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Final Agenda; Rev 18 June 2015 Subject to late changes, as necessary European Summer Symposium 25-28 June 2015 AXICA Conference Center Berlin, Germany Program Chairs: Planning Committee: Prof. H. Burkhard Dick MD Arthur B. Cummings, MD A. John Kanellopoulos MD Prof. Michael C Knorz MD Prof. Dan Reinstein MD Mr. Rolf Schwind John A Vukich MD THURSDAY, 25 JUNE 18:30 20:30 AECOS Reception and Exhibits FRIDAY, 26 JUNE 07:30 Exhibits and coffee 08:30 AECOS OPENING SESSION Welcome and Update on AECOS Europe Michael C Knorz MD President, AECOS Europe 08:37 The History of AECOS John A Vukich MD President, AECOS Americas 08:43 SESSION 1: AECOS INNOVATION FORUM Moderators: Michael Knorz MD, William Link PhD Panel: Lucio Buratto MD, Armin Scharrer MD, Rolf Schwind Investing in Ophthalmology: Current Trends 08:44 Where is venture capital investing today? William Link PhD 08:52 Trending today: Practice Acquisitions Armin Scharrer MD 09:00 Where is private equity investing? Mr. Thom Rasche 09:08 Discussion Latest Innovations from Industry 09:18 ZEPTO device for CCCL Mr. John Hendrick 09:30 PiXL: Early Results from a Prospective Clinical Trial Matthias Elling MD

09:42 Mechatronic IOLs Georg Bretthauer MD 09:54 AcuTarget for Tear Film Assessment Roger Zaldivar MD 10:06 ARGOS Intraocular Pressure Measuring following Cataract Surgery Hagen Thieme MD 10:18 Update on PowerVision s Novel FluidVision Accommodating IOL Barry Cheskin 10:30 Break 11:00 Innovations in Cornea Keynote: New Developments in Corneal Imaging and Surgery Claus Cursiefen MD Innovations in the Treatment of Dry Eye Panel: Tal Raviv MD, Sathish Srinivasan MD, Miguel Teus MD, Roger Zaldivar MD 11:12 Keynote: New Technologies for Identifying and Treating Dry Eye Arthur Cummings MD 11:22 Tear Film Osmolarity and Dry Eye Sathish Srinivasan MD 11:29 Eyelid Thermal Pulsation for Dry Eye Tal Raviv MD 11:36 Highlights of the HD Analyzer Roger Zaldivar MD 11:38 The role of tear osmolarity in post- cataract dry eye Miguel Teus MD 11:44 Panel discussion 12:00 Lunch 12:20 13:30 Lunchtime Symposium See Life to the Max: Innovations in Cataract and Refractive Surgery Brought to you by AMO 13:40 SESSION 2: PRESBYOPIA CORRECTION Moderators: Francesco Carones MD, Burkhard Dick MD 13:50 Keynote: Presbyopia - Are we meeting patient expectations? Gerd Auffarth MD 14:00 Small Aperture IOL John Vukich MD 14:07 Bioanalogic Intraocular Lens Pavel Stodulka MD 14:14 Pharmaceutical Interventions for Presbyopia John Doane MD 14:21 Discussion

Presbyopia Case Presentations Panel: Gerd Auffarth MD, John Kanellopoulos MD, Aylin Kilic MD 14:30 Case 1: Corneal Inlays for Presbyopia Correction Arthur Cummings MD 14:45 Case 2: IOLs for Correction of Presbyopia Matteo Piovella MD 15:00 Case 3: Laser Vision Correction for Presbyopia Michiel Luger MD 15:15 Discussion: Are we meeting patient expectations? 15:30 Break SESSION 3: WHAT I HAVE CHANGED IN THE PAST 12 MONTHS & WHY Panel: Francesco Carones MD, Burkhard Dick MD, Erik Mertens MD, Wolfgang Riha MD, 15:50 EDOF IOLs to Implement my Portfolio of Options Francesco Carones MD 15:57 Lens Material Burkhard Dick MD 16:04 Changes I have made as a result of Physician CEO Wolfgang Riha MD 16:11 Combined cataract and glaucoma surgery made easy Erik Mertens MD 16:18 Discussion All SESSION 4: TODAY S CLINICAL CHALLENGES Moderator: Prof. Manfred Tetz MD 16:25 Dysphotopsia Opening Discussion: Prevailing opinions on dysphotopsia Manfred Tetz MD 16:33 Negative dysphotopsia (incidence and solutions) Shmuel Levinger MD 16:41 Positive dysphotopsia (incidence and solutions) Gerd Auffarth MD 16:49 Final Discussion: Conclusions on management of dysphotopsia Manfred Tetz MD Techniques & Technologies 17:07 Vitreolysis: Yag laser, intravitreal injection or vitrectomy Anselm Jünemann MD 17:15 How do we measure the back surface of the cornea? John Kanellopoulos MD 17:23 Discussion 17:30 AECOS Adjourns

SATURDAY, 27 JUNE 07:30 Exhibits and coffee SESSION 5: Moderators: MICRO- INVASIVE GLAUCOMA SURGERY Steven Vold MD, Dan Reinstein MD, Manfred Tetz MD 08:30 MIGS Concurrent with Cataract Surgery Herbert Reitsamer MD 08:36 MIGS as a Stand Alone, Early Intervention Anselm Jünemann MD 08:42 Implantable Drug Delivery Devices for Improved Patient Compliance Steven Vold MD 08:48 Discussion SESSION 6: INNOVATIONS IN CORNEAL CROSS- LINKING Panel: John Marshall PhD, Michael Mrochen MD, William Trattler MD 09:00 Keynote: Interaction of UV Light with the Cornea Marco Lombardo MD 09:12 Case 1: Modified Protocols John Kanellopoulos MD 09:24 Case 2: Innovations in Drug Delivery which Affect CXL Michael Mrochen MD 09:36 Case 3: Photorefractive Intrastromal Cross- Linking for Therapeutic Use 09:48 Case 4: PACK- CXL for the Treatment of Corneal Infiltrates and Early Ulcers Andreas Behndig MD Farhad Hafezi MD 10:00 SESSION 7: YOUNG OPHTHALMOLOGISTS SESSION Moderators: Arthur Cummings MD, William Link PhD Panel: Victor Derhartunian MD, Mike Holzer MD, Stephanie Joachim MD, Wolfgang Riha MD, Alain Saad MD 10:10 Introduction/Presentation of the 2015 AECOS European Research Award 10:45 Break Panel Discussion: Issues facing young ophthalmologists as they begin practice in Europe 11:00 SESSION 8: TECHNOLOGIES ON TRIAL Judge: The Honorable John Marshall, PhD Jury Panelists: Arthur Cummings MD, Burkhard Dick MD, Erik Mertens MD, John Kanellopoulos MD 11:05 Femto Cataract is not necessary Ekkehard Fabian MD Femto is the future of cataract surgery Michael Knorz MD 11:25 LASIK, yes! SMILE is not yet ready Miguel Teus MD SMILE: The Future is Here Dan Reinstein MD

11:45 Multifocal IOLs vs Extended Depth of Focus Lenses: The Case for Multifocal IOLs The Case for Extended Depth of Focus Lenses Why These Options Will Not Work 12:05 Corneal Inlay vs Monovision LASIK: Inlays have too many side effects Inlays are safe and effective Matteo Piovella MD Manfred Tetz MD Thomas Neuhann MD Mike Holzer MD John Vukich MD 12:30 Wrap up; adjourn for Lunch 12:50 14:00 Lunchtime Symposium Shaping Tomorrow s Vision: Zeiss Innovative Refractive Solutions Brought to you by Carl Zeiss Meditec 14:10 Joseph Colin Award Lecture: Ophthalmic Applications with Google Glass and Wearable Devices Lucio Buratto MD 14:20 SESSION 9: INTEGRATED SURGICAL PLATFORMS: The Business Case for Premium Technologies in Cataract Surgery Moderator: William Link PhD, Burkhard Dick MD 14:22 Experience in AMO's advanced solutions in Premium Cataract Surgery Ahmed Assaf MD 14:29 Benefits of the Integrated Cataract and Refractive Suite Nicholas Batra MD 14:36 Advantages of an all- laser lens and refractive surgery platform Erik Mertens MD 14:43 Advances in femtosecond cataract surgery with the LENSAR platform William Trattler MD 14:50 Femto LDV Z8 Christian Rathjen PhD 14:57 Will integrated surgical platforms deliver better outcomes in cataract surgery? First key findings around the world William Culbertson MD 15:04 Discussion Audience votes: Yes No Too Early To Know Will integrated surgical platforms deliver better outcomes in cataract surgery? Will integrated surgical platforms drive procedure growth in the premium channel? 15:10 Break

SESSION 10: VIDEO GRAND ROUNDS Interactive Presentations on Difficult Cases Moderator: Lucio Buratto MD (max 7 min videos + discussion) 15:30 Opaque IOL on the retina when all goes wrong in one second Pavel Stodulka MD 15:40 Shaking through 1.6 Roger Zaldivar MD 15:50 Complicated DMEK Cases Alain Saad MD 16:00 Challenges in Toric IOL Alignment William Trattler MD 16:10 Polyfocal IOLs and the femtosecond laser : a winning team Erik Mertens MD 16:20 VHF digital ultrasound epithelial mapping with digital subtraction pachymetry for trans- epithelial photo- therapeutic keratectomy Dan Reinstein MD 16:30 Discussion 16:40 SESSION 11: EUROPEAN REGULATORY UPDATE Moderators: Arthur Cummings MD, John Marshall PhD Panel: Miguel Bernabeu Dirk Muehlhoff Rolf Schwind David Tanzer MD 16:45 EU Post- Market Device Surveillance Michael Mrochen MD 16:50 Intro: AECOS European Regulatory Forum John Marshall PhD Interactive Panel & Audience Discussion 17:30 AECOS Adjourns 19:00 AECOS Reception and Awards Dinner (AXICA Centre) - Presentation of the Joseph Colin Award SUNDAY, 28 JUNE 07:30 Exhibits and coffee 08:30 The Birth of LASIK Lucio Buratto MD 08:40 SESSION 12: LATE BREAKING NEWS! Moderators: Thomas Kohnen MD, Erik Mertens MD 08:42 The cause of prostaglandin release in LCS Tim Schultz MD 08:49 Thermage blepharoplasty using radio frequency stimulation Matthias Elling MD

08:56 iray Therapy for AMD Reinhard Pichl MD 09:03 Discussion: Will these late breaking innovations have a future? 09:15 SESSION 13: LAMELLAR REFRACTIVE SURGERY: HOW DO WE REVIVE THE MARKET? Moderators: Arthur Cummings MD, Michael Knorz MD Panel: Victor Derhartunian MD, Jörn Jörgensen MD, Dan Reinstein MD 09:18 Snapshot of the Refractive Surgery Market in Europe Today Erik Mertens MD 09:25 Current Trends in the US LVC Market John Doane MD 09:32 New Devices for Essential Corneal Screening Dan Reinstein MD 09:39 Wavefront- guided, wavefront- optimized, topography driven: Criteria for choosing the optimal approach Arthur Cummings MD 09:46 Can new technologies such as SMILE evoke a renaissance in LVC? Jörn Jörgensen MD How to market, set patient expectations, etc. 09:53 LASIK vs IOL: Where is the limitations criteria? Should AECOS lead the development of pan- European guidelines? Thomas Kohnen MD 10:00 Discussion 10:30 Break 11:00 SESSION 14: MY BEST MARKETING INVESTMENT/MY WORST MARKETING MISTAKE Moderators: Jörn Jörgensen MD, Erik Mertens MD 11:02 Bad Press: Utilizing social media to effectively diffuse Erik Mertens MD 11:09 Critical website strategies for SEO and Reputation Management Onur Birsen MBA 11:16 The All Premium Practice: Is it sustainable? Omid Kermani MD 11:25 Panel Discussion: My Worst Marketing Mistake in the Past 3 Years My Best Marketing Decision in the Past 3 Years 11:45 Research vs Clinic vs Surgery Time: How do you balance? Example in a European Practice Arthur Cummings MD Example in a US Practice Steven Vold MD 12:00 Discussion SESSION 15: CLOSING SESSION: FEMTO AND BEYOND 12:15 Femto Applications: What tomorrow might bring Holger Lubatschowski PhD

12:22 Femto Lasers: Still at the dawn of an era Christian Rathjen PhD 12:29 LENSAR Streamline: A Femto Laser Swiss Army Knife Carlos Buznego MD 12:36 Future with Schwind Lasers Pavel Stodulka MD 12:43 SMILE and Beyond Dirk Muehlhoff 12:50 AMO s Advances in Cataract and Refractive Surgery David Tanzer MD 12:57 Cataract Refractive Outcomes: The Next Frontier Laurent Attias 13:04 Discussion 13:11 Closing Comments Michael Knorz MD Arthur Cummings MD 13:30 AECOS Adjourns