Improving Life Transforming Value. May 1 st, 2015
|
|
- Sheena Scott
- 8 years ago
- Views:
Transcription
1 Improving Life Transforming Value May 1 st, 2015
2 Forward Looking Statement This presentation contains forward-looking statements made pursuant to the safe harbor provisions of the U.S. Securities Litigation Reform Act of Forward-looking statements involve known and unknown risks and uncertainties that could cause the Company's actual results to differ materially from those in the forward-looking statements. Such risks and uncertainties include, among others, the availability of funds and resources to pursue R&D projects and clinical trials, the successful and timely completion of clinical studies, the risk that safety and efficacy data from any of our Phase 3 trials may not coincide with the data analyses from previously reported Phase 1 and/or Phase 2 clinical trials, the ability of the Company to efficiently commercialize one or more of its products or product candidates, the ability of the Company to take advantage of business opportunities in the pharmaceutical industry, uncertainties related to the regulatory process, the ability to protect our intellectual property, the potential of liability arising from shareholder lawsuits and general changes in economic conditions. Investors should consult the Company's quarterly and annual filings with the Canadian and U.S. securities commissions for additional information on risks and uncertainties relating to forward-looking statements. Investors are cautioned not to place undue reliance on these forward-looking statements. The Company does not undertake to update these forward-looking statements. We disclaim any obligation to update any such factors or to publicly announce the result of any revisions to any of the forward-looking statements contained herein to reflect future results, events or developments, unless required to do so by a governmental authority or by applicable law. 2
3 Highlights Commercial-stage promotion EstroGel : Leading non-patch transdermal estrogen therapy product commercialized by Ascend Therapeutics in the US Promotion by Aeterna Zentaris sales force in the US on a sales commissions basis Clinical-stage development Zoptarelin doxorubicin: potential therapy for endometrial cancer ZoptEC Phase 3 trial (under SPA with FDA); wholly-owned, product candidate Potential additional indications (ex: ovarian, prostate, breast cancer therapies) Macrilen : potential drug for evaluating Adult GHD Growth Confirmatory Phase 3 efficacy trial to be initiated before year-end Actively pursuing other in-licensing, acquisition & promotion/co-promotion opportunities Innovative technology platform supporting long-term growth ( cytotoxic peptide conjugates and cell signaling ) Leadership Proven leadership with expertise in delivering revenue and earnings growth 3
4 At a Glance Transitioning to a specialty biopharmaceutical company Heavily focused on establishing revenues, cash and profitability Resource optimization / burn reduction is a priority NASDAQ: AEZS, TSX: AEZ Cash on hand as of December 31, 2014: $35.2 million with no debt Completed public offering March 11, 2015: $34.5 million net proceeds 4
5 Focused On Value Transformation Expansion of Commercial Operations Initiated selling Ascend s EstroGel in U.S. ZoptEC Interim Analysis Strategic Shift to Commercial Development Focus On Business Development Portfolio Expansion & Development Aeterna Labs Founded Zentaris GmbH Acquired Clinical Development ZoptEC Trial Launched Organization Restructuring; focus on reducing burnrate Leaner, More Focused Organization
6 Leadership with Significant Industry Success and Expertise Executive Title Prior Affiliation(s) Years of Experience David Dodd Chairman, CEO Abbott, BMS, Wyeth, Solvay, Serologicals and others 30+ Jude Dinges Senior VP and CCO Merck, Novartis, Amgen 25+ Richard Sachse Senior VP, CMO and CSO Boehringer Ingelheim, Bayer, Schwarz Pharma and UCB 20+ Phil Theodore Senior VP, CAO, General Counsel, Corporate Secretary King & Spalding, Serologicals, BioReliance, John H. Harland and Zep 28+ Dennis Turpin Senior VP and CFO Coopers & Lybrand (now PwC) 25+ 6
7 Strategic Growth Plan Achieve successful commercial presence and growth Successful licensing/acquisition/promotional opportunities Field selling & development of EstroGel & additional products Leverage sales force Utilize collaborations to exploit portfolio value & growth Pursue successful development and commercialization of our internal product portfolio Zoptarelin doxorubicin in oncology Macrilen in endocrinology Become a growth oriented specialty biopharmaceutical company 7
8 Pipeline Supporting Long-Term Growth Product Candidate Discovery Preclinical Phase 1 Phase 2 Phase 3 Zoptarelin doxorubicin Zoptarelin doxorubicin Ovarian (1) and Prostate (2) Cancer Endometrial Cancer Macrilen (macimorelin) AGHD (3) AEZS-120 Prostate Cancer (4) Erk inhibitors LHRH - Disorazol Z Oncology Oncology Compound Library MUSC (5) (1) Phase 2 in ovarian cancer completed. (2) Investigator-driven and sponsored. (3) Confirmatory Phase 3 efficacy trial to be initiated before year-end. (4) Potential oral prostate cancer vaccine available for out-licensing. (5) Compound library transferred to MUSC, Aeterna Zentaris to access future candidates. 8
9 Aeterna Zentaris EstroGel
10 Women s Health EstroGel Non-patch transdermal estrogen therapy product commercialized by Ascend Therapeutics in the US Co-promotion agreement with Ascend in the US Promotion by Aeterna Zentaris sales force in the US on a sales commissions basis Please see full Prescribing Information and boxed warning, or visit for more information about this product. 10
11 EstroGel is Established Worldwide 35 years of worldwide patient use Approved in over 70 countries #1 prescribed estrogen product in Europe #1 prescribed transdermal estrogen product in Canada 11
12 Estrogen Replacement Market $3.6 billion annual US sales (2013) Comprised of oral, transdermal, vaginal, IM products Non-patch transdermal products $100 million annual sales & fastest growing segment Promotionally responsive market Source: Wolters Kluwer 12
13 Aeterna Zentaris EstroGel Goals & Strategy Be #1 in every territory we occupy Sales and promotional campaigns to sustain Ascend s share of voice in the marketplace Expand, defend and further define/differentiate EstroGel in the US marketplace 13
14 Aeterna Zentaris Zoptarelin Doxorubicin
15 Zoptarelin Doxorubicin Targeted Cytotoxic Therapy Zoptarelin Doxorubicin Binding Bypassing the MDR-1 system Internalization Nucleus Migration Apoptosis induction Ref.: Westphalen et al. Int J Oncol
16 Zoptarelin Doxorubicin A Potential Breakthrough in Cancer Therapy Product New Chemical Entity (NCE) composed of a targeted synthetic peptide carrier linked to doxorubicin Value proposition: Improved, targeted delivery of doxorubicin with improved benefit-risk profile Status ZoptEC Phase 3 trial in endometrial cancer currently enrolling in North America, Europe and Israel FDA Special Protocol Assessment (SPA) CRO Ergomed to assume 30% up to $10 million of clinical and reg. costs DSMB recommendation to continue ZoptEC trial following interim analysis, April
17 Zoptarelin Doxorubicin Multiple Potential Applications Tumor Site Endometrium 54,870 Locally advanced, recurrent or metastatic, failure after platinum-taxane Ovary 21,290 Estimated New US Cases 2015 Clinical Evaluation 9,000 Phase 3; ZoptEC trial; NCT (n=500), zoptarelin dox vs doxorubicin Platinum refractory or resistant 14,180 Phase 2; NCT (n=42) Prostate 220,800 Castration and taxane resistant 33,000 Phase 1/2; NCT (n=55) Breast 234,190 Chemotherapy refractory triple negative breast cancer 39,800 Phase 2; NCT Terminated (n=8) Bladder 74,000 Locally advanced unresectable or metastatic 16,000 Phase 1; NCT (n=13) Source: Cancer Facts & Figures 2015, ACS; literature estimates 17
18 Zoptarelin Doxorubicin Compelling Phase 2 Results Tumor Site/Study Endometrium (AGO-GYN5) Zoptarelin Doxorubicin Overall Survival Cardiotoxicity 15.0 months 0/44 reports Overall Survival (Literature data) Doxorubicin Cardiotoxicity (Literature data) Endometrium Thigpen et al. (2004), J Clin Oncol 22: months 7/150 Grade 1 15/150 Grade 2 4/150 Grade 3 2/150 Grade 4 Endometrium Aapro et al. (2003), Annals of Oncology 14: Ovary (AGO-GYN5) 15.6 months 0/42 reports 7.0 months 1/87 Grade 1 1/87 Grade 3 AGO-GYN5: Stratum B : Advanced or recurrent endometrial cancer expressing LHRH receptors Stratum A : Platinum resistant ovarian cancer expressing LHRH receptors 18
19 Addressing Significant Unmet Medical Needs Potentially the first FDA approved medical therapy for treating advanced, recurrent endometrial cancer Providing a medical option for significant unmet medical needs Resulting in rapid adoption as a core therapy for patient treatment & management 19
20 ZoptEC Phase 3 Study Under SPA Randomize ~ 250 patients ~ 250 patients Zopt dox 267 mg/m 2 Day 1 of each cycle Evaluation of response (every 3 cycles) Doxorubicin 60 mg/m 2 Day 1 of each cycle ~ 384 events* (Death) Median OS Median OS Primary Endpoint Overall Survival (OS) Each cycle = 21 days * Pre-planned interim analysis at ~ 128 events & ~ 192 events 20
21 AEZS Commercial Plans in the US Target Medical Oncologists Universe includes 12,500 total 2,000 gynecological oncologists Vertical Oncology Specialty Sales Force Segmented strategy focused on high value targets and key commercial insurers Zoptarelin doxorubicin alone, sales representatives Zoptarelin doxorubicin + in-license brand, sales representatives 21
22 Significant Market Opportunity Potential Estimated US Annual Market Potential Treating Advanced, Recurrent Cancers Endometrial Cancer Other Cancers (Ovarian; Prostate; etc.) $300 million $400 million > $500 million 22
23 Zoptarelin Doxorubicin Next Steps Clinical development Full recruitment of patients (n 500) in H Second interim analysis in H (~192 events) Commercial plan Prepare commercial launch in the US and other territories Establish partnerships in strategic territories (ROW) Out-licensing agreement with Sinopharm A-Think for China, including Hong Kong and Macau Other potential out-licensing agreements to come 23
24 Zoptarelin Doxorubicin Life Cycle Management Strengthen patent protection Process patent filed Reduction of manufacturing costs >50% Following successful development in endometrial cancer therapy Ovarian cancer therapy (phase 2 successfully completed) Prostate cancer therapy (phase 2 ongoing) Additional indications with clinical data (bladder, breast cancer) LHRH-Disorazol Z (new patent protected optimized follow-up molecule) 24
25 Aeterna Zentaris Macrilen TM (Macimorelin)
26 Macrilen TM (Macimorelin) Product Novel orally-active ghrelin agonist that induces a fasting patient s GH secretion Status FDA issued a Complete Response Letter related to the submitted NDA (November 6, 2014) Following successful discussions with the FDA, Aeterna Zentaris announced commitment to rapid clinical development (April 13, 2015) Aeterna Zentaris 26
27 Macrilen TM Strong Value Proposition in AGHD Novel: the only FDA approved product for AGHD (once approved) Accurate: comparable to current standard procedures Safe: well tolerated Convenient vs ITT Oral vs IV/IM injections Simple: single blood draw possible Shorter follow-up Less medical supervision Aeterna Zentaris 27
28 Macrilen TM Next Steps Submit final protocol to FDA and initiate confirmatory Phase 3 efficacy and QT trials Commercial plan for product launch in the US Core sales force of 20 reps 30 centers for GH evaluation in adults 2,500 specialists to target Aeterna Zentaris 28
29 Aeterna Zentaris Committed to Delivering our Goals
30 Focused on Delivering on our Milestones Commercial Development Milestones for 2015 EstroGel revenue growth at 2x segment growth rate Expanding Commercial Portfolio In-licensing, acquisition and/or promotion of additional registered products for commercialization by Aeterna Zentaris Resource & Organizational Improvement Complete implementation of global optimization program to streamline R&D activities, increase commercial activities and overall workforce flexibility STATUS o o o 30
31 Focused on Delivering on our Milestones Zoptarelin doxorubicin Milestones for 2015 Achieve first interim analysis for ZoptEC trial Complete patient recruitment for ZoptEC trial Achieve second interim analysis for ZoptEC trial Macrilen Resolve Go/No Go decision related to clinical development program through FDA interactions Initiate confirmatory Phase 3 efficacy trial Erk Inhibitor Development Program Selection of an optimized molecule for development STATUS o o o o o o 31
32 Vision Transform Aeterna Zentaris from R&D stage to a commercially operating specialty biopharmaceutical company through: Working towards successful development and commercialization of our pipeline Pursuing successful in-/out-licensing opportunities 32
33 Improving Life Transforming Value May 1 st, 2015
Improving Life Transforming Value. May 2015
Improving Life Transforming Value May 2015 Forward Looking Statement This presentation contains forward-looking statements made pursuant to the safe harbor provisions of the U.S. Securities Litigation
More informationImproving Life Transforming Value. October 26, 2015
Improving Life Transforming Value October 26, 2015 Forward Looking Statement This presentation contains forward-looking statements made pursuant to the safe harbor provisions of the U.S. Securities Litigation
More informationThird Quarter, 2015 Update
Third Quarter, 2015 Update November 6, 2015 Forward Looking Statement This presentation contains forward-looking statements made pursuant to the safe harbor provisions of the U.S. Securities Litigation
More informationÆterna Zentaris Inc. EXECUTIVE INFORMATIONAL OVERVIEW April 21, 2015. Company Description. Key Points AEZS NASDAQ
Æterna Zentaris Inc. AEZS NASDAQ EXECUTIVE INFORMATIONAL OVERVIEW April 21, 2015 Company Description Aeterna Zentaris Inc. 1405 du Parc Technologique Boulevard Québec City, Québec G1P 4P5 Canada Phone:
More informationAeterna Zentaris. 11 th Annual Needham Healthcare Conference April 3, 2012. Committed to cure
11 th Annual Needham Healthcare Conference April 3, 2012 Forward-Looking Statements This presentation contains forward-looking statements made pursuant to the safe harbor provisions of the U.S. Securities
More informationManagement's Discussion and Analysis. of Financial Condition and Results of Operations
First Quarter 2015 Management's Discussion and Analysis of Financial Condition and Results of Operations Company Overview Aeterna Zentaris Inc. is a specialty biopharmaceutical company engaged in developing
More informationManagement's Discussion and Analysis of Financial Condition and Results of Operations
Second Quarter 2015 Management's Discussion and Analysis of Financial Condition and Results of Operations Company Overview Aeterna Zentaris Inc. is a specialty biopharmaceutical company engaged in developing
More informationNovel Targeted Immunotherapy Approach for Metastatic Melanoma Under Phase 3 Investigation
Novel Targeted Immunotherapy Approach for Metastatic Melanoma Under Phase 3 Investigation Hans S. Keirstead President, NeoStem Oncology NeoStem Presented by GTC, a conference production company 626-256-6405
More informationDecision to Continue the Development of Tecemotide (L-BLP25) in Non-Small Cell Lung Cancer to be Announced
September 27, 2013 ONO PHARMACEUTICAL CO., LTD. Corporate Communications Phone: +81-6-6263-5670 Decision to Continue the Development of Tecemotide (L-BLP25) in Non-Small Cell Lung Cancer to be Announced
More informationBNC105 CANCER CLINICAL TRIALS REACH KEY MILESTONES CLINICAL PROGRAM TO BE EXPANDED
ASX ANNOUNCEMENT 3 August 2011 ABN 53 075 582 740 BNC105 CANCER CLINICAL TRIALS REACH KEY MILESTONES CLINICAL PROGRAM TO BE EXPANDED Data from renal cancer trial supports progression of the trial: o Combination
More informationAeterna Zentaris. Investor Presentation January 2013
Investor Presentation January 2013 Forward Looking Statement This presentation contains forward-looking statements made pursuant to the safe harbor provisions of the U.S. Securities Litigation Reform Act
More information18.5 Percent Overall Response Rate Observed in Pembrolizumab-Treated Patients with this Aggressive Form of Breast Cancer
News Release Media Contacts: Annick Robinson Investor Contacts: Joseph Romanelli (514) 837-2550 (908) 740-1986 Stephanie Lyttle NATIONAL Public Relations (514) 843-2365 Justin Holko (908) 740-1879 Merck
More informationFlamel Technologies Provides Update on Corporate Progress
Flamel Technologies Provides Update on Corporate Progress Clinical Programs Continue to Move Forward Outlines Full Year 2016 Revenue Guidance Lyon, France January 8, 2016 - Flamel Technologies (NASDAQ:
More informationTheravance Biopharma, Inc. Reports Second Quarter 2015 Financial Results and Provides Business Update
August 10, 2015 Theravance Biopharma, Inc. Reports Second Quarter 2015 Financial Results and Provides Business Update DUBLIN, IRELAND -- (Marketwired) -- 08/10/15 -- Theravance Biopharma, Inc. (NASDAQ:
More informationManagement s Discussion and Analysis of Financial Condition and Results of Operations
Second Quarter 2011 Management s Discussion and Analysis of Financial Condition and Results of Operations Highlights Perifosine April 4, 2011: We announced that two posters on our lead anticancer agent,
More informationA Letter from MabVax Therapeutics President and Chief Executive Officer
A Letter from MabVax Therapeutics President and Chief Executive Officer Dear Fellow Stockholder: You have invested in MabVax Therapeutics because you share our passion for finding new therapies for the
More informationNew Advances in Cancer Treatments. March 2015
New Advances in Cancer Treatments March 2015 Safe Harbour Statement This presentation document contains certain forward-looking statements and information (collectively, forward-looking statements ) within
More informationIMMUNOMEDICS, 300 The American Road, Morris Plains, New Jersey 07950 (973) 605-8200 Fax (973) 605-8282
IMMUNOMEDICS, INC. 300 The American Road, Morris Plains, New Jersey 07950 (973) 605-8200 Fax (973) 605-8282 IMMUNOMEDICS ANNOUNCES FIRST QUARTER FISCAL 2014 RESULTS AND CLINICAL PROGRAM DEVELOPMENTS Morris
More informationAdaptimmune Reports Full Fiscal Year 2015 Financial Results. - Conference call to be held today at 8:00 AM ET (1:00 PM BST) -
Adaptimmune Reports Full Fiscal Year 2015 Financial Results - Conference call to be held today at 8:00 AM ET (1:00 PM BST) - PHILADELPHIA, Pa. and OXFORD, United Kingdom., October 13, 2015 Adaptimmune
More informationPHOTOCURE ASA BUILDING A SPECIALTY PHARMA COMPANY
PHOTOCURE ASA BUILDING A SPECIALTY PHARMA COMPANY RESULTS OF THE FIRST QUARTER 2013 25 April 2013 Kjetil Hestdal, MD, President & CEO Erik Dahl, CFO DISCLAIMER The information included in this Presentation
More informationEPIRUS BIOPHARMACEUTICALS, INC.
EPIRUS BIOPHARMACEUTICALS, INC. FORM 8-K (Current report filing) Filed 09/29/14 for the Period Ending 09/24/14 Address 699 BOYLSTON ST 8TH FLOOR BOSTON, MA 02116 Telephone (617) 600-3497 CIK 0001135906
More informationBreakthrough oral drug delivery technology for diabetes, drugs and vaccines November 5, 2014
Oramed Pharmaceuticals, Inc. Initiating Report Breakthrough oral drug delivery technology for diabetes, drugs and vaccines November 5, 2014 Key data Sector Rating Biotechnology BUY Target Price $45.00
More informationIMMUNOMEDICS, INC. February 2016. Advanced Antibody-Based Therapeutics. Oncology Autoimmune Diseases
IMMUNOMEDICS, INC. Advanced Antibody-Based Therapeutics Oncology Autoimmune Diseases February 2016 Forward-Looking Statements This presentation, in addition to historical information, contains certain
More informationBNC105 PHASE II RENAL CANCER TRIAL RESULTS
ABN 53 075 582 740 ASX ANNOUNCEMENT 19 March 2014 BNC105 PHASE II RENAL CANCER TRIAL RESULTS Results show BNC105 utility in patients with advanced disease Identified biomarkers which correlate with patient
More informationAcucela Inc. IR Meeting
Acucela Inc. IR Meeting Tokyo May 20, 2015 Acucela is a clinical-stage biotechnology company that specializes in discovering and developing novel therapeutics to treat and slow the progression of sight-threatening
More informationAntares Pharma, Inc. Princeton South Corporate Center 100 Princeton South, Suite 300 Ewing, NJ 08628 NASDAQ : ATRS. Paul
Antares Pharma, Inc. Princeton South Corporate Center 100 Princeton South, Suite 300 Ewing, NJ 08628 NASDAQ : ATRS Paul Antares Mission: To develop and commercialize self-administered parenteral medicines
More informationExelixis Showcases R&D Pipeline at JPMorgan Healthcare Conference
Exelixis Showcases R&D Pipeline at JPMorgan Healthcare Conference Two New Clinical Programs and Significant Expansion of Cancer Pipeline Planned for 2004 SOUTH SAN FRANCISCO, Calif., Jan. 13 /PRNewswire-FirstCall/
More informationAffitech A/S reports financial result for the first six months of 2012
Release no. 23/2012 Affitech A/S reports financial result for the first six months of 2012 Clinical trials sites initiated in Russia in late June 2012 by Affitech s collaboration partner IBC Generium for
More informationAvastin in breast cancer: Summary of clinical data
Avastin in breast cancer: Summary of clinical data Worldwide, over one million people are diagnosed with breast cancer every year 1. It is the most frequently diagnosed cancer in women 1,2, and the leading
More informationTransgene Presents Additional Positive Clinical Data from Phase 2b Part of TIME Trial with TG4010 at ESMO
Transgene Presents Additional Positive Clinical Data from Phase 2b Part of TIME Trial with TG4010 at ESMO Statistically significant difference in progression-free survival continues to be seen in non-squamous
More informationOPKO Health to Acquire Bio-Reference Laboratories
OPKO Health to Acquire Bio-Reference Laboratories - Complementary in-depth expertise in diagnostics business with state of the art experience in use of genomic data for personalized therapy - Acquisition
More informationNews Release. Merck KGaA, Darmstadt, Germany, and Pfizer Receive FDA Breakthrough Therapy Designation for Avelumab in Metastatic Merkel Cell Carcinoma
Your Contacts News Release Merck KGaA, Darmstadt, Germany Media: Markus Talanow +49 6151 72 7144 Investor Relations +49 6151 72 3321 Pfizer Inc., New York, USA Media: Sally Beatty +1 212 733 6566 Investor
More informationQ3 2015 Financial Results and Corporate Update. November 4, 2015
Q3 2015 Financial Results and Corporate Update November 4, 2015 Introductions and Forward- Looking Statements Silvia Taylor, SVP Investor Relations and Corporate Affairs Agenda Introductions and Forward-Looking
More informationLocalised Cancer Treatment. PCI Biotech. Amphinex a new product for localised cancer treatment
Localised Cancer Treatment PCI Biotech Amphinex a new product for localised cancer treatment Disclaimer This document (the Presentation ) has been produced by PCI Biotech Holding ASA (the Company ). The
More informationBiotest AG. Company Presentation. July 2013. Company Presentation EU. Biotest AG
Company Presentation July 2013 Disclaimer This document contains forward-looking statements on overall economic development as well as on the business, earnings, financial and asset situation of and its
More informationFORM 6-K. SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549. Report of Foreign Private Issuer
FORM 6-K SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of August 2011
More informationDaiichi Sankyo to Acquire Ambit Biosciences
For Immediate Release Company name: DAIICHI SANKYO COMPANY, LIMITED Representative: Joji Nakayama, Representative Director, President and CEO (Code no.: 4568, First Section, Tokyo Stock Exchange) Please
More informationPfizer Forms Global Alliance with Merck KGaA, Darmstadt, Germany to Accelerate Presence in Immuno-Oncology. November 17, 2014
Pfizer Forms Global Alliance with Merck KGaA, Darmstadt, Germany to Accelerate Presence in Immuno-Oncology November 17, 2014 Forward-looking statements Our discussions during this conference call will
More informationCompany Profile // May 2012
Company Profile // May 2012 1 Disclaimer This presentation has been prepared for the group of companies held by Clal Biotechnology Industries Ltd. (CBI or the Group ) and is provided to you solely for
More information9. WestLB Deutschland Conference. Frankfurt November 16, 2011
9. WestLB Deutschland Conference Frankfurt November 16, 2011 Safe Harbour This presentation includes forward-looking statements. Actual results could differ materially from those included in the forward-looking
More informationCellectar Biosciences
Cellectar Biosciences NASDAQ: CLRB September 2015 1 Safe Harbor Statement This slide presentation contains forward-looking statements. Such statements are valid only as of today, and we disclaim any obligation
More informationMOLOGEN AG. Q1 Results 2015 Conference Call Dr. Matthias Schroff Chief Executive Officer. Berlin, 12 May 2015
Q1 Results 2015 Conference Call Dr. Matthias Schroff Chief Executive Officer Berlin, 12 May 2015 V1-6 Disclaimer Certain statements in this presentation contain formulations or terms referring to the future
More informationARIAD Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter)
UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event
More informationFirst Quarter 2015 Earnings Teleconference. April 28, 2015
First Quarter 2015 Earnings Teleconference April 28, 2015 Introduction Chuck Triano Senior Vice President, Investor Relations Forward-Looking Statements and Non-GAAP Financial Information Our discussions
More informationHeat Biologics, Inc. (Exact name of registrant as specified in charter)
UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (date of earliest event
More informationCompany Presentation
Company Presentation DISCLAIMER This document contains forward-looking statements on overall economic development as well as on the business, earnings, financial and asset situation of amp biosimilars
More informationALLOS THERAPEUTICS, INC. 2000 ANNUAL REPORT. Building an. Oncology Franchise
ALLOS THERAPEUTICS, INC. 2000 ANNUAL REPORT Building an Oncology Franchise Allos is a product company that develops and commercializes small molecule oncology and cardiovascular drugs. Our lead product
More informationLOOKING FORWARD PUMA BIOTECHNOLOGY, INC. 2014 ANNUAL REPORT
LOOKING FORWARD PUMA BIOTECHNOLOGY, INC. 2014 ANNUAL REPORT Puma Biotechnology, Inc. is a development stage biopharmaceutical company that acquires and develops innovative products for the treatment of
More informationPROMETIC LIFE SCIENCES INC.
PROMETIC LIFE SCIENCES INC. Investor Update July to September 2002 This present release must be considered as the quarterly report to shareholders. 1. Letter to Shareholders Dated November 21, 2002 2.
More informationDr. Reddy s Q3 and 9M FY16 Financial Results
Press Release DR. REDDY'S LABORATORIES LTD. 8-2-337, Road No. 3, Banjara Hills, Hyderabad - 500034. Telangana, India. INVESTOR RELATIONS KEDAR UPADHYE kedaru@drreddys.com (Ph: +91-40-66834297) CONTACT
More informationCATAMARAN CORPORATION ANNOUNCES RECORD FINANCIAL RESULTS FOR 2014 CATAMARAN TO ACQUIRE HEALTHCARE SOLUTIONS, INC.
CATAMARAN CORPORATION ANNOUNCES RECORD FINANCIAL RESULTS FOR 2014 CATAMARAN TO ACQUIRE HEALTHCARE SOLUTIONS, INC. Schaumburg, Illinois, February 26, 2015 - Catamaran Corporation ( Catamaran or the Company
More informationAvastin in breast cancer: Summary of clinical data
Avastin in breast cancer: Summary of clinical data Worldwide, over one million people are diagnosed with breast cancer every year 1. It is the most frequently diagnosed cancer in women 1,2, and the leading
More informationImmunovaccine Inc. (TSX-V: IMV) July 2011
Immunovaccine Inc. (TSX-V: IMV) July 2011 2 Forward Looking Statements This document contains forward-looking information pursuant to applicable securities law. All information that addresses activities
More informationPain Therapeutics, Inc.
Pain Therapeutics, Inc. Pioneers in Preventing Prescription Drug Abuse Remi Barbier President & CEO June 2014 1 Forward-Looking Statements This presentation contains forward-looking statements within the
More informationCellectar Biosciences
Cellectar Biosciences NASDAQ: CLRB October 2015 1 Safe Harbor Statement This slide presentation contains forward-looking statements. Such statements are valid only as of today, and we disclaim any obligation
More information2016 Q1 Earnings Conference Call. 2015 TeraGo Networks Inc.
2016 Q1 Earnings Conference Call Forward Looking Statements This presentation includes certain forward-looking statements that are made as of the date hereof and are based upon current expectations, which
More informationKempen & Co 4 th Healthcare/Life Sciences Conference. Brussels March 29, 2011
Kempen & Co 4 th Healthcare/Life Sciences Conference Brussels March 29, 2011 Safe Harbour This presentation includes forward-looking statements. Actual results could differ materially from those included
More informationAn integrated global healthcare company
An integrated global healthcare company 1 A Mission to create healthier communities globally Zydus Cadila is dedicated to life In all its dimensions. Our world is shaped by a passion for innovation, commitment
More informationTeva and Checkpoint Therapeutics Announce License Agreement for Oral PARP Inhibitor
Teva and Checkpoint Therapeutics Announce License Agreement f Oral PARP Inhibit Checkpoint to Obtain Exclusive Wldwide Development and Commercialization Rights Jerusalem and New Yk, NY, January 7, 2016
More informationThe Ultimate Healthcare & Biotechnology Event in 2010. Deborah Rathjen CEO & Managing Director 24 March 2010
The Ultimate Healthcare & Biotechnology Event in 2010 Deborah Rathjen CEO & Managing Director 24 March 2010 Safe Harbor Statement Factors Affecting Future Performance This presentation contains "forward-looking"
More informationFlamel Technologies Announces Second Quarter Results of Fiscal Year 2015
Flamel Technologies Announces Second Quarter Results of Fiscal Year 2015 Product revenue guidance for 2015 of $170-$185 million reaffirmed Conference call with management to take place at 10:00 am ET on
More informationSPHERIX INCORPORATED (Exact name of registrant as specified in its charter)
UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event
More informationInvestor Presentation NASDAQ:BLFS
Investor Presentation NASDAQ:BLFS Safe Harbor Statement This presentation contains forward-looking statements, including, but not limited to, statements concerning the company s anticipated business and
More informationDetecting Cancer in Blood. Company presentation
Detecting Cancer in Blood Company presentation Safe harbor statement Forward Looking Statements This communication contains certain forward-looking statements, including, without limitation, statements
More information2009 Foley & Lardner LLP Attorney Advertising Prior results do not guarantee a similar outcome Models used are not clients but may be representative
Attorney Advertising Prior results do not guarantee a similar outcome Models used are not clients but may be representative of clients 321 N. Clark Street, Suite 2800, Chicago, IL 60654 312.832.4500 Life
More informationMedical Billing and the Advantages of a Novelized Pharmaceutical Program
FOR IMMEDIATE RELEASE Compugen Ltd. Reports Fourth Quarter and Calendar 2015 Results Holon, ISRAEL February 9, 2016 Compugen Ltd. (NASDAQ: CGEN), a leading predictive drug discovery company, today reported
More informationTERM SHEET EXAMPLE. 1 P age
1 P age TERM SHEET EXAMPLE BIOTECHCO Overview & Business Strategy BIOTECHCO (the licensor), located in North Dakota, has a proprietary technology called ZIP that can generate fully human antibodies with
More informationThe Future of Consumer Health Care
The Future of Consumer Health Care Coming Together To Lead The Consumer Health Care Industry 2 Creating a New Business Model in Consumer Health Care 3 Serve More Consumers In More Parts of the World, More
More informationGalapagos reports largest cash balance ever
Regulated information 3 March 2016, 22.00 CET Galapagos reports largest cash balance ever Key 2015 financials: Cash burn of 122 million, in line with guidance Cash balance on 31 December 2015 of 348 million
More informationBlackBerry Reports 2015 Fiscal First Quarter GAAP Profitability
NEWS RELEASE FOR IMMEDIATE RELEASE June 19, BlackBerry Reports 2015 Fiscal First Quarter GAAP Profitability Waterloo, ON BlackBerry Limited (NASDAQ: BBRY; TSX: BB), a global leader in mobile communications,
More informationAn introduction to Optos
An introduction to Optos Building The Retina Company Roy Davis, CEO Christine Soden, CFO 1 Forward-Looking Statements Certain statements made in this presentation are forward-looking statements. These
More informationGuidance for Industry FDA Approval of New Cancer Treatment Uses for Marketed Drug and Biological Products
Guidance for Industry FDA Approval of New Cancer Treatment Uses for Marketed Drug and Biological Products U.S. Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation
More informationNEW CHEMICAL ENTITIES
NEW CHEMICAL ENTITIES PIONEERING PARTNER FOR PEPTIDES With more than 40 years of expertise in peptide synthesis, a track record in process development, large-scale manufacturing and outstanding product
More informationProactive Investors February 13, 2013. Enhancing lives and improving drugs
Proactive Investors February 13, 2013 Enhancing lives and improving drugs Disclaimer The information contained in this presentation and to be communicated during the management presentation based upon
More informationCAN-FITE BIOPHARMA LTD.
UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 Under the Securities Exchange Act of 1934 For the Month
More informationCompany Presentation June 2011 Biotest AG 0
Company Presentation June 2011 0 Disclaimer This document contains forward-looking statements on overall economic development as well as on the business, earnings, financial and asset situation of and
More informationAdaptimmune Growth Leads to Long-Term Expansion Plans in Philadelphia
Adaptimmune Growth Leads to Long-Term Expansion Plans in Philadelphia Company Selects The Navy Yard as Site for U.S. Headquarters and Base for Clinical and Manufacturing Operations PHILADELPHIA, Pa and
More informationDeutsches Eigenkapitalforum. Frankfurt November 22, 2011
Deutsches Eigenkapitalforum Frankfurt November 22, 2011 Safe Harbour This presentation includes forward-looking statements. Actual results could differ materially from those included in the forward-looking
More informationThe world leader in photodynamic technology
Brilliance in photodynamic technology TM The world leader in photodynamic technology Presentation of third quarter 2010 results 27 October 2010 Kjetil Hestdal, President & CEO Christian Fekete, CFO The
More information2014 Onxeo Review and 2015 Perspectives
2014 Onxeo Review and 2015 Perspectives 2014 Consolidated Financial Results - Successful strategic merger and acquisition of Danish company Topotarget giving birth to Onxeo - Products major achievements:.
More informationTuesday, January 13, 2015 8:30 a.m. ET / 7:30 a.m. CT / 6:30 a.m. MT / 5:30 a.m. PT
FIRST QUARTER EARNINGS CONFERENCE CALL Tuesday, January 13, 2015 8:30 a.m. ET / 7:30 a.m. CT / 6:30 a.m. MT / 5:30 a.m. PT The dial-in number for the conference call is 1.800.768.2950 (toll-free North
More informationSTRATEGY PROGRAM NEXT LEVEL BERLIN, 9 JUNE 2016
STRATEGY PROGRAM NEXT LEVEL BERLIN, 9 JUNE 2016 Disclaimer Certain statements in this presentation contain formulations or terms referring to the future or future developments, as well as negations of
More informationSORRENTO THERAPEUTICS, INC.
ˆ200F@WVSVmdG1Yng+Š 200F@WVSVmdG1Yng+ AZ0151AC599817 11.3.10 SWRvelaj0nb 31-Jul-2013 16:51 EST 577580 TX 1 3* UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 CURRENT REPORT Pursuant
More informationData from an interim analysis from the pivotal Phase 3 trial of YONDELIS in soft tissue sarcoma, SAR-3007, will be presented in an oral presentation
PharmaMar announces new advances in oncology at ASCO 2015 for its compounds YONDELIS and PM1183 in small cell lung cancer, soft tissue sarcoma, and mesothelioma Compelling clinical activity of PM1183 in
More informationANTARES PHARMA. Paul K. Wotton Ph.D. President and Chief Executive Officer. Jefferies 2014 Global Healthcare Conference Wednesday June 4, 2014
ANTARES PHARMA Paul K. Wotton Ph.D. President and Chief Executive Officer Jefferies 2014 Global Healthcare Conference Wednesday June 4, 2014 NASDAQ:ATRS 1 Safe Harbor Statement This presentation may contain
More informationThe Board reviews risks to the Company s business plan at its scheduled meetings.
Pharmaxis Ltd 1. Board responsibility The Pharmaxis Board is responsible for ensuring the Company establishes and maintains a risk management framework for the oversight and management of risk. The Board
More informationCommerzbank Sector Conference. Frankfurt August 30, 2011
Commerzbank Sector Conference Frankfurt August 30, 2011 Safe Harbour This presentation includes forward-looking statements. Actual results could differ materially from those included in the forward-looking
More informationMOLOGEN AG German Equity Forum 2015
German Equity Forum 2015 Dr. Mariola Söhngen Chief Executive Officer Frankfurt am Main 24 November 2015 We are Pioneers in the Field of Immunotherapies Biotechnology company with focus on immunotherapies
More information2014 Wells Fargo Healthcare Conference June 17, 2014 NYSE: Q
2014 Wells Fargo Healthcare Conference June 17, 2014 NYSE: Q Copyright 2013 Quintiles Forward Looking Statements and Use of Non-GAAP Financial Measures This presentation contains forward-looking statements
More informationWILEX AG: Interim management statement on the first quarter of 2016
WILEX AG: Interim management statement on the first quarter of 2016 Munich, Germany, 14 April 2016. WILEX AG (ISIN DE000A11QVV0 / WL6 / FSE) today reported on the first three months of the 2016 financial
More informationRecommended Acquisition of Networkers International plc Presentation to Analysts & Investors
Recommended Acquisition of Networkers International plc Presentation to Analysts & Investors 28 January 2015 Disclaimer THIS PRESENTATION IS NOT AN OFFER OR SOLICITATION OF AN OFFER TO BUY OR SELL SECURITIES.
More informationPaul K. Wotton, Ph.D President and Chief Executive Officer May 2012 AMEX: AIS
Paul K. Wotton, Ph.D President and Chief Executive Officer May 2012 AMEX: AIS Safe Harbor Statement This presentation may contain forward-looking statements which are made pursuant to the safe harbor provisions
More informationTreatment of Metastatic Breast Cancer: Endocrine Therapies. Robert W. Carlson, M.D. Professor of Medicine Stanford University
Treatment of Metastatic Breast Cancer: Endocrine Therapies Robert W. Carlson, M.D. Professor of Medicine Stanford University MDACC Experience with FAC in Chemotherapy-Naive MBC Greenberg et al, J Clin
More informationPresented at: Jefferies 2015 Global Healthcare Conference
Presented at: Jefferies 2015 Global Healthcare Conference Agenda 1 Overview & Service Platforms 2 Adaptability, Scalability & Expansion Plans 3 Best Practices 4 Blue Chip Customer Base 5 Roadmap of Evolution
More informationMorphoSys Proprietary Development Update
September 8, 2015 MorphoSys Proprietary Development Update 1 Safe Harbor This presentation includes forward-looking statements. Actual results could differ materially from those included in the forward-looking
More information(1) MAJOR TRANSACTION ACQUISITION OF FURTHER EQUITY INTERESTS IN SHANGHAI CP GUOJIAN PHARMACEUTICAL CO., LTD.; AND (2) CHANGE IN USE OF PROCEEDS
Hong Kong Exchanges and Clearing Limited and The Stock Exchange of Hong Kong Limited take no responsibility for the contents of this announcement, make no representation as to its accuracy or completeness
More informationEigenkapitalforum 2013. Company Update November 12, 2013
Eigenkapitalforum 2013 Company Update November 12, 2013 Safe Harbour This presentation includes forward-looking statements. Actual results could differ materially from those included in the forward-looking
More informationTABLE OF CONTENTS. Introduction...1. Chapter1 AdvancesinTreatment...2. Chapter2 MedicinesinDevelopment...11. Chapter3 ValueandSpending...
CANCER TABLE OF CONTENTS Introduction...1 Chapter1 AdvancesinTreatment...2 Chapter2 MedicinesinDevelopment......11 Chapter3 ValueandSpending......15 Chapter4 Conclusion...22 INTRODUCTION Researchers and
More informationBayer Invests Heavily in R&D and is committed to innovation Sustained Innovation Output from all Subgroups
Open Innovation@BayerHealthCare Dr. Daniel Forler External Innovation Therapeutics Global Drug Discovery, Bayer HealthCare ASTP-Proton Conference Page 1 Bayer Invests Heavily in R&D and is committed to
More informationWeek 12 study results
Week 12 study results 15 April 2015 Copyright 2015 Galapagos NV Disclaimer This document may contain certain statements, including forward-looking statements, such as statements concerning the safety and
More information