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Nursing Best Practice for the Stroke Patient Complication Prevention Tara Panazzolo, MSN, RN-BC Nursing Performance Improvement Advisor Hackensack University Medical Center New Jersey State Stroke Conference April 2 nd, 2015

Financial Disclosure Statement I have no relevant financial relationships to disclose.

Learning Objectives Translate quality improvement opportunities into viable solutions to improve patient outcomes Discuss three major areas in which patients experience complications due to the side effects of stroke Falls Venous thromboembolism (VTE) Catheter Associated Urinary Tract Infections (CAUTI)

Stroke Leading cause of disability Consequences can be physical, cognitive and/or psychological Due to deficits, patients are at higher risk for falling, developing a venous thromboembolism, and/or a catheter associated urinary tract infection

Falls after Stroke 14-65% of stroke patients fall while in the hospital Up to 73% fall in the first six months post discharge Stroke patients are four times more likely to sustain a fracture Falls can occur at any stage Acute Rehabilitative Chronic Fall risk increases related to the severity of the stroke

Attributable Factors Stroke-related motor, sensory and visual deficits: Decreased strength/deconditioning Sensory loss Visual/balance deficits Incontinence Hemineglect Inattention Impairments prior to stroke Repeat fallers Care should be planned around these factors to minimize the risk of a fall

Preventing falls in these patients can: Prevent injury (ranging from minor to major or death) Improve quality of life Decrease fear of falling Decrease likelihood of activity restriction Overall better patient outcomes

Literature Review Limited studies Varying in sample size Studies related to falls are performed at varying time frames post stroke (i.e. one week versus six months) Limited evidence on interventions to reduce falls in this population Few studies in the acute care setting showed falls to occur during the day in the patient s room or bathroom/toilet Similar was found to be true for inpatient rehabilitation settings

Fall Prevention Post Stroke Systematic review/meta-analysis revealed Vitamin D to be effective in reducing fall rates and percentages Large majority of published intervention studies examined the effects of supervised exercise but could not directly correlate with fall reduction Other methods discussed in the literature Medications to alleviate symptomatology Environmental and/or assistive technology Social environment Sunlight exposure

General Fall Prevention Interventions Utilizing a fall risk assessment tool Ongoing assessment for existing and new risk factors Exercise to increase balance and strength Technology Bed or chair sensors/alarms Video monitoring Wireless connectivity and alerts to staff Fall alert identification Non-skid socks/slippers/shoes Focused rounding Proactive toileting Maintain a safe environment Call bell and belongings within reach PT/OT/ST evaluation and treatment

Venous Thromboembolism (VTE) VTE is a blood clot that forms, in a vein breaks loose and travels in the blood Results from a combination of hereditary, acquired risk factors, vessel wall damage, venoustasis and increased activation of clotting factors VTE includes both deep vein thrombosis (DVT) and pulmonary embolism (PE) DVT is a condition when a blood clot forms in a deep vein of the body PE is a blockage of the main pulmonary artery of the lung or one of it s branches by a substance that has travelled from elsewhere in the body through the blood stream Preventable cause of death and morbidity in hospitalized patients 20-42% of hospitalized stroke patients have been diagnosed with a VTE

Attributable Factors Age Immobility Possible dehydration Comorbidities: Malignancies Heart failure Atrial fibrillation

VTE Prevention in Ischemic and Hemorrhagic Stroke Patients Evidenced-Based risk assessments should be conducted upon admission to the hospital Initiation of prophylaxis in high risk patients Non-pharmacological Early ambulation Elastic compression stockings Intermittent pneumatic compression Pharmacological Antiplatelet agents Anticoagulants Procedural Inferior vena cava filter

VTE Prevention in Ischemic and Hemorrhagic Stroke Patients Early ambulation May be restricted Poor efficacy in prevention of VTE Elastic compression stockings Do not significantly reduce VTE risk Associated with skin breakdown Intermittent pneumatic compression Routinely utilized CLOTS 3 trial showed Intermittent Pneumatic Compression (IPC) application to immobile stroke patients is safe and reduces the risk of DVT and it s symptomatology Pharmacological Increased risk of bleeding complications Inferior vena cava filter No clear guideline May be considered to prevent PE in stroke patients with DVT

Stroke VTE Safety Recommendations for Ischemic and Hemorrhagic Stroke Patients Physician-Patient Alliance for Health & Safety recommends: Assess and document risk factor assessment on all stroke and rule out stroke patients Mechanical and pharmacological therapy is required for stroke core measures unless documented as contraindicated Ambulation progression Mechanical prophylaxis Intermittent pneumatic compression Venous foot pump Anti-embolism stockings Chemical prophylaxis UFH LMWH Reassess and document Prior to any procedure Change in patient s condition Continue appropriate prescribed therapy upon transfer or discharge

Catheter-Associated Urinary Tract Infections (CAUTI) CAUTI is the #1 healthcare acquired infection (HAI) Representing as much as 80% of HAIs Leading cause of secondary nosocomial bloodstream infections In July 2011, The Joint Commission (TJC) announced a new National Patient Safety Goal (NPSG) for 2012 for CAUTI surveillance Identified by the Centers for Medicare and Medicaid Services as a preventable condition this reimbursement will not be received for it s treatment

Center For Disease Control (CDC) CDC defines a CAUTI as a urinary tract infection with: an indwelling urinary catheter in place for >2 calendar days on the date of the infection one of the following symptoms Fever >100.4 Suprapubic tenderness Costovertebral angle pain or tenderness Urine culture with no more than two species of organisms, at least one of which is a bacteria of 10 5 CFU/ml Approximately 75% of hospital acquired UTIs are associated with a urinary catheter The most important risk factor is prolonged use of urinary catheter

CAUTI in Stroke Patients Most frequent complication of stroke 1-24% of patients develop a UTI within the 1 to 4 weeks post stroke Extend hospital stay Worsen stroke outcomes Increase cost of care There is limited research specific to Foley catheter related UTIs for stroke patients

Attributable Factors Double odds of acquiring a urinary tract infection than general medical/surgical patients Immunosuppression Brain injury may initially cause both local and systemic inflammation Possible systemic signaling of lymphoid organs Increased bladder dysfunction in 29%-58% of patients Urinary incontinence Urinary retention Aphasia, cognitive impairment, and severe functional impairment are independently associated with bladder dysfunction Increased likelihood of having an indwelling urinary catheter due to: Characteristics of a stroke patient Speech dysfunction and altered mental status alter means of communicating the need to void Limited mobility

CAUTI Prevention Post Stroke Reduce urinary catheter usage Insert urinary catheters based ONLY on defined CDC criteria: Acute urinary retention (sudden and painful inability to urinate or bladder outlet obstruction) To improve comfort for end-of-life care if needed Critically ill and need for accurate measurements of I&O (i.e. hourly monitoring) Selected surgical procedures (GU surgery/colorectal surgery) To assist in healing open sacral or perineal wound in the incontinent patient Need for intraoperative monitoring of urinary output during surgery or large volumes of fluid or diuretics anticipated Prolonged immobilization (potentially unstable thoracic or lumbar spine, multiple traumatic injuries such as pelvic fractures)

CAUTI Prevention Post Stroke Ensure individuals inserting catheters have been properly trained Insert catheters utilizing sterile technique/bundles Maintain a closed drainage system Maintain unobstructed urine flow Avoid dependent loops Perform perineal care at least twice daily and after each bowel movement Leave catheters in place only as long as required Daily discussion of removal of catheter Maintain hand hygiene and follow standard infection control precautions Prophylactic antibiotic utilization Utilize maintenance bundles

Next steps, upon discontinuation of urinary catheter: Develop individualized toileting plan with interdisciplinary input (prompted voiding, use of commodes, etc.) Use external catheters Hourly rounding with proactive toileting Bladder scan/straight catheterization as necessary for retention

REFERENCES Batchelor, F., Hill, K., Mackintosh, S., Said, C. (2010). What works in falls prevention after stroke? Retrieved from http://stroke.ahajournals.org/content/41/8/1715/full. Batchelor, F., Mackintosh, S., Said, C., Hill, K. (2012). Falls after stroke. International Journal of Stroke, 7(6), 482-490. Crespo-Diaz, J. (2014). Implementation and Sustainment of Hospital-Wide Evidence Based Practice Bundles to Prevent Catheter Associated Urinary Tract Infections. Clinical Key. 42 (6), 21-22. Dennis, M., Sandercock, P., Reid, J., Graham, C., Forbes, J., Murray, G. (2013). Effectiveness of intermittent pneumatic compression in reduction of risk of deep vein thrombosis in patients who have had a stroke (CLOTS 3): a multicentre randomised controlled trial. Lancet, 382, 516-524. Physician-Patient Alliance for Health & Safety Stroke VTE Safety Recommendations. Retrieved from http://www.ppahs.org/ob-vte-safety-recommendations-pdf/. Poisson, S., Johnston, C., Josephson, A. (2010). Urinary Tract Infections Complicating Stroke Mechanisms, and Possible Solutions. Retrieved from https://stroke.ahajournals.org/content/41/4/e180.full. Consequences, Surveillance Requirements for CAUTI Retrieved from http://www.jointcommission.org/standards_information/jcfaqdetails.aspx?standardsfaqid=442&programid=47. Urinary Tract Infection (Catheter-Associated Urinary Tract Infection (CAUTI) and Non-Catheter-Associated Infection (UTI) and Other Urinary System Infection Events. (2015) Retrieved from http://www.cdc.gov/nhsn/pdfs/pscmanual/7psccauticurrent.pdf. Urinary Tract