CURRICULUM VITAE. Franz Schaefer, M.D.



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CURRICULUM VITAE Franz Schaefer, M.D. ADDRESS: BORN: Center for Pediatrics and Adolescent Medicine Division of Pediatric Nephrology Im Neuenheimer Feld 430 69120 Heidelberg, Germany Phone:+49-6221-563-2396 Fax: +49-6221-56-5166 Email: franz.schaefer@med.uni-heidelberg.de June 14, 1961, Aschaffenburg, Germany EDUCATION: 1980-86 University of Würzburg Medical School 1984-85 Department of Neurosurgery, University of Würzburg M.D. degree (magna cum laude) 11-1986 National Medical Graduate Examination 1988/89 Foreign Medical Graduate Examination in the Medical Sciences 1998/99 Postgraduate Course Quality Management in Medicine Dept. of Medical Informatics, University of Heidelberg INTERNSHIPS: 1985-86 Department of Surgery, Charing Cross Hospital, London, Department of Neurology, University of Bern, Switzerland Department of Internal Medicine, District Hospital Langenthal, Switzerland RESIDENCY/SUBSPECIALTY TRAINING: 11-1986 to 6-1987 Municipal Children s Hospital Aschaffenburg, Germany 7-1989 to 4-1995 University Children s Hospital Heidelberg, Germany RESEARCH FELLOWSHIP: 7-1987 to 7-1989 Pediatric Nephrology and Endocrinology University of Heidelberg, Germany (Professor Karl Schärer) LICENSURE: 11-23-1986 National Licence of Physicians, Federal Republic of Germany Landesärztekammer Bayern

CERTIFICATION: 8-24-1994 Diplomate in Pediatrics 1-30-1999 Diplomate in Medical Quality Management 2006 Diplomate Hypertensiologist DHL by German Hypertension League 2007 Board Certification in Pediatric Nephrology RESEARCH SCHOLARSHIPS: 10-1987 to 2-1988 Department for Growth and Development, Institute of Child Health, London (Professor M.A. Preece) 10-1992 to 2-1993 and 11-1995 Division of Endocrinology and Metabolism, University of Virginia, Charlottesville, Va. (Prof. J.D. Veldhuis) 10-1999 to 9-2000 Departments of Medicine and Molecular Pharmacology, Stanford University (Profs. R. Rabkin and R.A. Roth) ACADEMIC APPOINTMENTS: 4-27-1995 Associate Professor of Pediatrics, Heidelberg University 12-20-2001 Professor of Pediatrics, Heidelberg University PROFESSIONAL/ADMINISTRATIVE APPOINTMENTS: 4-1995 Consultant, General Pediatrics and Pediatric Nephrology 10-2004 Head, Pediatric Nephrology Division, Heidelberg University Children s Hospital 4-2005 Director, KfH Kidney Center for Children and Adolescents, Heidelberg 2001-present DRG Coordinator, University Children s Hospital 2004-present Quality Management Coordinator, University Children s Hospital 2004-2006 Professional Leadership Training, University Hospital Heidelberg PROFESSIONAL SOCIETY MEMBERSHIPS: 1989 International Paediatric Nephrology Association 1990 Gesellschaft für Nephrologie 1990 European Dialysis and Transplant Association 1991 Gesellschaft für Kinderheilkunde 1991 European Society for Paediatric Nephrology 1992 European Society for Paediatric Research 1994 International Society for Peritoneal Dialysis 1995 Pediatric Nephrology Working Group 1995 Pediatric Endocrinology Working Group 2004 International Pediatric Hypertension Association

PROFESSIONAL COMMITTEE ACTIVITIES: 1995-1998 Steering committee, German Research Foundation Postgraduate College Experimental Kidney and Hypertension Research, Heidelberg 1998-1999 Medical Thesis Reviewing Board, Heidelberg University 1999-present 1999-present European Pediatric Peritoneal Dialysis Working Group ISPD Ad Hoc Committtee for Peritonitis Treatment in Children 2002/3 Council Member, German Working Group for Pediatric Nephrology (APN) 2003-present Council Member, European Society for Pediatric Nephrology (ESPN) 2006-2009 Council Member, International Pediatric Hypertension Association (IPHA) 2006-2010 Council Member, International Society for Peritoneal Dialysis (ISPD) 2007-present Council Member, International Pediatric Nephrology Association (IPNA) 2007-2008 Pediatric Nutrition Work Group Member, Kidney Disease Quality Initiative (KDOQI) 2008-2011 Acute Kidney Injury Work Group Member, Kidney Disease Improving Global Outcomes (KDIGO) 2008-present Head, joint working group for pediatric hypertension of Society for Pediatric Hypertension (GPN) and German Hypertension League (DHL) 2008-present Member of Ad Hoc Committee, European Society of Hypertension (ESH) for clinical practice guideline development in pediatric hypertension 2009-present Coordinator, ESPN-ERA/EDTA European Pediatric Renal Replacement Therapy Registry 2010-present Council Member, Center for Rare Diseases, University Hospital Heidelberg 2011-present Secretary, ERA-EDTA Workgroup for inherited Kidney Disorders 2011-present Member, WHO Pediatric Nephrology Topic Advisory Group for ICD-11 development REVIEWING AND EDITORIAL ACTIVITIES: Regular reviewing activities for: Journal of Pediatrics, Pediatric Research, European Journal of Pediatrics, Acta Paediatrica, Pediatric Nephrology, Peritoneal Dialysis International, American Journal of Kidney Diseases, Kidney International, Nature Clinical Practice Nephrology, Nephrology Dialysis Transplantation, Journal of the American Society of Nephrology, BMC Nephrology, American Journal of Physiology, International Journal of Obesity, American Journal of Transplantation, PLOS One 1999-2001 Editorial Board member, Pediatric Nephrology 1999-present Editorial Board member, Peritoneal Dialysis International 2002-2009 Associate Editor, Pediatric Nephrology 2005-present 2006-present 2007-present Editorial Board member, Current Pediatric Reviews Editorial Board member, BMC Nephrology Pediatric Section Editor, Nephrology Dialysis Tranplantation

2009-present 2011-present Editorial Board member, Clinical Nephrology Editorial Board member, Nature Reviews Nephrology CONSULTING ACTIVITIES: 2006-present 2007-present Consultant/Scientific Advisory Board member re. pediatric drug development for: Novartis, AstraZeneca, Boehringer Ingelheim, Bristol Myers Squibb, Otsuka, Akela, Takeda, Mitsubishi Pharma, Amgen, Alexion, Bayer, Genzyme, Shire, Astellas Visiting Consultant to Ped. Nephrology unit, Dubai Hospital, UAE HONOURS AND AWARDS: 1990 Best Abstract Award, Annual Meeting European Society for Pediatric Research, Vienna, Austria 1991 Travel Award, Annual Meeting European Dialysis Transplantation Association, Rimini, Italy 1994 Jürgen-Bierich Prize, Pediatric Endocrinology Working Group (coauthor) 1996 Travel Award, International Congress of Endocrinology, San Francisco 1997 Baxter Health Care Prize for Pediatric Peritoneal Dialysis Research 1998 von Recklinghausen Prize, German Endocrine Society 1998 International Who s Who in Medicine 1998 Kröner-Fresenius Prize, Pediatric Nephrology Working Group (coauthor) 1998 Best Pediatric Abstract Award, International Peritoneal Dialysis Meeting, Seoul, Korea 2000 Jürgen-Bierich Prize, Pediatric Endocrinology Working Group (coauthor) 2001 Best Scientific Abstract Award, 31 st International Symposium on GH and Growth Factors in Endocrinology and Metabolism, Malta 2001 2002 Baxter Health Care Prize for Pediatric Peritoneal Dialysis Research 2002 (senior author) 2003 Kröner-Fresenius- Prize, Pediatric Nephrology Working Group (senior author) 2005 International Society of Peritoneal Dialysis Award 2005 (senior author) 2006 IBM Faculty Award for Innovations 2006 Honorary Doctoral degree (Doctor honoris causa), State Medical University Tbilisi, Georgia 2009 International Society of Peritoneal Dialysis Award 2009 (senior author) 2010 Best Poster Award, European Society of Hypertension Meeting, Oslo 2010 Top Publication Award, Heidelberg University Hospital (50,000 )

CLINICAL RESEARCH NETWORK ACTIVITIES: 1987-1997 Coordinator, Cooperative Study Group on Puberty in Chronic Renal Failure 1993-2000 Founder and Coordinator, European Study Group for Pediatric Peritoneal Dialysis 1997-present Coordinator, European Study Consortium for Chronic Kidney Disorders Affecting Pediatric Patients (ESCAPE Network) 2001-2005 Co-Founder and Coordinator, International Pediatric Peritonitis Registry 2007-present Initiator and leader of International Pediatric Peritoneal Dialysis Network (consortium of 80 pediatric dialysis units, www.pedpd.org) 2008-present Initiator and coordinator of ERA-Net European research project PodoNet for clinical and experimental research into podocyte disorders 2008-present Initiator und Coordinator of European Cardiovascular Complications in Children with Chronic Kidney Disease ( 4C ) Study CLINICAL TRIAL EXPERTISE: 1992-1996 Investigator for the European Study on Pubertal Development in Children with Chronic Renal Failure 1998-2007 Lead Investigator, European Study Group for Blood Pressure Control and Progression of Chronic Renal Failure in Children (ESCAPE Trial) 2004 Lead Investigator, BIOKID Trial 2006-2009 Global Lead Investigator, CINCH Trial (Atacand in children with hypertension), AstraZeneca 2007-2009 Global Lead Investigator, Valsartan and Enalapril in Children with Hypertension Trial, Novartis 2007-2010 Lead Investigator, Hypertension in Pediatrics (HIP) Trial, AstraZeneca 2008-2009 German Lead Investigator, DOLPHIN Trial (Mircera dose finding in hemodialyzed children), Roche 2010-present German Lead Investigator, Rasilez (Aliskiren) Trial, Novartis ORGANISATION OF INTERNATIONAL SCIENTIFIC MEETINGS: since 2001 Pediatric Program Committee member, Annual Dialysis Conference, USA 2003 Co-President, Joint Annual Meeting of Arbeitsgemeinschaft Pädiatrische Nephrologie/Société Nephrologie Pediatrique, Strasbourg 2004 Seventh Symposium on Growth and Development in Children with Chronic Kidney Disease, Heidelberg 2004 Program Committee member, ISPD Congress, Amsterdam 2005 Scientific Committee President, Annual Meeting of European Society of Pediatric Nephrology, Istanbul 2006 Program Committee member, ISPD Congress, Hong Kong 2007 Program Committee Member, International Pediatric Nephrology Association, New York 2010

2008 Elected Scientific Committee President, International Pediatric Nephrology Association, Shanghai 2013 Since 2008 Regular International Symposia New Frontiers in Pediatric Nephrology, Heidelberg PUBLISHING ACTITIVITIES: 189 original publications in peer reviewed journals, including New Engl J Med, Lancet, Nature Medicine, J Clin Invest, Circulation 73 review articles 73 book chapters including 7 book editorships > 500 published abstracts Cumulative impact factor score: 937 H-Index: 38