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1 A Vital Step In Screening Male Fertility WEB scsatest.com EML PH TF FX FIND US ON: Facebook A Vital Step In Screening Male Fertility Pinterest Flickr YouTube

2 EVERY BABY HAS A STORY TO TELL LET SCSA DIAGNOSTICS BE PART OF YOUR BABY S STORY SCSA Diagnostics is dedicated to helping trying to conceive (TTC) couples and their doctors find a clear, early answer to infertility problems through the innovative SCSA test. Our test is a discreet, non-invasive and economical alternative that can be done in the privacy of your home. START WITH THE SPERM, END WITH THE ANSWER The SCSA test is the original sperm DNA fragmentation test which has been used by thousands of patients all over the world. Our test results provide answers that can help men make changes that may improve sperm health. Our lab is federally accredited and certified. Only this laboratory can be trusted to provide accurate and timetested results. SCSA Diagnostics = Answers

3 COMMON CAUSES OF DNA FRAGMENTATION DNA FRAGMENTATION CAN BE ATTRIBUTED TO VARIOUS CONDITIONS INCLUDING: INFECTION AGE AIR POLLUTION SMOKING HEAT FEVER DRUG USE PESTICIDES CHEMICALS CANCER & OTHER DISEASES RADIATION X-RAYS Half of couple infertility is due to the male. Sperm DNA damage accounts for much of male factor infertility. Routine semen analysis does not detect sperm DNA damage. HIGH STRESS PRESCRIPTION MEDICINES OBESITY TESTING 1,2,3 Sometimes, reduction or removal of a possible contributor can reduce the elevated DNA fragmentation levels. The SCSA test measures broken DNA and abnormal proteins attached to DNA. Both of these factors are known to cause miscarriages and pregnancy failures.

4 The answers to infertility aren t always obvious. Most infertile men will not have any symptoms. Even when the classic semen analysis of sperm count, motility and morphology are in normal range, the sperm may still have broken DNA that cannot sustain normal embryo growth Male factor infertility, in most men, will continue unless treated. A step in the right direction toward treatment, is to obtain the correct diagnosis. A SCSA test can be a big part of the correct diagnosis. Who Should Have A Sperm DNA Fragmentation Screening? All couples with unexplained infertility for more than 6 months to a year Couples with a history of spontaneous miscarriages Couples considering IUI, IVF, ICSI Men over 40 years of age Men who are smokers Men on certain prescription medicines Men who have been treated for cancer Men exposed to toxic agents Men considering varicocele repair Men under high stress If you are seeking quality and assurance of excellence, with cutting edge technology and unsurpassed clinical results, SCSA Diagnostics is the lab you ll want to choose. SCSA A STEP IN THE RIGHT DIRECTION

5 Babies are such a nice way to start people. Don Herrold The American Pregnancy Association states that male factor infertility is related to approximately 50% of all couple infertility cases. By measuring a sperm sample, SCSA Diagnostics can quickly identify the presence of damaged, immature and unhealthy sperm, a common cause behind unsuccessful pregnancies. Male infertility is not unusual. About one in three men diagnosed with unexplained infertility have an abnormally high breakage of sperm DNA the all-important half of an embryo s genetic makeup. Early testing can spare their partners a great deal of unnecessary discomfort and expense. Talk to your doctor today about having a SCSA test.

6 A visit to your fertility specialist should start the evaluation for male infertility. The specialist will likely begin with a basic interview and exam that includes: WE CAN PARTNER WITH YOUR DOCTOR A full medical and reproductive history, along with any surgeries you ve had and any medication you re taking. Ordering a test is easy! To place an order, you can go online to our website and click on order now. It s quick, easy and convenient. A semen collection kit can be sent either to the patient s home or the doctor s office. Collection supplies, directions and shipping instructions are included in each kit. Once the sample is shipped, the results will be available within one week. That s all there is to it. A physical exam. Lifestyle questions including your exercise, smoking and drug use. A frank discussion about your sexual life, including pregnancy successes or failures. PLACE AN ORDER From there, your physician may order diagnostic tests to identify where the problems lie. SCSA Diagnostics is the lab that many physicians choose to perform one of those tests: a sperm DNA fragmentation test.