Ministero della Salute Direzione Generale Ricerca Scientifica e Tecnologica

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1 Ministero della Salute Direzione Generale Ricerca Scientifica e Tecnologica BANDO 2009 RICERCA FINALIZZATA e GIOVANI RICERCATORI Graduatoria 1 RF Development of Alzheimer disease therapeutics based on a natural variant of amyloid beta that hinders amyloidogenesis 5 biomedica Brain Disorders and ,00 2 RF Micro RNA Regulated Gene Transfer for Treatment of Autoimmune Diseases 5 biomedica Immunology 3 RF BLOOD PRESSURE CONTROL AND CARDIOVASCULAR RISK MANAGEMENT IN HIGH RISK HYPERTENSIVE PATIENTS. CLINICAL EFFICACY AND FEASIBILITY OF HOME TELEMONITORING. 5,5 clinico assistenziale Healthcare Delivery and Methodologies ,00 4 RF Development of osteoinductive micro and nano structured polymer surfaces for bone replacement 5,5 biomedica Bioengineering Sciences and Technologies ,00 5 RF Cognitive, imaging and genetic predictors of behavioral disturbances in Parkinson s disease 5,75 clinico assistenziale Brain Disorders and ,00 6 RF Role of alpha6 nicotinic receptor subunit in tobacco dependence 6 biomedica Brain Disorders and ,00 7 RF Role of autophagy in neuromuscular diseases 6 biomedica Cell Biology ,00 8 GR Allergic components in experimental multiple sclerosis: novel targets for immune intervention 6 biomedica Immunology ,00 9 RF ITALIAN MULTICENTRE RANDOMIZED CLINICAL TRIAL ON SUBLICNICAL ACUTE REJECTION IN KNEY TRASNPLANT RECIPIENTS 6 clinico assistenziale Immunology ,00 10 RF Analysis and manipulation of LXR signaling to induce successful antitumor responses 6 biomedica Immunology ,00 Pagina 1 di 244

2 11 RF Epigenetic control of breast cancer progression: animal and clinical studies 6 biomedica Biobehavioral and Behavioral Processes ,00 12 RF Induced pluripotent stem cells (ipsc) in the treatment of TCIRG1 dependent osteopetrosis: a step by step reproduction of the entire therapeutic process in the mouse 6 biomedica Genes, Genomes and ,00 13 GR Self Extinction of Stem Cells and the Spontaneous Regression/Dormancy of Breast Cancer 6,17 biomedica Oncology 1 Basic ,00 14 RF Role of delta16her2 splice variant in tumor progression and in response to biodrugs targeting HER2 receptor 6,25 biomedica Oncology 1 Basic ,00 15 GR Positron Emission Tomography (PET)/Computerized Tomography (CT) and Magnetic Resonance Imaging (MRI) fusion for the in vivo characterization of atherosclerotic plaques at risk 6,3 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering 16 RF INTERACTION FRAMEWORK BETWEEN PATIENT ADVOCACY GROUPS AND CANCER CENTERS ON SARCOMAS, AS A MODEL FOR RARE CANCERS 6,5 clinico assistenziale Healthcare Delivery and Methodologies ,00 17 RF SILS Study (Single Incision Laparoscopic Surgery Study) 6,5 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering ,00 18 RF Uncovering the genetic footprint of T cells residing in the pancreatic draining lymph nodes of patients with type 1 diabetes 6,5 biomedica Immunology ,00 19 GR ENVIROMENTAL, GENETIC AND EPIGENETIC COMPONENTS IN DRUG ABUSE AND RELAPSE TO DRUG SEEKING 6,5 biomedica Brain Disorders and 20 RF SNAP25 heterozygous mice as models to identify a safer pharmacological treatment for ADHD 6,5 biomedica Brain Disorders and ,00 21 RF Treatment optimization of HER2 positive breast cancer 6,5 clinico assistenziale Oncology 2 Clinical ,00 22 RF Investigation of the specific role for mglu2 and mglu3 metabotropic glutamate receptors in chronic pain. 6,5 biomedica Integrative, Functional, and Cognitive Neuroscience ,00 Pagina 2 di 244

3 23 RF Study of coagulation and tumor associated neutrophils in intestinal cancer development. 6,75 biomedica Immunology ,00 24 GR Definition of magnetic resonance imaging (MRI) biomarkers of cognitive impairment in multiple sclerosis patients with different disease phenotypes, from childhood to adulthood: application and integration of structural and functional MR based techniques 6,75 clinico assistenziale Brain Disorders and 25 GR Novel approaches to imaging and treatment of epilepsy: virus like striped nanoparticles. 7 biomedica Bioengineering Sciences and Technologies ,00 26 RF Analysis of the inkt cell DCs crosstalk for tolerance induction and prevention of autoimmune Type 1 Diabetes 7 biomedica Immunology , GR Ruvbl 1 in the pathogenesis of Hepatocellular Carcinoma. 7 biomedica Oncology 1 Basic RF Parameter invariant TCP NTCP Radiotherapy Plan Ranking 7 biomedica Oncology 2 Clinical GR Potential involvement of the atypical amino acid D aspartate in schizophrenia 7 biomedica Brain Disorders and RF HMGB1 blockade as a therapeutic tool in Systemic Lupus Erythematosus 7 biomedica Musculoskeletal, Oral and Skin Sciences , , , ,00 31 RF NEXT GENERATION DNA SEQUENCING IN DEEP VEIN THROMBOSIS 7 biomedica Vascular and Hematology ,00 32 RF Development of innovative methods for the detection of pathogenic bacteria in fresh vegetables and in irrigation and washing water of crops 7 biomedica Veterinary Food Safety FOSA 33 RF Toll like receptors at the intersection between infection and seizures: role in epileptogenesis and in developmental epilepsy 7 biomedica Brain Disorders and ,00 34 GR Exploring Opa1 dependent mitochondrial cristae remodelling as a therapeutic target in cancer 7 biomedica Cell Biology Pagina 3 di 244

4 35 GR Modelling and treatment of cystic fibrosis through an integrated Systems Biology approach 7 biomedica Cardiovascular and ,00 36 GR In pursuit of novel neuroprotective strategies for Parkinson s disease: understanding the role of PINK1 in regulating autophagy and apoptosis 7 biomedica Molecular, Cellular, and Developmental Neuroscience ,00 37 GR GENETIC VARIANTS AND SUSCEPTIBILITY TO SEVERE AND/OR RECURRENT LOWER RESPIRATORY TRACT INFECTIONS WITH WHEEZING IN CHILDREN 7 clinico assistenziale Infectious Diseases and Microbiology 38 RF Role of p53/p63/p73 family in breast cancer stem cells 7 biomedica Oncology 1 Basic ,00 39 RF Mechanisms of de regulation of self renewal and differentiation in cancer stem cells 7 biomedica Oncology 1 Basic 40 RF The novel emergence of atypical animal and human TSEs. A clinical, pathological, molecular, and experimental approach to define interspecies similarities and strain connections 7 biomedica Veterinary Animal Health ANHE 41 RF Mechanism of action and in vivo efficacy of old and new glucocorticoids and new combination treatments for an improved outcome of spinal cord injury 7,25 biomedica Brain Disorders and 42 GR Development of innovative preclinical mouse models to define the molecular mechanisms of trasformation of Anaplastic Large T cell Lymphoma 7,25 biomedica Oncology 2 Clinical ,00 43 GR Study of Radiobiological and Radiotherapic Effects of a Novel Laser Driven Electron Accelerator 7,25 biomedica Oncology 2 Clinical 44 RF Health technology assessment of needlestick prevention devices to enhance safety of health care workers 7,25 clinico assistenziale Healthcare Delivery and Methodologies , RF The zoonotic potential of Transmisible Spongiform Encephalopathies 7,25 biomedica Brain Disorders and RF Targeting HMGB1 in inflammation associated tumors 7,34 biomedica Oncology 1 Basic , ,00 Pagina 4 di 244

5 47 GR Novel nanostructured coating for dental implants and prostheses with high osseointegration efficiency 7,5 biomedica Musculoskeletal, Oral and Skin Sciences ,00 48 RF Molecular bases and pathogenic mechanisms of hereditary spinocerebellar degenerations caused by defects of mitochondrial protein quality control 7,5 biomedica Brain Disorders and ,00 49 GR Design, development and pilot clinical application of innovative biofeedback systems for multidisciplinary motor rehabilitation in Parkinson s Disease 7,5 biomedica Musculoskeletal, Oral and Skin Sciences ,00 50 RF Allotransplantation of mesoangioblasts for Duchenne Muscular Dystrophy: a phase I/II clinical trial. 7,5 clinico assistenziale Musculoskeletal, Oral and Skin Sciences ,00 51 GR Investigation of novel predictors of response to antiangiogenic treatments in hepatocellular carcinoma: Contrast Enhanced Ultrasonography (CEUS), VEGFR2 targeted CEUS and elastosonography 7,5 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering ,00 52 GR Effect on professional practice and health care outcomes of computerized evidence based information system and clinical decision support: a randomized controlled trial in orthopedics 7,5 clinico assistenziale Healthcare Delivery and Methodologies ,00 53 RF Metabolic defects in stem cells as major causes of age related diseases 7,5 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences ,00 54 GR Functional and genetic dissection of Pseudomonas aeruginosa and host response to respiratory infection 7,5 biomedica Infectious Diseases and Microbiology ,00 55 GR Promote self other merging in Autism Spectrum Conditions by combined behavioural manipulation and Noninvasive Brain Stimulation. 7,5 clinico assistenziale Brain Disorders and ,00 56 RF A multicenter randomised trial of contrast enhanced MR imaging as a breast cancer screening tool in addition to mammography and ultrasonography in women at intermediate risk. Feasibility, and short term results. 7,5 biomedica Healthcare Delivery and Methodologies ,00 57 RF Metabotropic glutamate receptors: new targets for the treatment of autoimmune disorders of the Central Nervous System 7,5 biomedica Immunology ,00 Pagina 5 di 244

6 58 RF TRANSCRANIAL STIMULATION FOR INDUCING SLEEP: Effectiveness of tdcs and TMS techniques 7,5 biomedica Integrative, Functional, and Cognitive Neuroscience ,00 59 RF Mechanisms of immune surveillance of prostate cancer by CD1d restricted invariant NKT cells 7,5 biomedica Immunology ,00 60 RF Impact of engineered nanoparticles on reproductive health and embryonic development 7,5 biomedica Bioengineering Sciences and Technologies ,00 61 RF Randomized, multi center, open label, study of monotherapy with darunavir/ritonavir or lopinavir/ritonavir vs. standard of care in virologically suppressed HIV infected patients. 7,5 clinico assistenziale AS and Related Research 62 RF DESIGN OF A CLINICAL TRIAL USING CD133 LV(U7) 7,5 clinico assistenziale Genes, Genomes and ,00 63 RF Motor neuron death in Spinal Muscular Atrophy (SMA): new animal models and innovative therapeutic strategies 7,5 biomedica Brain Disorders and ,00 64 RF Lentiviral vectors and cell permeable peptides against Ras GRF and ERK signalling to treat L DOPA induced Dyskinesia 7,5 biomedica Molecular, Cellular, and Developmental Neuroscience 65 RF BONE MARROW AS AN ALTERNATIVE SITE FOR ISLET TRANSPLANTATION IN PATIENTS WITH TYPE 1 DIABETES 7,5 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences 66 RF DISEASE MODIFIERS AND NOVEL THERAPEUTIC TARGETS FOR ALTERED TISSUE REPAIR IN DYSTROPHIC EPERMOLYSIS BULLOSA 7,67 biomedica Musculoskeletal, Oral and Skin Sciences ,00 67 RF Chronic rejection in kidney transplantation: identification of new diagnostics targets 7,67 biomedica Immunology ,00 68 GR Beyond the use of autologous graft for urethral stricture repair: a novel application of stem cell in urethral tissue reconstruction. 7,75 clinico assistenziale Bioengineering Sciences and Technologies ,00 Pagina 6 di 244

7 69 GR Innovative approaches for diagnosis and treatment of B cell Chronic Lymphocytic Leukemia 7,75 clinico assistenziale Oncology 2 Clinical ,00 70 RF A novel 3D bioreactor for in vitro platelet production: a translational research strategy to support platelet supply problems in patients undergoing chemotherapy and/or receiving autologous stem cells. 7,75 biomedica Oncology 2 Clinical ,00 71 RF Combined Gene and Cell Therapy Approaches for the Treatment of Primary Immunodeficiencies 7,75 biomedica Genes, Genomes and ,00 72 RF Induction of long term synaptic plasticity in the human cerebellum by repetitive TMS: cellular mechanisms and implications for rehabilitation in ataxia 7,75 biomedica Integrative, Functional, and Cognitive Neuroscience ,00 73 RF Role of protein misfolding in the pathogenesis of Niemann Pick type C disease: a possible therapeutic target 7,84 biomedica Brain Disorders and ,00 74 RF Impact of Modified Intention to Treat Reporting on Treatment Effect in Metaanalyses: A Meta Epidemiological Study 8 clinico assistenziale Healthcare Delivery and Methodologies ,00 75 GR Dosimetric and methodological evaluation of the novel PET amyloid tracer 18F FDDNP 8 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering ,00 76 RF Use of nanoparticles overcoming the blood brain barrier in the treatment of the mouse model of the Krabbe Disease severe form. 8 biomedica Molecular, Cellular, and Developmental Neuroscience ,00 77 RF Isolated Hemihyperplasia, a pediatric cancer risk disease: search for genetic/epigenetic mechanisms involved in its pathogenesis 8 biomedica Genes, Genomes and ,00 78 RF Population based comparisons of cancer burden indicators 8 clinico assistenziale Population Sciences and Epidemiology ,00 79 RF Study of the molecular, biochemical and metabolic mechanisms involved in the cardioprotective effect of T3 8 biomedica Cardiovascular and ,00 80 GR Functional characterization of the circulating B cell compartment in rheumatoid arthritis: relationship with clinical remission and sub clinical disease activity 8 biomedica Musculoskeletal, Oral and Skin Sciences ,00 Pagina 7 di 244

8 81 GR The relationship among food, mycotoxins, gastrointestinal disorders and autism: a multidisciplinary approach for the molecular investigation. 8 biomedica Brain Disorders and ,00 82 RF Resistance to kinase Inhibitors in cancer therapy and in target validation 8 biomedica Oncology 1 Basic 83 RF Role of mitochondrial dynamics in myogenesis and in the therapeutic action of Nitric Oxide in muscular dystrophy 8 biomedica Musculoskeletal, Oral and Skin Sciences ,00 84 RF Phospholipid homeostasis and endosomal dynamics in neurodegenerative disorders of the central and peripheral nervous system 8 biomedica Molecular, Cellular, and Developmental Neuroscience ,00 85 RF Modeling glioma progression and oncogene addiction in vivo to identify and challenge new therapeutic targets 8 biomedica Oncology 1 Basic ,00 86 RF Gene therapy for beta thalassemia: studies of efficacy and safety 8 biomedica Genes, Genomes and ,00 87 RF Enhanced cell therapy of peripheral artery disease: improving survival and engraftment of transplanted endothelial cells by cell protection from oxidative stress. 8 biomedica Vascular and Hematology ,00 88 RF Platelet Rich Plasma, from clinical application to research and back: a new nonsurgical bioactive treatment for knee cartilage degeneration and osteoarthritis. 8 clinico assistenziale Musculoskeletal, Oral and Skin Sciences 89 RF models of atlastin function and dysfunction 8 biomedica Cell Biology ,00 90 RF The Role of Adipose Triglyceride Lipase (ATGL) in the Intracellular Muscle and Adipocyte Lipid Metabolism: the Model of Neutral Lipid Storage Disease with Myopathy (NLSDM) 8 biomedica Musculoskeletal, Oral and Skin Sciences ,00 91 RF LONG TERM PROGNOSIS OF OLDER PATIENTS AFTER HOSPITAL ADMISSION: ROLE OF PHYSICAL PERFORMANCE MEASURES, INFLAMMATORY MARKERS AND ADMINISTRATIVE DATA 8 clinico assistenziale Biology of Development and Aging ,00 92 RF Mitochondrial Carrier Diseases: Clinical prevalence, study of mechanisms, and possible therapies 8 biomedica Brain Disorders and ,00 Pagina 8 di 244

9 93 GR Quantitative proteomics to decipher the molecular code of protein methylation: the dynamic methylome dissected by MS and its role in cancer 8,17 biomedica Biological Chemistry and Macromolecular Biophysics ,00 94 RF A POTENTIAL IRON LIP METABOLISM CONNECTION REVEALED BY STUDIES OF HEPCIN REGULATION: RELEVANCE TO IRON DISORDERS AND METABOLIC SYNDROME 8,17 biomedica Vascular and Hematology , RF Dissecting the Role of Autophagy in HCV induced Steatosis 8,17 biomedica Infectious Diseases and Microbiology GR Folate metabolism, epigenetics, and Alzheimer s disease 8,25 biomedica Brain Disorders and , ,00 97 RF The role of alloreactive natural killer (NK) cells in children with hematological malignancies given a T cell depleted haematopoietic stem cell transplantation (HSCT) from an HLA disparate relative. 8,25 biomedica Oncology 2 Clinical ,00 98 RF New and emerging vector borne infectious diseases in Italy: epidemiology, surveillance, diagnosis and impact on the safety of blood and organ donations. 8,25 clinico assistenziale Infectious Diseases and Microbiology ,00 99 RF Cortical stimulation in the study of time processing and anosognosia in brain damaged patients 8,25 clinico assistenziale Brain Disorders and , GR Gene therapy for inborn errors of metabolism 8,25 biomedica Genes, Genomes and GR NEurocontrolled MEchatronic prosthesis (NEMESIS) 8,25 biomedica Emerging Technologies and Training in Neurosciences GR Subthalamic Nucleus Deep Brain Stimulation in Tourette s Syndrome 8,25 clinico assistenziale Brain Disorders and , , , RF Objective diagnosis of the hearing functionality and of the hearing loss susceptibility in workers exposed to noise and/or ototoxic agents, by development of advanced techniques for the acquisition and analysis of otoacoustic emissions. Evaluation of the 8,25 biomedica Bioengineering Sciences and Technologies ,00 Pagina 9 di 244

10 104 RF Ita MNGIE: An Italian network for MNGIE epidemiology, molecular mechanisms and enzyme replacement therapy by stem cell transplant 8,25 clinico assistenziale Genes, Genomes and , RF Sensori motor Integration. Physiology and Pathophysiology. 8,34 biomedica Integrative, Functional, and Cognitive Neuroscience RF Prevention of anthracycline induced cardiotoxicity: a multicentre randomized trial 8,5 clinico assistenziale Cardiovascular and , , RF Borrelia infection and mantle cell lymphoma: a pathogenic association of clinicotherapeutic relevance 8,5 biomedica Oncology 1 Basic , RF A sequencing based genome wide association scan for autoimmunity in Sardinia 8,5 biomedica Genes, Genomes and , RF Right ventricular adaptiation in pulmonary arterial hypertension: the interplay between shape and myocardial injury 8,5 clinico assistenziale Cardiovascular and , RF Pharmacological enhancement of tumor cell death by soluble or membrane TRAIL and SMAC mimetics 8,5 biomedica Oncology 2 Clinical , RF SEARCHING NEW THERAPEUTIC TARGETS IN CHRONIC LYMPHOCYTIC LEUKEMIA (CLL) BY DISSECTING TUMOR CELL/ MICROENVIRONMENT INTERACTIONS 8,5 biomedica Oncology 1 Basic , RF Italian Network of Genetic Isolates (INGI): identification of genetic and environmental risk factors for cardiovascular disorders 8,5 biomedica Genes, Genomes and 113 RF DRUG TRANSPORTERS AND RESISTANCE TO TREATMENT OF OVARIAN CARCINOMA 8,5 biomedica Oncology 1 Basic , GR B cell reconstitution upon gene therapy in WAS patients from the first clinical trial with lentiviral vectors 8,5 biomedica Immunology , RF Towards a functional classification of human melanoma: dissecting the altered intracellular signaling profile by phosphoproteomics approaches. 8,5 biomedica Oncology 1 Basic ,00 Pagina 10 di 244

11 116 GR The Role of Endothelial Mineralocorticoid Receptors in Vascular Inflammation and Atherosclerosis 8,5 biomedica Vascular and Hematology , GR MULTISCIPLINARY TRANSLATIONAL BIOMEDICS APPROACH TO BICUSP AORTIC VALVE RELATED AORTOPATHY FOR THE DEVELOPMENT OF NEW CLINICAL DIAGNOSTIC AND PROGNOSTIC TOOLS 8,5 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , GR Theta band oscillations and resonance in the cerebellum: implications for cerebellar ataxia 8,5 biomedica Integrative, Functional, and Cognitive Neuroscience , RF Studies on the functional role and regulation of a restricted signature of micrornas in acute myeloid leukemia 8,5 biomedica Oncology 1 Basic , RF Growing Old with Less Disease Enhancing Neurofunctions (GOLDEN) study. A cohort study over young and old adults from general population 8,5 clinico assistenziale Biology of Development and Aging , RF Development of novel drugs counteracting amyloid driven organ damage in systemic amyloidosis 8,5 biomedica Biological Chemistry and Macromolecular Biophysics , RF Context specific response to proteotoxicity and its role in degenerative diseases 8,5 biomedica Cell Biology 123 GR Tripartite Motif (TRIM) 22 Mediated Restriction Of HIV 1 And Other Pathogenic Human Retroviruses: Investigation Of The Molecular Interactions For Novel Therapeutic Approaches 8,5 biomedica AS and Related Research , RF Cognitive reserve, brain reserve, and neuroplasticity in Alzheimer's disease 8,5 clinico assistenziale Brain Disorders and 125 GR GENETIC AND FUNCTIONAL ANALYSIS OF COPY NUMBER VARIATIONS (CNVs) AFFECTING ION CHANNEL GENES IN FAMILIAL IOPATHIC GENERALIZED EPILEPSY 8,5 biomedica Genes, Genomes and , RF Biomaterials to promote nerve regeneration: towards clinical trials. 8,5 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering ,00 Pagina 11 di 244

12 127 RF DEVELOPMENT OF DRUGS SELECTIVELY ACTIVATING Na+/Ca2+ EXCHANGER ISOFORMS TO TREAT CEREBRAL ISCHEMIA 8,5 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Development of guidelines, management systems and new methodologies for GMOs traceability, own checks procedures and official control in the food and feed supply chain with respect to EU legal requirements 8,67 biomedica Veterinary Food Safety FOSA , RF Gene expression profiling in juvenile idiopathic arthritis: integrated analysis of clinical, imaging and molecular features 8,67 biomedica Musculoskeletal, Oral and Skin Sciences 130 RF A renal transplant model designed to identify non invasive kidney injury biomarkers and urinary exosomes of acute rejection and nephrotoxicity. A study in a swine lymphocyte antigens (SLA) defined strain of pigs 8,75 biomedica Immunology , GR Advanced diagnostics and innovative procedures for diagnosis and therapy in striated muscle channelopathies 8,75 biomedica Musculoskeletal, Oral and Skin Sciences , RF Contribution of Urokinase Plasminogen Activator to HIV and Tumor Derived Stroma Driving Polarization of Macrophages 8,75 biomedica AS and Related Research , GR Sudden cardiac death during myocardial ischemia: unmasking genetic factors contributing to ventricular fibrillation 8,75 biomedica Genes, Genomes and , RF DEVELOPMENT OF BIOMARKERS BY LOW INVASIVE METHODS AND THEIR VALATION IN DUCHENNE MUSCULAR DYSTROPHY AND COLLAGEN 6 MYOPATHIES TO EVALUATE MECHANISM BASED PHARMACOLOGICAL THERAPY 8,84 biomedica Musculoskeletal, Oral and Skin Sciences , RF Potentiating clinical and immunological effects of chemotherapy by neutralizing acidic ph at tumor site: a phase II randomized study in melanoma patients 8,84 clinico assistenziale Oncology 2 Clinical , RF STUDIES ON THE INVOLVEMENT OF GENETIC, EPIGENETIC AND ENVRINOMENTAL FACTORS IN THE PATHOGENESIS OF CONGENITAL HYPOTHYROISM. NOVEL PERSPECTIVES FOR THE MANAGEMENT OF A LARGELY UNEXPLAINED DISORDER 8,84 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences ,00 Pagina 12 di 244

13 137 GR MECHANISMS AND EFFECTS OF THE DNA DAMAGE RESPONSE IN THE HEART AND NOVEL MOLECULAR APPROACHES TO ENHANCE CARDIOMYOCYTE REPAIR 9 biomedica Cardiovascular and , GR Elaboration and pre clinical validation of a combinatorial immunotherapeutic strategy for the dual targeting of tumour vessels and cancer initiating cells 9 biomedica Oncology 1 Basic , RF On demand release of antimicrobial agents on biofilm colonized urinary catheters by drug functionalized polymer nanoparticles and liposomes 9 biomedica Infectious Diseases and Microbiology 140 GR Innovative screening tool for allergic diseases in children: impact on clinical outcome, quality of life and socio economic burden. 9 clinico assistenziale Healthcare Delivery and Methodologies 141 GR THE PREDICTOMIC STUDY: METABOLOMIC APPROACH IN PHENOTYPING AND DRUG RESPONSE PREDICTION IN PEDIATRIC RESPIRATORY DISESASES 9 biomedica Cardiovascular and , GR Mouse and human induced pluripotent stem cells for myocardial diseases. 9 biomedica Cardiovascular and 143 RF The role of B Cell Receptor stimulation in the pathogenesis of Chronic Lymphocytic Leukemia 9 biomedica Oncology 1 Basic , GR Mesenchymal Stem Cells and Inflammatory Bowel Disease 9 biomedica Digestive, Kidney and Urological Systems , RF Role of natural killer cells in the pathogenesis and progression of multiple sclerosis 9 biomedica Immunology , RF RIFF Project Risk and Incidence of Fragility Fractures (RIFF) in Italy for the updating and validation of the Italian version of FRAX and supporting the Nation Registry of Fragility Fractures 9 clinico assistenziale Population Sciences and Epidemiology 147 GR Reorganization of the macrophage epigenome during sustained inflammation and its functional implications. 9 biomedica Immunology , GR "My Mind" Project: the effects of cognitive training for elderly 9 clinico assistenziale Healthcare Delivery and Methodologies Pagina 13 di 244

14 149 RF Ultra deep pyrosequencing as a tool to evaluate the genetic variability of viruses, and to define markers of clinical relevance: from applied research to routine diagnosis 9 clinico assistenziale Infectious Diseases and Microbiology , RF Role of kinases and phosphatases in controlling progression through mitosis 9 biomedica Cell Biology , RF Endothelial injury and repair in diabetes. The development of a non invasive multimarker index for "vascular competence". 9 biomedica Vascular and Hematology , GR Modulation of ER stress as a therapeutic approach in hereditary neuropathies 9 biomedica Molecular, Cellular, and Developmental Neuroscience 153 GR Exploring the role of mitochondrial dynamics in the regulation of T cell homeostasis associated with MS 9 biomedica Cell Biology , GR Role of kidney, breast and lung cancer stem cells in bone metastases 9 biomedica Oncology 1 Basic , RF MicroRNAs as molecular markers of susceptibility to Mycobacterium tuberculosis infection and responsiveness to vaccination in IRF 8 deficient mouse model. 9 biomedica Infectious Diseases and Microbiology , GR Regenerative potential of the proinflammatory cytokine interleukin 22: towards new therapeutic approaches for diabetic ulcer treatment 9 biomedica Musculoskeletal, Oral and Skin Sciences , GR UNRAVELING THE PATHOGENESIS OF FAMILIAL MYELOPROLIFERATIVE NEOPLASMS: ENTIFICATION OF THE INHERITED PREDISPOSITION THROUGH GENOME WE LINKAGE ANALYSIS, GENOME WE ASSOCIATION STUDIES AND NEXT GENERATION SEQUENCING 9 biomedica Vascular and Hematology , GR Renal Committed Embryonic Stem Cells to Promote Kidney Regeneration 9 biomedica Digestive, Kidney and Urological Systems , RF Poly(ADPribosyl)ation as a member of the regulators of mitochondrial function, implication in mitochondrial disorders 9 biomedica Brain Disorders and , GR Therapeutic Inhibition of Classical and Lectin Pathways of Complement to Prevent Local and Systemic effects of Renal Ischemia Reperfusion Injury. 9 biomedica Digestive, Kidney and Urological Systems ,00 Pagina 14 di 244

15 161 GR Memory Enhancement by Advanced Non Invasive Brain Stimulation: A project on Neuro Rehabilitation of patients with memory diseases. 9 biomedica Brain Disorders and , RF Proteomic analysis of newborn's saliva. 9 biomedica Biological Chemistry and Macromolecular Biophysics , GR PATHOGENESIS OF COENZYME Q10 DEFICIENCY 9 biomedica Genes, Genomes and , RF Validation of the micronucleus assay in buccal exfoliated cells as a tool for biomonitoring DNA damage in human populations and predicting cancer in healthy subjects. 9 biomedica Population Sciences and Epidemiology , RF VRehab Virtual Reality in the Assessment and TeleRehabilitation of Parkinson s Disease and Post Stroke Disabilities 9 clinico assistenziale Emerging Technologies and Training in Neurosciences , GR ips derived neural stem cells for Spinal Muscular Atrophy Therapy (SMAThera) 9 biomedica Brain Disorders and , RF Functional relevance of Natural Killer cells in the pathogenesis of primary sclerosing cholangitis 9 biomedica Immunology , RF Converting the kinetochore spindle contact into an anticancer drug target 9 biomedica Cell Biology , RF Neuromodulation of synaptic plasticity in the cerebellum and its implications for cerebro cerebellar dysfunction in autism 9 biomedica Integrative, Functional, and Cognitive Neuroscience , RF Cell permeable JNK3 inhibitor peptides as drug delivery system to prevent neurodegeneration in Alzheimer disease 9 biomedica Brain Disorders and , GR Mucosal Dendritic Cells Anti inflammatory Phenotype Induction by Polyphenols Oral Administration: Effects on IBD Therapies. 9 biomedica Digestive, Kidney and Urological Systems , GR Modulation of MicroRNA expression by microenvironmental stimuli in Chronic Lymphocytic Leukemia: implication for therapy 9 biomedica Oncology 1 Basic ,00 Pagina 15 di 244

16 173 RF Optimization of ex vivo generation of human erythroid cells for transfusion 9 biomedica Vascular and Hematology , RF Multimodality approach in epilepsy 9 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Host cell interactions with replicating or non replicating Mycobacterium tuberculosis as a preclinical model to disclose new targets of immunointervention for tuberculosis 9 biomedica Cardiovascular and , RF Inflammation and neuroretinal injury in Diabetic Retinopathy: possible role of Pigment Epithelium Derived Factor as therapeutic agent 9 biomedica Cell Biology , RF Coupling Soluble and Cellular Diagnostics with Advanced Therapeutics for Bone Metastasis 9,17 biomedica Oncology 2 Clinical 178 GR The role of leukaemia specific mutant of NPM1 in activation of Wnt signalling, retinoic acid sensitivity in NPMc+AML 9,25 biomedica Vascular and Hematology , GR A new Cardiopulmonary By Pass system that minimizes haemodilution, haemolysis and systemic inflammation. Effects on organ damage and surgical outcome 9,25 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , RF GONARTHRITIS TREATMENT WITH PLATELET RICH PLASM (PRP): ANALYSIS OF JOINT MICROENVIRONMENT AND PRP GROWTH FACTORS TO PREDICT THE CLINICAL OUTCOME 9,25 biomedica Musculoskeletal, Oral and Skin Sciences , RF Identification of immunosuppressive biomarkers in peripheral blood and tissues of patients with melanoma 9,25 biomedica Oncology 2 Clinical , GR Relationship between sleep disordered breathing and clinical phenotype in PD: paroxysmal motor behavioural manifestations, sleepiness and cognition. Uncover the effect by treating sleep apnoea. 9,25 clinico assistenziale Brain Disorders and , GR Safety, traceability and reliability of collection, processing and transplantation of haematopoietic stem cells (HSCs) and therapeutic cells (TCs): integrated procedures and tools to support operations, clinical care and banking 9,25 clinico assistenziale Vascular and Hematology ,00 Pagina 16 di 244

17 184 GR CO TRANSPLANTATION OF MESENCHYMAL STEM CELLS AND PANCREATIC ISLETS: A PRECLINICAL STUDY TO EVALUATE THE EFFECT ON ENGRAFTMENT AND IMMUNORESPONSE AFTER CO LOCALIZATION IN THE BONE MARROW 9,25 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR CLASSICAL AND INNOVATIVE STRATEGIES FOR THE ENTIFICATION OF GENETIC DEFECTS AT THE BASIS OF RARE FORMS OF PARTIAL EPILEPSY 9,25 biomedica Genes, Genomes and , GR Straight and curved walking in Parkinson s disease: basic mechanisms, pathophysiology and rehabilitation interventions 9,25 biomedica Musculoskeletal, Oral and Skin Sciences , GR DEVELOPMENT OF NON INVASIVE STRATEGIES FOR PRENATAL DIAGNOSIS OF RARE DISEASES BASED ON SURFACE PLASMON RESONANCE (SPR) IMAGING, PEPTE NUCLEIC ACS PROBES AND PCR FREE HYBRIZATION 9,5 biomedica Genes, Genomes and , RF Novel mutated oncogenes in multiple myeloma 9,5 biomedica Oncology 1 Basic GR Identification of functional role of potassium channels in primary aldosteronism 9,5 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , , RF Endothelial cell cell junctions:targets for vascular normalization and therapeutic intervention in tumors 9,5 biomedica Oncology 1 Basic RF Food and environmental safety: the problem of the endocrine disruptors 9,5 biomedica Veterinary Food Safety FOSA GR Promoting and imaging restoration of brain function in Multiple Sclerosis 9,5 biomedica Brain Disorders and , RF Functional analysis of NCAM in acute myeloid leukemia 9,5 biomedica Vascular and Hematology , RF Role of the RNA binding protein Sam68 in the regulation of SMN2 splicing: implications for novel therapeutic approaches to Spinal Muscular Atrophy 9,5 biomedica Genes, Genomes and , GR Post translational modifications induced by reactive species in tumor microenvironment: a new pathway to tumor immune escape 9,5 biomedica Immunology ,00 Pagina 17 di 244

18 196 RF THE ROLE OF GENDER IN PARKINSON'S DISEASE: SEX SPECIFIC THERAPEUTIC APPROACH BASED ON NEUROACTIVE STEROS 9,5 biomedica Brain Disorders and , RF Group I metabotropic glutamate receptors as possible targets for innovative pharmacological treatment of amyotrophic lateral sclerosis 9,5 biomedica Brain Disorders and , RF Role of nutrients involved in one carbon metabolism in the development of different molecular subtypes of breast cancer in the ORDET cohort 9,5 clinico assistenziale Population Sciences and Epidemiology , GR An open label, single arm, phase II, prospective, pilot study of tocilizumab in patients with Erdheim Chester disease 9,5 clinico assistenziale Immunology , RF Immunesurveillance of leukaemia by CD1 restricted T cells specific for self lipid antigens 9,5 biomedica Immunology , GR Exploiting oncogene addiction and premature senescence to design novel therapeutic strategies for the treatment of cancer 9,5 biomedica Cell Biology , RF A novel endoscopic surveillance protocol in patients with Barrett s esophagus to predict the progression to esophageal adenocarcinoma 9,5 biomedica Oncology 2 Clinical , RF Risk evaluation of human exposure to Mycobacterium avium subsp. paratuberculosis (Map) and comparative analysis of strains of human and animal origin 9,5 biomedica Veterinary Food Safety FOSA , GR Improving dementia care using early counseling and support for caregivers. 9,5 clinico assistenziale Risk, Prevention and Health Behavior , RF Cell therapy with different types of IL 10 producing regulatory T cells: pre clinical comparative validation of efficacy 9,5 biomedica Oncology 2 Clinical 206 RF Identification of new prognostic factors for disease outcome in a regional cohort of patients with B cell chronic lymphocytic leukemia (B CLL) 9,5 biomedica Vascular and Hematology , RF Role of the regulatory pathways in the pathogenesis of T cell dysfunction in chronic HBV and HCV infections: diagnostic and therapeutic implications 9,5 biomedica Infectious Diseases and Microbiology Pagina 18 di 244

19 208 RF Rehabilitation of Acalculia 9,5 clinico assistenziale Brain Disorders and , RF Physiopathology studies on the increased thyroid cancer incidence in the volcanic areas of Sicily 9,5 biomedica Oncology 1 Basic , RF Biomacromolecular characterization and multi resolution modeling in structural genomics/proteomics. Development of a comprehensive facility, and application to the fibrin(ogen) integrins cell extracellular matrix interactions model system. 9,5 biomedica Biological Chemistry and Macromolecular Biophysics , RF Effects of Hp(2 20) peptide on cutaneous, corneal, conjunctival and gastric wound healing 9,5 biomedica Veterinary Animal Health ANHE , RF Protection against influenza infection: define persistence and cross reactivity of protective immune status induced by the natural infection and vaccination; analysis of the immunological milieu in human ex vivo models. 9,5 biomedica Infectious Diseases and Microbiology , RF Development of a cerebellar connectivity EEG index to evaluate cerebro cerebellar interactions. 9,5 biomedica Brain Disorders and , RF TOTAL PANCREATECTOMY WITH ISLET AUTOTRANSPLANTATION AS A SUPERIOR ALTERNATIVE TO PANCREATODUODENECTOMY IN PATIENTS AT VERY HIGH RISK OF COMPLICATIONS OF THE PANCREATIC ANASTOMOSIS: A SINGLE CENTER PROSPECTIC RANDOMISED CLINICAL TRIAL 9,5 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering 215 RF Role of the immune system in bone resorption: the mineralized matrix as an osteoclast activating danger signal 9,5 biomedica Musculoskeletal, Oral and Skin Sciences , RF Understanding the interactions between retroviral vectors and the genome of human somatic stem cells 9,5 biomedica Genes, Genomes and , RF Dynamic interplay between innate and acquired immune response and pandemic influenza A H1N virus evolution 9,67 biomedica Infectious Diseases and Microbiology 218 GR Towards an innovative therapy of Ectrodactyly Ectodermal dysplasia Clefting (EEC) syndrome using allele specific RNA silencing 9,67 biomedica Genes, Genomes and ,00 Pagina 19 di 244

20 219 GR New insights on the role of purinergic P2Y12 receptor in Multiple Sclerosis 9,75 biomedica Brain Disorders and , RF Monitoring of chimerism on sorted peripheral CD34+ cells in patients with acute leukemia receiving allogeneic bone marrow transplantation 9,75 clinico assistenziale Oncology 2 Clinical , RF ASSESSING BEST STRATEGIES FOR ADAPTIVE IMAGE GUED TOMOTHERAPY 9,75 biomedica Oncology 2 Clinical , GR Adenoviral gene transfer of donor specific MHC class II on Aire expressing mtec to induce allograft tolerance 9,75 biomedica Immunology , GR Multi site RCT comparing regional and general anaesthesia for effects on neurodevelopmental outcome in infants The GAS study 9,75 clinico assistenziale Brain Disorders and , GR Hunt for new disease genes in hereditary spastic paraplegia 9,75 biomedica Brain Disorders and 225 GR A PROSPECTIVE COMPARATIVE STUDY BETWEEN OPEN AND ROBOTIC ASSISTED LAPAROSCOPIC RADICAL PROSTATECTOMY FOR PATIENTS WITH ORGAN CONFINED PROSTATE CANCER. IMPACT OF SURGICAL APPROACH ON ONCOLOGICAL AND FUNCTIONAL RESULTS, PERI OPERATIVE PARAMETERS AND COSTS. 9,84 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , GR Role of Chromatin Remodeling in Germ Stem Cell Identity 10 biomedica Genes, Genomes and , GR A NEW MULTISCIPLINARY STRATEGY FOR DRUG DISCOVERY IN NEURODEGENERATIVE DISEASES 10 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Standardized Brain Imaging Database for the Evaluation of Semantic Memory Disorders and Cognitive Reserve in Mild Cognitive Impairment and Alzheimer's Disease (SBSMCR) 10 biomedica Brain Disorders and , GR Psychological consequences of cancer in elderly patients and their family 10 clinico assistenziale Oncology 2 Clinical ,00 Pagina 20 di 244

21 230 GR Investigating the molecular mechanisms leading to genome instability in tumours: analysis of role of the replication stress response and its potential for early diagnosis and target therapy of cancer 10 biomedica Oncology 1 Basic , RF Preclinical characterization and sequence optimization of a potent antimicrobial peptide for the development of a new drug for Cystic Fibrosis 10 biomedica Infectious Diseases and Microbiology , RF Role of HIV 1 infection on colorectal carcinoma onset and progression and development of novel therapeutic strategies 10 biomedica AS and Related Research , GR The molecular signature of liver autoimmunity: genome wide differences in epigenetics and copy number variations between monozygotic twins discordant for primary biliary cirrhosis 10 biomedica Digestive, Kidney and Urological Systems , GR Mechanism driven exploration of hormonal interventions for menopause and aging related cardiovascular diseases 10 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF "Tailored" Accreditation Model for Comprehensive Cancer Centers: validation through the applicability of the experimental OECI based model to the Network of Cancer IRCCS of Alleanza contro il Cancro 10 clinico assistenziale Healthcare Delivery and Methodologies 236 GR Service for detection of Pre psychoses: from genomics to phenomenology in a human/animal perspective 10 biomedica Brain Disorders and 237 RF IGF I isoforms and Breast Cancer 10 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Evaluation of cytochrome p450 2D6 and 2C19, ABCG1, ABCG2 polymorphisms in patients affected by chronic myeloid leukemia and their therapeutic implications 10 clinico assistenziale Oncology 2 Clinical , GR Role of Che 1 in DNA damage response 10 biomedica Oncology 1 Basic 240 GR Identification of immunological molecular patterns in atherosclerosis. 10 biomedica Vascular and Hematology ,00 Pagina 21 di 244

22 241 RF ANTIPLATELET TREATMENT FOR PREVENTION OF VASCULAR OUTCOMES IN PAD PATIENTS UNDERGOING PERIPHERAL REVASCULARIZATION. 10 clinico assistenziale Vascular and Hematology , GR Investigation of novel indicators of sleepiness in healthy subjects and in sleep disorders by simultaneous polysomnographic fmri techniques 10 biomedica Emerging Technologies and Training in Neurosciences , GR Development of a multifunction platform for telerehabilitation. 10 biomedica Healthcare Delivery and Methodologies , RF Study of the healthy benefits of anthocyanin dietary supplementation on obesity and cancer 10 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Development of a novel mouse model of B CLL: validation of p66shc as a prognostic marker and therapeutic target 10 biomedica Oncology 2 Clinical , GR Management of severe health care associated infections in high risk departments based on on line Infectious Diseases Specialists consulting: evaluation of efficacy and efficiency 10 clinico assistenziale Healthcare Delivery and Methodologies , GR The non oncotic properties of human serum albumin in liver cirrhosis: functional characterization, clinical application and therapeutic perspectives. 10 biomedica Digestive, Kidney and Urological Systems , RF Role of IL 2 family cytokines in the regulation of cell survival and gene expression of neoplastic B cells 10 biomedica Vascular and Hematology , GR The role of Gas6/RTK receptors in Rheumatoid Arthritis and Multiple Sclerosis: a patient and biological study 10 biomedica Immunology , RF Identification of a Polycystin 1/Nephrocystin 1 Complex: functional and biochemical studies in vitro and in vivo 10 biomedica Digestive, Kidney and Urological Systems 251 RF Identification of new biomarkers for metabolic syndrome associated with antipsychotic treatment 10 biomedica Biobehavioral and Behavioral Processes 252 RF From BioEngineering new tools for identification of early markers of respiratory and cardiac impairment in Duchenne Muscular Dystrophy 10 clinico assistenziale Musculoskeletal, Oral and Skin Sciences ,00 Pagina 22 di 244

23 253 RF Exome sequencing of familial Parkinson disease: fishing for new genes trough next generation sequencing 10 biomedica Genes, Genomes and 254 RF MOLECULAR AND PHARMACOLOGICAL CHARACTERIZATION OF TMEM16A (ANOCTAMIN 1) AS A NOVEL CHLORE CHANNEL 10 biomedica Cell Biology , RF The mevalonate pathway as a target of immune intervention in lymphoproliferative diseases and solid cancers 10 biomedica Oncology 2 Clinical , GR From hyperphenylalaninemia to mental retardation: the key role of serotonin. 10 biomedica Brain Disorders and , GR Proteins and genes in Frontotemporal lobar degeneration: old and novel players in neurodegeneration 10 biomedica Genes, Genomes and , RF A multidisciplinary approach to unravel the role of uromodulin in chronic diseases of the kidney 10 biomedica Digestive, Kidney and Urological Systems 259 RF MECHANISMS OF HCV PERSISTENCE IN THE HOST AND INDUCTION OF THE LYMPHOMAGENETIC PROCESS 10 biomedica Oncology 1 Basic , GR GENERATION AND TRANSPLANTATION OF GENETICALLY ENGINEERED NEURAL STEM CELLS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS 10 biomedica Brain Disorders and , RF Integrated approaches for the classification of variants of uncertain significance in BRCA genes. 10 biomedica Oncology 1 Basic , RF Combating Mitochondrial Disorders in cells, animal models and patients 10 biomedica Molecular, Cellular, and Developmental Neuroscience , RF A metagenomic approach to evaluate the influence of antimicrobial therapy on the selection of multi drug resistant clones responsible for health care associated infections in the Intensive Care Unit setting 10 biomedica Infectious Diseases and Microbiology , RF The role of necdin in the self renewal and activation of endogenous stem cells for the repair of dystrophic muscle 10 biomedica Musculoskeletal, Oral and Skin Sciences ,00 Pagina 23 di 244

24 265 RF Identification of self renewal programs in epidermal stem cells. 10 biomedica Musculoskeletal, Oral and Skin Sciences , GR Understanding the formation of hyperplastic lesions in human proliferative glomerulonephritis: role of endothelin in promoting podocyte migration 10 biomedica Digestive, Kidney and Urological Systems , RF Characteristics of persons with HIV/AS in Italy: a cross sectional study 10 clinico assistenziale AS and Related Research , RF Pathological relevance of B cell abnormalities and Epstein Barr virus infection in multiple sclerosis: focus on early brain lesions and cases with relapsing remitting and aggressive disease. 10 biomedica Brain Disorders and , RF Ovarian stimulation for infertility treatment and cancer risk: an italian cohort study 10 clinico assistenziale Population Sciences and Epidemiology , RF Role and mechanisms of the homeprotein Prep1 in pathogenesis and diagnosis of human type II diabetes and obesity. 10,17 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences 271 GR RECESSIVE SPINOCEREBELLAR ATAXIAS: AN INTEGRATED CLINICAL, NEURORADIOLOGICAL, BIOCHEMICAL AND GENETIC APPROACH FOR THE ENTIFICATION OF NEW PHENOTYPES AND POSSIBLE BIOMARKERS 10,25 clinico assistenziale Brain Disorders and , GR Immunological biomarkers predictive of successful antiviral therapy in chronic HCV infection 10,25 biomedica Immunology 273 GR Integration of deep and low coverage sequencing data in a genome wide association study for HbF levels and its implication in the clinical severity of betathalassemia. 10,25 biomedica Genes, Genomes and 274 GR THERAPEUTIC APPROACHES IN FABRY DISEASE AND GM1 GANGLIOSOSIS CAUSED BY RNA AND CONFORMATIONAL DEFECTS 10,25 biomedica Biobehavioral and Behavioral Processes , GR Optimization of selection criteria for patients affected by metastatic HER2 overexpressing breast cancers eligible for a frontline treatment with Trastuzumab or Lapatinib 10,25 clinico assistenziale Oncology 2 Clinical ,00 Pagina 24 di 244

25 276 GR Orienting of spatial attention in complex environments: intra regional activation and inter regional connectivity in the intact and the damaged human brain 10,25 biomedica Brain Disorders and , GR Molecular and functional characterization of a cell adhesion molecule in a novel ectodermal dysplasia syndrome and in cancer 10,25 biomedica Genes, Genomes and , GR Preoperative TPF chemotherapy in locally advanced resectable oral cavity squamous cell cancer in order to improve pathological complete response rate: a phase II study 10,25 clinico assistenziale Oncology 2 Clinical , RF ADVANCED PRODUCTS AND PROTOCOLS FOR THE PREVENTION AND TREATMENT OF DIABETIC FOOT ULCERS 10,25 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering 280 RF WNT signaling and clock genes in the pathogenesis of Bipolar Disorder 10,25 biomedica Brain Disorders and , RF The role of the extracellular matrix protein EMILIN1 in tumor growth and lymphatic spread 10,34 biomedica Oncology 1 Basic , RF Can a heart failure specific cardiac rehabilitation program decrease hospitalizations and improve outcomes in patients with chronic advanced heart failure? 10,34 clinico assistenziale Healthcare Delivery and Methodologies , RF THE ROLE OF ADIPOKINES OF THE CTRP FAMILY IN CAUSING ARTERIAL HYPERTENSION AND PREMATURE PATHOLOGY OF THE CEREBROVASCULAR SYSTEM 10,34 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Transposon based genetic screening for non coding RNAs involved in colorectal cancer metastasis 10,5 biomedica Genes, Genomes and , RF Reducing unjustified consumer alarmism by mapping, monitoring and improving food safety communication in the media 10,5 clinico assistenziale Veterinary Food Safety FOSA , GR Molecular characterization of glioblastoma stem cell contribution to tumor angiogenesis to design novel therapies for glioblastoma treatment 10,5 biomedica Oncology 1 Basic ,00 Pagina 25 di 244

26 GR Inflammation and immune responses in vitamin D deficient patients. 10,5 biomedica Musculoskeletal, Oral and Skin Sciences RF Cancer survivorship: A new paradigm of care 10,5 clinico assistenziale Healthcare Delivery and Methodologies RF Vertical viral transmission as a frequent cause of autism 10,5 biomedica Brain Disorders and , , RF IMPLEMENTATION OF INTERPERSONAL PSYCHOTHERAPY IN A COLLABORATIVE STEPPED CARE MODEL 10,5 clinico assistenziale Healthcare Delivery and Methodologies , RF Biological Characterization, Molecular Diagnosis and Targeted Circumvention of Leukemia Immunoediting after Hematopoietic Stem Cell Transplantation 10,5 biomedica Oncology 2 Clinical 292 GR Involvement of dysregulated OPG/RANK/RANKL axis in atherogenesis and acute coronary syndromes 10,5 biomedica Vascular and Hematology , RF The RNA Interactome of TLS/FUS as a novel approach to understand RNA dysmetabolism in ALS 10,5 biomedica Brain Disorders and , GR Impact of TACE/Timp3 dyad in neurovascular disorders: a proteomic investigation 10,5 biomedica Biological Chemistry and Macromolecular Biophysics 295 GR Treatment of Neurological Impairment in Lysosomal Storage Diseases by the Use of Neural Stem Cells 10,5 biomedica Brain Disorders and , GR Dissecting the role of plasmacytoid dendritic cells in cancer. 10,5 biomedica Immunology 297 RF Non invasive biomarkers of diagnosis, recurrence and tumor response in colon and rectal cancer 10,5 biomedica Oncology 2 Clinical , RF Adult human stem cells as a source for kidney and liver regeneration 10,5 biomedica Digestive, Kidney and Urological Systems , GR The extracellular matrix protein EMILIN1 as a determinant in the pathogenesis of lymphedema: a basis for new therapeutic approaches 10,5 biomedica Vascular and Hematology ,00 Pagina 26 di 244

27 300 GR Hom Sweet Hom: Identification and control of the determinants of the homoplasmic shift of mitochondrial DNA mutations to drive benign tumorigenesis 10,5 biomedica Oncology 1 Basic , RF Influence of Telomere Length on the Risk of Ischemic Stroke and Prediction of Poststroke Recurrence 10,5 biomedica Brain Disorders and , GR Clinical data driven research of new stem cell modulating agents for vascular repair in diabetes 10,5 biomedica Cardiovascular and , RF The mother in the cord: the immune privilege translated to the stem cells transplant setting 10,5 biomedica Immunology , RF Characterization of the role of Polycomb post translational modifications and of the recruiting factor Jarid2 in differentiation and cancer. 10,5 biomedica Genes, Genomes and , GR LYMPHOCYTE ACTIVATION AND HOMING DEFECTS IN THE WHIM SYNDROME 10,5 biomedica Immunology , RF Set up of new procedures for selective allo depletion preserving regulatory T cells: a comprehensive approach to prevent both Graft Versus Host Disease and Severe infections in Hematopoietic Stem Cells Transplantation. 10,5 biomedica Immunology , RF A translational approach to restrain recurrence of early breast cancer 10,5 biomedica Oncology 1 Basic , RF G15 Protein as a Therapeutic Target in Pancreas Cancer 10,5 biomedica Cell Biology , RF Mapping the epigenome of tumor cells: identifying causes, markers and targets for new epigenetic therapies 10,5 biomedica Oncology 1 Basic , RF Induced pluripotent stem cells as a potential source of autologous neural stem cells for multiple sclerosis therapy 10,5 biomedica Brain Disorders and , RF Role of microrna 221 and microrna 222 in the pathogenesis of muscular dystrophies 10,5 biomedica Musculoskeletal, Oral and Skin Sciences ,00 Pagina 27 di 244

28 312 RF An integrated platform for molecular and cellular studies in chronic myeloproliferative neoplasms to identify novel biomarkers and targets for therapy 10,5 biomedica Oncology 1 Basic , RF A PROSPECTIVE STUDY TO EVALUATE THE INFLUENCE OF GENETIC VARIATION OF THE ORGANIC CATION AND MULTRUG AND TOXIN EXTRUSION TRANSPORTERS ON THE RESPONSE TO METFORMIN IN DRUG NAÏVE TYPE 2 DIABETIC PATIENTS 10,5 biomedica Genes, Genomes and , GR Adenosine A2A receptors as potential therapeutic targets in Niemann Pick type C disease 10,5 biomedica Brain Disorders and , RF Role of functional polymorphisms of the brain serotonin synthesizing enzyme TPH2 in treatment resistant depression: from human single gene mutations to mouse models. 10,5 biomedica Brain Disorders and , RF High throughput copy number variation discovery in oculo auriculo vertebral spectrum: identification of disease causing genes and loci and implications in clinical diagnostics 10,5 biomedica Genes, Genomes and , GR Novel drugs for targeted anticancer therapy 10,5 biomedica Oncology 1 Basic , RF Aberrant gene expression and facioscapulohumeral muscular dystrophy (FSHD): role of non protein coding RNAs and the epigenome. 10,5 biomedica Genes, Genomes and 319 RF Natural Control of HIV 1 Infection in the Absence of Antiretroviral Therapy. A Prospective Multi cohort Study of HIV 1+ Long Term Nonprogressors (LTNP) and Viral Controllers. 10,67 biomedica AS and Related Research 320 RF Evaluation of anthocyanin mechanisms of action in diabetes: effects on endothelial dysfunction and on cardiovascular markers in human 10,67 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Use of saliva as biological matrix for non invasive screening of oral cancer ONCOSAL (ONCOlogical Diagnosis by SALiva) 10,75 biomedica Oncology 2 Clinical , GR Oxidative Stress in Multiple Sclerosis disease progression. A proteomic and redox proteomic analysis 10,75 biomedica Brain Disorders and ,00 Pagina 28 di 244

29 323 RF Biomarkers for objective assessment and early detection of work related upper extremity musculoskeletal disorders (WRUEMSDs) 10,75 clinico assistenziale Musculoskeletal, Oral and Skin Sciences , RF Untargeted approach in detecting food adulteration and contamination using spectroscopic techniques database and chemometrics 10,75 biomedica Veterinary Food Safety FOSA , RF Origin and evolution of recent vector borne virus incursions in the Mediterranean Basin 10,75 biomedica Veterinary Animal Health ANHE , GR THE RELATIONSHIP BETWEEN BORDERLINE PERSONALITY DISORDER AND BIPOLAR DISORDER: A CLINICAL, MORPHOLOGIAL CEREBRAL AND BIOLOGICAL COMPARISON STUDY 10,75 biomedica Brain Disorders and , RF Pulmonary Rehabilitation and Inflammation Status in COPD 10,75 clinico assistenziale Cardiovascular and , GR ARTT: Androgen receptors as targets for the treatment of estrogen and progestin receptor positive and negative breast cancers 10,75 clinico assistenziale Oncology 2 Clinical , RF Integrated program of experimental and clinical research to improve the outcome of lung transplantation 10,75 biomedica Cardiovascular and , GR Administration of Protein C concentrates in patients with severe sepsis and contraindication to activated protein C. A multicentre randomized placebocontrolled study. 10,75 clinico assistenziale Infectious Diseases and Microbiology 331 RF Expanding the donor pool through the therapeutic applications of carbon monoxide (CO) and biliverdin in transplantation. Evaluation of efficacy in an in vivo porcine model and feasibility of a clinical trial in the donor 10,75 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , RF TRANSLATIONAL APPLICATIONS ENSUING CIRCULATING IMMUNOCOMPLEXES STUDY IN GASTRIC CARCINOMA AND LYMPHOMA FROM ENTIFICATION OF BIOMARKERS TO PRODUCTION OF POTENTIAL THERAPEUTIC COMPOUNDS 10,75 biomedica Biological Chemistry and Macromolecular Biophysics , RF Generation of artificial lymphoid organs to enhance anti tumor immunity. 10,75 biomedica Immunology ,00 Pagina 29 di 244

30 334 RF Characterisation of the Envelope protein sequence of HIV 1 subtype C variants and evaluation of their sensitivity/resistance to neutralisation by sera from HIVinfected individuals: an approach for the development of novel immunogens for a vaccine against 10,75 biomedica AS and Related Research , RF Prevention of work injuries Evaluating the effectiveness of safety interventions carried out by Occupational Health Services of Local Health Authorities in the whole Veneto region (Northeastern Italy) from 2001 to ,75 clinico assistenziale Healthcare Delivery and Methodologies , RF Immuno phenotypic and microrna profiles in breast cancer and adjacent noninvolved tissues as biomarkers of tumor progression 10,75 biomedica Oncology 2 Clinical , RF A multi center phase II randomized study of CustOmized Neoadjuvant ThErapy vs Standard chemotherapy in non small cell lung cancer (NSCLC) patients with resectable stage IIIA(N2) disease (CONTEST trial) 10,84 clinico assistenziale Oncology 2 Clinical , RF Dialogue between "tissue signaling lymphocytes" and keratinocytes in the expression and persistence of psoriatic phenotype: identification of molecular pathways for innovative biologic therapy 10,84 biomedica Immunology , GR TIA pathway implementation to improve clinical management in a second level hospital 10,84 clinico assistenziale Brain Disorders and , RF Teleradiology program for frail patients living at home or in nursing homes 10,88 clinico assistenziale Healthcare Delivery and Methodologies , GR Autoimmunity associated with primary immunodeficiency due to partial V(D)J recombination defects: mechanisms and novel therapeutic approaches 11 biomedica Immunology , RF Impact of HCV natural variants on new anti viral drugs: implementation of a national sequence database of HCV viruses circulating in Italy 11 biomedica Infectious Diseases and Microbiology , GR Study of effects of rapamycin treatment on cortical neurons of a mouse model of Amyotrophic Lateral Sclerosis 11 biomedica Molecular, Cellular, and Developmental Neuroscience ,00 Pagina 30 di 244

31 344 RF Prognostic role of neurophysiological monitoring (continuous video EEG, somatosensory and auditory evoked potentials) in neonatal hypoxic ischemic encephalopathy managed with hypothermia 11 clinico assistenziale Brain Disorders and , GR Effect of SMS based life style intervention in subjects with obesity or moderate cardiovascular risk 11 biomedica Population Sciences and Epidemiology , RF Pathway Dissection In Leukocyte Extravasation: Identification And Validation Of Novel Therapeutic Targets In Nonresolving Inflammatory Processes 11 biomedica Immunology 347 GR Relationship between DNA damage and signaling revealed in mouse models of Ataxia Telangiectasia 11 biomedica Oncology 1 Basic , GR The use of a biodrug, CTLA4 Ig, in the immunometabolic control of experimental multiple sclerosis 11 biomedica Immunology , GR A PROSPECTIVE STUDY TO EVALUATE THE RELATIONSHIP BETWEEN HISTOLOGICAL FEATURES AND VASCULAR RESISTANCES ASSESSED BY MACHINE PERFUSION IN KNEYS FROM OLDER DONORS AND THE PREDICTIVE VALUE OF THESE TWO PARAMETERS ON GRAFT OUTCOMES 11 clinico assistenziale Digestive, Kidney and Urological Systems , GR MECHANISMS OF RESISTANCE TO CHEMOTERAPEUTIC AND ANTI ANGIOGENIC DRUGS AS NOVEL TARGETS FOR PANCREATIC CANCER THERAPY 11 biomedica Oncology 1 Basic , GR PRECLINICAL DETECTION OF ALZHEIMER'S DISEASE BY ADVANCED MRI TECHNIQUES: FUNCTIONAL MRI AND DIFFUSION TENSOR IMAGING 11 clinico assistenziale Brain Disorders and , RF NOVEL AND SELECTIVE ANTI TUMOR STRATEGIES FOR THE TREATMENT OF GLIOMA 11 biomedica Brain Disorders and , GR Detection and characterization of new caliciviruses in swine and development of novel diagnostic tools to assess their circulation in humans 11 biomedica Veterinary Animal Health ANHE , RF Diet induced changes in visceral fat associated inflammation and colon cancer 11 biomedica Immunology , GR A PRECLINICAL PLATFORM TO STUDY THE PATHOGENESIS OF STROKE RELATED FOCAL EPILEPSY 11 biomedica Brain Disorders and ,00 Pagina 31 di 244

32 356 RF Genetic and genomic approaches for the study of sporadic ALS: new animal models 11 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Role of mitochondrial S adenosylmethionine transporter in mitochondrial methylation and metabolism: a new potential target for the study of the maternally inherited deafness 11 biomedica Genes, Genomes and , RF PEPTE RECEPTOR RADIONUCLE THERAPY WITH 177Lu DOTATATE ASSOCIATED WITH METRONOMIC CAPECITABINE IN PATIENTS AFFECTED BY AGGRESSIVE GASTRO ENTERO PANCREATIC NEUROENDOCRINE TUMORS 11 clinico assistenziale Oncology 2 Clinical , RF Analysis of in vivo and in vitro immunogenicity of putative GPI anchored proteins of Babesia for vaccine and diagnostic purposes 11 biomedica Veterinary Animal Health ANHE 360 RF A prospective study on the role played by maternal prenatal stress, in interaction with mother infant relationship and genetics, on later infant bio behavioural development. 11 biomedica Biobehavioral and Behavioral Processes , RF Genomic function of the c Myc oncoprotein 11 biomedica Genes, Genomes and , RF New approaches to early diagnosis of breast cancer based on identification of metabolites in cancer patient breath and biological fluids as candidate biomarkers 11 biomedica Oncology 2 Clinical , RF Prognosis and therapy of melanoma: the potential role of micrornas 11 biomedica Oncology 2 Clinical , GR New strategy for the treatment of schizophrenia and other neurodegenerative diseases: inhibition and allosteric regulation of serine racemase 11 biomedica Biological Chemistry and Macromolecular Biophysics , GR Malformations of cortical development: diagnostic algorithm and straightforward tools to identify and characterize novel disease genes 11 biomedica Genes, Genomes and , RF Innovative approach for the in vivo detection and treatment of Multiple Myeloma 11 biomedica Oncology 2 Clinical ,00 Pagina 32 di 244

33 367 RF Health Technology Assessment (HTA) of HIV rapid testing policy in Italy 11 clinico assistenziale AS and Related Research , GR Development of new highly selective anti LOX 1 receptor molecules to use for the prevention and therapy of reperfusion injury in acute myocardial infarction 11 biomedica Cardiovascular and RF Diffusion of HPV infection and clinical correlates in males 11 biomedica Infectious Diseases and Microbiology RF Purinergic P2X7 Receptor in Amyotrophic Lateral Sclerosis 11 biomedica Brain Disorders and , GR Identification of novel genetic biomarkers of response to treatment in Multiple Sclerosis: a genome wide approach 11 biomedica Genes, Genomes and 372 GR Natural history, genetics and immunopathogenesis of potential celiac disease. 11 biomedica Digestive, Kidney and Urological Systems , RF The impact and biology of HIV associated neurocognitive disorders (HAND) in treated patients with HIV infection achieving systemic virological suppression 11 biomedica AS and Related Research , RF EMERGENCY GERIATRIC EVALUATION UNIT: A MODEL TO IMPROVE EFFECTIVENESS AND QUALITY OF THE MANAGEMENT AND CARE OF THE ELDERLY IN THE EMERGENCY ROOM 11 clinico assistenziale Healthcare Delivery and Methodologies , GR Culture and characterisation of oral mucosal and conjunctival epithelial stem cells for the reconstruction of the ocular surface in patients with bilateral limbal stem cell deficiency 11 biomedica Brain Disorders and , RF Study of the role of Toll like receptors in leukemogenesis 11 biomedica Oncology 1 Basic , RF New therapeutical approach for osteoarthritis: in vitro and in vivo evidences of bone marrow cell transplantation 11 biomedica Musculoskeletal, Oral and Skin Sciences , RF Pathogenesis of Major Psychoses and Dementias: hypothesized points of convergence 11 biomedica Brain Disorders and Pagina 33 di 244

34 379 RF Cell therapy for treatment of restenosis: a preclinical study in rat and pig animal models 11 biomedica Vascular and Hematology , RF Biomaterial funtionalization for orthopaedic and dental use to improve their biofunctionality and osseointegration in healthy and osteopenic bone. 11 biomedica Musculoskeletal, Oral and Skin Sciences , RF Epigenetic abnormalities as novel targets for treatment in chronic myeloproliferative neoplasms. From genome wide methylation analysis to clinical trial. 11 biomedica Oncology 1 Basic , RF Imaging of molecular events during mammary tumorigenesis as a novel approach for the identification of new clinically useful tumour biomarkers. 11 biomedica Oncology 1 Basic , RF Cerebrospinal fluid proteome from Central Nervous System pediatric tumours: patient related pattern 11 clinico assistenziale Oncology 2 Clinical , RF The role of human Erv1 (GFER) and disulphide relay system in mitochondrial diseases 11 biomedica Musculoskeletal, Oral and Skin Sciences , RF Identification of novel mechanisms of the inflammatory response in cystic fibrosis: A window for therapeutical opportunities 11 biomedica Cardiovascular and , RF Upstream pathways and downstream effectors regulating the tumorigenic action of eukaryotic Initiation Factor 6 11 biomedica Oncology 1 Basic , RF Monocytes as novel biomarkers for the evaluation of cystic fibrosis 11 biomedica Cardiovascular and RF Genetic and epigenetic elements in the individual predisposition to lung cancer 11 biomedica Genes, Genomes and , , GR Role of hypoxia induced mir 210 in tissue response to peripheral ischemia 11 biomedica Vascular and Hematology , RF Pathogenesis of Multiple Sclerosis: the role of the vitamin D/vitamin D receptor complex 11 biomedica Genes, Genomes and , RF Study of vitiligo pathogenesis: lipids and signal transduction alterations 11,17 biomedica Musculoskeletal, Oral and Skin Sciences ,00 Pagina 34 di 244

35 392 RF Insight into molecular events involved in the cooperation between bcl 2 and hypoxia in the regulation of tumor progression and angiogenesis 11,17 biomedica Oncology 1 Basic , GR Neural basis of social intelligence: a lesion based multicenter study on stroke patients 11,25 clinico assistenziale Brain Disorders and , GR Differentiation therapy of rhabdomyosarcoma with a cocktail of myomirs 11,25 biomedica Oncology 2 Clinical , GR The ubiquitin editing protein A20 (TNFAIP3) as a peacekeeper in inflammation and immunity: a link between TNFAIP3 deregulation and Multiple Sclerosis 11,25 biomedica Brain Disorders and , GR MITOLESS: genes, mechanisms, and experimental therapy of mtdna depletion syndromes 11,25 biomedica Genes, Genomes and , GR Delivery of adipose tissue derived multipotent adult stem cells as a cell therapy approach for treating Collagen VI related muscular dystrophies 11,25 biomedica Musculoskeletal, Oral and Skin Sciences , RF Longitudinal pattern of Streptococcus pneumoniae nasopharyngeal carriage and antimicrobial susceptibility in healthy children aged <=5 years in the metropolitan area of Milan, Northern Italy. 11,25 clinico assistenziale Infectious Diseases and Microbiology , GR MicroRNAs in chronic myeloproliferative neoplasms: profiling, diagnostic and prognostic relevance and therapeutical perspectives 11,25 biomedica Genes, Genomes and , RF Search for specific micrornas as possible biomarkers for early diagnosis of lymphoma in HBV and/or HCV positive patients 11,25 biomedica Oncology 2 Clinical , GR Human oocytes ultra vitrification by ultra fast cooling at low concentration of cryoprotectants 11,25 biomedica Bioengineering Sciences and Technologies , RF Metabolic markers, MRS detected, to evaluate radiation resistance in cancer (MARE) 11,25 biomedica Oncology 1 Basic , RF Monitoring adaptive responses in chronic hepatitis B virus infection as a tool to optimize antiviral therapy 11,25 biomedica Infectious Diseases and Microbiology Pagina 35 di 244

36 404 RF Nilotinib for steroid refractory chronic graft versus host disease 11,25 biomedica Oncology 2 Clinical , RF EFFECTS OF SELECTIVE INACTIVATION OF THE DYT1 GENE IN STRIATAL CHOLINERGIC NEURONS: PATHOPHYSIOLOGICAL IMPLICATIONS FOR DYT1 DYSTONIA 11,25 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Nanostructured scaffolds for the regeneration of nervous system injuries 11,25 biomedica Bioengineering Sciences and Technologies , RF Development of radio labeled nanodevices decorated with matrix metalloproteinases inhibitors as nanoscopic imaging agents for cancer detection: synthesis, chemical and biological characterization and micro imaging in a mouse model of colorectal cancer 11,25 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Strategies for preservation of the ovarian reserve in cancer therapy and autoimmunity conditions. 11,25 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Dietary restriction and GH/IGF I axis involvement in the mechanisms of differential cellular protection: a strategy to enhance the efficacy of cancer chemotherapy. 11,34 biomedica Oncology 1 Basic , RF A NOVEL DIFFUSION TENSOR MR BASED APPROACH TO EVALUATE STRUCTURAL FEATURES OF BRAIN TUMORS 11,34 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , RF New approaches for cancer therapy based on manipulation of the tumor vascular physiology with chromogranin A and its fragments 11,34 biomedica Oncology 1 Basic , RF Novel bioactive small diameter vascular grafts able to reduce initial thrombosis and to accelerate in vivo endothelialisation 11,34 biomedica Bioengineering Sciences and Technologies , GR Defining cancer stem cell pathogenic mechanisms by modulating developmental transcription factor genes in keratinocytes 11,5 biomedica Oncology 1 Basic , RF Early Environmental Determinants of Child Development and Respiratory Health: a Birth Cohort Study in Central Italy 11,5 clinico assistenziale Population Sciences and Epidemiology Pagina 36 di 244

37 415 GR Development of a neuro anatomical model for assessing and predicting cognitive deficits associated with parietal lesions 11,5 biomedica Biobehavioral and Behavioral Processes , RF In search for biomarkers predicting coronary bypass graft patency: Identification of molecular signatures of inflammation and coagulation. 11,5 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , RF High throughput Exome sequencing analysis of 300 subjects with mental retardation 11,5 biomedica Genes, Genomes and , RF Novel therapeutic strategies for Amyotrophic Lateral Sclerosis: testing the efficacy of cell permeable peptides in preclinical models 11,5 biomedica Brain Disorders and , RF MMP9 mediated role of SCF/Bad patwhay in the progression of atherosclerosis: exploring the possibility to modulate carotid plaque growth 11,5 biomedica Vascular and Hematology , RF Clinical and genetic study of early onset epilepsies of unknown aetiology 11,5 clinico assistenziale Brain Disorders and , RF Probiotic Lactobacillus strains: preclinical study to assess their potential immunomodulatory effect in Myasthenia Gravis and its experimental model 11,5 biomedica Brain Disorders and , RF Identification of genetic and environmental risk factors in migraine: first multicentric Italian Genome Wide Association Study 11,5 biomedica Genes, Genomes and 423 RF Allogeneic hematopoietic stem cell transplantation from HLA matched donors in patients with familial amyotrophic lateral sclerosis 11,5 biomedica Brain Disorders and 424 GR How Corpus Callosum changes in Alzheimer's Disease and in different forms of degenerative dementias 11,5 clinico assistenziale Brain Disorders and , RF Mathematical biophysics models to assess the effects of the dynamical interplay between tumour cells in a solid tumour undergoing a drug based therapy 11,5 biomedica Bioengineering Sciences and Technologies , GR Development of analytical methods to identify treatments with recombinant somatotropin in buffalos 11,5 biomedica Veterinary Food Safety FOSA ,00 Pagina 37 di 244

38 427 GR Parkinson s disease: effects of the aging on progenitor neural cells and bone marrow stromal cells 11,5 biomedica Brain Disorders and , GR Development of a biological profile to predict cognitive decline and dementia in the elderly and to monitor the effects of preventive interventions 11,5 biomedica Population Sciences and Epidemiology , GR Imaging in MR spectroscopy: reconstruction of high spatial resolution metabolic maps 11,5 biomedica Bioengineering Sciences and Technologies , RF DETERMINATION IF LACK OF VARIABILITY IN CARDIAC R R INTERVAL ON EKG PREDICTS THE DEVELOPMENT OF THE CLASSIC MOTOR FEATURES OF PARKINSON S DISEASE. 11,5 clinico assistenziale Brain Disorders and , GR Implication of the transcription factor Yin Yang 1 in B cell non Hodgkin lymphoma development and progression 11,5 biomedica Oncology 1 Basic , GR A Double Blind, Multicenter, Randomized, Placebo controlled Study to Investigate the Impact of Serum Phosphorous Control on Kidney Disease Progression and Mortality in Moderate to Advanced Non dialysis dependent Kidney Dysfunction 11,5 clinico assistenziale Population Sciences and Epidemiology , GR Phase II study of interleukin 2 and zoledronic acid as maintenance therapy in multiple myeloma patients undergoing autografting 11,5 clinico assistenziale Oncology 2 Clinical , GR TAVI versus traditional approaches in treating severe symptomatic aortic stenosis 11,5 clinico assistenziale Healthcare Delivery and Methodologies , GR Respiratory gated PET/CT technique and 18F FAZA for the evaluation of hypoxia in non small cell lung cancer (NSCLC) 11,5 clinico assistenziale Oncology 2 Clinical 436 RF INFLUENCE OF GENETIC AND GENOMIC BACKGROUND ON RESISTANCE TO ANTIVIRAL THERAPY, PREDISPOSITION TO DEVELOP HEPATOCELLULAR CARCINOMA AND SEVERITY OF RECURRENCE AFTER LIVER TRANSPLANT IN CHRONIC HEPATITIS C PATIENTS. 11,5 biomedica Genes, Genomes and , RF Analysis of current dynamics of tuberculosis in a low incidence country 11,5 clinico assistenziale Population Sciences and Epidemiology ,00 Pagina 38 di 244

39 438 RF and Pathogenesis of Steroid Resistant Nephrotic Syndrome 11,5 biomedica Genes, Genomes and , RF Utilization of Regional Health Service databases for evaluating epidemiology, short and medium term outcome, and process indexes in patients hospitalized for heart failure. 11,5 clinico assistenziale Healthcare Delivery and Methodologies , RF Development of new vaccines for animal salmonellosis 11,5 biomedica Veterinary Animal Health ANHE , RF Developing Therapeutic Strategies Based on Intra Bone Transplant of Hematopoietic Stem Cells 11,5 biomedica Vascular and Hematology , RF Identification and validation of biological outcome predictors in mantle cell lymphoma 11,5 clinico assistenziale Oncology 2 Clinical , GR New antimicrobial agents targeting antibiotic resistance mechanisms and novel or underexploited targets 11,5 biomedica Infectious Diseases and Microbiology , RF Early diagnosis of pending failures of total hip arthroplasty with hard to hard bearings 11,5 clinico assistenziale Musculoskeletal, Oral and Skin Sciences , GR Genetic elements linking inflammatory responsiveness to lung cancer susceptibility 11,5 biomedica Genes, Genomes and , RF Novel molecular targets against drug resistant bacterial and protozan infections 11,5 biomedica Biological Chemistry and Macromolecular Biophysics , RF Thrombolysis with r TPA for wake up stroke patients within 3 hours of symptoms awareness: a multi centre randomized open label controlled study 11,5 clinico assistenziale Brain Disorders and , RF OXATIVE STRESS, AGEING, AND RESPIRATORY DISEASES. A multi centre epidemiological and genetic study on the general adult and elderly population in Italy. 11,5 clinico assistenziale Healthcare Delivery and Methodologies , RF MOBI KS Italy Brain cancer risk from exposure to radiofrequency fields in childhood and adolescence: a multicentric international study 11,67 clinico assistenziale Population Sciences and Epidemiology ,00 Pagina 39 di 244

40 450 RF Identification of New Early Biomarkers in Kidney Malignancies 11,67 biomedica Digestive, Kidney and Urological Systems , GR Human Well Being: a Twin Study on the Relation between Optimal Psychological and Biological Functioning 11,75 biomedica Biobehavioral and Behavioral Processes , RF Role of innate immunity in human herpes simplex virus (HSV) 1 infection and its related neuropathologies. 11,75 biomedica Immunology 453 GR Combining microarrays, computational biology and molecular immunology: innovative diagnosis and vaccine discovery for Pneumococcal diseases 11,75 biomedica Bioengineering Sciences and Technologies , RF DEVELOPMENT OF NOVEL BETA GLUCAN BASED, GLYCOCONJUGATE VACCINES AND ANTI BETA GLUCAN ANTIBODIES FOR UNIVERSAL PROTECTION AGAINST FUNGAL PATHOGENS 11,75 biomedica Immunology , GR Genomewide evaluation of genetic factors associated with progressive nonalcoholic steatohepatitis by an Italian research network 11,75 biomedica Genes, Genomes and 456 GR A zebrafish based integrated biosensor for molecular diagnosis, multi organ analysis and drug screening in Alagille syndrome 11,75 biomedica Genes, Genomes and , GR Hemodynamic Neurotechnology for Stroke Rehabilitation 11,75 clinico assistenziale Brain Disorders and , GR Human Cytomegalovirus, Adenovirus and Epstein Barr virus infection and cellular immune response: factors associated to prevention of congenital infection and correlates of protection in transplanted patients. 11,75 biomedica Immunology , GR Role of upar in the epidermal stem cell compartment, skin carcinogenesis and hair follicle regeneration. 11,75 biomedica Musculoskeletal, Oral and Skin Sciences 460 GR The capacity to consent to treatment in Amyotrophic Lateral Sclerosis 11,75 clinico assistenziale Healthcare Delivery and Methodologies , RF Risk evaluation associated with Legionella water system contamination: data interpretation from Viability PCR, Real time PCR and culture. 11,75 clinico assistenziale Infectious Diseases and Microbiology ,00 Pagina 40 di 244

41 462 GR Assessment of neuropsychological and neurobiological effects in adult life of prenatal and early postnatal stress experiences 11,75 biomedica Biobehavioral and Behavioral Processes , GR Molecular Changes in Endocrine Resistant Breast Cancer: Relationship between Hormone Receptor and Growth Factor Receptor Family 11,75 biomedica Oncology 2 Clinical , GR Mindfulness Based Cognitive Therapy for patients with Amyotrophic Lateral Sclerosis: a Randomized Controlled Trial 11,75 clinico assistenziale Biobehavioral and Behavioral Processes , RF A Comprehensive clinical approach to Rare Tumours: From genetics to targeted clinical approach. 11,75 biomedica Oncology 2 Clinical , GR Identification of candidate disease genes in familial Amyotrophic Lateral Sclerosis using a targeted exon capture and resequencing approach 11,75 biomedica Brain Disorders and , GR Exosomes as diagnostic markers for prion diseases: exploiting the infectivity vehicle 11,75 biomedica Infectious Diseases and Microbiology , RF Function of Rac1 and Rac3 GTPases in the development of cortical and hippocampal interneurons. 11,75 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Myeloid derived suppressor cells, purinergic signalling, and tumor immunity 11,75 biomedica Immunology RF CD99 bridges molecular therapy to differentiation of bone sarcoma 11,75 biomedica Oncology 1 Basic RF Treatment of neuromuscular diseases by inhibition of dystroglycan proteolysis 11,75 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Randomized clinical trial comparing the safety and efficacy of the use of fixeddose combination efavirenz/tenofovir/emtricitabine (Atripla ) on alternate days versus continuous treatment 11,75 clinico assistenziale AS and Related Research , RF CDKL5 gene: clinical phenotype and effects of mutations on development of the central nervous system in view of future therapeutic approaches 11,75 biomedica Brain Disorders and ,00 Pagina 41 di 244

42 474 RF Characterization of the tick Anaplasma interface: Development of vaccines for the integrated control of tick infestations and the transmission of tick borne pathogens, A. marginale and A. phagocytophilum. 11,84 biomedica Veterinary Animal Health ANHE 475 RF Indicators of diabetes and cardiovascular risk and therapy efficacy in subjects with early impairment of glucose metabolism. 11,84 biomedica Genes, Genomes and , RF Multicenter randomized study on the efficacy of immunosuppression in patients with virus negative inflammatory cardiomyopathy 11,84 clinico assistenziale Cardiovascular and , RF Familial breast cancer: low risk alleles, genetic modifiers and screen for variants in associated genes/loci. 11,84 biomedica Oncology 1 Basic , GR Epidemiology and Genomics of taste, food preferences and Healthy Eating in three Italian Isolated Populations 11,84 biomedica Genes, Genomes and , RF GABAergic dysfunction in the development and etiology of childhood and adult intractable epilepsies 12 biomedica Brain Disorders and , GR Inhibition of adrenal beta arrestin 1 signaling pathway as a new therapeutic target to counteract the adverse effects of heart failure related hyperaldosteronism. 12 biomedica Cardiovascular and , GR The local control of thyroid hormone action in skin tumorigenesis and in the treatment of basal cell carcinomas 12 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Melanocortin 1 receptor variants in skin carcinogenesis: a pooled analysis 12 biomedica Oncology 1 Basic , GR Construction of microfluidic device to detect protein trace present in ocular liquid to monitor chronic brain diseases 12 biomedica Bioengineering Sciences and Technologies , RF ITALIAN OBSERVATIONAL STUDY ON VEGETATIVE STATE 12 clinico assistenziale Healthcare Delivery and Methodologies , RF Non human primate model for HIV/AS: a platform to generate and evaluate therapeutic antibodies against structural and non structural proteins of HIV biomedica AS and Related Research ,00 Pagina 42 di 244

43 486 RF Cerebrospinal Fluid Ceruloplasmin oxidation as Parkinson s Disease Biomarker: role in pathological mechanisms 12 biomedica Brain Disorders and , RF Health outcomes at school age of a population based cohort of very preterm infants: the ACTION III project 12 clinico assistenziale Population Sciences and Epidemiology , RF The interplay between innate and adaptive immunity in the initial steps of chronic inflammatory diseases: psoriasis as a model 12 biomedica Immunology , RF Biomolecular characterization of methylation and new histone deacetylase inhibitors: implications for cancers and their treatment. 12 biomedica Oncology 1 Basic , GR A look into the exciting network of Myospryn 12 biomedica Cardiovascular and , GR VALATION OF MPI AS PROGNOSTIC INDEX FOR ELDERLY CANCER PATIENTS; EVALUATION OF COMORBITY, POLIPHARMACOLOGY AND POTENTIAL DRUG INTERACTIONS; PAIN ASSESSMENT AND TREATMENT AND CORRELATION WITH QUALITY OF LIFE IN ELDERLY (AGE > 70 YEARS) PATIENTS WITH CA 12 clinico assistenziale Oncology 2 Clinical , RF FETAL HEMOGLOBIN INDUCTION IN BETA THALASSEMIA: ROLE OF BCL11A AND MYB IN MEDIATING THE EFFECT OF KIT LIGAND AND THALOME, RESPECTIVELY 12 biomedica Vascular and Hematology , GR Pharmacogenetics of analgesic drugs: towards a personalized medicine for treatment of neuropathic pain 12 biomedica Genes, Genomes and , RF Mechanism of interaction between osteoclast and T cells in periprosthetic osteolysis: new perspectives for an early diagnosis 12 biomedica Musculoskeletal, Oral and Skin Sciences , RF Novel cellular and molecular mechanisms in the pathogenesis of chronic obstructive pulmonary disease 12 biomedica Cardiovascular and , GR Identification of myogenic precursor cells forming new myofibers in regenerating skeletal muscle for the cell therapy of the muscular dystrophy. 12 biomedica Musculoskeletal, Oral and Skin Sciences ,00 Pagina 43 di 244

44 497 GR Assessment of the safety of antipsychotic drugs in elderly with dementia: an international, population based study using healthcare databases 12 clinico assistenziale Brain Disorders and , GR ROLE OF THE ACTIN REGULATORY PROTEINS, EPS8 AND IRSp53, IN THE PROGRESSION OF ORAL SQUAMOUS CELL CARCINOMA. 12 biomedica Oncology 1 Basic , GR Defining Estrogen Receptor beta selective agonists as candidate molecules for the medical therapy of cholangiocarcinoma 12 biomedica Oncology 1 Basic , RF MULTISCIPLINARY AND COMPREHENSIVE KNOWLEDGE ON BONE DISORDERS IN HIV INFECTION: CLINICAL EPEMIOLOGICAL FACTORS, RISK SCORES, INTEGRATED DIAGNOSTIC IMAGING AND BASIC SCIENCES. SKELETON STUDY 12 clinico assistenziale AS and Related Research , RF Analysis of peripheral biomarkers to evaluate the efficacy of acetylcholinesterase inhibitor and antiglutamatergic drugs in Alzheimer's disease 12 biomedica Brain Disorders and 502 RF PROTECTIVE AND DANGEROUS IMMUNE RESPONSES IN HIV INFECTED CHILDREN 12 biomedica AS and Related Research , RF GENETIC TESTING BY ARRAY BASED COMPARATIVE GENOMIC HYBRISATION IN AUTISM SPECTRUM DISORDERS 12 biomedica Genes, Genomes and , RF HMGB1 in the treatment of the failing heart 12 biomedica Cardiovascular and 505 GR Pain free Microneedle based Integrated Glycemic Holter for Metabolic Control of Patients with Diabetes Mellitus (MICROHOLTER) 12 biomedica Bioengineering Sciences and Technologies 506 RF Comparative Effectiveness of Treatments for Degenerative Spine Disease 12 clinico assistenziale Musculoskeletal, Oral and Skin Sciences , RF Effectiveness and cost effectiveness of new organizational integrated home care models 12 clinico assistenziale Healthcare Delivery and Methodologies , RF Resistin and cardiovascular risk in type 2 diabetes 12 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences ,00 Pagina 44 di 244

45 GR A new tool for individual risk assessment of prostate cancer patients 12 biomedica Oncology 1 Basic RF Novel molecular players in melanoma growth and progression. 12 biomedica Oncology 1 Basic RF Detection of diarrhoea causing protozoa by multiplex real time PCR assays 12 biomedica Infectious Diseases and Microbiology , , , GR Role of fibroblasts in intestinal inflammation: implications for celiac disease therapy and diagnosis 12 biomedica Digestive, Kidney and Urological Systems , GR Development of innovative adipose tissue mesenchymal stem cell based strategies for bone tissue regeneration using pharmacological agents 12 biomedica Cell Biology , RF Muteins of human NGF with therapeutic potential for Alzheimer s Disease: expression, production and pharmacological studies 12 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Evaluation of an innovative approach for motor rehabilitation after stroke by manipulating central pathways: a physical and pharmacological intervention 12 biomedica Brain Disorders and , GR Role of leukocyte telomere length and CD34+ hematopoietic precursor telomerase activity in the pathogenesis of cellular senescence in diabetic nephropathy. 12 biomedica Digestive, Kidney and Urological Systems , GR Genetic Variation Of Dopamine D2 Receptor And Response to Antipsychotics In Patients With Behavioural And Psychological Symptoms Of Dementia 12 biomedica Biobehavioral and Behavioral Processes , RF Development of a new vaccine against tuberculosis 12 biomedica Immunology , RF ARTEMIS (Augmented Realism in Teleconsulting and Education in Minimally Invasive Surgery) 12 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Tumorgraft models for the discovery of the molecular culprits of rectal cancer and the design of patient specific therapeutic protocols 12 biomedica Oncology 1 Basic 521 RF TRANSMISSION OF CREUTZFELDT JAKOB DISEASE BY BLOOD: EPEMIOLOGICAL AND EXPERIMENTAL TRANSMISSION STUDIES 12 biomedica Population Sciences and Epidemiology ,00 Pagina 45 di 244

46 522 RF Development of new experimental models for mental retardation and autism by studying Shank3 and IL1RAPL1 function in synapse formation using ips technology 12 biomedica Brain Disorders and , GR Proteomic and lipidomic investigations in Multiple Sclerosis: research of molecular biomarkers 12 biomedica Biological Chemistry and Macromolecular Biophysics , RF TRAIL producing UC MSCs as cell based therapy for multiple myeloma: a preclinical study 12 biomedica Oncology 1 Basic , RF Assessment and control of selected priority contaminants intake through the characterisation of rural and indoor environments ENVI FOOD 12 biomedica Veterinary Food Safety FOSA , GR Preventive and therapeutic effects of zinc oxide and silver particles on bacteria involved in caries pathogenesis 12 biomedica Bioengineering Sciences and Technologies , RF Lineage control of muscle derived adult stem cells by mirna mediated regulation of the composition of the SWI/SNF chromatin remodeling complex 12 biomedica Musculoskeletal, Oral and Skin Sciences , GR Role of the transcription factor Nfix in muscle regeneration and muscular dystrophies 12 biomedica Musculoskeletal, Oral and Skin Sciences 0, RF The effect of blindness and visual impairment on neurocognitive mechanisms: clinical and rehabilitative implications 12 biomedica Biobehavioral and Behavioral Processes , GR Evaluation of two Adapted Physical Activity (APA) training programs on cardiopulmonary parameters, inflammatory cytokines response, nutrients intake and body composition in subjects affected by chronic obstructive pulmonary disease (COPD). 12 clinico assistenziale Biology of Development and Aging , GR BBB and inflammation in epilepsy: novel targets for pharmacological intervention 12 biomedica Brain Disorders and , RF Genetic tauopathies: the involvement of tau protein in chromosome stability as a cause of neurodegeneration 12 biomedica Brain Disorders and , RF Lost HuB: cell cycle deregulation and suppression of neuronal differentiation by a tumor suppressor candidate in gliomas 12 biomedica Oncology 1 Basic ,00 Pagina 46 di 244

47 534 RF Evaluation of bacteriocins safety and efficacy as a strategy to control Campylobacter in poultry chain 12 biomedica Veterinary Food Safety FOSA , RF Modulation of the NAD salvage pathway as a novel pharmacological approach for spinal cord injury 12 biomedica Brain Disorders and , RF Enhancing cell proliferation in favor of regenerative medicine 12 biomedica Musculoskeletal, Oral and Skin Sciences , RF BONE TISSUE REGENERATION FOR THE TREATMENT OF CONGENITAL PSEUDARTHROSIS OF THE TIBIA 12 biomedica Musculoskeletal, Oral and Skin Sciences , RF Nano structured coatings enhance biomaterials performance for joint reconstruction 12 biomedica Bioengineering Sciences and Technologies , GR A Cellular Model to Predict Disease Evolution and Response to Treatment in Patients with Systemic Mastocytosis 12 biomedica Vascular and Hematology , RF THE UP REGULATION OF BACE1 AS PARADIGM OF THE PHYSIOLOGIC AND PATHOLOGIC EFFECTS OF BETA AMYLO biomedica Brain Disorders and , RF Immunoproteomic, host parasite interaction and molecular epidemiology of Echinococcus granulosus 12 biomedica Infectious Diseases and Microbiology , RF Post transcriptional control of gene expression and cancer. 12 biomedica Genes, Genomes and , RF LONG TERM PROGNOSIS OF EPILEPSY. A multi center retrospective survey of prognostic patterns in newly diagnosed patients 12 clinico assistenziale Population Sciences and Epidemiology , RF Histone deacetylase inhibitors as anti inflammatory drugs: dissecting molecular mechanisms and targets 12 biomedica Immunology 545 RF EGFR expression identifies distinct tumor initiating cells in human glioblastoma multiforme: selection and functional validation of an EGFR associated TIC specific molecular signature with potential predictive value. 12 biomedica Oncology 1 Basic ,00 Pagina 47 di 244

48 546 RF Innovative and integrated approaches to understand the genetic bases of hearing loss 12 biomedica Genes, Genomes and , RF Fibrin resistance to lysis in pulmonary hypertension 12 biomedica Cardiovascular and , RF Identification of genes for rare neurological traits by homozygosity mapping and exome sequencing 12 biomedica Genes, Genomes and , RF UNDERSTANDING PODOCYTE SIGNALING TO IMPROVE DIAGNOSIS AND TREATMENT OF FOCAL SEGMENTAL GLOMERULOSCLEROSIS 12 biomedica Digestive, Kidney and Urological Systems , RF Discovery of a new class of drugs aimed at reducing HIV latent reservoirs: HIV 1 Tat mimicking compounds 12 biomedica AS and Related Research , RF Therapeutic potential based on neural plasticity induced by the Rho GTPase activator CNF1: the case of Rett syndrome and neurophatic pain 12 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Relationships between receptor tranducer selectivity and tolerance to opioid ligands 12 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Regulation of Wnt signaling for bone regeneration in localized bone defects 12 biomedica Musculoskeletal, Oral and Skin Sciences RF Molecular crosstalk between cancer and aging: The p53 p66shc signalling pathway. 12 biomedica Biology of Development and Aging , , RF Identification of beta cell specific aptamers as in vivo imaging tools in diabetes mellitus 12 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , RF IMmunity, Inflammation and Carotid ATherosclerosis: The IMICAT study 12 biomedica Vascular and Hematology , GR THE PROTEIN C PATHWAY IS A NOVEL MEDIATOR IN INTESTINAL HOMEOSTASIS: therapeutic implications for inflammatory bowel disease treatment 12 biomedica Vascular and Hematology Pagina 48 di 244

49 RF MicroRNAs role in aging dependent impairment of angiogenesis 12 biomedica Biology of Development and Aging RF Regulatory T cells at tumor site: phenotype diversity and functional implication 12 biomedica Oncology 2 Clinical RF Spinocerebellar ataxia type 28, from molecular hypothesis to preclinical treatment 12,17 biomedica Brain Disorders and , GR Validation of autoimmunity to PDGF receptor as a pathogenic mechanism in scleroderma 12,17 biomedica Musculoskeletal, Oral and Skin Sciences , GR ReShape: Evaluation of possible determinants for early and late cardiac remodeling after mitral valve repair with annuloplasty using new computational tools. 12,17 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Evaluation of advanced technologies to improve sensitivity and throughput of multiplex immunoassays for diagnosis of animal infectious diseases 12,17 biomedica Veterinary Animal Health ANHE , GR The role of natural selection in shaping the genetic predisposition to chronic inflammatory diseases: multiple sclerosis and inflammatory bowel disease 12,17 biomedica Genes, Genomes and , RF Bone disorders in chronic liver diseases: identification of cellular and molecular mechanisms 12,17 biomedica Musculoskeletal, Oral and Skin Sciences , RF Magnetic Cardiac Targeting of Thermomagnetoliposomes entrapping L T3 to reverse ischemic myocardial remodeling in pigs. 12,2 biomedica Cardiovascular and , GR Facing the Pandemic Influenza virus threat: development of RNA interferencebased innovative therapeutic approaches, targeting the anti interferon NS 1 viral gene product. 12,25 biomedica Infectious Diseases and Microbiology , GR TOWARD A THERAPEUTIC APPROACH IN CONGENITAL CENTRAL HYPOVENTILATION SYNDROME (CCHS): IN VITRO ENTIFICATION OF DRUGGABLE PHOX2B TARGETS AND SCREENING OF EFFECTIVE PHARMACEUTICAL AGENTS 12,25 biomedica Molecular, Cellular, and Developmental Neuroscience ,00 Pagina 49 di 244

50 569 GR Alternative splicing as a tool to identify novel angiogenesis modulators for therapeutic purposes 12,25 biomedica Oncology 1 Basic 570 GR Epigenetic Risk Assesment (ERA) of Assisted Reproductive Technologies (ART) 12,25 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences 571 GR Microsomal Prostaglandin E synthase type 1 as a therapeutical target in controlling tumor progression and angiogenesis promoted by EGFR/K Ras 12,25 biomedica Oncology 2 Clinical , RF New methods for sentinel lymph node mapping and intraoperative analysis by One Step Nucleic Acid Amplification (OSNA) in breast cancer patients: identification of new biological parameters correlated with sentinel and nonsentinel lymph node metastases 12,25 biomedica Oncology 2 Clinical , RF Primary progressive aphasia. Development and validation of a standardized diagnostic procedure in Italian patients 12,25 biomedica Brain Disorders and , RF Levosimendan to reduce mortality in high risk cardiac surgery patients. A multicentre randomized controlled trial 12,25 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering 575 GR ROLE OF CHIKUNGUNYA VIRUS GENETIC VARIABILITY IN PATHOGENETIC MECHANISMS 12,25 biomedica Infectious Diseases and Microbiology , RF Study on Neuroprotective Role of Conjuctivally Applied Nerve Growth Factor in Childhood Optic Gliomas 12,25 clinico assistenziale Brain Disorders and , GR Implementation of functional Magnetic Resonance Imaging techniques on the first Italian 7 Tesla Magnet 12,25 biomedica Emerging Technologies and Training in Neurosciences , RF Exome sequencing in diagnosis of rare hereditary anemias 12,25 biomedica Genes, Genomes and , RF Molecular basis of sporadic and familial Amyotrophic Lateral Sclerosis in Italy: a morbidity map of disease genes 12,25 biomedica Brain Disorders and ,00 Pagina 50 di 244

51 580 RF F FDG PET as a predictor of response to cognitive rehabilitation for mild cognitive impairment 12,25 clinico assistenziale Brain Disorders and , RF From micro GIST to macro GIST: dissection of the molecular pathways that underlie the malignant evolution of GIST 12,34 biomedica Oncology 1 Basic , RF Clinical and molecular investigation of HPV associated anal cancer precursors in immunocompetent and immunocompromised hosts. 12,34 biomedica Oncology 1 Basic , GR Endocytosis, Notch signaling and tumor suppression: From flies to human cancer 12,34 biomedica Cell Biology , GR In vivo non invasive optical diagnosis of skin lesions 12,34 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Study of autophagy dysregulation in Parkinson's Disease for the identification of new diagnostic markers using bio engineered neural cells obtained from the chemical reprogramming of easily accessible dermal fibroblasts 12,34 biomedica Brain Disorders and , RF MULTIMODAL CLINICAL NEUROPHYSIOLOGICAL AND NEUROIMAGING APPROACH TO DISORDERS OF CONSCIOUSNESS IN THE REHABILITATION PHASE 12,5 biomedica Brain Disorders and , RF Implementation and optimization of T cell therapy for EBV related tumors 12,5 clinico assistenziale Oncology 2 Clinical , RF In vitro and in vivo studies on a new blood component: platelet gel from cord blood 12,5 clinico assistenziale Healthcare Delivery and Methodologies , RF Atherosclerosis and osteoporosis: identification of common pathogenetic factors. 12,5 clinico assistenziale Vascular and Hematology , RF Epigenetic markers of melanoma progression 12,5 biomedica Oncology 1 Basic , RF Microparticles released from reactive microglia: a potential biomarker for multiple sclerosis and neurodegenerative diseases 12,5 biomedica Brain Disorders and ,00 Pagina 51 di 244

52 592 RF Skin lipidoma: an innovative tool to investigate individual vulnerability and repair capacity of photodamaged skin 12,5 biomedica Musculoskeletal, Oral and Skin Sciences , RF Nutrient(Zinc) gene interaction in old patients affected by Chronic Obstructive Pulmonary Disease (COPD) and muscle weakness//hypotrophy (Sarcopenia). 12,5 biomedica Genes, Genomes and 594 RF Development of a microarray based diagnostic system for the detection of major bacterial agents of acute respiratory tract infections and antibiotic resistance genes at point of care 12,5 biomedica Infectious Diseases and Microbiology , RF Nano self assembled niosomal aggregates: an innovative multi drug delivery system for pulmonary tuberculosis 12,5 biomedica Bioengineering Sciences and Technologies , GR A LONGITUDINAL STUDY OF NEURAL PLASTICITY IN CHILDREN WITH AUTISM SPECTRUM DISORDERS 12,5 clinico assistenziale Brain Disorders and , GR CORD BLOOD SERUM EYE DROPS IN THE TREATMENT OF OCULAR SURFACE DISEASES IN GVHD PATIENTS 12,5 biomedica Interdisciplinary Molecular Sciences and Training , GR Non invasive induction of long term synaptic plasticity in the human cerebellum: a new strategy for the rehabilitation of cerebellar disorders. 12,5 clinico assistenziale Brain Disorders and , RF Metabotropic glutamate receptors and endocannabinoids: functional interactions and physiopathological role in cerebral ischemia 12,5 biomedica Brain Disorders and , RF Combination of new biomarkers to predict mortality in elderly patients affected by myocardial infarction 12,5 biomedica Genes, Genomes and , GR ALBRIGHT HEREDITARY OSTEODYSTROPHY AND PSEUDOHYPOPARATHYROISM: INVESTIGATION ON THE DISRUPTED SIGNALLING UNDERLYING ITS PATHOGENESIS AND ENTIFICATION OF A NOVEL CLINICAL, BIOCHEMICAL AND MOLECULAR CLASSIFICATION 12,5 clinico assistenziale Genes, Genomes and , RF STUDY OF THE MICROENVIRONMENT IN PATIENTS WITH MONOCLONAL GAMMOPATHY: ENTIFICATION OF NEW MOLECULAR TARGETS 12,5 biomedica Oncology 1 Basic ,00 Pagina 52 di 244

53 603 GR p140cap as a tumour suppressor gene in breast cancer: prognostic value and therapeutic approaches 12,5 biomedica Oncology 1 Basic , RF Adrenal tumors: from molecular studies to clinical application 12,5 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Pharmacogenetics in Parkinson s disease treatment: circulating lymphocytes as a novel tool to predict drug efficacy and tolerability 12,5 biomedica Genes, Genomes and , GR Development of innovative immunotherapeutic strategies against oligomeric beta amyloid isoforms by intracellular antibody technology 12,5 biomedica Brain Disorders and , RF A NEW POTENTIAL THERAPEUTIC TOOL IN FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY (FSHD): EXPLORING IN VIVO AND IN VITRO SKELETAL MUSCLE DIFFERENTIATION OF AUTOLOGOUS FSHD MESOANGIOBLASTS 12,5 biomedica Musculoskeletal, Oral and Skin Sciences , GR Melanoma shapes immune cells & stroma microenvironmental components through exosome driven transfer of functional molecules 12,5 biomedica Immunology , GR Mesenchymal Stem Cells Therapy for the treatment of intervertebral disc degeneration: from bench and animal model to bedside 12,5 biomedica Musculoskeletal, Oral and Skin Sciences 610 RF Resting state activity and its gabaergic modulation of stimulus induced activity in depression: A translational investigation 12,5 biomedica Biobehavioral and Behavioral Processes , GR Role of Mediterranean Diet and vitamin D in prevention of cognitive decline in subjects with cognitive impairment 12,5 clinico assistenziale Risk, Prevention and Health Behavior , GR Role of autophagy in the development and prognosis of CNS tumors 12,5 biomedica Cell Biology , RF Unraveling the immunological mechanisms and molecular correlates of IFN alpha plus Ribavirin treatment efficacy for improving disease management in HCVinfected patients 12,5 biomedica Immunology ,00 Pagina 53 di 244

54 614 GR Identification and characterization of "cancer stem cells/tumor initiating cells" in chronic lymphocytic leukemia 12,5 biomedica Oncology 1 Basic , RF Endocrine evaluation of adult patiens with beta thalassemia with particular focus on GH secretion. Effects of rhgh treatment in thalassemic patients with GH deficiency. 12,5 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Revealing Chronic Lymphocytic Leukemia intra clonal complexity: a tool for the conceivement of novel highly specific therapeutic approaches and the identification of a Leukemic Stem Cell 12,5 biomedica Oncology 1 Basic , GR An analysis of genetic and environmental factors affecting language development in typically developing children and children with Specific Language Impairment 12,5 biomedica Genes, Genomes and , RF Striatal synaptic plasticity in experimental models of Parkinson s disease: molecular mechanisms and therapeutics implications 12,5 biomedica Brain Disorders and , RF Improving characterization of anti leukemia activity mediated by NK cells derived from patients and haploidentical donors of hematopoietic stem cells: molecular interactions, identification of optimal donors, immune evasion mechanisms. 12,5 biomedica Oncology 2 Clinical , RF DEFINITION OF AN APPROPRIATE TIME WINDOW IN THE PERI NATAL PHASE TO PREVENT ALLERGEN SENSITIZATION: PRECLINICAL STUDY IN PREGNANT AND NEWBORN MICE 12,5 biomedica Immunology , RF Genetic and biological aspects of familial/sporadic TDP43 proteinopathies 12,5 biomedica Genes, Genomes and , RF ENTIFICATION OF NOVEL THERAPEUTIC AGENTS FOR IMPAIRED SKIN WOUND HEALING IN DIABETES 12,5 biomedica Cardiovascular and , RF Understanding the WHIM syndrome: molecular analysis of CXCR4 functions in leukocyte trafficking and activation 12,5 biomedica Immunology , RF Prevalence and impact on total mortality of chronic kidney disease in patients with type 2 diabetes in Apulia; a paradigm for a region based study whose data may be specifically implemented in the management of chronic metabolic and vascular diseases in 12,5 clinico assistenziale Population Sciences and Epidemiology ,00 Pagina 54 di 244

55 625 RF Development and validation of a novel platform of multifunctional fusion proteins for in vivo imaging and therapy of glioblastoma 12,5 biomedica Molecular, Cellular, and Developmental Neuroscience 626 RF Integrated high throughput approaches to ascertain novel mechanisms of RAS signaling dysregulation in human disease 12,5 biomedica Genes, Genomes and , RF The Identification of a Proteomic Signature and Development of new Prognostic Markers and Therapeutic Targets in Chronic Lymphocytic Leukemia 12,5 biomedica Oncology 1 Basic , RF Identification of key functional mediators in innate immune cells from subjects naturally controlling HIV infection in the absence of antiretroviral therapy. 12,5 biomedica Immunology , GR Use of Icg loaded erythrocytes for choroidal angiography and retinal laser photocoagulation. 12,5 biomedica Bioengineering Sciences and Technologies , RF Clinical and biological features of multiple myeloma patients in first relapse following frontline therapy with new drugs 12,5 biomedica Oncology 2 Clinical , GR Motor wave propagation in the human spinal cord: normal and pathological gait 12,67 biomedica Integrative, Functional, and Cognitive Neuroscience , GR From GWAS to high resolution mapping and functional analyses: gaining mechanistic insights with clinical implications into susceptibility to nevus development, malignant melanoma and pancreatic cancer 12,67 biomedica Oncology 1 Basic , RF Role of REST, linked to TSC2 and beta catenin, in the transformation of medullo and neuroblastomas. 12,67 biomedica Cell Biology , RF Amplification of the RARA gene in a sub population of patients with HER2 positive breast carcinoma is associated with sensitivity to retinoic acid and derivatives: from the bench to the bedside and the other way around. 12,67 biomedica Oncology 1 Basic , RF PHD fingers in human diseases: structural and functional studies of SP140 PHD finger 12,67 biomedica Biological Chemistry and Macromolecular Biophysics ,00 Pagina 55 di 244

56 636 RF Novel molecular markers of thyroid neoplasms 12,75 biomedica Oncology 1 Basic , RF HPV as primary screening test in cervical cancer prevention: from DNA to mrna? A randomised controlled trial nested in a double testing study with long term follow up. 12,75 clinico assistenziale Oncology 2 Clinical 638 GR ASSESSMENT OF INDIVUAL GENETIC PROFILE IN HEALTHY YOUNG INDIVUALS WITH AND WITHOUT FAMILY HISTORY OF PROSTATE CANCER: IMPLICATIONS FOR INDIVUALIZED PROSTATE CANCER SCREENING PROGRAMS 12,75 clinico assistenziale Genes, Genomes and , GR Transcriptional silencing by zinc finger technology to treat gain of function mutations 12,75 biomedica Genes, Genomes and , GR PHARMACOKINETIC, PHARMACODYNAMIC AND PHARMACOGENOMIC ASSESSMENTS APPLIED TO THE OPTIMIZATION OF ANTI LEUKEMIC THERAPY FOR PEDIATRIC ACUTE LYMPHOBLASTIC LEUKEMIA 12,75 biomedica Oncology 2 Clinical , GR Ovarian reserve in women and their reproductive competence 12,75 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Diagnosis and treatment of inflammatory arthropathies in the Regione Emilia Romagna: a prospective population based study 12,75 clinico assistenziale Healthcare Delivery and Methodologies , GR Hypersexuality and pathological gambling associated to Parkinson's disea se: development of preclinical animal models, study of their causes and neurochemical mechanisms and clinical evaluation of their features and progression 12,75 biomedica Brain Disorders and , GR A forecasting model for drug utilization and expenditure integrating a Cellular Automata model with the Budget Impact Analysis approach. 12,75 clinico assistenziale Healthcare Delivery and Methodologies , RF Early combined ropinirole and rasagiline therapy in newly diagnosed patients with Parkinson s disease. A multicenter prospective randomized follow up study including delayed start design of rasagiline 12,75 clinico assistenziale Brain Disorders and ,00 Pagina 56 di 244

57 646 RF Targeting of ALK kinase activity in neuroblastoma 12,75 biomedica Oncology 2 Clinical , RF The relationship of psychopathological and immunological changes to coronary heart disease: prospective observational study of subjects experienced April 6th 2009 L'Aquila earthquake 12,75 biomedica Integrative, Functional, and Cognitive Neuroscience , RF Metabolomic profiling of adult patients with newly diagnosed acute myeloid leukemia (AML) undergoing intensive treatment 12,75 biomedica Biological Chemistry and Macromolecular Biophysics , GR Phenotypic characterization of parkinsonian syndromes associated with glucosecerebrosidase mutations 12,75 clinico assistenziale Brain Disorders and , GR Development of a new analytical method for combined determination of the toxins most commonly found in Italian seafood 12,75 biomedica Interdisciplinary Molecular Sciences and Training , RF SPATIAL TEMPORAL INTERACTIONS IN THE BRAIN: CLINICAL/REHABILITATIVE IMPLICATIONS 12,75 clinico assistenziale Brain Disorders and , GR Diagnosis of cardiovascular disease in the low HDL people: a nanotechnological approach in the identification of blood cell patognomonic features. 12,75 biomedica Cardiovascular and , GR Role of micrornas 143 and 145 in cardiovascular physiology and disease: from bench to bedside 12,75 biomedica Vascular and Hematology , GR ORGANIZATION OF A REGIONAL REFERENCE LABORATORY FOR THE (STANDARDIZATION OF) MOLECULAR MONITORING OF PHILADELPHIA POSITIVE LEUKEMIAS 12,75 clinico assistenziale Vascular and Hematology , GR HERITABLE DISORDERS OF CONNECTIVE TISSUE: EARLY DETECTION OF AORTIC ANEURYSMS AND PREVENTION OF DISSECTION 12,75 clinico assistenziale Cardiovascular and , RF The role of hypoxia in regulating micrornas and target genes in cancer biology: identification of new therapeutic targets 12,75 biomedica Oncology 1 Basic ,00 Pagina 57 di 244

58 657 GR A in vivo Study of the Interaction between Lymphocytes, and Antigen Presenting Cells in the Pathophysiology of chronic GVHD following Allogeneic Hematopoietic Stem Cell Transplantation 12,75 clinico assistenziale Vascular and Hematology , GR Prevention of medical device related infections by innovative anti microbial biofilm polymers 12,75 biomedica Infectious Diseases and Microbiology 659 GR GORMITA (Generator Of Response Markers Impacting Targeted Agents): a comprehensive approach for the identification of molecular predictors of response to targeted treatments in soft tissue sarcomas 12,75 biomedica Oncology 1 Basic , RF Non Integrating Lentiviral Vectors for AS Vaccine 12,75 biomedica AS and Related Research , RF Mesenchymal stem cell derived microvesicles for the treatment of nephropathic cystinosis and other monogenic lysosomal disorders 12,75 biomedica Genes, Genomes and , RF Early identification of newborns at high risk of brain injury through a validated biomarkers profile and specific neuro imaging patterns. A follow up study of clinical and neurodevelopmental outcome in a large cohort study. 12,75 clinico assistenziale Brain Disorders and , GR Age related hearing impairment: an innovative, multidisciplinary and International approach to identify genetic and environmental risk factors based on high throughput technologies 12,75 biomedica Genes, Genomes and , RF STUDY OF THE WILD TYPE SOD1 AGGREGATION IN LYMPHOBLASTS OF SPORADIC ALS PATIENTS TO OPEN NEW PERSPECTIVES IN THE PATHOLOGICAL MECHANISMS 12,75 biomedica Molecular, Cellular, and Developmental Neuroscience , GR A new rehabilitation approach for Alzheimer's Disease 12,75 biomedica Brain Disorders and , GR Determination of kinase inhibitor resistance mechanisms and develoment of novel inhibitor compounds in anaplastic large cell lymphoma and melanoma 12,75 biomedica Oncology 2 Clinical , GR Profile of inflammatory mediators in patients with psoriasis, and their association with comorbidities. 12,8 biomedica Musculoskeletal, Oral and Skin Sciences ,00 Pagina 58 di 244

59 668 RF Functional approaches for identification of novel targets in thyroid carcinogenesis 12,84 biomedica Oncology 1 Basic , RF Development and exploitation of a platform able to produce antibody based reagents. From monoclonal murine antibody to completely human reagent using protein engineering to raise new potent diagnostic and therapeutic tools in oncology 12,84 biomedica Immunology , RF Developing of specific, sensitive and non invasive diagnostic tests on all saliva for heavy drinker subjects 13 biomedica Risk, Prevention and Health Behavior , GR Clinical and biological activity of curcumin in patients with psoriasis vulgaris 13 clinico assistenziale Musculoskeletal, Oral and Skin Sciences , GR The activation of GPR35 by Kynurenic acid in the schizophrenia associated deficit of glutamatergic transmission 13 biomedica Brain Disorders and , RF Tailored Beta catenin mutational approach in extra abdominal sporadic desmoid tumor patients 13 clinico assistenziale Oncology 2 Clinical , GR Human models for identifying biomarkers of cutaneous beta HPV infection and the definition of their oncogenic implications 13 biomedica Infectious Diseases and Microbiology , RF Calcium/Calmodulin dependent kinases: novel links between metabolic stress and inflammatory response 13 biomedica Immunology , GR Gastrointestinal neuropathies induced by neurotropic viruses: innate cellular mechanisms and cell based repair in neurodegeneration 13 biomedica Digestive, Kidney and Urological Systems , GR Analysis of RNA processing defects in amyotrophic lateral sclerosis 13 biomedica Genes, Genomes and , GR Identification of a Bcr Abl/Hausp network that inactivates the tumor suppressor PTEN in Chronic Myeloid Leukemia 13 biomedica Oncology 1 Basic , RF Erasing fear in post traumatic stress disorder: monitoring neuronal connectivity in hippocampal cortical networks during reconsolidation or extinction of remote aversive memories 13 clinico assistenziale Brain Disorders and ,00 Pagina 59 di 244

60 680 GR TMEM127, the new tumor suppressor gene predisposing to pheochromocytoma 13 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Acinetobacter baumannii colonization/infection in ICU patients: two sides of the coin? 13 clinico assistenziale Infectious Diseases and Microbiology , GR Identification and functional analysis of mutations in FMR1 and FMRP interacting genes CYFIP1 and BC200 in a large cohort of patients with idiopathic mental retardation and/or autism. 13 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Role of human CYP3A4 and CYP3A5 genetic polymorphisms on the pharmacokinetics of Protease Inhibitor Lopinavir/Ritonavir in HIV 1 infected subjects 13 clinico assistenziale AS and Related Research , GR Periodontal disease as emergent systemic pathology: development of a new clinical unit for patients global health care 13 clinico assistenziale Healthcare Delivery and Methodologies , RF Targeting tumours with competitive proteins and bi functional antibodies to interfere with receptor tyrosine kinase/ beta1 integrin cross talk: validation and preclinical studies 13 biomedica Oncology 1 Basic , GR Cytokines and antibodies in the treatment of disseminated neuroblastoma: a preclinical study 13 biomedica Oncology 2 Clinical , GR Development and characterization of a rat model of alpha synuclein induced neuronal degeneration: toward a better understanding and treatment of Parkinson s disease 13 biomedica Brain Disorders and , GR MicroRNA regulation by mutant p53 oncoprotein in human cancer. 13 biomedica Oncology 1 Basic , RF The microenvironment of classical Hodgkin Lymphoma: the role of MSC in promoting tumor growth, the formation of an immunosuppressive microenvironment, the induction of drug resistance. 13 biomedica Oncology 1 Basic ,00 Pagina 60 di 244

61 690 GR Therapeutic targeting of the initial steps of the metastatic cascade through RNAibased identification and pre clinical validation of components of the "proteoglycan system" 13 biomedica Cell Biology , GR The morphological and microstructural MRI correlates of motor, cognitive and neurobehavioral impairment in Parkinson disease 13 clinico assistenziale Biobehavioral and Behavioral Processes , GR Angiogenic and Immunogenic Aspects of Coronary Transplant Arteriosclerosis 13 biomedica Vascular and Hematology , RF A multicentric study to standardize a new informatic tool to assess cognitive and behavioral functions in acute stroke 13 clinico assistenziale Integrative, Functional, and Cognitive Neuroscience , GR The Rai adaptor protein in Th17 cell differentiation, effector function and chemotaxis and in the pathogenesis of multiple sclerosis 13 biomedica Immunology , GR THE ROLE OF MACROPHAGES IN PRIMARY BILIARY CIRRHOSIS 13 biomedica Immunology , RF A Systems Biology approach to understand Melanoma in the context of the immune response 13 biomedica Immunology , GR Understanding integrins' role in cancer: energetic and molecular insights into ligand recognition process 13 biomedica Biological Chemistry and Macromolecular Biophysics , RF Molecular mechanisms linking hypertension and Alzheimer's disease: role of Receptor for Advanced Glycation End products (RAGE). 13 biomedica Brain Disorders and , GR Study of epigenetic program in heart failure to identify of novel potential therapeutic targets 13 biomedica Cardiovascular and , RF Genetic regulation of inflammation mediated activation of haemostasis 13 biomedica Genes, Genomes and , RF Role of mesenchymal stromal cells in lymphoma mediated immunosuppression: a novel target for the treatment. 13 biomedica Immunology ,00 Pagina 61 di 244

62 702 RF innovative Device for transabdominal relevation of fetal oxygen saturation (ADRIANA) 13 biomedica Bioengineering Sciences and Technologies , RF Characterization of epsins function in endocytosis, epidermal homeostasis and cancer 13 biomedica Oncology 1 Basic , RF Can Mesenchymal Stem Cells used as therapeutic agents induce the formation of tumors in the host? 13 biomedica Musculoskeletal, Oral and Skin Sciences , RF Discovery and clinical translation of a factor that rebuilds immunity after bone marrow transplant 13 biomedica Immunology , GR Dystrophic cardiomyopathy as an investigational model for novel therapeutic approaches 13 biomedica Cardiovascular and , RF NO NSA for the treatment of cancer 13 biomedica Oncology 1 Basic , RF Mechanisms of reactivation of the FMR1 gene and analysis of pathways involved in the pathogenesis of fragile X syndrome: towards a drug based therapy. 13 biomedica Genes, Genomes and , RF Search of novel therapies for latent tuberculosis 13 biomedica Infectious Diseases and Microbiology 710 RF Unlocking tumor immune recognition through self HLA E molecules 13 biomedica Immunology , GR Neoadjuvant targeted agents followed by surgery in squamous cell carcinoma of head and neck: detection of promising agents through identification of molecular and imaging parameters to predict treatment activity and/or resistance 13 clinico assistenziale Oncology 2 Clinical , RF Tailored screening for breast cancer in premenopausal women. A translational, randomized, population based trial. 13 clinico assistenziale Oncology 2 Clinical 713 GR Systems Biology of von Hippel Lindau syndrome 13 biomedica Biological Chemistry and Macromolecular Biophysics ,00 Pagina 62 di 244

63 714 RF Biological and clinical implications of two mirna clusters potentially associated with lack of clinical response to conventional chemotherapy in advanced stage ovarian carcinomas 13 biomedica Oncology 2 Clinical , RF Regulation of histone deacetylase 1 and 2 13 biomedica Cell Biology , RF Evaluation in elderly patients with urogenital cancer (prostate, kidney, bladder and penis) of the geriatric care needs and pathways after initial treatment. 13 clinico assistenziale Oncology 2 Clinical , RF Hepatocyte growth factor as a regulator of indoleamine 2,3 dioxygenase 1 (O1) expression in cancer 13 biomedica Immunology , GR Longitudinal observational 36 months prospective study aimed at exploring diagnostic and prognostic salivary proteomic biomarkers for primary Sjögren' s syndrome (pss) 13,17 clinico assistenziale Musculoskeletal, Oral and Skin Sciences , RF FROM CONFOCAL ENDOSCOPY TO TARGETED ENDOSCOPY FOR EARLY DETECTION AND TREATMENT OF ESOPHAGEAL AND COLONIC NEOPLASTIC LESIONS. 13,17 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , GR SLEEP WAKE DISTURBANCES IN INTERNAL MEDICINE: THE LIVER MODEL 13,17 clinico assistenziale Digestive, Kidney and Urological Systems , RF Novel therapeutic strategy combining an extracellular matrix mediated and cell surface based platform for the simultaneous targeting of neovascular elements and tumor cells. 13,17 biomedica Oncology 2 Clinical , RF Magnetic resonance imaging with hyperpolarized 13C pyruvate for innovative cardiac diagnostic imaging 13,17 biomedica Cardiovascular and , RF Cardiovascular complication in Familial HDL Deficiency: new diagnostic tools from circulating cell biology 13,25 biomedica Cardiovascular and , RF Development of scfvs against the HPV16 E6, E7, L1 and L2 proteins for diagnostic, prognostic and therapeutic applications 13,25 biomedica Oncology 2 Clinical , RF Genetic study for the diagnosis and treatment of patients with Porphyria. 13,25 clinico assistenziale Genes, Genomes and Pagina 63 di 244

64 726 GR Quality of life, cognitive abilities and costs of transcatheter aortic valve implantation and surgical aortic valve replacement 13,25 clinico assistenziale Cardiovascular and 727 RF Biomarker driven development of 3rd generation anti angiogenic cancer therapies 13,25 clinico assistenziale Oncology 2 Clinical , GR Therapeutical approaches for diabetes due to the proteotoxic effect of misfolded insulin and beta cellular ER stress 13,25 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR From genes to function: statistical and experimental investigation of neurodegenerative mechanisms in Multiple Sclerosis 13,25 biomedica Genes, Genomes and , GR Activation of A3 adenosine receptor by Cl IB MECA in a mouse model of melanoma. 13,25 biomedica Immunology , RF Predictive factors in endocrine unresponsive breast cancer patients 13,25 clinico assistenziale Oncology 2 Clinical , RF Preclinical and clinical studies using a new human radiolabeled recombinant monoclonal antibody fragment (scfv anti CEA) by PET imaging in the localization of gastric cancers. 13,25 biomedica Oncology 2 Clinical 733 RF Molecular events involved in progression from hepatitis C virus (HCV) chronic infection to hepatocellular carcinoma: mirnome and proteome analysis in experimental and clinical settings 13,25 biomedica Infectious Diseases and Microbiology , GR THE FATE OF MELANOPSIN RETINAL GANGLION CELLS AND PHOTOENTRAINMENT OF CIRCADIAN RHYTHMS IN NEURODEGENERATION 13,25 biomedica Brain Disorders and , RF INNOVATIVE STRATEGY ADDRESSED TO TERRITORIAL AND HOSPITAL INTERACTION AT REGIONAL LEVEL FOR IMPROVED MANAGEMENT OF ADVANCED LIVER DISEASE 13,25 clinico assistenziale Digestive, Kidney and Urological Systems , RF Phenotypic and genetic characterization of ALS: a step towards developing effective therapies 13,25 biomedica Brain Disorders and ,00 Pagina 64 di 244

65 737 RF Neurobiology of Fragile X Syndrome: a biochemical and electrophysiological study on developmental pre and post synaptic mechanisms. 13,25 biomedica Brain Disorders and , RF Novel functions for D aspartate in the mammalian brain and its potential involvement in schizophrenia 13,25 biomedica Brain Disorders and , RF Understanding the biological continuum between Amyotrophic lateral sclerosis (ALS) and Fronto temporal dementia (FTD): a step towards a more efficient assistance model for the affected patients 13,25 clinico assistenziale Brain Disorders and , RF Hypoxia in neuroblastoma tumors: from the biology to the identification of novel predictors of outcome 13,25 biomedica Oncology 2 Clinical , GR Amniotic fluid derived mesenchymal stromal cells as potential cellular component for bone repair 13,3 biomedica Musculoskeletal, Oral and Skin Sciences , RF Role of pro angiogenic factors in leukemogenesis and evaluation of the effectiveness of their targeting as anti tumor therapy 13,34 biomedica Oncology 1 Basic , GR Bisphosphonates and Bone s Material Composition 13,34 clinico assistenziale Musculoskeletal, Oral and Skin Sciences 744 RF ACTIVITY OF METFORMIN ON CELL PROLIFERATION IN PATIENTS WITH EARLY BREAST CANCER 13,34 clinico assistenziale Oncology 2 Clinical , RF Innovative adhesives for the treatment of retinal detachment: development and biocompatibility assessment. 13,34 biomedica Bioengineering Sciences and Technologies , GR EPIGENETIC ROLE OF NITRIC OXE IN THE SENESCENCE AND AGING 13,5 biomedica Biology of Development and Aging , RF Genomic and transcriptional profiling of primary cutaneous B cell lymphoma for the improvement of cancer molecular diagnostic 13,5 biomedica Oncology 2 Clinical , GR Therapy based on A2A receptor antagonism in combination with mesenchymal stem cell transplantation in an animal model of stroke 13,5 biomedica Brain Disorders and ,00 Pagina 65 di 244

66 749 GR MET Inhibitors and MHC Unrestricted Adoptive Immunotherapy: Potentials and Synergisms in a Non Small Cell Lung Cancer Preclinical Model. 13,5 biomedica Oncology 1 Basic , GR Calcium dependent cell cell adhesion molecule dysfunctions associated to mutations of protocadherin 19 (PCDH19) gene (Xq22) in epilepsy. Molecular screening and identification of the causative role of PCDH19 gene in a spectrum of epilepsy phenotypes and g 13,5 biomedica Genes, Genomes and , GR New therapeutic approach to Autosomal Dominant Osteopetrosis (ADO) 13,5 biomedica Genes, Genomes and RF MEDications in the ELderly NETwork Acute Care (MEDELNET AC) 13,5 clinico assistenziale Healthcare Delivery and Methodologies , , RF Evolution of H1N1 pandemic influenza viruses and its impact on influenza prevention and control 13,5 biomedica Infectious Diseases and Microbiology , RF Detection of early markers of Bronchiolitis obliterans syndrome (BOS) by proteomic Broncho Alveolar Lavage fluid analysis with SELDI TOF 13,5 biomedica Cardiovascular and , GR Innovative Technologies in Mental Retardation (ITER) 13,5 biomedica Genes, Genomes and , GR Leptin and obesity: cellular bases of both cardiovascular and cancer risk. 13,5 biomedica Vascular and Hematology , GR A novel transgenic swine model of amyotrophic lateral sclerosis (ALS) 13,5 biomedica Brain Disorders and RF Clinical impact of ultra high field MRI in neurodegenerative diseases diagnosis 13,5 clinico assistenziale Brain Disorders and , GR Metabolic state and natural regulatory T cells: cellular and molecular basis for a novel immune intervention in multiple sclerosis 13,5 biomedica Immunology 760 GR Folic acid assumption in late pregnancy and its interaction with parental and fetal genes in childhood asthma development 13,5 biomedica Population Sciences and Epidemiology ,00 Pagina 66 di 244

67 761 RF THE PATHOPHYSIOLOGICAL SUBSTRATES OF RARE DISEASES PRESENTING WITH CORTICAL HYPEREXCITABILITY AND MYOCLONUS: IMPLEMENTATION OF AN INNOVATIVE FUNCTIONAL APPROACH CAPABLE TO ADVISE THE TREATMENT CHOICE 13,5 biomedica Brain Disorders and , GR EVALUATION OF CARDIOVASCULAR RISK IN HIV POSITIVE PATIENTS UNDER HAART 13,5 clinico assistenziale AS and Related Research , RF A systems biology framework for multiple sclerosis 13,5 biomedica Brain Disorders and , GR Mesenchymal progenitor cells as biomarkers in idiopathic pulmonary fibrosis: a prospective study. 13,5 clinico assistenziale Cardiovascular and , GR The IL 7/IL 7 receptor axis as a common, novel target pathway in autoimmunity and cancer 13,5 biomedica Immunology , GR Characterization of Tertiary Lymphoid Structures in Colorectal Cancer and their clinical relevance 13,5 biomedica Digestive, Kidney and Urological Systems , RF Effects of overweight/obesity and weight loss on metabolic factors associated with increased cancer risk and DNA damage in monozygotic twin pairs discordant for body weight. 13,5 biomedica Oncology 2 Clinical , GR A novel pharmacological approach for the management of spinal cord injury: regulation of NAD pathway 13,5 biomedica Brain Disorders and , GR Study of the Causal Relationship between Intestinal Permeability, Microbial Translocation and T Lymphocyte Hyperactivation in HIV Infected Patients with Poor Immunological Response in Course of Suppressive HAART 13,5 clinico assistenziale AS and Related Research , RF Functional studies of deregulated micrornas in Sezary Syndrome 13,5 biomedica Oncology 1 Basic , GR HYPERHOMOCYSTEINEMIA AND NEUROLOGICAL DISORDERS: EFFECTS ON METHYLATION STATUS AND THERAPEUTICAL PERSPECTIVES 13,5 biomedica Brain Disorders and , GR Systems analysis of mitotic transitions 13,5 biomedica Cell Biology ,00 Pagina 67 di 244

68 773 RF The hidden androgen deficiency in young men. A role as predictor of metabolic syndrome, sexual dysfunction and cardiovascular disease. 13,5 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF RTKs target therapy: toward a prevention of drug resistance 13,5 biomedica Oncology 1 Basic , GR Targeting the ERBB 3 receptor: chimerization and humanization of a murine anti ERBB 3 antibody. 13,5 biomedica Oncology 2 Clinical , RF Metabolomic Profiling of Heart Failure 13,5 biomedica Cardiovascular and , GR MicroRNA signature in colorectal carcinoma: correlation with mutational status of signaling pathways 13,5 biomedica Oncology 2 Clinical , RF REGULATION OF TUMOR DORMANCY BY HETEROTYPIC CELL CELL INTERACTIONS: DISSECTING THE MOLECULAR PATHWAYS DOWNSTREAM OF NOTCH FOR THERAPEUTIC PURPOSES 13,5 biomedica Oncology 1 Basic , RF New models for in vivo and in vitro analysis of carbon nanotubes: an approach for the evaluation of occupational and environmental risk 13,5 biomedica Risk, Prevention and Health Behavior , RF Characterization of intestinal mucosal B cells and isolation of HIV neutralizing monoclonal antibodies 13,5 biomedica AS and Related Research 781 GR ADAM10: from neurodevelopment to neurodegeneration 13,5 biomedica Brain Disorders and , RF Allogeneic stem cell transplantation in hematological malignancies: conditioning with total lymphoid irradiation and thymoglobulin to reduce complications and increase anti tumor effects 13,5 clinico assistenziale Immunology , RF Therapeutics that target EMT in chemoresistant ovarian cancer: emerging role of endothelin A receptor 13,5 biomedica Oncology 1 Basic , RF RESTORING CELL ECM INTERACTION TO RESCUE MUSCLE AND NERVE DEGENERATION IN CONGENITAL MUSCULAR DYSTROPHY 13,5 biomedica Musculoskeletal, Oral and Skin Sciences ,00 Pagina 68 di 244

69 785 RF CARDIOTOXICITY OF ANTICANCER DRUGS AND CHEMOPREVENTIVE APPROACHES 13,5 biomedica Cardiovascular and , RF Development of a stem cell approach for the treatment of TARDP and sporadic Amyotrophic Lateral Sclerosis (ALS stem) 13,5 biomedica Brain Disorders and , RF Cancer Stem Cells and Tumor Associated Fibroblasts in Breast cancer: search for new targeted therapy 13,5 biomedica Oncology 1 Basic , RF Epigenetics of skin repair 13,5 biomedica Musculoskeletal, Oral and Skin Sciences , RF Outpatient Day Service (ODS): a technological integrated innovative health care modality for the secondary prevention in subjects with diabetes mellitus 13,5 clinico assistenziale Healthcare Delivery and Methodologies 790 RF Role of the long pentraxin PTX3 in the biology of lymphatic vessels 13,5 biomedica Cell Biology 791 GR Improvement of feed quality and safety by using functional agents and novel detection system of toxic agents for the attainment of safe and high quality food of animal origin 13,6 biomedica Veterinary Food Safety FOSA , RF An in vitro ad in vivo imaging approach to myelin dysfunction and reconstruction after stroke: role of GPR17, a new player in the specification of stem like neural cells 13,67 biomedica Brain Disorders and , RF Electrophysiological investigation of substantia nigra pars reticulata neurons on the functional effects of high frequency stimulation in the subthalamic nucleus: implications for the Deep Brain Stimulation therapy in Parkinson s disease 13,67 biomedica Brain Disorders and , RF Impact of neurological aging and cognitive impairment on hospitalization and mortality in an Italian elderly general population cohort 13,67 clinico assistenziale Population Sciences and Epidemiology , RF An innovative assay development for minimal residual disease detection in adult patients with acute myeloid leukemia based on Surface Enhanced Raman Spectroscopy 13,67 biomedica Bioengineering Sciences and Technologies ,00 Pagina 69 di 244

70 796 RF NEW INSIGHTS ABOUT BONE METASTATIC NICHE OF HUMAN BREAST CANCER: HEPATOCYTE GROWTH FACTOR/MET SYSTEM ORCHESTRATES THE CROSS TALK METASTASIS/MICROENVIRONMENT AND REGULATES GENE EXPRESSION THROUGH betacatenin/wnt PATHWAY 13,67 biomedica Oncology 1 Basic , RF New insight into thyroid epithelial carcinogenesis: role of oncogene induced senescence 13,67 biomedica Oncology 1 Basic , RF Clinical implications and emotional impact of electrocardiographic and genetic screening for the risk of sudden death in the young: the case of the long QT syndrome 13,67 clinico assistenziale Cardiovascular and , GR Multifunctional coated gold nanoparticles as contrast agents for multimodal imaging in neurodegenerative diseases 13,75 biomedica Brain Disorders and , RF Tumor micro environment as a determinant of outcome to anti EGFR and anti VEGF antibodies in advanced colorectal cancer: a comprehensive analysis 13,75 biomedica Oncology 2 Clinical , RF Identification of regulatory network of myeloid derived suppressor cells by integrating gene expression and microrna expression data. 13,75 biomedica Genes, Genomes and , GR Human Immunoagents for the Therapy of ErbB2 positive cancer patients ineligible to Herceptin treatment 13,75 biomedica Oncology 2 Clinical , RF Randomized phase III trial (OBELICS study) and biomarkers evaluation to optimize the schedule of bevacizumab in combination with chemotherapy in colorectal cancer 13,75 clinico assistenziale Oncology 2 Clinical , RF Radiotherapy as an immunological booster in patients with metastatic melanoma or renal cell carcinoma treated with High dose Interleukin 2: evaluation of biomarkers of immunologic and therapeutic response 13,75 clinico assistenziale Oncology 2 Clinical , GR Experimental models of Alzheimer's disease: development of new therapies based on neural plasticity induced by the Rho GTPases' activator CNF1 13,75 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Antiplatelet therapy tailored by platelet function and pharmacogenetic profile: towards an appropriate use of the new antiplatelet agents 13,75 clinico assistenziale Vascular and Hematology ,00 Pagina 70 di 244

71 807 GR Pharmacogenomic Approach to Personalize and Optimize the Available Drugtherapy for Alzheimer's Disease 13,75 biomedica Genes, Genomes and , GR A new gene for inherited thrombocytopenias: clinical, pathogenetic and pharmacological studies 13,75 biomedica Vascular and Hematology , RF Assessment of different behaviors of non adherence to antiretroviral therapy as predictors of viro immunological and clinical outcome of HIV infection during the last HAART era. 13,75 clinico assistenziale AS and Related Research , RF Peritoneal Mesothelioma: Optimize Outcomes by the Integration of new Prognostic Factors and Potential Therapeutic Targets in a Individualized Treatment based on Molecular Characterization and Chemosensitivity Profile on Primary Cultures. 13,75 clinico assistenziale Oncology 2 Clinical , GR Predictivity for MPN of screening for JAK2 V617F and TET2 mutations in asymptomatic patients with splanchnic thrombosis and usefulness in clinical management and counselling. 13,75 clinico assistenziale Vascular and Hematology , RF Molecular profiles in Male Breast Cancer (MBC) 13,75 biomedica Oncology 1 Basic , GR New immunotherapeutic strategies in pancreatic cancer: pre clinical validation of DNA vaccination with alpha enolase. 13,75 biomedica Oncology 2 Clinical , RF Mechanism based biomarkers in oncology therapy: Evaluation of biochemical and cellular markers as surrogate endpoints for predicting response to neoadjuvant anti EGFR therapy with cetuximab in head and neck cancer patients 13,75 biomedica Oncology 2 Clinical , RF Unraveling neurobiology of social anhedonia as a core dimension of Deficit Schizophrenia 13,75 biomedica Brain Disorders and 816 RF Methods for investments/disinvestments and distribution of health technologies in Italian Regions MDIR 13,75 clinico assistenziale Healthcare Delivery and Methodologies 817 RF Involvement of ALK receptor as critical oncogene and tractable target for pediatric rhabdomyosarcoma. 13,75 biomedica Oncology 2 Clinical ,00 Pagina 71 di 244

72 818 GR FoxO3A meets the mitochondrial genome: may the ultimate newcomer smooth the way toward mitochondrial medicine? 13,84 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Narcolepsy with cataplexy: a model disease for the study of metabolic syndrome determinants 13,84 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences 0, GR Three dimensional (3D) rendering of left ventricular wall structure (viable myocardium, scar, fat) based on Magnetic Resonance or Multi Detector Computed Tomography cardiac imaging as anatomic substrate for electroanatomic mapping and radiofrequency ablat 13,84 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , GR ROLE OF MEMBRANE LIP MICRODOMAINS, RAFTS AND CAVEOLAE, IN THE SIGNALLING OF GROWTH FACTOR RECEPTOR INVOLVED IN THYRO CANCER 13,84 biomedica Cell Biology , RF Neuronal nicotinic acetylcholine receptors as target to enhance inhibitory neurotransmission in temporal lobe epilepsy. 13,84 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Early deprogramming to prevent long term metabolic consequences of intrauterine growth retardation. A nutritional and hormonal approach. 13,84 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF TRANSFORMING GROWTH FACTOR BETA 1 IN THE PATHOPHYSIOLOGY OF HUNTINGTON DISEASE 13,84 biomedica Brain Disorders and , RF The role of autophagy in modulating tumor cell response to targeted agents in relapsed/refractory Hodgkin lymphoma (HL) 13,84 biomedica Oncology 1 Basic , RF Continuity of care for persons with HIV/AS through home and hospice care: a multicentric study to identify barriers to access in the late HAART era 14 clinico assistenziale Healthcare Delivery and Methodologies , RF CONGESTIVE HEART FAILURE IN INTERNAL MEDICINE SETTING: DIFFERENCE BY GENDER IN QUALITY OF LIFE, PREDICTION OF SURVIVAL AND HOSPITALIZATION 14 clinico assistenziale Cardiovascular and ,00 Pagina 72 di 244

73 828 GR Study of progression of clinical and neuroimaging features in early stage parkinsonism: The role of Diffusion weighted Imaging and FDG PET in predicting diagnosis of atypical parkinsonian syndromes 14 clinico assistenziale Brain Disorders and , RF INTENSIVE ADJUVANT CHEMOTHERAPY REGIMEN 14 clinico assistenziale Oncology 2 Clinical , RF Impact of atherosclerosis and hemodynamic markers detected by ultrasound on the outcome of patients with mild degree of carotid stenosis. 14 clinico assistenziale Risk, Prevention and Health Behavior , RF Mechanisms of cardiomyocyte dysfunction in Fabry disease and susceptibility to long term enzyme replacement therapy 14 clinico assistenziale Cardiovascular and , GR AUTOPHAGY A NOVEL POTENTIAL TARGET IN DUCHENNE MUSCULAR DYSTROPHY: ENTIFICATION OF THE PATHWAYS AND NEW PHARMACOLOGICAL STRATEGIES 14 biomedica Musculoskeletal, Oral and Skin Sciences , GR The role for the GnRH receptor in urinary bladder function 14 biomedica Digestive, Kidney and Urological Systems , RF Studying and targeting host parasite membrane dynamics in malaria parasite blood development 14 biomedica Infectious Diseases and Microbiology 835 RF Analysis of the molecular lesions involved in the development of rhabdomyosarcoma in a murine model. New targets for immunoprevention and therapy 14 biomedica Oncology 1 Basic , GR Development of new therapies for L DOPA induced dyskinesia: role of striatal D1R/D3R heterodimeric complex 14 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Validation and application of a biomolecular method for Escherichia coli O157, Salmonella spp. and Listeria monocytogenes examination in raw ovine milk. 14 biomedica Veterinary Food Safety FOSA , GR Tobacco Control: Econometric Analysis and Public Health Implications 14 clinico assistenziale Risk, Prevention and Health Behavior , GR Klotho as a regulator of cardiovascular disease progression in patients with chronic kidney disease. 14 biomedica Cardiovascular and ,00 Pagina 73 di 244

74 840 GR Role of the glycoprotein Dickkopf 3 in the development of cerebral ischemia and ischemic neuronal death 14 biomedica Brain Disorders and , RF Prevalence and risk factors of genital Chlamydia trachomatis infection among sexually active young women (14 25 years), in Italy 14 clinico assistenziale Population Sciences and Epidemiology , GR Surgical resection associated with hyperthermic intraperitoneal chemotherapy in the treatment of peritoneal component of gastric and colo rectal cancers 14 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , RF MiRNA in diagnosis and experimental therapy of pleural malignant mesothelioma. 14 biomedica Oncology 2 Clinical , RF Self performed bandaging in the maintenance phase of breast cancer related lymphedema : advantages of patient's self management 14 clinico assistenziale Risk, Prevention and Health Behavior , RF GENERATION AND IMPLEMENTATION OF A SHARED SYSTEM OF MONITORING, WARNING AND RESPONSE TO ACUTE CLINICAL EVENTS IN PATIENTS HOSPITALIZED IN INTERNAL MEDICINE UNITS 14 clinico assistenziale Healthcare Delivery and Methodologies , GR Focus on Myotonic Dystrophy pathogenesis and MBNL1 proteins: expression, signalling and modulation in DM1 mice models 14 biomedica Genes, Genomes and , GR THE LOW SALT COMMUNITY. A strategy testing and feasibility trial of salt reduction at the population level 14 clinico assistenziale Healthcare Delivery and Methodologies , RF USE OF 2PROPSA FOR THE DETECTION OF PROSTATE CANCER IN PATIENTS WHO ARE CANDATES FOR A PROSTATE BIOPSY 14 clinico assistenziale Digestive, Kidney and Urological Systems , GR Arrhythmogenic Right Ventricular Cardiomyopathy: in vivo experimental models for investigating the molecular pathogenesis and identifying new targets for therapy. 14 biomedica Cardiovascular and , GR Extracellular adenosine triphosphate (eatp) as a pharmacological target in inflammatory muscle myopathies and in muscular dystrophies 14 biomedica Immunology , RF Identification and monitoring of gene mutations in peripheral blood and urine as a diagnostic tool for patients with solid tumors 14 clinico assistenziale Oncology 2 Clinical ,00 Pagina 74 di 244

75 852 RF Combined Phosphodiesterase Inhibitor statin therapy in rat and mouse models of Huntington s disease 14 biomedica Brain Disorders and , GR Th17 responses in Cystic Fibrosis: paving the way for novel anti inflammatory strategies and immunogenetic screening 14 biomedica Cardiovascular and , RF THE METABOLIC SYNDROME IN BREAST CANCER SURVIVORS: FROM CLINICAL EPEMIOLOGY TO MOLECULAR INVESTIGATION 14 biomedica Oncology 2 Clinical , RF Breast Stem Cells and Chemioresistence:Epigenetic Studies 14 biomedica Oncology 1 Basic , RF AMP DEPENDENT KINASE/MAMMALIAN TARGET OF RAPAMYCIN COMPLEX1 SIGNALING IN T CELL ACUTE LYMPHOBLASTIC LEUKEMIA: IMPLICATIONS FOR TARGETED THERAPY 14 biomedica Oncology 1 Basic , RF Safety and Appropriateness of Growth Hormone therapy in Italy 14 clinico assistenziale Population Sciences and Epidemiology , RF New genomic disorders: identification, phenotypic outline and clinical management 14 clinico assistenziale Genes, Genomes and , GR Assessment of fetal exposure to alcohol, drugs of abuse and tobacco by biomarkers detection in neonatal meconium 14 clinico assistenziale Biobehavioral and Behavioral Processes , RF Candida vaginitis and coinfections with Chlamydia trachomatis and Human Papillomavirus: impact on pathogenesis, diagnosis prevention and therapy of these diseases 14 biomedica Infectious Diseases and Microbiology , GR Anti cancer blockers of ErbB2 induce oxidative stress and myocardial dysfunction, countered by PDE5 inhibition, and by enhancement of myocytes Ca2+ cycling and myofilaments Ca2+ sensitivity. 14 biomedica Cardiovascular and , RF Adolescents and young adults cancers: the burden in Italy 14 clinico assistenziale Population Sciences and Epidemiology ,00 Pagina 75 di 244

76 863 RF The Therapeutics Effects of Sport Activity on Disabled People Brain Functions: Neuro Plastic Processes Revealed by the Combination of Electrophysiological and Neuroimaging techniques 14 biomedica Integrative, Functional, and Cognitive Neuroscience , RF ANTI INFLAMMATORY ACTIVITY OF POLYPHENOLS IN CANCER CHEMOPREVENTION 14 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Phase I adoptive immunotherapy study using the anti EGFR monoclonal antibody, cetuximab, low dose IL 2 and allogenic NK cell infusion after immunosuppressive therapy in non transplanted patients with metastatic colorectal cancer 14 biomedica Oncology 2 Clinical 866 RF Chemokine decoy receptors as new pharmacological targets: the D6 case of study 14 biomedica Immunology , RF HIV associated neurocognitive disorders in the HAART era: epidemiology, neuropathogenesis, clinical features, treatment responses and impact on health services 14 clinico assistenziale AS and Related Research , GR Investigating the molecular pathology of advanced colorectal cancer: coupling peptide signatures of the liver metastasis microenvironment with KRAS/BRAF mutational status for the design of alternative target therapies 14 biomedica Oncology 1 Basic 869 GR Optimization of the treatment in Non Small Lung Cancer: Impact of different types of K RAS mutations on tumour progression and drug sensitivity 14 biomedica Oncology 2 Clinical , RF High order social cognition in chronic neurological disorders 14 clinico assistenziale Brain Disorders and , RF STD s (sexual transmitted diseases) in a vulnerable population: a inmates cohort in Italy 14 clinico assistenziale AS and Related Research 872 RF Towards "All Laser" procedures in ophthalmic surgery TALL 14 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering ,00 Pagina 76 di 244

77 873 RF VENOUS THROMBOEMBOLISM IN KINDREDS WITH INHERITED THROMBOPHILIA: STRATIFICATION OF THE RISK IN THE CARRIER RELATIVES ACCORDING TO THE CLINICAL PHENOTYPE OF THE PROBAND. IMPLICATIONS FOR FAMILIAL LABORATORY SCREENING OF INDIVUALS WITH INHERITED THROMBOPH 14 clinico assistenziale Population Sciences and Epidemiology , RF Identification of an inflammatory signature of human colorectal cancer to seek candidate molecules as potential prognostic markers and/or therapeutic targets 14 biomedica Digestive, Kidney and Urological Systems , RF Vitamin B1 analogue benfotiamine for prevention of diabetic cardiomyopathy 14 biomedica Cardiovascular and , RF Cells and molecules of the innate immunity: potential molecular targets in diagnosis and therapy in cancer 14 biomedica Immunology 877 RF Autophagy in the pathogenesis of Gaucher's disease. 14 biomedica Genes, Genomes and , RF ANDROGEN DEPRIVATION THERAPY WITHDRAWAL VERSUS MAINTENANCE AND INTERMITTENT DOCETAXEL THERAPY VERSUS CONTINUOUS ADMINISTRATION IN HORMONE REFRACTORY PROSTATE CANCER PATIENTS. A PHASE III STUDY. 14 clinico assistenziale Oncology 2 Clinical , RF The role of SOD1 in nucleus: new insights in the pathogenesis of sporadic ALS 14 biomedica Molecular, Cellular, and Developmental Neuroscience RF Innovative phase Ib clinical trials based on patient genotype 14 biomedica Oncology 2 Clinical , , RF Improving specificity of brain iron mapping for the study of physiological and pathological aging 14 biomedica Brain Disorders and , RF Identification of progression markers for a clinical impact in cutaneous metastatic melanoma 14 biomedica Oncology 2 Clinical , RF Defining the role of the Erk8 MAP kinase in thyroid cancer 14 biomedica Oncology 1 Basic ,00 Pagina 77 di 244

78 884 RF Radiation exposure of paediatric patients undergoing interventional radiology procedures 14 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , RF MECHANISMS OF ENPP1 MEDIATED MODULATION OF INSULIN ACTION AND SECRETION 14 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF The role of unconventional Myosin VI in prostate cancer 14 biomedica Oncology 1 Basic , GR The DNA damage response at telomeres: new aspects of a barrier against genomic instability and tumorigenesis. 14 biomedica Oncology 1 Basic , RF Epigenetics of cerebral tumors: in vitro studies and perspective clinical applications 14 biomedica Oncology 1 Basic , RF Amniotic Fluid Stem Cells (AFS): molecular markers of osteoblastic and neurogenic differentiation and preclinical investigations for the treatment of agerelated diseases. 14 biomedica Biology of Development and Aging , RF West Nile virus infection: Pathogenic mechanisms and development of new therapeutic tools 14 biomedica Infectious Diseases and Microbiology , RF MODELING AND THERAPEUTIC TARGETING OF THE H1 MUTATION IN GLIOMAS 14 biomedica Oncology 1 Basic , RF BIOMARKERS FOR TUBERCULOSIS 14 biomedica Infectious Diseases and Microbiology RF The Ligurian Palliative Care Demonstration Project 14 clinico assistenziale Healthcare Delivery and Methodologies 894 RF Host and microbial biomarkers in exhalate breath condensate and other accessible body fluids for Clinical and incipient tuberculosis detection 14 biomedica Immunology 895 RF Characterization of BRCA1 transcriptional regulation by Next generation sequencing 14 biomedica Oncology 1 Basic Pagina 78 di 244

79 896 RF OSTEOGENIC DIFFERENTIATION OF HUMAN ADIPOSE TISSUE DERIVED STEM CELLS: INVOLVEMENT OF EPIGENETIC MECHANISMS 14 biomedica Cell Biology , GR Dissecting host parasite interactions by RNA interference (RNAi) knock down of lipid raft proteins in human erythrocytes 14,1 biomedica Infectious Diseases and Microbiology 898 GR Role of Twist1 transcription factor in thyroid tumor progression 14,13 biomedica Oncology 1 Basic , GR MULTITHERAPEUTIC APPROACH TO THE SPINAL CORD INJURY BY SMART HYDROGEL DRUG DELIVERY 14,17 biomedica Brain Disorders and , RF Identification of new genetic factors of non medullary familial thyroid carcinoma and study of their interaction with the phenotype 14,17 biomedica Oncology 1 Basic , RF Italian Network on Hereditary Periodic Fevers: ITALIANFEVER 14,17 clinico assistenziale Healthcare Delivery and Methodologies 902 RF Prenylcysteine lyase, a novel pro oxidant low density lipoprotein associated protein: from biology to its role in atherosclerosis 14,2 biomedica Vascular and Hematology , GR Development and validation of a novel brain imaging method for the in vivo assessment of distinct patterns of connectivity disorders of consciousness 14,25 clinico assistenziale Brain Disorders and , RF Identification of new molecular targets in biliary carcinoma 14,25 clinico assistenziale Oncology 2 Clinical GR The neurobiology of working memory span in normal and pathological ageing 14,25 biomedica Brain Disorders and , , RF Induced Pluripotent Stem Cells and Exploration of Reprogramming Epigenetic Molecules for neurodegenerative disease 14,25 biomedica Emerging Technologies and Training in Neurosciences , GR A randomized controlled trial of metabolic intervention in breast cancer families 14,25 clinico assistenziale Risk, Prevention and Health Behavior , GR Identification of a novel prognostic operator independent methodology for the individualized assessment of lung water and fibrosis 14,25 biomedica Bioengineering Sciences and Technologies ,00 Pagina 79 di 244

80 909 GR ENTIFICATION OF PREDICTIVE BIOMARKERS FOR MULTIPLE MYELOMA AT FIRST RELAPSE 14,25 biomedica Oncology 2 Clinical , RF GENETIC CONTRIBUTION TO INHIBITORS DEVELOPMENT IN HEMOPHILIA A 14,25 clinico assistenziale Vascular and Hematology , RF The potential of mirnome screening for understanding the clinical response and the mechanism of action of SSRI antidepressant drugs 14,25 biomedica Biobehavioral and Behavioral Processes 912 GR Targeting Biomarkers of Glaucoma in the Trabecular Meshwork: understanding Pathophysiology to Point Towards New Diagnostic and Therapeutic Strategies for Glaucoma 14,25 biomedica Brain Disorders and , GR EFFECTS OF BOTULINUM TOXIN A INJECTION IN THE DETRUSOR MUSCLE AND HIGH FREQUENCY REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION OVER FRONTAL AREAS IN PATIENTS WITH NEUROGENIC OVERACTIVE BLADDER SYNDROME DUE TO PARKINSON S DISEASE AND MULTIPLE SCLEROSIS: INS 14,25 clinico assistenziale Brain Disorders and , RF Implementation of a novel mechatronic paradigm for management, rehabilitation and restoration of motor functioning in patients with disorders of consciousness 14,25 clinico assistenziale Emerging Technologies and Training in Neurosciences , RF Optimization of human oocytes vitrification procedure through the randomized clinical application of an open protocol versus a closed protocol 14,25 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF PARKINSON S DISEASE AS A MULTIFACTORIAL DISORDER: CLINICAL AND PRE CLINICAL INVESTIGATION OF POTENTIAL BIOMARKERS FOR RISK ASSESSMENT AND MONITORING OF DISEASE PROGRESSION AND COMPLICATIONS OF LONG TERM L DOPA THERAPY 14,25 biomedica Brain Disorders and , RF Target enrichment and massively parallel sequencing to discover the cause of Schwannomatosis, a rare mendelian disorder. 14,25 biomedica Genes, Genomes and 918 RF Assessment of the allergic risk in the newborn and development of clinical practice guidelines for risk monitoring and allergy management. 14,25 biomedica Risk, Prevention and Health Behavior ,00 Pagina 80 di 244

81 919 GR Assessment of an adaptive response in patients with thyroid diseases after iodine 131 metabolic therapy 14,25 biomedica Oncology 2 Clinical , RF Role of Copy Number variations in determining the individual susceptibility to essential hypertension 14,25 biomedica Cardiovascular and , GR Relevance of host factors in the pathogenesis of HCV related lymphoproliferative disorders 14,3 biomedica Oncology 1 Basic , RF Cancer pain classification in palliative care. Clinical and genetic determinants of comprehensive management outcome 14,34 clinico assistenziale Oncology 2 Clinical , GR The neural architecture of temporal processing 14,34 biomedica Biobehavioral and Behavioral Processes , RF Study of the involvement of mutant p53 gain of function in tumor microenvironment 14,34 biomedica Oncology 1 Basic , GR Attentional selection under alcohol consumption: Psychophysical and neural correlates of attention impairment 14,34 biomedica Biobehavioral and Behavioral Processes , GR Arachidonic acid activated Ca2+ channel as potential target for tumor angiogenesis interference 14,38 biomedica Oncology 1 Basic , GR Prognostic role of follow up in melanoma patients. A prospective, randomized, trial. 14,5 clinico assistenziale Healthcare Delivery and Methodologies , RF Adaptation, operation and analysis of the biological effects on tumour cellular models of photoneutron converters (BNCT) at clinical LINAC's with real time neutron dosimetry. 14,5 biomedica Oncology 1 Basic , RF A comprehensive treatment for locally advanced breast cancer patients according to different biological features 14,5 clinico assistenziale Oncology 2 Clinical , RF General practice vs specialist based follow up for patients with colon cancer: a randomised controlled trial 14,5 clinico assistenziale Population Sciences and Epidemiology ,00 Pagina 81 di 244

82 931 GR Prognostic value of cross sectional and long term changes of grey matter structure and functional reorganization for physical disability and cognitive impairment in people with Multiple Sclerosis 14,5 clinico assistenziale Brain Disorders and , RF Ultrasound in physical therapy: a clinical and economical evaluation 14,5 clinico assistenziale Musculoskeletal, Oral and Skin Sciences , RF A novel approach to understanding the role of mtor in immunity and cancer 14,5 biomedica Immunology , RF Design of novel rational therapeutic strategies for RET driven medullary thyroid carcinoma 14,5 biomedica Oncology 1 Basic , GR Predictors of sleepiness related accidents in sleep disorders with excessive daytime sleepiness: from a laboratory based driving simulator approach to real road accident risk. 14,5 clinico assistenziale Risk, Prevention and Health Behavior , GR An open source, platform independent, WEB based implementation of IHE radiological and nuclear medicine workflow. 14,5 biomedica Healthcare Delivery and Methodologies , GR MATCH: Multidisciplinary Approach to brain Tumours in CHildhood 14,5 clinico assistenziale Population Sciences and Epidemiology , GR Relevance of Toll like Receptor 9 in lung carcinoma 14,5 biomedica Immunology , RF TM9SF4 A NEW PROTEIN ASSOCIATED TO THE METASTATIC PHENOTYPE OF HUMAN MELANOMA. A POTENTIAL NEW TARGET FOR ANTI CANCER STRATEGIES 14,5 biomedica Oncology 1 Basic , GR A simple method for estimating global DNA methylation using micro fluidic device with single nucleotide resolution 14,5 biomedica Bioengineering Sciences and Technologies , GR Interplay between PGE 2 and HIF 1 alpha in tumor progression and angiogenesis. 14,5 biomedica Oncology 2 Clinical , GR A different vasopressor approach during cardiopulmonary resuscitation: evaluating the effects of administration of the short acting beta 1 adrenergic blocker agent, esmolol, in combination with epinephrine, on outcome of cardiac arrest. From the experimen 14,5 clinico assistenziale Cardiovascular and ,00 Pagina 82 di 244

83 943 RF Prevention of peripartum, postnatal and breastfeeding HIV transmission in pregnant HIV infected women treated with HAART in the uran and rural areas of Dodoma Tanzania 14,5 clinico assistenziale AS and Related Research , GR Role of Notch in neuroplasticity : implication for cerebral palsy neurorehabilitation 14,5 biomedica Brain Disorders and , GR An Innovative Biotech Approach to Reduce Parkinson's Disease Neurodegeneration by Hydrogel assisted Delivery of Autologous Engineered Fibroblasts 14,5 biomedica Emerging Technologies and Training in Neurosciences , GR EFFECT OF FLUTICASONE FUROATE ON THE IL 23/TH17 AXIS IN CHRONIC RHINOSINUSITIS 14,5 biomedica Immunology , GR Motor and autonomic phenotypes associated with GRN and MAPT mutations in frontotemporal lobar degeneration 14,5 clinico assistenziale Brain Disorders and , RF Proteomic analysis of the saliva: a new tool for diagnosis and classification of rheumatoid arthritis and early rheumatoid arthritis 14,5 biomedica Biological Chemistry and Macromolecular Biophysics , RF ASSESSMENT OF PRESCRIBING APPROPRIATENESS IN GENERAL PRACTICE AND EVALUATION OF THE IMPACT OF EDUCATION AMONG PRACTITIONERS 14,5 clinico assistenziale Population Sciences and Epidemiology , GR A new approach for drug resistant epilepsy 14,5 biomedica Brain Disorders and RF Poligenic prediction of ischemic events after early onset myocardial infarction. 14,5 clinico assistenziale Cardiovascular and , , RF Novel strategies to deliver a bioactive molecule with antiproliferative properties to prostate cancer cells: melatonin in nanoparticles and as cryo laser therapy 14,5 biomedica Oncology 2 Clinical , GR A new approach to study alcoholism: evaluation of toxicity, tolerance and ethanol dependence mechanisms by molecular imaging, regulation of transcription and epigenetic analysis 14,5 biomedica Molecular, Cellular, and Developmental Neuroscience ,00 Pagina 83 di 244

84 954 GR FREEZING OF GAIT IN PARKINSON S DISEASE: FUNCTIONAL NEUROIMAGING, NEUROPHYSIOLOGICAL and PHARMALCOLOGICAL STUDY 14,5 clinico assistenziale Brain Disorders and , RF Adolescents and Young Adults Area Project. A dedicated unit for teenagers and young adult with cancer: towards a new clinical and translational research approach 14,5 clinico assistenziale Oncology 2 Clinical , GR Combined MR and PET imaging for monitoring stem cell therapies 14,5 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering 957 GR SLEEP DEPRIVATION, SLEEP DISORDERS, FATIGUE, STRESS AND THE RISK OF OCCUPATIONAL INJURIES AND ERRORS AMONG HEALTH CARE WORKERS: A MULTI APPROACH EPEMIOLOGICAL STUDY 14,5 clinico assistenziale Risk, Prevention and Health Behavior , RF Peptides from proteins of innate and adaptive immunity as new therapeutic agents against respiratory pathogens. 14,5 biomedica Infectious Diseases and Microbiology , GR Evaluation of the effectiveness of a multifactorial approach based on Intermittent Photic Stimulation, Cognitive and Physical Training and pharmacological treatment on slowing the progression of mild Alzheimer s Disease, identified in accordance with the 14,5 clinico assistenziale Brain Disorders and , GR A multimodal approach to disorders of consciousness: integrating neurophysiological signal processing and functional neuroimaging 14,5 biomedica Brain Disorders and , RF Colonoscopy based on Actively Propelled and Steerable capsule (CAPSULE): design, development and preclinical assessment of a novel device for truly endoscopic colorectal cancer screening and diagnosis. 14,5 biomedica Digestive, Kidney and Urological Systems , GR Defining the intrinsic role of NF kappab canonical signaling in chondrocytes in OA disease onset and progression in an inducible, IKKbeta deleter mouse model 14,5 biomedica Musculoskeletal, Oral and Skin Sciences , RF Characterization of cancer stem cells heterogeneity in human glioblastomas 14,5 biomedica Oncology 1 Basic ,00 Pagina 84 di 244

85 964 GR DNA Methylation Abnormalities in Blood Cells of Schizophrenic Patients with history of suicide attempts: Identification of epigenetic marks of schizophrenia and suicide risk for diagnostic purposes and prediction of drug responsiveness 14,5 biomedica Brain Disorders and , RF Molecular mechanisms underlying organic acidurias identified in newborn screening 14,5 biomedica Genes, Genomes and , GR MicroRNAs as predictive biomarkers target in rare paediatric tumors 14,5 biomedica Oncology 2 Clinical , RF Autologous dendritic cells immuno therapy in HIV positive patients: a genomic approach 14,5 biomedica AS and Related Research , RF Vaccine against Staphylococcus aureus implant related infections (VASARI) 14,5 biomedica Immunology , RF Improving diagnosis and management of patients with cerebellar ataxias by a comprehensive molecular screening of the known genetic forms, a systematic phenotypic classification of sporadic cases, and search for new disease genes in undefined familial case 14,5 clinico assistenziale Brain Disorders and , RF Molecular signatures in liver lesions as paradigm for discovery of new biomarkers and therapeutic targets 14,5 biomedica Oncology 2 Clinical , RF CLINICAL, NEUROIMAGING AND MOLECULAR STUDIES BY NEXT GENERATION SEQUENCING OF MLINE BRAIN ABNORMALITIES ASSOCIATED WITH PITUTARY HORMONE DEFICIENCIES: A MULTI DISCIPLINARY NETWORK 14,5 clinico assistenziale Genes, Genomes and 972 RF ENTIFICATION OF GENETIC DETERMINANTS OF STROKE IN AN ANIMAL MODEL OF A COMPLEX HUMAN DISEASE 14,5 biomedica Genes, Genomes and , RF Impact of Antiretroviral Therapy on Viral Replication and Immune Restoration in the Gut associated Lymphoid Tissue of HIV infected Patients. 14,5 clinico assistenziale AS and Related Research , RF Molecular Phenotyping of Chronic Obstructive Pulmonary Disease. 14,5 biomedica Cardiovascular and ,00 Pagina 85 di 244

86 975 RF Development, in vitro testing and in vivo validation of novel drugs targeting the interaction between the urokinase receptor and the extracellular matrix protein vitronectin: exploiting a novel avenue for the interference with tumor growth, invasion and m 14,5 biomedica Oncology 1 Basic , RF Oxidative DNA damage and protection of neurodegeneration by the hmth1 hydrolase: therapeutic approaches in cellular and animal models 14,5 biomedica Molecular, Cellular, and Developmental Neuroscience , RF DEVELOPMENT AND VALATION OF A WIRELESS POLYGRAPHIC DEVICE FOR REMOTELY ATTENDED HOME MONITORING AND DIAGNOSIS OF SLEEP DISORDERS 14,5 clinico assistenziale Emerging Technologies and Training in Neurosciences , RF Mechanisms of neurodegeneration and phenotypic heterogeneity in inherited prion diseases: physiopathological involvement of prion proteins in membrane trafficking and signaling 14,5 biomedica Brain Disorders and , RF From humans to mice and return: comparative analysis among patients and NCL's mouse models 14,5 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Novel BNCT Clinical Approach to Osteosarcoma 14,67 clinico assistenziale Oncology 2 Clinical RF IKKalpha as a novel therapeutical target in osteoarthritis 14,67 biomedica Musculoskeletal, Oral and Skin Sciences , , RF Significant predictors of risk behaviours and mental health outcomes in adolescent immigrants to Italy compared to a national sample of native Italians 14,75 clinico assistenziale Risk, Prevention and Health Behavior , RF Prognostic role of circulating tumor cells in stage I III colorectal cancer 14,75 clinico assistenziale Oncology 2 Clinical , GR Predict and Prevent Reading Acquisition Disorders: Developmental and Cognitive Neuroscience of Dyslexia 14,75 biomedica Biobehavioral and Behavioral Processes , GR Genetic and psychosocial determinants of the outcome of Bipolar depression. 14,75 biomedica Brain Disorders and ,00 Pagina 86 di 244

87 986 RF GENETIC PREDISPOSITION AND MECHANISMS OF INTESTINAL FIBROSIS IN CROHN S DISEASE: BASIS FOR THERAPEUTIC AND DIAGNOSTIC INTERVENTION 14,75 clinico assistenziale Genes, Genomes and , GR Early cardiac dysfunction predictive of clinically significant Trastuzumab induced cardiac damage in the neoadjuvant, adjuvant and metastatic setting and its correlation with biological markers of chronic inflammation and oxidative stress. Proposal of a c 14,75 clinico assistenziale Oncology 2 Clinical , RF Phosphorylated alpha enolase isoforms as diagnostic and prognostic tools in pancreatic cancer 14,75 biomedica Oncology 2 Clinical , GR Exploring immune gene regulation by micrornas in multiple sclerosis: from candidate to modifier genes 14,75 biomedica Brain Disorders and 990 RF Autoimmune pancreatitis mimicking pancreatic cancer: pathogenetic mechanisms and serological markers. 14,75 biomedica Immunology , RF How hepatitis C virus exploits the lipoproteins machinery: development of new antiviral strategies. 14,75 biomedica Infectious Diseases and Microbiology , GR EARLIEST ANTENATAL DIAGNOSIS OF GENETIC DISEASES AND CHROMOSOMAL ABNORMALITIES BY COELOMIC FLU SAMPLING 14,75 biomedica Healthcare Delivery and Methodologies , GR MicroRNA profile in blood as novel biomarker in Amyotrophic Lateral Sclerosis 14,75 biomedica Brain Disorders and , GR Phase II study of neoadjuvant Cisplatin, Gemcitabine plus Sorafenib for transitional cell carcinoma of the bladder. 14,75 clinico assistenziale Oncology 2 Clinical , RF Dietary fat, inflammatory status and breast cancer risk in the ORDET (Hormones and Diet in Etiology of Tumors) prospective cohort 14,75 clinico assistenziale Population Sciences and Epidemiology , RF Circulating biomarkers for the diagnosis, prognostic stratification and assessment of response to treatment in hepatocellular and cholangiocellular carcinomas 14,75 biomedica Oncology 2 Clinical , GR Definition of new biomarkers and methodologies for the evaluation of the quality of aging: a biomedical, genetic and statistic multidisciplinary approach 14,75 biomedica Genes, Genomes and ,00 Pagina 87 di 244

88 998 GR Analysis of ribavirin plasma concentration: evaluation of the possible role in predicting virological responses and in monitoring toxicity in patients with chronic hepatitis C 14,75 clinico assistenziale Infectious Diseases and Microbiology , RF Study on target therapies Impact in breast cancer patients on a wide area of northern Emilia (AVEN ) Population included in the Reggio Emilia, Modena, Parma, Piacenza Tumour Registry 14,75 clinico assistenziale Oncology 2 Clinical , RF Prevention and management of symptom burden in cancer patients: from biological pathways to behavioral interventions 14,75 clinico assistenziale Risk, Prevention and Health Behavior 1001 GR Identification of candidate modifier and disease causing genes for Multiple Osteochondromas by genome wide SNP/CNV genotyping 14,75 biomedica Genes, Genomes and , RF Development of a multigene classifier for the prediction of the response to Metformin of HER2 negative metastatic breast cancer patients based on the expression of genes of the insulin/igf pathway in circulating tumor cells 14,75 biomedica Oncology 2 Clinical , RF HPV genotyping and evaluation of viral and cancer biomarkers for the triage of anal HPV related lesions in HIV/HPV coinfected patients 14,75 clinico assistenziale Oncology 2 Clinical , GR The p53 network in breast cancer aggressiveness: new regulatory levels and molecular targets for diagnosis and therapy. 14,75 biomedica Oncology 1 Basic , RF High resolution mapping of genomic structural variation in the general Italian population 14,75 biomedica Genes, Genomes and , RF Nuclear Activation of the Innate Immune Kinase PKR as a Potential Therapeutic Target and Marker for Disease Progression and Therapeutic Response in Myelodysplastic Syndromes and Acute Leukemia 14,75 biomedica Vascular and Hematology , RF Individualisation and optimization of antidepressant therapy: from the genetic to clinical observation. 14,75 clinico assistenziale Emerging Technologies and Training in Neurosciences , GR Biomarkers of cardiovascular risk and inflammation: potential association with Alzheimer's disease progression and subsequent conversion of mild cognitive impairment to dementia 14,75 biomedica Genes, Genomes and ,00 Pagina 88 di 244

89 1009 RF Cisplatin, Docetaxel and Capecitabine Followed by Cetuximab and Radiotherapy in Locally Advanced Inoperable Head and Neck Cancer. A Phase I/II Study with Prognostic Evaluation of Biological Parameters. 14,75 biomedica Oncology 2 Clinical , GR A study of defensins and innate immunity genes as candidate genetic factors for HPV infection and HPV related cancer development 14,75 biomedica Genes, Genomes and , RF Molecular epidemiology of male breast cancer in Tuscany: genetic alterations and environmental factors 14,84 biomedica Oncology 1 Basic , GR Advanced strategies for maternal and fetal medicine: analysis of fetal nucleic acids in maternal plasma for noninvasive prenatal diagnosis of fetal genetic diseases and monitoring of pregnancy complications 14,84 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF USE OF NATURAL PEPTES AS ANTIBACTERIAL AGENTS IN FOOD PRESERVATION 14,84 biomedica Veterinary Food Safety FOSA , RF EXPERIMENTATION OF LICENSED BONE MARROW DERIVED MESENCHYMAL STROMAL CELLS (MSCs) IN INTRACTABLE AUTOIMMUNE DISORDERS OF CHILDHOOD: A PIVOTAL TRIAL 14,84 biomedica Immunology , RF Novel molecular biomarkers predictive of individual response to therapy in human colorectal carcinoma 14,84 biomedica Oncology 1 Basic 1016 RF MicroRNA as modulators of gene expression during beta cell damage and regeneration: towards a novel therapeutic tool for cell therapy in diabetes mellitus 15 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Base excision repair as a therapeutic target in human cancer 15 biomedica Oncology 1 Basic 1018 GR Cognitive and neural plasticity in aging: Behavioral and neurophysiological approaches in memory training 15 biomedica Biobehavioral and Behavioral Processes , RF Autism: clinical and genetic correlation in a regional based study 15 biomedica Brain Disorders and ,00 Pagina 89 di 244

90 1020 GR Role of MYC in orchestrating epigenetic events in Embryonic and Cancer Stem Cells 15 biomedica Genes, Genomes and , GR EXPLOITING DIFFERENTIATION AND APOPTOSIS TO FIGHT AGAINST THE HETEROGENEITY OF BREAST CANCER. 15 biomedica Oncology 1 Basic , GR PULSED ELECTROMAGNETIC FIELD (PEMF) AS ADJUVANT TREATMENT FOR OSTEOCHONDRAL TISSUE REGENERATION OF THE KNEE: FROM PRECLINICAL STUDY TO CLINICAL APPLICATION. 15 clinico assistenziale Musculoskeletal, Oral and Skin Sciences , RF Constitutive activation of multiple receptor tyrosine kinases in a subset of human melanomas: identification of common and specific intracellular pathways for therapeutic intervention 15 biomedica Oncology 1 Basic , GR Novel inhibitors targeting entry of herpes virus type 1 15 biomedica Infectious Diseases and Microbiology , GR Dreaming as a model for psychosis: EEG measurements across states of the brain/mind 15 clinico assistenziale Brain Disorders and , RF Endocrine disrupters and effects on thyroid function: bridging toxicology and clinical endocrinology to characterize mechanisms, biomarkers and potential risks for health, growth and development (EDUCT) 15 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences 1027 RF IMPACT OF AN INTEGRATED REHABILITATION PROGRAM FOR HEAD AND NECK CANCER PATIENTS ON QUALITY OF LIFE, PATIENT REPORTED AND FUNCTIONAL OUTCOMES 15 clinico assistenziale Healthcare Delivery and Methodologies , RF Suicide Prevention in Italian Regions 15 clinico assistenziale Risk, Prevention and Health Behavior , RF Arterial calcification in chronic kidney disease: diagnosis, development and cardiovascular complications 15 clinico assistenziale Vascular and Hematology , RF MESENCHYMAL STEM CELL FROM PLACENTA:IMMUNOMODULATION PROPRIETES AND CLINICAL USE 15 biomedica Immunology ,00 Pagina 90 di 244

91 1031 RF Novel multi scale approach to 3D cancer models for the discovery of new therapeutic strategies for patients with bone metastatic lesions 15 biomedica Oncology 1 Basic 1032 GR Cognitive and imaging correlates of brain Abeta amyloidosis in healthy adults 15 clinico assistenziale Brain Disorders and , GR Involvement of micrornas in breast cancer driving pathways: from biology to possible therapies. 15 biomedica Oncology 1 Basic , GR Genomic instability in healthy tissues after cancer radiotherapy: implications for long term effects 15 biomedica Oncology 2 Clinical , GR Impaired Cardiac Metabolism during Heart Faliure: Role of the Beta 2 Adrenergic Receptor 15 biomedica Cardiovascular and , GR TelMedOb Low cost TeleMedicine solutions for the treatment of Obesity with and without Type 2 Diabetes in out patient settings 15 clinico assistenziale Risk, Prevention and Health Behavior , GR Multifunctional nanocarriers for drug delivery, cellular and molecular imaging as potential therapeutic and diagnostic tools for pediatric tumors 15 biomedica Bioengineering Sciences and Technologies 1038 RF A strategy for the implementation of Patient Tailored Chronochemotherapy 15 clinico assistenziale Oncology 1 Basic 1039 RF Efficacy and effectiveness of early and intensive rehabilitation interventions in patients with recent stroke. A randomized controlled study 15 clinico assistenziale Brain Disorders and , RF A research project on management methodologies, which will help improving diagnosis, treatment and scientific research in oncology through an integrated network connecting the Sardinian territory to national IRCCS 15 clinico assistenziale Healthcare Delivery and Methodologies , GR Adoptive Immunotherapy with Cytokine Induced Killer Cells for the Treatment of Bone sarcomas: Preclinical Model and Clinical Application 15 biomedica Oncology 2 Clinical , RF Ultrasound susceptibility of botulinum neurotoxins and botulinum neurotoxinproducing clostridia 15 biomedica Veterinary Food Safety FOSA , GR Role of OX40L triggering on mast cell functions 15 biomedica Immunology ,00 Pagina 91 di 244

92 1044 GR Integromic analysis of the DNA damage repair networks in patients affected by rectal cancer undergoing neo adjuvant treatment with capecitabine and ionizing radiation 15 biomedica Oncology 1 Basic , GR MicroRNA control of prostate cancer metastasis 15 biomedica Oncology 1 Basic GR Genetic of Major depressive disorder 15 biomedica Genes, Genomes and , , RF Neuropeptides and Neprilysin involvement in pancreatic cancer: from pain pathogenesis to cancer progression 15 biomedica Oncology 1 Basic , GR Molecular Mechanisms in Invasive Thyroid Tumors 15 biomedica Oncology 1 Basic , RF Incidence of the histotypes and related variants of thyroid cancer in Western Emilia, including the provinces of Parma, Piacenza, and Reggio Emilia, clinico assistenziale Oncology 2 Clinical , RF Hypoxia and Danger signals in Erdheim Chester Disease microenvironment: insights on the pathogenesis and implications for therapy 15 biomedica Immunology , RF Identification of prognostic and therapeutic biomarkers in patients with high risk musculoskeletal sarcomas by profiling post transcriptional and post translational molecular networks. 15 biomedica Oncology 1 Basic , RF Mechanisms and sources of infection in the main food borne zoonoses pathogens and definition of innovative methodologies for human disease prevention, through the implementation of a surveillance network. 15 biomedica Veterinary Food Safety FOSA 1053 RF Late Presentation of HIV Infected Individuals: Evaluation of Epidemiological, Clinical And Immunological Implications in Order to Optimize Treatment Outcome. 15 clinico assistenziale AS and Related Research , GR Lung ultrasound for diagnosis, follow up and prognosis of cardiopulmonary disease 15 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering ,00 Pagina 92 di 244

93 1055 GR New strategies for treatment of meningococcal meningitis: therapeutic effects of L glutamate analogues in animal models 15 biomedica Infectious Diseases and Microbiology , RF Phosphatonins role in bone mineralization process 15 biomedica Genes, Genomes and GR Identifying expression dysregulation associated with autism 15 biomedica Genes, Genomes and , , GR Isolation and characterization of invasive E coli strains and analysis of their influence on innate immune response in pediatric patients with inflammatory bowel disease 15 biomedica Digestive, Kidney and Urological Systems , RF Non traditional vascular, metabolic and inflammatory predictors of silent coronary artery disease and of cardiovascular events in type 2 diabetes mellitus: potential impact on guidelines. 15 clinico assistenziale Cardiovascular and , GR Role of Cyclophilin D in tumorigenesis 15 biomedica Oncology 1 Basic , RF Discovery Proteomic Analysis of Human Ovarian Cancer Stem Cells and Functional Validation of Targets 15 biomedica Oncology 2 Clinical , GR 'Cancers of unknown primary origin' (CUPs): a pathology driven by the Met oncogene 15 biomedica Oncology 1 Basic , GR Post Genome Wide Association study: biological and prognostic significance of alcohol dehydrogenase gene polymorphisms in head and neck cancer patients 15 biomedica Population Sciences and Epidemiology , GR Targeting strategies in Numb defective cancers 15 biomedica Oncology 1 Basic GR Environmental influence on motor learning in disability conditions 15 clinico assistenziale Brain Disorders and , , GR A novel link between complement and thrombosis promotes cardiovascular events in type 2 diabetes 15 biomedica Vascular and Hematology ,00 Pagina 93 di 244

94 1067 RF Stathmin expression and ovarian carcinoma: searching for a new prognosis marker and new therapeutic approaches. 15 biomedica Oncology 1 Basic , RF Characterization of proteome alterations induced by Mycobacterium tuberculosis in human dendritic cells to develop new TB vaccination strategies. 15 biomedica Immunology , RF Characterization of the mechanisms regulating mononuclear phagocyte protumoral activity within the tumor hypoxic microenvironment: potential therapeutic applications 15 biomedica Oncology 1 Basic , GR New immunopahtological based diagnostic and therapeutic strategies in dermatitis herpetiformis and celiac disease 15 biomedica Musculoskeletal, Oral and Skin Sciences , RF Rapid diagnosis and molecular characterization of B. pertussis infection: relationship with epidemiology, vaccine efficacy, and clinical presentation 15 biomedica Infectious Diseases and Microbiology , GR SEARCH FOR BEST CRITERIA TO PREDICT ARRHYTHMOGENIC RISK IN CARDIOMYOPATHIES CAUSED BY MUTATIONS OF GENES CODING DESMOSOME PROTEINS 15 clinico assistenziale Cardiovascular and , RF FATTY ACS COMPLEMENTATION FOR THE TREATMENT OF SCHIZOPRENIA (FACTS): A DOUBLE BLIND, RANDOMIZED CONTROLLED TRIAL 15 clinico assistenziale Biobehavioral and Behavioral Processes , GR Establishment and Characterization of cytotoxic T lymphocytes for immunotherapy of JC virus Associated Progressive Multifocal Leukoencephalopathy 15 biomedica Immunology , GR The role of beta catenin in T cell mediated inflammatory and neurodegenerative processes. 15 biomedica Brain Disorders and , RF Investigation of Norovirus strains with putative zoonotic potential in pet animals in Italy. Implementation of diagnostic assays, molecular characterization and phylogenesis, host restricted binding. 15 biomedica Veterinary Animal Health ANHE , GR Lymphatic endothelial dysfunction is involved in the pathogenesis of systemic sclerosis 15 biomedica Vascular and Hematology ,00 Pagina 94 di 244

95 1078 GR Dissecting the metastatic process: identification of novel biomarkers improving clinical management of aggressive cancers. 15 biomedica Oncology 1 Basic , GR Monitoring of heart failure: a new non invasive method 15 biomedica Cardiovascular and , GR Exploring the Autophagy pathway in Amyotrophic Lateral Sclerosis related Motor Neuron death 15 biomedica Brain Disorders and , RF Generation and development of monoclonal antibodies recognising tumor stem cells in colorectal and lung cancer 15 biomedica Oncology 2 Clinical , RF Knowledge dissemination as a basis for health promotion and prevention in chronic conditions: focus on cardiovascular health 15 clinico assistenziale Risk, Prevention and Health Behavior , RF Guided bone regeneration with innovative degradable scaffolds: preclinical evaluation 15 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , GR Innate immunity and autoimmunity in myasthenia gravis: outcomes of Epstein Barr virus infection and Toll like receptor signaling pathways in B cell function 15 biomedica Immunology , RF High throughput genomic profiling of autistic patients grouped on the basis of biochemical differences 15 biomedica Genes, Genomes and , RF Exploitation of the sublingual route of immunization for mucosal vaccine against HIV biomedica AS and Related Research , GR How to evaluate Efficacy In the framework of cost effectiveness analysis for Growth Hormone (rhgh) Therapy in paediatric patients with Growth Hormone deficiency (HEIGHT) 15 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF KIR/HLA phenotypes and genotypes in HIV infected elite natural controller subjects and comparative analysis of molecular mechanisms of innate immune responses. 15 biomedica AS and Related Research , RF Identification of novel synthetic and natural compounds for the development of new drugs targeting vector borne protozoan parasites 15 biomedica Infectious Diseases and Microbiology ,50 Pagina 95 di 244

96 1090 RF Enlightening activation of the ocular albinism type 1 protein (OA1) on intracellular organelles by protein complementation assays and correlative light electron microscopy 15 biomedica Cell Biology , RF The clinical impact of genetic predictors on the treatment of drug resistant epilepsy in tuberous sclerosis complex 15 biomedica Genes, Genomes and , RF Dissecting the role of NOD2 in the modulation of gut inflammation and fibrosis: relevance for Crohn s Disease 15 biomedica Immunology , RF CELLULAR AND ANIMAL SYSTEMS IN MODELING HUMAN DISORDERS DUE TO ALTERED CONTENT AND/OR STABILITY OF mtdna ASSOCIATED WITH MILD METHYLMALONIC ACURIA 15 biomedica Brain Disorders and , RF Molecular characterization of and therapeutic approach to muscle fibrosis in Duchenne muscular dystrophy 15 biomedica Musculoskeletal, Oral and Skin Sciences , RF ITALIAN SURVEY OF SERVICES AND PATHWAYS OF CARE FOR CHILDREN AND ADOLESCENT NEUROPSYCHYATRIC DISORDERS 15 clinico assistenziale Healthcare Delivery and Methodologies , RF Caveolin 1 modulation of tumor associated macrophages (TAM) function 15 biomedica Oncology 1 Basic , RF A CHARACTERISATION OF THE ALZHEIMER S DISEASE AND OF THE FRONTO PARIETAL DEMENTIA BASED ON A BIOCHEMICAL STUDY OF MICRO VESICLES PRESENT IN LIQUOR AND PLASMA SAMPLES 15 biomedica Brain Disorders and , RF Evaluation of the effectiveness of ADL based exercises Vs point to point reaching tasks in robot mediated therapy of the upper limb for sub acute stroke patients 15 biomedica Musculoskeletal, Oral and Skin Sciences 1099 RF Clinical genetic study of Parkinson disease associated with glucosecerebrosidase mutations 15 clinico assistenziale Brain Disorders and , GR Role and Modulation of Jak and STAT signaling in Graft Rejection and Graft versus Host Disease 15 biomedica Immunology , GR Treatment of human melanoma xenograft by a potent, newly identified human CD8+ memory T cell subset 15 biomedica Immunology ,67 Pagina 96 di 244

97 1102 RF Fase 2b trial: oral corticosteroids vs intra erythrocyte dexamethasone (EryDex) for the treatment of the CNS symptoms of patients with Ataxia Teleangectasia 15 clinico assistenziale Brain Disorders and , GR Identification and functional validation of microrna biomarkers in lung cancer 15 biomedica Oncology 1 Basic , RF Mitochondrial succinate dehydrogenase (SDH) mutations and pheochromocytoma/paraganglioma syndromes: biochemical and functional in vitro and in vivo (animal xenograft model) consequences of different SDH mutations. 15 biomedica Oncology 1 Basic , RF Identification of expression networks as effectors of genetic susceptibility to lung cancer in a segregating mouse population 15 biomedica Genes, Genomes and , RF Pathogenesis of hemolytic uremic syndrome associated with Shiga toxinproducing Escherichia coli infections: understanding the mechanisms of toxin delivery from the gut to the target organ endothelia by clinical observations on patients with bloody diarrh 15 biomedica Infectious Diseases and Microbiology , RF Sensitizing glioma stem cells to radiotherapy and chemotherapy with cell cycle checkpoint and DNA repair inhibitors 15 biomedica Oncology 2 Clinical , RF STUDY OF DIAGNOSTIC AND THERAPEUTIC INTERVENTIONS FOR ALLERGIC DISEASES IN LOMBARDY BY COST UTILITY ANALYSIS 15 clinico assistenziale Healthcare Delivery and Methodologies , RF Transition from commensal to nosocomial bacterial pathogens: an integrated approach for population based and lateral virulence gene transfer studies on hospital adapted streptococci and enterococci. 15 biomedica Infectious Diseases and Microbiology , RF Human Herpes virus 8 (HHV8) infection in transplanted patients: prevalence, seroconversion and Kaposi's Sarcoma development after transplantation. 15 clinico assistenziale Infectious Diseases and Microbiology , RF Novel Diagnostic Biomarkers for Global Brain Dysfunction following Aneurysmal Subarachnoid Hemorrhage and Therapeutic Intervention 15 biomedica Brain Disorders and , RF Second generation of prophylactic and therapeutic vaccines against HPV and related cancers. 15 biomedica Oncology 2 Clinical ,00 Pagina 97 di 244

98 1113 RF Clinical testing and mechanistic evaluation of caffeine as a potential therapeutic option for Alzheimer's disease. 15 clinico assistenziale Brain Disorders and , RF CELL CHARACTERIZATION AND ANALYSIS OF THE PROLIFERATIVE/DIFFERENTIATIVE POTENTIAL OF HUMAN COELOMIC FLU CELLS FOR "IN UTERO" HAEMATOPOIETIC STEM CELL TRANSPLANTATION IN HAEMOGLOBINOPATHIES 15 biomedica Vascular and Hematology , RF Long QT syndrome type 2: functional characterization and identification of corrective strategies (GO QT2) 15 biomedica Genes, Genomes and , RF calorie restriction and cancer prevention: epigenetic and transcriptional mechanisms 15 biomedica Oncology 1 Basic 1117 RF THE PHYSICAL CO MORBITY, HEALTH STATUS AND POOR HEALTH BEHAVIOUR OF TREATED PSYCHIATRIC PATIENTS WITH FUNCTIONAL PSYCHOSES. A multicentre prevalence study PHYSICO I 15 clinico assistenziale Population Sciences and Epidemiology 1118 RF Phatogenetic mechanism of Malignant Pleural Mesothelioma development 15 biomedica Oncology 1 Basic , RF Role of mglu2 and mglu3 metabotropic glutamate receptors in neurodegeneration/neuroprotection mechanisms 15 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Is the Mycobacterium avium subspecies paratuberculosis present in cows linked to human Crohn's disease? A microbiological, molecular and genetic approach to a long lasting issue 15 biomedica Veterinary Animal Health ANHE , RF New approaches for in situ monitoring of immune responses in melanoma patients treated with combined chemo immunotherapy 15 biomedica Oncology 2 Clinical , RF Residual morbidity and risk of relapse in patients cured of Cushing's syndrome 15 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences ,00 Pagina 98 di 244

99 1123 RF ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION WITH REDUCED INTENSITY CONDITIONING REGIMEN IN PATIENTS WITH HIGH RISK MYELOFIBROSIS: RANDOMIZED PHASE II STUDY BETWEEN FLUDARABINE PLUS BUSULPHAN OR THIOTEPA CONDITIONING REGIMENS 15 clinico assistenziale Vascular and Hematology , RF Systems biology for predictive biomarkers of responsiveness to cancer vaccines 15 biomedica Oncology 2 Clinical , RF PRESERVATION OF THE REPRODUCTIVE FUNCTION IN ONCOLOGICAL CHILDREN AND WOMEN AT RISK OF STERILITY: OVARIAN TISSUE CRYOPRESERVATION USING A NON CONVENTIONAL ANTI OXANT IN HYPERBARIC CONDITIONS 15,17 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Definition of the epigenetic signature in Multiple Myeloma by high resolution DNA methylation analysis; an integrative genomic approach with allelic imbalances and mrna microrna expression profiling. 15,17 biomedica Oncology 1 Basic , RF ATROPHY AND AUTOPHAGY AS KEY REGULATORS IN LIMB GIRDLE MUSCULAR DYSTROPHY AND IN METABOLIC MYOPATHIES 15,17 clinico assistenziale Musculoskeletal, Oral and Skin Sciences , RF Targeting the Met oncogene in osteosarcoma cancer stem cells 15,17 biomedica Oncology 1 Basic 1129 RF Role of mitochondria in triggering cell loss in Huntington disease: molecular mechanisms, animal models and preclinical studies for validation of innovative target for pharmacological therapy 15,17 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Redirecting T cells against prostate cancer by gene transfer of chimeric antigen receptors 15,25 biomedica Oncology 2 Clinical , RF New therapeutic strategies for the control of fungal infections in the elderly 15,25 biomedica Biology of Development and Aging , GR Design and assessment of rehabilitation strategies in stroke subjects by integrating robotics and neuroimaging 15,25 biomedica Emerging Technologies and Training in Neurosciences , RF Identification and validation of micrornas as novel biomarkers and therapeutic targets in prostate cancer 15,25 biomedica Oncology 2 Clinical ,00 Pagina 99 di 244

100 1134 GR Motor Imagery and Body Representation in Amiotrophic Lateral Sclerosis 15,25 clinico assistenziale Brain Disorders and , RF Broad functional monitoring of cellular and humoral immunity for rational posttransplant management of operational tolerance and infectious disease complications in liver transplant recipients undergoing immunosuppressive regimens with anti thymocyte glo 15,25 clinico assistenziale Immunology 1136 GR Prevention of tissue injury in diabetes: novel approaches for marker and target discovery 15,25 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR VIROLOGICAL, IMMUNOLOGICAL AND GENETIC STUDIES ON HIV INFECTED ITALIAN AND IMMIGRANT POPULATIONS IN ITALY. 15,25 clinico assistenziale AS and Related Research , RF MULTICENTRE COMPARATIVE STUDY OF AMITRIPTYLINE, CARBAMAZEPINE AND PREGABALIN FOR FIRST LINE THERAPY IN CHRONIC PERIPHERAL NEUROPATHIC PAIN: RANDOMIZED TRIAL (the PainPAD trial) 15,25 clinico assistenziale Emerging Technologies and Training in Neurosciences , GR Study of genetic bases of osteoporosis in a genetic isolate 15,25 biomedica Genes, Genomes and 1140 RF Mediastinoscopy versus endobronchial ultrasound transbronchial needle aspiration in the preoperative staging of lung cancer patients: a prospectiverandomized study 15,25 clinico assistenziale Oncology 2 Clinical , RF Identification of biomarkers to predict thrombosis in a high risk cohort of cancer patients undergoing bevacizumab based regimens. 15,25 clinico assistenziale Vascular and Hematology , GR Design of glycopeptides as biomarkers for multiple sclerosis 15,25 clinico assistenziale Brain Disorders and , RF NF kb signaling pathway, microbial infections and neurodegeneration in Alzheimer's disease. 15,25 biomedica Infectious Diseases and Microbiology , RF Natural history model of lung cancer: characterization of genetic changes and cellular populations determining tumor invasiveness 15,25 biomedica Oncology 2 Clinical ,00 Pagina 100 di 244

101 1145 GR Development of an innovative system for sensing the wave aberration of human eyes based on diffractive multiple shearing interferometry 15,25 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , GR Functional roles of MITOSTATIN, a novel putative Mitochondria Localized Tumor Suppressor protein 15,34 biomedica Oncology 1 Basic , GR Low cost alternative prognostic and diagnostic biochemical surrogate markers to monitor HIV disease progression 15,34 biomedica AS and Related Research , GR The hypoxic microenvironment in Neuroblastoma tumors: relationship with the aggressive tumor phenotype 15,34 biomedica Oncology 1 Basic , GR Mediators of inflammation and angiogenesis in Chronic Autoimmune Urticaria (CAU): new tools for the diagnosis and follow up 15,34 biomedica Immunology , GR Novel aspects of medical therapy and phisopathology of ACTH secreting pituitary tumors 15,34 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Telomere length: a new marker for diabetic complications? 15,34 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Role of the pancreatic cancer microenvironment in conditioning CD4+ adaptive antitumor immunity and vice versa 15,34 biomedica Immunology , RF Developing a computer aided diagnosis system for detection of prostate cancer using multispectral MRI 15,34 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , GR NANOVECTUCAM Nanovectors for Targeted Visualization and Treatment of Undetectable Unstable Coronary Atherosclerotic Plaques using Magnetic Resonance Imaging In Vivo 15,5 biomedica Vascular and Hematology , GR GENETIC SUSCEPTIBILITY TO OXATIVE DNA DAMAGE: FROM SINGLE NUCLEOTE POLYMORPHISMS TO FUNCTION 15,5 biomedica Genes, Genomes and ,00 Pagina 101 di 244

102 1156 GR Serotype distribution, antimicrobial resistance, and molecular characterization of Streptococcus pneumoniae isolates in two Italian regions from culture positive and culture negative clinical specimens 15,5 biomedica Infectious Diseases and Microbiology , GR A bright idea to detoxify CO poisoned patients 15,5 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Development, characterization and in vivo evaluation of innovative pharmaceutical formulations of the new potent painkiller peptide opiorphin 15,5 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Molecular characterization and functional analysis of amniotic fluid stem cells driven toward smooth muscle cell lineage potential for regenerative medicine 15,5 biomedica Cell Biology , RF Role of MET and MYC regulation in resistance to anti EGFR agents in colorectal and non small cell lung cancer 15,5 clinico assistenziale Oncology 2 Clinical , GR Genistein effects on phosphorylated Tau in Alzheimer Disease investigated by Surface Enhanced RAMAN spectroscopy 15,5 biomedica Brain Disorders and , GR Preclinical testing of phosphoinositide 3 kinases as therapeutic targets in heart failure 15,5 biomedica Cardiovascular and 1163 RF BIOCHEMICAL AND TISSUTAL RESPONSES IN FISH OF COMMERCIAL INTEREST FED MELAMINE AND CYANURIC AC ENRICHED DIETS EVALUATING THE RISK ASSESSMENT FOR ANIMAL AND HUMAN HEALTH 15,5 biomedica Veterinary Animal welfare ANWE , RF A novel therapeutic approach for the cure of advanced prostate cancer 15,5 biomedica Oncology 2 Clinical , GR Lung adenocarcinoma genomic initiative: characterization of oncogenic abnormalities and target validation in pulmonary adenocarcinoma 15,5 biomedica Oncology 2 Clinical , RF Evaluation of anti TAT immunity (T and B) in the clinical, immunological and virological pathogenesis and progression of AS patients 15,5 biomedica AS and Related Research , GR MYH9 related disease: development of a strategy to genetically engineer mouse embryonic stem (ES) cells at high efficiency 15,5 biomedica Genes, Genomes and ,00 Pagina 102 di 244

103 1168 RF A Phase I/II, Multicentre, Open label, Repeated Dose Range Finding Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of Bortezomib in association with Topotecan, Vincristine and Doxorubicine (TVD) in subjects with relapsed or refra 15,5 biomedica Oncology 2 Clinical , GR Study of the viral and host correlates of mixed cryoglobulinemia 15,5 biomedica Genes, Genomes and , RF ATM heterozygosity as a major tumor susceptibility and radio sensitivity factor in the general population 15,5 clinico assistenziale Oncology 2 Clinical , RF Novel class sparing regimens to achieve substantial CD4 gain in R5 HIV 1 infected patients undergoing salvage therapy 15,5 clinico assistenziale AS and Related Research 1172 RF Use of genistein in Alzheimer disease: from iron levels to neuronal modifications, a combined clinical and experimental approach 15,5 clinico assistenziale Brain Disorders and , GR Stroma derived SPARC critically regulates primary and secondary lymphoid tissues homeostasis and has a role in acute myeloid leukemia and lymphoma development. 15,5 biomedica Oncology 1 Basic , RF A combined multidisciplinary approach to identify new HBV resistance determinants against last generation antiviral compounds. 15,5 biomedica Infectious Diseases and Microbiology , RF An integration system for in vivo and in vitro studies: application to patients with Ovarian Cancer 15,5 clinico assistenziale Oncology 2 Clinical , GR Rare inherited disorders of HDL metabolism: from molecular diagnosis to therapeutic development 15,5 biomedica Genes, Genomes and , RF Alimentary human exposure to cadmium: intake evaluation and risk assessment 15,5 biomedica Veterinary Food Safety FOSA , GR Alterations of the resting state cortical networks: imaging biomarker for Frontotemporal Dementia. 15,5 biomedica Brain Disorders and , GR Role of morgana/chp 1 in acute leukemia onset and progression 15,5 biomedica Oncology 1 Basic ,00 Pagina 103 di 244

104 1180 GR Epigenetic therapy and Rett syndrome: a pharmacological approach 15,5 biomedica Molecular, Cellular, and Developmental Neuroscience , GR The Rorschach test in assessment of emotions and affective disorder in MS patients. 15,5 clinico assistenziale Brain Disorders and , RF ENTIFICATION AND VALATION OF MOLECULAR MARKERS OF RESPONSE TO ADJUVANT CHEMOTHERAPY IN COLORECTAL CANCER 15,5 biomedica Oncology 2 Clinical , RF Callosal agenesis: a complex brain malformation with heterogeneous genetic origin. Identification of new genes and loci through massive parallel DNA sequencing analysis in a large set of patient with corpus callosum anomalies 15,5 biomedica Genes, Genomes and , RF Gammadelta T lymphocytes in the control of HIV 1 infection and coinfections: identification of tools to improve their survival and tissue localization. 15,5 biomedica AS and Related Research , RF Progeroid syndromes: a tool to evaluate the relative contribution of bioenergetic dysfunction and DNA repair defects to aging 15,5 biomedica Biology of Development and Aging 1186 RF Variability of the platelet response to antiplatelet therapy defined by a combined functional and proteomic approach: predictive value of vascular events in patients undergoing coronary artery bypass grafting or elective percutaneous coronary intervention 15,5 biomedica Cardiovascular and , GR Immunonogenicity of Mycobacterium tuberculosis antigen PPE44 for human T lymphocytes and interaction with human dendritic cells: implications for diagnosis and vaccine development. 15,5 biomedica Infectious Diseases and Microbiology , RF From MeCP2 gene mutation to disease expression in Rett syndrome through oxidative stress: Towards a new therapeutic strategy by a molecular level reinterpretation of the natural history of a major human pervasive developmental disorder 15,5 biomedica Biobehavioral and Behavioral Processes , RF Transgenic zebrafish model to visualize proliferation in vivo. 15,5 biomedica Cell Biology ,00 Pagina 104 di 244

105 1190 RF ENTIFICATION OF THE CELLULAR AND MOLECULAR TARGETS OF THE ANTI CANCER ACTIVITY OF HIV PROTEASE INHIBITORS: THE BASIS FOR A POTENTIAL NOVEL ANTITNEOPLASTIC COMPOUND 15,5 biomedica Interdisciplinary Molecular Sciences and Training , RF Persantine In non ischemic Cardiomyopathy 15,5 clinico assistenziale Cardiovascular and , RF Identification of new heart related mirnas as tools for diagnosis and terapy of heart malformations and diseases 15,5 biomedica Cardiovascular and , RF Tailored microrna treatment of TCL1 driven lymphoproliferative disorders 15,5 biomedica Oncology 2 Clinical , GR Realization of a gene array based method for the presurgical diagnosis of thyroid nodules 15,5 biomedica Oncology 1 Basic , RF Exploitation of permissive donor recipient HLA DPB1 disparities for graft versus leukemia activity after hematopoietic stem cell transplantation 15,5 biomedica Immunology 1196 RF Redox alteration in the tumor microenvironment. Role in inflammation and tumor progression, pharmacologic modulation 15,5 biomedica Oncology 1 Basic 1197 RF Diverging molecular roles of MeCP2 and CDKL5: from partly overlapping networks to the pathogenesis of Rett syndrome and Hanefeld variant 15,5 biomedica Brain Disorders and , GR Lactic acid bacteria as "biodrugs" in human cancer prevention 15,6 biomedica Oncology 1 Basic , RF Management and control models of risk factors for food intended for neutropenic population both in hospital environment and during domiciliation period 15,67 biomedica Veterinary Food Safety FOSA , RF Novel strategies and tools for clinical translation of autologous adult cardiac stem cells therapy 15,67 biomedica Cardiovascular and 1201 GR Pilot study comparing the safety and efficacy of the use of fixed dose combination efavirenz/tenofovir/emtricitabine (Atripla ) on alternate days versus standard of care in successfully treated HIV 1 infected patients 15,75 clinico assistenziale AS and Related Research ,00 Pagina 105 di 244

106 1202 GR EFFECT OF IMMUNOMODULATORY DRUGS ON microrna EXPRESSION, MICROENVIRONMENT AND IMMUNE CELLS IN PATIENTS WITH LYMPHOPROLIFERATIVE DISEASES 15,75 clinico assistenziale Oncology 2 Clinical , GR Analysis of development and persistence of specific memory B cells after new and routine vaccinations in HIV 1 infected children and adolescents. 15,75 biomedica Immunology , GR Safe eradication of leukemic stem cells with suicide gene modified CD44v6 redirected T cells: a novel approach for adoptive immunotherapy of acute myelogenous leukemia 15,75 biomedica Oncology 2 Clinical , GR Physical Exercise Interventions in Type 2 Diabetes: Clinical and Economic Impact 15,75 clinico assistenziale Healthcare Delivery and Methodologies 1206 GR Antiviral Immune Responses in Lymph Nodes 15,75 biomedica Immunology 1207 GR Clinical prevalence and study of pathogenetic mechanisms of neurologic disorders associated with mutations of mitochondrial carrier genes 15,75 biomedica Brain Disorders and , GR Human Neural Stem Cells for the cure of Amyotrophic Lateral Sclerosis 15,75 biomedica Brain Disorders and RF Tumor Stroma Interaction in thyroid cancer: Contribution of Cell Stress 15,75 biomedica Oncology 1 Basic , , RF Characterization of immune responses against incipient neoplasia in BRCA1/BRCA2 germ line mutation carriers: possible role for cancer risk modulating immunotherapy? 15,75 biomedica Immunology , RF Intrasubtypic and intersubtypic cross reactivity as a novel approach to pandemic influenza preparedness programmes 15,75 biomedica Immunology 1212 RF A systematic immune monitoring and tumor microenvironment dissection in a combined chemo immunotherapeutic trial of melanoma patients: searching for novel predictive or surrogate biomarkers 15,75 clinico assistenziale Oncology 2 Clinical , RF A randomized controlled trial of the effectiveness of a depression screening and management program in cardiovascular care 15,75 clinico assistenziale Biobehavioral and Behavioral Processes ,00 Pagina 106 di 244

107 1214 RF Protective or seizure precipitating effects of interictal events in focal epilepsy 15,75 biomedica Brain Disorders and , RF Human Papilloma Virus Infection in HIV positive, immigrant and pregnant women: an integrated molecular and clinical approach 15,8 clinico assistenziale Oncology 1 Basic , RF Identification of oxidative stress biomarkers as surrogate outcome measures of oxygen therapy and exercise rehabilitation programs in chronic respiratory diseases. 15,84 clinico assistenziale Cardiovascular and , GR Innovative strategy of tissue regeneration in acute and chronic kidney graft dysfunction: role of endothelial progenitor cell derived microvesicles 15,84 biomedica Digestive, Kidney and Urological Systems , GR Unique processing of DNA damage in adult stem cells 15,84 biomedica Oncology 1 Basic , GR Extending the knowledge on human and animal astroviruses (Astroviridae family): identification, genetic and biological characterization of a novel astrovirus in rabbits. 15,84 biomedica Veterinary Animal Health ANHE , GR Correlations between inflammatory cytokines and haematopoietic and endothelial stem cells function in type 2 diabetes mellitus 16 biomedica Vascular and Hematology , GR Role of satellite cell mediated regeneration of muscle fibers in facioscapulohumeral muscular dystrophy 16 biomedica Biology of Development and Aging , RF Epidemiological evaluation of health status, drug prescriptions and pediatric care in a cohort of newborn followed up for 18 months. 16 clinico assistenziale Population Sciences and Epidemiology , RF Percutaneous Tibial Nerve Stimulation (PTNS) as new rehabilitative treatment for chronic pelvic pain in patients with pelvic cancer 16 clinico assistenziale Brain Disorders and , GR Pathogenetic mechanism and novel strategies to target cardiac autonomic dysfunction in aging hearts. 16 biomedica Cardiovascular and ,00 Pagina 107 di 244

108 1225 GR IMPLEMENTATION OF TWO NOVEL DEVICES FOR VESTIBULAR DIAGNOSIS, ASSESSMENT, AND TAILORED HOME BASED REHABILITATION PROGRAMS, AND CONTROLLED TRIAL OF VESTIBULAR REHABILITATION FOR CENTRAL VESTIBULAR DISORDERS. 16 clinico assistenziale Integrative, Functional, and Cognitive Neuroscience , GR Role of the endocytic machinery in cancer 16 biomedica Oncology 1 Basic , RF Effect of palmitoleic acid treatment on AMPK pathway and on CAMK4 and DCAMKL1, genes previously associated with exceptional longevity and candidates to be regulated by palmitoleate being the former in AMPK pathway and latter repressing CAMK4 induced CREB 16 biomedica Biology of Development and Aging , GR New Therapeutic Strategies Overcoming Opportunistic Infections 16 biomedica Infectious Diseases and Microbiology , RF Identification of gender related differences in oxidative stress biomarkers associated with atherosclerotic disease progression 16 clinico assistenziale Vascular and Hematology , RF Vascular ageing in the complex pathways of cardiovascular determinants of cognitive decline in older subjects 16 clinico assistenziale Biology of Development and Aging 1231 RF Silk fibroin cells delivery systems and autologous mesenchymal stem cells: innovative, non invasive treatment for intervertebral disc degeneration 16 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , RF The Williams Beuren sydrome as model to investigate the role of mirnas in genomic disorders 16 biomedica Genes, Genomes and , GR Understanding thyroid cancer genetics: new approaches for a better cure (THYGER) 16 biomedica Oncology 1 Basic , GR Primary motor cortex and brainstem plasticity in patients with Gilles de la Tourette Syndrome and Obsessive Compulsive Disorder 16 biomedica Brain Disorders and , GR RESHAL Regional Study on Health and Ageing in Lombardia 16 clinico assistenziale Population Sciences and Epidemiology ,00 Pagina 108 di 244

109 1236 GR BIG GGT CARDIO PROJECT: Set up and clinical validation of a new immunometric assay for quantification of big gamma glutamyltransferase (big GGT), an emerging biomarker for cardiovascular risk stratification. 16 biomedica Biological Chemistry and Macromolecular Biophysics , GR New diagnostic approaches for familial hyperlipidemias 16 biomedica Genes, Genomes and , RF DISTANT METASTASIS IN NODE NEGATIVE BREAST CANCERS: INVESTIGATING THE ROLE OF INFLAMMATORY RESPONSE GENES 16 biomedica Oncology 2 Clinical , GR COL4A1/COL4A2 gene mutations in patients with deep cerebral hemorrhage 16 clinico assistenziale Brain Disorders and GR Mechanisms of tumor progression from pre tumoral stem cells 16 biomedica Oncology 1 Basic , , RF EVALUATION OF THE CHEMOSENSITIZING EFFECT OF THE PLANT ALKALO VOACAMINE ON OSTEOSARCOMA AND EWING'S SARCOMA: AN IN VITRO, IN VIVO AND CLINICAL STUDY. 16 biomedica Oncology 2 Clinical 1242 GR Role of endocannabinoids signaling in remote damage after spinal cord injury. 16 biomedica Brain Disorders and , GR Role of the growth factors activin and myostatin and their related proteins in leiomyoma formation 16 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR MicroRNA 101 depletion in the brain: exploring microrna 101 as a molecular basis for Alzheimer's disease. 16 biomedica Brain Disorders and 600, GR Time Course of Platelet Activation During the Development and Progression of Type 2 Diabetes Mellitus: Validation of Platelet Biomarkers for Predicting Thrombotic Risk and Testing Novel Preventive Strategies 16 clinico assistenziale Vascular and Hematology , GR Development of a chimeric antibody targeting the matricellular protein 90K, as a novel therapeutic agent for cancer 16 biomedica Oncology 2 Clinical ,00 Pagina 109 di 244

110 GR Use of diazoxide and mtor activators for treatment of Friedreich's ataxia 16 biomedica Molecular, Cellular, and Developmental Neuroscience GR Impact of DNp63 on resistance mechanism to chemotherapy 16 biomedica Oncology 1 Basic , , GR Palmitoylethanolamide: a possible new therapeutic approach for inflammatory bowel diseases 16 biomedica Digestive, Kidney and Urological Systems , RF Biomarkers identification and validation for malignant mesothelioma: from molecular biology to clinical practice 16 biomedica Oncology 2 Clinical , GR Nucleolin mediated breast cancer diagnostics and therapy 16 biomedica Cell Biology , GR Innovative preclinical molecular imaging techniques 16 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Characterization of different human Mesodermal Stromal Cell populations: applications for regenerative medicine and bone marrow transplantation 16 biomedica Biology of Development and Aging , GR Pathway based analysis of ischemic stroke subtypes assessed by genome wide association study 16 clinico assistenziale Genes, Genomes and , RF Environmental, genetic and epigenetic factors in amyotrophic lateral sclerosis 16 biomedica Brain Disorders and , RF Siglec 7 in immune response to viral infections: a potential cellular biomarker capable of identifying the clinical stages of HIV 1 and HCV infections. 16 biomedica Immunology , RF Optimization of Tissue microarrays (TMA) technology for immunohistochemestry in colorectal cancer: development of a pre screening model for Hereditary Nonpolyposis Colorectal Cancer (HNPCC) 16 biomedica Oncology 2 Clinical , RF AGE IN DIET AND BLOOD, CARDIOVASCULAR DISEASE, CANCER AND COGNITIVE DECLINE. A POPULATION STUDY IN SOUTHERN ITALY. 16 biomedica Population Sciences and Epidemiology ,00 Pagina 110 di 244

111 1259 RF Deep inside the oxaliplatin neurotoxicity: new SOD mimetic compounds as strategy to prevent and cure neuropathy 16 biomedica Oncology 2 Clinical , RF Facioscapulohumeral muscular dystrophy: serial muscle MRI study, immunological surveillance and biomolecular characterization of affected versus unaffected muscles to define non invasive outcome measures, assess the role of inflammation and elucidate the 16 biomedica Musculoskeletal, Oral and Skin Sciences , RF Ferritin and ferritin related metals as diagnostic tools in Alzheimer's disease 16 biomedica Brain Disorders and 1262 RF Effect of Sunitinib treatment on circulating tumor cells (CTC) in metastatic renal cancer (mrcc) 16 biomedica Oncology 2 Clinical , RF The relation between neurodegeneration and inflammation in Multiple Sclerosis: NR4A2 puts a dampener on inflammation 16 biomedica Brain Disorders and , GR Establishment of a new diagnostic tool for an innovative molecular analysis of Fragile X syndrome and premutation associated diseases. 16 biomedica Genes, Genomes and , RF Setting up a new LC MS method for determination of palytoxin and ovatoxin a as an alternative method to mouse bioassay in seafood analyses 16 biomedica Interdisciplinary Molecular Sciences and Training 1266 RF MicroRNAs as novel sensitive diagnostic and prognostic biomarkers of myocardial infarction 16 clinico assistenziale Cardiovascular and , GR COMT x Dysbindin double ko mice will help humans in early detection of schizophrenia 16 biomedica Biobehavioral and Behavioral Processes , RF Host and viral factors as biomarkers of treatment outcomes in chronic B and C hepatitis 16 clinico assistenziale Infectious Diseases and Microbiology 1269 GR Small Ubiquitin like Modifier (SUMO) dependent regulation of Na+/Ca2+ exchanger (NCX) isoforms in cerebral ischemia: a strategy for identifying new targets for therapeutic intervention 16 biomedica Molecular, Cellular, and Developmental Neuroscience ,00 Pagina 111 di 244

112 1270 RF DNA Damage induced by potential new antineoplastic drugs: Role in Toxicity and Mutagenicity 16 biomedica Oncology 1 Basic , RF Efficacy of active research and access to cure promotion for tuberculosis in migrants accessing primary health centres and Roma camps. 16 clinico assistenziale Healthcare Delivery and Methodologies , GR The critical problem of Multiple Sclerosis patients troubled by spasticity who are non responders or intolerant to oral anti spastic drugs: a wide randomizedcontrolled study comparing the effect of focal muscle vibration and neuromuscular taping on gait 16 clinico assistenziale Musculoskeletal, Oral and Skin Sciences , GR Impact of myocardial 123I metaiodobenzylguanidine (mibg) imaging on patient selection and risk stratification before device therapy for heart failure. Correlation with residual myocardial viability and cost effectiveness evaluation. 16 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , GR Neurobiology of frataxin and neuroprotective effects of alpha lipoic acid and EPO in a new in vitro model of Friedreich Ataxia 16 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Feasibility study on adipose stem cells transplantation from autologous fat tissue in thoracic surgery 16 biomedica Oncology 2 Clinical , GR New methods for Non ionizing imaging and guidance of ENDOvascular devices in CArdiac Surgery (NENDOCAS) 16 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Innovative therapeutic approaches against CD49d driven microenvironmental interactions in chronic lymphocytic leukemia and multiple myeloma 16 biomedica Oncology 1 Basic , RF INDOLEAMINE 2,3 DIOXYGENASE (O) AND TRYPTOPHAN DIOXYGENASE (TDO) AS POTENTIAL TARGETS FOR THERAPEUTIC AGENTS USEFUL IN POST ISCHEMIC BRAIN DAMAGE 16 biomedica Brain Disorders and , GR PDGF receptor alpha agonists as inhibitors of melanoma growth in vivo 16 biomedica Oncology 1 Basic , GR ENTIFICATION OF RELIABLE BIOMARKERS OF DIABETIC NEPHROPATHY BY POWERFUL AND COMPLEMENTARY PROTEOMIC STRATEGIES 16 biomedica Digestive, Kidney and Urological Systems ,00 Pagina 112 di 244

113 1281 RF Development of effective cancer therapies based on functional proteomics and cancer stem cell targeting 16 biomedica Oncology 2 Clinical , RF UNDER PHOSPHORYLATED MECP2 AS A NEW THERAPEUTIC STRATEGY IN RETT SYNDROME 16 biomedica Brain Disorders and , RF FISABILITY OF A HOME BASED PALLIATIVE CARE PROGRAM FOR NON ONCOLOGIC PATIENTS 16 clinico assistenziale Healthcare Delivery and Methodologies , RF MicroRNA regulated expression of HLA G and tolerance via adaptive regulatory T cells induced by tolerogenic dendritic cells 16 biomedica Immunology 1285 RF Prion like transmission in neurodegenerative protein misfolding disorders (PRIMIS) 16 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Prevention of severe toxicity by fluoropyrimidines by screening dihydropyrimidine dehydrogenase variants. 16 biomedica Oncology 2 Clinical , RF IMMUNOTHERAPY FOR FOOD ALLERGY WITH TOLEROGENIC ALLERGEN TOOLS: PRECLINICAL STUDY IN MOUSE MODELS OF SENSITIZATION AND ANAPHYLAXIS 16 biomedica Immunology , RF The role of inflammatory network and associated brain micro and macrostructural damage in longitudinal neuropsychiatric symptom expression in patients with Mild Cognitive Impairment and early Alzheimer disease 16 biomedica Brain Disorders and , RF TOXIC EFFECTS INDUCED BY POLYAMINE METABOLITES ON MELANOMA CELLS: A NEW THERAPEUTIC APPROACH 16 biomedica Oncology 1 Basic , RF A cohort study of persons with hepatitis C and/or hepatitis B virus infections in southern and northern Italy 16 biomedica Population Sciences and Epidemiology , RF ALTERNATIVE AND RELIABLE IN VITRO METHOD FOR BONE IMPLANT BIOMATERIAL BIOCOMPATIBILITY AND OSTEOINTEGRATION 16 biomedica Veterinary Animal welfare ANWE , RF Biological Networks of host pathogens interplay in genital cancers: Determinants of Cancer Susceptibility and response to Therapy 16 biomedica Oncology 1 Basic ,00 Pagina 113 di 244

114 1293 RF The role of the association of two urinary biomarkers (PCA3mRNA and GSTP1) in the diagnosis of the prostate cancer 16 clinico assistenziale Digestive, Kidney and Urological Systems , RF Proteomic signatures as biomarkers of breast cancer risk and as predictors of outcome in women with early breast cancer. 16 biomedica Oncology 2 Clinical , RF Selective NF kappab inhibitory peptides: a first step toward novel anti cancer therapeutics 16 biomedica Oncology 2 Clinical , RF Tumor microenvironment and host immune response: characterization of new mechanisms of tumor evasion and identification of possible therapeutic targets. 16 biomedica Oncology 1 Basic , RF The separate roles of long lived plasma cells and memory B cells in protection and autoimmunity. 16 biomedica Immunology , RF HIGH THROUGHPUT DRUGS SCREENING IN CELLULAR MODELS OF OSTEOBLAST DIFFERENTIATION AND CYSTIC FIBROSIS 16 biomedica Genes, Genomes and , RF Anticancer therapies based on correcting TGFß+ associated immune dysfunctions in myeloid cells 16 biomedica Immunology , RF Multifactorial analysis of indicators of short and long term outcomes in long term mechanically ventilated patients 16 clinico assistenziale Cardiovascular and , RF Planar Cell Polarity signaling and Neural Tube Defects 16 biomedica Genes, Genomes and , GR Construction of an IL 23/p40 antagonist: study of a potential immunology target in multiple sclerosis 16,17 biomedica Immunology , RF Clinical and economical impact of advanced molecular strategies for bacterial and fungal diagnosis in oncohematological patients with suspected sepsis 16,17 clinico assistenziale Infectious Diseases and Microbiology 1304 RF Novel strategies to limit post ischemic myocardial damage: vagal nerve stimulation and stem cells therapy 16,17 biomedica Cardiovascular and 1305 RF Innovative diagnostic and prognostic biomarkers in primary systemic vasculitides 16,17 biomedica Immunology ,00 Pagina 114 di 244

115 1306 RF Genotoxic effects related to pesticide exposure in greenhouses: a novel biomonitoring approach 16,2 biomedica Oncology 1 Basic , RF PATHOPHYSIOLOGICAL EVALUATION AND THERAPEUTIC APPROACHES FOR THE NEUROLOGICAL INVOLVEMENT AFFECTING LYSOSOMAL STORAGE DISORDERS 16,25 biomedica Brain Disorders and , GR Genetic, functional and structural correlates of cognitive and emotional impairment in Mood Disorders. 16,25 biomedica Brain Disorders and , GR Disclosing LOX 1, the key receptor in endothelial dysfunction and atherosclerosis 16,25 biomedica Biological Chemistry and Macromolecular Biophysics GR Monitoring drug resistance in the canine reservoir of human leishmaniases 16,25 biomedica Infectious Diseases and Microbiology , , GR Mild Cognitive Impairment: towards a neuromodulatory cognitive rehabilitation of the memory disorder 16,25 biomedica Brain Disorders and , GR HUMAN HIPPOCAMPAL TISSUE TRANSPLANTATION AS A NOVEL STRATEGY FOR THE TREATMENT OF ALZHEIMER'S DISEASE 16,25 biomedica Brain Disorders and , GR Mother delivered infant massage as a cost effective model for early intervention in preterm infants: effects on infant brain development, mother s mental health and mother infant relationship. 16,25 clinico assistenziale Brain Disorders and , RF Aromatase inhibitors as adjuvant treatment of breast cancer 16,25 clinico assistenziale Oncology 2 Clinical RF Biomarker studies on Vitamin D and Melanoma 16,25 clinico assistenziale Oncology 2 Clinical GR Potential Therapeutic Usage Of GM1 Ganglioside In Huntington Disease (HD) 16,25 biomedica Brain Disorders and , , RF Tissue cytokine response in Leishmania infantum naturally infected dogs treated with different therapy 16,25 clinico assistenziale Veterinary Animal Health ANHE ,00 Pagina 115 di 244

116 GR Motor control in relation with visual processing in children with autism 16,25 biomedica Brain Disorders and GR Remote post conditioning as new therapeutic avenue to treat cerebral ischemia 16,25 biomedica Molecular, Cellular, and Developmental Neuroscience GR Gut microbiota and inflammatory diseases 16,25 biomedica Genes, Genomes and , , , RF Development of T regulatory cells based strategies for immunotherapy in haploidentical stem cell transplantation for patients with haematological malignancies 16,25 clinico assistenziale Oncology 2 Clinical , RF Primary prevention of Neural Tube Defects: Periconceptional Inositol supplementation of women with a previous affected pregnancy 16,25 clinico assistenziale Brain Disorders and , RF Role of micrornas in papillary thyroid carcinoma: pathways involved and possible therapeutic targets 16,25 biomedica Oncology 1 Basic , RF Hepatitis B virus in the etiology of non Hodgkin lymphoma and disease biomarkers: an Italian multicentre study 16,34 biomedica Population Sciences and Epidemiology , GR In vitro and in vivo differentiation of human amniotic epithelial stem cells into functional mature hepatocytes 16,34 biomedica Digestive, Kidney and Urological Systems , RF Proteomics of benign and malignant parathyroid tumors: mechanisms of oncogenic transformation and identification of molecular and humoral biomarkers for early diagnosis of sporadic and familial parathyroid cancer 16,34 biomedica Oncology 1 Basic , RF Inflammation, insulin resistance and cardio metabolic risk: phosphodiesterase Type 5 role in the pathophysiology of cardiometabolic diseases (from cell culture to obese and type 2 diabetic patients) 16,34 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Molecular and Cellular Analysis of GnRH 1 Neuronal Development: Implications in Hypogonadotropic Hypogonadisms 16,5 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences ,00 Pagina 116 di 244

117 1329 RF Molecular epidemiology and behavioural determinants of HAV and HCV hepatitis among men who have sex with men in some Italian metropolitan areas 16,5 clinico assistenziale Infectious Diseases and Microbiology , GR Multifunctional nanopore arrays tailored with angiogenesis inhibitors and cancer cell death ligands: an innovative hybrid nanodevice for a new effective cancer therapy. 16,5 biomedica Bioengineering Sciences and Technologies , RF Seafood safety and public health: development and validation of analytical methodologies for species identification to guarantee correct labelling of fishery products in Italy. 16,5 biomedica Veterinary Food Safety FOSA , RF Effects of metabolic conditions that modify vascular function on HDL levels and endothelial progenitor cells 16,5 biomedica Vascular and Hematology , GR Development of New Genotypic and Phenotypic Assays for the Analysis of Drug Resistance in HIV 1 Infected Patients Treated with Integrase Inhibitors. Synthesis and Evaluation of New Compounds Against HIV Resistant Variants 16,5 biomedica AS and Related Research , RF Modulation of autophagy and apoptosis in Mycobacterium tuberculosis host interaction: role of Transglutaminase type II. 16,5 biomedica Infectious Diseases and Microbiology , GR Integrated approach for the identification of peripheral biological markers for Anorexia Nervosa. 16,5 biomedica Biobehavioral and Behavioral Processes 1336 GR Dissecting the Polycomb mediated epigenetic determination of stem identity in adult stem cells 16,5 biomedica Genes, Genomes and , GR Effect of a population based public communication campaign to improving awareness and knowledge on palliative care. A quasi experimental study in the Liguria Region. 16,5 clinico assistenziale Healthcare Delivery and Methodologies , GR Towards a therapeutic anti metastatic breast cancer in a mouse model by validation of new generated drugs 16,5 biomedica Oncology 2 Clinical 1339 GR A multimodality approach to cancer cachexia. Clinical translational study to evaluate the efficacy of an oral, ambulatorial, low cost treatment approach on novel patient centred outcomes of cancer cachexia 16,5 clinico assistenziale Oncology 2 Clinical ,00 Pagina 117 di 244

118 1340 GR Tumor regression grade (TRG) and erb B2 expression in resectable carcinomas of stomach and gastro oesophageal junction after neoadjuvant chemotherapy: clinical and pathological correlations 16,5 biomedica Oncology 2 Clinical , RF Canonical Wnt signaling in CNS regeneration 16,5 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Immunogenetics of Myasthenia Gravis by genome wide association scan (GWAS) analysis 16,5 biomedica Immunology 1343 RF Inner Retinal Dysfunction of the Cone System in Inherited Photoreceptor Degenerations: A Study of Disease Sequence and Assessment of Novel Therapeutic Strategies. 16,5 clinico assistenziale Genes, Genomes and , GR Robotic therapy for the rehabilitation of lower limbs in pediatrics 16,5 biomedica Musculoskeletal, Oral and Skin Sciences GR Perceiving actions to improve their execution in brain damaged patients. 16,5 clinico assistenziale Brain Disorders and , , RF Epidemiological and toxicogenomics approaches for the evaluation of the adverse reproductive outcomes associated with airborne exposure 16,5 biomedica Genes, Genomes and 1347 RF Development of an Integrated MRI/SPECT System for Monitoring Ischemic Stroke and Stem Cell Transplantation 16,5 biomedica Emerging Technologies and Training in Neurosciences 1348 GR Amniotic fluid stem cells are involved in muscle stem cells niche repopulation 16,5 biomedica Musculoskeletal, Oral and Skin Sciences , GR Dissecting the neural basis of behavior through multimodal imaging and computational modeling of decision making in health and neuropsychiatric disorders 16,5 biomedica Biobehavioral and Behavioral Processes , RF F Fluorohymidine Positron Emission Tomography as an early predictor of response to neoadjuvant therapy in patients with locally advanced breast carcinoma 16,5 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering ,00 Pagina 118 di 244

119 1351 RF PHARMACOGENOMICS OF ANTEPRESSANT DRUGS: PHARMACOGENETIC OF SSRIs, AND THE APPROPRIATE PRESCRIPTION OF ANTEPRESSANT AGENTS IN MILD AND MODERATE MOOD DEPRESSIVE DISORDERS IN GENERAL PRACTICE, SOMATIC CO MORBITY AND COMMUNITY CARE 16,5 biomedica Genes, Genomes and , GR Generation and preclinical validation of myocardial bio substitutes fabricated with human autologous stem cells for heart mending 16,5 biomedica Cardiovascular and , GR Inhibition of human Follicular Lymphoma cells growth by a PNA specific for t(8;14) translocated bcl2 16,5 biomedica Oncology 2 Clinical , GR Characterization of epigenetic changes in mammary Stem Cells in mice subjected to excess food intake 16,5 biomedica Oncology 2 Clinical , RF Optimization of the early diagnosis of hepatic encephalopathy at a minimal stage, inquire on its clinical and biochemical correlates, educational perspectives for rehabilitation techniques. Acronym: E.D.U.C.A.T.IO.N. STUDY 16,5 clinico assistenziale Brain Disorders and , GR Use of protective cultures for the prevention and treatment of mastitis in small ruminants as an alternative to antibiotics 16,5 biomedica Veterinary Animal welfare ANWE , RF Host immune system behavior during standard of care chemotherapy in cancer patients: role of regulatory T cells in patient immune response and clinical outcome 16,5 clinico assistenziale Immunology , RF Targeting the Hodgkin Lymphoma microenvironment by CXCR4 inhibition: overcoming resistance to therapy. 16,5 biomedica Oncology 1 Basic , RF GENOMIC AND PROTEOMIC ALTERATIONS IN HUMAN HEPATOCELLULAR CARCINOMA FROM THE SOUTH OF ITALY: INSIGHTS INTO PROGNOSIS AND CLINICAL MANAGEMENT IN RELATION TO ETIOLOGY AND METABOLIC RISK FACTORS 16,5 biomedica Genes, Genomes and , RF Correlation between redox status and markers of risk and progression of melanoma 16,5 biomedica Musculoskeletal, Oral and Skin Sciences 1361 RF A clinical standardized model to fenotype COPD patients and to assess disease severity 16,5 clinico assistenziale Cardiovascular and ,00 Pagina 119 di 244

120 1362 RF Tesla vs 7 Tesla MRI comparison in the evaluation of cerebral and cerebellar cortex in healthy adults. 16,5 biomedica Bioengineering Sciences and Technologies , RF REFERENCE MODELS IN RADIOLOGICAL TECHNOLOGIES AND PRACTICES (REMORA) 16,5 clinico assistenziale Healthcare Delivery and Methodologies , RF Immunological and virological effects of maraviroc vs raltegravir vs efavirenz in combination with emcitrabin/tenofovir in the treatment of ART naïve HIVinfected patients 16,5 clinico assistenziale AS and Related Research , RF Inflammatory signaling, aging and neurodegenerative diseases: preclinical and clinical investigation 16,5 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Use of the Tat protein to develop vaccines and therapeutic interventions 16,5 biomedica AS and Related Research , RF Appropriateness of diagnosis and immunotherapy of allergic diseases: Immunochemical methods in improving mould allergenic extracts characterization and standardization. 16,5 biomedica Immunology , RF Identification of new molecular targets for the development of alternative therapeutic approaches to reduce tumor recurrence 16,5 biomedica Oncology 1 Basic , RF The neuron glia cross talk in the recruitment and function of glial cells. Role of the novel neuronal signal hyccin. 16,5 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Identification of clinically relevant fingerprints of lung cancer by a novel proteomic/peptidomic platform 16,5 biomedica Oncology 2 Clinical , RF Brain death organ donors: Improving the number and quality of organs for transplantation 16,5 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Improving the diagnosis of selected rare diseases and rare tumors: MicroRNAs as emerging biomarkers 16,5 biomedica Oncology 2 Clinical ,00 Pagina 120 di 244

121 1373 RF Innovative strategies to analyze protein drug interaction based on structural and computational methods 16,5 biomedica Biological Chemistry and Macromolecular Biophysics , GR Effects of low dose mixture of thyroid disruptors in critical phases of development: a translational approach 16,5 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Molecular mechanisms for senataxin induced motor neuron degeneration: cellular and animal models. 16,5 biomedica Brain Disorders and , RF The role of Dbl in the development of diffuse large B cell lymphoma: molecular and biologic characterization. 16,5 biomedica Oncology 1 Basic , RF Tracing of antimicrobial resistance genes in food: a tool for consumer's health risk assessment 16,5 biomedica Veterinary Food Safety FOSA , GR Role of cardiac progenitor cells in doxorubicin induced cardiomyopathy 16,5 biomedica Cardiovascular and , RF GMP implementation and pre clinical validation of cardiac stromal cells for heart repair. 16,5 biomedica Cardiovascular and , RF Regenerative medicine and biosafety: development of a microarray based screening for transformation risk of in vitro expanded cells. 16,5 biomedica Musculoskeletal, Oral and Skin Sciences , RF New approach to optimize osseointegration in dental implantology. Stem cells and regenerative therapy. 16,5 biomedica Bioengineering Sciences and Technologies , RF Unravelling the molecular basis of infection driven lymphoma 16,5 biomedica Oncology 1 Basic , RF Chikungunya virus a new emerging infection. A multidisciplinary study on virus, vector and host immune cells cross talk 16,5 biomedica Infectious Diseases and Microbiology , RF Endocrine disruptors in the food chain: occurrence in feed and food and effects in vitro of perfluorinated organic compounds and inorganic arsenic 16,5 biomedica Veterinary Food Safety FOSA Pagina 121 di 244

122 1385 GR The mother to child health flow: gene environment interactions in human placenta 16,67 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF The leader peptide of a human rec. MnSOD as molecular carrier which delivers high amounts of Cisplatin into tumor cells inducing a fast apoptosis in vitro and in vivo. 16,67 biomedica Oncology 2 Clinical , GR Deleted in Breast Cancer 1, a new player in the DNA damage response. 16,67 biomedica Oncology 1 Basic , RF Exploiting the osteogenic properties of mesenchymal stem cells for bone structural functional repair in hemodialysis patients: role of uremic toxins. 16,7 biomedica Musculoskeletal, Oral and Skin Sciences , RF Functional interactomes: spatio temporal dynamics and molecular organization of membrane receptors in cancer 16,75 biomedica Biological Chemistry and Macromolecular Biophysics , RF Epigenetics/proteomics of osteosarcoma chemoresistance predictive biomarkers and development of therapeutics. 16,75 biomedica Oncology 2 Clinical , GR A multidisciplinary approach for the identification of novel therapeutic treatments for infants and young children affected by respiratory tract infections. 16,75 biomedica Infectious Diseases and Microbiology , GR Skin Biopsy morphometry as Outcome measure for Neuropathy in Diabetes: a worldwide validation study. (The SBOND Project) 16,75 biomedica Brain Disorders and , RF Predicting and preventing cardiotoxicity in the era of breast cancer targeted therapy. Novel molecular tools for clinical issue 16,75 clinico assistenziale Oncology 2 Clinical , RF Tissue specific T and NK cells characterization for adoptive cell therapy of cutaneous and ocular melanoma 16,75 biomedica Oncology 2 Clinical , GR Thymosin Beta 4: a novel marker for prognosis and detection of colorectal cancer 16,75 clinico assistenziale Oncology 2 Clinical ,00 Pagina 122 di 244

123 1396 GR Reproductive function assessment in patients with testicular tumors after oncological treatment 16,75 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Residual tumor after preoperative chemotherapy in breast cancer as a model to study resistant micrometastatic disease 16,75 clinico assistenziale Oncology 2 Clinical , GR Role of abscisic acid (ABA) in the pathogenesis of atherosclerosis and development of anti ABA drugs. 16,75 biomedica Cardiovascular and , GR Efficacy of new antiretroviral compounds through PK/PG monitoring 16,75 clinico assistenziale Genes, Genomes and , GR Molecular characterization of the cellular players involved in the epithelialmesenchimal transition process underlying idiopathic pulmonary fibrosis. 16,75 biomedica Cardiovascular and , GR Molecular Identification of Resistance/Responsiveness Mechanisms to Anti VEGF Therapy in Breast Cancer 16,75 biomedica Oncology 2 Clinical , GR Signaling pathway profiling of renal cell carcinoma for targeted therapy 16,75 biomedica Oncology 2 Clinical GR Gastric SubMucosal Space as a new site for pancreatic islet transplantation in pigs. 16,75 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , , GR Predictive models of genito urinary and sexual dysfunction after high dose radiotherapy for prostate cancer 16,75 clinico assistenziale Oncology 2 Clinical , GR New immunogenetic parameters to predict graft versus host disease and graft rejection after allogeneic hematopoietic stem cell transplantation for inborn genetic diseases 16,75 biomedica Immunology , GR Innovative statistical approaches to identify aetiopathogenetic factors of myopia in 10 Italian genetic isolates. 16,75 biomedica Genes, Genomes and ,00 Pagina 123 di 244

124 1407 RF LIVER METABOLITE ENTIFICATION IN HEPATOCELLULAR CARCINOMA BY HIGH RESOLUTION MAGIC ANGLE SPINNING 1 H NMR SPECTROSCOPY 16,75 biomedica Oncology 2 Clinical , RF SEARCHING FOR VAL, RELIABLE AND FAST TOOLS TO DIFFERENTIATE FRESH FROM FROZEN FISH PRODUCTS 16,75 biomedica Veterinary Food Safety FOSA , RF The role of joint aspiration and intraoperative culture to isolate pathogen organism in infected total knee arthroplasty. 16,75 clinico assistenziale Infectious Diseases and Microbiology , GR Easy HIFU: simplified lesion localization for HIFU treatment 16,84 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering RF Investigation of the role of estrogen receptors in chronic lymphocytic leukemia 16,84 biomedica Oncology 1 Basic , , GR Role of Dbl in epithelial cell transformation: search for diagnostic markers and therapeutic targets for epithelial cancers. 16,84 biomedica Oncology 1 Basic , GR A systematic in vitro analysis of early molecular events involved in the amyloidogenesis. 16,84 biomedica Molecular, Cellular, and Developmental Neuroscience , GR DO ESTROGENS INFLUENCE BONE METABOLISM THROUGH THE MODUDULATION OF THE IMMUNE RESPONSE? 16,84 biomedica Musculoskeletal, Oral and Skin Sciences , GR Understanding in vivo the bio pathological role of micrornas: scientific basis for the identification of novel targets and tools for the non conventional anticancer therapy of human hepatocellular carcinoma 16,84 biomedica Oncology 1 Basic , RF Metabolomics of sebum: a new approach to investigate the pathological mechanisms underlying acne. 16,84 biomedica Musculoskeletal, Oral and Skin Sciences 1417 RF New approches to prevent or rescue antineoplastic induced cardiomyopathy: from growth factors to cardiac progenitor cell therapy 16,84 biomedica Cardiovascular and , RF Sensitivity and resistance of Ph+ leukemias to tyrosine kinase and leukemia stem cell inhibitors 17 biomedica Oncology 1 Basic ,00 Pagina 124 di 244

125 1419 GR Pro angiogenic, anti angiogenic and inflammatory signals regulating circulating endothelial colony forming cell (ECFC) migration, proliferation and differentiation: impact on lung vascular development after very premature birth 17 biomedica Cardiovascular and , RF Niche factors driving hepatic stem cell differentiation toward Hepatic Stellate/Miofibroblast Cells: novel therapeutic targets for liver fibrosis 17 biomedica Cell Biology , GR Role of P glycoprotein and Multi drug resistant 1 for the clinical management of patients HIV positive receiving transplant and treated with antiretroviral and immunosuppressant drugs. 17 biomedica AS and Related Research , GR Nuclear Pore Complex Genes: towards the Clinical translation of basic results 17 biomedica Oncology 1 Basic , GR EVALUATION OF BRAIN DEVELOPMENT IN FETUSES AND NEWBORNS WITH SEVERE CONGENITAL HEART DISEASE 17 clinico assistenziale Brain Disorders and , GR Analysis of signal transduction pathways involved in haematopoiesis, in the generation and maintenance of leukaemia cell stemness. Identification of novel diagnostic, prognostic and therapeutic targets. 17 biomedica Vascular and Hematology , GR MUSCLE IMAGING ASSESSMENT AS A GOLD STANDARD NON INVASIVE TOOL IN ADDRESSING THE DIAGNOSIS OF NEUROMUSCULAR DISORDERS 17 biomedica Musculoskeletal, Oral and Skin Sciences , RF A PROSPECTIVE GENETIC STUDY ON PULMONARY SURFACTANT CANDATE GENES AND PROTEOMIC ANALYSIS ON BALF IN A SAMPLE OF BRONCHOPULMONARY DYSPLASIA PRETERM EUROPEAN NEWBORNS 17 biomedica Cardiovascular and , RF INCENCE OF DENTAL PATHOLOGIES AND PREVENTION STRATEGY IN MENTAL RETARDATION FROM RARE PATHOLOGY 17 clinico assistenziale Risk, Prevention and Health Behavior , GR Metabolomic profiling and docosahexaenoic acid derived anti inflammatory mediators in exhaled breath condensate and sputum of adults with cystic fibrosis 17 clinico assistenziale Cardiovascular and , GR Molecular biomarkers of response to chemo immunotherapy in melanoma patients 17 biomedica Oncology 2 Clinical ,00 Pagina 125 di 244

126 1430 RF Role of the beta 2 adrenergic receptor in the clinical and molecular setup of the metabolic abnormalities of the failing heart: a positron emission tomography in small animals and humans. 17 biomedica Cardiovascular and , GR EFFICACY OF A GROUP BASED COGNITIVE BEHAVIORAL INTERVENTION FOR PEOPLE WITH SEVERE MENTAL DISORDERS A RANDOMIZED CONTROLLED TRIAL (THE 4C STUDY) 17 clinico assistenziale Biobehavioral and Behavioral Processes , RF Detection of titanium dioxide nanoparticles in food to evaluate toxicity towards humans 17 biomedica Veterinary Food Safety FOSA , RF Evaluation of DNA methylation status as new biomarker in breast cancer 17 biomedica Oncology 2 Clinical , GR A multidisciplinary approach for neurobiology of Eating Disorders: evaluation of state and trait dependent neural correlates of the core psychopathology, using a combined, MRI, fmri, and psychiatric assessment, repeated before and after a cognitive behavi 17 clinico assistenziale Biobehavioral and Behavioral Processes , GR Alcohol abuse in the adolescent brain: a gate toward addiction? 17 biomedica Molecular, Cellular, and Developmental Neuroscience RF PCSK9,plasma LDL, and Atherosclerosis 17 biomedica Cardiovascular and , , RF Effects of HIV protease inhibitors on in vitro and in vivo experimental models of human uterine cervical tumours 17 biomedica Oncology 1 Basic , GR PROGNOSTIC MODEL IN PATIENTS WITH METASTATIC RENAL CELL CANCER IN TREATMENT WITH SUNITINIB 17 clinico assistenziale Oncology 2 Clinical 1439 GR Identification of the molecular mechanisms through which the mutant p53/id4 axis controls cytokines production and angiogenesis in breast cancer 17 biomedica Oncology 1 Basic , RF Early cognitive deficit in Alzheimer Disease: segregation of conceptual network 17 clinico assistenziale Brain Disorders and ,00 Pagina 126 di 244

127 1441 RF Aberrant choline metabolism as a source of imaging biomarkers and pharmacological endpoints for targeted therapies in breast and ovary cancer 17 biomedica Oncology 1 Basic , GR Neuroprotective effects of flavocoxid in Alzheimer s disease: an in vitro and in vivo study 17 biomedica Brain Disorders and , RF New bio markers for the clinical surveillance of workers previously exposed to asbestos. 17 biomedica Oncology 2 Clinical , GR Preventing onset of synaptic degeneration in early stage of Alzheimer disease 17 biomedica Brain Disorders and , RF Advanced phylogenetic analysis in the study of molecular evolution and the surveillance of viral infection. 17 biomedica Healthcare Delivery and Methodologies , GR Circulating myeloid subset as tool to predict microenvironment composition in Hodgkin`s Lymphoma: identification of new molecular targets for anti neoplastic immunity. 17 biomedica Oncology 2 Clinical , RF Ex vivo selection, characterization and amplification of antitumor T cell lines from patients with ovarian cancer and metastatic colorectal carcinoma for adoptive immunotherapy 17 biomedica Oncology 2 Clinical , GR Membrane transporters and ion channels in chemoresistance: detection and prognostic significance in acute lymphoblastic leukemia. 17 biomedica Oncology 1 Basic , RF NONCODING RNA IN BRAIN FUNCTION 17 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Development of alternative analytical methods for the detection of irradiation treatment in poultry meat and shrimps 17 biomedica Veterinary Food Safety FOSA , GR Molecular mechanisms of RTN 1C function: role in CNS disorders. 17 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Role of lymphangiogenesis in growth, progression and metastasis of human neuroblastoma 17 biomedica Oncology 1 Basic ,00 Pagina 127 di 244

128 1453 GR ROLE OF LIVER PLASMACYTO DENDRITIC CELLS IN LIVER ISCHEMIA/REPERFUSION INJURY 17 biomedica Immunology , GR Investigating the role of Bcl 2/adenovirus E1B 19 kda interacting protein (BNip3) in mitochondrial dysfunction in Huntington's disease 17 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Critical issues of late preterm births: improving appropriateness and standard of cares 17 clinico assistenziale Healthcare Delivery and Methodologies , GR Use of stromal cells isolated from bone marrow fat (BMFC) to treat the animal model of multiple sclerosis (EAE). A preclinical study. 17 biomedica Brain Disorders and , GR Phenotype, genotype and pharmacological dissection of mtor pathway for the identification of druggable molecules in high grade osteosarcoma. 17 biomedica Oncology 1 Basic , RF MicroRNAs Gene Expression Profiling of rejection/infection in solid organ transplantation in children 17 biomedica Immunology , RF VARIATIONS IN CANCER CARE ACROSS ITALY 17 clinico assistenziale Healthcare Delivery and Methodologies , RF Study of mechanisms involved in the protective effect of physical exercise on agedependent cognitive impairment 17 biomedica Biology of Development and Aging , GR Genetic variants involved in the susceptibility to MGUS, at risk of transition to SMM and MM. 17 biomedica Oncology 1 Basic , GR Neuroinflammation and synaptic function: an electrophysiological analysis in experimental multiple sclerosis 17 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Treatment with intra erythrocyte encapsulated Dexamethasone sodiumphosphate in cystic fibrosis patients with double lung transplantation 17 clinico assistenziale Immunology , RF Circulating microrna signatures as novel noninvasive biomarkers for breast cancer 17 biomedica Oncology 2 Clinical ,00 Pagina 128 di 244

129 1465 RF Impacting on microglia behavior through mesenchymal stem cells: implications for the treatment of multiple sclerosis 17 biomedica Brain Disorders and , RF Evaluation of HIV 1 Tat protein at physiologically hypoxic conditions: impact on HIV 1 infection and immune responses 17 biomedica AS and Related Research , GR Study of HIV 1 regulatory mechanisms mediated by Tat 17 biomedica AS and Related Research , RF START STATE OF THE ART ONCOLOGY IN EUROPE A COMPREHENSIVE EVENCE BASED DATABASE ON MALIGNANT TUMOURS IN SUPPORT OF HEALTH CARE PROFESSIONALS IN DAILY ONCOLOGY PRACTICE AND PATIENT ADDRESSED INFORMATION 17 clinico assistenziale Healthcare Delivery and Methodologies , RF Neuroinflammation in Alzheimer's disease 17 biomedica Immunology , GR The role of gene profiling: tissue and circulating markers in the prediction of bone metastases in breast cancer patients 17 biomedica Oncology 2 Clinical , GR D Aspartate: an atypical amino acid with therapeutic potential in cognitive disorders 17 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Genome wide analysis (GWA) in RET wild type hereditary and sporadic medullary thyroid cancer to identify either new oncogenic alterations or chromosomal regions of interest linked to the tumoral disease 17 biomedica Genes, Genomes and , RF GEMCART: a randomized phase II trial with Carboplatinum and Gemcitabine and their combination with Trastuzumab in HER2 positive metastatic breast cancer patients pretreated with Trastuzumab and Lapatinib. 17 clinico assistenziale Oncology 2 Clinical , GR Production of human pluripotent cells by chemical reprogramming 17 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , GR High resolution pharmacogenetic profiles of genes involved in drug absorption, distribution, metabolism and elimination in adult acute lymphoblastic leukemia patients to optimize current and novel therapies 17 biomedica Genes, Genomes and ,00 Pagina 129 di 244

130 1476 GR Cutaneous squamous cell carcinoma (CSCC) and precursor lesions: role of cutaneous HPV infection, gene/protein profiling and investigation of novel prognostic markers 17 biomedica Oncology 1 Basic , GR Angiogenesis as therapeutic target in glioblastoma: study of predictive and/or prognostic tissue markers, mechanisms of action and effects. 17 clinico assistenziale Oncology 2 Clinical , GR Development of an immunological based strategy against membrane proteins involved in human cancer: a potential diagnostic and clinical application 17 biomedica Oncology 2 Clinical , GR Guided immunomodulation of stroke activated blood borne inflammatory cells as a novel therapeutic rationale to limit brain infiltration and neuronal damage in the ischemic penumbra in mammals 17 biomedica Brain Disorders and 1480 RF Definition of new immunological and biochemical biomarkers of diagnostic, prognostic and therapeutic value in the management of Kawasaki disease 17 biomedica Immunology , RF Role of lipofuscin in the pathogenesis of Alzheimer's disease 17 biomedica Brain Disorders and , RF Novel combination therapies based on Reverse Transcriptase inhibitors for cancer treatment of improved efficacy 17 biomedica Oncology 1 Basic , RF "Animal models of neuroferritinopathies: new genetic models to study the role of iron in neurodegeneration" 17 biomedica Brain Disorders and 1484 RF Neurotoxins in bladder and prostate cancer: new potential agents for chemotherapy 17 biomedica Oncology 1 Basic , RF Molecular Mechanism of Cancer Prevention: The Psoriasis Model 17 clinico assistenziale Oncology 1 Basic 1486 RF Mesenchymal cells in the hematopoietic stem cell transplantation setting: evaluation of immunomodulatory function, impact on hematopoietic recovery and on leukemic cell survival. 17 clinico assistenziale Vascular and Hematology , RF A functional genomic approach to overcome drug resistance in ovarian cancer 17 biomedica Oncology 1 Basic ,00 Pagina 130 di 244

131 1488 RF DISORDERS WITH ANOMALOUS OSSIFICATION: PROOF OF PRINCIPLE FOR NEW THERAPEUTIC APPROACHES 17 biomedica Genes, Genomes and , RF Engineering Intestinal Probiotics with IgE Moieties to Establish a Universal Fight Against Allergy 17 biomedica Digestive, Kidney and Urological Systems , RF Identification of prognostic molecular markers in Wilms tumor through genomewide approaches 17 biomedica Oncology 1 Basic , RF INHERITED THROMBOCYTOPENIAS: FROM GENES TO DRUGS THROUGH IN VITRO MODELS 17 biomedica Vascular and Hematology , RF Epithelial ovarian cancer: cancer stem cell, tumor microenvironment and in vitro response to drugs. 17 biomedica Oncology 1 Basic , RF Development of novel molecules and medical devices for the treatment of wet agerelated macular degeneration 17,17 biomedica Cell Biology 1494 GR Role of MicroRNAs and Ultraconserved Regions in the pathogenesis and treatment of Renal Cell Carcinoma 17,17 biomedica Oncology 1 Basic , RF Hepatocellular carcinoma and glioblastoma induce abnormal vascular organization: study on the role of their tumor infiltrating stromal cells. 17,17 biomedica Oncology 1 Basic , GR Emerging viral pathogens of carnivores and possible risks for human health 17,17 biomedica Veterinary Animal Health ANHE , RF TUMOR INITIATING CELLS AND THEIR MICROENVIRONMENT IN ACUTE MYELO LEUKEMIA. CHARACTERIZATION AND TARGETING 17,17 biomedica Oncology 1 Basic , RF PROJECT: Role of B cell receptor signaling in CLL: prognostic relevance and new therapeutic strategies 17,17 biomedica Oncology 1 Basic , RF Study of ADAM17/TACE as a therapeutic target in epithelial ovarian cancer 17,17 biomedica Oncology 1 Basic GR Clinical validation of an high sensitivity HIV RNA test. 17,25 biomedica AS and Related Research , ,00 Pagina 131 di 244

132 1501 GR Mesenchymal stem cells in the treatment of ALS: from bench to bedside 17,25 biomedica Brain Disorders and , GR EPEMIOLOGY OF HBV AND HCV INFECTIONS IN SICILY: MONITORING THROUGH MOLECULAR CHARACTERIZATION OF THE VIRAL STRAINS 17,25 biomedica Infectious Diseases and Microbiology , RF Feasibility and accuracy of robotic colonoscopy with minimally invasive colon preparation. 17,25 clinico assistenziale Digestive, Kidney and Urological Systems , GR Bisphosphonate related osteonecrosis of the jaws and genetic polymorphism: a genetic study 17,25 biomedica Oncology 2 Clinical , GR Multidisciplinary novel approach to early detection of atherosclerotic plaque formation and progression: analysis of new biocompatible molecular imaging probes and biomarkers 17,25 biomedica Cardiovascular and , RF Role of stress echocardiography in valvular heart disease 17,25 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , RF In vivo prognostication of posterior uveal melanoma: a combined cytogenetic and circulating tumor cells approach. 17,25 clinico assistenziale Oncology 2 Clinical , RF MOVEMENT OBSERVATION EMPOWERS NEUROPLASTIC REORGANIZATION OF MOTOR NETWORKS AND ENHANCES RECOVERY FROM STROKE 17,25 biomedica Brain Disorders and , GR THE DNA "METHYLOME" OF HUMAN CUTANEOUS MELANOMA: PROGNOSTIC, CLINICAL AND IMMUNOTHERAPEUTIC IMPLICATIONS 17,25 biomedica Oncology 2 Clinical , GR Investigation of the expression profile and role of Caveolin 1 in rhabdomyosarcoma tumors 17,25 biomedica Oncology 1 Basic , RF Early detection of lung cancer in high risk population: an integrated bio imaging and bio molecular approach 17,25 clinico assistenziale Oncology 2 Clinical , GR Double blinded, sham controlled, randomized study to evaluate the efficacy and safety of premotor cortical stimulation in focal hand dystonia 17,25 clinico assistenziale Brain Disorders and ,00 Pagina 132 di 244

133 1513 RF Pathogenic simian/human immunodeficiency virus with genetic changes after passage from rhesus to cynos: genetic pathway of transmitted /founder viruses and impact of the MHC class I in a cohort of cynomolgus monkeys. 17,25 biomedica AS and Related Research , RF New discovery approaches for the non invasive early diagnosis of lung cancer 17,25 biomedica Oncology 2 Clinical , RF MOLECULAR GENETIC AND PHENOTYPIC EXPRESSION OF MONOGENIC HYPERTRIGLYCEREMIAS 17,25 biomedica Genes, Genomes and , RF Evaluation of the immune response against human papillomavirus induced by prophylactic vaccination and after natural infection aiming to identify immune correlates of protection 17,25 clinico assistenziale Immunology , RF Non invasive prenatal diagnosis of genetic diseases by separation and enrichment of circulating fetal cells in maternal blood 17,25 biomedica Genes, Genomes and , GR Assessing short and long term comparative effectiveness of PCI vs. CABG: an observational outcome study using administrative data 17,25 clinico assistenziale Healthcare Delivery and Methodologies 1519 RF CAUSES AND CONSEQUENCES OF FETAL PROGRAMMING OF SOMATIC, KNEY, AND LIVER GROWTH AFTER BIRTH. A BIOCHEMICAL, GENETIC AND SYSTEMS BIOLOGY APPROACH AND AN ECONOMIC EVALUATION. 17,3 biomedica Biology of Development and Aging , GR Systematic assessment of the acute and chronic effects of trauma on quality of life 17,34 biomedica Integrative, Functional, and Cognitive Neuroscience GR Identifying novel genetic and molecular determinants of bone health and disease 17,34 biomedica Musculoskeletal, Oral and Skin Sciences 1522 RF Low grade inflammatory status, sleep apnea syndrome and endocrine andrologic dysfunctions in patients with morbid obesity: Role of specific profiles of circulating chemokines and type of macrophage activation sustaining chronic inflammation and its relati 17,34 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Neuroprotective activity of transmembrane chemokines CX3CL1 and CXCL16 in experimental models of brain ischemia and Parkinson disease. 17,34 biomedica Brain Disorders and Pagina 133 di 244

134 GR Evaluation of the role of oxytocin in the placebo effect 17,5 biomedica Integrative, Functional, and Cognitive Neuroscience RF Fragility and myelomatous fractures: bone quality, bone healing and therapy 17,5 clinico assistenziale Biology of Development and Aging RF Neonatal Thyroid function and phthalates exposure NeThyPhEx 17,5 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , , , GR A multidisciplinary approach to the study of Spatial Awareness in brain tumor and stroke: from a better diagnosis to the recovery/prevention of the deficits. 17,5 biomedica Brain Disorders and , GR Characterization of Circulating Tumor Cells in patients with advanced breast cancer 17,5 biomedica Oncology 2 Clinical , RF Remyelination failure in multiple sclerosis: to understand the mechanism and overcome the differentiation block of resident and newly generated oligodendrocyte precursor cells. 17,5 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Evaluation of the rough strain Brucella melitensis B115 as a vaccine against brucellosis 17,5 biomedica Veterinary Animal Health ANHE , GR Effects of in vitro nutrient supplementations on inflammation and zinc homeostasis modulation as prospective for nutrigenetic interventions in atherosclerosis and type 2 diabetes. 17,5 biomedica Vascular and Hematology 1532 GR Early non invasive diagnosis and prognostic biological profiles of bladder cancer: from laboratory to clinic 17,5 biomedica Oncology 2 Clinical , GR EXTENDING REHABILITATION FROM HOSPITAL TO HOME WITH WEARABLE DEVICES 17,5 biomedica Musculoskeletal, Oral and Skin Sciences , RF Developmental exposure to environmental toxicants and risk of Autism Spectrum Disorders: an integrated in vivo and in vitro approach to unravel the molecular mechanisms involved in the neuroendocrine and behavioral effects of organophosphorous pesticides 17,5 biomedica Integrative, Functional, and Cognitive Neuroscience ,00 Pagina 134 di 244

135 1535 GR Platelet transcriptomics and gene expression profiling as a tool to predate myocardial infarction 17,5 biomedica Cardiovascular and , GR Genetic diversity, phylogenetic analyses and phylodinamic of HCV from plasma, PBMC and liver tissue in patients of the Mediterranean area 17,5 biomedica Healthcare Delivery and Methodologies , RF Lexical semantic skills, APOE and neuroanatomical substrate of semantic memory in early diagnosis of Alzheimer's disease 17,5 clinico assistenziale Biobehavioral and Behavioral Processes , RF Characterization of the impact of co infections by hepatitis viruses on the antiviral immune response and disease progression in HIV infected individuals from Subsaharian Africa. 17,5 clinico assistenziale AS and Related Research , GR Mechanisms Of Stent Thrombosis (MOST) Study 17,5 clinico assistenziale Cardiovascular and , GR UnderstaNding the mechanisms of vitamin D Effects on muscular STrength and PerformANce in elders (UNDERSTAND) 17,5 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR RANK L/RANK OPG pathway as novel target in induced bone loss disease: from rheumatoid arthritis to osteoporosis. 17,5 clinico assistenziale Musculoskeletal, Oral and Skin Sciences , GR Identification of lung cancer associated oncoantigens as target for active immunotherapy 17,5 biomedica Immunology , GR The role of iconic memory in developmental dyslexia 17,5 biomedica Brain Disorders and , RF Carboplatin and Pemetrexed chemotherapy in malignant mesothelioma Italians patients: impact of the C1900T ERCC1 and TSER* genotype on response to chemotherapy, clinical outcome and toxicity. 17,5 clinico assistenziale Oncology 2 Clinical , GR Novel RNase based antitumor agents 17,5 biomedica Oncology 1 Basic Pagina 135 di 244

136 1546 GR Amyotrophic Lateral Sclerosis neuro muscular degeneration shares pathological features with Spinal and Bulbar Muscular Atrophy: study of the Androgen Receptor dependent machanism(s) in cellular toxicity and analysis of the possible implications of "dopin 17,5 biomedica Molecular, Cellular, and Developmental Neuroscience , GR TUMOR AND VASCULAR TARGETED THERAPIES AGAINST PEDIATRIC AND ADULT SOL CANCERS 17,5 biomedica Oncology 2 Clinical , RF SPECIFIC READING DISORDERS: EARLY ENTIFICATION AND INTERVENTION ON AT RISK CASES THROUGH INTERNET BASED, SELF PACING SYSTEMS, REMOTELY SUPERVISED 17,5 clinico assistenziale Healthcare Delivery and Methodologies , RF Wound healing and vasculogenic mimicry as players of early relapse in triple negative breast carcinomas 17,5 biomedica Oncology 1 Basic , GR Cryptic chromosomal imbalances analysis in patients with Idiopathic Generalized Epilepsy through high resolution array CGH 17,5 biomedica Brain Disorders and , RF Physician group management of chronic viral hepatitis: value index of personalized antiviral therapy 17,5 clinico assistenziale Healthcare Delivery and Methodologies 1552 RF HEALTHY SPINE: A PERSPECTIVE, RANDOMIZED, CONTROLLED, BLIND TRIAL APPLIED TO AN INTEGRATIVE APPROACH WITH BACK SCHOOL AND SHIATSU, FOR HEALTHCARE STAFF. 17,5 clinico assistenziale Healthcare Delivery and Methodologies , GR Role of astrocytic inwardly rectifying K+ channels in the pathogenesis of Autism Spectrum Disorders with susceptibility to seizures (Autism Epilepsy Phenotype). 17,5 biomedica Molecular, Cellular, and Developmental Neuroscience , RF ENTIFICATION OF NEW PREDISPOSING ALLELES IN HEREDITARY BREAST AND OVARIAN CANCER FAMILIES WITH A NON INFORMATIVE BRCA1/2 TEST 17,5 biomedica Genes, Genomes and , GR PET, serum tumour markers and circulating tumour cells in early treatment efficacy assessment for patients with advanced non small cell lung cancer (NSCLC) 17,5 clinico assistenziale Oncology 2 Clinical , RF Cancer stem cells and hematopoietic growth factors: a dangerous liaison? 17,5 biomedica Oncology 1 Basic ,00 Pagina 136 di 244

137 1557 RF Identification of biomarkers for disease prognosis and monitoring in Metachromatic Leukodystrophy (and other lysosomal storage diseases) 17,5 biomedica Brain Disorders and , RF Early use of Extracorporeal Membrane Oxygenation in ARDS (EuECMO) 17,5 clinico assistenziale Cardiovascular and , GR The impact of inflammation and multimodal neuroimaging parameters on aphasia recovery prediction in patients with acute ischemic stroke 17,5 biomedica Brain Disorders and , GR Understanding the molecular mechanisms of Heat Shock Protein 90 for the rational discovery of new anticancer molecules: From computational models to in vivo experiments 17,5 biomedica Biological Chemistry and Macromolecular Biophysics , RF Circulating tumor cells (CTC) in early mammary breast cancer 17,5 clinico assistenziale Oncology 2 Clinical , RF Role of circulating mesenchymal stem cells and strail in heart failure: a potential approach for regenerative medicine 17,5 biomedica Cardiovascular and , RF Muscle functional, structural and molecular correlates of motor disability in obese subjects with Prader Willi syndrome. 17,5 biomedica Musculoskeletal, Oral and Skin Sciences , GR Epidemiological role of Human Bocavirus in acute respiratory illnesses in Puglia. 17,5 clinico assistenziale Infectious Diseases and Microbiology , RF TOWARD PERSONALIZED MEDICINE: INVESTIGATING ANTEPRESSANT EFFICACY AND THE UNDERLYING MOLECULAR MECHANISMS IN A GENE BY ENVIRONMENT INTERACTION PERSPECTIVE 17,67 biomedica Biobehavioral and Behavioral Processes , RF Generation of disease specific RIsk Scores for heritable COnnective tissue Diseases with arterial aneurysm and dissection (RISCOD) 17,67 clinico assistenziale Cardiovascular and 1567 RF Transgenic C. elegans as a model for mechanistic studies and the development of innovative therapeutic strategies for Alzheimer disease and peripheral amyloidoses 17,67 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Targeting the heparanase/heparansulfate system for pediatric sarcoma therapy 17,67 biomedica Oncology 1 Basic ,00 Pagina 137 di 244

138 1569 RF Development of a computerized clinical chart and a set of quality indicators to monitor patients with Systemic Lupus Erythematosus (SLE) in routine clinical practice and in observational studies and development of a multicenter lupus network. 17,67 clinico assistenziale Musculoskeletal, Oral and Skin Sciences , RF BIOCHEMICAL MECHANISMS OF IMMUNOACTIVATION IN HIV INFECTED PATIENTS: THE ROLE OF TAT PROTEIN 17,67 biomedica AS and Related Research , RF DISTAL MYOPATHIES: MOLECULAR CHARACTERIZATION AND CLINICAL, HISTOPATHOLOGICAL AND MUSCLE IMAGING ASSESSMENT 17,67 biomedica Musculoskeletal, Oral and Skin Sciences , GR ASSOCIATION OF CALCA GENE POLYMORPHISMS, OXATIVE STRESS, AND ARTERIAL FUNCTION WITH MIGRAINE AND POSSIBLE TREATMENT IMPLICATIONS 17,75 biomedica Brain Disorders and , GR Immune reconstitution after nonmyeloablative allogeneic stem cells transplant and role of thymic derived donor T cells in preventing infections and promoting graft versus tumor effect. 17,75 biomedica Oncology 2 Clinical , RF Impact of cytokine blocking therapy on immunological pathways in lesional skin and systemic circulation of patients with psoriasis and psoriatic arthritis. 17,75 biomedica Immunology , GR Zoonotic parasitic infections in livestock and humans from zootechnical farms, didactic farms and agritourisms in the Salerno province, Southern Italy 17,75 biomedica Infectious Diseases and Microbiology 1576 RF Assessment of the role of image guided hypofractionated intensity modulated radiotherapy in the treatment of prostate, lung and head and neck cancers 17,75 clinico assistenziale Oncology 2 Clinical 1577 RF Development of molecular diagnostic strategies and validation of clinical application in Oncology 17,75 clinico assistenziale Oncology 2 Clinical , GR Experimental correlation amongst density, static strength and cracking behaviour of sows' bones weakened by an hormonal situation similar to that observed in post menopausal women 17,75 biomedica Bioengineering Sciences and Technologies , RF Genetic determination of dopamine signaling of cognitive phenotypes related with schizophrenia 17,75 biomedica Brain Disorders and Pagina 138 di 244

139 1580 GR Off label use of antiretroviral drugs in children exposed to HIV 1: a nation wide multicenter study 17,75 clinico assistenziale AS and Related Research , RF Identification of novel prognostic markers for Hepatitis C virus therapy by quantitative proteomics 17,75 biomedica Infectious Diseases and Microbiology , RF Treatment of high risk cervical intraepitelial neoplasia in HIV seronegative women with HIV protease inhibitors: background preparatory studies and phase II clinical trial 17,75 clinico assistenziale Oncology 2 Clinical 1583 RF GENETIC MODULATION OF COELIAC DISEASE 17,75 clinico assistenziale Genes, Genomes and , RF Development of multitargeted therapy and identification of predictive biomarkers for the optimization of colorectal cancer treatment: a comprehensive approach combining molecular, functional and prognostic information 17,75 biomedica Oncology 2 Clinical , RF Improving RAAS Blockers prescription on the basis of pharmacoepidemiological and laboratory data 17,84 clinico assistenziale Vascular and Hematology , GR Isolation of pluripotent stem cells from murine and human testes for generation of autologous spermatozoa 18 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences 394, GR Targeting specific steps of cholesterol biosynthesis to inhibit angiogenesis and tumor progression 18 biomedica Oncology 1 Basic 1588 GR Evaluation of virus specific T cell response in patients with occult heptitis B virus infection undergoing immunosoppressive chemotherapy: potential implications for clinical management. 18 biomedica Immunology , RF Evaluation of the impact of a Menopausal Women s Health Clinic Network in Chronic Disease Prevention 18 clinico assistenziale Population Sciences and Epidemiology , GR Inflammatory stage in post operatory patients measured by microdialysis. 18 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering ,00 Pagina 139 di 244

140 1591 GR GLUTEN ANTAGONIST PEPTES AS A NEW THERAPEUTIC STRATEGY IN CELIAC DISEASE 18 biomedica Digestive, Kidney and Urological Systems , GR Neuroprotection and modulation of endogenous neurogenesis: role of Neuropeptide Y and estrogens in an in vivo model of hippocampal neurodegeneration. 18 biomedica Brain Disorders and , GR MRI and EEG EMG markers for the diagnosis and prognosis in young onset torsion dystonia 18 clinico assistenziale Brain Disorders and , RF Evaluation of benefit/risk profile of different antineoplastic regimens administered to elderly cancer patients with advanced stage tumor and polipathology to simplify medical interventions. 18 clinico assistenziale Oncology 2 Clinical , RF The role of micrornas in T cell physiology and neoplastic transformation. 18 biomedica Immunology , RF DIAGNOSTIC, CLINICAL AND GENETIC CORRELATES OF ENDOPHENOTYPES IN ANOREXIA NERVOSA: COGNITION AND NEURAL CONNECTIVITY 18 clinico assistenziale Brain Disorders and , RF A translational approach to the oxidative stress burden in end stage renal disease 18 clinico assistenziale Population Sciences and Epidemiology GR Brain and ketogenic diets: unsuspected potentialities during aging 18 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences 1599 RF In vitro and ex vivo studies of Electromagnetic Fields' effects on stem cells and risk assessment of health care workers 18 biomedica Healthcare Delivery and Methodologies , GR Targeted chemotherapy for osteosarcoma: biointegrated nanoparticles as a forthcoming therapeutic strategy 18 biomedica Oncology 2 Clinical , GR Experimental studies and preclinical applications of stem cells from amniotic fluid: new perspectives for the treatment of neurological and orthopedic diseases. 18 biomedica Cell Biology , RF Suppression of epitope spreading with inhibitors of PARP 1 and its relevance to treatment of multiple sclerosis 18 biomedica Brain Disorders and ,00 Pagina 140 di 244

141 1603 GR CONDITIONAL MOUSE MODELS FOR THE STUDY OF THE WNT/BETA CATENIN PATHWAY IN CEREBELLAR DEVELOPMENT AND MEDULLOBLASTOMA FORMATION 18 biomedica Biology of Development and Aging , RF Transplant of Placenta Derived Cells as a Potential Anti proliferative treatment in animal models of cancer 18 biomedica Oncology 2 Clinical , RF Evaluation of the antiviral role of Immunogenic Complexes in woodchucks with chronic WHV infection. Analysis of virological and immunological correlates for identifying new therapeutic strategies for HBV chronic liver disease 18 biomedica Infectious Diseases and Microbiology , GR Exploring the role of the Na+/Ca+2 exchanger in the dysregulation of oligodendrocyte differentiation to establish new therapeutic strategies to control demyelination and astrogliosis in Multiple Sclerosis and other demyelinating diseases 18 biomedica Molecular, Cellular, and Developmental Neuroscience , RF REHABILITATION OF VISUAL AND SPATIAL DISORDERS THROUGH MULTISENSORY AND TRANSCRANIAL DIRECT CURRENT STIMULATION 18 clinico assistenziale Integrative, Functional, and Cognitive Neuroscience , RF Defining the rational basis for an epigenetic therapy of malignant gliomas: the role of histone H3 lysine 27 methylation 18 biomedica Oncology 1 Basic , GR Inside the proteins and their interactomes: a reverse proteomic approach to define protein functions in Apicomplexan parasites and identify novel potential drug targets. 18 biomedica Infectious Diseases and Microbiology , GR Role of phospholipid scramblase 1 in immunogenic cancer cell death. 18 biomedica Oncology 1 Basic , GR Metabolic disruption: molecular mechanisms, detection and clinical implications in human health 18 biomedica Biological Chemistry and Macromolecular Biophysics , RF INNOVATIVE THERAPEUTIC STRATEGIES AND PROGNOSTIC FACTORS IN UNDIFFERENTIATED THYRO CARCINOMA 18 biomedica Oncology 1 Basic , GR Lipid specific CD1 restricted T cell response in the pathogenesis of Crohn's Disease 18 biomedica Immunology ,00 Pagina 141 di 244

142 1614 RF How chronic infections contribute to progression of aging: from immune activation to telomere shortening and cellular senescence 18 clinico assistenziale Biology of Development and Aging , GR Metabolically normal and metabolically abnormal obesity: effects of overfeeding 18 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Understanding mitochondrial function in podocyte signaling to dissect podocyte damage in idiopathic nephrotic syndrome 18 biomedica Digestive, Kidney and Urological Systems , GR DESIGN AND TEST OF A SPECIFIC CUSTOM ARRAY CGH FOR GENOME WE COPY NUMBER VARIATIONS (CNVs) ANALYSIS IN HYPERTROPHIC CARDIOMYOPATHY 18 biomedica Genes, Genomes and , RF Mechanisms and early biomarkers of cardiovascular complications and graft failure in liver transplant recipients 18 biomedica Cardiovascular and , GR Testing the effectiveness of an intensive and comprehensive drug abuse preventive program through wastewater analysis, a novel approach to estimate drug consumption in a whole community. 18 clinico assistenziale Risk, Prevention and Health Behavior , GR An in vivo model to study molecular determinants in T ALL. 18 biomedica Oncology 1 Basic , GR Brain metabolism and cognitive training in mild Alzheimer's Disease: exploring the neurobiological substrate of a novel cognitive intervention program 18 clinico assistenziale Brain Disorders and , RF Information Communication Technology resources in a model of care based on the integration between hospital and local health and social services 18 clinico assistenziale Healthcare Delivery and Methodologies , GR Mitochondrial Citrate Carrier: a new target for chemotherapeutics in cancer therapy 18 biomedica Oncology 1 Basic , RF Definition of a cluster of biomarkers representative of healthy ocular surface and predictive of a pathological ocular surface manifestations: a simply method to classify inflammation. 18 biomedica Brain Disorders and Pagina 142 di 244

143 1625 GR Tumor associated macrophages and thyroid hormone system in the pathophysiology of tumors 18 biomedica Oncology 1 Basic , RF Synergistic antibiotic combinations for multidrug resistant nonfermentative gramnegative bacilli (Ps. aeruginosa, A.baumannii) causing severe nosocomial infections 18 clinico assistenziale Infectious Diseases and Microbiology , GR Amplitude integrated EEG (aeeg) and General Movements (GMs) as early indicators of neurodevelopmental outcome in preterm 18 clinico assistenziale Brain Disorders and , GR The expression and cellular localization of BCRP are affected by EGFR pathway in NSCLC: role of erlotinib and analysis of microrna in the search of novel pharmacogenomics biomarkers of drug resistance 18 biomedica Oncology 1 Basic , GR Vectors as indicators of infectious diseases in wildlife, livestock and humans: early surveillance by metagenomics for emerging animal infectious diseases and zoonoses. 18 biomedica Infectious Diseases and Microbiology , GR Search for novel disease genes by whole exome sequencing in patients affected by neurocristopathies and without mutations in known predisposing genes. 18 biomedica Genes, Genomes and , GR Arrhythmogenicity of Diesel Exhaust Nanoparticles in Healthy and Failing Hearts: Focus on Mechanisms 18 biomedica Cardiovascular and , GR New chemical entities targeting human gamma delta T cells to improve tuberculosis therapy: from basic science to clinical approaches 18 biomedica Immunology 1633 GR From new genes to new therapeutic strategies in Frontotemporal Lobar Degeneration and Alzheimer Disease 18 clinico assistenziale Brain Disorders and , RF Effect of parathyroidectomy and Vitamin D3 supplementation on vertebral fractures and other non classical features (quality of life, neuropsychological aspects, lipids and glucose metabolism, indexes of cardiovascular damages) of primary hyperparathyroidi 18 clinico assistenziale Oncology 2 Clinical , RF PREDICTION AND PREVENTION OF FALLS IN SUBJECTS SUFFERING FROM NEUROLOGICAL DISEASES 18 clinico assistenziale Risk, Prevention and Health Behavior ,00 Pagina 143 di 244

144 1636 GR Acid sphingomyelinase in host and tumour interaction: pathways and novel therapeutic targets 18 biomedica Oncology 1 Basic , RF micrornas AS POTENTIAL PROGNOSTIC AND THERAPEUTIC TOOLS IN MULTIPLE OSTEOCHONDROMAS DISEASE 18 biomedica Musculoskeletal, Oral and Skin Sciences , RF Antineoplastic activity of PPARalpha agonists in aggressive follicular and medullary thyroid cancers 18 biomedica Oncology 2 Clinical , RF Study of gene mutations associated with phenotypic drug resistance in multidrugresistant (MDR) and extensively drug resistant (XDR) clinical strains of Mycobacterium tuberculosis 18 biomedica Infectious Diseases and Microbiology , RF Pain in orthopedic post surgical rehabilitation: occurrence, influence and basis for development and testing of a reasoned pain free therapeutic algorithm. 18 clinico assistenziale Healthcare Delivery and Methodologies , RF Analysis of Xenotropic Murine Leukemia Virus Related Virus and Human Papillomavirus infection in Italian prostate cancer patients related with RNASEL germline variants 18 biomedica Oncology 1 Basic , RF ELF INDUCED MATURATION AND DIFFERENTIATION OF HUMAN CARDIAC STEM CELLS AND THEIR IMPLANTATION IN NUDE MICE: A PRECLINICAL STUDY FOR TREATING HEART ATTACKS 18 biomedica Cell Biology 1643 RF CRYOpreservation and in vitro maturation of human oocytes by using new antioxidant formulations against ROS production (acronym: CRYOROS) 18 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences 1644 RF New therapeutical strategies in head and neck squamous cell carcinoma based on the use of histone deacetylase inhibitors 18 biomedica Oncology 1 Basic , GR The epileptogenic malformed brain: pathogenic mechanisms of epilepsy and new therapeutic strategies 18 biomedica Brain Disorders and , RF Study on the interaction among activated fibroblasts, liver cells and ductular epithelium in cirrhosis and hepatic neoplasia. 18 biomedica Oncology 1 Basic Pagina 144 di 244

145 1647 RF Development of a p190 derived vaccine as immune target therapy for the control of minimal residual disease in Ph+ acute lymphoblastic leukemia patients. 18 clinico assistenziale Oncology 2 Clinical , RF Altered choline metabolism in ovarian cancer. Integration and interpretation of multilevel data for the validation of the significance of choline kinase activity and expression in prognosis and/or therapeutic guidance 18 biomedica Oncology 2 Clinical , RF Cardiovascular Immunology Ontology: Reasoning to identify novel candidate genes for cardiovascular diseases 18 biomedica Bioengineering Sciences and Technologies , RF Congenital Anomalies of the Urinary Tract: Validation of Functional MR urography (MRU) as unique diagnostic step in children and development of new sequences (DWI, DTI and BOLD imaging) for the assessment of renal dysplasia. 18 biomedica Bioengineering Sciences and Technologies , RF Effects of PLP1 gene overexpression 18 biomedica Genes, Genomes and RF Survivors of Suicide Italian Trial (SoS IT) 18 clinico assistenziale Biobehavioral and Behavioral Processes RF Role of Bv8/prokineticin 2 and its receptors PKR1 and PKR2 in psoriasis 18 biomedica Musculoskeletal, Oral and Skin Sciences , , , RF NOVEL OUTCOME MEASURES AND NATURAL HISTORY IN CHARCOT MARIE TOOTH DISEASE 18 clinico assistenziale Brain Disorders and , RF A multidisciplinary approach to identify molecular determinants of Triple Negative Breast Cancer 18 biomedica Oncology 2 Clinical , GR PERFUSION IMAGING STUDIES OF PANCREATIC DUCTAL ADENOCARCINOMA 18 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Isolation of new molecules for the cure of retinal dystrophies 18 biomedica Cell Biology , RF Mineralocorticoid Receptor and human adipocyte: regulation of adipose differentiation, expansion and pro inflammatory capacity in visceral epicardial versus subcutaneous adipose depots 18 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences ,00 Pagina 145 di 244

146 1659 RF Identification and characterization of glioblastoma cancer stem cells in a marker independent manner. 18 biomedica Oncology 1 Basic , RF CLINICAL AND NEUROIMAGING PREDICTORS OF COGNITIVE IMPAIRMENT AFTER STROKE 18 clinico assistenziale Brain Disorders and , RF Idiopathic pulmonary fibrosis: evaluation of biological mechanisms and identification of therapeutic targets in patients and animal models 18 biomedica Cardiovascular and , RF Unveiling neural, genetic and cognitive endophenotypes in a new model for Anorexia Nervosa: towards an individually tailored treatment. 18 clinico assistenziale Brain Disorders and , RF Identification of new markers of early renal dysfunction in type 2 diabetes 18 biomedica Risk, Prevention and Health Behavior , RF Genome based in silico identification and functional validation of novel Mycobacterium tuberculosis antigens that activate polyfunctional CD8 T cell responses in human tuberculosis 18 biomedica Immunology , GR POLYMORPHISMS of INNATE IMMUNITY GENES in HEPATOCARCINOMA 18 biomedica Genes, Genomes and , RF Molecular studies of glucosamine derivatives aimed to find new drugs with chondroprotective activity. 18,17 biomedica Musculoskeletal, Oral and Skin Sciences , GR Brain multi parametric magnetic resonance study of patients with vegetative and minimally conscious state 18,17 clinico assistenziale Brain Disorders and , GR How many cancer deaths were avoidable in Italy during ? 18,25 clinico assistenziale Healthcare Delivery and Methodologies , RF AZIB: Antitumor activity of Zoledronate in metastatic breast cancer patients: a phase II randomized study 18,25 clinico assistenziale Oncology 2 Clinical , RF Role of metabotropic glutamate receptors and calcium in spinocerebellar ataxia 1 (SCA1) 18,25 biomedica Molecular, Cellular, and Developmental Neuroscience ,00 Pagina 146 di 244

147 1671 RF Fatigue relief in Multiple Sclerosis by transcranial Direct Current neuro Stimulation (tdcs). [FaMuSNeT] 18,25 clinico assistenziale Brain Disorders and , RF The Surgical Management of Primary Tumors of the Spine 18,25 clinico assistenziale Oncology 2 Clinical , GR New approaches with nanoparticles in ex vivo human model of colon rectum cancer (CRC) for imaging and therapeutic applications. 18,25 biomedica Bioengineering Sciences and Technologies , GR SNOW ON HEART PROJECT: Magnetic resonance imaging for diagnosis of subclinical cardiotoxicity of cocaine abuse 18,25 clinico assistenziale Cardiovascular and , RF MULTI STRUCTURED DATA ANALYSIS FOR PATIENT SPECIFIC MODELLING OF HUMAN LIGAMENTS 18,25 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , GR From ciliary protein networks to epigenetic mechanisms: developing novel in vitro strategies to study primary cilia related neural defects. 18,25 biomedica Molecular, Cellular, and Developmental Neuroscience , RF alpha7 nicotinic receptor: a common target for lung cancer and Alzheimer' s disease treatment? 18,25 biomedica Oncology 2 Clinical , RF Novel techniques for administration and tracking of human Mesenchymal Stem Cells in an experimental model of Parkinson's Disease: biological and therapeutic clues leading to clinical application 18,25 biomedica Brain Disorders and , RF Multicenter study on the mechanisms related to vessel atherosclerosis in systemic rheumatic diseases as a model of accelerated atherosclerotic damage. 18,3 biomedica Vascular and Hematology , RF Ecological approach to the study of interspecies transmission of influenza A viruses 18,3 biomedica Veterinary Animal Health ANHE 1681 RF A translational medicine research collaboration to fight pre eclampsia: from molecular pathogenesis to biomarkers of the disease and novel treatments 18,34 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences ,00 Pagina 147 di 244

148 1682 GR Identification of micrornas as potential targets for innovative anti cancer therapy 18,34 biomedica Oncology 1 Basic , GR Mapping of human DNA replication origins and study of their regulation in normal and cancer cells 18,34 biomedica Oncology 1 Basic , RF Functional Imaging and Biomarkers as predictors of outcome in Head and Neck cancer patients after surgery or chemo/radiotherapy 18,34 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , GR Targeted magnetic iron oxide nanoparticles as contrast agents of magnetic resonance imaging of amyloid plaques in Alzheimer s disease 18,34 biomedica Bioengineering Sciences and Technologies , GR Involvement of kinin kallikrein system in hypertension associated with IgA nephropathy: effects on renal aquaporins 18,34 biomedica Digestive, Kidney and Urological Systems , RF APPROACHES TO IMPROVE OUTCOMES OF PANCREATIC ISLETS TRANSPLANTATION IN TYPE 1 DIABETES. ENTIFICATION OF MECHANISMS AND PREVENTION OF INFLAMMATION AS A CAUSE OF REDUCED SURVIVAL OF TRANSPLANTED ISLETS 18,34 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Characterisation of MxA and the immune infiltrates status in human renal cell carcinoma: possible utilization as prognostic markers. 18,5 clinico assistenziale Oncology 1 Basic , RF Pharmacological targeting of type 3 metabotropic glutamate receptors on cancer stem cells: an innovative anti cancer therapeutic strategy 18,5 biomedica Oncology 1 Basic , GR GENISTEIN AGLYCONE AND METABOLIC SYNDROME IN POSTMENOPAUSAL WOMEN: MECHANISMS OF ACTION AN IN VITRO MODEL AND EVALUATION OF EFFICACY ON SOME PREDICTORS OF CARDIOVASCULAR RISK IN A DOUBLE BLIND RANDOMIZED CONTROLLED TRIAL 18,5 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR CORTICAL MICROMALFORMATIONS, BIOCHEMICAL ABNORMALITIES, AND NEURAL NETWORKS IN SPECIFIC LANGUAGE DISORDER AND DEVELOPMENTAL COORDINATIONS DISORDER: A 3 TESLA MORPHOLOGICAL, SPECTROSCOPY, AND FUNCTIONAL STUDY 18,5 clinico assistenziale Brain Disorders and 203,80 Pagina 148 di 244

149 1692 RF BIOMECOLECULAR PROFILING OF NORMAL AND CANCER EPITHELIAL STEM CELLS OF THE HUMAN PROSTATE 18,5 biomedica Oncology 1 Basic , RF PAPILLOMAVIRUS (HPV) AND TELOMERE/TELOMERASE INTERPLAY IN HEAD & NECK AND ANAL CANCERS: CORRELATION WITH PROGNOSIS AND RESPONSE TO THERAPIES 18,5 biomedica Oncology 2 Clinical , GR THE BCL 2 POST TRANSCRIPTIONAL OPERON AS TARGET OF MOLECULAR CANCER THERAPEUTICS 18,5 biomedica Oncology 1 Basic , RF Morphologic venous anomalies in patients with multiple sclerosis: a case control study 18,5 clinico assistenziale Brain Disorders and , RF Predictors of response to neoadjuvant chemotherapy in advanced colorectal cancer with liver resectable disease: an observational study 18,5 clinico assistenziale Oncology 2 Clinical , RF An Integrative Approach to Identify Functional Biomarkers in Human Astroglial brain tumours: the ' omics' strategy 18,5 biomedica Brain Disorders and , GR Prostate cancer in the elderly: biological bases and development of a multi marker strategy for diagnosis and prognosis 18,5 biomedica Biology of Development and Aging , RF CREATING A NETWORK FOR THE PROVINCE OF PAVIA TO ROUND CARE OF PATIENTS WITH ALS 18,5 clinico assistenziale Healthcare Delivery and Methodologies , RF PATHOGENIC MECHANISMS OF POMPE DISEASE (GLYCOGENOSIS TYPE II): CLINICAL AND EXPERIMENTAL INTEGRATED APPROACH 18,5 biomedica Genes, Genomes and , GR Study of human exposure to dioxins in selected populations living in Campania by measuring the internal dose and selected blood protein biomarkers for the evaluation of dose response relationship 18,5 biomedica Oncology 2 Clinical , RF Retargeting of citokine induced killer (CIK) cells with bispecific antibodies or molecularly engrafted T cell receptors (TCR): a preclinical study 18,5 biomedica Oncology 2 Clinical ,00 Pagina 149 di 244

150 1703 RF Antiretroviral therapy as a preventive strategy of sexual and vertical transmission of HIV. An analysis of HIV compartimentalization in the genital secretions and in maternal breast milk: viral replication, genetic diversity, viral resistance, and local p 18,5 biomedica AS and Related Research , RF Unrevealing prognostic and therapeutic role of Poly(ADP ribose)polymerase 1 (PARP 1) in squamous cell carcinomas of the head and neck region. 18,5 biomedica Oncology 2 Clinical , GR Genetic background of glucose homeostasis. Insulin sensitivity and ß cell function across the spectra of fasting glucose and glucose tolerance in youth. 18,5 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Role of hepatitis C in atherosclerosis development 18,5 biomedica Infectious Diseases and Microbiology , GR The impact of neuroligin inactivation by in utero electroporation: correlations with autistic like behavior in rats 18,5 biomedica Brain Disorders and , GR Non invasive brain stimulation with transcranial magnetic and direct current stimulation (TMS/tDCS) in vegetative and minimal conscious state patients 18,5 clinico assistenziale Brain Disorders and , GR Functional, physical and clinical interactions of menin and parafibromin 18,5 biomedica Oncology 1 Basic RF The last contact with a health professional before suicide: What was missed? 18,5 clinico assistenziale Risk, Prevention and Health Behavior GR Development of a new fast chemosensitivity test for human colorectal cancer 18,5 biomedica Oncology 1 Basic , , , GR Involvement of hypothalamic pituitaryadrenal axis dysregulation in amyotrophic lateral sclerosis murine model: a possible therapy with an oligodeoxynucleotide antisense versus endogenous pro opiomelanocortin mrna. 18,5 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Quality Control in the Early Secretory Pathway and its role in Folding and Storage Disorders 18,5 biomedica Cell Biology ,00 Pagina 150 di 244

151 1714 RF Heterogeneity in the prevalence of risk factors for cardiovascular disease and type 2 diabetes in OBese patients and the impact of Insulin Resistance (OBIR) 18,5 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Cellular, Molecular and Serological Approaches to Characterize the Immunopathogenesis and to Identify New Diagnostic and Prognostic Markers in ACS. A Window on New Therapeutic Targets. 18,5 biomedica Vascular and Hematology , GR Role of DNA Damage Response signaling in differentiation, cell death and degeneration of human neural stem cell 18,5 biomedica Molecular, Cellular, and Developmental Neuroscience , GR SUMOylation of JNK3 as a new target for neuroprotection in neuropathology 18,5 biomedica Brain Disorders and , RF Macrophage response to pathogens in HIV 1 infected individuals: role of Nef protein in supporting opportunistic infections 18,5 biomedica AS and Related Research , GR Definition of neurometabolic biomarkers of Alzheimer s disease using H magnetic resonance spectroscopy 18,5 clinico assistenziale Brain Disorders and , GR Early detection of psychosis in children and adolescents: An evaluation of current at risk criteria 18,5 clinico assistenziale Biobehavioral and Behavioral Processes , RF Linking cell function and metabolism in T regulatory cells: implications for multiple sclerosis. 18,5 biomedica Brain Disorders and , RF In vivo IL 23 and IL 27 anti tumor activity against pediatric acute leukemia initiating cells and blast cells 18,5 biomedica Oncology 2 Clinical , GR High field MR evaluation of brain activity in low level consciousness patients 18,5 clinico assistenziale Brain Disorders and , RF Minocycline intensification in HIV infected patients with persistent virologic suppression during HAART: a pilot longitudinal clinical trial 18,5 clinico assistenziale AS and Related Research ,00 Pagina 151 di 244

152 1725 RF Crucial factors for effectiveness of a multicomponent prevention program for Disruptive Disorders in school age youths: genetic structure, psychopathological traits, psychosocial factors, and timing. 18,5 clinico assistenziale Risk, Prevention and Health Behavior , RF Towards controlling paratuberculosis in cattle through marker assisted or genomic selection 18,5 biomedica Veterinary Animal Health ANHE , RF An innovative, VLP based biotechnological platform for the development of CTL vaccines against viral diseases and tumors 18,5 biomedica Immunology , RF Epigenetic changes in myelodysplastic syndromes: role of methylation and demethylating drugs 18,5 clinico assistenziale Oncology 2 Clinical , RF EVALUATION OF COMBINED GENE AND CELL BASED APPROACHES USING NEURAL AND HEMATOPOIETIC STEM CELLS FOR THE TREATMENT OF LYSOSOMAL STORAGE DISORDERS. 18,5 biomedica Brain Disorders and , RF PRECLINICAL VALATION OF ABC TRANSPORTERS AND PROTEIN KINASES IN OSTEOSARCOMA TO OVERCOME DRUG RESISTANCE AND TO ENTIFY NEW CANDATE THERAPEUTIC MARKERS 18,5 biomedica Oncology 2 Clinical , RF Clonorchis and Opisthorchis in fish for human consumptions and in definitive hosts as dogs, cats and humans in the Campania region, southern Italy 18,6 biomedica Infectious Diseases and Microbiology 1732 RF Aquaculture diet based and post stroke patient: biodisponibility of polyunsaturated fatty acids in omega 3 enriched diets catered to patients under neuro rehabilitation and assessment of food safety risk factors 18,67 biomedica Veterinary Food Safety FOSA , GR Epigenetic Regulation of Inositide Signaling Pathways in Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML) 18,67 biomedica Cell Biology , GR Study on clock genes of ruminants in health and disease 18,67 biomedica Veterinary Animal Health ANHE RF Foxp3 and metastatic spread 18,67 biomedica Oncology 1 Basic , ,00 Pagina 152 di 244

153 1736 RF Effects of quercetin, a naturally occurring phytochemical, in enhancing apoptosis in chronic lymphocytic leukemia (acronym: PhytoCancer) 18,67 biomedica Oncology 2 Clinical , RF Relationship between endotoxin levels, immune activation and anti Tat antibodies in sera of HIV infected asymptomatic individuals 18,7 clinico assistenziale AS and Related Research , GR Development of network based molecular signature as a tool for more efficient cancer care in NSCLC 18,75 biomedica Oncology 2 Clinical , GR Clinical usefulness and prognostic value of mesothelin and other bio markers in patients with Malignant Pleural Mesothelioma 18,75 biomedica Oncology 2 Clinical , RF Haploinsufficiency of LETM1 and mitochondrial dysfunction in Wolf Hirschhorn syndrome: structural and functional analysis of mitochondria in lymphoblasts, fibroblasts and myoblasts of patients and rescue analysis in vitro 18,75 biomedica Genes, Genomes and , GR Multidisciplinary approach for the characterization of molecular determinants in Gastrointestinal Stromal Tumors. 18,75 biomedica Oncology 1 Basic , RF New clinical procedures in dental caries prevention 18,75 clinico assistenziale Healthcare Delivery and Methodologies 1743 RF Pancreatic endocrine tumours: from gene expression evidences to potential novel prognostic factors and therapeutic targets 18,75 clinico assistenziale Oncology 2 Clinical , RF Identification and characterization of biological targets for HCC therapy 18,75 biomedica Oncology 2 Clinical GR Prospective and integrative memory in dementia 18,75 biomedica Brain Disorders and , , GR LONG TERM MORBITY OF MULTIVISCERAL RESECTION FOR RETROPERITONEAL SARCOMA. A PROSPECTIVE LONGITUDINAL STUDY OF NEUROLOGICAL IMPAIRMENT AND CHRONIC PAIN 18,75 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Genetic and phenotypic characterisation of Clostridium difficile of human and animal origin to investigate on the extent of a potential zoonosis 18,8 biomedica Veterinary Animal Health ANHE ,00 Pagina 153 di 244

154 1748 GR Genetic control of the adult neurogenesis and its application in post stroke regenerative therapies 18,84 biomedica Molecular, Cellular, and Developmental Neuroscience , GR The NGR/isoDGR motif: a molecular timer for regulating endothelial cells adhesion to fibronectin and a tool for drug development 18,84 biomedica Oncology 1 Basic , GR Design and development of solid state breath analyzers for non invasive measurement of markers in the human breath, finalized to applications in the monitoring and control of patients with neurological disorders. 18,84 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Cellular therapy to rescue diabetic complications in the BioBreading rat model of type 1 diabetes 18,84 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF INTEGRATED APPROACH TO EVALUATE BIOLOGICAL EFFECTS ON LUNG, CARDIOVASCULAR SYSTEM AND SKIN OF OCCUPATIONAL EXPOSURE TO NANOMATERIALS (NanO I LuCaS) 18,84 biomedica Bioengineering Sciences and Technologies , RF Swine colostrum embedded chitosan based prosthesis: Replacement time and remodelling with autologous tissue induced by bioactive molecules for hollow organs reconstructive surgery (Te.col.pro project) 18,84 biomedica Bioengineering Sciences and Technologies , RF Dissecting the role of osteopontin in mammary carcinogenesis, from primary tumor to metastasis, toward targeted therapy. 18,84 biomedica Oncology 1 Basic , RF MALIGNANT MESOTHELIOMA. ROLE OF INFLAMMATION IN TUMOUR PROGRESSION UNDER HYPOXIC CONDITIONS: ENTIFICATION OF NEW MARKERS AND THERAPEUTIC TARGETS 19 biomedica Oncology 1 Basic , GR Cancer stem cell profiling in gastric cancer patients 19 biomedica Oncology 2 Clinical , GR The development of a tissue engineered prosthesis using decellularized blood vessels and autologous mesenchymal stem cells 19 biomedica Cardiovascular and , RF New molecular profiles for the diagnosis of colorectal pre neoplastic and neoplastic lesions 19 biomedica Oncology 1 Basic Pagina 154 di 244

155 1759 RF Innovative strategies to control HPV associated lesions: delivery of E7 oncoprotein by integrase negative lentivirus derived vectors and biodegradable polymers associated with chemotherapy; Evaluation of micrornas as therapeutic agents and targets for the 19 biomedica Oncology 2 Clinical , GR Development of multi mycotoxins screening methods for control activities of food and feed products 19 biomedica Interdisciplinary Molecular Sciences and Training , RF MODULATION OF DRUG RESISTANCE IN BRAIN TUMORS 19 biomedica Oncology 1 Basic , RF Bevacizumab in the intrahepatic arterial treatment of Hepatocellular carcinoma nor responsive to other therapies Pilot study of feasibility and safety 19 biomedica Oncology 2 Clinical 1763 GR TERMINAL CANCER PATIENTS' NEEDS EVALUTATION AS A BRGE IN COMMUNICATION BETWEEN CANCER PATIENTS, CAREGIVERS AND PROFESSIONALS 19 clinico assistenziale Healthcare Delivery and Methodologies , GR IL 1beta secretion by monocytes from healthy donors and patients with autoinflammatory diseases. Definition of mechanisms controlling processing and secretion, search for novel therapeutic strategies 19 biomedica Immunology , RF Genetic epidemiological study of the role of alterations in the mismatch repair genes in sporadic and familial endometrial and colorectal cancer in the population of the Alpine region 19 clinico assistenziale Genes, Genomes and , RF Sequential Chemotherapy with GEMOX and dual isotopes Peptide Receptors Radionuclide Therapy in the treatment of advanced stage metastatic Neuro Endocrine Tumours 19 clinico assistenziale Oncology 1 Basic , GR Investigation on genetic resistance factors to bovine brucellosis in the apulian cattle population serologically positive 19 biomedica Genes, Genomes and , GR An epizootiological survey of bat populations in the Italian peninsula by a widerange virological diagnostic protocol: implications for public health and biological conservation 19 biomedica Veterinary Animal Health ANHE ,00 Pagina 155 di 244

156 1769 RF Innovative Tool for Unicompartimental Knee Prostheses: Clinical Guidelines 19 clinico assistenziale Healthcare Delivery and Methodologies , RF Effects of a controlled combined aerobic and anaerobic training vs aerobic training on quality of life, risk profile and on the achievement of sustained metabolic control in cardiac patients with comorbid type II diabetes. 19 clinico assistenziale Cardiovascular and , RF Applicability, economic analysis and further insight into the psychoneuroendocrine mechanisms of a structured clinical and educational model (Group Care). 19 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Observatory for the Treatment of Chronic Hepatitis C Virus Infection in Italian Children 19 clinico assistenziale Digestive, Kidney and Urological Systems 1773 RF Identification, validation and development of analytical methods to detect shellfishes (mollusc and crustacean) traces in foods 19 biomedica Veterinary Food Safety FOSA 1774 RF Development of a real time monitoring "cockpit" to improve the safety managment in a health facility 19 clinico assistenziale Healthcare Delivery and Methodologies , RF Feasibility, implementation and effectiveness of a multielement intervention for first episode psychotic patients treated in Italian community mental health services. A 2 year follow up study 19 clinico assistenziale Biobehavioral and Behavioral Processes 1776 GR Use of Hiv protease inhibitors to block cervical cancer progression and recurrence in HIV uninfected women 19 biomedica Oncology 1 Basic , GR Inflammation and colorectal cancer: the hypothesis of an inflammatory niche for the maintenance of a staminal phenotype 19 biomedica Oncology 1 Basic , GR Epigenetic remodelling of NCX1 gene by a specific histone deacetylase (HDAC) to identify a new drug targets to prevent or reduce the neuronal damage in brain ischemia 19 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Molecular and functional analysis of CCMs genes in CCM (cerebral cavernous angiomas) patients: an expression study and clinical applications. 19 biomedica Genes, Genomes and ,00 Pagina 156 di 244

157 1780 RF Role of PI3Kgamma in oxidative stress induced cerebral damage following ischemia reperfusion 19 biomedica Brain Disorders and , GR Evaluating array comparative genome hybridization (acgh) for clinical genetic testing in Autism Spectrum Disorders 19 biomedica Genes, Genomes and , GR MicroPET preclinical development of novel peptidomimetic integrin inhibitors as innovative anticancer therapeutics in metastatic malignant melanoma 19 biomedica Oncology 2 Clinical , RF Validation of a novel rehabilitative tool for upper limb motor disorders based on implicit motor imagery 19 clinico assistenziale Musculoskeletal, Oral and Skin Sciences , GR Non coding RNA profiling to predict drug resistance in high risk neuroblastomas 19 biomedica Oncology 1 Basic , RF Proteomics strategies for the detection of illicit treatments on cattle: research of functional molecular biomarkers for food safety control. 19 biomedica Veterinary Food Safety FOSA , GR Characterization and Isolation of Cancer Stem Cells (CSCs) in Hepatocellular and Cholangiocellular Carcinoma and their Adaptation to Hypoxia. 19 biomedica Oncology 1 Basic , GR AN ITALIAN PROSPECTIVE STUDY ON PERSONALITY DISORDERS 19 biomedica Genes, Genomes and , GR Adverse drug reactions related to anti tuberculosis therapy: clinical, pharmacogenomic and pharmacokinetic observational case control study 19 clinico assistenziale Genes, Genomes and , GR A kidney transplant study to assess the impact of the kidney on brain injury and stroke, in spontaneously hypertensive stroke prone rats 19 biomedica Brain Disorders and , RF GENOMIC AND PROTEOMIC BIOMARKERS FOR AUTISM SPECTRUM DISORDERS 19 biomedica Brain Disorders and , RF UNDERSTANDING BASIC MECHANISMS OF ROBOT MEDIATED NEURO REHABILITATION FOLLOWING STROKE: CLINICAL AND ANIMAL STUDIES 19 biomedica Brain Disorders and , GR Novel strategy to improve anti tumor immune response: use of a tumorassociated antigen coupled with a TLR7 agonist 19 biomedica Oncology 2 Clinical ,00 Pagina 157 di 244

158 1793 GR Identification of possible molecular targets for development of new biological approaches in the therapy of juvenile idiopathic arthritis. 19 biomedica Immunology , GR USEFULNESS OF BRAIN PARENCHYMA SONOGRAPHY IN EARLY DIAGNOSIS OF EXTRAPIRAMAL SYNDROMES AND IN THE DIFFERENTIAL DIAGNOSIS BETWEEN IOPATHIC PARKINSON DISEASE AND ATYPICAL PARKINSONISMS 19 clinico assistenziale Brain Disorders and 0, GR Infliximab induced modulation of systemic and mucosal immunity in patients with inflammatory bowel diseases. 19 biomedica Digestive, Kidney and Urological Systems , RF Multifunctional Nanoengineered Capsules for Imaging and Early diagnostic and Therapy of Breast Cancer. 19 biomedica Bioengineering Sciences and Technologies , RF microrna and acute myeloid leukemia 19 biomedica Oncology 1 Basic , GR REliable markers of cardiac remodeling in left ventricular Assist device: focus on C Type Natriuretic peptide [REACTioN study] 19 biomedica Cardiovascular and , GR Study of the complex interplay among chronic cerebrospinal venous insufficiency, oxidative stress and cerebral Fe overload in MS patients 19 biomedica Brain Disorders and , GR EFFECT OF TOOLS IMPLEMENTING ADHERENCE TO MEDITERRANEAN DIET AND PHYSICAL ACTIVITY IN GROUPS OF SUBJECTS AT DIFFERENT LEVELS OF RISK FOR CARDIOVASCULAR DISEASES: FROM PREVENTION TO GENOMIC AND METABOLOMIC 19 biomedica Risk, Prevention and Health Behavior , GR Intracoronary administration of bone marrow derived mononuclear cells in ischaemic heart failure: influence of patient related and cell related factors on clinical success 19 biomedica Cardiovascular and , GR GENETIC PREDISPOSITION TO RITONAVIR ASSOCIATED LIPODYSTROPHY 19 biomedica AS and Related Research , RF Validation of Immunological Biomarkers for the Diagnosis and Cure of Diabetic Retinopathy 19 biomedica Cell Biology Pagina 158 di 244

159 1804 GR Detection of Neovascularization in Atherosclerotic Lesions by Ultrasound Molecular Imaging. A Feasibility and Pathophysiological Study. 19 biomedica Interdisciplinary Molecular Sciences and Training , RF Development of branched peptides as novel selective theranostic molecules for personalized cancer treatment 19 biomedica Oncology 2 Clinical , GR Investigation of Hepatitis E strains in wild animals population. Evaluation of zoonotic potential, implementation of new diagnostic assays, and molecular characterization. 19 biomedica Veterinary Animal Health ANHE , RF Evaluation of Influenza A virus growth and oncolytic properties in human pancreatic tumour cells and animal models 19 biomedica Veterinary Animal Health ANHE 1808 RF Pharmacogenomics of clopidogrel in acute coronary syndromes. 19 clinico assistenziale Cardiovascular and , RF Evaluation of innovative immunomagnetic concentration and development of multiplex Real Time PCR methods for detecting and monitoring pathogenic human viruses (HAV, Norovirus GGI and GGII) in vegetables and soft fruit: correlation with human cases 19 biomedica Veterinary Food Safety FOSA , RF Role of Ataxia Telangiectasia Mutated kinase in the modulation of protein stability and autophagy 19 biomedica Cell Biology , RF Widening p53 and EGFR co players in light of targeted treatments in head and neck squamous cell carcinoma. 19 biomedica Oncology 1 Basic , RF Endogenous retroelements in prostate cancer: an investigation of their role in cancer associated mutation, carcinogenesis and as candidate targets in anti cancer therapy 19 biomedica Genes, Genomes and 1813 RF THE STEMNESS AND EPITHELIAL TO MESENCHYMAL TRANSITION IN BREAST CANCER: ENTIFICATION OF NEW MOLECULAR DETERMINATS 19 biomedica Oncology 1 Basic , RF Robotic assisted locomotion training in children affected by Cerebral Palsy (CP): comparison between different rehabilitation approaches and quantitative/instrumental evaluation. 19 clinico assistenziale Musculoskeletal, Oral and Skin Sciences ,00 Pagina 159 di 244

160 1815 RF Characterization of UL14 gene in herpesvirus isolates from Water Buffalo (Bubalus bubalis) in Campania Region: its role in viral neurovirulence and impact on vaccination strategy. 19 biomedica Veterinary Animal Health ANHE , RF Autoimmunity in rare diseases: from a network supported by an advanced IT system to diagnosis, natural history, research and care in Aicardi Goutières syndrome with application to other autoimmune disorders 19 clinico assistenziale Brain Disorders and , RF Development and clinical experimentationof a low cost telerehabilitation framework based on kinematic and electromyographic biofeedback techniques 19,17 clinico assistenziale Bioengineering Sciences and Technologies , RF TTV and related anellovirus: a new surrogate marker for ensuring food safety 19,17 biomedica Veterinary Food Safety FOSA RF Discovery and validation of methylation based biomarkers for breast cancer. 19,17 biomedica Oncology 1 Basic , RF Phase I protocol for the treatment of patients affected by unresectable grade II IV gliomas overexperessing somatostatin receptors with a combination therapy of sistemic temozolamide ad intratumoral 90Y DOTATOC 19,17 biomedica Oncology 2 Clinical , RF Reduction of atherogenic and carcinogenic risks in milk and beef consumers by increasing the content of n 3 polyunsaturated fatty acids (PUFA) and conjugated linoleic acid (CLA) in milk and meat by feeding ruminants' diets with supplements rich in rumen p 19,25 biomedica Veterinary Animal welfare ANWE , GR Investigational study of T cell immune synapse impairment induced by ALL and AML tumor cells and of the potential reverting activity of lenalidomide azacitidine combinations 19,25 biomedica Oncology 2 Clinical , GR Assessment and management of craniofacial predisposing factors for sleep disordered breathing and sleep bruxism in a pediatric orthodontic population. 19,25 clinico assistenziale Musculoskeletal, Oral and Skin Sciences , GR Alkaline sphingomyelinase: A novel potential diagnostic and prognostic molecular marker for inflammatory bowel disease and colorectal cancer 19,25 biomedica Oncology 2 Clinical , RF Combined active and passive ErbB2 based immunotherapy in breast cancer patients with low expression of antigen 19,25 clinico assistenziale Oncology 2 Clinical ,00 Pagina 160 di 244

161 1826 GR Biomarkers of adverse neuropsychological outcomes in preterm newborns: Structural/functional connectivity Magnetic Resonance Imaging (MRI) and Magnetoencephalography (MEG) 19,25 biomedica Brain Disorders and , GR Study of the mechanisms involved in radiation induced brain injury: evaluation of microenvironment changes in relation to the radiation quality 19,25 biomedica Oncology 2 Clinical , GR A PROJECT IN SICILY TO RAISE DONKEY'S MILK DRINK/FOOD OF THE THIRD MILLENNIUM. IN VITRO STUDIES ON INTESTINAL AND ORAL MUCOSA CULTURES ABOUT THE TOXICITY OF DONKEY'S MILK, AND IN VIVO STUDIES ON PAEDIATRIC PATIENTS WITH ALLERGY TO COW'S MILK AND INTOLER 19,25 biomedica Veterinary Food Safety FOSA , RF TRAINING WITH SLOW BREATHING IN HEART FAILURE: A NON INVASIVE METHOD TO INCREASE THE CHOLINERGIC ANTI INFLAMMATORY PATHWAY 19,25 clinico assistenziale Cardiovascular and , RF Identification of targets for therapeutic intervention in lung cancer in never smokers through sequencing of the trascriptome 19,25 biomedica Oncology 1 Basic , RF Enteric pathogens infection risk in cancer patients and their relatives: infections prevalence, incidence and molecular epidemiology; hospital and domestic environmental hygiene; preventive and educational programs 19,25 biomedica Population Sciences and Epidemiology , GR VALATION OF A BLOOD SCREENING TEST FOR EARLY DIAGNOSIS OF PRION DISEASES IN HUMANS 19,25 biomedica Brain Disorders and , RF Cerebellar abnormalities, neuromuscular and developmental disorders: a clinical, hystopathological and genetic study 19,25 clinico assistenziale Brain Disorders and 1834 GR EFFECTS OF IMPLANTED BONE MARROW DERIVED MESENCHYMAL STEM CELLS ON ANAL SPHINCTERS INJURIES: PERSPECTIVES FOR TREATMENT OF ANAL INCONTINENCE 19,34 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Surgical Treatment of Musculoskeletal Tumours localized in the Pelvic Region: The Technological Support given by Computer Assisted Surgery 19,34 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering ,00 Pagina 161 di 244

162 1836 RF Impact of lifestyle factors on cancer outcomes and their interactions with tumor characteristics and therapies 19,34 biomedica Population Sciences and Epidemiology , RF Verocytotoxin producing Escherichia coli (VTEC) O157: identification of bacterial and host factors involved in cattle colonisation and influencing the shedding of the pathogen. 19,34 biomedica Infectious Diseases and Microbiology , GR STUDY ON THE EXPRESSION OF THE hmena PROTEIN IN PSORIASIS 19,5 biomedica Musculoskeletal, Oral and Skin Sciences GR Harnessing reactive oxygen species to target cancer cells 19,5 biomedica Oncology 1 Basic , , GR New therapeutical strategy for stroke: rational design and synthesis of peptidomimetic compounds based on molecular determinants that activate sodium calcium exchanger in the central nervous system 19,5 biomedica Brain Disorders and , RF Genetic epidemiology of Multiple Endocrine Neoplasia Type 1 syndrome in Italy: MEN1 3'UTR sequencing test and haplotype analysis at 11q13 in a large Italian series of sporadic and familial MEN1 cases 19,5 biomedica Genes, Genomes and , RF Use of natural terpenoid based products for Legionella control in hospital hotwater distribution systems. Toxicological assessment of the active principle and its antimicrobial efficacy in comparison with two conventional disinfection treatments (chlorin 19,5 clinico assistenziale Infectious Diseases and Microbiology , RF Advanced Glycated End products (AGE) and deglycating enzymes in AGEing 19,5 biomedica Biology of Development and Aging , RF The common marmoset (Callithrix jacchus) as a model for anxiety disorders: An integration of different diagnostic methodologies with transferability to the clinics 19,5 biomedica Biobehavioral and Behavioral Processes , RF PLC beta2 in breast cancer: a possible role in determining malignant cell features 19,5 biomedica Oncology 1 Basic , GR Combined effects of two peroxisome proliferator activated receptor gamma (PPAR gamma) agonists in the early phases of diabetic retinopathy 19,5 biomedica Cell Biology ,00 Pagina 162 di 244

163 1847 RF Evaluation of Mycobacterium bovis/mycobacterium caprae contamination of cattle and buffalo milk in bovine tuberculosis outbreaks 19,5 biomedica Veterinary Food Safety FOSA , RF Early Quantitative Image Based Prediction of efficacy of antiangiogenic drug treatment, in metastatic cancer patients using Dynamic Contrast Enhanced Ultrasound 19,5 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , GR Identification of genetic factors predisposing to non syndromic cleft lip with or without cleft palate (CL/P) 19,5 biomedica Genes, Genomes and , GR Semantics at rest and Autism 19,5 biomedica Brain Disorders and , GR Appropriateness and safety of drugs prescription in elderly: a new application of text mining 19,5 clinico assistenziale Risk, Prevention and Health Behavior , GR EXPANSION OF THE LIVING DONOR KNEY TRANSPLANTATION PROGRAM: HYPERIMMUNE RECIPIENTS AND AB0 INCOMPATIBLE TRANSPLANTATION 19,5 clinico assistenziale Immunology , GR Practical application for Real Time Microchip PCR: pilot study for routine monitoring of allele frequency differences of MC1R variants across population 19,5 biomedica Bioengineering Sciences and Technologies , RF Is levodopa really toxic? An electrophysiological and morphological investigation on mammalian substantia nigra dopaminergic neurons 19,5 biomedica Brain Disorders and , RF Markers of sensitivity to specific antitumor agents in HER2 Positive and Triple Negative Breast Cancer 19,5 clinico assistenziale Oncology 2 Clinical , RF Neuroimaging study of cerebral reorganization induced by robot mediated therapy in children with hemiparesis 19,5 biomedica Brain Disorders and , GR The unawareness of illness and executive dysfunction in bipolar outpatients 19,5 clinico assistenziale Biobehavioral and Behavioral Processes , GR Immunity and disability in multiple sclerosis: investigating the possible correlations between circulating CD4+ and CD8+ T cell functions and measures of disability in Multiple Sclerosis, in order to identify new markers of disability. 19,5 biomedica Brain Disorders and ,00 Pagina 163 di 244

164 1859 GR Stop Bleeding. A multicenter randomized controlled study with active control, aimed at analyzing the impact of two different transfusion strategies on hospital mortality, consumption of packed red cells and the development of coagulopathy in trauma patie 19,5 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering 1860 RF Pathological and molecular characterization of screen detected and interval colorectal cancers in Italian Colorectal Cancer Screening Programmes 19,5 clinico assistenziale Oncology 2 Clinical , GR Impact of Obesity on Cardiovascular Disease: Role of Adipokines, Inflammation and Oxidative Stress 19,5 clinico assistenziale Cardiovascular and , GR Development of Graph Theoretical Measures for the Evaluation of Brain Functional Networks from EEG signals Application to Motor Recovery through Brain Computer Interfaces 19,5 biomedica Emerging Technologies and Training in Neurosciences , GR Assessment of the clinical relevance of CDKN2A Unclassified Variants (UVs) in familial malignant melanoma/pancreatic cancer syndrome by functional and structural analyses 19,5 biomedica Genes, Genomes and , GR Mechanisms and Pattern of High Grade Glioma Diffusion. Definition of a Prevision Model and Radiobiologic Analysis for a New Irradiation Strategy 19,5 clinico assistenziale Oncology 2 Clinical , RF Peptide receptor radionuclide therapy with 177Lu DOTATATE in resistant/refractory Diffuse Large B cell NHL 19,5 clinico assistenziale Oncology 2 Clinical , GR Role of Msy 3/Csda in developmental transitions occurring in muscle maturation, innervation and degeneration 19,5 biomedica Musculoskeletal, Oral and Skin Sciences , RF SEROLOGICAL MARKERS AND ADVERSE CARDIOVASCULAR EVENTS: CONSTITUTION OF A TISSUE AND PLASMA BANK TO INVESTIGATE THEIR ROLE IN ETHIOPATHOGENESIS AND PREVENTION OF ATHEROSCLEROTIC VULNERABLE AND UNSTABLE PLAQUE 19,5 biomedica Vascular and Hematology , GR LATE THROMBOSIS IN DRUG ELUTING CORONARY STENTS: NOVEL STRATEGIES TO EVALUATE STRUT NEO ENDOTHELIALISATION 19,5 biomedica Cardiovascular and , RF Influence of detection of a refractive defect in children with attention deficit hyperactivity disorder in a treatment without stimulants. 19,5 clinico assistenziale Risk, Prevention and Health Behavior ,78 Pagina 164 di 244

165 1870 RF Thoracoscopic da Vinci Robot assisted extended thymectomy in myasthenia gravis 19,5 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering 1871 RF Evaluation of metallothionein expression, oxidative stress and inflammation in blood as possible markers for progression of alcoholic liver disease 19,5 biomedica Digestive, Kidney and Urological Systems , RF CONTROL OF TUBERCULOSIS IN THE WATER BUFFALO BY GENETIC SELECTION AND VACCINE PRODUCTION 19,5 biomedica Veterinary Animal Health ANHE 1873 RF Exploring the molecular and cellular bases of developmental disconnection in autism: probing the role of micrornas and axonogenesis 19,5 biomedica Brain Disorders and 1874 RF Strategies to reach self sufficiency for anti tetanus and anti hepatitis B hyperimmune plasma in Italy: impact on public health 19,5 clinico assistenziale Healthcare Delivery and Methodologies , RF EFFECTS OF UNHEALTHY LIFESTYLES ON BONE METABOLISM, HEALING CAPABILITY, IMPLANT OSTEOINTEGRATION RATE. 19,5 biomedica Musculoskeletal, Oral and Skin Sciences , RF Platelet Activation and Endothelial Dysfunction in Type 2 Diabetic Patients with Stable Coronary Artery Disease: Insight into Pathophysiological Mechanisms by Comparative Genomics and Proteomics 19,5 biomedica Vascular and Hematology , RF Novel approaches to cure type 1 diabetes: induction of tolerance toward transplanted pancreatic islets with third party human umbilical cord mesenchymal stem cell lines engineered to enhance their immunosuppressive potency and allow non invasive traceabil 19,5 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Molecular tools for the epidemiological surveillance of V. parahaemolyticus: Multilocus sequence typing approach 19,5 biomedica Veterinary Food Safety FOSA , GR New perspectives in diagnosis of atherosclerosis and vascular proliferative disorders with the support of cutting edge technologies. 19,67 biomedica Cardiovascular and , RF Anti idiotypic network to anti transglutaminase antibodies in the pathogenesis of celiac disease 19,67 biomedica Immunology ,00 Pagina 165 di 244

166 1881 RF Role of the interaction between reelin and sex steroids in neurobehavioural alterations isomorphic to Autism Spectrum Disorders 19,67 biomedica Brain Disorders and , GR Genetic and epigenetic determinants in familial late onset degenerative dementia 19,75 biomedica Brain Disorders and 1883 GR Reducing 1 year mortality in coronary artery bypass grafting with volatile anesthetic agents. A multicentre randomized controlled study. 19,75 clinico assistenziale Cardiovascular and 1884 GR Genotyping approach for the discovery of possible genetic biomarkers related to diet (Zinc) gene interaction and frailty in old age 19,75 biomedica Genes, Genomes and 1885 GR In vitro and in vivo study on the effects of transcranial stimulation on cerebral ischemia: from basic mechanisms to clinical application 19,75 clinico assistenziale Integrative, Functional, and Cognitive Neuroscience , GR Structural and biochemical characterization of new HIV Env/Tat molecular complexes 19,75 biomedica AS and Related Research , GR The stressed synapse. The synaptic action of acute behavioural stress and the protective effect of psychiatric drugs 19,75 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Investigation of structural and functional correlates of cognitive fatigue in Multiple Sclerosis patients using fmri and MRS 19,75 clinico assistenziale Brain Disorders and , RF Abdominal Aortic Aneurysms (AAA): a multidisciplinary fluid dynamic and metabolic investigation of rupture risk and possible rupture site 19,75 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , RF ResHomING: Innovative technology of Respiratory Home MonitorING in COPD patients 19,75 clinico assistenziale Cardiovascular and , RF INTEGRATED HOME CARE FOR NON SELF SUFFICIENT ELDERLY PEOPLE: EFFECTIVENESS AND COST EFFECTIVENESS SOLUTIONS 19,84 clinico assistenziale Healthcare Delivery and Methodologies , RF VALATION OF BAG3 PROTEIN AS A MARKER OF CARDIOVASCULAR DISEASE 19,84 clinico assistenziale Cardiovascular and ,00 Pagina 166 di 244

167 1893 GR In vivo xenograft models as a powerful tool for lung cancer pharmacogenomic profiling 19,84 biomedica Oncology 2 Clinical , GR A sirna screen to identify novel genes synthetically lethal with Chk1 as strategy for targeted cancer therapy 19,84 biomedica Oncology 1 Basic , RF Seeking an appropriate treatment for the cardiovascular diseases of Emergency Department patients: are they related to medications, smart drugs or congenital abnormalities? 19,84 clinico assistenziale Risk, Prevention and Health Behavior , GR Study of association between chronic autoimmune thyroiditis and polycystic ovary syndrome 19,84 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Systemic and local effect of inflammation on the obese phenotype 19,84 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Study of the antibiotic resistance of foodborne bacteria and the relative risk for public health 19,84 biomedica Veterinary Food Safety FOSA , RF DISAGE in Italy: Disability and Ageing Survey in Italy 20 clinico assistenziale Population Sciences and Epidemiology , GR A comprehensive strategy to eradicate prion diseases from the Italian sheep and goat populations 20 biomedica Veterinary Animal Health ANHE , RF Effect of metabolic modulation of cardiac metabolism in patients with ischemic chronic heart failure and left ventricular dysfunction 20 clinico assistenziale Cardiovascular and , RF A new preclinical model of bone metastasis from human sarcoma and carcinoma. Evaluation of new therapeutic approaches 20 biomedica Oncology 1 Basic , RF Characterization of long pentraxin PTX3 as genetic biomarker of susceptibility to endothelial dysfunction diseases: atherosclerosis and preeclampsia 20 biomedica Genes, Genomes and ,00 Pagina 167 di 244

168 1904 GR Expression defects of the RET proto oncogene as a novel mechanism underlying Hirschsprung disease 20 biomedica Genes, Genomes and , RF Increased severity of repiratory viral infections in the elderly: identification of thiol levels as biomarker and therapeutic target. 20 biomedica Infectious Diseases and Microbiology 1906 GR Molecular characterization of the Apical Membrane Antigen 1 from Italian strains of Babesia bigemina and study of its role in the protective host immune response. 20 biomedica Veterinary Animal Health ANHE 1907 GR Correlation between clinical pathological features and gene expression profile in pediatric tumors of glial origin 20 biomedica Oncology 1 Basic , RF Ribonomic approach to the development of a RNA based therapy for the Multiple Endocrine Neoplasia type 1 syndrome 20 biomedica Oncology 1 Basic , RF Leukocyte Telomere Length and telomerase gene variants: new diagnostic/prognostic markers of cardiovascular diseases? 20 biomedica Cardiovascular and , RF FUSION BETWEEN TUMOR CELLS AND NORMAL CELLS, OR TUMOR CELLS THEMSELVES CONTRIBUTES TO TUMOR INITIATION AND PHENOTYPIC EVOLUTION DURING CANCER PROGRESSION 20 biomedica Oncology 1 Basic , GR Anti neuropeptide autoantibodies and nutritional changes in Alzheimer's disease and vascular dementia: a novel approach to investigate disease mechanisms. 20 biomedica Brain Disorders and , RF GENOME WE LINKAGE ANALYSIS OF MANDIBULAR PROGNATHISM IN ITALIAN FAMILIES: A MULTICENTER TRIAL 20 clinico assistenziale Genes, Genomes and , GR Role of the COP9 signalosome in cancer progression 20 biomedica Cell Biology , GR NEW STRATEGY TO REPAIR ACUTE NEURODEGENERATIVE DISEASE by IMPLEMENTATION OF NEUROGENESIS AND GLIOGENESIS Mechanisms VIA THE PURINERGIC SYSTEM. 20 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Organized cervical cancer screening programs in Italian areas covered by population cancer registries: evaluation of outcomes and identification of critical points 20 clinico assistenziale Population Sciences and Epidemiology ,00 Pagina 168 di 244

169 GR The Impact of Cortical Pathology on the Recover after a Multiple Sclerosis Relapse 20 clinico assistenziale Brain Disorders and GR MicroRNAs: potential targets for melanoma therapy. 20 biomedica Oncology 1 Basic , , GR SATB1 as a novel marker of metastasis and chromosomal rearrangement in thyroid carcinoma 20 biomedica Oncology 1 Basic , GR ONCOGENE INDUCED PROMOTION OF A PRO TUMORAL INFLAMMATORY MICROENVIRONMENT IN PAPILLARY THYRO CARCINOMAS 20 biomedica Oncology 1 Basic , RF A cross over study of comparison between the traditional management model and the co management model of surgical patients: a new skilled role of specialist in internal medicine 20 clinico assistenziale Healthcare Delivery and Methodologies , GR Heart failure after "successful" primary percutaneous coronary intervention (PCI) for Acute Myocardial Infarction (HF AMI) 20 biomedica Cardiovascular and , GR Incremental value of 64 slice computed tomography in patients with acute myocardial infarction and without significant coronary stenosis 20 clinico assistenziale Cardiovascular and , RF Epidemiology of motor coordination disorder: screening in an unselected school population. 20 clinico assistenziale Biobehavioral and Behavioral Processes , RF TREATMENT AND COURSE OF BIPOLAR DISORDERS. PSYCHOEDUCATION, RISK FACTORS, PREVENTION OF RELAPSES AND ENDOPHENOTYPES 20 clinico assistenziale Biobehavioral and Behavioral Processes 1925 GR Role of the MYH9 locus in kidney diseases 20 biomedica Digestive, Kidney and Urological Systems , GR The Role of the Sensorimotor Cortex in Higher Cognitive Processing: clinical and therapeutic potential applications. 20 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , GR Low back pain in healthcare workers. Biomechanical analysis and rehabilitation program (LOBAP) 20 clinico assistenziale Healthcare Delivery and Methodologies ,00 Pagina 169 di 244

170 1928 GR Brain Heart biochemical crosstalking for understanding of the neurobiological bases of depression in patients with myocardial infarction: a clue for new therapeutical strategies 20 biomedica Biobehavioral and Behavioral Processes , GR Field and laboratory studies on sand flies and transmissible viruses in Italy 20 biomedica Infectious Diseases and Microbiology , GR The role of dopamine and endocannabinoid systems interaction in the pathogenesis of Parkinson`s disease and psychiatric comorbidity 20 biomedica Biobehavioral and Behavioral Processes , GR ENTIFICATION OF NOVEL AUTOANTIBODIES ASSOCIATED WITH IOPATHIC RETROPERITONEAL FIBROSIS 20 biomedica Immunology , GR "A new model for the mandibular reconstruction" 20 biomedica Musculoskeletal, Oral and Skin Sciences , GR Functional characterization of the CCDC6 gene product, a protein responsible for a new mechanism of genome instability and a novel diagnostic and prognostic marker of human neoplasias. 20 biomedica Oncology 1 Basic , GR Urethral reconstruction on bio adsorbable scaffold promoting urothelial stem cells migration in mini pig model. 20 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , GR Development of a new EGFR based therapy targeting the activated NHERF1 EGFR NHE1 axis in pancreatic ductal adenocarcinoma 20 biomedica Oncology 1 Basic , RF An Italian multicentric prospective phase III randomized, placebo controlled blinded investigation of six weeks vs. sixteen weeks of oral valganciclovir therapy in infants with symptomatic congenital cytomegalovirus infection. 20 clinico assistenziale Infectious Diseases and Microbiology , GR CREATION OF A BIOLOGICAL BANK OF THE POPULATION BASED REGIONAL REGISTRY OF PATIENTS WITH AMYOTROPHIC LATERAL SCLEROSIS: A STEP TOWARDS CLINICAL AND PATHOGENETIC STUDIES IN EMILIA ROMAGNA REGION. 20 clinico assistenziale Brain Disorders and , RF Use of Platelets Rich Plasma in the treatment of Achilles Tendinopathy to reduce tendon ruptures 20 clinico assistenziale Musculoskeletal, Oral and Skin Sciences ,00 Pagina 170 di 244

171 RF Cryo focal therapy for prostate cancer: a stage 2a b phase 20 clinico assistenziale Digestive, Kidney and Urological Systems GR New anti VEGF strategies in adrecocortical tumors 20 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , , RF Development of innovative molecular markers as tools for the rapid and accurate detection of Anisakis, etiological agents of a fish borne zoonosis, in fish and squids: from the epidemiology to the diagnosis in humans 20 biomedica Veterinary Food Safety FOSA , RF BIOMORPHOLOGICAL, CULTURAL AND CLINICAL STUDY ON LONG TERM CRYOPRESERVED MESENCHYMAL STEM CELLS FROM EQUINE ADIPOSE TISSUE 20 biomedica Biology of Development and Aging , GR HYPERBRAIN How brains interact during real life social situations: simultaneous multi subject recording of high resolution EEG and autonomic signals 20 biomedica Bioengineering Sciences and Technologies , GR Herpes simplex virus and the cross talk between the NF kb and the HIF signaling pathways: implications in hypoxia/ischemia associated brain injury. 20 biomedica Infectious Diseases and Microbiology , GR Effect of mesenchymal stromal cells (MSCs) on tumor angiogenesis: potential implications in the therapy of human cancer 20 biomedica Oncology 1 Basic , GR High resolution quantification of MR biomarkers in deep structures of the human brain: investigation of the thalamus and basal ganglia. 20 clinico assistenziale Brain Disorders and , RF Multidisciplinary vs Monodisciplinary Clinic for Prostate Cancer Patients: Evaluating patients satisfaction and Multidisciplinary Team working 20 clinico assistenziale Healthcare Delivery and Methodologies , RF Characterization of colon cancer stem cells for the identification of new prognostic markers and/or targets for novel anticancer therapies 20 biomedica Oncology 1 Basic , GR Involvement of the proteasome degradation pathway and molecular chaperones in sporadic and familial neurodegenerative diseases 20 biomedica Molecular, Cellular, and Developmental Neuroscience ,00 Pagina 171 di 244

172 1950 GR Evaluation of inflammatory status in plasma of atherosclerotic patients and healthy controls 20 biomedica Vascular and Hematology 1951 GR Metabolic profile in urine and blood for the identification of biomarkers of bladder cancer 20 biomedica Oncology 2 Clinical , RF TRIAL STUDY TRAINING IN ITALIAN AGINGS WITH HEART FAILURE 20 clinico assistenziale Risk, Prevention and Health Behavior RF Hypoxia, inflammation and stem cells in cancer progression 20 biomedica Oncology 1 Basic , , GR A comparative analysis of amniotic fluid and amniotic membrane derived cells: immunophenotypic characterization, genomic stability, gene expression modulation and in vitro stem cell potential evaluation. 20 biomedica Biology of Development and Aging , GR New strategies of intervention in cancer involving the insulin receptor isoform A 20 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Biochemical and ultrasonographic screening of pre eclampsia in the first gestational trimester. 20 clinico assistenziale Healthcare Delivery and Methodologies , GR Small Molecule Inhibitors Targeting MDM4/MDM2 Complex: Delivering a Novel Therapeutic Opportunity for Cancer Disease 20 biomedica Oncology 2 Clinical , RF BIOLOGICAL MARKERS PREDICTIVE FOR EFFICACY AND SAFETY OF PHARMACOTHERAPY IN BOYS WITH ATTENTION DEFICIT HYPERACTIVITY DISORDER: VALATION OF FINDINGS GENERATED IN ANIMAL MODELS 20 clinico assistenziale Brain Disorders and 1959 GR A novel transgenic mouse as a tool to study the role of IL 7 in the pathogenesis of multiple sclerosis and inflammatory bowel disease. 20 biomedica Immunology , GR Proteomic Biomarkers for IgA Nephropathy: the Interstiome Strategy 20 clinico assistenziale Digestive, Kidney and Urological Systems RF Prospective evaluation of screening for sight threatening diabetic retinopathy 20 clinico assistenziale Healthcare Delivery and Methodologies , ,00 Pagina 172 di 244

173 1962 GR translating biology into clinic: a molecular approach for the identification of target key factors to combat glioma diffuse growth 20 biomedica Oncology 1 Basic , RF The role of hypoxia and hypoxia response in allogeneic hematopoietic stem cells transplant 20 biomedica Oncology 1 Basic , GR ASSESSING THE FUNCTIONAL ROLE OF 6 sulfo LacNAc+ DENDRITIC CELLS (slandc) IN THE RECONSTITUTING IMMUNE SYSTEM AFTER HEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT) AND IN THE TUMOUR MICROENVIRONMENT 20 biomedica Immunology , GR Flavonoids and cancer risk, with focus on proanthocyanidins derived from apples: a network of case control studies from Mediterranean countries. 20 clinico assistenziale Population Sciences and Epidemiology , GR Frequency of peripheral CD4 + subset, expression of Killer Immunoglobulin Like Receptors (KIRs) and Signaling Proteins Regulating the Cytotoxic Function of CD4 T Cells in subjects with acute ischemic stroke 20 biomedica Brain Disorders and , RF Staphylococcal enterotoxin risk assessment in traditional raw ewe milk Pecorino cheese 20 biomedica Veterinary Food Safety FOSA , RF Development of RNAi mediated silencing strategies for the design of tumourtargeted therapies of neuroectoderma derived tumours 20 biomedica Oncology 2 Clinical , RF Environmental, occupational, and genetic factors in the etiology of lung cancer in EAGLE, a population based case control study 20 clinico assistenziale Population Sciences and Epidemiology , RF Prevalence of respiratory diseases related to climate and air pollution: a survey among young adults in Puglia. 20 clinico assistenziale Population Sciences and Epidemiology , RF Childhood obesity prevention project on high risk young children and development of a regional Pediatric Network for childhood obesity prevention and care 20 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF ROLE OF ADAPTIVE AND HUMORAL IMMUNITY IN CORONARY AND MYOCARDIAL VULNERABILITY 20 clinico assistenziale Vascular and Hematology ,00 Pagina 173 di 244

174 1973 RF Oncomirs as new biomarkers and/or therapeutic target for soft tissue sarcomas 20 biomedica Oncology 1 Basic , RF Effectiveness of repeated immunizations with DNA plasmids encoding HER 2/neu in the long term prevention of mammary cancer in HER 2/neu transgenic mice 20 biomedica Biology of Development and Aging , RF SENESCENCE ASSOCIATED micrornas (SAmiRs) IN CELLULAR SENESCENCE, NEOPLASTIC TRANSFORMATION AND ORGANISMAL AGING 20 biomedica Biology of Development and Aging , RF Identification of telomere maintenance mechanism related genes and mirnas as prognostic and therapeutic tools. 20 biomedica Oncology 1 Basic , RF Inhibition of telomerase: a therapeutic strategy for disruption of glioblastoma multiforme development 20 biomedica Oncology 1 Basic , RF CHARACTERIZATION OF MECHANISMS CONTROLLING GLOMERULAR SCLEROSIS. FROM THE EXPERIMENTAL MODEL TO THERAPY 20 biomedica Digestive, Kidney and Urological Systems , RF Connexin related hereditary hearing loss: Pathogenetic mechanisms and therapeutic perspectives 20 biomedica Genes, Genomes and , RF Mapping Progressive Neurodegeneration in FTLD: a Multiparametric Study combining Biological, Clinical, Neuropsychological, and Neuroimaging Assessment 20 clinico assistenziale Brain Disorders and 1981 RF Development of new orthobiologic products from tissue engineering for the regenerative and reparative medicine of the osteochondral tissue 20 biomedica Musculoskeletal, Oral and Skin Sciences , RF A nationwide analysis on the effect of therapies in patients with chronic inflammatory demyelinating polyneuropathy: cost utility analysis of intravenous immunoglobulin and steroid. 20 clinico assistenziale Brain Disorders and , RF Prospective study on Bone Mineral Density and bone quality in post menopausal women affected with Diabetes Mellitus type 2: role of hypothalamus pituitaryadrenal (HPA) axis and glucocorticoid sensitivity. 20 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences 1984 RF Gene networking of primary hypertension and related organ complications: a strategy for individual therapy 20 clinico assistenziale Cardiovascular and Pagina 174 di 244

175 1985 RF Salivary gland tumours: a study of immunohistochemical markers, cancer genes, and genomic imbalances for detection of diagnostic and prognostic markers 20 biomedica Oncology 1 Basic , RF Bacterial virulence factors and MicroRNAs' profiling in colon cancer 20 biomedica Oncology 1 Basic RF Role of tissue microenvironment in lung cancer development 20 biomedica Oncology 1 Basic , , RF Children and adolescent obesity: assessment of early markers of cardiovascular and cancer risk in a cohort of school children and adolescents in the metropolitan area of Pisa (north west Tuscany). Set up of a multi parameter score system to recognize chil 20 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Hypertrophic cardiomyopathy (HCM) and its aetiopathogenesis: search for new HCM causing genes and mutations and analysis of cardiac microrna regulatory role 20 biomedica Genes, Genomes and , GR Impact of neuroinflammation on adult neurogenesis: analysis of the modulatory role of different microglial phenotypes on neural stem cell fate determination. 20,17 biomedica Molecular, Cellular, and Developmental Neuroscience , GR in vivo antitumor effects of gamma and delta tocotrienol on HER 2/neu positive breast carcinoma in young and old ages 20,17 biomedica Biology of Development and Aging , RF DOPAMINERGIC MODULATION OF CD4+ T LYMPHOCYTES: RELEVANCE FOR NEURODEGENERATION AND NEUROPROTECTION IN PARKINSON S DISEASE THE DOPAMINERGIC NEURO IMMUNE CONNECTION 20,17 biomedica Brain Disorders and , RF New molecular targets for prognostic definition and therapeutic intervention in prostate cancer patients: from bench to clinic 20,17 biomedica Oncology 1 Basic 1994 GR Mechanisms of cortical brain damage in multiple sclerosis: a combined molecular, neuropathological and ultra high field imaging study 20,25 biomedica Brain Disorders and , GR Drug resistance in leukemia: role of small noncoding RNA (mirnas) and the redox status of cells. 20,25 biomedica Oncology 2 Clinical ,00 Pagina 175 di 244

176 1996 RF EA: Immediate versus Delayed Erlotinib After front line chemotherapy in advanced Non Small Cell Lung Cancer. A randomized phase 3 clinical trial. 20,25 clinico assistenziale Oncology 2 Clinical , RF Exercise and molecular pathways promoting axonal growth following spinal cord injury. 20,25 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Protective mechanisms during cardiopulmonary resuscitation: role of selective head cooling 20,25 biomedica Cardiovascular and , GR Early Diagnosis of Neurodegenerative Disorders: Absolute Quantification of Metabolic Markers by 1H Magnetic Resonance Spectroscopy at 3 Tesla. 20,25 clinico assistenziale Brain Disorders and , GR Clinical and prognostic relevance of vitamin d deficiency in acute coronary syndromes 20,25 clinico assistenziale Cardiovascular and , RF A phase I II trial of suicide gene therapy with central memory donor T cells in the context of haploidentical hematopoietic stem cell transplantation for the treatment of acute leukemia in relapse 20,25 biomedica Oncology 2 Clinical 2002 GR Sleep disruption as a basis for visual hallucinations and nocturnal confusional behaviours in DLB and PDD: a 24 hour continuous polysomnographic study before and after rivastigmine. 20,25 clinico assistenziale Brain Disorders and , GR THERAPEUTIC APPROACHES TO PRION DISEASES BASED ON NANOMEDICINE AND GENE THERAPY 20,25 biomedica Molecular, Cellular, and Developmental Neuroscience , GR IMMUNEMONITORING OF T CELL RESPONSES ELICITED BY LOCAL TREATMENT OF MELANOMA LESIONS THROUGH ELECTROCHEMOTHERAPY 20,25 clinico assistenziale Oncology 2 Clinical , RF STUDY OF STEREO EEG SIGNALS BASED ON EFFECTIVE CONNECTIVITY IN PATIENTS WITH REFRACTORY EPILEPSY: A TOOL TO ENTIFY THE EPILEPTOGENIC ZONE AND SUPPORT SURGICAL STRATEGY 20,25 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Molecular biomarkers for lung cancer diagnosis 20,25 clinico assistenziale Oncology 2 Clinical ,00 Pagina 176 di 244

177 2007 RF NOVEL THERAPEUTIC APPROACH TO OVERCOME BCL 2 RELATED DRUG RESISTANCE IN CHOLANGIOCARCINOMA: A SHIFT FROM A TUMOR TYPE APPROACH TO A PATIENT BASED APPROACH 20,25 biomedica Oncology 2 Clinical , GR METABOLIC AND CARDIOVASCULAR FEATURES IN PATIENTS WITH TURNER'S SYNDROME AND AUTOIMMUNE PREMATURE OVARIAN FAILURE 20,34 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR TSC2 CELLS IN THE PATHOGENESIS OF RARE DISEASES: TUBEROUS SCLEROSIS AND LYMPHANGIOLEIOMYOMATOSIS. A CELLULAR, MOLECULAR AND PHARMACOLOGICAL STUDY. 20,34 biomedica Cell Biology , RF Endemic and epidemic clones of Escherichia coli that cause antimicrobialresistant extraintestinal infections in humans: born in the community or in the farmyard? 20,34 biomedica Infectious Diseases and Microbiology , RF Environmental and occupational exposure assessment to endocrine disrupters 20,34 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences 2012 RF Characterization of novel RGD based integrin targeted agents for cancer imaging and therapy 20,34 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Human DNA Topoisomerase I mutations that induce drug resistance: a prospective study 20,34 biomedica Oncology 1 Basic , GR HIP AND KNEE REPLACEMENT IN FRAGILE INPATIENT: GROUP VERSUS INDIVUAL MULTISCIPLINARY REHABILITATION 20,5 clinico assistenziale Healthcare Delivery and Methodologies , RF UNRESECTABLE IN TRANSIT METASTATIC MELANOMA: ELECTROCHEMOTHERAPY VERSUS ELECTROIMMUNOTHERAPY. LOCAL AND SYSTEMIC EFFECTS. 20,5 clinico assistenziale Oncology 2 Clinical , RF The role of complementary clinical and molecular research in the understanding of nevus evolution, stabilization and involution 20,5 biomedica Oncology 1 Basic ,00 Pagina 177 di 244

178 2017 RF EFFECT OF HAART ON HIV IMMUNE DYSREGULATION: role of multispliced RNA and drug induced secretome. 20,5 biomedica AS and Related Research , GR Human mesenchymal stem cells (hmscs) as novel therapeutic tool in neurodegenerative diseases: study of the role of purinergic receptors in hmscs transdifferentiation in vitro into neuronal lineages. 20,5 biomedica Biology of Development and Aging , GR Effect of Glucosamine and Vitamin D on Human Osteoarthritic Cartilage 20,5 biomedica Musculoskeletal, Oral and Skin Sciences , GR Evaluation of Metallothioneins auto antibodies directed against human Metallothioneins in the serum of diabetes type 2 and in old subjects in relation to MT1A polymorphisms 20,5 biomedica Immunology , GR Metabolomics of Bone Malignancies 20,5 biomedica Biological Chemistry and Macromolecular Biophysics RF Vitamin D binding protein as a new biological marker of prostate cancer 20,5 biomedica Oncology 2 Clinical , , RF ELECTROCHEMOTHERAPY IN ANIMAL MODEL TO IMPROVE NEW CANCER TREATMENT 20,5 biomedica Oncology 2 Clinical , GR Modularity for sensory motor control: a study in the first year after a brain lesion. 20,5 biomedica Biobehavioral and Behavioral Processes , GR Evaluation of pulmonary function after ex vivo reperfusion of lungs unelegible for transplantation: an experimental study 20,5 biomedica Cardiovascular and , GR Diagnosis of extra vascular lung water by means of ultrasound comets analysis: development of a new methodology and apparatus. 20,5 biomedica Cardiovascular and , RF REGULATORY T CELLS IN THE MILD COGNITIVE IMPAIRMENT AND THEIR PROGNOSTIC VALUE TOWARDS THE CONVERSION TO CLINICALLY DEFINED ALZHEIMER s DISEASE 20,5 biomedica Brain Disorders and , RF Role of immunological impairment in myeloma progression: identification of new molecular targets for anti neoplastic immunity. 20,5 biomedica Oncology 1 Basic ,00 Pagina 178 di 244

179 2029 RF Progressive Multifocal leukoencephalopathy and JC Virus: a combined molecular, genetic and proteomic investigation for the discovery of new prognostic biomarkers and antiviral treatments. 20,5 biomedica Brain Disorders and , RF Zoonotic risks related to the handling and consumption of meat from wild ungulates mainly hunted in Italy (wild boar / Sus scrofa, roe deer / Capreolus capreolus, red deer / Cervus elaphus and chamois / Rupicapra rupicapra). 20,5 biomedica Veterinary Food Safety FOSA 2031 GR MARKERS OF NEURODEVELOPMENTAL IMPAIRMENT IN A MODEL OF MATERNAL IMMUNE ACTIVATION 20,5 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Long term oral melatonin in patients with Cystic Fibrosis: A Randomized Controlled Trial 20,5 clinico assistenziale Cardiovascular and , RF HGF/c MET, PI3K/PTEN, IGF 1/IGF 1R and AKT/mTOR pathways in gastric cancer. Assessments in vivo and implications for developing novel therapeutic strategies. 20,5 biomedica Oncology 2 Clinical , GR Role of the scaffold molecule KSR2 in immune cells deficiency associated to obesity: studies in mice models and humans 20,5 biomedica Immunology , RF Incidence, management, comorbidity, and prognosis of patients hospitalized for Venous ThromboEmbolism in Sardinia (ivte S) 20,5 clinico assistenziale Healthcare Delivery and Methodologies , GR Effects of robotic aided rehabilitation on the wrist joint in hemiparetic patients: a fmri study 20,5 biomedica Musculoskeletal, Oral and Skin Sciences , RF Role of glycation/glycoxidation products in the pathogenesis of atherosclerosis: a search for new biomarkers of increased cardiovascular risk 20,5 biomedica Cardiovascular and , RF Relevance of BACE1 expression in Alzheimer's disease: identification of new regulators of BACE1 expression by in vitro and in vivo approaches 20,5 biomedica Molecular, Cellular, and Developmental Neuroscience , RF mir 221/222 and mir 145 in the biology of glioblastoma multiforme 20,5 biomedica Oncology 1 Basic ,00 Pagina 179 di 244

180 2040 RF Factors predictive of response to anti Hepatitis C Virus treatment or neoplastic progression or immune protection: a study by gene expression profiles and Functional cell assays in innate immune cells. 20,5 biomedica Immunology , RF Surgical versus Transcatheter Aortic Valve Implantation for the treatment of Severe Isolated Aortic Valve Stenosis 20,67 clinico assistenziale Cardiovascular and , RF I2D2 Information Integrated DNA Database Designing a Network to hereditary cancer sharing an integrated database of molecular oncology and dissemination of information for the management of multicentric patients and their families in ASL Lecce. 20,67 biomedica Oncology 1 Basic , RF A novel strategy to implement appropriate prescribing and reduce the morbidity burden in patients with comorbid chronic obstructive pulmonary disease (COPD) and ischemic heart disease (IHD) or heart failure (HF): a cluster randomized trial of an in hospit 20,67 clinico assistenziale Cardiovascular and , GR Automatic non invasive system to Detect and characterize VitAl mesenchymal stem Cells in a spatio temporal context (ADVANCE) 20,67 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Red Ox proteomic and cell biology studies about the E5 oncoprotein of Human Papillomavirus type 16. A potential candidate for improved molecular markers of genital infection and carcinogenesis. 20,67 biomedica Oncology 1 Basic , RF Effect of metabotropic glutamate receptor subtype 7 (mglu7) blockade on neuropathic pain symptoms, anxiety related behaviour and neural death 20,7 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Genotyping and Expression profiling of sex steroid related genes associated with autistic traits and Autism Spectrum Disorders. 20,75 biomedica Biobehavioral and Behavioral Processes , GR Molecular characterization of B cell Chronic Lymphocytic Leukemia (B CLL): integrative genomic approach by using microarray technologies 20,75 biomedica Genes, Genomes and , RF Study of genetic structure of adult and paediatric patients affected by c KIT related disease (mastocytosis, chronic myeloprolipherative diseases and acute leukemia) using array CGH technology in order to detect the presence of numerical and structural ch 20,75 biomedica Genes, Genomes and ,00 Pagina 180 di 244

181 2050 GR Zinc oxide application in the treatment of Periprosthetic infection 20,75 biomedica Infectious Diseases and Microbiology , GR A new pharmacological approach for the treatment of andrological diseases of the testis with low blood flow and reduced fertility 20,75 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR mrna and microrna expression profiles in peripheral blood as non invasive diagnostic and prognostic markers of non small cell lung cancer (NSCLC) 20,75 biomedica Oncology 2 Clinical , GR a randomised phase II trial of second line therapy in advanced biliary tract cancer: capecitabine vs capecitabine plus mitomycin 20,75 clinico assistenziale Oncology 2 Clinical 0, RF Comparison of clinical results after treatment and biological characteristics of screen detected vs non screen detected vs interval colo rectal carcinomas 20,75 clinico assistenziale Oncology 2 Clinical , GR PULMONARY FUNCTION AND KINEMATICS IN PATIENTS WITH PECTUS EXCAVATUM: EFFECT OF SURGICAL TREATMENT 20,75 clinico assistenziale Cardiovascular and , GR Identification of novel prognostic factors in Hodgkin's Lyphoma through the realization of a multidsciplinary platform 20,75 clinico assistenziale Oncology 2 Clinical 2057 RF Phage therapy: a new weapon for the environment, animal and public health. An application example: Shiga toxin producing Escherichia coli (STEC) zoonoses established in industrial countries 20,75 biomedica Veterinary Animal Health ANHE , GR Study of the effects of the hepatitis C virus on the biogenesis of low density lipoproteins: development of new antiviral strategies 20,84 biomedica Infectious Diseases and Microbiology , GR SINGLE NUCLEOTE POLYMORPHISMS OF SNAP 25 AS BIOMARKERS FOR AUTISM SPECTRUM DISORDERS 20,84 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Establishment of an interdisciplinary research unit for the study of fatigue in the elderly 20,84 biomedica Biology of Development and Aging , RF Development of innovative therapies: new molecular targets sustaining metastatic potential of Breast CSCs 20,84 biomedica Oncology 1 Basic ,00 Pagina 181 di 244

182 2062 RF Nigrostriatal damage and hepatic dysfunction in experimental Parkinson's disease: a potential link underlying self perpetuating neurodegeneration and a potential target for neuroprotection 20,84 biomedica Brain Disorders and , RF CLINICAL MANAGEMENT OF CRYOGLOBULINAEMIA SECONDARY TO HCV INFECTION BASED ON A NEW SPECTROPHOTOMETRIC TEST 20,88 biomedica Biological Chemistry and Macromolecular Biophysics , RF Changes in structure and recruitment of muscle synergies after cortical and cerebellar lesions 21 biomedica Integrative, Functional, and Cognitive Neuroscience , RF Searching for a common pathogenetic pathway causing muscle misfunctioning in different laminopathies 21 biomedica Cell Biology , RF Mechanisms of stem cell platelet interaction in the reparative process of the ischemic damage in cardiovascular patients 21 biomedica Cell Biology , GR Analysis of cortical EEG/MEG rhythms and non invasive brain stimulation for the therapy of insomnia 21 biomedica Integrative, Functional, and Cognitive Neuroscience , GR A novel cardiac MRI approach to study Early Myocardial Interstitium Remodeling in Dilated Cardiomyopathy 21 clinico assistenziale Cardiovascular and , GR The effect of hypertension on female genital vascular activity 21 biomedica Digestive, Kidney and Urological Systems , GR Myocardial ischemia beyond atherosclerosic plaque and endothelial dysfunction: role of genetic polimorphysm for ion channels 21 clinico assistenziale Cardiovascular and , GR Integrated therapeutic drug monitoring and pharmacogenetics strategies for the optimal management of transplanted HIV patients 21 clinico assistenziale AS and Related Research 2072 GR The neuropathological and neurochemical substrates of gastrointestinal dysfunction in a rodent model of Parkinson's disease: prospects for the development of new therapeutic strategies 21 biomedica Brain Disorders and ,00 Pagina 182 di 244

183 2073 GR Dissecting neuron like signalling in the podocyte and the osteocyte to uncover early mechanisms of mineral metabolism alterations during renal damage. 21 biomedica Digestive, Kidney and Urological Systems , RF Use of clinical care variables with social and economic impact in the treatment of frail, elderly patients suffering from heart disease 21 clinico assistenziale Cardiovascular and , GR Clinical Decision Support Systems and Membrane Computing 21 clinico assistenziale Healthcare Delivery and Methodologies , RF A multidisciplinary approach for molecular biomarkers in Mild Cognitive Impairment: evaluation of genetic, biochemical and neuroimaging patterns. 21 biomedica Molecular, Cellular, and Developmental Neuroscience , GR ROLE OF EXERCISE TRAINING IN PREVENTION AND TREATMENT OF AGE RELATED CHRONIC DEGENERATIVE DISORDERS. ANALYSIS OF THE ROLE PLAYED BY OXATIVE STRESS, SIRT1 EXPRESSION, AND mtor AND enos SIGNALLING PATHWAYS IN HUMANS AND RATS 21 biomedica Biology of Development and Aging , GR Platinum derived chemotherapy in Malignant Mesothelioma patients: impact of ABCC2 genetic polymorphisms on plasma levels of the drugs, clinical outcome and toxicity 21 biomedica Oncology 1 Basic , GR Synergism between natural products from lichens and antibiotics against Gramnegative non fermenting bacteria expressing a Multi Drug Resistant phenotype. Effects on planktonic life and biofilm formation 21 biomedica Infectious Diseases and Microbiology 2080 RF Novel therapeutic approaches targeting the cross talk between mesenchymal stem cells and tumor cells in breast cancer 21 biomedica Oncology 1 Basic , GR Esmolol as cardioplegia adjuvant in high risk cardiac surgery patients. A multicentre randomized placebo controlled trial. 21 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , GR Harnessing autophagy to promote cell death of metastatic tumors 21 biomedica Oncology 1 Basic , RF Nutritional and environmental determinants of bone growth and development in children 21 biomedica Population Sciences and Epidemiology ,00 Pagina 183 di 244

184 2084 GR Development of an experimental biological protocol able to the characterisation of new buccal and transbuccal dosage forms for local and systemic pharmacological therapies. 21 biomedica Bioengineering Sciences and Technologies , GR Plasticity of body and space representations: rehabilitative programs in the field of prosthetic devices and treatment of neuropsychological and neuropsychiatric deficits 21 clinico assistenziale Integrative, Functional, and Cognitive Neuroscience , GR Role of Toll Like Receptors 4, 9 and MyD88 adaptor in the pathogenesis of multiple sclerosis: analysis using immunomodulatory compounds 21 biomedica Immunology , RF linking the genetic level to mechanic and dielectric properties of physiological and pathological human diseases 21 biomedica Bioengineering Sciences and Technologies , GR New strategies for the repair of epileptogenic neuronal damage 21 biomedica Brain Disorders and 0, GR Role of mirnas in Alzheimer s disease and Frontotemporal Lobar Degeneration: from pathogenesis to biomarker discovery 21 biomedica Genes, Genomes and , RF micrornas' EXPRESSION IN HEAD AND NECK SQUAMOUS CELL CARCINOMA AND IN AUTOLOGOUS PERI TUMORAL AND NORMAL TISSUES 21 clinico assistenziale Oncology 2 Clinical , GR A human recombinant Manganese Superoxide Dismutase (rmnsod) protects Mice exposed to Dioxine intoxication from Carcinogensis and Teratogenesis risk. 21 biomedica Veterinary Animal Health ANHE , RF Anti HCV treatment outcome in HCV/HIV co infected patients: the role of dendritic cells 21 biomedica Immunology , RF LEUKODYSTROPHIES OF THE ADULTS: DEVOLOPMENT OF A DIAGNOSTIC PROTOCOL AND ASSESSMENT OF PATHOGENETIC MECHANISMS 21 clinico assistenziale Brain Disorders and , GR Molecular profiling of glycosaminoglycans in MO patients: evaluation of pathophisiological alterations to define biomarkers for diagnosis and patients follow up 21 biomedica Biological Chemistry and Macromolecular Biophysics ,00 Pagina 184 di 244

185 2095 GR Can the nanotechnology be useful for neurodegenerative diseases such as Alzheimer disease (AD)? A preclinical study of new target drug formulation CeO2 nanoparticles based as a promising innovative tool for AD treatment. 21 biomedica Brain Disorders and , GR Identification of new histone acetylase inhibitors with potential antitumor activity 21 biomedica Oncology 2 Clinical , RF Usefulness of ultra high field (7T) brain imaging in candidates for neurosurgical treatment of epileptogenic brain lesions 21 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , GR Role of metabotropic glutamate receptors in monogenic autism: new targets for pharmacological therapy 21 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Morpho Functional characterisation of human white adipose tissue 21 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF METABOLOMIC PROFILE OF URINE AND SERA BIOMARKERS IN FANCONI ANEMIA 21 biomedica Healthcare Delivery and Methodologies , GR Implementation of an Amniotic Fluid Derived Mesenchymal Stromal Cells RDG Polyurethanes/Hydroxyapatite Based Bioprosthesis: An In Vivo Evaluation Study. 21 biomedica Bioengineering Sciences and Technologies , GR Tissue biomarkers with diagnostic and prognostic significance in hepatocellular carcinoma. 21 biomedica Oncology 2 Clinical , RF Integrated Network Data Analysis System for OncoGenomics (INDAS OG) 21 biomedica Bioengineering Sciences and Technologies , RF Role of mechanotransduction signals and sirtuins in rehabilitation coupled with physical activity 21 biomedica Musculoskeletal, Oral and Skin Sciences , RF Role of Toll like receptor 2 in collateral vessels development after acute ischemia 21 biomedica Cardiovascular and ,00 Pagina 185 di 244

186 2106 RF Clinical, functional imaging, molecular and biochemical investigation of novel gene and therapeutic targets involved in Angelman syndrome 21 biomedica Brain Disorders and , RF Muscular disorders and muscle cell apoptosis: the role of melatonin 21 biomedica Cell Biology , RF Gastrokine 1 and Gastric Cancer: role of the protein as tumor biomarker and tumor suppessor to optimize diagnosis and therapy of gastric carcinogenesis 21 biomedica Biological Chemistry and Macromolecular Biophysics , GR Hemo Dialysis treatment optimization and customization by means of patient specific hydro electrolytic and hemodynamic modelling 21 biomedica Digestive, Kidney and Urological Systems , RF Organization models and informatic technology for the integrated management of chronic heart failure 21 clinico assistenziale Healthcare Delivery and Methodologies , RF OBSERVANT OBservational Study of Effectiveness of avr tavi procedures for severe Aortic stenosis Treatment 21 clinico assistenziale Healthcare Delivery and Methodologies 2112 GR A new chemico pharmacological approach to heart regeneration: use of "small molecules" to generate cardiac progenitor cells and to induce their differentiation into cardiac myocytes 21 biomedica Cardiovascular and , RF The role of chronic inflammation in cognitive impairment syndromes 21 biomedica Brain Disorders and , RF A new therapeutic approach for treating pancreatic cancer: use of Aurora B kinase inhibitors 21 biomedica Oncology 1 Basic , GR Congenital Hyperinsulinism: from the Italian epidemiology to the discover of novel related genes. 21 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Characterization of cancer stem cells and drug resistance markers for targeted therapy of uveal melanoma: synthesis of new inhibitors of ABC transporters and development of new animal models of metastatic disease. 21,17 biomedica Oncology 1 Basic , GR fmri neuroimages voxel based processing via CUDA for brain function assessment 21,17 clinico assistenziale Bioengineering Sciences and Technologies ,00 Pagina 186 di 244

187 2118 RF METAL ION INDUCED MOLECULAR DAMAGE IN PATIENTS WITH ORTHOPAEDIC IMPLANTS 21,17 clinico assistenziale Oncology 1 Basic , GR Identification of prognostic markers in posttransplant lymphoproliferative disorders: genetic lesions in peripheral blood lymphocytes during infection with viruses of the herpesviridae family 21,2 biomedica Oncology 1 Basic , GR Surveillance of the circulation of enteric viruses in the infantile population of Sicily following the introduction of rotavirus vaccines. 21,25 biomedica Population Sciences and Epidemiology , GR Advanced phenotypic and functional laboratory diagnostics in clinical lipidology: toward a more correct patient cardiovascular risk characterization for a more appropriate prescription of diagnostic exams and drug prescription 21,25 clinico assistenziale Cardiovascular and , RF Understanding human skeletal diseases and developing novel therapeutic strategies by using Zebrafish models 21,25 biomedica Genes, Genomes and , RF Validation of the Framingham Heart Study risk score for atrial fibrillation in a community based prospective cohort study in Alto Adige 21,25 clinico assistenziale Cardiovascular and , GR In depth characterisation of the immune response in the population of South African individuals enrolled in the clinical study A Multicentre, Observational, Cross Sectional Study to Assess the Seroprevalence of Anti Tat Antibodies in HIV Infected Patient 21,25 clinico assistenziale AS and Related Research , GR Longitudinal multi parametric structural and functional MR of the brain in degenerative diseases of the motor system. 21,25 biomedica Brain Disorders and , GR Virological and viro immunological monitoring of polyomavirus JC in patients with multiple sclerosis treated with natalizumab. 21,25 clinico assistenziale Infectious Diseases and Microbiology , GR ENTIFICATION OF PROTECTIVE GENETIC FACTORS IN CARRIERS OF THE E200K PRNP MUTATION 21,25 biomedica Genes, Genomes and , RF In vitro culture of human male germ cells for couples at risk for chromosomal aneuploidy or monofactorial genetic disorders 21,34 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences ,00 Pagina 187 di 244

188 2129 GR New methodologies for non invasive, quantitative and Automatic MOnitoring of childbirth LABor (AMOLAB) 21,34 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Prospective within patient study to assess feasibility and accuracy of real time endoscopic trans urethral in vivo staging and grading of bladder cancerous lesions by mean of optical coherence tomography combined with narrowband imaging modality 21,34 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Translating molecular knowledge into colorectal cancer clinical management 21,34 biomedica Oncology 1 Basic , RF Identification and preclinical validation of new strategies for targeted therapy against head and neck tumors 21,5 biomedica Oncology 2 Clinical , RF CT SCREENING FOR LUNG CANCER WITH A RANDOMIZED STUDY AMONG DIFFERENT SMOKING CESSATION STRATEGIES 21,5 clinico assistenziale Risk, Prevention and Health Behavior 2134 GR Validation of a prognostic score in clinically isolated syndromes and early relapsing remitting multiple sclerosis. 21,5 clinico assistenziale Population Sciences and Epidemiology , RF Large scale identification of disease causing mutations and genetic variants predisposing to heart failure in patients with hypertrophic cardiomyopathy 21,5 biomedica Cardiovascular and , RF Role of endothelial nitric oxide synthase (enos) gene polymorphisms and peripheral biomarkers related to the nitric oxide pathway in the prediction of recurrent cardiovascular events in patients with CHD (CARDIO DIABETES study). 21,5 clinico assistenziale Cardiovascular and 2137 RF Pulmonary Arterial Hypertension Secondary to Chronic Obstructive Pulmonary Desease 21,5 clinico assistenziale Cardiovascular and , GR Proteomic Biomarkers to Detect Chronic Obstructive Pulmonary Disease (COPD) in Smokers 21,5 biomedica Cardiovascular and , RF The impact of maladaptive personality on the treatment of hospitalized psychiatric patients 21,5 clinico assistenziale Biobehavioral and Behavioral Processes ,00 Pagina 188 di 244

189 2140 GR Proteogenomics of adrenal cancer and benign adrenal neoplasia: new insights in the pathogenesis of adrenal masses 21,5 biomedica Oncology 2 Clinical , RF The role of autophagy in conditioning motor neuron survival 21,5 biomedica Brain Disorders and , RF Physical exercise in animal models of the human motor diseases Amyotrophic Lateral Sclerosis and Muscular Dystrophy of Duchenne type. Functional properties and synaptic plasticity of neocortical and hippocampal circuits. 21,5 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Role of endoglin and TGFBeta receptor complex in the pathogenesis of thoracic aortic aneurysms: a search for new predictive biomarkers 21,5 biomedica Cardiovascular and , GR Cognitive impairment in amyotrophic lateral sclerosis: a population based study 21,5 clinico assistenziale Brain Disorders and GR Potentially new and reemerging epidemics 21,5 biomedica Infectious Diseases and Microbiology , , RF A DNAchip for surveying: Development and clinical validation of an arrayedprimer extension technique for the detection and molecular characterization of aetiological agents of bacterial meningitis 21,5 biomedica Infectious Diseases and Microbiology , RF Identification of new genetic markers for a more accurate assessment of the real cardiovascular risk: a rapid and cost saving strategy 21,5 biomedica Vascular and Hematology , GR STUDY OF ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR (EDHF): A NOVEL APPROACH WITH CLINICAL IMPLICATIONS 21,5 biomedica Vascular and Hematology , RF In vitro and in vivo studies of the role of EFA6A, a guanosine exchange factor for the ARF6 small GTPase, in neuronal connectivity and in mental retardation 21,5 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Control of metastatic melanoma through immune intervention 21,5 biomedica Immunology , RF Surveillance, control and prevention of infections by multidrug resistant organisms in non hospital settings: nursing and residential homes 21,5 clinico assistenziale Infectious Diseases and Microbiology ,00 Pagina 189 di 244

190 2152 RF The "sweet side" of cancer: undermining the Hexokinase association with mitochondria for a generalized tumor therapy 21,5 biomedica Biological Chemistry and Macromolecular Biophysics , RF Prevalence and Etiology of StereoAnomalies (PESA) in Northern Italian young adults and seniors 21,5 biomedica Biobehavioral and Behavioral Processes , RF Identification of markers of muscle fibrosis and osteoporosis in Duchenne muscular dystrophy patients 21,5 biomedica Musculoskeletal, Oral and Skin Sciences , RF CLINICAL USE OF MAGNETIC RESONANCE WHOLE BODY IMAGING FOR EARLY DETECTION OF ACTIVE MULTIPLE MYELOMA BONE DISEASE 21,67 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , GR High throughput drug screening for bone regeneration using zebrafish as animal model 21,67 biomedica Musculoskeletal, Oral and Skin Sciences , RF Predictive value of integrated markers of inflammation and coagulation in an accelerated model of atherosclerosis 21,67 biomedica Cardiovascular and , RF Role of Oxidative Stress in Central Nervous System localization of Haematological Malignancies. A proteomics, flow cytometry and molecular study. 21,75 biomedica Oncology 2 Clinical , GR The abused child: a project/action based on multidsciplinary approach for a prevention strategy 21,75 clinico assistenziale Risk, Prevention and Health Behavior , GR Improving the management of Medication Overuse Headache and reducing its burden Long term outcome with two care approaches (in patient vs out patient) supported by an innovative electronic system 21,75 clinico assistenziale Healthcare Delivery and Methodologies , GR Behavioral and electrophysiological markers of decision making, and probabilistic learning associated with alcohol misuse in adults and cirrhotic patients with and without minimal hepatic encephalopathy 21,75 biomedica Integrative, Functional, and Cognitive Neuroscience , RF The Bloodless Cardiac Surgery Project A prospective quality study based on a comprehensive Patient Blood Management 21,75 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering ,00 Pagina 190 di 244

191 2163 RF Bacteriocin like inhibitory substance (BLIS) producing bacteria for decontamination of bivalve molluscs from pathogenic vibrios and Salmonella spp.: applicability assessment and development of experimental protocols. 21,84 biomedica Veterinary Food Safety FOSA , GR Human bone marrow mesenchymal stem cells: a new prospective for urine incontinence cell therapy 22 biomedica Cell Biology , GR Do Copy Number Variations contribute to phenotypic variability of Klinefelter syndrome? 22 biomedica Genes, Genomes and , GR Development of novel strategies for the evaluation of HIV/AS vaccine elicited immune responses and for the identification of correlates of protection/nonprogression 22 biomedica AS and Related Research , GR The vascular endothelial growth factor (VEGF) pathway in neuroendocrine tumors: in vitro and in vivo expression of VEGF and its receptors, prognostic role and evaluation of the response in vitro to specific VEGF inhibitors 22 biomedica Oncology 2 Clinical , RF Cardiovascular risk profiling in solid organ transplanted patients: identification of novel predictive biomarkers 22 clinico assistenziale Vascular and Hematology , RF Evaluation of the efficacy of a multitask training in patients affeceted by Multiple Sclerosis 22 clinico assistenziale Brain Disorders and , GR The role of insulin resistance on mitochondrial pathways on sarcopenia over aging 22 biomedica Biology of Development and Aging 2171 RF RANK/RANKL/OPG pathway in bone metastases of patients with neuroendocrine tumors 22 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR C di GMP as adjuvant of DNA Vaccination on HER 2/neu positive Mammary Carcinoma in young and old Ages 22 biomedica Biology of Development and Aging , RF INTERACTIONS BETWEEN BIOLOGICAL NETWORKS AS A TOOL TO DEFINE THE ROLE OF MOLECULAR TARGETED THERAPIES IN DIGESTIVE ENDOCRINE TUMOURS 22 biomedica Oncology 1 Basic ,00 Pagina 191 di 244

192 2174 GR THE ROLE OF POLYCYSTINS ON ERYTHROPOIESIS. 22 biomedica Digestive, Kidney and Urological Systems , GR Identification and characterisation of potential vectors and associated multispecies pathogens of animal in cattle dedicated environments 22 biomedica Veterinary Animal Health ANHE , GR Secondary alpha dystroglycanophaties: towards novel molecular diagnostic protocols. 22 biomedica Musculoskeletal, Oral and Skin Sciences , RF Transcription factor gene expression analyses in circulant mesenchymal stem cells in patients with degenerative diseases. 22 biomedica Genes, Genomes and , RF Determinants of HAART efficacy over older aged HIV infected population: observational study 22 clinico assistenziale AS and Related Research , RF AUTOLOGOUS CARDIAC CELL THERAPY WITH BONE MARROW DERIVED CD133+ CELLS IN PATIENTS WITH ADVANCED REFRACTORY CARDIOMYOPATHY: ARRHYTHMOLOGIC ASSESSMENT 22 clinico assistenziale Cardiovascular and , RF Type I interferons and Toll like receptors: two players in the pathological events of idiopathic inflammatory myopathies 22 biomedica Immunology , GR From genotype to beta cell phenotype and beyond: transcriptional and posttranscriptional effects of disease associated genes in human type 2 diabetes 22 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR ADVANCED GLYCATION ENDPRODUCTS IN DIET AND BLOOD, DEGLYCATING ENZYMES, AND CHRONIC DISEASES IN A COHORT OF OLDER PEOPLE IN SOUTHERN ITALY 22 biomedica Population Sciences and Epidemiology , RF BV8 prokineticin system in the immune associated pathophysiology of neuropathic pain 22 biomedica Biobehavioral and Behavioral Processes , GR Proposal for a Semantic Integration Framework for Health Technology Assessment (HTA) 22 biomedica Healthcare Delivery and Methodologies ,00 Pagina 192 di 244

193 2185 GR DYSLEXIA AND DYSGRAPHIA: DIFFERENT EXPRESSIONS OF A COMMON LINGUISTIC IMPAIRMENT OR MERE ASSOCIATION BETWEEN UNDERLYING COGNITIVE DEFICITS? A systematic study on the comorbidity between language impairment and learning disabilities 22 biomedica Brain Disorders and , RF FETUS (FEtalTeleUltraSound) CAMPANIA 22 biomedica Healthcare Delivery and Methodologies , GR Analysis of circulating tumour cells in peripheral blood and in pulmonary venous blood of patients submitted to surgery for non small cell lung cancer 22 clinico assistenziale Oncology 2 Clinical , RF Safeguarding the Health of the Immigrant Population. Analysis of Clinical and Epidemiological Aspects, Evaluation of the Health Services, Health Policies and Training Supply 22 clinico assistenziale Healthcare Delivery and Methodologies 2189 GR Role of the redox state of methionine 35 in synaptotoxicity induced by amyloidbeta peptide 22 biomedica Brain Disorders and , GR Evaluation of multi exposure to pesticides in a Sicilian population and biochemical correlates for in vitro induction of insulin resistance by cellular models. 22 biomedica Population Sciences and Epidemiology , GR Executive functioning in medical residents: effects of sleep debt and usefulness of napping as a countermeasure 22 clinico assistenziale Healthcare Delivery and Methodologies , GR EFFICACY AND BIOLOGICAL CORRELATES OF PSYCHOTHERAPY: THE EFFECTS OF A TIME LIMITED, PSYCHODYNAMIC APPROACH ON NEUROTROPHIC FACTORS IN PATIENTS WITH MAJOR DEPRESSION. 22 clinico assistenziale Brain Disorders and , RF Depression and coronary artery disease (CAD); the risk factors for the onset of depression in never depressed patients at their first episode of CAD and the effect of depression on the outcome of cardiopathy 22 clinico assistenziale Cardiovascular and , GR ROLE OF CBX7 IN HUMAN CANCERS 22 biomedica Oncology 1 Basic Pagina 193 di 244

194 2195 RF Pharmacological modulation of allergen induced inflammatory and dysfunctional alterations of the airways by PPAR (Peroxisome Proliferator Activated Receptors) ligands. 22 biomedica Cardiovascular and , GR Molecular characterization of the interaction between Pseudomonas aeruginosa clinical strains and cystic fibrosis airways 22 biomedica Infectious Diseases and Microbiology , RF EVALUATION OF APPROPRIATENESS, EFFICACY AND SAFETY IN CARE SETTINGS OF HOSPITALS FOR INTENSITY OF CARE 22 clinico assistenziale Healthcare Delivery and Methodologies 2198 GR EPEMIOLOGICAL STUDY ON DISORDERS OF CONSCIOUSNESS: ORGANIZATIONAL AND CARE MODELS IN ITALY. ESODOC in Italy 22 clinico assistenziale Healthcare Delivery and Methodologies , GR Are dually diagnosed patients more deprived than their single diagnosis counterpart? A cross sectional study in Italian Mental Health Care Trusts 22 clinico assistenziale Healthcare Delivery and Methodologies , GR Autophagy in human neuronal ceroid lipofuscinosis: a life saver or a death partner? 22 biomedica Brain Disorders and RF Erythropoietin in ALS: a study of dose finding, safety, and biological activity 22 clinico assistenziale Brain Disorders and , , RF Emerging risk prioritization in nursery and primary school catering: exposure evaluation, risk management and communication 22 biomedica Veterinary Food Safety FOSA , GR Hypoglycemia mediated brain injury: new pharmacological approaches 22 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Intrauterine growth restriction, oxidative stress and neurodevelopmental outcomes 22 biomedica Biobehavioral and Behavioral Processes , RF A novel global approach to face Mycobacterium bovis tuberculosis in man and animals today 22 biomedica Veterinary Animal Health ANHE 2206 RF IS HIGH ORAL DOSE L ARGININE SUPPLEMENTATION EFFECTIVE IN LEUKOARAIOSIS? A PRELIMINARY HOSPITAL BASED STUDY 22 clinico assistenziale Brain Disorders and ,00 Pagina 194 di 244

195 2207 GR Antitumoral effect of 3 O methylfunicone (OMF) from Penicillium pinophilum in in vitro model of melanoma and in animals. Effect of OMF combined with traditional chemiotherapy 22 biomedica Oncology 1 Basic , RF A proteomic approach to search potential biomarkers useful in colon cancer diagnosis 22 biomedica Oncology 1 Basic , GR Define the role of calcineurin/nuclear factor of activated T cells (NFAT) pathway activation in leukemogenesis, in particular to identify key regulators and new calcineurin substrates that could have an important role in tumor development and could be pot 22,17 biomedica Oncology 1 Basic , GR PROMISES study: Multicenter project Sleep and Heart Failure 22,25 clinico assistenziale Cardiovascular and , GR Role of environmental contaminants and eating habits as carcinogenetic cofactors influencing the risk of developing hepatocellular carcinoma in patients with HCVrelated liver cirrhosis 22,25 biomedica Risk, Prevention and Health Behavior , RF FACTORS ASSOCIATED WITH RECURRENCE OF UPPER RESPIRATORY TRACT INFECTION IN CHILDREN AT RISK (1 6 YEARS OLD): A COHORT STUDY 22,25 clinico assistenziale Infectious Diseases and Microbiology , RF Nuclear Magnetic Resonance Metabolomics as innovative diagnostic approach to Alzheimer's Disease 22,25 biomedica Brain Disorders and , GR Effect of the C1584G polymorphism of CYP2D6 on the efficacy of galantamine in patients with Alzheimer disease. 22,25 clinico assistenziale Genes, Genomes and , RF Fertility preservation in breast cancer patients: The evaluation of two ovarian tissue freezing techniques 22,34 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Characterization of mesenchymal stem cells able to participate in liver regeneration and development of a reproducible clinical protocol of stem cell transplantation in patients with chronic liver diseases 22,34 biomedica Digestive, Kidney and Urological Systems 2217 RF Metabolic syndrome and cardiovascular risk: identification of new gender associated risk factors 22,34 biomedica Cardiovascular and ,00 Pagina 195 di 244

196 2218 RF The role of retrograde perfusion to reduce ischemic reperfusion injury in double lung transplantation: a prospective randomized clinical study. 22,34 clinico assistenziale Cardiovascular and , GR Modulation of gene expression after GM SCF signaling reactivation in Pulmonary Alveolar Proteinosis. 22,34 biomedica Genes, Genomes and , GR Sleep related risk factors for postpartum depression 22,5 clinico assistenziale Risk, Prevention and Health Behavior , RF Exploiting the tumor microenvironment for the identification of mechanisms of induced resistance to paclitaxel and anti VEGF therapy in solid tumors as rationale for combination therapy. 22,5 biomedica Oncology 1 Basic , GR Phenotypic, Neurocognitive, Genetic and Surgical Characterization of Hypoplastic Left Heart Syndrome (HLHS) 22,5 biomedica Cardiovascular and , GR Regeneration of neuronal activity via multi walled carbon nanotubes 22,5 biomedica Bioengineering Sciences and Technologies , GR Novel bioactive nanostructured systems for gene therapy and vaccine development 22,5 biomedica Immunology , GR The Influence of Acetabular Labrum on Hip Joint Stability: a Biomechanical Analysis 22,5 biomedica Bioengineering Sciences and Technologies , GR Molecular and expression analysis of LKB1 in prostate cancer 22,5 biomedica Oncology 1 Basic , GR Immune and metabolic control of cancer growth: a novel biological system to study the immunotherapeutic role of leptin in cancer 22,5 biomedica Immunology 2228 GR Successful aging: definition and validation of a multidimensional model. 22,5 clinico assistenziale Population Sciences and Epidemiology , GR Effect of a new isoform of Superoxide Dismutase in the prevention and treatment of Malaria, prospectus of a new therapy methodology 22,5 clinico assistenziale Infectious Diseases and Microbiology , GR of alcohol dependence and depressive disorders: towards ad hoc therapy 22,5 biomedica Genes, Genomes and Pagina 196 di 244

197 2231 GR Evaluation of digital images acquired by computed tomography and magnetic resonance in virtual autopsy: new knowledge by the observation of a sample 22,5 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Identification of genetic markers of neoplastic progression in IBD 22,5 clinico assistenziale Oncology 2 Clinical , GR Arginine metabolites in the pathogenesis of Chronic Obstructive Pulmonary Disease (COPD): new insights into the identification of biomarkers of susceptibility and progression of the disease. 22,5 biomedica Cardiovascular and , GR CAREMORE LUNG: a population based study on lung cancer from tobacco to rehabilitation 22,5 clinico assistenziale Population Sciences and Epidemiology , GR Set your movements free! Expectation induced enhancement of motor recovery 22,5 biomedica Biobehavioral and Behavioral Processes , GR Emotional mechanisms in Williams Sindrome investigated by a multidisciplinary approach. Neuropsychological, neurophysiologic, functional neuroimaging, and neurobehavioral studies. 22,5 clinico assistenziale Brain Disorders and , GR INVESTIGATING MOLECULAR EPEMIOLOGY AND GENOMIC DIVERSITY OF BACILLUS ANTHRACIS IN ITALY BY WHOLE GENOME SNP ANALYSIS AND MLVA 22,5 biomedica Veterinary Animal Health ANHE , GR Alterations of bone mineral metabolism in young women with chronic bowel diseases. The pathogenetic role of serotonin and cytokines and the influence of nutritional and vitamin D deficiencies. 22,5 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Reperfusion injury after cerebral ischemia treated with thrombolysis: an in vivo study using biological and neuro imaging markers 22,5 clinico assistenziale Brain Disorders and , RF Genetic determinants of left ventricular hypertrophy 22,5 clinico assistenziale Cardiovascular and GR Food safety: emergence of vancomycin resistant Staphylococcus aureus (VRSA) 22,5 biomedica Veterinary Food Safety FOSA , ,00 Pagina 197 di 244

198 2242 RF Analysis of the pathogenetic mechanisms underlying Mental Retardation: identification of prognostic factors and therapeutic targets 22,5 biomedica Brain Disorders and 2243 GR The Impact of Pulmonary Rehabilitation on Exertional Dyspnea in patients with Mild Chronic Obstructive Pulmonary Disease 22,5 clinico assistenziale Cardiovascular and , GR In vitro effects of hypoxia on murine osteocytes 22,5 biomedica Cell Biology , GR Adoptive Immunotherapy Strategies for Relapsed or Metastatic Bone Sarcomas: Preclinical models and Clinical Applications. 22,5 clinico assistenziale Immunology , RF Bone mineral and body composition analyses in infants with different intrauterine growth: early detection of alterations for an effective prevention of osteoporosis and metabolic disturbances. 22,5 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Modulators of the mtor pathway in sarcomas: a genetic RNAi approach 22,5 biomedica Oncology 1 Basic GR Understanding the role of L arginine metabolism in mammary carcinogenesis 22,6 biomedica Oncology 1 Basic , , RF FETAL ALCOHOL SYNDROME: THE DAMAGE ASSOCIATED WITH PRENATAL ALCOHOL EXPOSURE IN HUMANS AND IN AN ANIMAL MODEL 22,67 biomedica Integrative, Functional, and Cognitive Neuroscience , GR In vivo silencing of autophagic genes (Atg) by electroporation mediated transfection. A promising target therapy to improve chemosensitivity of tumour cells. 22,67 biomedica Oncology 1 Basic , RF Morbid Obesity. Prospective cohort study with analysis of treatment (medical or surgical), evaluation of outcome predictors and assessment of cardiovascular and liver disease risk. 22,67 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR RECONSTRUCTION OF EPEMIOLOGICAL LINKS AND TRANSMISSION OF PRIMARY RESISTANCE TO ANTIRETROVIRALS IN A DENSE HIV 1 POPULATION BY MOLECULAR PHYLODYNAMICS 22,75 biomedica AS and Related Research ,00 Pagina 198 di 244

199 2253 GR ACUTE INFLAMMATORY LEUKOENCEPHALOPATHIES OF VARIOUS ORIGIN: MULTISCIPLINARY STUDY ON AETIOPATHOGENETIC MECHANISMS AND ENTIFICATION OF DISEASE MARKERS 22,75 biomedica Brain Disorders and , GR The emerging problem of malignant mesothelioma in Emilia Romagna region: observational increasing incidence and need for identification of therapy related predictive markers 22,75 biomedica Oncology 1 Basic , RF Construction of an ICT setting for the facilitation of home functional rehabilitation through motor cognitive therapies 22,75 clinico assistenziale Healthcare Delivery and Methodologies , GR PSY GE (Psychology and genetics): A study on the relationship between Psychoeducation, SNPs, side effects and adherence to improve compliance, quality of life and health in People with schizophrenia 22,75 clinico assistenziale Brain Disorders and , GR Development of new techniques to investigate brain iron from imaging data 22,75 biomedica Brain Disorders and , RF Regional based registry of Pervasive Developmental Disorders in Italy: prevalence estimation of autism and survey of diagnostic tools and health services 22,75 clinico assistenziale Brain Disorders and , RF Designing an antibody based therapy for an effective eradication of Ewing sarcoma. Selective delivery of radionuclide and immunostimulatory cytokines to tumor cells using a human monoclonal antibody in single chain fragment variable (scfv) format showi 22,75 biomedica Oncology 2 Clinical 2260 RF NATURAL PRODUCTS WITH ANTI MICROBIAL ACTIVITY AND THEIR INTERACTION WITH THE IMMUNE SYSTEM: IN VITRO AND IN VIVO STUDIES FOR THE EVALUATION OF NEW THERAPEUTICAL TOOLS 22,75 biomedica Immunology , RF Evaluation of an innovative rehabilitative approach in a multimodal setting for NSCLC post surgery patients. 22,75 clinico assistenziale Cardiovascular and , GR Development of an optical diagnostic tool set based on Raman light scattering: from chemical imaging of tissue sections to real time tissue analysis in the surgical operation theatre 22,84 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering ,00 Pagina 199 di 244

200 2263 RF Harmonization and standardization of biobanking activities: definition of guidelines and operating procedures 22,84 biomedica Bioengineering Sciences and Technologies , RF Relationship between modulation of frataxin function and iron independent oxidative stress related to the cytosolic phospholipase A2/arachidonic acid pathway. 23 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Does "emotional" rehabilitation affect expression/recognition of emotional facial expressions and EEG markers (alpha rhythms, event related potentials) in mild cognitive impairment patients with depression? An innovative methodological approach based on s 23 clinico assistenziale Brain Disorders and , GR Effect of polyphenols rich extra virgin olive oil on childhood obesity: making the connection between inflammation and insulin resistance. 23 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR An innovative approach to the development and validation of Biomarkers of Autism: a challenge for diagnosis and follow up of children, contributing to understand the molecular mechanisms of the different clinical forms 23 clinico assistenziale Biobehavioral and Behavioral Processes , RF DEVELOPMENT OF FORMULATION OF ZOLEDRONIC AC ENCAPSULATED IN LIPOSOME: A NEW OPPORTUNITY AGAINST CANCER 23 biomedica Oncology 2 Clinical , GR Role of the Vascular Endothelial Growth Factor (VEGF) as predictor of failure of mechanical abrasion in treatment of primary spontaneous pnemothorax 23 clinico assistenziale Cardiovascular and , GR THE EFFICACY OF COGNITIVE REMEDIATION IN PSYCHIATRIC DISORDERS 23 clinico assistenziale Brain Disorders and , GR Induction of fetal haemoglobin in primary erythroid cells using new pharmacological agents: a model for the treatment of haemoglobinopathies 23 biomedica Vascular and Hematology , GR Development of an affinity based enrichment protocol for isolating subproteomes for diagnostic/prognostic and drug therapy evaluation purposes 23 biomedica Interdisciplinary Molecular Sciences and Training , RF PHASE II PROSPECTIVE TRIAL: HIFU FOCAL THERAPY FOR LOCALISED PROSTATE CANCER 23 clinico assistenziale Digestive, Kidney and Urological Systems ,00 Pagina 200 di 244

201 2274 GR CLINICAL AND INSTRUMENTAL EVALUATION OF A LOCAL INTRAOPERATIVE DRUG THERAPY TO IMPROVE PRIMARY STABILITY IN TOTAL KNEE REPLACEMENT 23 clinico assistenziale Musculoskeletal, Oral and Skin Sciences , GR RNA Seq transcriptome analysis of Mid2 null and wild type murine embryonic Heart and Thymus. 23 biomedica Biology of Development and Aging , RF THERAPEUTIC POTENTIAL OF MULTIPOTENT MESENCHYMAL STEM CELLS (MSCs) IN CROHN'S DISEASE, A TYPICAL PRE CANCEROUS CHRONIC INFLAMMATION WITH INCREASING INCENCE: Evaluation of MSCs regulatory role on immune cells in vivo and ex vivo. 23 biomedica Digestive, Kidney and Urological Systems , RF Primary care practice based Emergency Department outpatient clinic: working at the interface between hospital and community. 23 clinico assistenziale Healthcare Delivery and Methodologies , RF Standardization of molecular methods to genetic individuation of ovine and bovine subjects belonging to typical italian species. Study of the microsatellite patterns, data analysis for forensic and parentage verification approach. 23 biomedica Veterinary Food Safety FOSA , GR Iodinated contrast media acute renal failure: Molecular mechanisms of cell damage and identification of novel early biomarkers and new potential therapeutic molecules. 23 biomedica Digestive, Kidney and Urological Systems , GR Effect of electromagnetic field (EMFs) on the Alzheimer disease progression: a long term exposition study. 23 clinico assistenziale Brain Disorders and , GR THE IMPACT OF DYSREGULATED RAS SIGNALING IN COGNITIVE FUNCTION 23 biomedica Molecular, Cellular, and Developmental Neuroscience GR Role of CLIC1 in glioblastoma derived cancer stem cells 23 biomedica Oncology 1 Basic GR Chronic kidney disease and the cardiovascular risk in Italy 23 clinico assistenziale Population Sciences and Epidemiology , , GR Functional study and detailed molecular analysis of the ABCB4 gene in human liver diseases with and without HCV infection characterized by rapid and slow hepatic fibrosis 23 biomedica Digestive, Kidney and Urological Systems ,00 Pagina 201 di 244

202 2285 GR BIO INSPIRED, SUPER PARAMAGNETIC NANOPARTICLES FOR TARGETED THERAGNOSTIC APPLICATIONS IN MELANOMA 23 biomedica Bioengineering Sciences and Technologies , RF Anaesthesia opioid free and perioperative management for prevention of postoperative ileus 23 clinico assistenziale Digestive, Kidney and Urological Systems , RF Molecular mechanisms of neurogenesis alterations in mood related disorders. BDNF as a therapeutic target? 23 biomedica Molecular, Cellular, and Developmental Neuroscience , GR AUTOPHAGY AND APOPTOSIS AS KEY REGULATORS OF MUSCLE ATROPHY IN MYOTONIC DYSTROPHIES AND LIMB GIRDLE MUSCULAR DYSTROPHY. 23 clinico assistenziale Musculoskeletal, Oral and Skin Sciences , GR Genome wide association study (GWAS) and detection of novel genetic loci involved in the carcinogenesis of differentiated thyroid carcinoma (DTC). 23 biomedica Genes, Genomes and , GR A Comprehensive Approach for the Identification of Learning Disabilities 23 clinico assistenziale Emerging Technologies and Training in Neurosciences , GR Disorders on mitochondrial DNA synthesis and maintenance: clinical, histopathological and genetic study in a heterogeneous population with mitochondrial disorders 23 clinico assistenziale Genes, Genomes and , RF Acute and delayed adverse Health Effects of Airborne Particle Pollution (HEAPP): a mechanistic study of the biological effects of particles size and chemistry nested within an epidemiological cohort study among traffic police officer 23 clinico assistenziale Population Sciences and Epidemiology , GR Post translational modification of frataxin. Role in frataxin maturation and functions. New insights for the pathogenesis of the Friedreich s Ataxia. 23 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Strategies for the identification of colorectal cancer (CRC) high risk subjects and development of tailored clinical and molecular surveillance programs 23 biomedica Oncology 2 Clinical , GR Reward based recovery of attentional mechanisms in stroke and traumatic brain injury patients: An integrated behavioral and rtms approach 23 clinico assistenziale Brain Disorders and ,00 Pagina 202 di 244

203 2296 GR Tumor initiating colon cancer cells in human liver metastasis: technological assessment and clinical relevance 23 biomedica Oncology 1 Basic , GR Modulation of Ischemia/reperfusion damage during human liver transplantation using anti lymphocyte T polyclonal antibodies 23 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , RF RAGE/insulin signalling interactions: new pathway linking inflammation to insulin resistance 23 biomedica Cell Biology , RF Modulation of genes G protein signaling modulator in vascular endothelium regulating the mechanism of vasodilatation: a role in arterial hypertension 23 biomedica Vascular and Hematology , RF Triage test combined with the p16ink4a Ki 67 in screening cervical cancer with HPVDNA TEST 23 biomedica Risk, Prevention and Health Behavior , RF Innovative molecular imaging to assess the tumorigenic potential of feline mammary carcinoma stem cells 23 biomedica Veterinary Animal Health ANHE 2302 GR Congenital hyperinsulinism of infancy: clinical and metabolic evaluation, genetic characterization, identification of candidate genes, national registry and role of hyperinsulinemic hypoglycemia in the Apparent Life Threatening Events (ALTE) and Sudden In 23,17 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Neurofunctional evaluation of low level consciousness patients 23,17 clinico assistenziale Brain Disorders and , RF Philadelphia negative Myeloproliferative Neoplasms: new molecular approaches for translational research and patients clinical management through the creation of a regional network. 23,17 biomedica Oncology 1 Basic , RF Implementation of a multidisciplinary network for the prevention, early diagnosis and clinical care of vertically transmitted infections 23,25 clinico assistenziale Healthcare Delivery and Methodologies , GR Arrhythmogenic Right Ventricular Cardiomyopathy: In The Research Of Clinical And Molecular Prognostic Markers 23,25 biomedica Cardiovascular and ,30 Pagina 203 di 244

204 GR Modeling progression of colorectal cancer via pathway dependencies 23,25 biomedica Genes, Genomes and GR Investigating the role of placebo and nocebo effects in migraine 23,25 clinico assistenziale Brain Disorders and , , GR Characterization of Transcranial Magnetic Stimulation (TMS) response in patients with Major Depression: the influence of genetic and epigenetic patterns 23,25 clinico assistenziale Brain Disorders and , GR THE VENOUS OXYGEN SATURATION (VOXSAT) PEDIATRIC CARDIAC SURGERY TRIAL 23,25 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , RF DEVELOPMENT OF AN INTEGRATED BIOSTATISTICS AND BIOINFORMATICS FRAMEWORK FOR CLINICAL TRANSLATION AND EVALUATION OF NEW BIOMARKER TECHNOLOGIES 23,25 clinico assistenziale Oncology 2 Clinical , GR TREATMENT OF PERITONEAL CARCINOMATOSIS WITH CYTOREDUCTIVE SURGERY AND HYPERTHERMIC INTRAPERITONEAL CHEMOTHERAPY (HIPEC): STUDY OF FACTORS ASSOCIATED WITH THE THERAPEUTIC RESPONSE. 23,25 biomedica Oncology 2 Clinical , RF Study of the risks related to Listeria monocytogenes in dairy products: detection, molecular typing and use of bacteriocin producing Lactic Acid Bacteria to reduce the contamination. 23,34 biomedica Veterinary Food Safety FOSA , GR Pathogenicity and clincal impact of emerging pathogens 23,34 biomedica Infectious Diseases and Microbiology 2315 GR Artificial Neural Network in development of Innovative diagnostic systems for Carotid Atherosclerosis: the ANN ICA study 23,34 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , RF The role of semaphorins in the progression of chronic liver injury: from fibrosis to hepatocellular carcinoma 23,34 biomedica Oncology 1 Basic , RF Outcome indicators in pediatric hospital care 23,34 clinico assistenziale Healthcare Delivery and Methodologies ,00 Pagina 204 di 244

205 2318 RF Farm Community model and Autism in adolescent and young adult subjects 23,5 clinico assistenziale Healthcare Delivery and Methodologies , RF Development of an index, registry and research based networking for pediatric biobanks 23,5 biomedica Genes, Genomes and , RF Health Technology Assessment (HTA) of Amplatzer Cardiac Plug (ACP) for Left Atrial Appendage Embolization in patients with non valvular Atrial Fibrillation (AF) with High Risk for Oral Anticoagulant Therapy (CHADS2 score). 23,5 clinico assistenziale Healthcare Delivery and Methodologies , GR Understanding and translating into the clinical approach the underlying mechanisms of non conventional medicine in the therapy of pain: the western scientific approach in the service of eastern medicine (EASTWESTHOSTILE to PAIN) 23,5 clinico assistenziale Emerging Technologies and Training in Neurosciences 0, RF Three key drugs in newborns: a novel approach for micro dosing by means of advanced mass spectrometry techniques 23,5 clinico assistenziale Cardiovascular and , GR Understanding the physiopathology of endogenous stem cells to boost their efficacy as endogenous therapeutics for muscle diseases 23,5 biomedica Musculoskeletal, Oral and Skin Sciences , GR Implementation of an organizational model in the care pathways of people with eating disorders: filters definition and operational policy 23,5 clinico assistenziale Healthcare Delivery and Methodologies , RF Chemical contamination of foods and the Italian consumer's risk assessment through the ONR OICA database 23,5 biomedica Veterinary Food Safety FOSA , GR The role of apoptosis and autophagy in the pathogenesis and progression of Rheumatoid Arthritis. 23,5 biomedica Immunology , RF SYNBIO TRIAL: RANDOMIZED CONTROLLED TRIAL ON THE USE OF SYNTHETIC VS BIOSYNTHETIC PATCH FOR THE TREATMENT OF CONGENITAL DIAPHRAGMATIC HERNIA 23,5 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , GR An Open label, Single Center, Randomized, 2 arm Study to Investigate the Impact of Serum Free Light Chain Removal by High Cutoff Hemodialysis versus Conventional Plasma Exchange in Acute Renal Failure due to Cast Nephropathy 23,5 clinico assistenziale Digestive, Kidney and Urological Systems ,00 Pagina 205 di 244

206 2329 GR A first level screening test for 22q11.2 microalterations detection in patients with congenital heart disease 23,5 biomedica Genes, Genomes and , GR The role of Osteopontin and SPARC towards development of androgenindependent prostate cancer 23,5 biomedica Oncology 1 Basic , GR Pilot study of Lokomat versus manual assisted with body weight support on the treadmill training for gait recovery in Parkinsonian patients. 23,5 clinico assistenziale Brain Disorders and , RF MOLECULAR MECHANISMS OF CHEMOSENSIBILIZATION TO THE ACTION OF CISPLATIN IN MESOTHELIOMA THERAPY 23,5 biomedica Oncology 1 Basic , GR Inhibition of phosphatidylcholine specific phospholipase C as a new strategy to counteract tumor promoting inflammation 23,67 biomedica Oncology 1 Basic , GR Two hits one goal: lentiviral synapsin I gene delivery and ATF4/CREB 2 gene silencing. An integrative approach to counteract the alpha synuclein induced neuronal derangement in Parkinson disease 23,67 biomedica Brain Disorders and , RF Phenotypic and molecular characterization aimed at chemosensitization of hormone independent prostate cancer models 23,67 biomedica Oncology 1 Basic , RF New prognostic tools of cardiovascular events in patients undergone to prosthetic heart valve implantation 23,67 biomedica Cardiovascular and , RF Nanomedicine applied to cerebral ischemia 23,67 biomedica Bioengineering Sciences and Technologies RF Characterization of autophagy role in HIV infected LTNP 23,75 biomedica AS and Related Research , , GR PRO SHOULD Project for a comprehensive assessment of shoulder function outcome measures: development of a new three dimensional (3D) model, for research including technology, using an optoelectronic based motion analysis system as gold standard for identi 23,75 clinico assistenziale Musculoskeletal, Oral and Skin Sciences , RF Innovative approaches for disease management of difficult to treat tuberculosis patients in a low burden context 23,75 clinico assistenziale Infectious Diseases and Microbiology ,00 Pagina 206 di 244

207 2341 RF Evaluation of the inhibitory effect of specific blocking antibody and the modulatory action of high molecular weight Hyaluronan of CD44 and Toll like receptors on diabetic complications in congenic diabetic mice and streptozotocininduced diabetes in mice 23,75 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Efficacy of transcranial Direct Current Stimulation (tdcs) in the treatment of paediatric pharmaco resistant focal epilepsy 23,75 biomedica Brain Disorders and , RF Role of master transcription factors in regulating tumor microenvironment interaction and survival programs in human melanoma 23,84 biomedica Oncology 1 Basic , GR Generation of neuronal cellular models from skin fibroblasts to study the relevance of iron homeostasis alterations in the pathogenesis of Pantothenate Kinase Associated Neurodegeneration. 24 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Diagnosis of attention deficit/hyperactivity disorder (ADHD) in children by quantitative EEG and transcranial magnetic stimulation markers. 24 biomedica Biobehavioral and Behavioral Processes , RF Trans Oral Robotic versus Open Tongue Base Reduction & SupraGlottoPlasty for adult Obstructive Sleep Apnea Hypopnea Syndrome :A Randomised Controlled Trial 24 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , GR Molecular markers for prediction or early diagnosis of colorectal cancer 24 biomedica Population Sciences and Epidemiology , GR Prognostic biomarkers for the level of circulating Endothelial Progenitor Cells (EPCs) in a cohort of healthy donors, pre diabetic and type 2 diabetic patients. 24 biomedica Genes, Genomes and , GR Relationship between mitochondrial genetic load and visual system abnormalities in migraine 24 clinico assistenziale Brain Disorders and , GR Volumetric breast density by MRI as a predictor of breast cancer: a 6 year prospective study 24 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , GR Added value of MR Spectroscopy in the screening, diagnosis and follow up of Cardiac involvement in patients with Anderson Fabry disease 24 clinico assistenziale Cardiovascular and ,00 Pagina 207 di 244

208 2352 GR Molecular analysis of LTBP2, the new gene associated with Primay Congenital Glaucoma, in Italian patients without CYP1B1 mutations. 24 biomedica Genes, Genomes and , RF Molecular imprinting on electrospun scaffolds for cardiovascular disease 24 biomedica Cardiovascular and , GR Identification of Novel Akt Substrates and Binding Partners During Myogenesis by a Functional Proteomic Approach: Benefits for Diagnosis and Symptoms Attenuation in Primary and Secondary Myopathies. 24 biomedica Musculoskeletal, Oral and Skin Sciences , RF Genotypes of Toxoplasma gondii present in Central Italy, their pathogeneticity and transmission among wildlife, livestock and humans. Are the ectoparasites an additional natural source of infection? 24 biomedica Veterinary Animal Health ANHE , GR Identification of novel prognostic factors and potential therapeutic targets for post operative atrial fibrillation 24 biomedica Cardiovascular and , GR Efficacy of psychological support interventions tailored to caregivers of patients with stroke, heart failure or chronic obstructive pulmonary disease undergoing a rehabilitation program: a pilot study. 24 clinico assistenziale Risk, Prevention and Health Behavior , GR Health risk assessment for Lyme disease and TBE in Italy and possible introduction of CCHF 24 biomedica Infectious Diseases and Microbiology , GR From Aß deposition to synaptic dysfunction in the TgCRND8 mouse: in vitro and in vivo studies of the molecular, cellular and functional alterations 24 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Integration of DCE MRI, DWI and MRSI for early evaluation of response to neoadjuvant therapy in locally advanced breast cancer patients. 24 biomedica Bioengineering Sciences and Technologies 2361 RF Stem cells derived from lipoaspirate of transplanted patients: future for tissues regeneration 24 biomedica Biology of Development and Aging , GR Identification and characterization of putative tumour suppressor mirnas for replacement therapy 24 biomedica Oncology 2 Clinical ,00 Pagina 208 di 244

209 2363 RF Role of anti lymphocytes autoantibodies in autoimmunity and in lymphomagenesis 24 biomedica Immunology , RF HEALTH AND SAFETY OF WORKERS RELATED TO AGEING AND CHANGE IN THE PRODUCTIVE SYSTEMS AND SOCIAL POLICIES 24 clinico assistenziale Population Sciences and Epidemiology , GR Liposomal drug delivery system in the treatment of Pertiodontal diseases 24 biomedica Infectious Diseases and Microbiology , GR Interaction between genetic predisposition and inflammation in sporadic amyotrophic lateral sclerosis : identification of novel therapeutic targets to reduce motor neuron vulnerability 24 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Rejuvenating Cardiac Stem Cells 24 biomedica Cardiovascular and , GR Assessment of the hygienic and health status of fish and molluscs bred in aquaculture plants counted in Campania Region (Italy), under the microbiological, parasitological and chemical toxicological aspects. 24 biomedica Veterinary Food Safety FOSA , RF Assessing the effect of intensive neurorehabilitation treatment (IRT) on neurotrophic factors production and dopamine transmission in patients with newly diagnosed Parkinson s disease 24 clinico assistenziale Brain Disorders and , GR Layer specific genes as neuronal markers for diagnosis and pathogenesis of malformations of cortical development: a combined study on human and animal model 24 biomedica Brain Disorders and , RF S. aureus and L. monocytogenes in food and environment: new methods to assess biofilm formation in order to verify efficacy of sanitizing agents to reach a high hygiene level in food producing processes and risk analysis on cross contamination with comm 24 biomedica Veterinary Food Safety FOSA 2372 RF Role of respiratory viral infections in asthma exacerbations: clinical and therapeutic implications. 24 clinico assistenziale Infectious Diseases and Microbiology , RF Autism Spectrum Disorder: a new approach to the management of Rett syndrome based on administration of omega 3 LC PUFAs 24 clinico assistenziale Biobehavioral and Behavioral Processes ,00 Pagina 209 di 244

210 2374 RF Text Mining and the Public Health System. Mining Public Health Databases to Enhance the Quality of Health Care 24 clinico assistenziale Healthcare Delivery and Methodologies , GR Development of efficient gene expression and protein secretion system in nonpathogenic gram positive Lactobacillus for Canine parvovirus infection in puppies 24 biomedica Veterinary Animal Health ANHE , RF Developing therapeutic strategies that support astrocyte function as new avenues in the treatment of neurodegenerative diseases: focus on Parkinson's disease 24 biomedica Brain Disorders and , RF Study of role of the Aryl Hydrocarbon Receptor (AHR) in the activation of apoptosis in cancer cells 24 biomedica Oncology 2 Clinical , RF Megalencephalic leukoencephalopathy with subcortical cysts: new insights on MLC1 function and therapeutic developments. 24 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Realization of a Bio Bank for Rare Ocular Disease 24,17 biomedica Cell Biology 2380 RF CRYPTOgeNetic Ischemic stroke and atrial Tachyarrhythmic Events (CRYPTONITE) 24,17 clinico assistenziale Cardiovascular and , RF Health and environmental issues of asbestos fibres in natural and human context. Biological studies by in vitro screening for mineral pathogenicity after mineralogical characterization of Ca Fe Mg amphiboles and thermal transformed cement asbestos materia 24,17 biomedica Oncology 1 Basic , RF Role of immune inflammation in the normal and pathological ageing. 24,17 biomedica Biology of Development and Aging GR screening programs of dysphagia 24,25 clinico assistenziale Biobehavioral and Behavioral Processes RF Action and object observation treatment in rehabilitation of cerebral palsy 24,25 clinico assistenziale Brain Disorders and , , , GR Novel global measures for an eearly and safe use of antibiotic therapy in severe infections in ICU with respect of to emerging antimicrobial resistance patterns: development of a computer decision support system for Italian Intensive Care Units. 24,25 clinico assistenziale Infectious Diseases and Microbiology ,00 Pagina 210 di 244

211 2386 RF Environmental exposure of the Italian population to toxicants and/or endocrine disrupters: Identification and development of gene expression biomarkers. 24,25 biomedica Genes, Genomes and 2387 RF WAKE UP ISCHEMIC STROKE: CLINICAL, NEUROSONOLOGICAL AND RADIOLOGICAL FEATURES, INCLUDING PERFUSIONAL CT 24,34 clinico assistenziale Brain Disorders and , RF Role of the nociceptin/orphanin FQ NOP receptor system in immune and gliamediated regulation of neuronal functions: search of novel drugs for neurophatic pain control 24,34 biomedica Integrative, Functional, and Cognitive Neuroscience , GR Repeated influenza A infections as a risk factor for the development of neurodegenerative diseases, including Parkinson s disease 24,5 biomedica Infectious Diseases and Microbiology , GR OFF PUMP, BEATING HEART, MITRAL VALVE REPAIR 24,5 clinico assistenziale Cardiovascular and , GR Maspin expression and function in melanoma: evaluation of maspin as new prognostic marker and a therapeutic target for melanoma patients 24,5 biomedica Oncology 2 Clinical , GR Identification of metabolic pathways and genes affected by FUS RNA binding protein dysfunction in Amyotrophic Lateral Sclerosis 24,5 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Telemedicine based management model for Amyotrophic Lateral Sclerosis patients 24,5 clinico assistenziale Healthcare Delivery and Methodologies GR A functional study on implications of PPAR gene polymorphisms in AD 24,5 biomedica Genes, Genomes and , , RF Spinal and supraspinal functional, biomolecular and morphofunctional changes in a model of neuropathic pain in the mouse: recovery perspectives by transplantation of human mesenchymal stem cells in the prelimbic cortex. 24,5 biomedica Biobehavioral and Behavioral Processes , GR Identification of genetic variants associated with atherothrombotic vascular risk in cardiosurgery patients 24,5 biomedica Risk, Prevention and Health Behavior , RF Farmed mussels (Mytilus galloprovincialis) diseases as environmental biomarkers. 24,5 biomedica Veterinary Food Safety FOSA Pagina 211 di 244

212 2398 RF Innovative immunotherapeutic protocols for the treatment of HER 2+ cancer patients 24,5 biomedica Oncology 2 Clinical , GR Evaluation of large scale brain networks connectivity in mild cognitive impairment as a marker to track Alzheimer s disease progression 24,5 biomedica Brain Disorders and 2400 GR Marteilia refringens biomonitor in captive and cultured mussel (Mytilus galloprovincialis) population in Campania region: etiology, phases of the infection, temporal and spatial variability in prevalence 24,5 biomedica Veterinary Animal Health ANHE 2401 GR Walking through atherosclerosis.physical training in peripheral arterial disease: effects of an intensive treatment protocol on walking performance, redox state, inflammation, platelets and endothelial function. 24,5 clinico assistenziale Vascular and Hematology , GR Strategies of colorectal cancer screening: virtual colonoscopy versus fecal occult blood test 24,5 clinico assistenziale Digestive, Kidney and Urological Systems 2403 GR CARDIAC STEM CELLS: FROM CELL ISOLATION, THROUGH DESIGNING A BIODEGRADABLE SCAFFOLD FOR STEM CELL THERAPY, TO A NEW SURGICAL APPROACH 24,5 biomedica Cardiovascular and , RF INNOVATIVE TOOLS FOR THE STUDY, DIAGNOSIS AND TREATMENT OF NEUROVASCULAR DISEASE AND COGNITIVE IMPAIRMENT 24,5 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , GR New diagnostic approaches for identification of known and new viruses in cell cultures and biological samples 24,5 clinico assistenziale Healthcare Delivery and Methodologies , GR THE NETWORK OF MOLECULAR INTERACTIONS UNDERLYING LIVER REGENERATION: A NEW ROAD FOR THE SUCCESS OF LIVER CELL TRANSPLANTATION. 24,5 biomedica Digestive, Kidney and Urological Systems , RF Welfare assessment of horses on farm and during transport 24,5 biomedica Veterinary Animal welfare ANWE GR END OF LIFE DECISION STUDY ( E.L.D.Y. PROJECT) 24,5 clinico assistenziale Population Sciences and Epidemiology , ,00 Pagina 212 di 244

213 2409 GR Radiotherapy Response prediction in cancer: from the genetic code into the clinics 24,5 biomedica Oncology 2 Clinical , GR OBESITY IN PREGNANCY: OXATIVE AND NITROSATIVE STRESS IN PLATELETS AND LIPOPROTEINS 24,5 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Inflammation, angiogenesis and microrna in malignant mesothelioma. 24,5 biomedica Oncology 1 Basic , RF Molecular signature of circulating osteogenic stem cells: clinical relevance for bone regenerative medicine 24,5 biomedica Musculoskeletal, Oral and Skin Sciences , RF A neuroscientific study of the factors leading to cognitive decline, and the treatment of cognitive symptoms following stroke 24,5 clinico assistenziale Brain Disorders and , RF Development and validation of rapid tools to diagnose high impact emerging viral pathogens 24,5 clinico assistenziale Infectious Diseases and Microbiology 2415 RF Vascular compliance before and after brachial ischemia in small for gestationalage children adolescents 24,5 clinico assistenziale Risk, Prevention and Health Behavior , RF PERSONAL, MOBILE, REUSABLE AND WIRELESS SYSTEM FOR NURSING SUPPORT DETECTING AND SIGNALING BIOMEDICAL MEASUREMENTS AND POTENTIALLY CRITICAL CONDITIONS ORIENTED TO A TIMELY INTERVETION FOR STAYING IN BED PATIENTS AND TO A BIOMEDICAL DATA BASE CREATION FOR 24,5 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , RF BIOINFORMATIC AND BIOENGINEERING ANALYSIS TO STUDY LATE ONSET EPILEPSY 24,67 biomedica Emerging Technologies and Training in Neurosciences , RF INVOLVEMENT OF mglu7 AND mglu8 RECEPTORS IN NEROPATHIC PAIN: THERAPUTIC PERSPECTIVES 24,67 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Evaluating the influence of genetic factors in the response to rotigotine in patients with Idiophatic Parkinson s Disease 24,75 biomedica Molecular, Cellular, and Developmental Neuroscience ,00 Pagina 213 di 244

214 2420 RF NEW PURINERGIC STRATEGIES TO IMPLEMENT ENDOGENOUS NEUROGENESIS AND RE MYELINATION IN THE REPAIR OF SPINAL CORD INJURY AND BRAIN ISCHEMIA 24,75 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Brain computer interfaces to support individual autonomy: transfer to the rehabilitation context 24,75 clinico assistenziale Emerging Technologies and Training in Neurosciences , RF Psychobiological predictors of treatment response in Panic Disorder and Obsessive Compulsive Disorder. 24,75 clinico assistenziale Biobehavioral and Behavioral Processes , RF Identification of genetic and epigenetic factors for patient tailored treatment in myelodysplastic syndromes and acute myeloid leukemia 24,75 biomedica Oncology 2 Clinical , GR A recessive form of Alzheimer disease (AD) associated with a novel APP variant with dominant negative effect on amyloidogenesis: deciphering the molecular mechanisms underlying the opposite effects of the A673V mutation in the homozygous or heterozygous s 24,84 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Functional and Structural neuroimaging markers for early diagnosis/prognosis of Alzheimer's disease as a function of Genetic risk factors 25 clinico assistenziale Brain Disorders and , RF Beyond classical neurotransmission: the potential role of novel neuromodulators in physiological and pathological brain functioning 25 biomedica Molecular, Cellular, and Developmental Neuroscience 2427 RF Mucosal innate immunity in early phases of HIV infection: role of activated gamma/delta T cells as adjuvants enhancing protective anti HIV response. 25 biomedica Immunology , GR Global Warming and health risk assessment: human and animal leishmaniasis infection is growing in Italy? 25 biomedica Veterinary Animal Health ANHE , RF Proteomic and biochemical characterization of osteoblast metabolism in Adolescent Idiopathic Scoliosis 25 biomedica Musculoskeletal, Oral and Skin Sciences , GR Genetic and pathological changes induced by toxic residues in ruminats milk and their effects on public health 25 biomedica Veterinary Food Safety FOSA ,00 Pagina 214 di 244

215 2431 RF Assessment of resistance to infections and of the effectiveness of immunomodulatory treatments to reduce the need for antimicrobials in periparturient, high yielding dairy cattle 25 biomedica Veterinary Animal Health ANHE , GR Obesity and cachexia in chronic heart failure insights into the interplay between metabolic changes, mechanisms of muscle wasting and exercise capacity 25 clinico assistenziale Cardiovascular and , GR The role of cathepsin B in the cannibalic behavior of metastatic melanoma cells 25 biomedica Oncology 1 Basic , RF IN VITRO PROPAGATION AND EXPANSION OF NORMAL ENDOTHELIAL PROGENITORS FROM BLOOD: A NEW TOOL FOR REGENERATIVE MEDICINE 25 biomedica Vascular and Hematology , GR Role of imaging in the evaluation of the natural history and of the efficacy of the anticancer treatment driven by nanoparticles in liver metastases of nude rats affected by colorectal carcinoma 25 biomedica Bioengineering Sciences and Technologies , RF Genetic upgrade of Emilia Romagna Bone Marrow Donor Registry 25 biomedica Genes, Genomes and , GR Fat tissue as source of cardiomyocytes: epigenetic and transcriptional characterization of adipose tissue derived stromal vascular fraction and of white mature adipocytes during cardiomyocyte differentiation 25 biomedica Cardiovascular and , GR Linear and non linear parameterization of EEG in patients affected by senile dementia and disorders of consciousness for diagnosis and prognosis purposes 25 biomedica Bioengineering Sciences and Technologies , GR Turning expression into advantage: a new tool for regulatory T cell therapy 25 biomedica Immunology , RF Immunologic investigations in Amyotrophic Lateral Sclerosis: disease improvements need a cross talk among basic genetic research and immunological clinical data. 25 biomedica Immunology , GR Successful Iloprost treatment and Metabolic Profile of critical Limb ischemia in Elderly patients (SIMPLE) 25 biomedica Vascular and Hematology , GR Endothelialization of biofunctionalized human cardiac valves by endothelial progenitor cells 25 biomedica Bioengineering Sciences and Technologies ,00 Pagina 215 di 244

216 2443 GR Study of regulatory regions of CFTR in cystic fibrosis patients bearing unknown mutations 25 biomedica Genes, Genomes and , RF Clinical and economic impact of Low Dose CT Coronary Angiography vs. Stress Imaging in the assessment of suspected Coronary Artery Disease:PARADISE Study 25 clinico assistenziale Cardiovascular and , RF Classe V beta tubulin expression as biomarker in solid tumors. 25 biomedica Oncology 1 Basic , GR Neuroinflammation in the pathogenesis of seizures and epilepsy: a nanomedicinal approach 25 biomedica Brain Disorders and 2447 GR Hospital based Stroke Registry in Modena Province 25 clinico assistenziale Population Sciences and Epidemiology , RF neurometabolic correlates of non pharmachological intervention in social phobic patients: through a neurobiological basis of attentional bias theory of social phobia 25 biomedica Brain Disorders and , GR NEW PERSPECTIVES IN OVARIAN CANCER DIAGNOSIS AND CLINICAL TREATMENT DEPICTING THE BIOLOGICAL PATHWAYS WITH A REDOX PROTEOMIC APPROACH 25 biomedica Oncology 1 Basic , RF GLUCOCORTICOS, OXATIVE STRESS AND CARDIOVASCULAR RISK IN HUMANS: EVALUATION OF HYPER AND HYPOCORTISOLEMIC STATES BEFORE AND AFTER REMISSION AND NEW POSSIBLE THERAPEUTIC STRATEGIES 25 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Biological characterization of Brain Tumor Initiating Cells and their treatmentresistance features. 25 biomedica Oncology 1 Basic , GR PHOSPHOPROTEOMIC PROFILING OF COLORECTAL CANCER LIVER METASTASIS FOR RESPONSE PREDICTION AND TREATMENT IMPROVEMENT 25 biomedica Oncology 2 Clinical , GR Congenital abnormalities of kidney and urinary tract: clinical and genetic study aimed to identify a proper work up for paediatric patients 25 biomedica Digestive, Kidney and Urological Systems , GR Innovative biomarkers in rheumatoid arthritis: cardiovascular risk scoring tools to promote a better management of cardiovascular disease in RA 25 biomedica Vascular and Hematology ,00 Pagina 216 di 244

217 2455 RF Detection and characterization of Coxiella burnetii in water buffalo (Bubalus bubalis) 25 clinico assistenziale Veterinary Animal Health ANHE , RF Monoclonal antibodies to external domains of the chemokine receptors CXCR4 and CCR5 to study structure and biology of the receptors during a mucosal inflammatory status 25 biomedica Immunology 2457 RF Identification of molecular targets shared by apoptosis and EMT pathways in cancer 25 biomedica Oncology 1 Basic , RF GENDER AND AGE RELATED DIFFERENCES IN HUMAN COLONIC SMOOTH MUSCLE: ROLE OF ESTROGENS 25 biomedica Digestive, Kidney and Urological Systems , RF Non invasive brain stimulation: a new therapeutic window in neurorehabilitation 25 biomedica Brain Disorders and , RF Prostate and breast cancer progression: biochemical studies for future clinical application of cholesterol modulators 25,17 biomedica Oncology 1 Basic , GR PROGNOSTIC REGISTRY OF CT CORONARY ANGIOGRAPHY IN SUSPECTED CORONARY ARTERY DISEASE RECORD 25,25 clinico assistenziale Cardiovascular and , GR RETRACT: REducing TRAnsition to psychosis by Omega 3 fatty acids ComplemenTation 25,25 clinico assistenziale Biobehavioral and Behavioral Processes , RF Integrated analytical platform for evaluating the effects of exposure to 1950 MHz UMTS signal by means of proteomics and metabolomics studies 25,25 biomedica Biological Chemistry and Macromolecular Biophysics , GR Vascular and inflammatory markers as new predictors of Silent Coronary Artery Disease in Postmenopausal Women 25,25 clinico assistenziale Cardiovascular and , GR A bioinformatic platform for the Systems Biology oriented analysis of variations in tumor genomes. 25,25 biomedica Genes, Genomes and , GR ROLE OF ORAI 1 AND STIM 1 UNDERLYING STORE OPERATED Ca2+ CURRENTS (SOCs) IN STROKE PATHOGENESIS 25,5 biomedica Molecular, Cellular, and Developmental Neuroscience ,00 Pagina 217 di 244

218 2467 GR GUILLAIN BARRÉ SYNDROME AND ITS VARIANTS: INVESTIGATION ON BIOMARKERS FOR PATHOGENESIS AND CLINICAL PRACTICE 25,5 biomedica Brain Disorders and , GR Non coding elements that regulate MeCP2 expression 25,5 biomedica Genes, Genomes and , RF Study on contamination patterns and source identification of foodborne zoonoses and toxic organic compounds and implementation of a surveillance network for reducing the exposure of resident population in Molise region 25,5 biomedica Veterinary Food Safety FOSA 2470 GR EXOSOMES AND TUMOR RELATED VIRUSES. 25,5 biomedica Oncology 1 Basic , GR Understanding the role of TRIM8, a novel p53 target gene, in the physiopatology of gliomas 25,5 biomedica Oncology 1 Basic , RF PREDICTION OF POSTOPERATIVE RESPIRATORY FUNCTION WITH VOLUMETRIC AND DENSITOMETRIC COMPUTED TOMOGRAPHY AND VIBRATION RESPONSE IMAGING IN PATIENTS SUBMITTED TO LOBECTOMY FOR LUNG CANCER 25,5 clinico assistenziale Cardiovascular and , RF OPTIMAL HUMAN OVARIAN TISSUE CRYOPRESERVATION: SLOW FREEZING VERSUS VITRIFICATION 25,5 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Use of Coagulation Factors Concentrate for prevention of clinically significant postoperative bleeding in cardiac surgery 25,5 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , GR Early diagnosis of Mild Cognitive Impairment: a new approach involving genetics, epigenetics and neuroimaging. 25,5 biomedica Genes, Genomes and , GR Multi level factors subserving healthy decision making as a reference for the understanding of decisional impairments in healthy aging, pathological gambling, addiction and Parkinson s disease. An integrated cognitive, personality, neurological and geneti 25,5 biomedica Biobehavioral and Behavioral Processes ,00 Pagina 218 di 244

219 2477 RF Effect of cholera toxin B subunit on the cross talk between intestinal epithelial cells and dendritic cells 25,5 biomedica Immunology , RF INNOVATIVE MODEL TO MEET THE SOCIOCULTURAL NEEDS OF ADULT FOREIGN LANGUAGE SPEAKING CANCER PATIENTS IN THEIR DIAGNOSTIC AND THERAPEUTIC PROCEDURES 25,5 clinico assistenziale Healthcare Delivery and Methodologies , RF Cell therapy in veterinary medicine: identification of specific markers for animal Multipotent Stromal Cell (MSC) technologies 25,5 biomedica Veterinary Animal Health ANHE , GR TERAHERTZ SPECTROSCOPY AND IMAGING FOR DIAGNOSTIC PURPOSES IN REHABILITATION 25,67 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering 2481 RF Oxidative Stress in the pathogenesis of neurodegenerative diseases: glutathione as a new key regulator of neurodegeneration in Friedreich's Ataxia 25,67 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Identification of cancer stem cells in head and neck squamous cell carcinoma: a new model of cancerogenesis 25,67 biomedica Oncology 1 Basic 2483 GR Self Configuring Communication Device for Stable and Reliable Tele Medicine Applications 25,75 biomedica Healthcare Delivery and Methodologies , GR Longitudinal cognitive assessment and communication in amyotrophic lateral sclerosis: eye tracking technology and the use of augmentative and alternative communication strategies 25,75 clinico assistenziale Brain Disorders and , GR Proposal for a Research Project on the assessment of the mechanical properties of the skin tumors. A three years project merging the researchers and technologies between IEO European Institute of Oncology and POLIMI. 25,75 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , RF DNA damage and epigenetic mechanisms in chronic hepatitis C and hepatocellular carcinoma patients 25,84 biomedica Oncology 1 Basic , RF Na+ Ca2+ exchanger as new therapeutical target in management of bacteriainduced heart hypertrophy and related complications 26 biomedica Cardiovascular and ,00 Pagina 219 di 244

220 2488 GR New protein misfolding specificities in Alzheimer's disease and innovative recombinant antibody based approaches for diagnostics, imaging and therapeutics 26 biomedica Molecular, Cellular, and Developmental Neuroscience , RF The assessment of cancer risk behaviours of immigrant populations in Italy and the impact on the welcome context. Strategies for a conscious prevention. 26 clinico assistenziale Risk, Prevention and Health Behavior , GR Tumor cell death and new emerging drugs in sarcomas 26 biomedica Oncology 1 Basic , GR Rare Disease Infant botulism: improvement of diagnostic method, microbiology of agents, clinical management and treatment 26 biomedica Infectious Diseases and Microbiology , GR Maintaining and Retraining Brain Organization Following Limb Immobilization 26 clinico assistenziale Integrative, Functional, and Cognitive Neuroscience , GR NEUROIMAGING AND NEUROPSYCHOLOGICAL ENDOPHENOTYPES OF EATING DISORDERS: GENETIC AND ENVIRONMENTAL RISK FACTORS 26 clinico assistenziale Brain Disorders and , RF ZINC THERAPY: SAFETY AND EFFICACY IN ALZHEIMER S DISEASE PATIENTS 26 clinico assistenziale Brain Disorders and 2495 RF CHARACTERIZATION OF LEUKEMIC STEM CELLS IN PEDIATRIC ACUTE LYMPHOBLASTIC LEUKEMIA 26 biomedica Oncology 1 Basic 2496 GR ANALYSIS OF ONCOGENETIC MECHANISMS OF HEREDITARY LEIOMYOMATOSIS AND RENAL CELL CANCER (HLRCC) 26 clinico assistenziale Genes, Genomes and 0, GR Production of secretory granules with repeating substructure: a suitable mechanism for intracytoplasmic storage of peptides with relevant biological activities 26 biomedica Biological Chemistry and Macromolecular Biophysics , RF POST HARVEST PRODUCTION TREATMENTS FOR THE CONTROL OF VIRAL CONTAMINATION IN BIVALVE MOLLUSKS: TOOLS FOR IMPROVEMENT OF SHELLFISH SAFETY 26 biomedica Veterinary Food Safety FOSA , GR Parathyroid Hormone and Endothelial Progenitor cells in Renal patients: Mobilization and Biological Characterization 26 clinico assistenziale Cardiovascular and ,00 Pagina 220 di 244

221 2500 GR Identification of novel mechanicistic and diagnostic markers of human heart failure: focus on oxidatively modified proteins 26 biomedica Cardiovascular and , RF DEVELOPMENT OF MATCHED PROTOCOL TO ISOLATE, EXPAND AND MAXIMAZE CELL YIELD OF HUMAN ADIPOSE TISSUE DERIVED MSCs TO MEET NEEDS OF CELL THERAPY 26 biomedica Bioengineering Sciences and Technologies , RF OBESITY AND DIABETES/HYPERTENSION RISK IN CHILDREN: PREVENTION AND TREATMENT THROUGH MONITORED PHYSICAL ACTIVITY PROGRAMS 26 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Juvenile justice: development of a monitoring system to evaluate alcohol misuse in arrested teenagers 26 clinico assistenziale Risk, Prevention and Health Behavior , RF EVALUATION OF THE ESTROGENIC PROFILE OF DESMO TUMORS AND ITS CORRELATION TO TUMORAL AGGRESSIVENESS AND ANTI ESTROGENIC THERAPY 26 biomedica Oncology 2 Clinical , RF Malignant gliomas: tumor stem cells and phenotype and cell resistance. MDR and MGMT systems. 26 biomedica Oncology 1 Basic , RF A new treatment of depression in the elderly: positive memory neurostimulation as an alternative to antidepressants? 26 clinico assistenziale Brain Disorders and , GR ENTIFICATION OF NOVEL MOLECULAR TARGETS AND BIOLOGICAL AGENTS FOR THE CHEMOTHERAPY OF MALIGNANT PLEURAL MESOTHELIOMA 26 biomedica Oncology 2 Clinical , RF Elucidation of the Mechanisms Responsible for the Enigmatic in vivo Iduronate 2 Sulfatase (S) Mutant Transcript Correction to Wild Type in Hunter Syndrome 26 biomedica Genes, Genomes and , RF Comprehensive Gene Expression Analysis of Airway Epithelial Cells on All Stages of Chronic Obstructive Pulmonary Disease. 26,17 biomedica Cardiovascular and , RF Reverse translating oncologic cachexia features into innovative therapeutic approaches for lung, liver and pancreatic cancer 26,25 biomedica Oncology 2 Clinical ,00 Pagina 221 di 244

222 2511 GR ENTIFICATION OF MARKERS OF GENETIC INSTABILITY LEADING TO RESISTANCE TO TYROSINE KINASE INHIBITOR THERAPY AND DISEASE PROGRESSION IN CHRONIC MYELO LEUKEMIA 26,25 biomedica Oncology 2 Clinical , RF Randomized controlled trial on the effects of exercise training on bone mineral density and bone fractures risk in elderly patients with heart failure 26,34 clinico assistenziale Biology of Development and Aging , RF Standardization and validation of biomolecular methods for the detection of HAV, HEV and NoV in bivalve molluscs; evaluation of their presence in Italian seas, through coordination of the authorized laboratories at national level. 26,34 biomedica Veterinary Food Safety FOSA 2514 GR Anthracycline induced cardiotoxicity: a molecular and functional approach. 26,5 biomedica Cardiovascular and , GR DIFFERENTIATION OF CANCER CELLS INDUCED BY EXTREMELY LOW FREQUENCY MAGNETIC FIELDS 26,5 biomedica Oncology 1 Basic , RF Safety patient and risk management in a Geriatric Rehabilitation Department 26,5 clinico assistenziale Risk, Prevention and Health Behavior , GR Redox state of tumor microenvironment: effect on cancer cell anchorage, anoikis and acquisition of metastatic phenotype. 26,5 biomedica Oncology 1 Basic , RF Clinical implication of amyloid beta (A beta) and its receptor, the RAGE (Receptor for Advanced Glycation End Product), in the pathogenesis of glaucomatous neurodegeneration and its involvement in cognitive impairment 26,5 biomedica Brain Disorders and , RF POST SURGICAL ADJUVANT THERAPY FOR STAGE III MELANOMA PATIENTS 26,5 clinico assistenziale Oncology 2 Clinical , RF Safety of workers with implanted medical devices in MRI environment: criteria for occupational risk evaluation 26,5 biomedica Healthcare Delivery and Methodologies , RF COGNITIVE STIMULATION PROGRAM TO ANTAGONISE COGNITIVE DECLINE, TO IMPROVE BEHAVIORAL DISTURBANCES AND QUALITY OF LIFE, IN PRODROMAL AND MILD TO MODERATE STAGES OF ALZHEIMER'S DISEASE. 26,5 clinico assistenziale Brain Disorders and Pagina 222 di 244

223 2522 GR Innate immune response to respiratory virus infection in asthmatic children 26,5 biomedica Immunology , RF Abnormal ALT levels are a surrogate marker of acute Cytomegalovirus (CMV) infection that could reduce the risk of CMV transfusion transmitted infection? 26,5 clinico assistenziale Infectious Diseases and Microbiology , GR Autophagy manipulation as a strategy for fighting neuropathic pain and facilitating regenerative processes 26,5 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Prospect study on the social care integrated management of the oncological subject, in patients older than 70, with the aim of elaborating a new organizational model for the integration between hospital and extra hospital assistance 26,5 clinico assistenziale Risk, Prevention and Health Behavior , RF Exposure to dioxin: cellular damages and biological implications. Effects on viral infection, differentiation processes and cell proliferation 26,5 biomedica Veterinary Animal Health ANHE , GR The manometric pattern can be the key for the treatment of esophageal achalasia 26,5 clinico assistenziale Digestive, Kidney and Urological Systems , RF Surveillance of the circulation of rotaviruses in the infantile population of Sicily and of the ecology of rotavirus infections in view of the introduction of a rotavirus vaccine. Implications for vaccine adoption and immunization policies. 26,5 biomedica Population Sciences and Epidemiology , RF A Novel Therapeutic Strategy Targeting Photoreceptor Oxidative Damage in ABCR related Retinal Degenerations: An Experimental and Clinical Study. 26,5 biomedica Brain Disorders and , RF Traffic related air pollution near main roads and risk of respiratory tract cancers in the North East of Italy 26,67 biomedica Population Sciences and Epidemiology , RF Survival of Lactic Acid Bacteria (LAB) able to produce biogenic amine (BA) in the human gastrointestinal tract 26,67 biomedica Veterinary Food Safety FOSA , GR Sleep Wake cycle and outcome of the Vegetative Patients and Minimal Responders 26,75 clinico assistenziale Brain Disorders and , GR Evaluation and validation of new bladder cancer markers through a new phosphoproteomic approach 26,75 clinico assistenziale Oncology 2 Clinical ,00 Pagina 223 di 244

224 2534 GR CAROT ATHEROSCLEROSIS: MARKERS OF PROGRESSION AND INFLUENCE ON COGNITIVE IMPAIRMENT OCCURRENCE 26,75 biomedica Brain Disorders and , RF Clinical trial for the assessment of the safety and efficacy of autologous mesenchymal stem cell transplantation in parkinsonism 26,75 biomedica Brain Disorders and , RF Comparative evaluation of the diagnostic and prognostic role of serum and urinary PCA3, of advanced imaging techniques and of tissue and circulating molecular markers in prostate cancer patients. 26,75 clinico assistenziale Oncology 2 Clinical , GR Biological dosimetry of Magnetic Resonance procedures in patients and occupational workers 26,84 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Reproductive and hormonal gonadal function assessment in type 1 and type 2 diabetic patients 26,84 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Functional Analysis of Homeobox Genes and micrornas Expression Profiles in Mesenchymal Stem Cells. Application to Bone Tissue Engineering. 27 biomedica Biology of Development and Aging , GR Robotic and Mental Practice training effects: functional brain reorganization in walking recovery 27 clinico assistenziale Brain Disorders and , RF SETUP AND APPLICATION OF INNOVATING MODELS BASED ON BIOTECHNOLOGICAL METHODS FOR THE CONTROL AND MANAGEMENT OF VIRUS, PARASITE AND MICROCONTAMINANT FOOD RISKS 27 biomedica Veterinary Food Safety FOSA , GR Specific absorption of putative pathogenetic anti domain I of beta2 glyoprotein I (admi/beta2gpi) antibodies in high risk patients with Antiphosphiolipid Syndrome (APS) 27 biomedica Vascular and Hematology , RF Management of manpower health and productivity in an Infectious Dieseases Dept 27 clinico assistenziale Risk, Prevention and Health Behavior RF Novel diagnostic and treatment strategies for sepsis in critically ill patients 27 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , ,00 Pagina 224 di 244

225 2545 GR HISTOLOGICAL DATA FROM ATRIAL BIOPSY COUPLED TO TRANSSEPTAL PUNCTURE IN ATRIAL FIBRILLATION PATIENTS 27 clinico assistenziale Cardiovascular and , GR COCAINE ADDICTION AND CARDIOVASCULAR DAMAGE: an in vivo model combined with an in vitro model to evaluate the possible role of oxidative stress in accelerated atherosclerosis and left ventricular hypertrophy. 27 clinico assistenziale Risk, Prevention and Health Behavior , GR Involvement of the atypical cytokine and chemokine receptors Tir8 and D6 in the pathogenesis of Inflammatory Bowel Disease 27 biomedica Immunology , GR Studies of the pathogenic mechanisms of Porcine Circovirus type 2 (PCV2) and Torque Teno virus (TTV) that can be transmitted from animals to human 27 biomedica Veterinary Animal Health ANHE , GR SENTINEL NODE ENTIFICATION WITH SENTINELLA INTRAOPERATIVE GAMMACAMERA vs TRADITIONAL GAMMAPROBE: IS THERE AN IMPROVEMENT IN ACCURACY? 27 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , GR Evaluation of the frequency of putative cancer stem cells in paired primary and metastastic tissue in breast cancer patients. 27 biomedica Oncology 1 Basic , RF DIETARY USE OF GOAT MILK AND DAIRY PRODUCTS IN THE PREVENTION OF SKELETAL SYSTEM DEGENERATIVE DISEASES, WITH PARTICULAR REGARD TO PATIENTS IN NEUROREHABILITATION: NUTRITIONAL AND HYGIENIC ASSESSMENT. 27 biomedica Veterinary Food Safety FOSA , RF Venous Thromboembolism (VTE) risk in patients with cancer undergoing surgery and anesthesia 27 clinico assistenziale Vascular and Hematology , GR Clinical, pharmacological and biochemical correlation between epilepsy and depression. Identification of common therapeutical approaches. 27 biomedica Brain Disorders and , RF WHOLE GENOME GENE EXPRESSION PROFILING OF CIRCULATING TUMOR CELLS (CTCs), METASTATIC AXILLARY NODES AND PRIMARY TUMORS BY SINGLE CELL INTERROGATION METHODOLOGY IN PATIENTS WITH LOCALLY ADVANCED BREAST CANCER 27 biomedica Oncology 2 Clinical ,00 Pagina 225 di 244

226 2555 GR Introducing translational clinical endpoints in longevity studies of laboratory mice: development of mice models of frailty or robustness from metallothionein transgenic mice 27 biomedica Biology of Development and Aging , GR In vitro studies on the effects of CFTR mutations on RNA expression and protein function 27 biomedica Genes, Genomes and , GR Molecular characterization and role of RCAN3 (Regulator of calcineurin family member 3) in cardiac development and function 27 biomedica Cardiovascular and , GR Beta catenin mutation in desmoid tumor: impact on prognosis and response to commonly used drugs 27 clinico assistenziale Oncology 2 Clinical , RF Analysis of biological processes during wound healing: clinical and forensic applications 27 biomedica Cell Biology , RF Predictivity for MPN of screening for JAK2 V617F ad TET2 mutations in asymptomatic patients with splanchnic thrombosis and usefulness in clinical management and counselling. 27 clinico assistenziale Vascular and Hematology , RF Searching into possible molecular and genetic relationships among the metabolic syndrome, cardiovascular disease and longevity: novel proposed markers of aging and premature atherosclerosis. 27,17 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Systematic active research and epidemiological analysis of occupational cancer cases 27,25 biomedica Population Sciences and Epidemiology 2563 RF ROLE OF ANASTHESIA ON IMMUNE RESPONSE 27,25 clinico assistenziale Immunology , RF MULTISCIPLINARY CARE CENTER FOR PREGNANT AND POST PARTUM WOMEN 27,25 clinico assistenziale Risk, Prevention and Health Behavior , RF Investigating early cognition by electrophysiology and genomics: a study of infant twins 27,25 biomedica Biobehavioral and Behavioral Processes , GR Unawareness of Disease, Functional Recovery, Treatment Compliance and Rehabilitation Outcome: a Multidimensional Approach 27,5 clinico assistenziale Brain Disorders and ,00 Pagina 226 di 244

227 2567 GR A possible use of membrane vesicles in medicine 27,5 biomedica Cell Biology , RF Human whole genome expression profiles in tissues and in the peripheral blood mononuclear cell (PBMC) of patients with ruptured and unruptured aneurysms for the identification of novel predictive genetic biomarkers. 27,5 biomedica Genes, Genomes and , RF MicroRNAs expression profile and modulation in non small cell lung cancer progression. 27,5 biomedica Oncology 2 Clinical , GR Anticancer treatment induced cardiovascular diseases involve alterations in resident cardiac and circulating progenitor cells and is gender dependent: new targets for the prevention and therapy of cardiotoxicity. 27,5 biomedica Oncology 2 Clinical , RF RESTRICTIVE TRANSFUSION POLICY IN CARDIAC SURGERY: FINDING THE CLINICALLY ACCEPTABLE LIMIT OF POSTOPERATIVE ANEMIA 27,5 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Reduction of amyloid beta load in Alzheimer s disease by Toll like Receptor activity modulation with low and high molecular weight Hyaluronan : in vitro and in vivo studies for a new therapeutic approach to the disease. 27,5 biomedica Molecular, Cellular, and Developmental Neuroscience , GR Use of magnetic resonance venography as a validation tool of the relationship between chronic cerebrospinal venous insufficency and multiple sclerosis 27,5 clinico assistenziale Integrative, Functional, and Cognitive Neuroscience , GR BIOMOLECULAR CHARACTERIZATION OF MELANOMA ARISED FROM PRE EXISTENT NEVUS ENTIFIED USING DERMOSCOPIC APPROACH 27,5 biomedica Oncology 2 Clinical , GR Incidental Thyroid Nodules in Melanoma patients: evaluation of their malignancy and correlated hormonal abnormalities. Detection of RET tyrosine kinase receptor (RET/PTC) rearrangements and BRAF mutation in thyroid cells in patients with concomitant me 27,5 clinico assistenziale Oncology 1 Basic , RF Altered Vessel Signaling And Impaired Recruitment of Endothelial Progenitor Cells as a Mechanisms Underlying the Chronic Ischemic Complications of Diabetes. 27,5 biomedica Vascular and Hematology , GR Physical rehabilitation in a neurological unit: Burnout and coping strategies 27,5 clinico assistenziale Risk, Prevention and Health Behavior ,00 Pagina 227 di 244

228 2578 RF Mirror therapy rehabilitation after child brain tumor hemiparesis 27,5 clinico assistenziale Brain Disorders and , GR The HIV 1 pathogenicity factor Nef as a novel therapeutic target in opportunistic infections. 27,75 biomedica AS and Related Research , RF Extravasation project: prevention, treatment and monitoring 27,75 clinico assistenziale Oncology 2 Clinical GR Endocrinological and metabolical effects of bariatric surgery 28 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences RF Bladder wall investigation in patients affected by bladder outlet obstruction 28 clinico assistenziale Digestive, Kidney and Urological Systems GR Optimization of the use of Topotecan as anti hypoxia drug 28 biomedica Oncology 2 Clinical , , , , GR NT UF study: NT probnp driven volume unloading in decompensated heart failure: ultrafiltration versus intravenous diuretics. Neurohormonal effects and prognosis. 28 clinico assistenziale Cardiovascular and , GR Investigation of Immune Function in Individuals with Different Status of Alpha 1 Antitrypsin Deficiency 28 biomedica Cardiovascular and , GR Notch1 and N cadherin expression as possible novel prognostic markers in cutaneous melanoma 28 biomedica Oncology 1 Basic , GR In vivo evaluation of the effects caused by plant extracts and their components on the proliferation and differentiation of adult stem cells in a simple animal model for potential applications in the field of regenerative medicine 28 biomedica Cell Biology , GR Internal Loop Recorder Device to detect atrial fibrillation in patients with cryptogenic ischemic stroke: a randomised controlled trial 28 clinico assistenziale Cardiovascular and ,00 Pagina 228 di 244

229 2589 GR SUBCLINICAL MYOPATHY IN COLORECTAL CANCER AT THE CLINICAL ONSET OF THE DISEASE: DIAGNOSTIC AND PROGNOSTIC ROLE OF HUMORAL BIOMARKERS OF MUSCLE DAMAGE AND REGENERATION 28 biomedica Oncology 1 Basic , GR OXATIVE STRESS MEDIATED NEURONAL DAMAGE IN NEURODEGENERATIVE DISORDERS: NEW POTENTIAL THERAPEUTIC APPROACHES FOR FRIEDREICH S ATAXIA 28 biomedica Brain Disorders and , RF Pressure ulcers and microbial biofilms: development of novel drug releasing dressings for their prevention and treatment 28 biomedica Infectious Diseases and Microbiology 2592 GR Characterization of prostate cancer stem cells for the identification of new prognostic markers and/or targets for novel anticancer therapies. 28 biomedica Oncology 2 Clinical , GR Plasmatic oxidative stress markers in Sicilian people living in industrial areas 28 biomedica Risk, Prevention and Health Behavior , GR New therapeutic perspectives in the treatment of infantile hemangiomas in rapid proliferative phase: use of propranolol and evaluation of molecular markers involved in its mechanism of action. 28 biomedica Vascular and Hematology , GR Parents adolescents relationships: the key of successful prevention in adolescence 28 clinico assistenziale Risk, Prevention and Health Behavior GR Mucosal cytokine levels in colorectal cancer 28 clinico assistenziale Oncology 2 Clinical , , GR TOURETTE SYNDROME IN CHILDHOOD AND ASOLESCENCE: VALATION AND CLINICAL PHARMACOLOGICAL APPLICATION OF A QUALITY OF LIFE SCALE 28 clinico assistenziale Biobehavioral and Behavioral Processes , GR Pathways controlling ErbB2 mediated cardiac protection: mitochondrial function and calcium cycling during oxidative stress. 28 biomedica Cardiovascular and , RF Traditional and organic foods comparison in patients with different degrees of obesity versus healthy subjects: analysis of foods and their chemical/physical evaluation. 28 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences ,00 Pagina 229 di 244

230 2600 RF A novel class of molecules against Gram negative bacteria 28 biomedica Infectious Diseases and Microbiology , RF A novel therapeutic strategy against breast cancer: camp elevating drugs and leptin 28 biomedica Oncology 1 Basic , RF Early diagnosis and K Ras, PT53, APC and BRAF mutations in colorectal cancer 28,25 biomedica Genes, Genomes and , GR CAlabRian Epidemiological observatory on early stages of Kney dysfunction and cardiovascular risk factors at pediatric age The CAREK CV project 28,25 clinico assistenziale Population Sciences and Epidemiology 2604 GR MESENCHYMAL STEM CELL TRANSPLANTATION IN NEUROPATHIC PAIN TREATMENT 28,25 biomedica Molecular, Cellular, and Developmental Neuroscience , RF On the road to growth Empowering mental health in adolescents, with particular focus on preventing or reducing drug use 28,25 clinico assistenziale Risk, Prevention and Health Behavior , RF In vivo, non invasive, quantification of ß cell mass loss during diabetes progression by means of Diffusion Weighted Magnetic Resonance Imaging (DWI MRI) and Manganese Enhanced MRI (ME MRI), performed on mouse model diabetes type 2 and human Impaired Gluc 28,34 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF A study investigating the presence of prion infectivity in Sardinian ovine cheese 28,34 biomedica Veterinary Food Safety FOSA , GR Effects of pharmacological and natural compounds on putative biomarkers of prostate related diseases: integration of novel endpoints derived by system biology approaches. (ANDROS) 28,34 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences 2609 GR DEVELOPMENT OF EVENCE BASED GUELINES TO TREAT CARPAL TUNNEL SYNDROME AND ULNAR NERVE AT ELBOW 28,5 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , GR GENetically determined Endothelial Dysfunction and Insulin Resistance (GENEDIR): an experimental and translational study on the molecular mechanisms linking endothelial dysfunction, insulin signalling and cardiovascular damage 28,5 biomedica Cardiovascular and ,00 Pagina 230 di 244

231 2611 GR New methodologies for monitoring of Vibrio spp. in crustaceans and for evaluation of their potential pathogenicity 28,5 biomedica Infectious Diseases and Microbiology , GR Microenvironment modifications in cancer induced by chronic stress 28,5 biomedica Biobehavioral and Behavioral Processes 0, GR Co occurrence of asymptomatic brain lesions, inter atrial septal abnormalities and cerebrovascular risk factors in the young population of Verona. 28,75 clinico assistenziale Brain Disorders and 2614 GR AN INNOVATIVE TRANSDERMAL DRUG DELIVERY DEVICE FOR THE TREATMENT OF TYPE 1 DIABETES 29 biomedica Bioengineering Sciences and Technologies , GR Optimizing of DNA vaccination with synapsin in the suppression of experimental autoimmune encephalomyelitis 29 biomedica Immunology , GR Post mortem adult neural stem cell transplantation on traumatic spinal cord injury and neurodegenerative diseases 29 biomedica Molecular, Cellular, and Developmental Neuroscience , RF Exercise cardiac Output Change in Ventricular Reconstruction for heart failure due to Ischemic Cardiomyopathy 29 clinico assistenziale Cardiovascular and , RF Prospective study on movement perception and performance in early autism: clinical predictors and neural correlates 29 clinico assistenziale Brain Disorders and , RF Tandem treatment with 90Y and 177Lu labelled somatostatin analogues of patients with neuroendocrine tumours non responding to conventional therapy 29 clinico assistenziale Oncology 2 Clinical , GR Aminoacid substitutions (AAS) rate of proteins encoded by mitochondrial DNA (mtdna) in high grade glioma patients: a translational approach. 29 clinico assistenziale Emerging Technologies and Training in Neurosciences 2621 GR The Emilia Romagna First Episode Psychosis project: a contribution to the European Network of National Schizophrenia Networks Studying Gene Environment Interactions 29 biomedica Biobehavioral and Behavioral Processes , RF Comparative analysis of vitreal inflammatory and angiogenic factors in vitreoretinal disorders 29 biomedica Cell Biology Pagina 231 di 244

232 2623 GR NON DESTRUCTIVE 3D ANALYSIS OF BONE IMPLANT INTERFACE WITH HIGH RESOLUTION MICRO CT SYSTEM: DEVELOPMENT OF 3D PARAMETERS FOR OSTEOINTEGRATION EVALUATION AND THEIR VALATION BY MEAN OF 2D HISTOMORPHOMETRY AND MECHANICAL TESTS 29 biomedica Musculoskeletal, Oral and Skin Sciences , RF SCAFFOLD INTERACTION WITH BONE MARROW DERIVED MESENCHYMAL STEM CELLS IN AN ONE STEP PROCEDURE FOR OSTEOCHONDRAL REPAIR 29 biomedica Musculoskeletal, Oral and Skin Sciences , RF Definition of new long term predictive biomarkers of TD2 and associated CVD, and identification of novel therapeutic targets. 29 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Genetic and biochemical markers for Huntington's disease. 29 biomedica Brain Disorders and , GR Multi layer analysis of adult human stromal cells from different origins: insights into cardiovascular differentiation 29 biomedica Cardiovascular and , RF Development of algorithms for real time detection of neonatal seizures by analyzing video signals 29 biomedica Brain Disorders and , RF Beyond Adoption and Diffusion towards "Normalization". Integrating new technologies within health organizations and systems: a study of factors that promote or inhibit routine embedding of innovations using the Normalization Process Theory (AD NORMAL) 29 clinico assistenziale Healthcare Delivery and Methodologies , RF COMPLEMENTARY THERAPIES IN PARKINSON S DISEASE: A MULTIMENSIONAL APPROACH FOR A BETTER QUALITY OF LIFE. 29,17 clinico assistenziale Integrative, Functional, and Cognitive Neuroscience , GR Role of insulin in early pericyte loss: implications in the pathogenesis of diabetic retinopathy. 29,25 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF MUTATIONAL ANALISYS OF GENES PKD1 E PKD2 IN SICILIAN POPULATION WITH POLICISTIC KNEY DISEASE 29,34 biomedica Genes, Genomes and ,00 Pagina 232 di 244

233 2633 RF INNOVATIVE INTEGRATE CLINICAL PATHWAY TO IMPROVE THE OUTCOME OF PATIENTS AFFECTED WITH PANCREATIC CANCER 29,34 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , RF An integrated approach to the optimization of dose and image quality for computed radiography and digital radiography 29,34 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Long term assessment of the immunological profile in patients with psoriasis/psoriatic arthritis treated with biologics targeting immune response mediators 29,5 clinico assistenziale Immunology , RF Clinical and psychological advantages of controlling pain in high risk surgical patients: Neurophysiological monitoring of the afferent and efferent pain pathway. 29,5 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , GR After traumatic brain injury: Evaluation of the procedures helping patients to return to drive and testing of a new rehabilitation protocol. 29,5 biomedica Risk, Prevention and Health Behavior 2638 GR VIRAL MONITORING FOR PREVENTION OF SEVERE POST TRANSPLANT INFECTIONS AND VIRUS LINKED CANCER 29,5 clinico assistenziale Immunology , RF SPONTANEOUS MAST CELL TUMOURS IN DOG AS A MODEL FOR HUMAN TUMOURS EXPRESSING C KIT RECEPTOR: DEVELOPING A BIOBANK FOR TRANSLATIONAL ANGIOGENETIC STUDIES AND TARGETED THERAPYES 29,5 biomedica Oncology 1 Basic , RF Autistic phenotype: a clue for the diagnosis of the idic(15) syndrome; a neurogenetic disorder characterized by autistic symptoms, intellectual disability, and epilepsy. Study of the neuro behavioral phentoptype, and molecular cytogenetics, with genotype 29,5 clinico assistenziale Brain Disorders and , GR Role of functional CD4+T cells subsets in the collateral response to acute ischemia 29,5 biomedica Immunology , RF IFN alpha improves Vgamma9Vdelta2 T cell antiviral activity : implication for new combined therapeutic strategies in HCV infection 29,5 biomedica Immunology , RF Management of aggression in dogs: ethologic and laboratory parameters 29,5 biomedica Veterinary Animal welfare ANWE ,00 Pagina 233 di 244

234 GR Innovative tools for biological agents exposure assessment in workplaces 29,75 biomedica Infectious Diseases and Microbiology RF Evaluation of stalking phenomenon: victims, stalkers and professional 29,75 clinico assistenziale Risk, Prevention and Health Behavior , , GR NON ALCOHOLIC FATTY LIVER DISEASE (NAFLD), GENETIC POLYMORPHISMS, HORMONAL PROFILE AND LIPOMICS AS NEW RISK FACTORS FOR ATHEROSCLEROSIS: A STUDY IN THREE DIFFERENT VASCULAR DISTRICTS. 30 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences 0, GR Emerging viral infections: diagnosis, pathogenesis and host immune response 30 biomedica Infectious Diseases and Microbiology , GR Potential interplay of cancer stem cells and NF kb inflammatory pathway in gastrointestinal adenocarcinoma: novel cancer approaches 30 biomedica Oncology 1 Basic , GR A population based characterization of potential microbial etiologies of Crohn disease and Type 1 Diabetes Mellitus 30 biomedica Infectious Diseases and Microbiology 2650 GR ESTROGEN RECEPTOR BETA EXPRESSION AND METHYLATION OF GENE ER AS A MOLECULAR PROGNOSTIC MARKER OF CANCER PROGRESSION IN ULCERATIVE COLITIS 30 biomedica Digestive, Kidney and Urological Systems , RF Late onset epilepsy: epidemiology, pathogenesis and predictive criteria of recurrence after a first unprovoked seizure 30 clinico assistenziale Molecular, Cellular, and Developmental Neuroscience , RF GENESIS, TRANSMISSION AND PROCESSING OF NEURAL INFORMATION IN NEURODEGENERATIVE DISEASES 30 clinico assistenziale Brain Disorders and , RF Molecular analysis of pathways involving p53 family members and non clustered homeobox genes in mammary gland 30 biomedica Oncology 1 Basic 2654 GR Isolated ruminant mammary stem cell population and uses thereof for production of transgenic proteins in vivo 30 biomedica Biology of Development and Aging , GR Role of Notch 4 in rigeneration and neoangiogenesis of hepatocellular carcinoma. 30 biomedica Oncology 1 Basic ,00 Pagina 234 di 244

235 2656 GR ANALISYS OF SHORT TERM MORTALITY BASED ON REGISTRY FOR TYPE 1 DIABETES IN ITALY (RI) 30 clinico assistenziale Population Sciences and Epidemiology , GR Direct assessment of ventricular arterial coupling in asymptomatic patients at risk of developing heart failure. Role of gender and age. 30 clinico assistenziale Cardiovascular and , RF Dysregulation of Expression and Functionality of small non coding RNAs (mirnas) in Breast Cancer and Intervention by Curcumin 30 biomedica Risk, Prevention and Health Behavior , RF Development and clinical applications of natural foods with antiinflammatory properties 30 biomedica Cardiovascular and , RF IN VITRO AND IN VIVO ENTIFICATION OF NOVEL MORPHO BIOCHEMICAL MARKERS OF LIVER FIBROSIS AND THEIR TRANSLATION INTO CLINICAL PRACTICE 30 biomedica Digestive, Kidney and Urological Systems 2661 GR New approach for in vitro study of fixture abutment connections to avoid implant failure 30,17 biomedica Bioengineering Sciences and Technologies , GR Three dimensional dosimetry for radiotherapy by means of optically detected Fricke gel 30,25 biomedica Oncology 2 Clinical 2663 RF Percutaneous injection of bone substitute in hips of the severe osteoporotic patients to prevent fractures 30,34 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , GR Genetic and molecular physiopathology of Intrahepatic Cholestasis of Pregnancy: possible correlations with the development of fetal complications 30,34 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Development of innovative instruments for the characterization and evaluation of high frequency percussive ventilation systems 30,5 biomedica Bioengineering Sciences and Technologies , GR <<Hybrid>> revascularisation by combined CABG and PCI in multivessel coronary disease. A randomized comparison with conventional coronary by pass surgery 30,5 clinico assistenziale Cardiovascular and ,00 Pagina 235 di 244

236 2667 GR A fmri STUDY ON BRAIN FUNCTIONAL CHANGES AND NEUROPLASTICITY IN INFLAMMATORY DISORDERS 30,5 biomedica Digestive, Kidney and Urological Systems 9.000, RF Effectiveness of Selective Intercostal Neurectomy for Chronic Pain following Breast Surgery 30,5 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Assessment of kinetic of selected priority contaminants in three species of aquacultured bivalves and study of relationships to farming environment project BIVA CONT 30,67 biomedica Veterinary Food Safety FOSA , GR Role of estrogen receptor in the uptake of recombinant MnSOD in tumor cells 30,84 biomedica Oncology 1 Basic , GR A multifunctional approach: from animal welfare through product quality to reach consumer health in poultry meat chains 31 biomedica Veterinary Food Safety FOSA , GR Role of micrornas in human glioblastoma 31 biomedica Oncology 1 Basic , RF A Gene array study of early tight junction alterations in the neoterminal ileum after curative resection in Crohns disease. 31 clinico assistenziale Digestive, Kidney and Urological Systems , RF Monitoring of heavy metals and nanoparticles in fishes and baby foods of animal origin 31 biomedica Veterinary Food Safety FOSA , RF INTEGRATED MODEL OF NOSOCOMIAL MICROBIOLOGIC MONITORING AND EPEMIOLOGICAL SURVEILLANCE. 31 clinico assistenziale Infectious Diseases and Microbiology , GR Re sequencing protocols, an high throughput molecular approach for diagnosis of clinically heterogeneous genetic disorders 31 biomedica Genes, Genomes and , RF Phase 2/3, twelve month, multicenter, intra subject controlled (retrospectiveprospective), open label, active treatment study to evaluate the efficacy, safety, tolerability and pharmacokinetics of cinacalcet hydrochloride for the treatment of secondary h 31 clinico assistenziale Digestive, Kidney and Urological Systems ,00 Pagina 236 di 244

237 2678 GR Molecular modeling of antibiotic efflux systems in Gram negative bacteria: unveiling the relations among energy transfer, proteins dynamics and extrusion of antibiotics 31 biomedica Biological Chemistry and Macromolecular Biophysics , GR Design and synthesis of new molecules active against multidrug resistant bacteria. 31 biomedica Interdisciplinary Molecular Sciences and Training GR INHIBITION OF HDAC6 FUNCTIONS IN NOVEL THERAPEUTIC APPROACHES 31 biomedica Oncology 1 Basic , , GR BIOMARKERS RESEARCH FOR DIFFERENTIAL AND NONINVASIVE DIAGNOSIS OF CHRONIC ALLOGRAFT DYSFUNCTION IN KNEY TRANSPLANTATION 31 clinico assistenziale Digestive, Kidney and Urological Systems , RF PET/CT guidance for adaptive PTV tomotherapy re irradiations in local relapse tumors or in field secondary tumors 31,25 clinico assistenziale Oncology 2 Clinical 2683 RF Project for a global therapeutic strategy of Transcatheter aortic valve implantation (TAVI) for isolated severe aortic stenosis in Veneto 31,25 clinico assistenziale Cardiovascular and , GR ACE I and ACE II expression in normal and UVB induced damage conjunctiva cells and its relationship with the pterygium disease 31,25 biomedica Immunology , RF Inhaled anesthesia, cognitive decline progression and Alzheimer s Disease acceleration in older subjects with Mild Cognitive Impairment 31,5 clinico assistenziale Brain Disorders and , RF An integrated functional and bioinformatic approach to identify deregulated EMTassociated pathways in the progression of epithelial ovarian and thyroid cancer and melanoma 31,67 biomedica Oncology 1 Basic , GR Evaluation of the individual susceptibility through the analysis from "buccal swab" of genetic polymorphisms of phase 1 enzymes (CYPs) and phase 2 (GSTs) in subjects exposed to benzene and ethical aspects, liceity of screening genetic application in wor 31,75 biomedica Genes, Genomes and , GR BIOMARKERS FOR THE EVALUATION OF INFLUENCE OF TOBACCO SMOKING ON THE PROGRESSION OF NEURODEGENERATIVE DISEASES 32 clinico assistenziale Brain Disorders and ,00 Pagina 237 di 244

238 2689 GR Efficacy, Safety and Pharmacokinetics of Rituximab in Refractory Nephrotic Syndrome due to Primary Glomerulonephritis: Correlation with clinical outcomes and laboratory markers. 32 biomedica Digestive, Kidney and Urological Systems 0, GR Stem cell therapy for end stage liver disease due to non alcoholic steatohepatitis 32 biomedica Digestive, Kidney and Urological Systems , GR Neuropsychological assessment and rehabilitation in brain cancer patients: a multidisciplinary approach 32 clinico assistenziale Biobehavioral and Behavioral Processes , GR Different significance among critical factors affecting effectiveness of the most important biological stimulators in regenerative medicine of orthopedics and traumatology. 32 biomedica Musculoskeletal, Oral and Skin Sciences , GR The ability to maintain and retrieve delayed intentions. A study on the neurocognitive and morphological aspects of prospective memory and its modulation in individuals with Parkinson s disease. 32 clinico assistenziale Biobehavioral and Behavioral Processes , GR Comparison between two different types of therapeutic groups for Eating Disorders, a trial to appraise non inferiority and costs of CBT versus 12 step program 32 clinico assistenziale Biobehavioral and Behavioral Processes , RF Medical or Endovascular Treatment for Renal Artery Stenosis (METRAS): a randomized study. 32,17 clinico assistenziale Vascular and Hematology , RF Correlation between environmental pollution and malignant cancer in areas of high risk of exposure in the Puglia Region of Italy. 32,17 clinico assistenziale Population Sciences and Epidemiology , GR Randomized controlled trials on the prevention of alcohol misuse among adolescents through the dissemination of school based and web based Metacognitive Prevention of Alcohol Use programme [M PAU] 32,25 clinico assistenziale Risk, Prevention and Health Behavior , GR STUDY OF THE DIFFERENT GENE EXPRESSION IN PERIFERAL LYMPHOLCYTES AND IN PRIMARY/RECURRENT OVARIAN CANCER NEOPLASTIC TISSUE THROUGH DNA/PROTEIN MICROARRAY AND REAL TIME PCR ANALYSIS. 32,5 biomedica Oncology 1 Basic ,00 Pagina 238 di 244

239 2699 GR Collaborative environment for Clinical Audit by integration of NUI (Natural User Interface), Surface Computing, 3D Dynamical Visualization and Imaging Fusion technique 32,5 biomedica Healthcare Delivery and Methodologies , GR Correlation between imaging and genetic data for early diagnosis of Alzheimer Disease 32,5 clinico assistenziale Brain Disorders and , RF HEALTH, BEHAVIOUR AND SOCIOENVIRONMENTAL FACTORS IN ADULTS WITH INTELLECTUAL DISABILITY 32,5 clinico assistenziale Healthcare Delivery and Methodologies , RF Animal model of pharmacological modification of the blood brain barrier to increase accumulation of anticancer drugs within brain tumor tissue 32,75 biomedica Brain Disorders and , GR Ivabradine for heart rate control in heart transplanted patients: a clinical study. 33 clinico assistenziale Cardiovascular and , GR Differential biomolecular involvement of intracellular pathways during the progression from myocardial hypertrophy to heart failure in the aortic stenosis 33 biomedica Cardiovascular and , GR Hormonal peptides and intestinal mucosal proteins as possible factors predisposing to weight regain after a period of weight loss. 33 biomedica Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Coping Strategy and Quality of life in Patients with moderate to severe stroke 33 clinico assistenziale Risk, Prevention and Health Behavior , GR In vitro and in vivo models to assess calcium homeostasis in Alzheimer's disease and to explore its involvement in the beneficial effects of environmental enrichment. 33 biomedica Emerging Technologies and Training in Neurosciences 2708 RF Randomized Clinical Trial to confront the efficacy of treatment in patients with grade 2 and grade 3 obesity, of low calory diet Vs entheral ketogenic nutrition Vs oral ketogenic nutrition. 33 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , GR Setting up a new method for the determination of nitrites and nitrates in vegetables and baby food 33,25 biomedica Biological Chemistry and Macromolecular Biophysics ,00 Pagina 239 di 244

240 2710 GR Dysfunctions in biogenesis of lysosome pathways in Parkinson Disease 33,5 biomedica Molecular, Cellular, and Developmental Neuroscience , GR How to revert the disease progression from chronic and persistent HCV infection to the hepatocellular carcinoma: a metabolic way 33,5 clinico assistenziale Oncology 1 Basic , RF Cardiovascular risk in sistemic sclerosis 33,67 clinico assistenziale Cardiovascular and GR Epilepsy and Hirsutism 33,75 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences GR Detection of Bacillus anthracis in contaminated soils by immunomagnetic method 34 biomedica Infectious Diseases and Microbiology , , , RF Multiple Myeloma (MM) and Osteo Immunology: role of Notch in the expression of chemokines and cytokines as new predictive markers 34 biomedica Musculoskeletal, Oral and Skin Sciences , GR SENTINEL LYMPH NODE BIOPSY BY INDOCYANINE GREEN FLUORESCENCE IN BREAST CANCER VS RADIOCOLLO MAPPING PROCEDURE 34,5 clinico assistenziale Oncology 2 Clinical , GR Impact of Surgical Treatment of the Hyperparathyroidism on Cardiovascular Risk. Evaluation of Coronary Microvascular Function Before and After Parathyroidectomy Performed with Transthoracic Doppler Echocardiography. 34,5 clinico assistenziale Cardiovascular and , GR Non invasive monitoring of hepatic steatosis in patients with HIV infection undergoing orthotopic liver transplantation: a pilot case control study based on Magnetic Resonance Spectroscopy 34,5 clinico assistenziale AS and Related Research , RF Advanced Molecular BioMedicine of Complex Systems: Molecular Analysis of the MicroRNA Transcriptome in Breast and Colorectal Carcinoma through High Throughput Technology to Identify Diagnostic and Prognostic Biomarkers 34,5 biomedica Genes, Genomes and , RF THE DEVELOPMENT OF A BEST PRACTICE MODEL TO PALLIATIVE CARE: AN EVALUATION RESEARCH IN SICILY 35 clinico assistenziale Healthcare Delivery and Methodologies ,00 Pagina 240 di 244

241 2721 RF Neurobehavioral problems in autistic spectrum disorder patients undergoing pediatric dentistry care: an observational and experimental study aimed at an innovative, tailored approach in special needs patients. 35 clinico assistenziale Biobehavioral and Behavioral Processes , GR Cell initiating human acute myeloid leukemia: dissecting progenitor cell driven trascriptional programs 35 biomedica Oncology 1 Basic , GR Development of a 3D imaging system for breast volume, shape and symmetry assessment in preoperative planning and follow up in breast reconstructive surgery after mastectomy, quadrantectomy and for developmental breast asymmetries 35 clinico assistenziale Bioengineering Sciences and Technologies , GR Genomic microarrays in mental retardation: from research to diagnosis 35 clinico assistenziale Genes, Genomes and RF Prevention of Pressure Ulcers: a different nursing model 35 clinico assistenziale Healthcare Delivery and Methodologies 0, , GR Colorectal surgery in very old people. Perspectives and new surgical approaches with particular reference to advanced laparoscopic surgery: indications, timing, surgical techniques and application protocols. 35 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , RF Global ingestion by foodstuffs of some toxic contaminants: calculation of total exposure for every balanced diet differing classes of Italian people for age, dietary systems and clinical conditions. 35 biomedica Veterinary Food Safety FOSA , GR Population based epidemiology of early acquired disabilities: to qualify and quantify the unmet care needs of disabled individuals, to explore their avoidability to field test innovative interventions. 35 clinico assistenziale Population Sciences and Epidemiology , RF VIRO IMMUNOLOGICAL FACTORS INVOLVED IN THE POST LIVER TRANSPLANT HCV RE INFECTION AND IN THE RESPONSE TO SUBSEQUENT ANTIVIRAL TREATMENT 35 biomedica Infectious Diseases and Microbiology , RF Prematurity and low birth weight: probable cause of increased cardiovascular risk in adulthood 35,25 biomedica Cardiovascular and , GR Screening for Hereditary Hemochromatosis on Blood Donors from Lazio 35,5 clinico assistenziale Genes, Genomes and ,00 Pagina 241 di 244

242 2732 GR Minimally Invasive Thoracic Surgery 35,5 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering , GR EVALUATION AN INTERVENTION MEASURES ON QUALITY OF LIFE OF CHILDREN BORN WITH ANO RECTAL MALFORMATION 35,5 clinico assistenziale Biobehavioral and Behavioral Processes , RF GENOMICS AND METABOLOMICS PROFILINGS OF MYELODYSPLASTIC SYNDROMES AND MULTIPLE MYELOMA 35,5 biomedica Genes, Genomes and , RF Project MOICA Integrated Model of Continuity of Care between hospital and social setting of Primary Health Care (PHC) for problems and Alcohol related harm 35,67 clinico assistenziale Risk, Prevention and Health Behavior , RF Platelet aggregation tests in diabetic patients in clinical practice 35,67 clinico assistenziale Cardiovascular and , RF Prevention of Worsening of Chronic Disease and Drug Drug Interaction by A Simple Tool in Postmenopausal Women 36 clinico assistenziale Healthcare Delivery and Methodologies , RF Myocardial infarction and remodeling: at the heart of the problem 36 biomedica Cardiovascular and , RF HIGH DOSE RATE BRACHYTHERAPY WITH OR WITHOUT EXTERNAL BEAM RADIATION THERAPY IN PATIENTS WITH PROSTATE CANCER 36,25 clinico assistenziale Oncology 2 Clinical , GR Efficacy of a new multisensory stimulation in SV and SMC patients. 36,25 clinico assistenziale Brain Disorders and , GR Microarray as diagnostic tool to risk assessment in alimentary field; development, standardization and validation of multidiagnostic platforms to monitor bacteria and fungal pathogens in food. 37 biomedica Veterinary Food Safety FOSA , GR Autosomal Recessive Spastic Ataxia of Charlevoix Saguenay: functional study of the gene and its role in the pathogenesis of neurodegeneration autophagymediated 38 biomedica Molecular, Cellular, and Developmental Neuroscience ,00 Pagina 242 di 244

243 2743 GR Deregulation of methylation in X linked brain expressed genes and correlation with structural and functional brain abnormalities in patients with Idiopathic Autism Spectrum Disorders 38 biomedica Genes, Genomes and , RF Mutations and/or Polymorphism in vitamin D pathway genes,vitamin D levels and allergic asthma 39 biomedica Cardiovascular and , RF The use of probiotics as factors to improve the immune response of vaccines administered during epidemic emergencies. Identification of the animal model and utilize of anthrax vaccine for human use. 39 biomedica Immunology , RF Development of techniques and methods for diagnosing and treating nephrolithiasis. 40 clinico assistenziale Digestive, Kidney and Urological Systems , RF CONI Project:Relationship between metabolic diseases, lifestyle and nutrition in childhood 40 clinico assistenziale Endocrinology, Metabolism, Nutrition and Reproductive Sciences , RF Outcome research in oncology: a prospective study evaluating the effectiveness of different treatments and strategies in cancer patients 40 clinico assistenziale Healthcare Delivery and Methodologies , GR Monitoring and molecular characterization of vector insect population on sicilian territory and research of viral agents to them potentially associated 40 biomedica Infectious Diseases and Microbiology , GR Bone Marrow Cell Transplantation in Acute Anterior Myocardial Infarction Patients 40,5 clinico assistenziale Cardiovascular and 0, RF Team Mental Model: a new measurament performance methods to evaluate a social health services that are interdependent and organised as an Hub&Spoke Network. 40,5 clinico assistenziale Healthcare Delivery and Methodologies , GR EVALUATION OF IMMEDIATE, M TERM AND LONG TERM RENAL FUNCTION DAMAGE FOLLOWING DIFFERENT NEPHRON SPARING TECHNIQUES (OPEN NEPHRON SPARING SURGERY, LAPAROSCOPIC/ROBOTIC NEPHRON SPARING SURGERY AND LAPAROSCOPIC RENAL CRYOABLATION) 41 clinico assistenziale Surgical Sciences, Biomedical Imaging, and Bioengineering ,00 Pagina 243 di 244

244 2753 GR Automatic method for hepatic lesions extraction from multiphase CT images: a new approach for the assessment of the lesions response to therapy. 41,34 biomedica Surgical Sciences, Biomedical Imaging, and Bioengineering , GR Adiponectin involvement in the proliferation and differentiation of human glioblastoma tumor stem cells. 42 biomedica Oncology 1 Basic , GR INVASION MECHANISMS OF BRAIN TUMOR STEM CELLS 44 biomedica Oncology 1 Basic Pagina 244 di 244