Bispecific Antibody Therapeutics Market (2nd Edition),

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1 Brochure More information from Bispecific Antibody Therapeutics Market (2nd Edition), Description: The concept of bispecific antibodies is increasingly gaining traction in the pharma industry owing to several therapeutic advantages and their potential to address challenges known with the monoclonal antibody based therapies. Bispecific antibodies are artificial antibodies created by joining together two monoclonal antibodies (or parts) that target different epitopes. The resulting antibody has binding affinities for two or three different epitopes concurrently. The market is still in its infancy. With the EMA approval for Removab in 2009 and recent filing for blinatumomab, a great deal of interest has been generated in the bispecific antibody market. The pipeline, which is rich and diverse, has drugs being developed for both oncological and non-oncological indications. These drugs are based on about 50 different technological platforms developed by companies such as Trion Pharma, Amgen, AbbVie, Ablynx, Affimed and MacroGenics amongst others. The platforms are based on the concepts of chemical crosslinking, hybrid hybridomas, with the latest being recombinant techniques. Different binding sites can be exploited to produce bispecific systems with different mechanisms, such as the T cell engager system. During the course of our research, we came across 37 molecules currently in different stages of clinical development. Over 75% of these molecules are industry sponsored and we expect around 8-9 of them to be launched by the end of this decade, providing the much needed push to this market. In addition to the clinical pipeline, we have identified over 70 molecules which are currently in preclinical / discovery phase. Technological advancements, especially in the purification of bispecific antibodies will ensure the development of products with improved safety, potency and efficacy profile. As more products move from pipeline to the market, we expect to see an increase in the investment in this area from various quarters. The 2nd edition of the Bispecific Antibody Therapeutics Market, report extensively studies the current and upcoming market of the bispecific antibodies for therapeutic use. This new class of antibody based therapeutics are likely to help target and combat multifactorial diseases through their potential to bind two antigens simultaneously. The report covers bispecific antibody drugs currently available in the market as well as in various stages of clinical trials. These drugs are being developed for both oncological as well as non-oncological indications. The report highlights various companies which are active in the market and discusses, in detail, the underlying technologies which form the basis of many of the pipeline drugs. Expecting more FDA and EMA approvals of bispecific antibodies in the coming years, one of the key objectives of this report has been to forecast the bispecific antibody market, currently at a nascent stage, over the course of next ten years. This is done by analysing - Molecules in pipeline and drugs approved for marketing across various geographical regions - Research programs, focused on bispecific antibody therapeutics, of global pharmaceutical companies and recently established start-ups - Technologies to produce bispecific antibodies - Development and sales potential based on target consumer segments, expected pricing and the likely adoption rate of the new drugs, some of which are expected to be used for lifecycle management of existing drugs - Competitive landscape and inherent threats to growth in the short term and long term The report provides short-mid term and long term market forecasts for the period and , respectively. We have discussed, in detail, the key drivers behind the growth of this market. The research, analysis and insights presented in this report include the sales of 11 marketed and pipeline bispecific antibodies. Owing to the niche nature of this market, with most products in the pipeline, we have provided three scenarios for our market forecast to add robustness to our model. The conservative, base and optimistic scenarios represent three different tracks of market evolution. The figures mentioned in this report are in USD, unless otherwise specified.

2 Contents: 1. PREFACE 1.1. Scope of the Report 1.2. Research Methodology 1.3. Chapter Outlines 2. EXECUTIVE SUMMARY 3. INTRODUCTION 3.1. Chapter Overview 3.2. Immunotherapy: Antibody Ammunitions 3.3. Antibody Based Therapeutics Twelve of the Approved Antibody Based Therapeutics are Non-Canonical Dominance of Antibody Based Therapeutics 3.4. Structure of an Antibody 3.5. Monoclonal Antibodies v/s. Bispecific Antibodies 3.6. Bispecific Antibody Formats 3.7. Evolution of Bispecific Antibodies First Generation Bispecific Antibodies Triomabs: Made Using Hybridomas/ Quadromas Shortcoming of First Generation Bispecific Antibodies Second Generation Bispecific Antibodies Tandem Single-chain Variable Fragment (scfv) Diabodies Two-in-one antibody Dual Variable Domain Antibodies (DVD-Ig) Shortcoming of Recombinant Bispecific Antibodies 3.8. Types of Bispecific Antibodies by Mode of Action T Cell Engagement Pre-targeting Systems Ligand Neutralisation and Cross Linking of Receptors System 3.9. Companies Active in the Market 4. MARKET OVERVIEW AND PIPELINE OF BISPECIFIC ANTIBODIES 4.1. Introduction 4.2. Drugs Indicated for Oncological Diseases 4.3. Drugs Indicated For Non-Oncological Diseases 4.4. Drugs in Preclinical Trials 4.5. Pipeline Analysis Drugs are Well Distributed in Phase I and Phase II of Clinical Trials Mechanism Using CD3 Antigen Recognition Pipeline Dominated by Drugs Indicated for Oncological Diseases Companies with the Most Active Pipeline 5. CURRENT MARKET AND FORECAST 5.1. Introduction Scope and Limitations Assumptions for Market Forecast 5.2. Overall Bispecific Antibodies Market Overall Bispecific Antibodies Market Forecast: Short-Midterm, Overall Bispecific Antibodies Market Forecast: Long Term, Evolution of the Bispecific Antibody Market: 2014, 2019 and Catumaxomab / Removab (Neovii Biotech) Drug Specifications Structure and Mechanism of Action Orphan Drug Designations Geographical Presence Cost Manufacturing Current Status of Development Historical Sales ( Q1 2013) Reimbursement Market Opportunity in Cancer Associated Malignant Ascites Catumaxomab / RemovabSales Forecast: Short-Mid Term,

3 Catumaxomab / RemovabSales Forecast: Long Term, Blinatumomab / MT 103/ MEDI 538 / AMG 103 (Amgen / Astellas Pharma) Drug Specifications Mechanism of Action Amgen Driving Further Development Orphan Drug Designation Current Development Status Key Clinical Trial Results Competitive Landscape Blinatumomab / MT 103/ MEDI 538 / AMG 103 Sales Forecast: Short-Mid Term, Blinatumomab / MT 103/ MEDI 538 / AMG 103 Sales Forecast: Long Term, SAR (Sanofi) Drug Specifications Mechanism of Action Orphan Drug Status Idiopathic Pulmonary Fibrosis: An Attractive Opportunity Current Status of Development SAR Sales Forecast: Short-Mid Term, SAR Sales Forecast: Long Term, MM-111 (Merrimack Pharmaceuticals) Drug Specifications Mechanism of Action Orphan Drug Designation Manufacturing Current Development Status Key Clinical Trial Results Companion Diagnostic Under Development MM-111 Sales Forecast: Short-Mid Term, MM-111 Sales Forecast: Long Term, ACE910 / RG6013 (Chugai, Roche) Drug Specifications Mechanism of Action Current Development Status Competiton for ACE ACE910 / RG6013 Sales Forecast: Short-Mid Term, ACE910 / RG6013 Sales Forecast: Long Term, Duligotumab / MEHD7945A / RG7597 (Roche / Genentech) Drug Specifications Structure and Mechanism of Action Current Status of Development Key Clinical Trial Results Competition for Duligotumab Duligotumab/MEHD7945A / RG7597Sales Forecast: Long Term, ABT-981 (AbbVie) Drug Specifications Mechanism of Action Current Development Status Key Clinical Trial Results Competiton for ABT ABT-981 Sales Forecast: Long Term, ABT-122 (AbbVie) Drug Specifications Mechanism of Action Current Development Status Competition for ABT ABT-122 Sales Forecast: Long Term, RG7221/ RO (Roche) Drug Specifications Mechanism of Action Current Development Status Competition for RG RG7221 / RO Sales Forecast: Long Term, ALX-0061 (Ablynx)

4 Drug Specifications Mechanism of Action Desirable Features of ALX Current Status of Development Key Clinical Trial Results Competiton for ALX Collaboration with AbbVie ALX-0061 Sales Forecast: Long Term, Ozoralizumab / ATN-103 (Ablynx) Drug Specifications Mechanism of Action Highs and Lows of Development CurrentStatus of Development Key Clinical Trial Results Competition for Ozoralizumab Ozoralizumab / ATN-103 Sales Forecast: Long Term, Profiles of Some Other Pipeline Drugs AFM 13 (Affimed) Phase II Planned Drug Specifications Mechanism of Action Co-funding Agreement with the Leukemia and Lymphoma Society Current Development Status and Future Plans Competiton for AFM CD20Bi / FBT-A05 / Lymphomun (Fresenius Biotech) investigator-sponsored trials Drug Specifications and Mechanism of Action Current Development Status TF2 (Immunomedics) pretargeting imaging and radioimmunotherapy agent Drug Specifications Mechanism of Action Current Development Status Ertumaxomab/Rexomun (Fresenius Biotech) investigator-sponsored trials Drug Specifications Current Development Status 6. TECHNOLOGY PLATFORMS 6.1. Introduction 6.2. Bispecific Antibody Production: Technology Providers and Available Technologies 6.3. Promising Technologies Triomab / Quadroma (Trion Pharma) The Technology Drugs Based on Triomab Pharmaceutical Companies Showing Interest in the Technology Tribody Technology (Biotecnol) The Technology Drugs Based on Tribody Pharmaceutical Companies Showing Interest in the Technology Advantages of Tribody Technology Bispecific T Cell Engager / BiTE (Amgen) The Technology Drugs Based on BiTE Pharmaceutical Companies Showing Interest in the Technology Advantages of BiTE Technology DART (MacroGenics) The Technology Drugs Based on DART Pharmaceutical Companies Showing Interest in the Technology Advantages of DART DuoBody (Genmab) The Technology Drugs Based on DuoBody Pharmaceutical Companies Showing Interest in the Technology Advantages of DuoBody Technology TandAb (Affimed)

5 The Technology Drugs Based on TandAb Advantages of TandAb Technology DVD-Ig (AbbVie) The Technology Drugs Based on DVD-Ig Advantages of DVD-Ig Technology Nanobody (Ablynx) The Technology Drugs Based on Nanobody Pharmaceutical Companies Showing Interest in the Technology Advantages of Nanobody CrossMab Technology (Roche) The Technology Drugs Based on CrossMab Advantages of CrossMab Dock and Lock (Immunomedics) The Technology Drugs Based on DNL Advantages of DNL Technology 7. PARTNERSHIPS: BACKBONE OF THE GROWING BISPECIFIC INDUSTRY 7.1. Chapter Overview 7.2. Recent Partnerships Partnership Models Collaborations Amongst Stakeholders are on a Rise Product Development Model is the Preferred Mode of Collaboration Most Active Companies 8. PROFILES OF LEADING COMPANIES 8.1. Chapter Overview 8.2. AbbVie Overview Financial Performance Technology and PipelineDrugs DVD-Ig: The Proprietary Technology Pipeline Drugs Other Information 8.3. Ablynx Overview Financial Performance Funding Technology and Pipeline Drugs Nanobody: The Proprietary Technology Pipeline Drugs Other Information 8.4. Affimed Overview Funding Technology and Pipeline Drugs TandAb Technology Pipeline Drugs Other Information 8.5. Amgen Overview Financial Performance Technology and Pipeline Drugs BiTE: The Proprietary Technology Pipeline Drugs Other Information 8.6. Immunomedics Overview Financial Performance

6 Technology and Pipeline Drugs DOCK-AND-LOCK (DNL): The Proprietary Technology Pipeline Drugs 8.7. Merrimack Pharmaceuticals Overview Financial Performance Technology and Pipeline Drugs Other Information 8.8. Merus Overview Funding Technology and Pipeline Drugs Biclonics: The Proprietary Technology Pipeline Drugs Other Information 8.9. Neovii Biotech Overview Financial Performance Technologyand Pipeline Drugs Removab: The only Marketed Bispecific Antibody Other Information Roche Overview Financial Performance Technology and Pipeline Drugs The Proprietary Technologies Pipeline Drugs Other Information Sanofi Overview Financial Performance Technology and Pipeline Drugs TBTI (tetravalent bispecific tandem Ig): The Proprietary Technology Pipeline Drugs Brief Company Profiles Baliopharm Bayer Biotecnol GSK MacroGenics NovImmune Numab Paktis Antibody Services GmbH PharmAbcine Sorrento Therapeutics Synimmune Xencor Zyngenia 9. SWOT ANALYSIS 9.1. Overview 9.2. Strengths 9.3. Weaknesses 9.4. Opportunities 9.5. Threats 10. INTERVIEW TRANSCRIPTS 11. CONCLUSIONS A Budding Market Ready to Bloom With Several Advantages, Bispecific Antibodies are likely to Step Shead of Competition Improvements in Purification Systems of Bispecific Antibodies is Critical Concluding Remarks

7 12. APPENDIX 1: LIST OF COMPANIES AND ORGANISATIONS 13. APPENDIX 2: TABULATED DATA List of Tables: Table 3.1 Approved Antibody Based Therapeutics Table 4.1 List of Bispecific Antibodies: Clinical Trials (Oncology) Table 4.2 List of Bispecific Antibodies: Clinical Trials (Non-Oncology) Table 4.3 List of Bispecific Antibodies: Preclinical / Discovery Table 5.1 Bispecific Antibodies in Clinical Development (Phase II and Higher): Current Development Phase and Expected Launch Year Table 5.2 Removab: Orphan Drug Designations Table 5.3 Removab: Treatment Schedule and Cost Table 5.4 Removab: Ongoing Clinical Trials Table 5.5 Blinatumomab: Orphan Drug Designations Table 5.6 Blinatumomab / MT 103/ MEDI 538 / AMG 103: Ongoing Clinical Trials Table 5.7 Comparison of the Marketed Targeted Inhibitors for ALL Table 5.8 Comparison of Blinatumomab / MT 103/ MEDI 538 / AMG 103 and SAR3419 Table 5.9 Drugs under Development for Idiopathic Pulmonary Fibrosis, 2014 Table 5.10 SAR156597: Ongoing Clinical Trials Table 5.11 MM-111: Ongoing Clinical Trials Table 5.12 ACE910: Ongoing Clinical Trials Table 5.13 Duligotumab / MEHD7945A / RG7597: Ongoing Clinical Trials Table 5.14 Duligotumab / MEHD7945A / RG7597: Competitor Drug Analysis Table 5.15 ABT-981: Ongoing Clinical Trials Table 5.16 ABT-122: Ongoing Clinical Trials Table 5.17 RG7221: Ongoing Clinical Trials Table 5.18 ALX-0061: Ongoing Clinical Trials Table 5.19 ALX-0061: Competitor Drug Analysis Table 5.20 Ozoralizumab / ATN-103: Ongoing Clinical Trials Table 5.21 Comparison of Leading Anti-Rheumatic Drugs Table 5.22 AFM13: Ongoing Clinical Trials Table 5.23 Comparison of Adcetris with AFM 13 Table 5.24 CD20Bi: Ongoing Clinical Trials Table 5.25 TF2: Ongoing Clinical Trials Table 5.26 Rexomun: Ongoing Clinical Trials Table 6.1 Bispecific Antibodies: List of Technology Platforms Table 6.2 Drugs Based on Triomab Technology Table 6.3 Drugs Based on Tribody Technology Table 6.4 Drugs Based on BiTE Technology Table 6.5 Drugs Based on DART Table 6.6 Drugs Based on TandAb Technology Table 6.7 Drugs Based on DVD-Ig Technology Table 6.8 Drugs Based on Nanobody Technology Table 6.9 Drugs Based on CrossMab Technology Table 6.10 Drugs Based on Dock and Lock Technology Table 7.1 List of Partnerships, Table 8.1 AbbVie: Pipeline of Bispecific Antibodies Table 8.2 Ablynx: Pipeline of Bispecific Antibodies Table 8.3 Affimed: Pipeline of Bispecific Antibodies Table 8.4 Amgen: Pipeline of Bispecific Antibodies Table 8.5 Immunomedics: Pipeline of Bispecific Antibodies Table 8.6 Merrimack Pharmaceuticals: Pipeline of Bispecific Antibodies Table 8.7 Merus: Pipeline of Bispecific Antibodies Table 8.8 Neovii Biotech: Pipeline of Bispecific Antibodies Table 8.9 Roche: Pipeline of Bispecific Antibodies Table 8.10 Sanofi: Pipeline of Bispecific Antibodies Table 8.11 Baliopharm: Pipeline of Bispecific Antibodies Table 8.12 Bayer: Pipeline of Bispecific Antibodies Table 8.13 Biotecnol: Pipeline of Bispecific Antibodies Table 8.14 GSK: Pipeline of Bispecific Antibodies Table 8.15 MacroGenics: Pipeline of Bispecific Antibodies

8 Table 8.16 NovImmune: Pipeline of Bispecific Antibodies Table 8.17 Numab: Pipeline of Bispecific Antibodies Table 8.18 PharmAbcine: Pipeline of Bispecific Antibodies Table 8.19 Sorrento Therapeutics: Pipeline of Bispecific Antibodies Table 8.20 Synimmune: Pipeline of Bispecific Antibodies Table 8.21 Xencor: Pipeline of Bispecific Antibodies Table 8.22 Zyngenia: Pipeline of Bispecific Antibodies Table 9.1 SWOT Analysis Table 9.2 Contract Manufacturing Organisations with Bispecific Antibody Capabilities Screening, Expression or Purification Table 9.3 Companies Working to Develop IgG/Non-IgG Fusion Therapeutics Table 13.1 Approved Non-Canonical Antibody Based Therapeutics Table 13.2 Sales (USD BN) of Top 10 drugs, 2013 Table 13.3 Industry Sponsored Pipeline Drugs: By Phase of Development Table 13.4 Industry Sponsored Pipeline Drugs: By Type of Bispecific System Table 13.5 Industry Sponsored Pipeline Drugs: By Indication Table 13.6 Industry Sponsored Oncology Bispecific Drugs: By Type of Cancer Table 13.7 Overall Bispecific Antibodies Market (USD MM), Short-Midterm Forecast: (Base Table 13.8 Overall Bispecific Antibodies Market (USD MM), Short-Midterm Forecast: (Conservative Table 13.9 Overall Bispecific Antibodies Market (USD MM), Short-Midterm Forecast: (Optimistic Table Overall Bispecific Antibodies Market (USD MM), Long Term Forecast: (Base Table Overall Bispecific Antibodies Market (USD MM), Long Term Forecast: (Conservative Table Overall Bispecific Antibodies Market (USD MM), Long Term Forecast: (Optimistic Table Catumaxomab/Removab Market (USD MM), Short-Mid Term Forecast: (Base Table Catumaxomab/Removab Market (USD MM), Short-Mid Term Forecast: (Conservative Table Catumaxomab/Removab Market (USD MM), Short-Mid Term Forecast: (Optimistic Table Catumaxomab/Removab Market (USD MM), Long Term Forecast: (Base Table Catumaxomab/Removab Market (USD MM), Long Term Forecast: (Conservative Table Catumaxomab/Removab Market (USD MM), Long Term Forecast: (Optimistic Table Blinatumomab / MT 103/ MEDI 538 / AMG 103 Market (USD MM), Short-Mid Term Forecast: (Base Table Blinatumomab / MT 103/ MEDI 538 / AMG 103 Market (USD MM), Short-Mid Term Forecast: (Conservative Table Blinatumomab / MT 103/ MEDI 538 / AMG 103 Market (USD MM), Short-Mid Term Forecast: (Optimistic Table Blinatumomab / MT 103/ MEDI 538 / AMG 103 Market (USD MM), Long Term Forecast: (Base Table Blinatumomab / MT 103/ MEDI 538 / AMG 103 Market (USD MM), Long Term Forecast: (Conservative Table Blinatumomab / MT 103/ MEDI 538 / AMG 103 Market (USD MM), Long Term Forecast: (Optimistic Table SAR Market (USD MM), Short-Mid Term Forecast: (Base Table SAR Market (USD MM), Short-Mid Term Forecast: (Conservative Table SAR Market (USD MM), Short-Mid Term Forecast: (Optimistic Table SAR Market (USD MM), Long Term Forecast: (Base Table SAR Market (USD MM), Long Term Forecast: (Conservative Table SAR Market (USD MM), Long Term Forecast: (Optimistic Table MM-111 Market (USD MM), Short-Mid Term Forecast: (Base Table MM-111 Market (USD MM), Short-Mid Term Forecast: (Conservative Table MM-111 Market (USD MM), Short-Mid Term Forecast: (Optimistic Table MM-111 Market (USD MM), Long Term Forecast: (Base Table MM-111 Market (USD MM), Long Term Forecast: (Conservative Table MM-111 Market (USD MM), Long Term Forecast: (Optimistic

9 Table ACE910 / RG6013 Market (USD MM), Short-Mid Term Forecast: (Base Table ACE910 / RG6013 Market (USD MM), Short-Mid Term Forecast: (Conservative Table ACE910 / RG6013 Market (USD MM), Short-Mid Term Forecast: (Optimistic Table ACE910 / RG6013 Market (USD MM), Long Term Forecast: (Base Table ACE910 / RG6013 Market (USD MM), Long Term Forecast: (Conservative Table ACE910 / RG6013 Market (USD MM), Long Term Forecast: (Optimistic Table Duligotumab / MEHD7945A / RG7597 Market (USD MM), Long Term Forecast: (Base Table Duligotumab / MEHD7945A / RG7597 Market (USD MM), Long Term Forecast: (Conservative Table Duligotumab / MEHD7945A / RG7597 Market (USD MM), Long Term Forecast: (Optimistic Table ABT-981 Market (USD MM), Long Term Forecast: (Base Table ABT-981 Market (USD MM), Long Term Forecast: (Conservative Table ABT-981 Market (USD MM), Long Term Forecast: (Optimistic Table ABT-122 Market (USD MM), Long Term Forecast: (Base Table ABT-122 Market (USD MM), Long Term Forecast: (Conservative Table ABT-122 Market (USD MM), Long Term Forecast: (Optimistic Table RG7221 / RO Market (USD MM), Long Term Forecast: (Base Table RG7221 / RO Market (USD MM), Long Term Forecast: (Conservative Table RG7221 / RO Market (USD MM), Long Term Forecast: (Optimistic Table ALX-0061 Market (USD MM), Long Term Forecast: (Base Table ALX-0061 Market (USD MM), Long Term Forecast: (Conservative Table ALX-0061 Market (USD MM), Long Term Forecast: (Optimistic Table Ozoralizumab / ATN-103 Market (USD MM), Long Term Forecast: (Base Table Ozoralizumab / ATN-103 Market (USD MM), Long Term Forecast: (Conservative Table Ozoralizumab / ATN-103 Market (USD MM), Long Term Forecast: (Optimistic Table AbbVie: Financial Performance, 2012-Q (USD BN) Table Amgen: Financial Performance, 2012-Q (USD BN) Table Immunomedics: Financial Performance, (USD MM) Table Merrimack: Financial Performance, Q (USD MM) Table Roche: Financial Performance, 2012-Q (CHF BN) Table Sanofi: Financial Performance, 2012-Q (EUR BN) List of Figures: Figure 2.1 Bispecific Antibody Therapeutics: Market Map Figure 3.1 Number of Approved Non-Canonical Antibody Based Therapeutics Figure 3.2 Sales of Top 10 Drugs (USD BN), 2013 Figure 3.3 Parts of an Antibody Figure 4.1 Pipeline Drugs: By Phase of Development Figure 4.2 Pipeline Drugs: By Type of Bispecific System Figure 4.3 Pipeline Drugs: By Indication Figure 4.4 Oncology Bispecific Drugs: By Types of Cancer Figure 5.1 Overall Bispecific Antibodies Market (USD MM), Short-Midterm Forecast: (Base Figure 5.2 Overall Bispecific Antibodies Market (USD MM), Long Term Forecast: (Base Figure 5.3 Evolution of Bispecific Antibodies Market: 2014, 2019 and 2024 (Base Figure 5.4 Removab Quarterly Sales, (EUR MM) Figure 5.5 Malignant Ascites Market Share (%): Distribution by Type of Cancer Figure 5.6 Catumaxomab / Removab Market (USD MM), Short-Mid Term Forecast: (Base Figure 5.7 Catumaxomab / Removab Market (USD MM), Long Term Forecast: (Base Figure 5.8 Blinatumomab / MT 103 / MEDI 538 / AMG 103 Market (USD MM), Short-Mid Term Forecast: (Base Figure 5.9 Blinatumomab / MT 103 / MEDI 538 / AMG 103 Market (USD MM), Long Term Forecast: (Base Figure 5.10 SAR Market (USD MM), Short-Mid Term Forecast: (Base Figure 5.11 SAR Market (USD MM), Long Term Forecast: (Base Figure 5.12 MM-111 Market (USD MM), Short-Mid Term Forecast: (Base

10 Figure 5.13 MM-111 Market (USD MM), Long Term Forecast: (Base Figure 5.14 ACE910/ RG6013 Market (USD MM), Short-MId Term Forecast: (Base Figure 5.15 ACE910/ RG6013 Market (USD MM), Long Term Forecast: (Base Figure 5.16 Duligotumab / MEHD7945A / RG7597 Market (USD MM), Long Term Forecast: (Base Figure 5.17 ABT-981 Market (USD MM), Long Term Forecast: (Base Figure 5.18 ABT-122 Market (USD MM), Long Term Forecast: (Base Figure 5.19 RG7221/ RO Market (USD MM), Long Term Forecast: (Base Figure 5.20 ALX-0061 Market (USD MM), Long Term Forecast: (Base Figure 5.21 Sales of Leading Anti-rheumatics Drugs, 2013(USD BN) Figure 5.22 Ozoralizumab / ATN-103 Market (USD MM), Long Term Forecast: (Base Figure 7.1 Bispecific Antibody Partnerships by Year, Pre Figure 7.2 Bispecific Antibody Partnerships: Distribution by Type of Partnership Figure 7.3 Bispecific Antibodies Partnerships: Major Stakeholders Figure 8.1 AbbVie: Financial Performance, 2012 Q (USD BN) Figure 8.2 Amgen: Financial Performance, 2012 Q (USD BN) Figure 8.3 Immunomedics: Financial Performance, (USD MM) Figure 8.4 Merrimack: Financial Performance, Q (USD MM) Figure 8.5 Roche: Financial Performance, 2012 Q (CHF BN) Figure 8.6 Sanofi: Financial Performance, 2012 Q (EUR BN) Figure 11.1 Bispecific Antibodies Market Forecast (USD MM): 2014, 2019, 2024 Ordering: Order Online - Order by Fax - using the form below Order by Post - print the order form below and send to Research and Markets, Guinness Centre, Taylors Lane, Dublin 8, Ireland.

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