1 Asbestos : the legacy remains and will still go on Rob Armstrong Hawkes Bay District Health Board
2 Early uses of asbestos
3 Asbestiform minerals richterite winchite erionite : limited industrial use
4 Samuel Turner ( )
5 Asbestos is one of the most marvellous productions of inorganic nature a physical paradox that combines the properties of rock and silk, and can be spun into strands that weighed less than an ounce and up to a hundred yards R H Jones : Asbestos and Asbestic 1897 Fibrous tremolite on muscovite
6 So what happens if you breath in some asbestos?
7 The asbestos related diseases or ARDs Benign pleural disease : pleural plaque pleural thickening pleural effusion Pulmonary parenchymal disease : fibrosis (asbestosis) Malignant disease : oro-pharyngeal cancer lung cancer mesothelioma (pleural or peritoneal cancer) oesophageal cancer bowel cancer bladder cancer ovarian cancer
8 Lung Cancer All types of cancer associated with asbestos exposure. Smokers have a seven times increased risk compared to non-smokers. Smokers with asbestos exposure have a fifty times greater risk of malignancy.
9 Mesothelioma The prime marker of asbestos exposure Aggressive disease Long latency Poor prognosis Minimal therapeutic options
10 Chance of developing the condition Mesothelioma? Lung cancer Asbestosis Pleural plaque Threshold Total lung dust burden
11 1898 H M Factory Inspectorate report.
12 (Sir) Richard Doll et al "Mortality from lung cancer" BJIM 1953 Wagner et al "Diffuse pleural mesothelioma and asbestos exposure in the North Western Cape Province" BJIM 1960 Irving Selikoff et al Asbestos exposure and Neoplasia JAMA 1964
13 The Lord Denning Judgement 1971 Alice. A fight for life BBC 1982
14 The Asbestos Industry The Government Health Authorities The workers in the industry
15 The Asbestos Industry The Government Health Authorities The workers in the industry
17 FIGURE 1. Asbestos use and permissible exposure limits* --- United States, CDC MMWR April 24, 2009 / 58(15);
18 World-wide action on controlling asbestos Brazil : total ban on utilizing asbestos from 2007 BUT is 4 th largest exporter of asbestos to developing countries Canada : still exports asbestos to Asian markets (5 th in world) France : banned all asbestos use in 1997 : called for worldwide ban in 2000 India : no restriction on asbestos use currently : in 2011 Indian Supreme Court refused to countenance any control measures on asbestos Italy : banned asbestos in 1992 and removed asbestos from all buildings Japan : delayed banning asbestos until 2004 Unites States : the Environmental Protection Agency has no general ban on the use of asbestos : the Toxic Substances Control Act prohibits certain applications. A senate sub-committee in 2001 turned down an appeal from scientists, doctors and members of the public to ban asbestos. In 2010, Washington State banned the use of asbestos in vehicle brakes, starting in 2014.
19 Wittenoom Mining of blue asbestos began in 1939 and the industry boomed through the 50 s and 60 s.
20 James Hardie established an asbestos-cement factory in Penrose in Production continued until 1987, although from 1983 asbestos was only used in pipes. Chrysotile was mined in Takaka from Imported asbestos over the course of 40 years was predominantly Canadian chrysotile, with small amounts of Australian or South African crocidolite Fletchers established a factory in Riccarton in 1943 (Durock Industries) which closed in 1974
21 1951 Dr Garland : annual report to Minister of Health : concerns that proper precautions to minimize dust exposure at Takaka were not being taken 1953 Notification system for occupational disease introduced 1960 Occupational Health Notes (DoH) comments on occurrence of asbestosis and increased incidence of bronchogenic carcinoma 1968 Drs Copplestone and Allingham report a survey of 207 workers : 107 X-rayed, 17 had plaque, 1 had asbestosis 1981 Fibre limits reduced to 1 f/ml for chrysotile, 0.2 f/ml for crocidolite
22 Kjellstrom and Rennie report on workers at James Hardie : it remains unpublished Kier Howard (NZMJ) looks at relative cancer risks from different types asbestos (Review article) 1988 Assoc Prof Glass and OHN interview ex-workers from Fletchers in Mandeville St (unpublished) : 103 workers, 87 investigated, 47 ARD, 12 deaths noted Hon Bill Birch establishes Asbestos Advisory Panel to monitor and report on all aspects of asbestos use in NZ 1992 National Asbestos Registers established : for exposed personnel and for ARD victims.
23 Registrants to the Exposure Register for persons involved in the aftermath of the Feb 2010 quake
30 The legacy of asbestos : 1. Long latency to development of disease 2. Residual asbestos in buildings and environment 3. Ongoing use of asbestos in developing nations
31 Long latency Asbestosis : US data for adults 15 years and older Source : CDC (NIOSH)
32 Long latency
33 Asbestosis deaths and disablement benefit cases In 2009 there were 411 deaths where asbestosis is likely to have contributed as a cause compared with 109 in There were 189 deaths in 2009 where asbestosis was specifically recorded as the underlying cause of death. - Numbers of newly assessed cases for Industrial Injuries Disablement Benefit have increased more rapidly than asbestosis deaths in recent years. - The number of newly assessed cases for 2010 was UK Health and Safety Executive 2010
34 Mesothelioma deaths and disablement benefit cases Over 80% of deaths were among men. - Men who worked in the building industry when asbestos was still being used widely are now among those most at risk of mesothelioma. - Most deaths among women are likely to be due to a range of non-occupational asbestos exposures. - The worst case predictions for males are that annual deaths will increase to a peak of about 2,100 in about the year Female deaths are likely to peak after this but at a much lower level. UK Health and Safety Executive 2010
35 Asbestos-related lung cancer The overall scale of asbestos related lung cancer deaths has to be estimated because it is difficult to tell these cancers apart from those due to smoking. The latest information shows: - There are probably about as many asbestos-related lung cancer deaths each year as there are mesothelioma deaths. - This implies there are currently about deaths each year in Great Britain due to asbestos-related lung cancer. - The ratio of lung cancers to mesotheliomas is expected to fall over time suggesting less than one asbestos related lung cancer per mesothelioma in the future. UK Health and Safety Executive 2010
36 Projection of mesothelioma mortality in Britain using Bayesian methods E Tan, N Warren, A J Darnton and J T Hodgson British Journal of Cancer (2010) 103,
37 From the 1870s until 1956, Armley (West Yorkshire) was home to the J W Roberts (subsequently T & N) asbestos mattress and boiler lining factory. The factory (red rectangle) exposed local residents (yellow pentagon) to asbestos fibres and resulted in a mesothelioma cancer cluster which persists to this day
38 Distribution of asbestos contamination with place of residence for 96 mesothelioma victims. :plant Courtesy Prof Ken Takahashi
39 Residual asbestos in buildings and environment
40 11 September 2001 : 1,000 tons of asbestos
42 Christchurch 22 February 2011
43 Asia s emerging asbestos epidemic Syed Aljunid United Nations University The clearest warning yet on ARDs in Asia. Data availability still a hindrance on the two most populous nations.
44 Courtesy of Prof Ken Takahashi
47 Courtesy Prof Ken Takahashi
49 The Chongquing plant opened in 1939 and expanded rapidly between using up to 6,000 tonnes of asbestos annually. Only chrysotile from the Sichuan mines was used : analysis of samples in 2000 was unable to detect any tremolite contamination. This is a 37 year retrospective cohort study in which asbestos workers mortality data was compared to a reference group of workers in an electronics factory established at the same time in that city. Thorax :
50 Fig 1 Kaplan-Meir curves for cumulative survival from all cancers and lung cancer in asbestos workers and controls Thorax :
51 The findings from the Chingquong study show a more than threefold increase in the risk of death from lung cancer (and also nonmalignant respiratory disease) in the asbestos workers after statistical control for smoking. There was clear evidence of an exposure-response relationship in both smokers and non-smokers. This argues against the amphibole hypothesis as the asbestos was pure chrysotile. The asbestos disease epidemic is not over : it has simply moved to other nations, and occupational health workers all over the world have an obligation to ensure it does not repeat itself. Thorax :
52 Can the use of asbestos ever be controlled to the extent that it is safe in mining, processing and in subsequent placement in the environment, where it will be safe for future generations?
53 Asbestos: elimination of asbestos-related diseases Fact sheet N 343 July 2010 Key facts: About 125 million people in the world are exposed to asbestos at the workplace. According to WHO estimates, more than people die each year from asbestos-related lung cancer, mesothelioma and asbestosis resulting from occupational exposure.
1 Asbestos: The current situation in Europe Laura, Salvatori Tillinghast Towers Perrin 71 High Holborn London WC1V 6TH United Kingdom Tel no: +44 207 170 2000 Fax no.: +44 207 170 2222 E-mail: email@example.com
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