Curriculum Vitae Prof. Dr. Bruno Gottstein



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Curriculum Vitae Prof. Dr. Bruno Gottstein Name: Bruno Gottstein Born: 22 March 1954 Academic and Professional Career since 1992 Ordinarius in Veterinary and Medical Parasitology, University of Berne, Switzerland 2004 CBA (Certificate in Business Administration), Universities of Fribourg and Trier, Germany 2004 AssEVPC (European Veterinary Parasitology College) 1991 Habilitation (Privatdozent) in Veterinary and Medical Parasitology, University of Zurich, Switzerland 1989 Research Sabathical (to Dr. T.E. Nash), Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, Md, USA 1984-1985 Post-graduate Research Stay (to Dr. P.M. Schantz), Helminthic Diseases Branch, DPD, CID, Centers for Disease Control, Atlanta, USA 1981-1992 Research and senior research assistant (to Prof. J. Eckert), Institute of Parasitology, University of Zurich, Switzerland 1981 Ph.D., University of Bern, Switzerland 1

1979 Diploma in Medical Microbiology 1974-1979 Study of Medical Microbiology, University of Bern, Switzerland Project coordination, Membership in collaborative research projects (Selection 2001-2012) 2009-2012 Research Grant, for Echinococcus multilocularis and alveolar echinococcosis: the molecular struggle, from the Swiss National Science Foundation, prolongation project No. 3100AO-111780 2008-2010 Research Grant, for Molecular and epidemiological invetigations on Naegleria fowleri and other neurotropic free-living amoebae. FOCP-Project 2007-2009 Research Grant, for Toxoplasma gondii: Prevalences and Sources of infection in Switzerland, from the Swiss Federal Veterinary Office 2006-2009 Research Grant, for Echinococcus multilocularis and alveolar echinococcosis: the molecular struggle, from the Swiss National Science Foundation, project No. 3100AO-111780/1 2006-2008 Research Grant, for Development of a risk based surveillance program for Trichinella spp. in domestic swine and wildlife in Switzerland, from the Swiss Federal Veterinary Office 2005-2009 Research Grant, for Assessment of efficacy and efficiency of toltrazuril-treatment in newborn mice from Neospora-positive dams, from Bayer Animal Health 2004-2006 Research Grant, for The parasite-host interplay in alveolar echinococcosis (larval infection with Echinococcus multilocularis) ; from the Swiss National Science Foundation, project No. 31-63615.00 (2001-2004); bonus of excellence 2003-2009 Research Grant, for GCP study for the evaluation of serological tools to assess efficacy of toltrazuril-treatment in newborn calves from Neospora-positive dams, from Bayer Animal Health 2

2003-2005 Research Grant, for Development and evaluation of diagnostic tools to identify infectious stages for the study of horizontal transmission risks in ruminant neosporosis, toxoplasmosis and sarcocystiosis (COST 854), from the BBW, Project No. 00.0498 [EU No. QLK2-CT-2001-01050] 2003-2004 Research Grant, for GCP study on the comparative evaluation of different time schedules for the metaphylactic treatment of Echinococcus multilocularis in dogs, from Novartis Animal Health Inc. 2003-2005 Research Grant, for Epidemiologische Untersuchungen zur wirtschaftlichen Bedeutung von Neospora caninum beim Rind und zur epidemiologischen Bedeutung beim Hund in der Schweiz; Neo 03-05, from the Swiss Federal Veterinary Office, Project no. 973.105/1.03.06 2002-2003 Research Grant, for Treatment and assessment of disease in human alveolar echinococcosis. Novartis Foundation No. 01A04 2002-2005 Research Grant, for Protozoal reproduction losses in farm ruminants. COST-854, from the BBW, project No. Project No. BBW C01.0122 2001-2006 Research Grant, for EchinoRisk: Risk assessment and prevention of alveolar echinococcosis, from the BBW, Project No. 00.0586-1 [EU No. QLK-CT-2001-01995] 2001-2005 Research Grant, for Development of molecular tools to diagnose Naegleria fowleri and other neurotropic free-living amoebae. GR-Project No. 4500303638 2000-2003 Institutional Partnership Grant, for Public health impact of zoonoses, (consortium grant with PD Dr. N. Müller and Prof. Dr. R. Kurdova), from the Swiss National Science Foundation, project No. 7 IP 62584 Functions in Scientific Societies and Committees (Selection) since 2010 Member of the Human Rights Committee of the Leopoldina National Academy of 3

Sciences since 2009 Board-member of the Executive Board of the Vetsuisse Veterinary Public Health Institute 2009-2012 Board-member of the German Society for Parasitology since 2000 Expert for the Swiss Accreditation Services (SAS) for the accreditation of Swiss medical and veterinary diagnostic laboratories (ISO 17025) 1999-2006 President of the Swiss CASS-Commission for Polar Research 1990-1993 President of the Swiss Society of Tropical Medicine and Parasitology (SSTMP) since 1999 President of the Hans-Sigrist-Foundation for the promotion of Science at the University of Bern, Switzerland since 2004 Associate Member of the European Veterinary Parasitology College 1990-1994 Board-member (representative for Europe), World Association of Parasitology since 1994 since 1994 Delegate (representative for Switzerland, SSTMP), World Association of Parasitology Delegate (representative for Switzerland, SSTMP), European Federation of Parasitology Honours and Awarded Memberships (Selection) 2012 Honory Professor, University of Franche-Comté, France 2006 Member of the German Academy of Sciences Leopoldina 2004 Honorary Member of the Bulgarian Society of Parasitology 1993 Behring Bilharz Award 1989 Promotion Prize of the Swiss Society of Microbiology, Switzerland 4

Major Scientific Interests Selection of 3 key papers related to the main research projects: Spiliotis M, Mizukami C, Oku Y, Kiss F, Brehm K, Gottstein B. Echinococcus multilocularis primary cells: improved isolation, small-scale cultivation and RNA interference. Mol Biochem Parasitol. 2010; 174:83-7. Gottstein B, Wittwer M, Schild M, Merli M, Leib SL, Müller N, Müller J, Jaggi R. Hepatic gene expression profile in mice perorally infected with Echinococcus multilocularis eggs. PLoS One. 2010; 5:e9779. Mejri N, Müller J, Gottstein B. Intraperitoneal murine Echinococcus multilocularis infection induces differentiation of TGF-β-expressing DCs that remain immature. Parasite Immunol. 2011; 33:471-82. 5