Curriculum Vitae. Personal Details. Education and Qualifications

Transcription

1 1 Curriculum Vitae Name: Pedro Antonio Valdes-Sosa M.D., Ph.D., D.Sc. Place and Date of Birth: Chicago, Illinois EEUU/ 12 March 1950 Personal Details General Vice-Director for Research Cuban Neuroscience Center Senior Researcher, Senior Professor, Full Member Cuban Academy of Sciences Coordinator Cuban Brain Mapping Project Meeting Liaison Elect Organization for Human Brain Mapping Program Chair Organization for Human Brain Mapping Head of Oversea Team of 111 Project of the Key Laboratory for NeuroInformation,University of Electronic Science and Technology of China, Chengdu, , China Address: Ave 25 #15202 esq. 158 Cubanacan, Playa Apdo Habana 6 CP 10600, Cuba s: [email protected] [email protected] [email protected] Work Phone: (53) / Publications: Education and Qualifications 2011: D.Sc. Doctor in Science (Cuban higher degree after Ph.D.) 2008-present: Senior Professor of the Havana Higher Institute of Medicine. 1983: 2 nd Degree Specialist, Ministry of Public Health 1980-present: Senior Researcher : Postdoc training on Neurometrics and Compuational Techniques with Prof. E. Roy John at the Brain Research Lab of New York University USA : Postdoc training on Biophysical Modeling of brain electrical activity with E. Roy John at the Brain Research Lab of New York University USA

2 1974: Ph.D. at the National Center for Scientific Research of Cuba with the thesis: Stochastic Properties of Event Related Potentials 1974: Medical Specialist 1 st Degree Physiology, the higher degree (1980) : B.Sc. Faculty of Mathematics at the University of Havana : M.D. Faculty of Medicine at the University of Havana 2 Professional Experience Director of the National Program Neurobiology and Neuroscience of the Ministry of Science and Technology of Cuba. (Budget 120 million CUP) Member of scientific committee that oversaw the Complete-Population Studies of Disabilities in Cuba and Venezuela 1996 Expert at the World Health Organization WHO. International meetings Moscow, Russia and Geneva, Switzerland 1990: Co-founder of the Cuban Neuroscience Centre and its Research Director since then 1982; Founder and initiator of the Cuban National Hearing Screening Program : Deputy Head of Special Group for the Neurosciences, National Scientific Research Center, Cuba : Head of Department for Neurophysics and Neurocybernetics. Direction of Neurosciences. National Scientific Research Center, CNIC Cuba 1984 Expert at the World Health Organization WHO international meeting about early detection of brain damage 1983 Delegate of MEDICID group at the Biologic Front at the Cuban Academy of Sciences 1982 Coordinator of the Regional Project Cuba-Mexico-Venezuela of UNPD Expert at the INTERCOSMOS project to the meeting about "CORTEX" experiments. Visit to the Brain Experimental Institute of Leningrad, Rusia 1981: Present Co-Organizer of the National Network of Clinical Neurophysiology. Cuba 1981 President of the scientific multi-national commission to study technological and statistical bases of brain diseases of United Nations Regional Development Program UNDP 1981:1987 Advisor on EEG technologies for early detection of brain damage. Regional Project for Latin America UNDP 1979 Coordinator of the Regional Project Cuba-Jamaica-Barbados of UNPD. Jamaica 1979 Expert at the meeting about BIONICS of CAME (former organization of socialist countries for market and commerce) Berlin, German Democratic Republic 1980 Coordinator of Regional Project Cuba-Mexico-Venezuela of UNPD

3 : Director (Dean) of Post-graduate Studies. National Scientific Research Center CNIC Cuba : Head of the Computer Lab of the Department Neurophysiology, National Scientific Research Center, Havana Cuba : Head of the Computer Center in National Scientific Research Center, Havana Cuba Other functions Coordinator Latin American Brain Mapping Network LABMAN 2000-Present Full member of the Cuban Academy of Science Member of the Scientific Advisory Board of the Minister of Health of Cuba : Member National Committee for Scientific Degrees, Cuba Member General Scientific Council, National Scientific Research Center, CNIC Cuba Co-Organizer of the National Network of Clinical Neurophysiology Present Full Member of the Latin American Academy of Science 1979:2000 Expert at the United Nations Development Program UNPD 1996 Expert at the World Health Organization WHO Invited/Honorary Professor 2011 Visiting Professor for Senior International Scientific of the Chinese Academy of Sciences 2010 Head of Oversees Team of Talent Introducing Base for Neuroinformation (111 Project) China 2006 Honorary Professor of University of College of London UCL, UK 1999 Invited Researcher of the Brain Science Institute RIKEN of Japan 1997 Invited Professor University of Illinois, Chicago 1995 Invited Professor of the Institute of Statistical Mathematics of Japan Main Fields of Scientific Activity 1. Initiated work with quantitative electrophysiology in 1969 with the first Cuban microcomputer for which he developed methods and software. 2. Introduction of these methods in health systems in Cuba and other countries. 3. Co-founder of the National Network for Clinical Neurophysiology 4. Developed Computational theory and methodology, for both EEG/MEG and fmri with contributions to multichannel EEG/MEG (from ) 5. Developed the Distributed ESI(Electrophysiological Source Imaging, (since 1989), 6. Applied the Statistical Parametric Mapping for modeling ESI (since 2000), 7. Granger Causality (since 1998)

4 8. Neuroimaging (fmri, EEG and MEG tomography) 9. Nonlinear dynamical modeling of brain function 10. Event-Related Brain Dynamics )since 2000) 11. Neural mass modeling (since 2009), 12. Neuroinformatic and Data Mining (since 2000) 13. Effective connectivity theory (since 2011) 4 Current Editorial Boards Audiology and Neurotology Neuroimage Philosophical Transaction of the Royal Society (Editor Special Issue 2004 Connectivity) PLosOne (Academic Editor) MEDICC review Brain Connectivity Frontiers Prizes and Awards Award to the best Doctorate Thesis in 2012 of the Academy of Sciences and Ministry of Higher Education of Cuba Granger causality on the determination of brain functional networks José Tey Award for dedication to Education of other professionals in Cuba Award of the World Intellectual Property Organization for Creativity and Inventions Award of the Ministry of Higher Education of Cuba Award of the Academy of Sciences of Cuba to the work Nonlinear Statistical Identification of the normal and epileptic brain Award of the Academy of Sciences of Cuba to the work Statistical Methods for Electrophysiological Neuroimages Award of the Academy of Sciences of Cuba to the work Three dimensional Mapping of EEG Source Spectra with a Special Recognition from the Minister of Science, Technology and Environment Carlos J. Finlay Award for Outstanding Scientific Merit Award of the Ministry of Higher Education of Cuba Award of the Academy of Sciences of Cuba to the work "Frequency Domain Models for the EEG" with a Special Recognition from the Minister of Science, Technology and Environment Award of the Academy of Sciences of Cuba to the work "Development of Technology and Equipment for the diagnosis of Brain Disease Award to the MEDICID neurometric equipment in the Fair Salud para Todos Havana Cuba

5 Annual Award of CNIC for Best Scientific Paper CAME exposition Moscow, USSR: Bronze Medal for MEDICID family of Computerized Neurophysiologic Systems Award Ministry of Public Health for Best Scientific Contribution for Frequency Domain Models of the EEG Grants and Funding The Atlantic Charitable Trust (2010) Stratified Active Screening for Neurodevelopmental Disorders 350,000.0 USD Grant from the Council on Early Child Development of Canada 2006 (35, USD) Human Science Frontier Program HSFP Oscillations and brain 1998/2000 (90,000 USD) United Nations Program for Development UNDP 2004 (200,000 Euros) Professional Memberships Cuban Society Physiological Sciences (1974-) Cuban Society for Biological Sciences (1979-) Cuban Neuroscience Society (1989-). President of Neurocybernetics Section ) Cuban Mathematical Society (1983-) Cuban Society for Clinical Neurophysiology (1990-). President Latin American Society for Clinical Neurophysiology (Board of Chapter of Latin America CLA) Member of International Society of Clinical Neurophysiology Cuban Society for Bioengineering. (1979-) Cuban Society for Physics: Biophysics Section (1990-) International Society for Brain Electrical and Magnetic Topography ISBET. Member Scientific Advisory Board Organization for Human Brain Mapping (Member since 1999) Meeting Liaison Elect ( ) International Collaboration (examples for countries) France: Mireille Besson from University of Aix-Marseille and CNRS Mediterranean; Bertrand Renault, Catherine Tallon-Baudry, Francisco Varela, Mario Chavez, at the MEG-EEG Center of the Hospital Pitié-Salpétrière and Centre National Recherche Scientific CNRS Paris; Jean-Batiste Poline. NeuroSpin; Viktor Jirsa, Cristian Bernard from Theoretical Neuroscience Group, CNRS Mediterranean.

6 6 Canada: Alan C. Evans, Professor of Neurology, McGill University/Montreal Neurological Institute. Director of the Montreal Consortium for Brain Imaging Research, Montreal; Terence Picton, Rotman Institute Toronto; Maryse Lassonde and Franco Lepore, Centre for Cognitive Research at U- Montreal, Montreal; Stuart Shanker and Jim Stuart in Toronto, collaboration through the Council on Early Child Development, an initiative that seeks to increase the quality of life and potential of disadvantaged children in Canada and worldwide. Japan: Tohru Ozaki, Institute Statistical Mathematics, Tokio; Ryuta Kawashima from Tohoku University, Sendai; Masao Ito and Yoko Yamaguchi at Rikken Institute, Tokio. Mexico: Thalia Harmony and Antonio Fernandez-Bouza, at the Institute of Neurosciences in Queretaro Mexico United States of America: Erwin Roy John and Leslie Pritchep Brain Research Lab New York University; Steven Hylliard, Antigona Martinez UCLA; Mark Razenik Univ. Chicago. England: Karl Friston and Brian Butterworth UCL UK Italy: Fabio Babiloni, University La Sapienza Roma; Aldo Spallone Surgery Clinic Roma; Institute of Rehabilitation Santa Lucia Roma Germany: Jens Franz, Rolf Kotter and Kamil Uludag from Max-Planck Institute Germany; Niels Birbaumer from Institute of Medical Psychology and Behavioral Neurobiology Univ. Tübingen; Tomas Elbert University Konstanz Germany (joint grant proposal Human Science Frontier Program) Other countries: Silvia Kochen from Epilepsy Unit at the University of Buenos Aires, Argentina for the source analysis of epileptic discharges in the continuous EEG. Andrew Janke, Michael Breakspear, Australia; Fernando Lopes Da Silva, Netherlands; Mathias Muller, Tomas Gruber, Switzerland. Post-graduate Courses Taught Educational Course at Connectivity Workshop Effective Connectivity in the Study of Brain Networks Chengdu Cortical Processing and Neural Imaging. Universiti Sains Malaysia, Penang EEG Signal Processing Course. Universiti Sains Malaysia, Kota Baru Multimodal Integration of functional brain measures. Lutherstad, Wittenberg Germany Neuroimaging and Neuroinformatics. International Program: Master in Clinical Neuropsychology. Instituto Altos Estudios Universitarios IAEU. Spain 2004-Present Methods in Neuroimaging, Electro-Magnetic Tomography and Neuroinformatics at the Program for Master Degree in Neurosciences at the Cuban Neuroscience Center, Habana Cuba Introduction to Neuroinformatics. Autonomous University of Madrid Spain

7 Fifth International Conference on functional mapping of the Human Brain and 1989-Present Educational Brain Mapping Course, Germany Analysis of the Electrical and Magnetic Signals of the Brain. Program for Clinical Neurophysiology residents at the Cuban Neuroscience Center, Habana Cuba 1983: EEG Signal Processing. National Autonomous University of Mexico UNAM 1982: Multivariate Time Series Analysis. National Autonomous University of Mexico UNAM 1981: Introduction to Neurometrics. National Autonomous University of Mexico, UNAM 1978: Multivariate Statistics. CNIC Introduction to Biomedical Computing. CNIC Academic Supervision Since 1977: mentor and advisor of more than 20 postgraduate students Since 2006: Advisor of Degree theses at the Cognitive Neuroscience Master Program at the Cuban Neuroscience Center Gertrudis de los Angeles Hernandez: Neural bases of human intelligence Lupe Liudmila Rodriguez: DTI and reaction time Yaritza Recio DTI and intelligence 1985-on: PhD thesis advisor of 14 scientific researchers 1. Jose M. Sanchez Bornot (2010) Regression methods to evaluate high dimensionality data in EEG and fmri 2. Lester Melie (2010) Mathematical physical models for the characterization of the microstructure of biological tissues in vivo from MRI 3. Nelson Trujillo Barreto (2009) Bayesian model to analysis and integration of functional neuroimaging 4. Eduardo Martinez Montes (2009) Characterization of space-time-frequency of the electric activity of neurons networks 5. Eduardo Aubert-Vazquez (2000) System for the Visualization of the Electrical Activity of the Brain 6. Jorge Bosch-Bayard (2000) High Resolution quantitative EEG Analysis 7. Lídice Galán-Garcia (2000) Statistical Methods for the Comparison of Topographic and Tomographic Brain Maps 8. Jorge J. Riera-Diaz (1999) Direct and Inverse EEG/MEG Problems: New approaches 9. Rolando Biscay-Lirio (1998) Measuring the Accuracy of Medical Imaging 10. Juan Teijeiro-Garcia (1997) Computerized System for Recording Deep Structures of the Brain as a Guide for Functional and Stereotaxic Surgery

8 8 11. José L. Hernández Cáceres (1996) Nonlinear Methods in Quantitative Electroencephalography 12. Roberto D. Pascual-Marqui (1988) Multivariate Modeling of the EEG in the Frequency Domain 13. Alfredo Alvarez Amador (1987) Quantitive Análisis of EEG maturation 14. Mitchell Valdés-Sosa (1985) Detection of Hearing Loss in Newborns by means of Brain Stem Auditory Evoked Responses. Post-doctoral students: Consultant for Fumikazu Miwakeichi (Advisor Tohru Ozaki, ISM) 2000 Japan Tomas Koenig from University Hospital of Psychiatry (UPD) Bern, Switzerland Invited Conferences (more representatives) - Development of neurometric methods in Cuba. Valdés P. XXIV International Conference. Wissenchafuches Kolloquium der Techischen Hoschule Ilmenau. Germany Statistical Bases of Neurometrics. Valdés P. I Symposium Internacional sobre daño Cerebral, Toluca, México, The Accuracy of EEG Topographic Maps on Neurological Lesions. Valdés P., Figueredo P., Antelo J., Biscay R., Galán L. XII International Congress of Electroencephalography and Clinical Neurophysiology, Río de Janeiro, Brazil, January High Resolution Spectral EEG Norms for Topography. Valdés P., Biscay R., Galán L., Bosch J., Szava S., Virues T. The First International Congress on Brain Electromagnetic Topography. Osaka, Japan. September 12-14, Análisis Computarizado del EEG y Potenciales Evocados. Valdés P. Facultad de Ciencias Medicas Universidad Estatal de Campinas (UNICAMP), Brazil, 4 de Julio, EEG in a Public Health System. Valdes P. Symposium: Clinical Utility of Discriminant Classification in EEG. In The Second International Congress on Brain Electromagnetic Topography. July 29 - August 1. Toronto Canada, Frequency Domain Models of the EEG. Valdés P. Symposium: Advances in EEG. In The Second International Congress on Brain Electromagnetic Topography. July 29 - August 1. Toronto Canada, Source Localization of the EEG Spectrum. Valdés P., Grave de Peralta R., Pascual R. In The Second International Congress on Brain Electromagnetic Topography. July 29 - August 1. Toronto Canada

9 9 - A General Scale Factor for EEG Topography. Valdés P., Hernandez J., Pascual R. In The Second International Congress on Brain Electromagnetic Topography. July 29 August 1. Toronto Canada The Fractal Transform for modeling Dynamic EEG Topography. Valdés P., Pascual R., Biscay R., Castellanos M., Pérez L., Echevarría M. In The Second International Congress on Brain Electromagnetic Topography. July 29 - August 1. Toronto Canada Event Related Incongruence Components: Source Analysis in the Frequency Domain. Valdés P. Tenth International Conference on Event Related Potentials of the Brain. May 31-June 5, Hungary EEG Source Norms. Bosch J., Valdés P., Riera J., Aubert E., Virues T. and Riquenes A. III International Congress on Brain Electromagnetic Topography. Amsterdam June Measuring the Diagnostic Contribution of QEEG in Clinical Setting. Valdés P. MEDINFO'92., Geneva, Switzerland Sept EEG Analysis and Source Localization in the Frequency Domain. P. Valdes Sosa. Special Lecture. Rotman Institue, Toronto Nonlinear Quantitative EEG Analysis, P. Valdes, J.L. Hernandez, R. Biscay, R. Grave de Peralta, A. Gonzalez, J.L. Valdes, XIIIth International Congress of Electroencephalography and Clinical Neurophysiology, Vancouver, Canada, August 29-September 4, Brain Electromagnetic Tomography: Bases and Clinical Application. P. Valdés Sosa. II Latin American Congress of Clinical Neurophysiology. Buenos Aires, September And other invited conferences at McGill University, Montreal Neurological Institute, University of Montreal Canada, Welcome Neuroimaging Lab UCL London, Istanbul, Turkey; Australia, Germany; Netherland; India; Finland. International Meetings and Workshops organized o Brain Connectivity Workshop. Chengdu, China 2012 (Co-organized with Michael Breakspear Australia, Dezhong Yao and Tianzi Jiang from China) o Key Symposia OHBM 2011 Quebec Canada o The Keith Worsley workshop on Computational Modeling of Brain Dynamics: from stochastic models to Neuroimages workshop at the Banff International Research Station for Mathematical Innovation and Discovery (BIRS) in Banff, Alberta, Canada, June 2009 (Coorganized with Victor Jirza CNRS Marseille). o 1st British-Cuban Workshop on Neuroimaging:Techniques and Applications. Havana Cuba 2006 (Co-organized with Karl Friston and Will Penny UCL, London UK)

10 10 o IX International Workshop on Wavelets, Differential Equations and Quantization. Surfaces Granger Causality on Spatial Manifolds: Applications to Neuroimaging Havana, Cuba 2006 o CUBA-USA INTERNATIONAL MEETINGS IN NEUROSCIENCE. Hotel Nacional, Havana Cuba (1999 and 2010) (Co-organized with Mark Razenick Univ. Chicago USA) o 4 th National Congress/1rst Ibero American Symposia in Clinical Neurophysiology Varadero 2008 o IBRO Summer International Workshop on Cognitive Neurosciences. Havana Cuba, 2007 o IX International Conference on Cognitive Neuroscience Estimating of Effective Brian Connectivity with EEG and fmri ICON Havana 2005 o Introductory Neuroinformatics Course at the Brain Connectivity Workshop. Havana Cuba 2004 o VI Congress of the Society of Latin American Neuropsychology SLAN Varadero Cuba 1999 o IV International Congress of the International Society of Brain Electromagnetic Topography (ISBET), Havana Cuba July 1993 Publications Book Chapters [1] P. Valdes-Sosa, J. Sánchez-Bornot, M. Vega-Hernández, L. Melie-Garcia, A. Lage-Castellanos, E. Canales-Rodriguez, Granger causality on spatial manifolds: applications to neuroimaging in Handbook of Time Series Analysis: Recent Theoretical Developments and Applications, Wiley- VCH, 2006, pp [2] P. Valdés, J. Bosch, J. C. Jiménez, N. Trujillo, R. Biscay, F. Morales, J. L. Hernández, T. Ozaki, The statistical identification of nonlinear brain dynamics: A progress report in Nonlinear Dynamics and Brain Functioning, N. Pradhan and P. Rapp, Eds. Nova Science Publishers, Inc., 1999, pp [3] T. Ozaki, P. Valdes-Sosa, and V. H. Ozaki, Reconstructing Nonlinear dynamics from time series: with Application to Epilepsy Data Analysis, in Nonlinear Dynamics and Brain Function, vol. 02, N. Pradhan and P. Rapp, Eds [4] T. Ozaki, J. C. Jimenez, R. J. Biscay, and P. A. Valdes, Nonlinear time series models and neural dynamical systems, in Nonlinear Dynamics and Brain Functioning, New York: Nova Science Publishers, Inc., [5] J. J. Riera, E. Aubert, P. Valdes-Sosa, R. Casanova, and O. Lins, Discrete spline electricmagnetic tomography (DSPECT) based on realistic neuroanatomy, Biomag 96. Proceedings of the Tenth International Conference on Biomagnetism, pp , 1996.

11 11 [6] R. Casanova, P. Valdes-Sosa, F. M. Garcia, E. Aubert, J. J. Riera, W. Korin, and O. Lins, Frequency domain distributed inverse solutions, Biomag 96: Proceedings of the Tenth International Conference on Biomagnetism, p. 189, [7] B. Luetkenhoener, R. Greenblatt, M. Hämäläinen, J. Mosher, M. Scherg, C. Tesche, and P. Valdes Sosa, Comparison between different approaches to the biomagnetic inverse problem, in Biomag 96: Proceedings of the Tenth International Conference on Biomagnetism, [8] P. Valdes-Sosa, R. Casanova, F. Marti, F. Garcia, J. Bosch, O. Lins, and J. Riera, Mixed Inverse solution with stochastic generators., in Biomag 96: Proceedings of the Tenth International Conference on Biomagnetism., S. J.. W. Aine C.J.; Okada G.; Swithenby C.C, Y.; Stroink, Ed. Springer Verlag, [9] P. Valdes-Sosa, F. Marti, L. Melie-Garcia, and R. Casanova, Variable Resolution Electric- Magnetic Tomography, in Biomag 96: proceedings of the Tenth International Conference on Biomagnetism: Volume I, Havana Cuba: [10] P. Valdes-Sosa, J. Riera, and R. Casanova, Spatio temporal distributed inverse solutions, in Biomag 96: proceedings of the Tenth International Conference on Biomagnetism: Volume I, C. J. Aine, Y. Okada, G. Stroink, S. J. Swithenby, and C. C. Wood, Eds. Springer, 1996, pp [11] J. J. Riera, P. A. Valdes-Sosa, and E. Aubert, Frequency Domain Distributed Inverse Solutions., in Biomag 96: Proceedings of the Tenth International Conference on Biomagnetism, 1996, vol. 2, pp [12] M. Valdés-Sosa, M. A. Bobes, C. Sierra, M. Echeverria, L. Perez, J. Bosch, and P. A. Valdés- Sosa, Attentional effects on image-motion related potentials and spectral perturbations in Oscillatory Event-Related Brain Dynamics, NATO ASI S., C. Pantev, Ed. Plenum Press, 1994, pp [13] A. Alvarez, R. Pascual, and P. A. Valdés-Sosa, Spatiotemporal properties of the Alpha Rhythm. in Machinery of the Mind Boston, MA: Birkhauser, 1990, pp [14] R. D. Pascual-Marqui, R. Biscay-Lirio, and P. A. Valdés-Sosa, The Physical Basis of Electrophysiological Brain Imaging : Exploratory Techniques for Source Localization and Waveshape Analysis of Functional Components of Electrical Brain Activity in Machinery of the Mind, Boston, MA: Birkahauser, 1990, pp [15] P. A. Valdes-Sosa, R. J. Biscay, and R. Biscay-Lirio, The Statistical Analysis of Brain Images in Machinery of the Mind, E. R. John, T. Harmony, M. Valdés-Sosa, and P. A. Valdés-Sosa, Eds. E. R. John, T. Harmony, M. Valdés-Sosa, and P. A. Valdés-Sosa, Eds. Boston, MA: Birkhauser, 1990, pp [16] E. R. John, T. Harmony, L. Prichep, and P. Valdes, Analysis of electroencephalographic maturation., in Machinery of the mind,, E. R. John, T. Harmony, M. Valdés-Sosa, and P. A. Valdés-Sosa, Eds. Boston, MA: Birkhauser, 1990, pp

12 12 [17] E. R. John, L. Prichep, T. Harmony, A. Alvarez, R. Pascual, A. Ramos, E. Marosi, A. E. Díaz De Leon, P. A. Valdés-Sosa, and J. Becker, Neurometric and behavioral studies of Normal and at risk children in several different countries in Perspectives on Dislexia Vol 1, 1990, pp [18] A. E. de Leon, P. Valdes, and J. Becker, Neurometric and Behavioral Studies, Perspectives on Dyslexia: Neurology, Neuropsychology and genetics, vol. 1, p. 119, [19] T. Harmony, E. Marosi, A. E. Diaz de Leon, J. Becker, A. Alvarez-Amador, R. Pascual-Marqui, P. A. Valdes-Sosa, and A. Ramos, Maturation of EEG in different groups of children, London: John Libey, [20] P. Valdes, R. Pascual, J. C. Jimenez, J. Carballo, R. Biscay, S. Gonzalez, J. L. Willens, J. H. Van Bemmel, J. Michel, P. A. Valdes-Sosa, S. Gonzalez-Andino, R. Biscay-Lirio, J. A. Carballo- Gonzalez, J. C. Jimenez-Sobrino, and R. Pascual-Marqui, Functionally based statistical methods for the analysis of the EEG and event related potentials, in Progress in computer-assisted function analysis, vol. Elsevier S, no. -, Amsterdam: Elsevier, 1988, p. 91. [21] T. Harmony, E. Marosi, A. E. Diaz de Leon, J. Becker, A. Alvarez-Amador, R. Pascual-Marqui, P. Valdes, and A. Ramos, Regresion en funcion de la edad de variables obtenidas a partir del analisis de frecuencias del elecroencefalograma en niños con distintas caracteristicas socioculturales., II Foro Nacional de Estadistica, Mexico, [22] A. Alvarez, A. Pascual, P. Valdes, and G. Otero, Estudio de la influencia de algunas variables biologicas sobre las caracteristicas del electroencefalograma, in Estudios Avanzados en Neurociencias, Habana Cuba, [23] A. Alvarez, P. A. Valdes-Sosa, G. Otero, R. Pascual-Marqui, J. Ricardo-Garcell, X. Garcia, and G. Otero, Analisis Cuantitativo del EEG en niños Retrasados Mentales Ligeros, in Estudios Avanzados en Neurociencias, Habana Cuba:, 1987, p [24] R. Biscay-Lirio, A. Alvarez, L. Galan-Garcia, J. C. Jimenez-Sobrino, R. Pascual-Marqui, and P. A. Valdes-Sosa, Selecting Box-Cox Transformations for Neurometric Data, in Estudios Avanzados en Neurociencias, 1987, p [25] S. Damiani, A. Alvarez Amador, J. Ricardo, R. D. Pacual Marqui, and P. A. Valdés Sosa, Analisis multivariado del electroencefalograma en escolares cubanos de 7 a 11 años; Multivariate analysis of electroencephalography in cuban students of 7 to 11 years, Estudios Avanzados en Neurociencias, [[26] J. Jimenez, A. M. Riveron Rojas, and P. A. Valdés-Sosa, Modelo Parametrico para el analisis de potenciales relacionados a eventos multiples, in Estudios Avanzados en Neurociencias, 1987, pp [27] R. D. Pascual, P. A. Valdes, J. C. Jimenez, and S. Gonzalez-Andino, Current source density estimation: a new method, in Estudios Avanzados en Neurociencias, vol. Editorial, 1987.

13 13 [28] R. D. Pascual, P. A. Valdes, J. Ricardo, A. Alvarez, and S. Damiani, Analisis Multivariado del EEG en Escolares Cubanos de 7 a 11 años, in Estudios Avanzados en Neurociencias, 1987, p [29] E. R. John, T. Harmony, and P. A. Valdes-Sosa, The use of statistics in electrophysiology in Methods of Analysis of Brain Electrical and Magnetic Signal, vol. 1A, A. S. Gevins and A. Remond, Eds. Amsterdam: Elsevier, 1987, pp [31] P. Valdes, Statistical Bases, in Neurometric Assessment of brain dysfunction in Neurological patients, T. Harmony, Ed. Hillsdale, New Jersey: Lawrence Erlbaum Associates, 1984, pp Papers published in peer review journals H index of 33 in February 2013 [1] J. Bosch-Bayard, P. A. Valdes-Sosa, T. Fernandez, G. Otero, B. Pliego Rivero, J. Ricardo- Garcell, B. Gonzalez-Frankenberger, L. Galan-Garcia, A. Fernandez-Bouzas, E. Aubert-Vazquez, A. Lage-Castellanos, R. Rodriguez-Valdes, and T. Harmony, 3D Statistical Parametric Mapping of quiet sleep EEG in the first year of life, NeuroImage, vol. 59, pp , Nov [2] G. Hernández-González, M. Álvarez-Sánchez, J. Jordán-González, L. Valdés-Urrutia, L. Melie- García, and P. A. Valdés-Sosa, Prevalencia de hallazgos incidentales en las imagenes de Resonancia Magnetica: Proyecto Cubano de Mapeo Cerebral Humano, Revista CENIC Ciencias Biologicas, vol. 43, no. 3, [3] X. Lei, P. A. Valdes-Sosa, and D. Yao, EEG/fMRI fusion based on independent component analysis: Integration of data-driven and model-driven methods Journal of integrative neuroscience, vol. 11, no. 3, pp , Sep [4] C. Luo, Q. Li, Y. Xia, X. Lei, K. Xue, Z. Yao, Y. Lai, E. Martínez-Montes, W. Liao, D. Zhou, P. A. Valdes-Sosa, Q. Gong, and D. Yao, Resting state basal ganglia network in idiopathic generalized epilepsy., Human brain mapping, vol. 33, no. 6, pp , Jul [5] B. Marcheco-Teruel, M. Cobas-Ruiz, N. Cabrera-Cruz, A. Lantigua-Cruz, E. García-Castillo, R. Lardoeyt-Ferrer, Z. Robaina-Jiménez, E. Fuentes-Smith, F. Morales-Calatayud, M. T. Lemus- Valdés, M. Portuondo-Sao, L. Comas-Pérez, J. M. Pérez-Crispí, T. Díaz-De Villal Villa, E. Icart- Perera, A. Jordán-Hernández, A. Lage-Castellanos, S. Rabell-Piera, J. de J. Llibre-Rodríguez, P. Valdés-Sosa, and M. Valdés-Sosa, The Cuban Twin Registry: Initial Findings and Perspectives Twin Research and Human Genetics, vol. 1, no. 1, pp. 1 6, Dec [6] I. Pedroso, M. L. Bringas, A. Aguiar, L. Morales, M. Álvarez, P. A. Valdés, and L. Álvarez, Use of Cuban recombinant human erythropoietin in Parkinson s disease treatment, MEDICC review, vol. 14, no. 1, pp , 2012.

14 14 [7] P. A. Valdes-Sosa, Coping with Brain Disorders using Neurotechnology, Malays J Med Sci., vol. 19, no. 1, pp. 1 3, [8] M. L. Bringas, C. Suarez, C. Sanchez, L. M. Alvarez, P. Valdes, S. Salazar, D. Chongo, and M. Jahanshahi, Cognitive changes after stem cell transplantation in a patient with subcortical stroke, BMJ Case Reports, vol. 2011, p. bcr , Jul [9] G. Hernandez-Gonzalez, M. L. Bringas-Vega, L. Galán-García, J. Bosch-Bayard, L. Melie-Garcia, Y. Lorenzo-Ceballos, L. Valdes-Urrutia, M. Cobas-Ruiz, and P. A. Valdes-Sosa, Multimodal Quantitative Neuroimaging Databases and Methods: the Cuban Human Brain Mapping Project, Clinical EEG and Neuroscience, vol. 42, no. 3, pp. 1 11, [10] R. Pascual-Marqui, P-A- Valdes-Sosa, J. J. Riera Cortical current source connectivity by means of partial coherence fields, arxiv preprint arxiv:, [11] A. Roebroeck, A. K. Seth, and P. Valdes-Sosa, Causal Time Series Analysis of functional Magnetic Resonance Imaging Data, JMLR: Workshop and Conference Proceedings, vol. 12, pp , [12] P. A. Valdes-Sosa, A. Roebroeck, J. Daunizeau, and K. Friston, Effective connectivity: Influence, causality and biophysical modeling NeuroImage, vol. 58, no. 2, pp , Apr [13] J. Bosch-Bayard, J. Riera-Diaz, R. Biscay-Lirio,. K. F. Wong, A. Galka, O. Yamashita, N. Sadato, R. Kawashima, E. Aubert-Vazquez, R. Rodriguez- Rojas, P. Valdes-Sosa, F. Miwakeichi, T. Ozaki, R. Rodriguez-Rojas. Spatio-temporal correlations from fmri time series based on the NN-ARx model Journal of Integrative Neuroscience, vol. 09, no. 04, pp , [14] E. R. C. Bravo, Y. Iturria, J. C. Praderes, L. Melie, P. A. Valdés, T. Virues, C. Machado, and L. V Urrutia, Noninvasive multimodal neuroimaging for rasmussen encephalopathy surgery: simultaneous EEG-fMRI recording Clinical EEG and Neuroscience, vol. 41, no. 3, pp , [15] G. Sanabria-Diaz, L. Melie-García, Y. Iturria-Medina, Y. Alemán-Gómez, G. Hernández- González, L. Valdés-Urrutia, L. Galán, and P. Valdés-Sosa, Surface area and cortical thickness descriptors reveal different attributes of the structural human brain networks Neuroimage, vol. 50, no. 4, pp , [16] P. A. Valdés-Hernández, A. Ojeda-González, E. Martínez-Montes, A. Lage-Castellanos, T. Virués-Alba, L. Valdés-Urrutia, and P. A. Valdes-Sosa, White matter architecture rather than cortical surface area correlates with the EEG alpha rhythm NeuroImage, vol. 49, no. 3, pp , Feb [17] M. A. Bobes, Y. Fernandez, F. Lopera, Y. T. Quiroz, L. Galan, M. Vega, N. Trujillo, M. Valdes- Sosa, and P. Valdes-Sosa, ERP Generator Anomalies in Presymptomatic Carriers of the

15 15 Alzheimer s Disease E280A PS-1 Mutation, Human Brain Mapping, vol. 31, no. 2, pp , [18] E. R. Cuspineda, C. Machado, T. Virues, E. Martínez-Montes, A. Ojeda, P. A. Valdés, J. Bosch, and L. Valdes, Source Analysis of Alpha Rhythm Reactivity Clinical EEG and Neuroscience, vol. 40, no. 3, pp , [19] G. Nolte, L. Marzetti, and P. Valdes Sosa, Minimum Overlap Component Analysis (MOCA) of EEG/MEG data for more than two sources Journal of neuroscience methods, vol. 183, no. 1, pp. 72 6, Sep [20] K. Uludag, A. C. Evans, V. Della-Maggiore, S. Kochen, E. Amaro, O. Sierra, P. Valdes- Hernandez, V. Medina, and P. Valdes-Sosa, Latin American Brain Mapping Network (LABMAN) NeuroImage, vol. 47, no. 1, pp , Aug [21] P. A. Valdés-Hernández, N. von Ellenrieder, A. Ojeda-Gonzalez, S. Kochen, Y. Alemán- Gómez, C. Muravchik, and P. A. Valdés-Sosa, Approximate average head models for EEG source imaging Journal of neuroscience methods, vol. 185, no. 1, pp , Dec [22] P. A. Valdés-Sosa and A. Obrador-Fragoso, Stratified Active Screening : Where Neurotechnology Meets Public Health MEDICC review, vol. 11, no. 1, pp. 7 10, [23] P. A. Valdes-Sosa, J. M. Sanchez-Bornot, R. C. Sotero, Y. Iturria-Medina, Y. Aleman-Gomez, J. Bosch-Bayard, F. Carbonell, and T. Ozaki, Model driven EEG/fMRI fusion of brain oscillations Human brain mapping, vol. 30, no. 9, pp , Sep [24] P. A. Valdes-Sosa, M. Vega-Hernández, J. M. Sánchez-Bornot, E. Martínez-Montes, M. A. Bobes EEG source imaging with spatio-temporal tomographic nonnegative independent component analysis Human brain mapping, vol. 30, no. 6, pp , Jun [25] E. Martínez-Montes, E. R. Cuspineda-Bravo, W. El-Deredy, J. M. Sánchez-Bornot, A. Lage- Castellanos, and P. A. Valdés-Sosa, Exploring event-related brain dynamics with tests on complex valued time-frequency representations Statistics in medicine, vol. 27, no. 15, pp , Jul [26] E. Martínez-Montes, M. Vega-Hernández, J. M. Sánchez-Bornot, and P. A. Valdés-Sosa, Identifying complex brain networks using penalized regression methods Journal of biological physics, vol. 34, no. 3, pp , Aug [27] E. Martinez-Montes, J. Sánchez-Bornot, and P. Valdés-Sosa, Penalized PARAFAC analysis of spontaneous EEG recordings Statistica Sinica, vol. 18, pp , [28] J. M. Sánchez-Bornot, E. Martinez-Montes, M. Vega-Hernandez, A. Lage-Castellanos, and P. A. Valdes-Sosa, Uncovering sparse brain effective connectivity: a voxel-based approach using penalized regression Statistica Sinica, vol. 18, pp , 2008.

16 16 [29] M. Vega-Hernandez, E. Martinez-Montes, J. M. Sanchez-Bornot, A. Lage-Castellanos, and P. A. Valdes-Sosa, Penalized least squares methods for solving the EEG inverse problem Statistica Sinica, vol. 18, no. 4, pp , [30] T. Fernández, T. Harmony, A. Fernández-Bouzas, L. Díaz-Comas, R. A. Prado-Alcalá, P. Valdés-Sosa, G. Otero, J. Bosch, L. Galán, E. Santiago-Rodríguez, E. Aubert, and F. García- Martínez, Changes in EEG current sources induced by neurofeedback in learning disabled children. An exploratory study. Applied psychophysiology and biofeedback, vol. 32, no. 3 4, pp , Dec [31] C. Machado, J. Korein, E. Aubert, J. Bosch, M. A. Alvarez, R. Rodríguez, P. Valdes, L. Portela, M. Garcia, N. Perez, and others, Recognizing a mother s voice in the persistent vegetative state Clinical EEG and neuroscience, vol. 38, no. 3, pp , [32] T. Gruber, N. J. Trujillo-Barreto, C.M. M. Giabbiconi, P. A. Valdés-Sosa, and M. M. Müller, Brain electrical tomography (BET) analysis of induced gamma band responses during a simple object recognition task NeuroImage, vol. 29, no. 3, pp , Feb [33] M. M. Müller, S. Andersen, N. J. Trujillo, P. Valdés-Sosa, P. Malinowski, and S. A. Hillyard, Feature-selective attention enhances color signals in early visual areas of the human brain Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 38, pp , Sep [34] J. J. Riera, P. A. Valdés, K. Tanabe, R. Kawashima A theoretical formulation of the electrophysiological inverse problem on the sphere Physics in medicine and biology, vol. 51, no. 7, pp , Apr [35] P. J. Durka, A. Matysiak, E. Martínez Montes, P. Valdés Sosa, and K. J. Blinowska, Multichannel matching pursuit and EEG inverse solutions Journal of neuroscience methods, vol. 148, no. 1, pp , Oct [36] P. A. Valdés-Sosa, R. Kötter, K. J. Friston, Introduction: multimodal neuroimaging of brain connectivity Philosophical transactions of the Royal Society of London. Series B, Biological sciences, vol. 360, no. 1457, pp , May [37] P. A. Valdés-Sosa, J. M. Sánchez-Bornot, A. Lage-Castellanos, M. Vega-Hernández, J. Bosch-Bayard, L. Melie-García, and E. Canales-Rodríguez, Estimating brain functional connectivity with sparse multivariate autoregression Philosophical Transactions of the Royal Society B: Biological Sciences, vol. 360, no. 1457, pp , May [38] F. Carbonell, L. Galan, P. Valdes, K. Worsley, R. J. Biscay, L. Diaz-Comas, M. A. Bobes, and M. Parra, Random field-union intersection tests for EEG/MEG imaging NeuroImage, vol. 22, no. 1, pp , May 2004.

17 17 [39] A. Galka, O. Yamashita, T. Ozaki, R. Biscay, and P. Valdés-Sosa, A solution to the dynamical inverse problem of EEG generation using spatiotemporal Kalman filtering NeuroImage, vol. 23, no. 2, pp , Oct [40] C. Machado, E. Cuspineda, P. Valdes, T. Virues, F. Llopis, J. Bosch, E. Aubert, E. Hernandez, A. Pando, M. A. Alvarez, E. Barroso, L. Galan, and Y. Avila, Assessing acute middle cerebral artery ischemic stroke by quantitative electric tomography Clinical EEG and Neuroscience, vol. 35, no. 3, pp , [41] J. L. Marroquin, T. Harmony, V. Rodriguez, and P. Valdes, Exploratory EEG data analysis for psychophysiological experiments NeuroImage, vol. 21, no. 3, pp , Mar [42] E. Martinez-Montes, P. A. Valdés-Sosa, F. Miwakeichi, R. I. Goldman, and M. S. Cohen, Concurrent EEG / fmri analysis by multiway Partial Least Squares NeuroImage, vol. 22, no. 3, pp , Jul [43] F. Miwakeichi, E. Martínez-Montes, P. A. Valdés-Sosa, N. Nishiyama, H. Mizuhara, and Y. Yamaguchi, Decomposing EEG data into space-time-frequency components using Parallel Factor Analysis NeuroImage, vol. 22, no. 3, pp , Jul [44] N. J. Trujillo-Barreto, E. Aubert-Vázquez, and P. A. Valdés-Sosa, Bayesian model averaging in EEG/MEG imaging NeuroImage, vol. 21, no. 4, pp , Apr [45] P. A. Valdes-Sosa, Spatio-temporal autoregressive models defined over brain manifolds Neuroinformatics, vol. 2, no. 2, pp , Jan [46] O. Yamashita, A. Galka, T. Ozaki, R. Biscay, and P. Valdes-Sosa, Recursive penalized least squares solution for dynamical inverse problems of EEG generation Human brain mapping, vol. 21, no. 4, pp , Apr [47] T. Fernandez, W. Herrera, T. Harmony, L. Diaz-Comas, E. Santiago, L. Sanchez, J. Bosch, A. Fernandez-Bouzas, G. Otero, J. Ricardo-Garcell, C. Barraza, E. Aubert, L. Galan, and P. Valdes, EEG and behavioral changes following neurofeedback treatment in learning disabled children Clinical Electroencephalography, vol. 34, no. 3, pp , [48] L. Morales-Chacon, J. Bosch-Bayard, P. Valdes-Sosa, M. A. Ortega-Perez, M. Zaldivar, and A. Sanchez, Brain electromagnetic tomography distinguishes primary generalised discharges from secondary bilateral synchrony Revista de Neurologia, vol. 36, no. 5, pp , [49] O. Yamashita, T. Ozaki, A. Galka, R. Biscay-Lirio, P. A. Valdes-Sosa, T. Ozaki, R. Biscay, and P. A. Valdes-Sosa, Dynamic inverse problem of EEG and the practical computation procedure for the solution Human Brain Mapping [50] A. Fernández-Bouzas, T. Harmony, T. Fernández, E. Aubert, J. Ricardo-Garcell, P. Valdés, J. Bosch, G. Casián, and R. Sánchez-Conde, Sources of abnormal EEG activity in spontaneous intracerebral hemorrhage Clinical Electroencephalography, vol. 33, no. 2, pp , 2002.

18 18 [51] T. Koenig, L. Prichep, D. Lehmann, P. A. Valdes-Sosa, E. Braeker, H. Kleinlogel, and R. Isenhart, Millisecond by millisecond, year by year: normative EEG microstates and developmental stages NeuroImage, vol. 16, no. 1, pp. 41 8, May [52] J. Bosch-Bayard, P. Valdes-Sosa, T. Virues-Alba, E. Aubert-Vazquez, E. R. John, T. Harmony, J. Riera-Diaz, and N. Trujillo-Barreto, 3D statistical parametric mapping of EEG source spectra by means of variable resolution electromagnetic tomography (VARETA) Clinical Electroencephalography, vol. 32, no. 2, pp , Apr [53] E. R. John, L. S. Prichep, W. Kox, P. Valdes-Sosa, J. Bosch-Bayard, E. Aubert, M. Tom, F. DiMichele, and L. D. Gugino, Invariant reversible QEEG effects of anesthetics Consciousness and cognition, vol. 10, no. 2, pp , Jun [54] T. Koenig, F. Marti-Lopez, and P. A. Valdes-Sosa, Topographic time-frequency decomposition of the EEG NeuroImage, vol. 14, no. 2, pp , Aug [55] E. Martínez-Montes, N. J. Trujillo-Barreto, L. Melie-García, and P. A. Valdés-Sosa, Variable Resolution Electromagnetic Tomography : a new type of inverse solution based on Bayesian Formalism Neuroimage, vol. 13, no. 6, p. 195, [56] F. Miwakeichi, R. Ramirez-Padron, P. A. Valdes-Sosa, and T. Ozaki, A comparison of nonlinear non-parametric models for epilepsy data Computers in Biology and Medicine, vol. 31, no. 1, pp , [57] L. Morales-Chacon, J. Bosch-Bayard, P. Valdes, and M. Zaldivar, Cerebral electrical tomography in bilateral congenital peri-sylvan syndrome Revista de Neurologia, vol. 32, no. 4, pp , [58] N. J. Trujillo-Barreto, E. Martinez-Montes, L. Melie-Garcia, and P. Valdes-Sosa, A symmetrical Bayesian model for fmri and EEG/MEG neuroimage fusion Int. J. Bioelectromagn, vol. 3, no. 1, pp , [59] T. Fernandez, T. Harmony, J. Gersenowies, A. Fernandez-Bouzas, J. Silva, S. I. Valdes, J. Bosch, L. Galan, E. Aubert, and P. Valdes, Verbal working memory differences between children and adults: A source EEG analysis Journal of Cognitive Neuroscience, pp , [60] A. Fernández-Bouzas, T. Harmony, T. Fernández, J. Silva-Pereyra, P. Valdés, J. Bosch, E. Aubert, G. Casián, O. G. Otero, and J. Ricardo, Sources of Abnormal EEG Activity in Brain Infarctions Clinical Electroencephalography, vol. 31, no. 4, p. 165, [61] T. Harmony, T. Fernandez, A. Fernandez-Bouzas, J. Silva-Pereyra, J. Bosch, E. Aubert, P. Valdes, F. Barrios, and D. Rodriguez, Estudios Funcionales de Imagen (tomografia electrica cerebral y resonancia magnetica funcional) durante la realizacion de una tarea de calculo mental Neuropsychologia Latina, vol. 8, no. 2, pp , 2000.

19 19 [62] J. Riera, E. Aubert-Vazquez, P. A. Valdés-Sosa, R. Casanova, and O. Lins, Discrete Spline Electric-Magnetic Tomography (DSPECT) Based on Realistic Neuroanatomy, in Biomag 96: proceedings of the Tenth International Conference on Biomagnetism:, [63] J. Silva-Pereyra, E. Aubert, J. Bosch, A. Fernandez-Bouzas, T. Harmony, T. Fernandez, P. Valdes, A. Salazar, and M. Rivera-Gaxiola, Source localization of strategies: N400 during lexical decision tasks Journal of Cognitive Neuroscience, p. 113, [64] A. Fernández-Bouzas, T. Harmony, J. Bosch, E. Aubert, T. Fernández, P. Valdés, J. Silva, E. Marosi, M. Martínez-López, and G. Casián, Sources of Abnormal EEG Activity in the Presence of Brain Lesions Clinical EEG electroencephalography, vol. 30, no. 2, pp , [65] W. A. Freiwald, P. Valdes, J. Bosch, R. Biscay, J. C. Jimenez, L. M. Rodriguez, V. Rodriguez, A. K. Kreiter, and W. Singer, Testing non-linearity and directedness of interactions between neural groups in the macaque inferotemporal cortex Journal of Neuroscience Methods, vol. 94, no. 1, pp , Dec [66] T. Harmony, T. Fernández, J. Silva, J. Bosch, P. Valdés, A. Fernández-Bouzas, L. Galán, E. Aubert, and D. Rodríguez, Do specific EEG frequencies indicate different processes during mental calculation? Neuroscience letters, vol. 266, no. 1, pp. 25 8, Apr [67] T. Ozaki, P. Valdes, and V. Haggan-Ozaki, Reconstructing the Nonlinear Dynamics of Epilepsy Data Using Nonlinear Time Series Analysis Journal of Signal Processing, vol. 3, no. 3, pp , [68] T. W. W. Picton, C. Alain, D. L. L. Woods, M. S. S. John, M. Scherg, P. Valdes-Sosa, J. Bosch-Bayard, and N. J. Trujillo, Intracerebral Sources of Human Auditory-Evoked Potentials, Audiol Neurootol, vol. 4, no. 416, pp , [69] P. A. Valdes, J. C. Jimenez, J. J. Riera, R. J. Biscay, and T. Ozaki, Nolinear EEG analysis based on a neural mass model Biological Cybernetics, vol. 81, no. 5 6, pp , Nov [70] G. F. Diáz, T. Virués, M. San Martiń, M. Ruiz, L. Galán, L. Paz, and P. Valdes, Generalized background qeeg abnormalities in localized symptomatic epilepsy Electroencephalography and clinical neurophysiology, vol. 106, no. 6, pp , Jun [71] J. C. Jimenez, P. A. Valdes-Sosa, L. M. Rodriguez, J. J. Riera, and R. Biscay, Computing the Noise Covariance Matrix of the Local Linearization Scheme for Numerical Solution of Stochastic Differential Equations Applied Mathematics Letters, vol. 11, no. 1, pp , [72] D. J. A. Moulden, T. W. Picton, N. Meiran, D. T. Stuss, J. J. Riera, and P. Valdes-Sosa, Event-related potentials when switching attention between task-sets, Brain and Cognition, vol. 37, no. 1, pp , [73] M. M. Muller, T. W. Picton, P. Valdes-Sosa, J. Riera, W. A. Teder-Salejarvi, S. A. Hillyard, M., Effects of spatial selective attention on the steady-state visual evoked potential in the Hz range Cognitive Brain Research, vol. 6, no. 4, pp , Apr

20 20 [74] J. J. Riera, M. E. Fuentes, P. A. Valdes, and Y. Oharriz, EEG-distributed inverse solutions for a spherical head model, Inverse Problems, vol. 14, no. 4, pp , [75] A. Fernandez-Bouzas, R. Casanova, T. Harmony, P. Valdes, E. Aubert, J. Silva, T. Fernandez, M. Martinez-Lopez, F. Garcia, and J. Bosch, EEG frequency domain distributed inverse solutions in brain lesions Electroencephalography and Clinical Neurophysiology, vol. 103, no. 1, p. 195, Jul [76] R. Biscay, J. Jimenez, J. Riera, and P. Valdes, Local linearization method for the numerical solution of stochastic differential equations Annals of the Institute of Statistical Mathematics, vol. 48, no. 4, pp , [77] J. L. Hernández, P. A. Valdés, and P. Vila, EEG spike and wave modeled by a stochastic limit cycle Neuroreport, vol. 7, no. 13, pp , Sep [78] M. M. Müller, J. Bosch, T. Elbert, A. Kreiter, M. V Sosa, P. Valdes Sosa, and B. Rockstroh, Visually induced gamma-band responses in human electroencephalographic activity a link to animal studies Experimental Brain Research, vol. 112, no. 1, pp , [79] R. Biscay, M. Lavielle, A. González, I. Clark, and P. Valdés, Maximum a posteriori estimation of change points in the EEG International journal of bio-medical computing, vol. 38, no. 2, pp , Feb [80] T. Harmony, A. Fernández-Bouzas, E. Marosi, T. Fernández, P. Valdés, J. Bosch, J. Riera, J. Bernal, M. Rodríguez, and A. Reyes, Frequency source analysis in patients with brain lesions Brain topography, vol. 8, no. 2, pp , Jan [81] J. L. Hernandez, J. L. Valdes, R. Biscay, J. C. Jimenez, and P. Valdes, EEG predictability: adequacy of non-linear forecasting methods International journal of bio-medical computing, vol. 38, no. 3, pp , Mar [82] J. L. Hernández, R. Biscay, J. C. Jimenez, P. Valdes, and R. Grave de Peralta, Measuring the dissimilarity between EEG recordings through a non-linear dynamical system approach International journal of bio-medical computing, vol. 38, no. 2, pp , Feb [83] J. J. Riera-Diaz, J. A. Carballo-Gonzalez, R. Biscay-Lirio, and P. A. Valdes-Sosa, The estimation of event related potentials affected by random shifts and scaling International journal of bio-medical computing, vol. 38, no. 2, pp , Feb [84] L. Galán, R. Biscay, P. Valdés, L. Neira, and T. Virues, Multivariate statistical brain electromagnetic mapping Brain topography, vol. 7, no. 1, pp , Jan [85] J. L. Hernández, P. Valdés, R. Biscay, T. Virues, S. Szava, J. Bosch, A. Riquenes, and I. Clark, A global scale factor in brain topography The International journal of neuroscience, vol. 76, no. 3 4, pp , Jun [86] S. Szava, P. Valdés, R. Biscay, L. Galan, J. Bosch, I. Clark, and J.C Jimenez, High Resolution Quantitative EEG Analysis Brain Topography, vol. 6, no. 3, pp , 1994.

21 21 [87] C. Machado, O. Garcia, J. Garcia-Tigera, P. A. Valdés-Sosa, P. Coutin, M. A. Buergo, J. Miranda, and J. Roman, Short Latency somatosensory evoked potentials in brain-dead patients using restricted low pass filter setting J Neurosurg Sci, vol. 37, no. 3, pp , [88] R. Biscay Lirio, L. Galán García, P. Valdés Sosa, T. Virues Alba, L. Neira Blaquier, and J. Rojas Vigoa,?Localization error in biomedical imaging Radiology, vol. 22, no. 4, pp , Jul [89] J. A. Carballo-Gonzalez, J. J. Riera-Diaz, R. Biscay-Lirio, and P. A. Valdes-Sosa, Model parameters estimation when the evoked potential recordings are affected by a random scale factor International journal of bio-medical computing, vol. 30, pp , Mar [90] P. Valdes, J. Bosch, R. Grave, J. Hernandez, J. Riera, R. Pascual, R. Biscay Frequency domain models of the EEG Brain Topography, vol. 4, no. 4, pp , [91] P. Valdés, M. Valdés, J. A. Carballo, A. Alvarez, G. F. Díaz, R. Biscay, M. C. Pêrez, S. Szava, T. Virués, M. E. Quesada QEEG in a Public Health System Brain Topography, vol. 4, no. 4, p. 259, Jan [92] C. Machado, P. Valdés, J. García-Tigera, T. Virues, R. Biscay, J. Miranda, P. Coutin, J. Román, O. García Brain-stem auditory evoked potentials and brain death Electroencephalography and clinical Neurophysiology, vol. 80, no. 5, pp , [93] R. Biscay, P. Valdes, and R. Pascual, Modified Fisher s linear discriminant functions with reduction of dimensionality J. Statist Comput. Simul., vol. 36, pp. 1 8, [94] S. L. Gonzalez Andino, R. D. Pascual Marqui, P. A. Valdes Sosa, R. Biscay Lirio, C. Machado, P. Figueredo Rodriguez, and C. Castro Torrez, Brain electrical field measurements unaffected by linked earlobes reference Electroencephalography and Clinical Neurophysiology, vol. 75, no. 3, pp , Mar [95] A. Alvarez Amador, P. A. Valdes-Sosa, R. D. Pascual-Marqui, L. Galan-Garcia, R. Biscay- Lirio, and J. Bosch-Bayard, On the structure of EEG development Electroencephalography and Clinical Neurophysiology, vol. 73, no. 1, pp , [96] R. Biscay, P. A. Valdés Sosa, J. C. Jiménez-Sobrino, and L. Galán Garcia, Multivariate Box- Cox transformations with applications to neurometric data Computers in Biology and Medicine, vol. 19, no. 4, pp , [97] J. A. Carballo-Gonzalez, P. Valdes-Sosa, and M. Valdes-Sosa, Detection of event related potentials Intern. J. Neuroscience, vol. 35, no. 3 4, pp , [98] E. Aubert-Vazquez, R. D. Pascual-Marqui, P. A. Valdes-Sosa, J. Antelo, and S. Gonzalez, Graficacion de imagenes biomedicas cerebrales en microcomputadora Revista CENIC Ciencias Biologicas, vol. 19, no. 3, pp , 1988.

22 22 [99] T. Harmony, A. Alvarez, R. Pascual, A. Ramos, E. Marosi, A. E. Díaz de León, P. Valdés, and J. Becker, EEG maturation on children with different economic and psychosocial characteristics The International journal of neuroscience, vol. 41, no. 1 2, pp , Jul [100] R. D. Pascual-Marqui, P. A. Valdes-Sosa, and A. Alvarez-amador, A parametric model for multichannel EEG spectra The International journal of neuroscience, vol. 40, no. 1 2, pp , May [101] R. D. Pascual-Marqui, S. L. Gonzalez-Andino, P. A. Valdés-Sosa, and R. Biscay-Lirio, Current source density estimation and interpolation based on the spherical harmonic fourier expansion International Journal of Neuroscience, vol. 43, no. 3 & 4, p. 237, [102] A. Alvarez, P. Valdes, and R. Pascual, EEG developmental equations confirmed for Cuban schoolchildren Electroencephalography and clinical neurophysiology, vol. 67, no. 4, pp , Oct [103] M. J. Valdes-Sosa, M. A. Bobes, M. C. Perez-Abalo, M. Perera, J. A. Carballo, and P. Valdes- Sosa, Comparison of Auditory-Evoked Potential Detection Methods Using Signal Detection Theory International Journal of Audiology, vol. 26, no. 3, pp , Jan [104] A. M. Riveron, J. Antelo, R. Pascual-Marqui, P. A. Valdes-Sosa, O. Baez, and E. Fermin, Evaluador de Imagenes para la Tomografia Computarizada basado en una microcomputadora. Algoritmos de Procesamiento en la logica de FUZZY, Revista CENIC Ciencias Biologicas, vol. 17, no. 3, pp , [105] S. Damiani, A. Alvarez, P. Valdes, O. Baez, R. Pascual, and J. Ricardo, Medidas neurometricas univariadas en escolares cubanos de 7 a 11 años, Revista de Ciencias Biologicas, vol. 16, no. 1, pp , [106] T. Harmony, G. Fernandez, P. Valdes, and A. Alvarez, A Neurometric Approach to Discrimination Between Different Types of Brain-Lesions, Electroencephalography and Clinical Neurophysiology, vol. 49, no. 1 2, p. 47, [107] P. A. Valdes-Sosa and L. Romero, Un Metodo para docimar la Multinormalidad Compleja, Control Cibernetica y Automatizacion, vol. 3, p. 43, [108] E. R. John, B. Z. Karmel, W. C. Corning, P. Easton, D. Brown, H. Ahn, M. John, T. Harmony, L. Prichep, A. Toro, I. Gerson, F. Bartlett, R. Thatcher, H. Kaye, P. Valdes, and E. Schwartz, Neurometrics Science, vol. 196, no. 4297, pp , [109] P. Valdes-Sosa, T. Harmony, and J. Ricardo, Clasificacion de los potenciales evocados, Revista CNIC, [110] T. Harmony, J. Ricardo-Garcell, G. Otero, G. Fernandez, S. Llorente, and P. Valdes, Symmetry of the visual evoked potential in normal subjects, Electroencephalogr Clin Neurophysiol, vol. 35, pp , Sep

23 Scientific Meetings Proceedings P. Valdes-Sosa, M. L. Bringas-Vega, J. Bosch-Bayard, J. M. Sanchez-Bornot, T. Koenig, and T. Harmony, Resting state EEG connectivity by frequency domain tomographic ICA, International Journal of Psychophysiology, vol. 85, no. 3, pp , P. A. Valdés-Sosa, EEG source signatures of learning disability subtypes uncovered by smooth-lasso discriminant analysis, International Journal of Psychophysiology, vol. 85, no. 3, p. 327, P. A. Valdes-Sosa, J. Bosch-Bayard, T. Fernandez, G. Otero, B. P. Rivero, J. Ricardo-Garcell, B. González-Frankenberger, L. Galán-García, A. Lage-Castellanos, and A. Fernandez- Bouzas, 3D Statistical Parametric Mapping of quiet sleep EEG in the first year of life, in Neuroinformatics, L. Melie-Garcia, C. Sánchez-Catasús, G. Sanabria-Diaz, and P. A. Valdes-Sosa Studying the Topological Organization of the human networks using Cerebral Blood Flow measurements in OHBM, M. Borrego, N. Trujillo-Barreto, Y. Rodríguez-Puentes, J. Bosch-Bayard, E. Martínez-Montes, L. Melie-García, E. Aubert, and P. Valdés-Sosa, Neuronic Localizador de Fuentes : Sistema para el Calculo de la Tomografia Electrica/Magnetica Cerebral, in V Latin American Congress on Biomedical Engineering CLAIB 2011 May 16-21, 2011, Habana, Cuba, 2011, pp G. Sanabria-Diaz, L. Melie-García, Y. Iturria-Medina, Y. Alemán-Gómez, G. Hernández- González, L. Valdés-Urrutia, L. Galán, and P. Valdés-Sosa, Studying structural human brain networks using cortical surface area as morphometric descriptor, in OHBM, 2010, vol. 50, no. 4, pp M. J. Sturzbecher, A. Lage, T. R. Velasco, R. M. F. Fernandes, A. C. Sakamoto, P. A. Valdes- Sosa, and D. B. de Araujo Localizing interictal epileptiform discharges using Kullback-Leibler distance by simultaneous Electroencephalography and functional magnetic resonance imaging acquisition Neuroimage, vol. 47, p. S114, M. Vega-Hernández, E. Martínez-Montes, J. Pérez-Hidalgo-Gato, J. M. Sánchez-Bornot, and P. Valdés-Sosa, Penalized Regression Methods in the Source Analysis of Face Recognition in Advances in Cognitive Neurodynamics ICCN 2007, 2008, pp E. Martínez-Montes, R. Sarmiento-Pérez, J. M. Sánchez-Bornot, and P. A. Valdés-Sosa, Information Entropy-Based Penalty for PARAFAC Analysis of Resting EEG, Advances in Cognitive Neurodynamics ICCN 2007, pp , 2008.

24 J. Bosch Bayard, J. Riera Díaz, R. Biscay Lirio, K. Wong, O. Yamashita, P. A. Valdés Sosa, and T. Ozaki, Spatio-temporal correlations in fmri time series: The innovation approach, Clinical Neurophysiology, vol. 119, no. 9, pp. e137 e138, Sep Calzada, A. Alvarez, A. Lage, Y. Alemán, L. Melie, and P. Valdes, Brain volume asymmetries in normal subject, Clinical Neurophysiology, vol. 119, p. S160, G. H. González, M. L. Bringas Vega, Y. L. Ceballos, J. M. Bornot, and P. A. Valdés-Sosa, Brain bases of psychometric intelligence: WAIS III and brain volume, Clinical Neurophysiology, vol. 119, p. S163, G. Hernández González, ML Bringas Vega, Y. Lorenzo Ceballos, J. M. Sánchez Bornot, Y. Alemán, P. A. Valdés-Sosa, A. Lage Castellanos, and A. Ojeda, Cortical thickness and intelligence in normal adult subjects, Clinical Neurophysiology, vol. 119, no. 2008, p. P01.19, R. Rodríguez Rojas, M. Vega Hernández, J. M. Sánchez Bornot, M. Carballo Barreda, J. Bosh, E. Aubert, and P. Valdés Sosa, Sparse connectivity in the motor circuit of basal ganglia: A multivariate autoregressive analysis, Clinical Neurophysiology, vol. 119, no. 9, pp. e139 e139, E. R. Cuspineda, T. Virués, E. Martínez, A. Ojeda, J. Bosch, and P. A. Valdés, Source analysis of alpha rhythm reactivity using individual MRI, Clinical Neurophysiology, vol. 119, no. 9, pp. e149 e149, G. H. González, M. L. Bringas Vega, P. A. Valdés-Sosa, A. Ojeda, and A. L. Castellanos, Relationship between psychometric intelligence and white matter integrity obtained from DTI study in normal subjects, Clinical Neurophysiology, vol. 119, p. S163, P. A. Valdés-Sosa, Cuban Human Brain Mapping (HBM) project, Clinical Neurophysiology, vol. 119, p. S143, G. H. González, M. L. Bringas Vega, P. A. Valdés-Sosa, A. L. Castellanos, and A. Ojeda, Reaction time and fractional anisotropy, Clinical Neurophysiology, vol. 119, p. S162, E. Martínez Montes, J. M. Sánchez Bornot, and P. A. Valdés Sosa, Penalized parafac analysis of resting-state EEG, Clinical Neurophysiology, vol. 119, no. 9, pp. e138 e139, Sep A. Ojeda González, P. Valdés Hernández, P. A. Valdés Sosa, and V. Sosa, EEG spectra correlates with diffusion tensor fractional anisotropy, Clinical Neurophysiology, vol. 119, no. 9, pp. e130 e130, Sep P. A. Valdés-Sosa, Measuring activation and causality from functional neuroimages using multiple prior information, Clinical Neurophysiology, vol. 119, p. S150, 2008.

25 P. A. Valdés Hernández, N. Von Ellenrieder, A. Ojeda González, C. Muravchik, S. Kochen, and P. A. Valdés Sosa, Solving EEG forward and inverse problem for subject lacking of a MRI, Clinical Neurophysiology, vol. 119, no. 9, pp. e115 e116, Sep F. Miwakeichi, P. Valdes-Sosa, E. Aubert-Vazquez, J. Bayard, J. Watanabe, H. Mizuhara, and Y. Yamaguchi, Decomposing EEG Data into Space-Time-Frequency Components Using Parallel Factor Analysis and Its Relation with Cerebral Blood Flow, Neural Information Processing, pp , M. Vega-Hernandez, E. Martinez-Montes, J. M. Sanchez-Bornot, A. Lage-Castellanos, and P. Valdes-Sosa, Metodos de regresion con penalizadores no convexos en la solucion del problema inverso del EEG, in BioInformatica2007 (CD) BIO030). ISBN: , R. Rodriguez-Rojas, M. Vega-Hernandez, A. Lage, J. Sanchez, M. Carballo, J. Bosh, and P. Valdes-Sosa, Exploring sparse connectivity in the motor system using multivariate autoregression analysis, BMC Neuroscience, vol. 8, pp. 1 2, M. Vega-Hernandez, E. Martinez-Montes, J. M. Sanchez-Bornot, and P. A. Valdes-Sosa, Penalized regression methods in the source analysis of face recognition, in Proceedings of the 1st International Conference on Cognitive Neurodynamics, Nov.17-21, 2007,, E. Martinez-Montes, J. M. Sanchez-Bornot, and P. Valdes-Sosa, Generalized Penalized PARAFAC analysis of EEG time series, vol. 36, no. S1 CD, June 10 14, M. L. Bringas, M. Baez, J. F. Connolly, and P. A. Valdes-Sosa, Analyzing the effect of semantic incongruences on event related brain dynamics, International Journal of Psychophysiology, vol. 61, no. 3, p. 331, M. L. Bringas-Vega, M. M. Baez-Martin, J. F. Connolly, and P. A. Valdes Multivariate and non parametric detection of event-related brain dynamics, Psychophysiology, vol. 43, pp. S27 S27, F. Miwakeichi. P. A. Valdes-Sosa, H. Mizuhara, N. Nishiyama, and Y. Yamaguchi, Parallel Factor Analysis can extract significant activities in multi channel EEG, in OHBM, F. Miwakeichi, P. A. Valdes-Sosa, H. Mizuhara, L. Wang, and K. Kobayashi, How nonlinear is the hemodyanmic response?: analysis of EEG / fmri with semiparametric autoregression Modeling & Analysis, in OHBM, 2005, pp F. Miwakeichi, P. Valdes-Sosa, J. Bosch-Bayard, E. Aubert-Vazquez, and H. Mizuhara, Estimation of Hemodynamic Response Function using Partially Linear Models in concurrent EEG/fMRI data Presented at the 11th Annual Meeting of the Organization for Human Brain Mapping Toronto, Ontario, Canada. Available on CD-Rom in NeuroImage, 2005, vol. 26, no P. A. Valdés-Sosa and J. B. Bayard, Nonlinear Measures of Influence between EEG Sources Presented at the 11th Annual Meeting of the Organization for Human Brain Mapping,

26 26 June 12-16, 2005, Toronto,Ontario, Canada.Available on CD-Rom in NeuroImage, 2005, vol A. Janke, J. M. Sánchez-Bornot, S. Rose, S. Finnigan, E. R. Cuspineda-Bravo, E. Aubert- Vázquez, P. A. Valdés-Sosa, and J. Chalk, Tomographic quantitative EEG mapping in acute stroke, in The Stroke Society of Australasia (SSA) 2004 Annual Scientific Meeting (ASM), 2005, vol. 35, no. 2, pp. A4 A E. R. Cuspineda-Bravo, J. M. Sánchez-Bornot, P. A. Valdés-Sosa, E. Aubert-Vázquez, S. Finnigan, J. Chalk, S. Rose, and A. Janke, Hyperacute stroke evolution mapped by individualized tomographic qeeg, in HBM 04: 10th Annual Meeting of the Organization for Human Brain Mapping (OHBM), 2004, vol. 22, no. Supp. 1, pp. e2525 e A. Gonzalez, J. L. Marroquin, S. Botello, F. Calderon, P. Valdes, E. Aubert, J. Bosch, A. Fernandez-Bouzas, and T. Harmony, Registration of brain MRI of patients with a tumor, in Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439), 2004, vol. 1, no. 1, pp R. C. Sotero, P. Valdes-Sosa, and M. C. Perez, Analisis Mediante Un Modelo Biofisico De La Respuesta Temporal De La Coclea Provocada Por Multiples Tonos Simultaneos Modulados En Amplitud in Revista CENIC Ciencias Biologicas, vol. 35, no. 3, (Suplemento), p. 378, L. Melie-Garcia, N. Trujillo-Barreto, E. Martinez, T. Koenig, P. Valdes-Sosa, and K. J. Friston, EEG imaging via BMA with FMRI pre-defined prior model probabilities in NeuroImage, 2004, vol. 22, no. CD, p. We 245 We J. M. Sanchez-Bornot, P. A. Valdes-Sosa, and E. Cuspineda, Eliminacion de artefactos del EEG con ICA en infartos cerebrales Revista CENIC Ciencias Biologicas, vol. 35, no. 4, p. 270, N. Trujillo-Barreto, L. Melie-Garcia, E. Cuspineda, E. Martinez, and P. A. Valdes-Sosa, Bayesian Inference and Model Averaging in EEG/MEG imaging in NeuroImage, 2003, vol. 19 (2)Supp. 41. P. Valdes-Sosa, EEG/MEG tomography and beyond: multimodality image fusion in Restorative neurology and neuroscience, vol. 21, no. 5. p. 236, R. Goldman, E. Martinez-Montes, P. Valdes-Sosa, and M. S. Cohen, Convergent evidence for distributed sources of alpha rhythm, in Journal of Neuroscience, 2003, UCLA Brain Mapping Center 43. F. Miwakeichi, E. Martinez, P. A. Valdes-Sosa, H. Mizuhara, N. Nishiyama, and Y. Yamaguchi, Parallel Factor Analysis can extract significant activities in multi-channel EEG, in NeuroImage, no. supp junio, V. Rodriguez, J. L. L. Marroquin, T. Harmony, and P. Valdes, Exploratory EEG data analysis for neurophysiological experiments, in Proceedings of the 25th Annual International

27 27 Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439), 2003, vol. 1, pp L. Morales-Chacón, J. Bosch-Bayard, P. Valdés-Sosa, M. A. Ortega-Pérez, M. Zaldívar, and A. Sánchez, Tomografia eléctrica cerebral para distinguir las descargas generalizadas primarias de la sincronía bilateral secundaria, in Revista de neurología, vol. 36, no. 5, pp , A. Galka, 山 下 宙 大, 尾 崎 統, R. Biscay, and P. Valdes-Sosa, Spatiotemporal Kalman Filtering as a Tool for Solving the Inverse Problem of EEG Generation in Summary of the Reports at the 71th Annual Meeting 日 本 統 計 学 会 誌, vol. 33, no. 3, p. 416, GALKA, 山 下 宙 大, 尾 崎 統, R. BISCAY, and P. A. Valdes-Sosa, Spatiotemporal Kalman filtering: A new approach for solving high-dimensional inverse problems, in 日 本 統 計 学 会 講 演 報 告 集, vol. 71, pp , F. Carbonell, L. Galan, R. J. Biscay, P. Valdes, L. Diaz-Comas, K. Worsley, and M. A. Bobes, Detection of event related potential components based on the distribution of the maximun of a T2 random process, NeuroImage, vol. 13, no. 6, p. S90, N. J. Trujillo-Barreto, E. Martínez-Montes, P. A. Valdés-Sosa, L. Melie-García Bayesian Model for EEG/MEG and fmri data Fusion, in Neuroimage, 2001, vol. 13, no. 6, p Machado, P. Valdes, T. Virues, J. Bosch, E. Aubert, E. Barroso, M. A. Alvarez, and A. Pando, Quantitative electroencephalographic tomography for assessing acute stroke, in Annals of Neurology, vol. 50, no. 3, pp. S42 S42, M. A. Bobes, F. Lopera, M. Garcia, L. D. Comas, P. Valdes-Sosa, and M. Valdes-Sosa, Activation of brain areas related to face processing in prosopagnosia, in NeuroImage, vol. 13, no. 6, pp. S1027 S1027, J. J. Riera, P. A. Valdés-Sosa, E. Aubert-Vázquez, A. Evans, and K. Worsley, An analysis of brain sources and connectivity patterns associated with alpha rhythm reactivation in human in NeuroImage, vol. 13, no. 6, p. 233, Jun F. Morales, D. Macdonald, P. Valdes Sosa, and A. Evans, Transferring the Montreal Neurological Institute Image Processing Tools to a Windows Platform, in NeuroImage, vol. 11, no. 5, p. S922, E. R. John, L. S. Prichep, R. Cancro, W. Herrmann, G. W. Winterer, and P. Valdes-Sosa, QEEG subtyping of schizophrenics predicts response to medication, in Schizophrenia Research, vol. 41, no. 1, p. 142, L. S. Prichep, E. R. John, P. Valdes, J. Bosch, and F. di Michele, Evaluation of cognitive deterioration in elderly by a new neuroimaging tecnique: Low Resolution Electric Tomography (LORETA), in Zeitschrift Fur Gerontologie Und Geriatrie, vol. 32, no. 2, p. 124, 1999.

28 M. L. Bringas, P. Valdes-Sosa, B. Ramirez, J. L. Rodriguez, and M. Rodriguez-Mena, Eventrelated potentials reflect implicit memory in recognition of unfamiliar faces, in Brain and Cognition, vol. 40, no. 1, p. 15, P. A. Valdes-Sosa, N. Trujillo, J. Bosh, E. Aubert, and J. Riera, Constraining EEG-MEG Source Imaging with Statistical Neuroanatomy, in NeuroImage, J. Bosch, T. Virues, I. Clark, E. Aubert, N. Trujillo, F. Morales, C. Machado, and P. Valdes, Early Signs of Stroke detected by SPM of EEG Source Spectra., in NeuroImage, vol. 7, no. 4, p. 652, P. A. Valdes-Sosa, Nonlinear Measures of Influence between EEG Sources, in Neuroimage, vol. 7, P. A. Valdes, J. Bosch, T. Virues, E. Aubert, E. Fermin, E. Gonzalez, and P. A. Valdés-Sosa, EEG source frequency domain SPM, in NeuroImage, vol. 7, no. 4, p. 636, L. S. Prichep, E. R. John, P. A. Valdes-Sosa, and F. Michele di, QEEG-LORETA Statistical Images of Cognitive Deterioration in the Elderly in NeuroImage, vol. 7, no. 4, pp. S518 S518, N. Trujillo, P. Valdes, and J. Bosch, Fast Transform methods for regularized EEG-MEG Inverse Solutions in NeuroImage, vol. 7, no. 4, pp. S637 S637, A. Fernandez-Bouzas, T. Harmony, J. Bosch, E. Aubert, T. Fernandez, P. Valdes, J. Ç. Silva, and M. Marti-Lopez, EEG Source Spectra in Brain Infarcts in NeuroImage, vol. 7, no. 4, p. 660, J. Riera, P. A. Valdes-Sosa, and M. Fuentes, Explicit Backus and Gilbert EEG Inverse Solution lot-spherical Symmetry, in Biomedizinische Technik, pp. 1 2, P. Valdes, J. Bosch, F. Morales, I. Clark, F. Amador, and T. Virues, qeeg signs of HIV infection in Electroencefalography and Clinical Neurophysiology, vol. 103, no. 1. p. 28, E. R. John, L. S. Prichep, and P. Valdes-Sosa, Neurometric EEG classification and subtyping of psychiatric patients in Electroencephalography and Clinical Neurophysiology, vol. 103, no. 1, pp , Jul O. G. Lins, T. W. Picton, V. Choi, P. Valdes-Sosa, J. Riera, and R. Casanova, Scalprecorded electrical fields: From sensors to sources in International Journal of Psychophysiology, vol. 25, no. 1, pp , E. R. John, L. S. Prichep, and P. Valdes-Sosa, Approach to biological nosology, in Biological Psychiatry, vol. 42, no. 1supp1, p. 64S 64S, Jul J. Riera, M. E. Fuentes, P. A. Valdes, and Y. Oharriz, Theorical basis of the EEG. Head Model in Biomedizinische Technik, vol. 42, no. 1, pp , P. A. Valdes-Sosa, Quantitative electroencepholographic tomography, in EEG and Clinical Neurophysiology, 1997, vol. 103, no. 1, p. 19.

29 L. Gamez, L. Rodriguez, A. T. Virues, J. Bosch-Bayard, and P. A. Valdes-Sosa, Analisis Tomografico funcional de la actividad electrica cerebral en 2 pacientes con esclerosis multiple y epilepsia parcial sintomatica in Revista CENIC Ciencias Biologicas, vol. 28, no. 3, A. Alvarez, T. Virues-Alba, P. A. Valdes-Sosa, J. Bosch-Bayard, and F. Morales, Analisis Tomografico funcional de la actividad electrica cerebral en pacientes infectados por HIV. Estudio Longitudinal, Revista CENIC Ciencias Biologicas, vol. 28, no. 3, P. Valdes-Sosa, J. Bosch, T. Virues, and J. Riera, EEG Source Norms, in Brain Topography, vol. 5, no. 4, P. Valdes, J. L. Hernández, R. Biscay, R. Grave de Peralta, A. Gonzalez, J. L. Valdes, Nonlinear Quantitative EEG Analysis Electroencephalography and Clinical Neurophysiology, vol. 87, no. 2, p. S135, J. Riera, J. Carballo, R. Biscay, and P. Valdes, ERP component estimation, International Journal of Psychophysiology, vol. 11, no. 1, p. 69, S. L. Gonzalez-Andino, R. Grave de Peralta Menendez, J. C. Jimenez Sobrino, R. Pascual Marqui, R. Biscay Lirio, and P. A. Valdes Sosa, Realistic Head Geometry and ERP Generators, in International Journal of Psychophysiology, vol. 11, no. 1, p. 34, P. Valdes, R. Biscay, and R. Pascual, Seperable models for the EEG and ERP, in International Journal of Psychophysiology, vol. 11, no. 1, p. 83, Jul P. Valdés, R. Biscay, L. Galán, J. Bosch, S. Szava, and T. Virués, High resolution spectral EEG norms for topography, in Brain Topogr, vol. 3, pp , P. A. Valdes-Sosa, R. Biscay-Lirio, Lidice Galan, J. Bosch-Bayard, S. Szava, and T. Virues, High Resolution Spectral norms for Topography, in International Journal of Neuroscience, p. 281, T. Virués, R. Biscay, L. Galan, E. Aubert, J Rojas, J. Bosch, L. Neira, and P. Valdes-Sosa, Precision de la localizacion de lesiones mediante mapas neurometricos, in Revista CNIC, vol. 21, J. Miranda, O. Hernandez, M. Buergo, R. Santiesteban, P. Coutin, J. Pumariega, P. A. Valdes-Sosa, and J. Roman, Diagnostico Precoz de la muerte encefalica, in EEG and Clinical Neurophysiol, R. Biscay-Lirio, P. Valdes-Sosa, L. Diaz-Coma, V. Martin, J. C. Jimenez-Sobrino, and J. Antelo, Compacting the EEG Subband Coding in Int J Neurosci, vol. 49, p. 251, J. A. Carballo-Gonzalez, P. A. Valdes-Sosa, and R. Biscay-Lirio, Estimation of evoked potentials using a generalized version of wiener filter, in Int J Neurosci, vol. 49, p. 252, S. Gonzalez-Andino, R. Grave de Peralta, J. C. Jimenez-Sobrino, R. Biscay-Lirio, R. Pascual- Marqui, E. Aubert-Vazquez, P. Valdes-Sosa, and J. Gamez, A New Solution Method for the

30 30 Electroencephalographic Direct Problem in Realistic Geometry, in Int J Neurosci, vol. 49, p. 247, J. C. Jimenez, J. A. Carballo-Gonzalez, P.-A. MC, R. Biscay-Lirio, M. Valdes-Sosa, and P. Valdes-Sosa, Discrimination of Normal Abnormal and no response Auditory Brainstem Records: A Comparison Between Quantitative Measures and Human Observation in Int J Neurosci, vol. 49, p. 247, E. Aubert-Vazquez, E. Alfonso, R. Pascual-Marqui, P. A. Valdes-Sosa, J. Antelo, and S. Gonzalez-Andino, Functional and Anatomical Brain Imaging Work Station on a Personal Computer in Intern. J.Neuroscience, vol. 49, p. 253, L. Galan-Garcia, P. Valdes-Sosa, S. Szava, R. Biscay-Lirio, and J. Bosch-Bayard, Solution for some Statistical Problems of EEG Norming, in Int J Neurosci, vol. 49, p. 244, S. Szava, P. A. Valdes-Sosa, L. Galan-Garcia, J. Bosch-Bayard, R. Biscay-Lirio, M. E. Quesada, A. A. Alvarez, C. Rodriguez, P. Figueredo-Rodriguez, T. Virues-Alba, P.-A. MC, E. Guma, and G. Diaz, Quantitative EEG norms for the Cuban Population between the ages of 5 and 97 years in Intern. J. Neuroscience, vol. 49, p. 246, J. Antelo, L. Diaz-Coma, P. Valdes-Sosa, V. Martin, J. C. Jimenez-Sobrino, and R. Biscay- Lirio, Codificacion por Subbandas del EEG, in Revista CENIC Ciencias Biologicas, vol. 19, no. 3, p. 119, S. Gonzalez-Andino, E. Aubert-Vazquez, R. Biscay-Lirio, P. A. Valdes-Sosa, R. Pascual- Marqui, and R. Grave de Peralta, Efecto de la Geometria No-Esferica en los Problemas Directo e Inverso de la Actividad Electrica Cerebral, in Revista CENIC Ciencias Biologicas, vol. 19, p. 9, R. Biscay-Lirio, J. C. Jimenez-Sobrino, and P. Valdes, Numeric solution of integral equations using parametric approximation for the surfaces., in Revista CENIC Ciencias Biologicas, vol. 19, no. 3, p. 197, P. A. Valdes-Sosa, R. Pascual-Marqui, and S. Gonzalez-Andino, Modelacion Fisica de la Distribucion Espacial de los Procesos XI y ALFA del EEG, in Revista CENIC Ciencias Biologicas, vol. 19, p. 9, L. Galan-Garcia, S. Szava, A. Alvarez, P. A. Valdes-Sosa, and J. Bosch-Bayard, Ingenieria Estadistica para la Construccion y Evaluacion de Ecuaciones de Regresion del EEG, in Revista CENIC Ciencias Biologicas, vol. 19, p. 9, R. Biscay-Lirio, J. C. Jimenez, and P. A. Valdes-Sosa, Solucion numerica de ecuaciones integrales utilizando aproximaciones parametricas para las superficies in Revista CNIC Ciencias Biologicas, vol. 19, no. 3, pp , 1988.

31 J. C. Jimenez-Sobrino, P. A. Valdes-Sosa, R. Biscay-Lirio, M. C. Perez-Abalo, J. A. Carballo- Gonzalez, Comparacion de la Eficiencia Diagnostica de Medidas de Normalidad para Potenciales Evocados in Revista CENIC Ciencias Biologicas, vol. 19, no. 3, p. 139, R. Biscay-Lirio, P. A. Valdes-Sosa, E. Aubert-Vazquez, Analisis Morfometrico Aplicado a Imagenes Biomedicas in Revista CENIC Ciencias Biologicas, vol. 19, no. 3, p. 136, E. Aubert-Vazquez, P. A. Valdes-Sosa, S. Gonzalez-Andino, O. Baez, R. Pascual-Marqui, and E. Alfonso, Graficacion de Mapas Cerebrales (MC) en alta Resolucion, in Revista CENIC Ciencias Biologicas, vol. 19, p. 8, A. Alvarez, P. Valdes, R. D. Pascual-Marqui, and J. Ricardo, Quantitative electroencephalographic differences between mildly mentally retarded and normal children, in Int J Neurosci, R. Pascual-Marqui, R. Biscay-Lirio, P. A. Valdes-Sosa, and A. Alvarez-Amador, Neurophysiological Aspects and Clinical Evaluation of a Parametric Model for the EEG, in The Second World Congress of Neuroscience (IBRO), 1987, vol. S545, pp. S545 S A. M. Riveron, J. Antelo, O. Baez, R. Pascual-Marqui, P. A. Valdes-Sosa, A. Gonzalez, J. Rojas Vigoa, and J. Almira, Lizard graphics. Modulo Basico para las aplicaciones graficas en microcomputadoras. Diseño e implementacion., in Revista CENIC Ciencias Biologicas, vol. 17, no. 3, pp , J. Antelo, J. C. Jimenez-Sobrino, P. A. Valdes-Sosa, and J. Ricardo-Garcell, Evaluador de Imagenes para la Tomografia Computarizada Basado en una Microcomputadora Diseño e Implementacion, in Revista CENIC Ciencias Biologicas, vol. 17, no. 3, p. 141, Patents 1. Method and system for the evaluation and visual display of abnormal electromagnetic physiological activity of the brain and the heart. P. Valdés, R. Biscay, R. Pascual, L. Neira, L. Galán, J.C. Jiménez, J. Bosch. United States Patent US A. Feb., Method and system for three dimensional tomography of activity and connectivity of brain and heart electromagnetic waves generators. P. Valdés, J. Riera, J. Bosch, R. Biscay, S. González, R. Grave de Peralta, R. Pascual. United States Patent. US , May, Mapas estadísticos tridimensionales del estado funcional cerebral mediante la tomografía electro y/o magnética encefalográfica. P. Valdés, J. Riera, J. Bosch, F. Morales, E. Aubert, T. Virués. Oficina Cubana de la Propiedad Industrial. Sept., System and Method for a Tomography of the Primary Currents of the Brain and Heart. P. Valdés, J. Riera, J. Bosch, F. Morales, E. Aubert, T. Virués. Oficina Cubana de la Propiedad

32 32 Industrial. Nov. 98. CU PCT/CU1998/000006/ PCT WO99/10816.(In this moment is part of the state of technique). 5. New Naphthalene derivatives obtaining procedure for Alzheimer s disease in vivo diagnosis. Marquiza Sablon Carrazana, Chryslaine Rodriguez-Tanty, Alejandro Perera Pintado, Suchitil Rivera Marrero, Rafaela Perez Perera, Rosa Aria Lopez Barroso, Anais I. Prats Capote, Herman Velez Castro, Carlos Serafin Perez Martinez, Pedro Antonio Valdes Sosa. European Patent Organization EPO. Date of international presentation: 2010/04/17 (in Cuba patented as: Procedimiento de obtención de nuevos derivados de Naftaleno para el diagnóstico in vivo de la Enfermedad de Alzheimer. PCT/CU2010/000001) Technical Reports A Quantitative Description of Development of Neurometric Parameters. Alvarez A., Valdés P.A., Pascual R.D. Technical report NC-003, National Center for Scientific Research. Havana, Cuba Multivariate Spectral Modeling of the EEG: The Xi-Alpha Model. Pascual R.D.; Valdés P.A. and Alvarez A. Technical Report No. NC-001. Neuroscience Branch, National Research Center of Cuba, Havana, Clinical Evaluation of the Xi-Alpha model for the EEG. Comparison with broad band spectral features. Alvarez A., Ricardo J., Valdés P.A., Pascual R.D. Technical report NH-001, Havana, Cuba: National Center for Scientific Research ISM No. 705: Valdes P, Bosch J, Jimenez JC, Trujillo N, Biscay RJ, Morales F, Hernandez JL, Ozaki T, The Statistical Identification of Nonlinear Brain Dynamics: A progress report [11/13/1998] The Institute of Statistical Mathematics, Tokyo ISM No. 652: Valdes P, Jimenez JC, Riera JJ, Biscay RJ, Ozaki T, Nonlinear EEG Analysis based on a neural mass model Research Memo No. 652, The Institute of Statistical Mathematics, Tokyo. ftp://ftp.ism.ac.jp/pub/res-memo/rm652.ps.gz57: ISM No. 657 Ozaki, T., Valdés-Sosa, P. and Ozaki, V.H. (1997) Reconstructing Nonlinear dynamics from time series: with Application to Epilepsy Data Analysis, Manchester University/UMIST Technical Report, 1997/02 ISM No. 1025: Bosch J, Riera JJ, Biscay RJ, Wong KFK, Yamashita O, Galka A, Sadato N, Kawashima R, Valdes P, Miwakeichi F, Ozaki T, Spatio-temporal correlations in fmri time series: the whitening approach[9/2/2007] The Institute of Statistical Mathematics, Tokyo

33 33 ISM No. 868: Yamashita O, Ozaki T, Galka A, Biscay RJ, Valdes P, Dynamic inverse problem and the practical computation procedure for the solution. [2/04/2003] The Institute of Statistical Mathematics, Tokyo ISM No. 862: Galka A, Ozaki T, Yamashita O, Biscay RJ, Valdes P, A solution to the dynamical inverse problem of EEG generation using spatiotemporal Kalman filtering. [12/27/2002] The Institute of Statistical Mathematics, Tokyo