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1 Big Data in Health-Care als Innovationstreiber Von in-vitro-diagnostik zu in-algorithmo-diagnostik Dr. med. Tobias D. Gantner, MBA, LL. M. HealthCare Futurists GmbH

2 Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 2

3 Flying high with drugs: How other markt participants have already challenged and changed established markets and business models Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 3

4 In Healthcare and Life Sciences the Challange Gains another Dimension Medical Profession Safety Regulation Evaluation Obstacles in Reimbusements Quantified Self Consumer Board Certified Knowledge Monopoly Primary Healthcare Market Dr. Google with 40 Mio. Calls Secondary Healthcare Market Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 4

5 Patient Reality Check: 87 y/o female, Alzheimer s: 31 prescriptions, 16 different medications per day. 51 y/o male, COPD: 37 prescriptions, 15 different medications per day. 85 y/o male, Autoimmune disease: 40 different medications = 56 pills per day. Compliance is not easy! Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 5

6 Compliance is a Function of the Whole Value Chain in Patient Health Independent Datatrustee Industry Physician Pharmacy Caregiver Sickfund Academia Gov nt Service Provision Supervisor? Industry/ Research Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 6

7 ishrine the Care-Cockpit for the Empowered SNOWWHITE S MIRROR ON STEROIDS THE HEALTH&SELFCARE HUB AND MEDICAL DISPLAY-INTERFACE WITH SERVICE INFRASTRUCTURE ishrine: The One Access Point for all things you. Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 7

8 Data is the new Oil: Data Driven HealthCare will enhance Life Sciences & Medicine courtesy of and Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 8

9 90% aller Patienten mit Defibrillator benötigen diesen gar nicht. Morphologische Variabilitäten haben große Aussagekraft, sind jedoch mit dem Auge nicht wahrnehmbar. Der Unterschied zwischen MV Trägern und Nicht-Trägern ist in der Absterberate statistisch signifikant. Die Lücke zwischen den beiden Kurven wird als Hazard-Ratio bezeichnet und liegt bei statistischer Signifikanz von p<0,001 bei knapp 33% computationally generated Biomarkers Decision Support Systems Eine multivariate Analyse ermöglicht es noch weitere Risikopatienten herauszufiltern. Source: NEJM Oct Do ICD s save lives?; MIT Guttag Research Group Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 9

10 HeartMine the Heart of Gold 3D ECG Monitor Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 10

11 HeartMine the Heart of Gold 3D ECG Monitor Wearable Technology, one lead touchpoint Preliminary Studies point to higher sensitivity than classic ECG Computer generated Biomarkers make broader analysis possible Readout through Predictive Algorithms 24/7 surveillance / data collection Better and quicker localisation of damages Online and offline interface to Physicians Reimbursement stategy for public market Currently undergoing clinical studies First Target market: Retailer Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 11

12 San Francisco Traffic Brain DSA Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 12

13 IS DATA DONATION A MORAL OBLIGATION SUCH AS ORGAN DONATION? Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 13

14 Leipzig, Berlin, Oct th, 2015 Big Data Driven TED HealthCare x HHL -als Tobias Innovationstreiber Gantner - Why Berliner we need Krankenhausseminar to empower Patients Slide Backgroundimage courtesy of Shutterstock

15 Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 15

16 Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 16

17 Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 17

18 Guessing Subjective Paternalism Believe Self HighPriest Faith Emotio Divinity The Patient Journey Predicting Objective Empowerment Know Others Physician/Scientist Prove Ratio BigData Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 18

19 430 bc PRESCRIPTIVE MEDICINE Cure what happened/is happening Eminence based medicine Establishment based medicine PROVIDER (PHYSICIAN) Prescription form, paternalism CONSUMER (PATIENT) Outsource to therapeutic action (drug, device, doctor) PAYER Insurance 2050 ac Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 19 Image courtesy of Shutterstock

20 2300 bc PARTICIPATIVE MEDICINE Share and Care Engagement Based Medicine Provider Mutual cooperation of physician and patient; time consuming; trust necessary Payer not always completely reimbursed Image courtesy of Shutterstock... ac Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 20

21 2300 bc PREVENTIVE MEDICINE Care before cure for what is developing Evidence Based Medicine PROVIDER (INSURANCE) Sports program, dental program; CONSUMER (POT. PAT.) Consent; activation, responsibility PAYER partim insurance, partim self pay... ac Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 21 Image courtesy of Shutterstock

22 1830 ac PREDICTIVE MEDICINE Based upon statistic methodes... ac Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 22

23 1830 ac PREDICTIVE MEDICINE Care for what might happen before it happens Emergence Based Medicine Provider (Methodology): in-algorithmo-diagnostics, Big Data Driven Healthcare Consumer (collective of pot. pats.): data access, data donation, right to know, sustainability, health education and literacy Payer: self pay (eg. 23&me)... ac Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 23 Image courtesy of 23&me

24 2013 ac PREEMPTIVE MEDICINE Take care of what will happen Empowerment Based Medicine Enlightnment based Medicine PROVIDER (LIFESCIENCES) Probabilities, statistics, heuristics, Med. Consultants CONSUMER (INDIVIDUALS) eg. Angelina Jolie; financial allocation; priv. insurances PAYER Self pay due to HTA evidence challenges Executes predictive Medicine... ac Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 24 Image courtesy Angelina Jolie

25 DISRUPTIVE MEDICINE Changing Roles in Health-Care: Providers, Payers, Physicians Good and bad used to be so easy to tell apart. Immense Pressure for homogeneity Break out and break through solutions Empowerment for patients and roll change Courtesy Lucasfilms/Disney Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 25

26 WHERE DOES INNOVATION COME FROM? FROM DEMOCRATIZATION Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 26

27 Courageous Penguin Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 27

28 Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 28

29 DON T BELIEVE EVERYTHING YOU THINK. Berlin, Big Data Driven HealthCare als Innovationstreiber Berliner Krankenhausseminar 29