da Vinci and Beyond Simon DiMaio, Ph.D. Intuitive Surgical 21 July 2014
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1 da Vinci and Beyond Simon DiMaio, Ph.D. Intuitive Surgical 21 July 2014
2 Medical Robots as Products Radio- Therapy Robots Robotic Assistants Tele- Robots MEDICAL ROBOTICS Imaging Robots Image- Guided Robots July 2014 North American Summer School on Surgical Robotics Slide 2
3 The Anatomy of a TeleRobotic System Surgeon Console Control System Patient-Side Manipulator July 2014 North American Summer School on Surgical Robotics Slide 3
4 The Anatomy of a TeleRobotic System (Sensei, Hansen Medical) Surgeon Console Control System Patient-Side Manipulator July 2014 North American Summer School on Surgical Robotics Slide 4
5 The da Vinci System in Motion July 2014 North American Summer School on Surgical Robotics Slide 5
6 Manual Laparoscopy (1980 s) Dr. Philippe Mouret ~ 1987 Credited with first lap chole procedure in France in 1987 Laparoscopic oophorectomy (removal of the ovaries) ~ early 1990 s July 2014 North American Summer School on Surgical Robotics Slide 7
7 21-25 July 2014 North American Summer School on Surgical Robotics Slide 8
8 21-25 July 2014 North American Summer School on Surgical Robotics Slide 9
9 1980 s Advancements in Robotics 1980 s offered tremendous advancements in microelectronics and computing. Robotic telepresence technology began to reach new heights (and depths). Deep Sea Robotics ~ 1985 Nuclear material robotic arm ~ 1981 Robot Jason Jr. Titanic wreck ~ 1986 NASA Robotic Arm ~ July 2014 North American Summer School on Surgical Robotics Slide 11
10 Robotics meets Surgery In the 1990 s, several groups recognized the opportunity to use tele-robotic technology to overcome laparoscopic challenges: July 2014 North American Summer School on Surgical Robotics Slide 12
11 First Surgical Console and Patient-side Manipulators (1996) July 2014 North American Summer School on Surgical Robotics Slide 13
12 The da Vinci Si Surgical System Patient Side Cart EndoWrist Instruments Vision Cart Surgeon Console Surgeon Console July 2014 North American Summer School on Surgical Robotics Slide 14
13 The da Vinci Xi (April 2014) July 2014 North American Summer School on Surgical Robotics Slide 15
14 What value can MIS offer to the Patient? Reduced pain. Reduced scarring. Reduced blood loss. Fewer complications. Faster return home, to work, and to normal activity. Fewer side effects (incontinence, impotence, infertility). Better cancer diagnosis and control (sometimes) July 2014 North American Summer School on Surgical Robotics Slide 16
15 What value can MIS offer to the Patient? Reduced pain. Reduced scarring. Reduced blood loss. Fewer complications. Faster return home, to work, and to normal activity. Fewer side effects (incontinence, impotence, infertility). Better cancer diagnosis and control (sometimes) July 2014 North American Summer School on Surgical Robotics Slide 17
16 Focus Procedure Areas >500,000 da Vinci procedures performed in 2013 Cardiothoracic Mitral Valve Repair Coronary Revascularization Lobectomy lung cancer Urology Prostatectomy prostate cancer Nephrectomy kidney cancer Cystectomy bladder cancer Pyeloplasty kidney reconstruction Gynecology Hysterectomy benign and endometrial cancer Sacral Colpopexy pelvic floor reconstruction Myomectomy removal of debilitating fibroids General Surgery Lower Anterior Resection colorectal cancer Head and Neck Surgery Trans-oral Robotic Surgery (TORS) throat and base-of-tongue cancer July 2014 North American Summer School on Surgical Robotics Slide 19
17 Open vs MIS trends in the US: Malignant Hysterectomy da Vinci primarily displaces open surgery Prevalence of lap hysterectomy for cancer less than 15% at its peak Open surgery is now used in only about 20% of surgeries for cancer July 2014 North American Summer School on Surgical Robotics Slide 20
18 Open vs MIS trends in the US: Benign Hysterectomy da Vinci primarily displaces open surgery After the introduction of da Vinci, the prevalence of MIS (lap, vaginal and da Vinci) grew. Open surgery is now used in only about 20% of benign hysterectomies July 2014 North American Summer School on Surgical Robotics Slide 21
19 da Vinci Platform Evolution da Vinci Xi Multi-quadrant access Chip-on-tip 3D HD vision 1999 da Vinci Si Dual Console option SKILLS SIMULATOR PATIENT-SIDE SKILLS INTEGRATED ENERGY da Vinci S 3D HD Vision FIREFLY SINGLE-SITE TABLE INTEGRATION (FUTURE RELEASE) SINGLE PORT SURGERY (FUTURE RELEASE) da Vinci Robot-assisted MIS Introduction of 4 th arm (2003) ADVANCED INSTRUMENTATION SYSTEM NETWORKING July 2014 North American Summer School on Surgical Robotics Slide 28
20 Observations Platform iterations take a long time. Add-on technologies iterate faster. A shift to multiple-platforms is imminent. Question: What factors have driven evolution directions? July 2014 North American Summer School on Surgical Robotics Slide 29
21 Design Drivers The OR environment. The team of users. Intended clinical indications. Some trade-offs: Usability (surgeon vs assistant vs OR staff) Versatility (procedures, indications, patients) Surgical performance Size Cost what else? July 2014 North American Summer School on Surgical Robotics Slide 30
22 This is a media photograph! July 2014 North American Summer School on Surgical Robotics Slide 31
23 This is reality: the OR environment July 2014 North American Summer School on Surgical Robotics Slide 33
24 This is reality: the OR environment July 2014 North American Summer School on Surgical Robotics Slide 34
25 This is reality: the OR environment July 2014 North American Summer School on Surgical Robotics Slide 35
26 This is reality: the environment July 2014 North American Summer School on Surgical Robotics Slide 36
27 A Team of Users surgeon circulating nurse (non-sterile) anesthesiologist There are several users. The work is highly collaborative. Different levels of familiarity with the system. assistant (sterile) surgical tech (sterile) July 2014 North American Summer School on Surgical Robotics Slide 38
28 Back to basics: Components of Surgery Preparation operating room, patient, equipment Access incision, insufflation, cannulation, (re)docking Exposure manipulation, retraction, dissection Assess visualization, palpation Resection transection, clamping/sealing, cutting, hemostasis Removal suction, morcellation Reconstruction suturing, stapling, fusing, anchoring Closure July 2014 North American Summer School on Surgical Robotics Slide 39
29 Back to basics: Components of Surgery Preparation operating room, patient, equipment Access incision, insufflation, cannulation, (re)docking Exposure manipulation, retraction, dissection Assess visualization, palpation Resection transection, clamping/sealing, cutting, hemostasis Removal suction, morcellation Reconstruction suturing, stapling, fusing, anchoring Closure Impact on the OR: Patient positioning Size and mobility Impact on workflow Procedure flexibility July 2014 North American Summer School on Surgical Robotics Slide 40
30 Impact on the OR Design philosophy: one cart multiple procedure applications. Trade-offs: Size, Versatility, Modularity, Ease of setup Si-e Xi Sp July 2014 North American Summer School on Surgical Robotics Slide 41
31 Impact on the OR Design philosophy: one cart multiple procedure applications. Trade-offs: Size, Versatility, Modularity, Ease of setup Alf-X SOFAR Xi July 2014 North American Summer School on Surgical Robotics Slide 42
32 Architecture of the Xi Cart and Gantry Casters Fixed drive wheels July 2014 North American Summer School on Surgical Robotics Slide 43
33 Architecture of the Xi Arms July 2014 North American Summer School on Surgical Robotics Slide 44
34 Impact on the workflow: Guided Set Up video July 2014 North American Summer School on Surgical Robotics Slide 45
35 Impact on the workflow: Guided Set Up video July 2014 North American Summer School on Surgical Robotics Slide 46
36 Impact on workflow: Avoiding Buttons video July 2014 North American Summer School on Surgical Robotics Slide 50
37 Bringing it all together: Rapid Setup Video (3x, 90 seconds actual) July 2014 North American Summer School on Surgical Robotics Slide 51
38 Back to basics: Components of Surgery Preparation operating room, patient, equipment Access incision, insufflation, cannulation, (re)docking Exposure manipulation, retraction, dissection Assess visualization, palpation Resection transection, clamping/sealing, cutting, hemostasis Removal suction, morcellation Reconstruction suturing, stapling, fusing, anchoring Closure Surgical field: Multiple ports Single port Natural orifice Number of quadrants Range of motion July 2014 North American Summer School on Surgical Robotics Slide 52
39 Workspace Flexibility Trade-offs: multi- vs. single-incision range of motion vs. rapid multi-quadrant July 2014 North American Summer School on Surgical Robotics Slide 53
40 Multi- vs Single-port Access Not available for sale. In development July 2014 North American Summer School on Surgical Robotics Slide 54
41 21-25 July 2014 North American Summer School on Surgical Robotics Slide 55
42 SingleSite Access with Multiport Platform July 2014 North American Summer School on Surgical Robotics Slide 56
43 Back to basics: Components of Surgery Preparation operating room, patient, equipment Access incision, insufflation, cannulation, (re)docking Exposure manipulation, retraction, dissection Assess visualization, palpation Resection transection, clamping, cutting, hemostasis, sealing Removal suction, morcellation Reconstruction suturing, stapling, fusing, anchoring Closure Surgical capability: Dexterity and precision Range of motion Stiffness and force Number of instruments July 2014 North American Summer School on Surgical Robotics Slide 57
44 Surgical Capability Trade-offs: Rigid versus flexible Wristed versus non-wristed Surgeon autonomy (how many hands?) July 2014 North American Summer School on Surgical Robotics Slide 58
45 Surgical Capability: Not just instruments video * Product feature not yet available. In development July 2014 North American Summer School on Surgical Robotics Slide 60
46 Back to basics: Components of Surgery Preparation operating room, patient, equipment Access incision, insufflation, cannulation, (re)docking Exposure manipulation, retraction, dissection Assess visualization, palpation Resection transection, clamping, cutting, hemostasis, sealing Removal suction, morcellation Reconstruction suturing, stapling, fusing, anchoring Closure Surgical guidance: Sensing/Feedback Decision support Navigation July 2014 North American Summer School on Surgical Robotics Slide 62
47 Surgical Guidance & Decision-making Fluorescence imaging Open opportunities: Image guidance? Haptics, Palpation? July 2014 North American Summer School on Surgical Robotics Slide 63
48 Advanced Imaging: Fluorescence Imaging July 2014 North American Summer School on Surgical Robotics Slide 64
49 Augmented Vision: The Image-Guided Surgical Cockpit July 2014 North American Summer School on Surgical Robotics Slide 65
50 Back to basics: Components of Surgery Preparation operating room, patient, equipment Access incision, insufflation, cannulation, (re)docking Exposure manipulation, retraction, dissection Assess visualization, palpation Resection transection, clamping, cutting, hemostasis, sealing Removal suction, morcellation Reconstruction suturing, stapling, fusing, anchoring Closure Tissue interaction: Specialized instruments Interchangeable instruments July 2014 North American Summer School on Surgical Robotics Slide 66
51 Trade-offs Tissue Interaction Diameter versus functionality & performance Ability to exchange instruments quickly Single versus multi-use Cost July 2014 North American Summer School on Surgical Robotics Slide 67
52 Advanced Instruments EndoWrist One Vessel Sealer July 2014 North American Summer School on Surgical Robotics Slide 68
53 Advanced Instruments Endowrist Stapler July 2014 North American Summer School on Surgical Robotics Slide 69
54 Back to basics: Components of Surgery Preparation operating room, patient, equipment Access incision, insufflation, cannulation, (re)docking Exposure manipulation, retraction, dissection Assess visualization, palpation Resection transection, clamping/sealing, cutting, hemostasis Removal suction, morcellation Reconstruction suturing, stapling, fusing, anchoring Closure Impact of Platform Trade-offs July 2014 North American Summer School on Surgical Robotics Slide 70
55 Platform Trade-offs SIMPLE/BENIGN CASES OPEN COMPLEX CASES da Vinci Si Support for Single-Site & Some Complex Cases da Vinci Si-e Designed for Single-Site* & Simple Cases da Vinci Xi and Sp Optimized for Complex Cases July 2014 North American Summer School on Surgical Robotics Slide 71
56 Opportunities: Ideals in Surgery 1. See disease perfectly. 2. Resect diseased tissue, spare healthy tissue. 3. Reconstruct with precision. 4. Leave as if no surgery was required July 2014 North American Summer School on Surgical Robotics Slide 72
57 Opportunities: How is technology taking us closer to the Ideal? Surgeon Console Control System Patient-Side Manipulator July 2014 North American Summer School on Surgical Robotics Slide 73
58 The Software in the Middle Surgeon Console Control System Patient-Side Manipulator Stabilize Augment Scale Extend Navigate Anticipate Warn Automate Guide July 2014 North American Summer School on Surgical Robotics Slide 74
59 Our Technology Development Focus Surgeon Training Advanced Imaging New Platforms Advanced Instrumentation July 2014 North American Summer School on Surgical Robotics Slide 75
60 The Role of Simulation video Pre-product visualization. Product preview. Console training. Patient-side training July 2014 North American Summer School on Surgical Robotics Slide 77
61 The Role of Simulation video Pre-product visualization. Product preview. Console training. Patient-side training July 2014 North American Summer School on Surgical Robotics Slide 78
62 Simulator Impact: Morristown Study Console Operative Times* Minutes Experienced Group Study Group Control Group (P = 0.12) (P < ) *All operative times were measured during a supracervical hysterectomy on patients with a 50 gm-or-less uterus Accepted for publication in Female Pelvic Medicine & Reconstructive Surgery; Dr. Patrick Culligan July 2014 North American Summer School on Surgical Robotics Slide 80
63 Some Challenges Complexity Regulation Litigation Cost July 2014 North American Summer School on Surgical Robotics Slide 83
64 Product Development Cost and Complexity It took ~9 years and >$250M for Intuitive to reach profitability R&D investment totaled $167 million, or ~$320 per patient. A da Vinci system is composed of >35,000 individual components (counting down to resistors) from >300 suppliers (direct). There are >2 million lines of embedded run-time code. Almost half of this code is related to safety and redundancy. A typical software verification will consist of ~40,000 test cases. The formally-maintained design history file is >10,000 pages of documentation July 2014 North American Summer School on Surgical Robotics Slide 84
65 Complexity: The Product Ecosystem da Vinci da Vinci S da Vinci Si da Vinci Si-e da Vinci Xi da Vinci Firefly da Vinci Single-Site da Vinci Skills Simulator Instruments (8mm: 44; 5mm: 12; 12mm: 1) Endoscopes (12mm & 8.5mm: 18) Accessories Cannulas, obturators, seals, drapes, sterile adapters, energy cables, sterilization trays, light guides, etc July 2014 North American Summer School on Surgical Robotics Slide 85
66 Challenges: Economic Cost vs. Value Direct Costs System capital expense, service contracts, and training. Instruments and accessories. Direct Savings Avoided supply costs and operating expenses (e.g., length of hospital stay). Reduced re-admissions costs (due to complications & recurrence). Overall health & quality of life outcomes, including Cancer control (effect on positive margin rates) Cancer diagnosis, improved lymph removal (malignant gynecology) Continence, potency (prostatectomy) Fertility (myomectomy) Avoided sternotomy (cardiac procedures) Reduced rate of dialysis (partial nephrectomy vs. full nephrectomy) Reduced pain during recovery (feeding tube for throat cancer surgery). Faster return to work and other normal activities. Avoided costs of expensive non-surgical therapies (e.g., radiation therapy). Reduced long-term capital investment (fewer beds built/maintained). Surgeon focus and productivity July 2014 North American Summer School on Surgical Robotics Slide 86
67 Challenges: Economic Cost vs. Value Minimally invasive procedures increased from 17% to 98% in 2 years Historic cohort n=160; Robotic cohort n=143 Robotic cohort: Longer OR time (233 vs 206 minutes) Fewer adverse events (13% vs 42%) Less blood loss (50 ml vs 200 ml) Reduced median hospital stay (1 vs 5 days) Lower overall hospital costs ($7644 vs $10,368) - with amortization/maintenance, ($8,370 vs $10,368) Reduced recurrence rates (11 cases vs 19) Lau et al. Jewish General Montreal July 2014 North American Summer School on Surgical Robotics Slide 87
68 Economic Analyses Same subject, same journal*, different conclusions Wright, et al Laparoscopic population Excludes open surgery Cost-to-charge and direct costs: Lap < robotic Conclusion: Lap less expensive than robotics for this subset of patients Leitao, et al Total population approach Includes open surgery 6-month direct costs: Lap < robotic < open Conclusion: By reducing open surgery, robotics yields savings on a population basis Direct, comprehensive cost analysis on a population basis yields a more accurate assessment of the cost-to-treat impacts for hospitals and the healthcare system overall. *Both studies published in May 2014 edition of Obstetrics & Gynecology evaluating uterine cancer July 2014 North American Summer School on Surgical Robotics Slide 88
69 What might the future hold? This was the Automobile roughly 15 years in July 2014 North American Summer School on Surgical Robotics Slide 89
70 The Future Through the Lens of Research July 2014 North American Summer School on Surgical Robotics Slide 90
71 The Future Through the Lens of Research July 2014 North American Summer School on Surgical Robotics Slide 91
72 The Future Through the Lens of Research Stoianovici et al, JHU Desai et al, U. Maryland July 2014 North American Summer School on Surgical Robotics Slide 92
73 The Future Through the Lens of Research Abbeel, Goldberg et al, UC Berkeley July 2014 North American Summer School on Surgical Robotics Slide 93
74 The Future Through the Lens of Research July 2014 North American Summer School on Surgical Robotics Slide 94
75 Concluding Thoughts Robots are just one part of a complex system. The overall goal is to enable greater shift to MIS. There are many system design trade-offs. User-centric design tries to balance the needs of a team of users. Different system architectures for different clinical needs. There are many opportunities, particularly in surgical guidance and decision support July 2014 North American Summer School on Surgical Robotics Slide 95
76 I N T U I T I V E S U R G I C A L July 2014 North American Summer School on Surgical Robotics Slide 96
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