.5%(38/138) 2.8%(16/77) ++(7/44) ++(/7) ++(/2) 2.2%(138/683) 18.2%(49/269) 15.1%(23/152) 8.2%(8/98) ++(/16) ++(/3) 21.8%(87/4) 19.9%(3/151) 13.3%(11/83) ++(7/46) 4.8%(19/4) 5.3%(8/151) 6.%(5/83) 4-42 22.4%(15/67) ++(9/21) ++(1/13) ++(2/1) ++(/1) 22.7%(15/66) ++(9/2) ++(1/13) ++(2/1) ++(/1) 14.%(18/129) ++(13/37) ++(1/23) ++(3/24) ++(/3) 19.4%(13/67) ++(6/21) ++(1/13) ++(2/1) 3.%(2/67) ++(3/21) * These figures include IVF, ICSI and PGS activities. Please refer to the HFEA web site "Find a clinic" page to see the PGS data which can be subtracted from the overall stats to obtain IVF & ICSI activities separately. Donor Insemination 35-39 4-42 Treatment cycles ++(4/34) ++(2/18) ++(/2) ++(/1) ++(4/34) ++(2/18) Treatments using donated eggs embryos embryos Key to symbols ++ Percentages are not calculated where there are fewer than 5 cycles, or live births are in each age category. Transfers ++(12/38) ++(1/7) No treatments carried out during the reporting period for this age category/treatment type. Page 2 Centre 63

CARE Sheffield Contact details 24-26 Glen Road, Sheffield, South Yorkshire, S7 1RA Phone: Fax: Web: 114 258 9716 114 255 4853 www.carefertility.com Opening times 8. - 17. Monday to Friday8. - 12. Saturday Patient enquiries Mrs Joanne Day - Patient Services Manager Person responsible Dr Adel Shaker Private clinic but will also offer treatment to patients funded by the NHS where a suitable contract exists. Patients over the age of 42 were treated by this clinic during the reporting period. Treatments offered IVF, IUI, ICSI, DI Services offered IVF activities IVF, ICSI, treatment with donor gametes or donor embryos, assisted hatching. DI/GIFT/IUI activities DI, IUI w/partner sperm. Other information PESA, TESA, sperm assessment, cycle monitoring, ovulation induction. Treatment information in other languages: Interpreters available for translation of written information and chaperoning. Eligibility criteria relate to female age, male age. Satellite centres Satellite IVF offered. Donor recruitment Sperm donors recruited. Egg donors recruited. Egg sharing. Centre accepts known donors, known donors used for known recipient, known donors entered into donor pool. Support services Independent counselling on-site. As many counselling sessions as required are included in cost of treatment. Centre holds patient information evenings. Named nurse system, team approach. Storage activities Egg storage, egg & ovarian tissue storage, sperm storage, embryo storage. Percentage of multiple births Percentage of embryos transfers (under 4 years) Live birth rate per IVF cycle (%) 45+ Singleton 1 Twin 2 4-42 Triplet 3 <35 25 5 75 1 25 5 75 1 25 5 75 1 Page 1 Centre 61

CARE Sheffield Summary success rates Live birth rates for IVF & ICSI embryo transfers using own eggs Percentage of ICSI (46%) vs IVF (54%) 4-42 36.2%(64/177) 3.%(27/9) 24.1%(14/58) ++(5/41) ++(1/11) ++(/2) 4.8%(64/157) 32.9%(27/82) 28.%(14/5) ++(5/35) ++(1/9) 28.6%(87/34) 19.9%(32/161) 16.1%(15/93) 9.8%(8/82) ++(1/21) 27.7%(49/177) 24.4%(22/9) 24.1%(14/58) ++(4/41) ++(1/11) 8.5%(15/177) 5.6%(5/9) ++(1/41) 4-42 ++(9/44) ++(4/29) ++(4/2) ++(2/1) ++(/4) ++(9/43) ++(4/29) ++(4/2) ++(2/1) ++(/3) 16.%(13/81) 9.1%(5/55) ++(6/37) ++(2/19) ++(/7) ++(9/44) ++(3/29) ++(4/2) ++(2/1) ++(1/29) * These figures include IVF, ICSI and PGS activities. Please refer to the HFEA web site "Find a clinic" page to see the PGS data which can be subtracted from the overall stats to obtain IVF & ICSI activities separately. Donor Insemination 35-39 4-42 Treatment cycles ++(3/19) ++(/4) ++(/2) ++(2/19) ++(1/19) Treatments using donated eggs embryos embryos Key to symbols ++ Percentages are not calculated where there are fewer than 5 cycles, or live births are in each age category. Transfers ++(16/47) ++(4/23) No treatments carried out during the reporting period for this age category/treatment type. Page 2 Centre 61

Centre for Reproductive Medicine and Fertility, Sheffield Contact details Jessop Wing, Sheffield Teaching Hospitals NHS Foundation Trust, Tree Root Walk, Sheffield, S1 2SF Phone: Fax: Web: 114 226 85 114 226 852 www.jessopfertility.org.uk Opening times 8. - 17. Monday to Friday. 8. - 14. Saturday Patient enquiries Val Kitcheman - Business Support Manager Person responsible Professor William Ledger NHS clinic but will also allow patients who are ineligible for NHS funding, or who require further unfunded cycles to pay for their treatment. Patients over the age of 42 were treated by this clinic during the reporting period. Treatments offered IVF, IUI, ICSI, DI, PGD Services offered IVF activities IVF, ZIFT, ICSI, treatment with donor gametes or donor embryos, assisted hatching, partial surrogacy, full surrogacy. DI/GIFT/IUI activities DI, IUI w/partner sperm, natural cycle IUI/DI, treatment facilities for patients with communicable viral infections. Other information PESA, TESA, PGD, sperm assessment, cycle monitoring, ovulation induction, tubal surgery, other reproductive surgery. Treatment information in other languages: Interpreters available Eligibility criteria relate to female age, male age, BMI. Satellite centres Service not offered. Donor recruitment Sperm donors recruited. Egg donors recruited. Egg sharing. Centre accepts known donors, known donors used for known recipient, known donors entered into donor pool. Support services Independent counselling on-site. As many counselling sessions as required are included in cost of treatment. Centre holds patient information evenings. Dedicated counsellor, team approach, female doctor available. Storage activities Sperm storage, embryo storage. Sperm stored from donors, from patients, for oncology patients. Embryos stored from donors and patients. Percentage of multiple births Percentage of embryos transfers (under 4 years) Live birth rate per IVF cycle (%) 45+ Singleton 1 Twin 2 4-42 Triplet 3 <35 25 5 75 1 25 5 75 1 25 5 75 1 Page 1 Centre 196

Centre for Reproductive Medicine and Fertility, Sheffield Summary success rates Live birth rates for IVF & ICSI embryo transfers using own eggs Percentage of ICSI (3%) vs IVF (7%) 4-42 3.5%(61/2) 2.5%(17/83) ++(6/37) ++(5/42) ++(/7) 33.2%(61/184) 22.7%(17/75) ++(6/34) ++(5/4) ++(/5) 25.3%(9/356) 14.3%(2/14) 17.9%(12/67) 8.6%(7/81) ++(/1) 21.5%(43/2) 19.3%(16/83) ++(5/37) ++(4/42) 9.%(18/2) 1.2%(1/83) ++(1/37) ++(1/42) 4-42 ++(16/45) ++(6/15) ++(1/9) ++(/1) ++(/3) ++(16/45) ++(6/15) ++(1/9) ++(/1) ++(/3) 25.3%(21/83) ++(8/29) ++(1/16) ++(/2) ++(/6) ++(12/45) ++(4/15) ++(1/9) ++(4/45) ++(2/15) * These figures include IVF, ICSI and PGS activities. Please refer to the HFEA web site "Find a clinic" page to see the PGS data which can be subtracted from the overall stats to obtain IVF & ICSI activities separately. Donor Insemination 35-39 4-42 Treatment cycles ++(18/45) 7.1%(4/56) ++(1/1) ++(/3) ++(/1) ++(17/45) 7.1%(4/56) ++(1/1) ++(1/45) Treatments using donated eggs embryos embryos Key to symbols ++ Percentages are not calculated where there are fewer than 5 cycles, or live births are in each age category. Transfers ++(/1) ++(5/18) No treatments carried out during the reporting period for this age category/treatment type. Page 2 Centre 196

Clarendon Wing - Leeds Contact details Reproductive Medicine Unit, C Floor Clarendan Wing, Leeds General Infirmary, Belmont Grove, Leeds, LS2 9NS Phone: Fax: Web: 113 392 6136 Reception 113 392 6662 www.leedsreproductivemedicine.co.uk Opening times 8. - 4. Monday to Friday Saturday and Sunday: 9. - no specific closing time, dependant upon bookings Patient enquiries Mandy Blackburn - RMU Secretary Person responsible Professor Adam Balen NHS clinic but will also allow patients who are ineligible for NHS funding, or who require further unfunded cycles to pay for their treatment. Patients over the age of 42 were treated by this clinic during the reporting period. Treatments offered IVF, IUI, ICSI, DI, GIFT, PGD Services offered IVF activities IVF, ZIFT, zona drilling, ICSI, treatment with donor gametes or donor embryos, partial surrogacy, full surrogacy. DI/GIFT/IUI activities DI, GIFT, IUI w/partner sperm, natural cycle IUI/DI. Other information MESA, PESA, TESA, PGD, sperm assessment, cycle monitoring, ovulation induction, tubal surgery, other reproductive surgery. Eligibility criteria relate to female age, relationship status, single women, same sex couples. Satellite centres Satellite IVF offered. Donor recruitment Egg donors recruited. Centre accepts known donors, known donors used for known recipient, known donors entered into donor pool. Support services Independent counselling on/off-site. As many counselling sessions as required are included in cost of treatment. Independent support group available:. Team approach, female doctor available. Storage activities Sperm storage, embryo storage, storage of materials from patients with communicable viral infections. Percentage of multiple births Percentage of embryos transfers (under 4 years) Live birth rate per IVF cycle (%) 45+ Singleton 1 Twin 2 4-42 Triplet 3 <35 25 5 75 1 25 5 75 1 25 5 75 1 Page 1 Centre 52

Clarendon Wing - Leeds Summary success rates Live birth rates for IVF & ICSI embryo transfers using own eggs Percentage of ICSI (43%) vs IVF (57%) 4-42 27.2%(143/526) 17.9%(45/251) 16.4%(24/146) 9.6%(9/94) ++(1/17) ++(/2) 3.9%(143/463) 2.1%(45/224) 18.9%(24/127) 11.3%(9/8) ++(1/14) ++(/2) 22.6%(24/91) 14.1%(61/434) 13.%(31/238) 9.6%(15/156) ++(1/25) ++(/4) 2.2%(16/526) 15.9%(4/251) 13.7%(2/146) 7.4%(7/94) ++(1/17) 7.%(37/526) 2.%(5/251) 2.7%(4/146) 2.1%(2/94) 4-42 18.6%(19/12) ++(11/46) ++(7/33) ++(2/14) ++(/4) ++(/1) 19.%(19/1) ++(11/45) ++(7/33) ++(2/14) ++(/4) ++(/1) 12.9%(25/194) 15.9%(14/88) 14.1%(9/64) ++(3/28) ++(/6) ++(/2) 14.7%(15/12) ++(1/46) ++(6/33) ++(2/14) 3.9%(4/12) ++(1/46) ++(1/33) * These figures include IVF, ICSI and PGS activities. Please refer to the HFEA web site "Find a clinic" page to see the PGS data which can be subtracted from the overall stats to obtain IVF & ICSI activities separately. Donor Insemination 35-39 4-42 Treatment cycles 22.1%(33/149) 13.3%(12/9) ++(1/13) 22.1%(33/149) 12.2%(11/9) 1.1%(1/9) ++(1/13) Treatments using donated eggs embryos embryos Key to symbols ++ Percentages are not calculated where there are fewer than 5 cycles, or live births are in each age category. Transfers ++(1/37) ++(6/21) No treatments carried out during the reporting period for this age category/treatment type. Page 2 Centre 52

Hull IVF Unit Contact details Hull and East Yorkshire Women and Children's Hospital, Hull Royal Infirmary, Anlaby Road, Hull, HU3 2JZ Phone: Fax: Web: 1482 382 648 1482 382 672 Opening times 8.3-16.3. With some evening clinics. 24Hr cover on-call. Patient enquiries Mrs Liz Robinson - Office Manager Person responsible Mr Stephen Maguiness Private clinic but will also offer treatment to patients funded by the NHS where a suitable contract exists. Patients over the age of 42 were treated by this clinic during the reporting period. Treatments offered IVF, IUI, ICSI, DI, GIFT Services offered IVF activities IVF, ZIFT, ICSI, treatment with donor gametes or donor embryos, partial surrogacy, full surrogacy. DI/GIFT/IUI activities DI, GIFT, IUI w/partner sperm, natural cycle IUI/DI. Other information MESA, PESA, TESA, sperm assessment, cycle monitoring, ovulation induction, tubal surgery, other reproductive surgery, Hycosy Tubal Patient Testing Eligibility criteria relate to female age, BMI, patients from abroad. Donor recruitment Egg donors recruited. Egg sharing. Support services Independent counselling on/off-site. As many counselling sessions as required are included in cost of treatment. Tours offered to patients before treatment. Dedicated counsellor, team approach. Storage activities Sperm storage, embryo storage. Sperm stored from donors, from patients, for oncology patients. Embryos stored from donors and patients. Satellite centres Service not offered. Percentage of multiple births Percentage of embryos transfers (under 4 years) Live birth rate per IVF cycle (%) 45+ Singleton 1 Twin 2 4-42 Triplet 3 <35 25 5 75 1 25 5 75 1 25 5 75 1 Page 1 Centre 21

Hull IVF Unit Summary success rates Live birth rates for IVF & ICSI embryo transfers using own eggs Percentage of ICSI (34%) vs IVF (66%) 4-42 24.4%(51/29) 23.6%(17/72) ++(3/31) ++(1/2) ++(/1) ++(/1) 28.8%(51/177) 27.4%(17/62) ++(3/27) ++(1/14) ++(/1) ++(/1) 2.%(7/35) 19.8%(23/116) 7.1%(4/56) ++(4/3) ++(/3) ++(/3) 19.1%(4/29) 15.3%(11/72) ++(2/31) ++(1/2) 5.3%(11/29) 8.3%(6/72) ++(1/31) 4-42 ++(3/15) ++(1/7) ++(1/6) ++(/2) ++(3/13) ++(1/7) ++(1/6) ++(/1) ++(6/25) ++(2/12) ++(1/11) ++(/2) ++(1/15) ++(1/7) ++(1/6) ++(2/15) * These figures include IVF, ICSI and PGS activities. Please refer to the HFEA web site "Find a clinic" page to see the PGS data which can be subtracted from the overall stats to obtain IVF & ICSI activities separately. Donor Insemination 35-39 4-42 Treatment cycles ++(1/22) ++(1/2) ++(/7) ++(1/22) ++(1/2) Treatments using donated eggs embryos embryos Key to symbols ++ Percentages are not calculated where there are fewer than 5 cycles, or live births are in each age category. Transfers ++(2/16) ++(/2) No treatments carried out during the reporting period for this age category/treatment type. Page 2 Centre 21