Centre for Ecology & Hydrology, Bush Estate, Penicuik, Midlothian, EH26 0QB b

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International Environmental Modelling and Software Society (iemss) 2012 International Congress on Environmental Modelling and Software Managing Resources of a Limited Planet, Sixth Biennial Meeting, Leipzig, Germany R. Seppelt, A.A. Voinov, S. Lange, D. Bankamp (Eds.) http://www.iemss.org/society/index.php/iemss-2012-proceedings Methods for the assessment of human health impacts from air pollution based on monitoring data, atmospheric dispersion model results and contextual data in Scotland S. Reis a, S. Steinle a, b, H. Cowie c, F. Hurley c a Centre for Ecology & Hydrology, Bush Estate, Penicuik, Midlothian, EH26 0QB b Geography, College of Life & Environmental Sciences, University of Exeter, Amory Building, Rennes Drive, Exeter, EX4 4RJ c Institute of Occupational Medicine, Research Avenue North, Riccarton, Edinburgh, EH14 4AP, UK Email: srei@ceh.ac.uk Abstract: High ambient concentrations of air pollutants, such as particulate matter (PM10, PM2.5), nitrogen oxides (NO x ) or ground-level ozone, occur in densely populated areas and thus have the potential for serious adverse human health effects. While statutory requirements for air quality monitoring due to national or European legislation defines the need for the operation of monitoring stations in particular in the densely populated urban areas, the spatial distribution of those sites is often not sufficient to adequately assess exposure to air pollutants for the whole population. The assessment of exposure to one or several air pollutants in an integrated manner has been described in Reis et al. (2005) for the European scale, however, the availability of high resolution data for Scotland allows for a more detailed assessment, in particular with regard to the socio-economic context. Atmospheric chemistry transport models (in short ACTMs) are useful tools to determine air quality across a wide range of spatial scales, from regional to local, with the availability of highly resolved (spatially as well as temporally) datasets to drive these models being a prerequisite. In this paper we discuss approaches for the integration of different datasets, such as stationary air quality monitoring data with ACTM model results (using the EMEP4UK model, Vieno et al., 2010), to estimate exposure of the Scottish population to ambient air pollutant concentrations. In addition, contextual information (e.g. a spatial representation of the Scottish Index of Multiple Deprivation, SIMD) and the latest land use data from the recently released CEH Land Cover Map 2007 allow us to derive enhanced, integrated data products for the quantitative assessment of human health effects. Finally, the paper discusses how the conceptual framework of a full-chain approach may be compromised by data availability and how impact assessments for human health and ecosystem health may be better integrated to improve the evidence base for policy action. Key Words: impact assessment, human health, ecosystem health, data integration 1. INTRODUCTION In the area of impact assessment, substantial advances in the development and application of quantitative models have been made in recent years. These modelling approaches have often built upon experiences from detailed, process-

based ecological models, which are in turn based upon observations and experiments and detailed datasets to establish model parameters. For human health impact assessment in particular, conceptual models representing a fullchain approach have been established for instance by the ExternE research project series (http://www.externe.info) and widely applied e.g. in the more recent HEIMTSA EU Integrated Project in the 6th Framework Programme (http://www.heimtsa.eu). These conceptual models aim to represent the full causal chain from the initial driver of a problem through to the effect. A key challenge in populating and driving quantitative models in this realm is the availability of and access to detailed datasets. In comparison to modelling ecosystem processes, observations on environmental state and pressures, as well as on exposure and effects on human health, are scarce. As a further complication, individual or cohort data are often restricted due to confidentiality issues, in particular when investigating specific sub-groups of a population. Finally, the purpose for which socio-economic statistical data or environmental indicators are routinely collected often determines the formats, which reflect administrative boundaries or political entities rather than categories or classifications suitable for modelling approaches. In this paper, we will discuss some of these challenges using the example of integrating data for quantitative spatio-temporal modelling of environmental determinants of human health effects in a case study for Scotland, with special reference to outdoor air pollution as a risk factor. 2. BACKGROUND Closely linked to the full chain approach noted earlier is the modified Driver- Pressure-State-Exposure-Effect-Action (in short, mdpseea) model depicted in Figure 1. This has been developed by Morris et al. (2006) by expanding the well established DPSIR (Driver-Pressure-State-Impact-Response) model widely applied by the European Environment Agency (EEA) in reporting indicators for health impacts. The introduction of a split between Exposure and Effect in DPSEEA takes account of an increased awareness in epidemiological research that what matters is not simply the state of the environment per se but exposure, understood as an individual s interactions with that environment. Modified DPSEEA emphasises context: the susceptibility of different individuals or groups to the same level of exposure can be substantially modified by contextual factors, as indeed can the levels and patterns of exposure itself. Intrinsic to the modified DPSEEA model is that it includes a response or action reflecting a remedial policy or regulatory activity (Figure 1). The modified DPSEEA model has a strong focus on human health impacts; however, similar approaches are being developed and applied in the frame of Ecosystem Services (ESS) research. Rounsevell et al. (2010) present a Framework for Ecosystem Service Provision (FESP) which builds on the DPSIR concept and illustrates how the socio-ecological (sub-)system is represented by the P-S-I-R part of the full chain. With the provision of services to humans as a central role of ESS, there are obvious links to be explored between human and ecosystem health impact assessments (Section 6). For our analysis here, we will present approaches to integrate data for quantitative modelling of the D-P-S part of the full chain, with some aspects of Context and Effect taken into account.

Figure 1. The modified DPSEEA model (Morris et al., 2006) presents an extension of the widely applied Driver-Pressure-State-Impact-Response (DPSIR) model (EEA, 2012), which in itself is an expansion of the OECD Pressure-State-Response (PSR) framework (OECD, 2012). The context reflects the socio-demographic and socioecological influences which, for a given state of the environment, may affect and individual s exposure or susceptibility. 3. EXPLORING THE DATA REALM In order to collect and process all datasets needed for impact assessment along the full chain, a range of different data sources have to be explored. For a full spatio-temporally resolved quantitative modelling approach, this requires identifying a suitable level of detail which can be obtained either directly from raw data, or by processing and transforming datasets with the help of surrogate information for their disaggregation. The following categories of data have been identified for the Scottish case study: Demographic data (population numbers by age and gender) Socio-economic indicators (e.g. the Scottish Index of Multiple Deprivation - SIMD) Environmental data (ambient air pollutant concentrations, both modelled and observed) Health effect data (e.g. prescription or asthma hospital admissions, National Health Service) Surrogate information (e.g. land-use and land-cover data, urban-rural classification) Demographic data are readily available for Scotland from the Scottish Government via the Scottish Neighbourhood Statistics (SNS, http://www.sns.gov.uk/). The degree of detail allows for a disaggregated representation of a range of sub-groups by age and/or gender. The best spatial resolution of SNS data publicly available is on Datazone (Datazones, or in short DZ, are a combination of Postcode areas and present the key small-area statistical geography unit for Scotland). Datazones represent administrative units rather than landscape features.

The Scottish Index of Multiple Deprivation is the socio-economic indicator (SIMD, http://www.scotland.gov.uk/topics/statistics/simd) used to identify small area concentrations of multiple deprivation aspects across Scotland in a consistent manner. The main aim of the SIMD is to allow effective targeting of policies and the allocation of funding taking account of areas with a high concentration of multiple deprivation factors. SIMD and other socio-economic data are available as well from SNS on Datazone (DZ) level, both for individual DZ ranks (representing the position of a DZ relative to all others for a specific indicator, such as SIMD Health or SIMD Housing, or an aggregate SIMD level). Environmental data used in this study originates from statutory monitoring network data (see http://www.scottishairquality.co.uk for a detailed description) and results from the application of atmospheric chemistry transport models (ACTMs). ACTMs provide detailed spatio-temporally highly resolved results of 3D concentration fields in for instance hourly resolution. Both monitoring network and modelled data are presented on grids of 1 1 km or 5 5 km resolution with different geographic projections. It should be noted that the monitoring network data is used to generate country-wide maps of annual average concentrations by interpolating between a relatively small number of monitoring stations, using road networks and other source-specific information to inform the spatial distribution of point measurements. Data on health effects are without doubt the most difficult to obtain. This is partly because of a general lack of complete and consistent data collection on total population level (availability) and partly because of confidentiality, with low numbers of cases at a high spatial resolution requiring the suppression of data to avoid the identification of individuals (accessibility). The latter issue is of particular importance when analysing environmental determinants of health effects of a population sub-group, such as children, where it was difficult to obtain spatiallyexplicit data with a sufficient disaggregation into different socio-economic categories. Surrogate information, for example land-use and land-cover information, is required for a meaningful spatial allocation of data. Data available on Postcode or Datazone level represents a distribution based on political or administrative spatial units. These administrative units are typically designed to comprise an approximately equal number of people and as can be seen in the left-hand representation of DZs in Scotland in Figure 2, their geographical size can vary substantially across the country. In order to generate maps of a spatial distribution of the population that is realistic, additional information is required. Land-cover information, for instance on built-up areas, can be used to constrain the distribution of DZ populations onto grid cells. Figure 2 depicts the data flow and approach taken to collate and integrate all datasets needed for the quantitative modelling approach. All datasets are processed to generate a 1 1 km grid which allows for both a detailed graphical display of different datasets and indicators in a consistent framework. In addition, the unifying spatial unit through the gridding process supports a meaningful statistical analysis of spatial correlations (air pollutant concentrations and asthma cases, most deprived areas and health outcomes and suchlike). On a technical level, this integration is realised using the Feature Manipulation Engine (FME, http://www.safe.com/) for data processing, collating and reprojection and ArcGIS 10 (http://www.esri.com/software/arcgis/arcgis10) for visualisation and analyses.

S. Reis et al. / Analysing implications of assessing human health impacts from air pollution based on Figure 2. Representation of data flow and integration steps required for an integrated analysis of demographic, socio-economic, health and environmental data in Scotland. 4. GENERATING INTEGRATED DATA PRODUCTS Figure 3. Population density and spatial distribution for Scotland (left) derived from SNS population statistics for 2010 (resolution 2 1 1 km, based on DZ level information) and zoom in to the Central Belt with Glasgow in the West and Edinburgh in the East (above) The following figures illustrate the different data products being ingested and processed to derive the final gridded datasets for analysis. Figure 3 displays the population distribution for Scotland, based on the 2010 data from Scottish Neighbourhood Statistics (SNS). Figure 4 shows the interpolated maps generated on the basis of the Scottish air quality network monitoring stations and using data from the UK National Emission Inventory (NAEI) to enhance the spatial distribution, reflecting major emission sources such as road networks and large point sources.

Figure 4. Nitrogen Dioxide (NO 2 ) concentrations from the Scottish Air Quality Network (http://www.scottishairquality.co.uk/) for 2010 (left) and a projection for 2020 (right) (Units: µg m -3 ). Both Figures 3 and 4 demonstrate the significant differences in population density and air quality due to the spatial structure of major settlements and general population distribution between the central belt and the East coast and the rest of the country, including the sparsely populated highlands. In Figure 5, three different variants of the Scottish Index of Multiple Deprivation (SIMD) are displayed. By directly comparing the ranks for Health with the global SIMD rank, variations in causes for deprivation can be identified. The SIMD is used for a wide range of purposes e.g. as a statistical classification and can serve as an indicator to target resource allocation and policy development for small areas. Figure 6 presents a spatial overview of bronchodilator prescription data for the years 2010/11 for children aged 0-9, i.e. the target age-group for the Scottish Government Good Places, Better Health prototype (http://www.scotland.gov.uk/topics/health/good-places-better-health/recommendations) for which the major part of this work has been conducted. While DZ level information is roughly comparable due to the similar population numbers, a comparison on a grid level (see Figure 7) will yield a more robust basis to identify hotspots and potentially underlying causes by looking at air quality and deprivation information. The prescription data is derived from datasets provided by the Information Services Division (ISD) (a part of National Health Service Scotland), with aggregation levels ensuring that no confidential information (i.e. small numbers of individual cases) can be identified. Finally, two examples for derived and combined data mapping products illustrate the added value of integrating environmental, health and socio-economic datasets (Figure 7). One application, for instance, is the ex-ante impact assessment of policies aiming at reducing future air pollutant concentrations, here displayed by comparing projected 2020 annual mean concentrations of nitrogen dioxide with current levels (Figure 7, top), weighted with 2010 population levels. A further integration with socio-economic information, such as the SIMD, provides an opportunity to identify hotspot areas, where air quality and deprivation may lead to the exacerbation of respiratory diseases (Figure 7, bottom). Such analyses can aid the development of targeted interventions in relevant policy areas.

S. Reis et al. / Analysing implications of assessing human health impacts from air pollution based on Figure 5. Spatial distribution of Scottish Index of Deprivation (SIMD) ranks across Scotland in 2007. The overall SIMD rank (left) and the ranks for health (right) show distinctly different spatial patterns, indicating substantial differences in deprivation and contextual aspects for instance between urban and rural areas. A higher rank (darker colour) indicates more deprived areas (lighter colours correspond to less deprived areas). Figure 6. Spatial distribution of health indicator data - here an example for Bronchodilator prescriptions for children aged 0-9 for the years 2010/11 on Datazone (DZ) level for the whole of Scotland (left) and a zoom into the Edinburgh area (above).

Figure 7. Derived maps for the analysis of future air quality impacts (top) for Scotland's central belt and illustrating the combination of air quality, health and deprivation data (bottom). The top map depicts the spatial distribution of population exposure changes due to the difference in annual mean concentrations of NO 2 in 2020 compared to current levels in 2010, multiplied by the population size in each 1 1 km 2 grid cell. Darker shades indicate larger reductions, whereas red cells reflect increases in NO 2 concentrations in 2020 (population numbers have been kept constant at 2010 levels. The bottom map shows a combination of air quality (annual mean concentrations of NO 2 in 2010 from Scottish Air Quality), health (hospital admissions due to respiratory disease, SNS) and deprivation (SIMD rank). Such combinations of datasets provide a basis for further analysis and allow for deriving comprehensive indicators for correlations between environmental, health and socio-economic data.

5. CONCLUSIONS AND OUTLOOK The conclusions for the work described in our paper can be split into two main aspects. On the one hand, we describe the methodology and approach to integrate a wide range of data products into a common structure for the quantitative modelling of environmental determinants of public health in Scotland. And while the technical side of this step is relatively straightforward, issues of data availability and accessibility have the potential to seriously impede progress in this area. The full-chain approach and the modified DPSEEA model indicate well how the whole analysis framework relies on the ability to quantitatively model and assess each step. A general scarcity of data on health effects, for instance, may mean that a quantitative assessment beyond the Exposure step is impossible, ultimately leading to a lack of evidence for the development or assessment of policy action. In a similar way, data for and the understanding of exposure assessment requires substantial efforts, as current approaches to combining information on annual ambient concentrations at the home location of the general population do not adequately reflect the variability of personal exposure in space and time (see Steinle et al., 2012, this volume). A second aspect indicated in the Introduction is that full-chain approaches have traditionally focused on human health impact assessment. However, recent developments in the area of Ecosystem Services (ESS) research indicate that there are opportunities to bring both impact assessment streams closer together. Figure 8 illustrates how both human health and ecosystem effects are caused by the same or similar drivers and how policy actions often affect both - either as synergies, or unintended negative consequences. This implies that there is a substantial overlap as well with regard to the data required to conduct assessments of either human or ecosystem impacts. Concepts such as socio-ecology and human ecology could provide a basis for the methodological development of more integrated and streamlined approaches which combine both environmental and public health effects Figure 8. Illustration of a concept for a common frame-work for human and ecosystem health impact assessment (HIA), incorporating Ecosystem Services (ESS) (provisioning, regulating, supporting and cultural services) which may affect different stages of the full chain.

6. ACKNOWLEDGMENTS This work is supported by the project Environmental Determinants of Public Health in Scotland (EDPHiS, http://www.edphis.org), funded by the Scottish Government's Rural and Environment Science and Analytical Services Division (RESAS), and the LIAISE Network of Excellent, funded under the 7 th Framework Programme of the European Commission. The authors would like to thank the Good Places, Better Health Intelligence Partnership and colleagues of ISD Scotland for their support in identifying and sourcing relevant datasets. 7. References European Environment Agency (EEA) (2012) Glossary entry for DPSIR, http://glossary.eea.europa.eu/eeaglossary/d/dpsir (last access11/03/2012). Morris GP, Beck SA, Hanlon P, Robertson R. (2006) Getting strategic about environment and health. Public Heath 120, 889-907. Morris, GP (2012) Ecological public health and climate change policy. Perspectives in Public Health 130(1), 27-33, doi:10.1177/1757913909355221. Special Issue on Climate Change. Organisation for Economic Co-operation and Development (OECD) (2012) Glossary entry for the Pressure-State-Response (PSR) Framework, http://stats.oecd.org/glossary/detail.asp?id=2105 (last access11/03/2012). Reis S, Nitter S, Friedrich R (2005) Innovative Approaches in Integrated Assessment Modelling of European Air Pollution Control Strategies Implications of Dealing with Multi-pollutant Multi-effect Problems. Environmental Modelling and Software 20 (12), 1524-1531. Rounsevell MDA, Dawson TP, Harrison PA (2010) A conceptual framework to assess the effects of environmental change on ecosystem services. Biodiversity and Conservation 19, 2823-2842, DOI:10.1007/s10531-010-9838-5. SNS Scottish Neighbourhood Statistics, http://www.sns.gov.uk/ (last access 03/05/2012) Scottish Air Quality, http://www.scottishairquality.co.uk/index.php (last access 03/05/2012) Vieno M, Dore AJ, Stevenson DS, Doherty R, Heal MR, Reis S, Hallsworth S, Tarrason L, Wind P, Fowler D, Simpson D and Sutton MA (2010) Modelling surface ozone during the 2003 heat-wave in the UK, Atmospheric Chemistry & Physics 10, 7963-7978, DOI:10.5194/acp-10-7963-2010.