GE Healthcare. UNICORN 5.2 vs 5.11. Software Change Description



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GE Healthcare UNICORN 5.2 vs 5.11 Software Change Description

Software change description: UNICORN 5.2 vs 5.11 Software change description: UNICORN 5.2 vs 5.11 Introduction This document describes the changes implemented in UNICORN 5.2 compared to the previous version 5.11. Note: Reference numbers are noted for each change. These numbers are used by GE Healthcare staff if additional information is requested concerning the change. UNICORN 5.2 has been verified for the following operative systems: Windows XP SP3 Windows Vista Business 32-bit EN SP1 Note: For installation in a Windows Vista environment, the AB edition (or later editions) of the UNICORN 5.2 software shall be used. UNICORN 5.2 has been verified for use with the following controller units: CU-950 CU-960 User documentation The user documentation for UNICORN 5.1 is also valid for UNICORN 5.2. The documents are Getting Started with UNICORN 5.1, UNICORN 5.1 User Reference Manual and UNICORN 5.1 Administration and Technical Manual. Different versions are available for specific applications, for example BioProcess or Oligo synthesis. New items Security and audit items Function added to enable notification by E-mail when unauthorized use of a password is detected. 382953499-R625 If signature acknowledgement of a message, question or manual instruction fails due to the use of an incorrect password an entry will be added to the global audit trail and a notification E-mail will be sent. 387170437-R625 Manual commands during a method run can now be signed electronically. 383628210- R625 Logbook entries will now show who is in control of the system during a method run. 387075130-R625 OPC functions The OPC server is now able to support virtual output. 385354883-R625 Software Change Description 28-9436-30 Edition AC 3

Software change description: UNICORN 5.2 vs 5.11 The OPC server is now able to retrieve the ID of the user in control of a system and the current batch ID from a running method. 385264148-R625 Warnings and alarms emerging from the valve check block are now handled correctly by the OPC Server. 396929096-R625 ÄKTAxpress An ÄKTAxpress system setup may now be changed. 381033068-R625 Updated or improved functions Security and audit items Audit trail entries are now accurate when data is recovered from CU-950/CU-960. 256639548-A264 The correct path is now used when verifying access rights. 256733837-M245 Users with access only to the Evaluation module can now log on and access the module without problems. 317533762-M264 Audit trails will now filter out response errors from excluded components. 334467145- N152 Audit trails will not include entries for changes that have not been performed. 343272560- P452 Previously, when a user account was disabled after too many logon errors, the user was only allowed a single logon attempt after the account was re-enabled by the system administrator. This is now corrected and three attempts are allowed. 319691187-R625 UNICORN Manager The countdown timer bar function in the UNICORN Manager module has been adjusted to properly display the time. 366684252-R625 Printer selection in the UNICORN Manager will not cause the module to terminate. 379582530-R625 The Access Group selection Tune has been removed from the User Setup. 384922223- R625 Data in disabled entry fields of the User Setup (Advanced edit) will no longer be validated in error. 246336434-M450 Method Editor Long column names will not cause a problem when a column is imported to the column list. 290489163-M264 The number of decimals for pressure values in the Column list is now presented properly. 335408366-R625 4 Software Change Description 28-9436-30 Edition AC

Software change description: UNICORN 5.2 vs 5.11 The Method Editor will not terminate if a method with an invalid message instruction is used. 344311770-M264 Problems with method queue start times between 12:00 and 12:59 AM and PM have been corrected. 350637029-R625 The values for variables connected to pause instruction break points may now be updated without causing method errors. 380000170-R625 Previous versions allowed the creation of a too long, invalid method by pasting extra blocks into the method. This is no longer possible. 318314540-C340 When using the instruction New_Chromatogram to create several chromatograms with the same name, only the curves from the first chromatogram were available for evaluation instructions. All curve data for the subsequent chromatograms with the same name was lost. This is now corrected. 322391048-T453 System Control The UNICORN applications will continue to respond if the server connection fails during the end of a method run. 247049328-F622 A Method Queue may now be started without disturbing the creation of results from a scouting run. 280986816-L536 The pressure unit may now be changed without causing errors in the displayed minimum, maximum and average values of the pressure curve. 313655321-R625 When pausing a manual run all curve activity, including expand curve(s), will now be set to pause. 321938582-O264 Digital signatures of questions at method start will now include date and time. 382440871-R625 Digital signatures of messages during a method run will now include date and time. 383041332-R625 The process picture has been improved to solve rare problems at the end of method or manual runs where the system state was not reflected correctly. The process picture now shows the correct state for all components at the end of the run. 389083387-L536 Evaluation The result files will now be numbered correctly when a scouting method is run. 246343947-L545 The function to adjust retention zero to the injection point will now apply also to printed reports. 247465988-E453 Result files containing only a single fraction mark may now be used with the Pool Fraction function. 256459010-A264 Any available folder may now be selected as the target folder for an export from the Multifile Peak Compare Wizard. 262142405-T453 Software Change Description 28-9436-30 Edition AC 5

Software change description: UNICORN 5.2 vs 5.11 Baseline editing can now be performed on calculated baselines on any peak integrated curve without causing the edited baseline to refer to curve number 01 instead of the curve selected for peak integration. 292484328-T453 PDF files can now be created from UNICORN and saved in any accessible folder without disturbing the operation of the UNICORN application. 292819756-T453 The Evaluation module will still respond if a pooled fraction curve is overwriting a fraction curve that has been used to create a pool table, which is then added to a pooling protocol. 322542121-T453 The Cut Curves function can now be applied to fraction, logbook and injection curves. 329814444-T453 Curve names longer than 127 characters (including number, result file and chromatogram names) will no longer cause the Evaluation module to terminate. 330251168-T453 Files can no longer be deleted from the Copy to External dialog. 331451187-N152 Fraction instruction variable values will now be shown correctly in evaluation reports. 352274566-N152 The chromatogram header information is now handled properly when the function Open Chromatograms to Compare is used. 379595401-T453 Snapshots can be printed from other chromatograms than the first chromatogram. 381206173-T453 The highest value of the index number that is added as an appendix to the name of a result file each time result data with the file name is added has been increased from 20 to 100. 383106506-T453 Methods containing questions, that are exported from a result file, will no longer include the answers in the exported method. 388460807-R625 The subscript characters in the V 0 /V t field of the Integrate dialog are now visible at all times. 385028925-T453 Oligo Oligo synthesis data with many characters will no longer cause the Evaluation module to close during printing. 297664377-P352 ÄKTAxpress The method wizard has been improved in order to perform faster. 387941111-R625 6 Software Change Description 28-9436-30 Edition AC

For local office contact information, visit www.gelifesciences.com/contact GE Healthcare Bio-Sciences AB Björkgatan 30 751 84 Uppsala Sweden www.gelifesciences.com GE, imagination at work and GE monogram are trademarks of General Electric Company. UNICORN, BioProcess and ÄKTAxpress are trademarks of GE Healthcare companies. UNICORN: Any use of this software is subject to GE Healthcare Standard Software End-User License Agreement for Life Sciences Software Products. All third party trademarks are the property of their respective owners. 2008-2009 General Electric Company All rights reserved. First published Sep. 2008 All goods and services are sold subject to the terms and conditions of sale of the company within GE Healthcare which supplies them. A copy of these terms and conditions is available on request. Contact your local GE Healthcare representative for the most current information. GE Healthcare UK Ltd Amersham Place, Little Chalfont, Buckinghamshire, HP7 9NA, UK GE Healthcare Bio-Sciences Corp 800 Centennial Avenue, P.O. Box 1327, Piscataway, NJ 08855-1327, USA GE Healthcare Europe GmbH Munzinger Strasse 5, D-79111 Freiburg, Germany GE Healthcare Bio-Sciences KK Sanken Bldg. 3-25-1 Hyakunincho, Shinjuku-ku, Tokyo 169-0073, Japan imagination at work 28-9436-30 AC 01/2009