An Initial Presentation of Flank Pain Caused by Thoracic Disc Herniation



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Thoracic disc herniation 221 An Initial Presentation of Flank Pain Caused by Thoracic Disc Herniation Jiun-Lang Su 1, Wei-Chean Tan 2, Chih-Chung Chao 1, Chung-Ming Tsai 3, Chao-Hsin Wu 1 Symptomatic thoracic disc herniation is less common than herniation in the cervical or lumbosacral regions, and has no characteristic or obvious neurological disability at first presentation. This increases the difficulty of an early diagnosis. Patients often experience an extensive workup and/or invasive procedures targeting other disorders before diagnosis. We present a case involving a 48-year-old male who came to our emergency room with a chief complaint of flank pain. Thoracic disc herniation was finally diagnosed in less than one day after an abdominal computed tomography scan at our emergency room due to highly alertness of our emergency doctor. The patient recovered after discectomy with miniopen transforaminal lumbar interbody fusion. No more flank pain has occurred postoperatively. Key words: thoracic disc herniation, flank pain, miniopen transforaminal lumbar interbody fusion Introduction Herniation of an intervertebral disc of the thoracic spine is relatively rare compared to a similar event in the cervical or lumbosacral region and only account for 0.25% to 0.75% of all symptomatic herniated discs (1-3). Unlike cervical or lumbar disc herniation, thoracic disc herniation (TDH) has no typical characteristics and even no obvious neurological disabilities at first presentation. In this article, we describe an adult man who complained of flank pain and was eventually diagnosed with TDH at our emergency room (ER) in less than 24 hour. Case Report A 48-year-old man visited our ER with his chief compliant being severe left flank pain for four days. The pain had undergone a sudden onset, consisted of sharp sensations, was persistent and radiated to left groin area. The visual analogue scale pain score was ten. The pain became worse with movement, especially when getting up and turning his body. Resting did not relieve his pain. Only anterior bending could slightly decrease the discomfort. The pain was associated with cold sweating and sometimes scrotum tenderness. An earlier attack with similar episode had happened one month prior to admission while he was in China. His occupation was that of head of a mechanical factory, and he had been traveling a lot between Taiwan and China. During the earlier episode, after resting and analgesic administration for several days, the tenderness had subsided, but flank pain had progressed despite local treatment in Received: May 13, 2010 Accepted for publication: July 29, 2010 From the 1 Department of Emergency Medicine, 2 Department of Neurosurgery 3 Department of Medical Image, Chung Shan Medical University Hospital, Chung Shan Medical University, Taichung, Taiwan Address reprint requests and correspondence: Dr. Chao-Hsin Wu Department of Emergency Medicine, Chung Shan Medical University Hospital 110 Section 1, Chienkuo North Road, South District, Taichung City 40201, Taiwan (R.O.C.) Tel: 0937552593 Fax: (04)23248108 E-mail: chaohsinwu@hotmail.com

222 J Emerg Crit Care Med. Vol. 21, No. 4, 2010 China. Thus, he had returned to Taiwan and visited our ER. In addition to the above, falling down one week earlier was mentioned. Tracing his past history, he had received extracorporeal shock wave lithotripsy for a right renal stone. At our ER, the patient s body temperature was 36.6ºC, his pulse rate was 70/min, his respiratory rate was 18/min, and his blood pressure was 151/101 mmhg. The back was straight without deformity and the range of motion was not limited. The straight leg raising test and Patrick test were negative. Exogenital examination showed no redness, swelling, discharge, tenderness or mass. Neurological examinations, including muscle power, sensory sensation, and deep tendon reflex, were all within normal limits. The laboratory testing revealed a white blood cell count of 7920 /mm 3 (67.6% segmented neutrophil, 27.0% lymphocytes and 3.3% monocytes), hemoglobin of 16.4 g/dl and a platelet count of 248,000 /mm 3 ; furthermore, the biochemistry results were all within the normal range. Kidney, Ureter, Bladder (KUB) x-rays and routine urine analysis were negative. Renal sonography also showed no apparent hydronephrosis. During observation at the ER, Ketorolac (30 mg) and Tramadol (100 mg) were administered, but symptoms were only relieved slightly. Abdominal computed tomography (CT) was performed due to the unusual flank pain and a high suspicion of herniated intervertebral disc disease between T12 and L1 was the result (Fig. 1). A neurosurgical doctor was consulted and thoracic-lumbar spine magnetic resonance imaging (MRI) was arranged to provide a definite diagnosis (Fig. 2). Under the impression of herniated intervertebral disc of the T12-L1 region with left L1 radiculopathy, the patient was admitted and received discectomy with miniopen transforaminal lumbar interbody fusion. An extruded disc with compression of the left L1 root was found intraoperatively (Fig. 3). The patient had an uneventful postoperative course and now has a symptom-free life. Discussion Although the incidence of symptomatic TDH is around one per million per year (1), asymptomatic TDH accounts for 37% of herniations Fig. 1 Abdominal CT transverse view showing T12-L1 disc herniation

Thoracic disc herniation 223 Fig. 2 T2 weight image of the sagittal MRI demonstrating findings consistent with T12-L1 disc herniation Fig. 3 The extruded disc was removed during the operation

224 J Emerg Crit Care Med. Vol. 21, No. 4, 2010 in the general population by magnetic resonance imaging scanning (4). However, in comparison with herniations of lumbar or cervical intervertebral discs, symptomatic TDH is comparatively rare; this is because the adjacent structure of the thoracic spine provides relatively good stability (5). Nevertheless, the pathogenesis of TDH is not well defined. According to the literature, it may be multifactoral and linked to trauma (6), Scheuermann s disease (7), degenerative back (5) and genetic factors (8). In addition, sportsmen such as golfers and soccer players are reported to suffer from TDH (2,9). In these circumstances, the earlier fall and an occupation involving long term weight bearing may be considered as aggravated factors in this patient. Pain is the most common complaint, and occurs in about 57% of patients with TDH (1). This is followed by sensory disturbances, motor involvement and even severe complication such as paraplegia (10). The presentation of TDH is nonspecific and there is a relative paucity of examination findings on TDH; therefore diagnosis of this disease is a challenge to emergency doctors. To the best of our knowledge, the complete list initial symptom that have been reported as associated with TDH are chest pain, flank pain, abdominal pain, pelvic pain that may mimic cardiopulmonary, gastrointestinal or genitourinary disorders and psychiatric disease (2-3, 11-15). These facts can lead to a delay in diagnosis, which can result in progressive neurological impairment and even permanent neurological sequelae (10). It has often taken up to six months from the time of first onset to a definitively confirmed diagnosis in many cases of symptomatic TDH (1). In the present case, we pinpointed the disease by the CT scan less than one day after arrival at the ER because of the high alertness of our emergency doctor. Thus, the emergency doctor or the first line general physician needs to play an important role in the diagnosis of this type of ambiguous neurological pattern because prompt recognition and early treatment are the only key point to preventing critical complications. References 1. Arce CA, Dohrmann GJ. Herniated thoracic disks. Neurol Clin 1985;3:383-92. 2. Baranto A, Borjesson M, Danielsson B, Hellstrom M, Sward L. Acute chest pain in a top soccer player due to thoracic disc herniation. Spine (Phila Pa 1976) 2009;34:359-62. 3. Ozturk C, Tezer M, Sirvanci M, Sarier M, Aydogan M, Hamzaoglu A. Far lateral thoracic disc herniation presenting with flank pain. Spine J 2006;6:201-3. 4. Wood KB, Garvey TA, Gundry C, Heithoff KB. Magnetic resonance imaging of the thoracic spine. Evaluation of asymptomatic individuals. J Bone Joint Surg Am 1995;77:1631-8. 5. McInerney J, Ball PA. The pathophysiology of thoracic disc disease. Neurosurg Focus 2000;9:e1. 6. Lyu RK, Chang HS, Tang LM, Chen ST. Thoracic disc herniation mimicking acute lumbar disc disease. Spine (Phila Pa 1976) 1999;24:416-8. 7. Kapetanos GA, Hantzidis PT, Anagnostidis KS, Kirkos JM. Thoracic cord compression caused by disk herniation in Scheuermann s disease: a case report and review of the literature. Eur Spine J 2006;15 Suppl 5:553-8. 8. Overvliet GM, Beuls EA, Ter Laak-Poort M, Cornips EM. Two brothers with a symptomatic thoracic disc herniation at T11-T12: clinical report. Acta Neurochir (Wien) 2009;151:393-6. 9. Deitch K, Chudnofsky C, Young M. T2-3 Thoracic disc herniation with myelopathy. J Emerg Med 2009;36:138-40. 10. Pal B, Johnson A. Paraplegia due to thoracic disc herniation. Postgrad Med J 1997;73:423-5. 11. Whitcomb DC, Martin SP, Schoen RE, Jho HD. Chronic abdominal pain caused by

Thoracic disc herniation 225 thoracic disc herniation. Am J Gastroenterol 1995;90:835-7. 12. Jooma R, Torrens MJ, Veerapen RJ, Griffith HB. Spinal disease presenting as acute abdominal pain: report of two cases. Br Med J (Clin Res Ed) 1983;287:117-8. 13. Rohde RS, Kang JD. Thoracic disc herniation presenting with chronic nausea and abdominal pain. A case report. J Bone Joint Surg Am 2004;86-A:379-81. 14. Xiong Y, Lachmann E, Marini S, Nagler W. Thoracic disk herniation presenting as abdominal and pelvic pain: a case report. Arch Phys Med Rehabil 2001;82:1142-4. 15. Fransen P, Collignon F, Van Den Heule B. Foraminal disc herniation Th9-Th10 mimicking abdominal pain. Acta Orthop Belg 2008;74:881-4.

226 J Emerg Crit Care Med. Vol. 21, No. 4, 2010 1 2 1 3 1 48 99 5 13 99 7 29 1 2 3 40201 110 0937552593 (04)23248108 E-mail: chaohsinwu@hotmail.com