Diagnosis 2.0 Towards a new paradigm for personalized mental health care. Marieke Wichers, Psychiatry & Psychology, Maastricht

Size: px
Start display at page:

Download "Diagnosis 2.0 Towards a new paradigm for personalized mental health care. Marieke Wichers, Psychiatry & Psychology, Maastricht"

Transcription

1 Diagnosis 2.0 Towards a new paradigm for personalized mental health care Marieke Wichers, Psychiatry & Psychology, Maastricht

2 Tijd voor een nieuw paradigma in de psychiatrie 1. Van focus op het negatieve naar focus op het positieve, herstel en kracht 2. Van traditionele statische denkwijze naar complex dynamische manier van denken over psychiatrie 3. Van werken met groepsresultaten naar persoons-specifieke mechanismen

3 Experience Sampling Methodology 1. Multiple assessments 2. Real world 3. In het moment 4. Evaluation of context ESM procedure Dag 1 Dag 2 Dag 3 Dag 4 Dag 5 Een ESM dag uur Prospective!!!

4 1. ESM as a clinical tool: a focus on positive emotions NEW TECHNOLOGICAL DEVELOPMENTS!!! Data immediately available and opportunities for implementation in mental health care

5 Therapeutic application of ESM 7 6 positive affect Moments of resilience against depression? Context

6 ESM intervention in depression: RCT N=102 depressive patients Experimental n=33 Pseudo-experimental n=36 Controle n=33 6 weeks TAU+ESM+feedback 6-weeks TAU+ESM TAU Depressive 1 week, 1,2,3 & 6 months Kramer, Simons, et al, World Psychiatry, 2014

7 ESM intervention: Feedback protocol Type of Activities Activity & Positive Affect PA per type of activity active relaxation doing nothing/resting talking eating/drinking household activities passive relaxation work/study self care on the way active relaxation passive relaxation doing nothing/resting work/study talking self care eating/drinking on the way household not at all much PA Kramer, Simons, et al, World Psychiatry, 2014

8 Efficacy Depression * Clinical: HDRS Self-report: IDS Intervention Follow-up * * * * * * * Kramer, Simons, et al, World Psychiatry, 2014

9 17 ESM intervention in depression: RCT HDRS sum score predicted control group predicted pseudoexperimental predicted experimental Time since pre-assessment (weeks) Kramer, Simons, et al, World Psychiatry, 2014

10 Results Costs over 32 weeks ESM-I (n=33) Pseudo (n=35) TAU (n=33) Health care perspective Societal perspective Intervention alone No differences in costs between the groups Utilities over 32 weeks ESM-I Pseudo TAU EuroQol 0.17 (0.06) 0.13 (0.08) 0.12 (0.07) ESM-I better than TAU. B=0.03, p=0.047 HDRS at 32 weeks ESM-I Pseudo TAU HDRS 10.8 (7.1) 13 (7.12) 15.3 (8.3) Symptomatic remission 11 (45.8) 9 (32.1) 5 (20.0) ESM-I subjects more in remission than TAU. OR=2.8, p=0.09 HDRS results see introduction

11 22 Figure 1. Cost-effectiveness acceptability curve of the base-case 32 week follow-up costutility analysis with the bootstrapped societal costs and EQ-5D-based QALYs 100% Probability cost-effective 80% 60% 40% % CNTR PSEU INTERV 20% 0% Cost-effectiveness threshold Healthy Maximum

12 2. ESM: zooming in to smallest building blocks: mechanisms and diagnostics 1. Multiple assessments 2. Real world 3. In het moment 4. Evaluation of context ESM procedure Dag 1 Dag 2 Dag 3 Dag 4 Dag 5 Een ESM dag uur

13 ESM: micro-level processing may produce a cascase of effects Insecure down cheerful suspicious content Wichers 2013, Psychological Medicine

14 Dynamiek op micro-niveau LAGE connectiviteit in het netwerk HOGE connectiviteit in het netwerk Wichers, Wigman, Myin-Germeys, submitted

15 Diagnostics: TOP DOWN network approach Healthy people (n=207) Depressed people (n=129) Cheerful Cheerful Suspicious Content Suspicious Content Down Insecure Down Insecure Wigman et al, submitted

16 Diagnostics: TOP DOWN approach Psychotic people (n=263) Depressed people (n=129) Cheerful Cheerful Suspicious Suspicious Content Content Down Insecure Down Wigman et al, submitted Insecure

17 BOTTOM UP APPROACH TOP-DOWN BOTTOM UP Category 1 Category 2 Category 3 Empirical approach

18 Subgroeps of individuals? Or subgroups of network parts?

19 BOTTOM UP APPROACH 1. Impact of positive emotions 2. Impact of feeling down 3. Healthy suspicion 4. Balance between active and passive positive emotions 5. Impact of feeling insecure 6. Negative mood reactivity 7. Unhealthy suspicion

20 t 0 stress NA PA social active behaviour behaviour genes Stress genes t 1 1 t 2 PA 2 3 NA t 3 genes t 4 t 5 4 Social interaction 5 Active behaviour genes Wichers 2013, psychological medicine

21 Stress in the network : real data! Sample: 129 individuals with residual symptoms of major depression ESM: 5 days, 10 measurements a day with an average of 90 minutes in between Baseline assessment of MBCT trial Social stress Positive affect Negative affect Social engagement 4 5 Active engagement Wichers 2013, psychological medicine

22 MINDMAASTRICHT: RCT Sample: 130 participants with residual symptoms of depression, not currently depressed 6 days Experience Sampling Questionnaires Mindfulness Training (8 weeks) + TAU TAU 6 days Experience Sampling Questionnaires 4 5 Geschwind N, Peeters F, Drukker M, van Os J, Wichers M. J Consult Clin Psychol Oct;79(5): FU 6 months FU 12 months

23 MBCT impacts on PA related outcomes Geschwind et al, J. Consulting & Clinical Psychology, 2011

24 Increase in Positive Affect is associated with change in depressive symptoms Geschwind et al 2011 J Clin Consult Psychol

25 3. ESM: person-specific assessment of early warning signals Personalized analyses

26

27 Predicting critical transitions in complex dynamical systems Scheffer et al, Nature

28 van der Leemput, Wichers et al, PNAS Early warning signals if close to transition: - increased variance - Increased autocorrelation t t+1 t t+1 - Increased connectivity Cramer et al, submitted

29 Prediction of future shifts in a single system with ESM data Case-experiment in an individual on antidepressants. Can I stop taking antidepressants? Wichers, Groot et al, in preparation

30 Change point analyses package ecp in R

31 2,8 depressive symptoms SCL-90 Time period before transition Time window of transition Time period directly following transition 2,6 2,4 2,2 2 1,8 1,6 1,4 1, ,4 negative affect autocorrelation 0,35 0,3 0,25 0,2 Wichers, Groot, Scheffer ( ) Borsboom, in preparation 0,15 0,1 0,

32 Prediction of future shifts with changes in the network Increased connectivity? Wichers, Groot, Scheffer ( ) Borsboom, in preparation

33 suspicion Positive affect 1. Before experiment Mental unrest 2. Double-blind: no reduction AD worry Negative affect 3. Double-blind: reduction AD 4. After reduction; before shift

34 https://www.dropbox.com/sh/5kbity7i6b644to/nkqyirjgx4

35 Diagnose 2.0: de inzet van ESM in mentale gezondheidszorg Focus op kracht, weerbaarheid en eigen betrokkenheid bij herstel Complementaire manier om gedetailleerd de kleinste betrokken bouwstenen van psychopathologie te observeren Complementaire persoons-specifieke informatie over mechanismen en risico voor transitie

36 Mobile app en web-app Patient makes own diagnosis Patient assesses change Learning about mood in relation to daily life circumstances Implicit mood patterns made explicit (life or delayed feedback) Patient and clinician share the outcome of the assessment information: it collaboratively leads to informed decisions improved patient engagement & empowerment

37 We have: Support for (cost-)effectiveness in RCT Research supporting underlying theories regarding vision on diagnostics, positive affect and complex dynamics Statistical tools to deal with complexity: time series, network analyses Proof of principle for single case monitoring ESM-I implementation - large pragmatic observational trial - GP, primary, specialized care (cost)effectiveness in mental health care?

38 Met dank aan: Denny Borsboom Peter Groot Marten Scheffer Kenneth Kendler Hanneke Wigman Jim van Os Philippe Delespaul Inez Myin-Germeys en de onderzoeksgroep div Mental Health, Maastricht

39 Table S1. Mean ratings on the Use of the Psymate debriefing questionnaire addressing the feasibility of the PsyMate as an experience sampling device Use of the PsyMate Acceptance of the PsyMate Mean (min-max) (Scale 1-7) N (subje cts) SD All groups Was the text on screen well readable? 5.8 (2-7) Was it difficult to switch PsyMate on? 1.6 (1-6) Was the PsyMate difficult to control? 1.4 (1-5) Were the verbal instructions you received about using the PsyMate clear? 6.6 (3-7) Were the written instructions you received with the PsyMate clear? 6.5 (1-7) Were the questions you answered on the PsyMate difficult or unclear? 2.6 (1-6) Did you find it annoying or stressful to use the PsyMate? With respect to the number of s per day 3.1 (1-7) With respect to the time it took to answer the questions for a single 2.5 (1-7) With respect to the noises/sound volume 2.0 (1-7)

Effects of Mindfulness-Based Cognitive Therapy on the experience of positive emotions in daily life: A randomized controlled trial

Effects of Mindfulness-Based Cognitive Therapy on the experience of positive emotions in daily life: A randomized controlled trial Effects of Mindfulness-Based Cognitive Therapy on the experience of positive emotions in daily life: A randomized controlled trial Nicole Geschwind nicole.geschwind@kuleuven.be Centre for Psychology of

More information

* * * * * * Health gains are meaningless if there is no opportunity. Therefore: combat Stigma. The European AO Situation

* * * * * * Health gains are meaningless if there is no opportunity. Therefore: combat Stigma. The European AO Situation Which Philosophy to Guide Psychiatry Prof. dr. J. van Os Nature, 0 Societal Changes 00 Psychiatric beds - Western Europe Psychiatric hospital beds per 00000 Health gains are meaningless if there is no

More information

Psymate en psychose: onderzoek en innovatie Prof. Inez Myin-Germeys

Psymate en psychose: onderzoek en innovatie Prof. Inez Myin-Germeys Psymate en psychose: onderzoek en innovatie Prof. Inez Myin-Germeys Prof. of Ecological Psychiatry School for Mental Health & Neuroscience De context van ervaringen MHENS School for Mental Health and Neuroscience

More information

The complexity of psychopathology:! A network approach

The complexity of psychopathology:! A network approach The complexity of psychopathology:! A network approach Denny%Borsboom% University%of%Amsterdam www.psychosystems.org Overview The network idea! Conceptual consequences:! Disorders and their boundaries!

More information

EFFECTIVENESS OF INPA TIENT TREATMENT PROGRAMS F OR DUALLY DIAGNOSED PAT IENTS.

EFFECTIVENESS OF INPA TIENT TREATMENT PROGRAMS F OR DUALLY DIAGNOSED PAT IENTS. FEDERAL SCIENCE POLICY. EFFECTIVENESS OF INPA TIENT TREATMENT PROGRAMS F OR DUALLY DIAGNOSED PAT IENTS. Promoter: Professor B. Sabbe (Universiteit Antwerpen). Researcher: B. De Wilde (Universiteit Antwerpen).

More information

Psychosocial treatment of late-life depression with comorbid anxiety

Psychosocial treatment of late-life depression with comorbid anxiety Psychosocial treatment of late-life depression with comorbid anxiety Viviana Wuthrich Centre for Emotional Health Macquarie University, Sydney, Australia Why Comorbidity? Comorbidity is Common Common disorders,

More information

Mindfulness-based Cognitive Therapy for Recurrent Depression

Mindfulness-based Cognitive Therapy for Recurrent Depression Mindfulness-based Cognitive Therapy for Recurrent Depression Willem Kuyken Norwegian National Congress of Psychology Oslo, Norway 29 th August, 2013 Outline Background Does MBCT work? How does MBCT work?

More information

BILD Good Autism Practice Conference, 14 November, Birmingham Autism and happiness Peter Vermeulen, PhD Autisme Centraal

BILD Good Autism Practice Conference, 14 November, Birmingham Autism and happiness Peter Vermeulen, PhD Autisme Centraal Autism and happiness Peter Vermeulen, PhD Autisme Centraal www.autisme.be peter_autisme Outcome studies in autism Try to assess if and how people with autism succeed in adult life For recent review of

More information

in young people Management of depression in primary care Key recommendations: 1 Management

in young people Management of depression in primary care Key recommendations: 1 Management Management of depression in young people in primary care Key recommendations: 1 Management A young person with mild or moderate depression should typically be managed within primary care services A strength-based

More information

Oncology Nursing Society Annual Progress Report: 2008 Formula Grant

Oncology Nursing Society Annual Progress Report: 2008 Formula Grant Oncology Nursing Society Annual Progress Report: 2008 Formula Grant Reporting Period July 1, 2011 June 30, 2012 Formula Grant Overview The Oncology Nursing Society received $12,473 in formula funds for

More information

TREATING ASPD IN THE COMMUNITY: FURTHERING THE PD OFFENDER STRATEGY. Jessica Yakeley Portman Clinic Tavistock and Portman NHS Foundation Trust

TREATING ASPD IN THE COMMUNITY: FURTHERING THE PD OFFENDER STRATEGY. Jessica Yakeley Portman Clinic Tavistock and Portman NHS Foundation Trust TREATING ASPD IN THE COMMUNITY: FURTHERING THE PD OFFENDER STRATEGY Jessica Yakeley Portman Clinic Tavistock and Portman NHS Foundation Trust Treating the untreatable? Lack of evidence base for ASPD Only

More information

What happens to depressed adolescents? A beyondblue funded 3 9 year follow up study

What happens to depressed adolescents? A beyondblue funded 3 9 year follow up study What happens to depressed adolescents? A beyondblue funded 3 9 year follow up study Amanda Dudley, Bruce Tonge, Sarah Ford, Glenn Melvin, & Michael Gordon Centre for Developmental Psychiatry & Psychology

More information

Assessment of depression in adults in primary care

Assessment of depression in adults in primary care Assessment of depression in adults in primary care Adapted from: Identification of Common Mental Disorders and Management of Depression in Primary care. New Zealand Guidelines Group 1 The questions and

More information

Mechanisms of change in cognitive therapy and interpersonal therapy for depression: preliminary results from an ongoing trial

Mechanisms of change in cognitive therapy and interpersonal therapy for depression: preliminary results from an ongoing trial Mechanisms of change in cognitive therapy and interpersonal therapy for depression: preliminary results from an ongoing trial Marcus Huibers and Lotte Lemmens Department of Clinical Psychological Science,

More information

Depression Support Resources: Telephonic/Care Management Follow-up

Depression Support Resources: Telephonic/Care Management Follow-up Depression Support Resources: Telephonic/Care Management Follow-up Depression Support Resources: Telephonic/Care Management Follow-up Primary Care Toolkit September 2015 Page 29 Role of the Phone Clinician

More information

QUALITY ISSUES IN COMPLEX CONSULTATIONS : WHEN THE PATIENT IS A DOCTOR. Luc Lefebvre Arts in nood Antwerpen 10.12.2011

QUALITY ISSUES IN COMPLEX CONSULTATIONS : WHEN THE PATIENT IS A DOCTOR. Luc Lefebvre Arts in nood Antwerpen 10.12.2011 QUALITY ISSUES IN COMPLEX CONSULTATIONS : WHEN THE PATIENT IS A DOCTOR Luc Lefebvre Arts in nood Antwerpen 10.12.2011 Objectives 1) Acknowledge the complexity of the doctor-doctor consultation 2) Describe

More information

Hoofdstuk 2 Samenwerking en afstemming in de zorgketen

Hoofdstuk 2 Samenwerking en afstemming in de zorgketen Bijlage 3 Zoekstrategieën Hoofdstuk 2 Samenwerking en afstemming in de zorgketen Database Zoektermen 1 Premature Birth/ (2657) 2 exp infant, low birth weight/ or infant, premature/ (49701) 3 (((preterm

More information

Work and Mental Health: evidence from The Netherlands

Work and Mental Health: evidence from The Netherlands Work and Mental Health: evidence from The Netherlands 29 augustus 2008 Jac van der Klink, MD, PhD University Medical Center Groningen, Health Sciences, Public and Occupational Health Do adverse psychosocial

More information

Nalmefene for reducing alcohol consumption in people with alcohol dependence

Nalmefene for reducing alcohol consumption in people with alcohol dependence Nalmefene for reducing alcohol consumption in people with alcohol dependence Issued: November 2014 guidance.nice.org.uk/ta325 NICE has accredited the process used by the Centre for Health Technology Evaluation

More information

Collaborative care and psychiatric consultation models in primary care

Collaborative care and psychiatric consultation models in primary care Collaborative care and psychiatric consultation models in primary care C Van der Feltz-Cornelis Prof Primary Care Psychiatry Invitational Conference Nijmegen, 2 oktober 2013 Psychiatrist, Epidemiologist

More information

Depression, anxiety and long term conditions. Linda Gask Professor of Primary Care Psychiatry University of Manchester

Depression, anxiety and long term conditions. Linda Gask Professor of Primary Care Psychiatry University of Manchester Depression, anxiety and long term conditions Linda Gask Professor of Primary Care Psychiatry University of Manchester Depression and LTCs People with LTCs are twice as likely than other adults to suffer

More information

indicates that the relationship between psychosocial distress and disability in patients with CLBP is not uniform.

indicates that the relationship between psychosocial distress and disability in patients with CLBP is not uniform. Chronic low back pain (CLBP) is one of the most prevalent health problems in western societies. The prognosis of CLBP is poor, as indicated by very low rate of resolution, even with treatment. In CLBP,

More information

Bipolar Disorder: Advances in Psychotherapy

Bipolar Disorder: Advances in Psychotherapy Bipolar Disorder: Advances in Psychotherapy Questions from chapter 1 1) Which is characterized by one or more major depressive episodes with at least one hypomanic episode in which the patient s functioning

More information

Healthy Coping in Diabetes Self Management

Healthy Coping in Diabetes Self Management Healthy Coping in Diabetes Self Management Support for this product was provided by a grant from the Robert Wood Johnson Foundation in Princeton, New Jersey, 2009 Objectives Describe the relationship among

More information

Prepared by:jane Healey (Email: janie_healey@yahoo.com) 4 th year undergraduate occupational therapy student, University of Western Sydney

Prepared by:jane Healey (Email: janie_healey@yahoo.com) 4 th year undergraduate occupational therapy student, University of Western Sydney 1 There is fair (2b) level evidence that living skills training is effective at improving independence in food preparation, money management, personal possessions, and efficacy, in adults with persistent

More information

Randomized Controlled Trial to study the effectiveness of Lifestyle Triple P: a childhood obesity intervention aimed at parents of overweight children

Randomized Controlled Trial to study the effectiveness of Lifestyle Triple P: a childhood obesity intervention aimed at parents of overweight children Randomized Controlled Trial to study the effectiveness of Lifestyle Triple P: a childhood obesity intervention aimed at parents of overweight children S.M.P.L. Gerards 1, P.C. Dagnelie, M.W.J. Jansen,

More information

Algorithm for Initiating Antidepressant Therapy in Depression

Algorithm for Initiating Antidepressant Therapy in Depression Algorithm for Initiating Antidepressant Therapy in Depression Refer for psychotherapy if patient preference or add cognitive behavioural office skills to antidepressant medication Moderate to Severe depression

More information

Managing depression after stroke. Presented by Maree Hackett

Managing depression after stroke. Presented by Maree Hackett Managing depression after stroke Presented by Maree Hackett After stroke Physical changes We can see these Depression Emotionalism Anxiety Confusion Communication problems What is depression? Category

More information

Oncology Nursing Society Annual Progress Report: 2008 Formula Grant

Oncology Nursing Society Annual Progress Report: 2008 Formula Grant Oncology Nursing Society Annual Progress Report: 2008 Formula Grant Reporting Period July 1, 2009 June 30, 2010 Formula Grant Overview The Oncology Nursing Society received $12,473 in formula funds for

More information

Acceptance and Commitment Therapy (ACT) and Chronic Pain

Acceptance and Commitment Therapy (ACT) and Chronic Pain Acceptance and Commitment Therapy (ACT) and Chronic Pain Lance M. McCracken, PhD Centre for Pain Services Royal National Hospital for Rheumatic Diseases Centre for Pain Research University of Bath Bath

More information

Closer to real life: Using experience sampling method (ESM) in health care research

Closer to real life: Using experience sampling method (ESM) in health care research PIHET, Sandrine EICHER, Manuela Closer to real life: Using experience sampling method (ESM) in health care research SCHP BERNE 11-12.03.2014 12.03.2014 OVERVIEW 1. What is ESM? 2. Domains of application

More information

information for families Schizophrenia & Substance Use

information for families Schizophrenia & Substance Use information for families Schizophrenia & Substance Use Schizophrenia and Substance Use Index 2 3 5 6 7 8 9 10 Why do people with schizophrenia use drugs and alcohol? What is the impact of using substances

More information

DEPRESSION Depression Assessment PHQ-9 Screening tool Depression treatment Treatment flow chart Medications Patient Resource

DEPRESSION Depression Assessment PHQ-9 Screening tool Depression treatment Treatment flow chart Medications Patient Resource E-Resource March, 2015 DEPRESSION Depression Assessment PHQ-9 Screening tool Depression treatment Treatment flow chart Medications Patient Resource Depression affects approximately 20% of the general population

More information

Database of randomized trials of psychotherapy for adult depression

Database of randomized trials of psychotherapy for adult depression Database of randomized trials of psychotherapy for adult depression In this document you find information about the database of 352 randomized controlled trials on psychotherapy for adult depression. This

More information

SAFE BUT SORRY. Theory, assesment, and treatment of pain-related fear in chronic low back pain patients

SAFE BUT SORRY. Theory, assesment, and treatment of pain-related fear in chronic low back pain patients SAFE BUT SORRY Theory, assesment, and treatment of pain-related fear in chronic low back pain patients SAFE but SORRY: Theory, assessment, and treatment of pain-related fear in chronic low back pain patients

More information

Screening and treatment to prevent depression in retirees (age over 65 years)

Screening and treatment to prevent depression in retirees (age over 65 years) Screening and treatment to prevent depression in retirees (age over 65 years) Matrix Insight, in collaboration with Imperial College London, Kings College London and Bazian Ltd, were commissioned by Health

More information

Mental Health Needs Assessment Personality Disorder Prevalence and models of care

Mental Health Needs Assessment Personality Disorder Prevalence and models of care Mental Health Needs Assessment Personality Disorder Prevalence and models of care Introduction and definitions Personality disorders are a complex group of conditions identified through how an individual

More information

8.2 COMPUTERISED COGNITIVE BEHAVIOURAL THERAPY WITH ONLINE DISCUSSION GROUP

8.2 COMPUTERISED COGNITIVE BEHAVIOURAL THERAPY WITH ONLINE DISCUSSION GROUP 8 EATING DISORDERS 8.1 INTRODUCTION The eating disorders include anorexia nervosa, bulimia nervosa, binge eating disorder as well as variants of these states. With the exception of binge eating disorder,

More information

For further information or to schedule appointment, please contact Day Program Intake Clinician on 8416 3800.

For further information or to schedule appointment, please contact Day Program Intake Clinician on 8416 3800. Day Programs General Information Day Programs at the Melbourne Clinic (TMC) offer therapy treatment to people with a range of psychiatric conditions. The programs are evidence based and are facilitated

More information

Major Depressive Disorder (MDD) Guideline Diagnostic Nomenclature for Clinical Depressive Conditions

Major Depressive Disorder (MDD) Guideline Diagnostic Nomenclature for Clinical Depressive Conditions Major Depressive Disorder Major Depressive Disorder (MDD) Guideline Diagnostic omenclature for Clinical Depressive Conditions Conditions Diagnostic Criteria Duration Major Depression 5 of the following

More information

Depressive Disorders Inpatient Management v.1.1

Depressive Disorders Inpatient Management v.1.1 Depressive Disorders Inpatient Management v.1.1 Executive Summary Citation Information Explanation of Evidence Ratings Summary of Version Changes Intake Admission interview, physical exam, and review of

More information

Early Response Concussion Recovery

Early Response Concussion Recovery Early Response Concussion Recovery KRISTA MAILEY, BSW RSW, CONCUSSION RECOVERY CONSULTANT CAREY MINTZ, PH.D., C. PSYCH., PRACTICE IN CLINICAL NEUROPSYCHOLOGY FOR REFERRAL: Contact Krista Mailey at (204)

More information

Australian Mental Health Outcomes and Classification Network. Mental Health Inventory

Australian Mental Health Outcomes and Classification Network. Mental Health Inventory Australian Mental Health Outcomes and Classification Network Mental Health Inventory Training Manual A joint Australian, State and Territory Government Initiative Commonwealth of Australia 2005 This work

More information

UK Society for Behavioural Medicine 9 th Annual Scientific Meeting

UK Society for Behavioural Medicine 9 th Annual Scientific Meeting UK Society for Behavioural Medicine 9 th Annual Scientific Meeting Behavioural Medicine: From Laboratory to Policy University of Oxford Examination Schools Monday 9 and Tuesday 10 December 2013 NPRI UK

More information

THE DEPRESSION RESEARCH CLINIC Department of Psychiatry and Behavioral Sciences Stanford University, School of Medicine

THE DEPRESSION RESEARCH CLINIC Department of Psychiatry and Behavioral Sciences Stanford University, School of Medicine THE DEPRESSION RESEARCH CLINIC Department of Psychiatry and Behavioral Sciences Stanford University, School of Medicine Volume 1, Issue 1 August 2007 The Depression Research Clinic at Stanford University

More information

How to manage Business Apps - Case for a Mobile Access Strategy -

How to manage Business Apps - Case for a Mobile Access Strategy - How to manage Business Apps - Case for a Mobile Access Strategy - Hans Heising, Product Manager Gábor Vida, Manager Software Development RAM Mobile Data 2011 Content Introduction 2 Bring your own device

More information

Identification and Treatment Manual

Identification and Treatment Manual Therapeutic Identification of Depression in Young People Identification and Treatment Manual The TIDY project The Academic Unit of Child and Adolescent Psychiatry, Imperial College London & Lonsdale Medical

More information

Kansen in KP7 NMP. Aansluitend op de HTSM Roadmap Nanotechnologie. 11 juni 2012. Melvin A. Kasanrokijat

Kansen in KP7 NMP. Aansluitend op de HTSM Roadmap Nanotechnologie. 11 juni 2012. Melvin A. Kasanrokijat Kansen in KP7 NMP Aansluitend op de HTSM Roadmap Nanotechnologie 11 juni 2012 Melvin A. Kasanrokijat Mogelijkheden in KP7 - Cooperation Groot programma met 10 verschillende thema s NMP, ICT, Health, Energy,

More information

Mindfulness for Anxiety, Depression & Wellness

Mindfulness for Anxiety, Depression & Wellness Mindfulness for Anxiety, Depression & Wellness Carl Fulwiler Center for Mental Health Services Research Department of Psychiatry UMass Medical School Public Sector Conference June 16, 2011 Meta-analysis:

More information

Psychological Well-being of Women With Metastatic Breast. Innovative a Community Supportive-Expressive Group in a Community Setting

Psychological Well-being of Women With Metastatic Breast. Innovative a Community Supportive-Expressive Group in a Community Setting Psychological Well-being of Women With Metastatic Breast Psychological Cancer in Well-being an Innovative of Women with Supportive-expressive Metastatic Breast Cancer Group in in an Innovative a Community

More information

Patiënten met Onverklaarde Lichamelijke Klachten: Aanzet tot een persoonlijkheidsprofiel

Patiënten met Onverklaarde Lichamelijke Klachten: Aanzet tot een persoonlijkheidsprofiel Patiënten met Onverklaarde Lichamelijke Klachten: Aanzet tot een persoonlijkheidsprofiel Evelien Inghels, psycholoog, Twee Steden Ziekenhuis Gerrit Delfstra, klinisch psycholoog, GGZ Oost Brabant en werkgroep

More information

Do Patients of Racial/Ethnic Minority and Lower SES Use Depression Care Management Differently?

Do Patients of Racial/Ethnic Minority and Lower SES Use Depression Care Management Differently? Do Patients of Racial/Ethnic Minority and Lower SES Use Depression Care Management Differently? Yuhua Bao, Ph.D. Division of Health Policy, Department of Public Health Weill Cornell Medical College 2009

More information

RIJKSUNIVERSITEIT GRONINGEN BOTTOM-UP REHABILITATION IN SCHIZOPHRENIA

RIJKSUNIVERSITEIT GRONINGEN BOTTOM-UP REHABILITATION IN SCHIZOPHRENIA RIJKSUNIVERSITEIT GRONINGEN BOTTOM-UP REHABILITATION IN SCHIZOPHRENIA Proefschrift ter verkrijging van het doctoraat in de Geneeskunde aan de Rijksuniversiteit Groningen op gezag van de Rector Magnificus

More information

Changes in Pilot Control Behaviour across Stewart Platform Motion Systems

Changes in Pilot Control Behaviour across Stewart Platform Motion Systems Changes in Pilot Control Behaviour across Stewart Platform Motion Systems PROEFSCHRIFT ter verkrijging van de graad van doctor aan de Technische Universiteit Delft, op gezag van de Rector Magnificus prof.

More information

Division of Child and Family Services Treatment Plan Goal Status Review Aggregate Report

Division of Child and Family Services Treatment Plan Goal Status Review Aggregate Report I. Introduction Division of Child and Family Services Treatment Plan Goal Status Review Aggregate Report The more efficient and effective the delivery of our services, the greater our opportunity for realizing

More information

Suicidal. Caring For The Person Who Is. Why might a person be suicidal?

Suicidal. Caring For The Person Who Is. Why might a person be suicidal? Caring For The Person Who Is Suicidal For further information see also the following MIND Essentials resource Conducting a suicide risk assessment. Suicidal thoughts and behaviours are not unique to mental

More information

Parent-Child Relationships in Early Childhood and Development of Anxiety & Depression

Parent-Child Relationships in Early Childhood and Development of Anxiety & Depression Parent-Child Relationships in Early Childhood and Development of Anxiety & Depression JENNIFER L. HUDSON, PhD Centre for Emotional Health, Department of Psychology, Macquarie University, AUSTRALIA Topic

More information

Glossary of Methodologic Terms

Glossary of Methodologic Terms Glossary of Methodologic Terms Before-After Trial: Investigation of therapeutic alternatives in which individuals of 1 period and under a single treatment are compared with individuals at a subsequent

More information

Pennsylvania Depression Quality Improvement Collaborative

Pennsylvania Depression Quality Improvement Collaborative Pennsylvania Depression Quality Improvement Collaborative Carol Hann, RN, MSN, CPHQ, Collaborative Manager Southeastern Pennsylvania Association for Healthcare Quality (SPAHQ) David Payne, Psy.D., Senior

More information

What works for bipolar disorder and how should this be delivered in practice?

What works for bipolar disorder and how should this be delivered in practice? What works for bipolar disorder and how should this be delivered in practice? Daniel Smith daniel.smith@glasgow.ac.uk W4 Improving the diagnosis and management of bipolar disorder: screening, integrated

More information

Mental Health Smartphone Application A New Initiative for Mental Health Care Providers

Mental Health Smartphone Application A New Initiative for Mental Health Care Providers Mental Health Smartphone Application A New Initiative for Mental Health Care Providers Dr. Melvyn Zhang MBBS (S pore), DCP(Ireland), MRCPsych(UK) Psychiatry Resident in Training Department of Psychological

More information

Is it time for a new drug development paradigm?

Is it time for a new drug development paradigm? Is it time for a new drug development paradigm? Robert McDonough, M.D. Senior Director, Clinical Policy Research and Development 1 The Aetna Way Our Cause To make quality health care more affordable and

More information

Fixing Mental Health Care in America

Fixing Mental Health Care in America Fixing Mental Health Care in America A National Call for Measurement Based Care in Behavioral Health and Primary Care An Issue Brief Released by The Kennedy Forum Prepared by: John Fortney PhD, Rebecca

More information

Treatment of Mixed Anxiety-Depression Disorder: Long-Term Outcome

Treatment of Mixed Anxiety-Depression Disorder: Long-Term Outcome Behavioural and Cognitive Psychotherapy, 2006, 34, 95 101 Printed in the United Kingdom doi:10.1017/s1352465805002511 Treatment of Mixed Anxiety-Depression Disorder: Long-Term Outcome Enrique Echeburúa,

More information

Motoriek, cognitie en gedrag bij ouderen met een dementie

Motoriek, cognitie en gedrag bij ouderen met een dementie Motoriek, cognitie en gedrag bij ouderen met een dementie Erik Scherder Afdeling Klinische Neuropsychologie, VU Amsterdam 1 PFC ACC Str H SN Crbl 2 Effects of aerobic exise on overweight children's cognitive

More information

Effects of a 12-Week Mindfulness, Compassion and Loving Kindness Program on Chronic Depression: A Pilot Within-Subjects-Waitlist- Controlled Trial

Effects of a 12-Week Mindfulness, Compassion and Loving Kindness Program on Chronic Depression: A Pilot Within-Subjects-Waitlist- Controlled Trial Effects of a 12-Week Mindfulness, Compassion and Loving Kindness Program on Chronic Depression: A Pilot Within-Subjects-Waitlist- Controlled Trial Johannes Graser, Volkmar Höfling, Charlotte Weßlau, Adriana

More information

Applying ACT to Cases of Complex Depression: New Clinical and Research Perspectives

Applying ACT to Cases of Complex Depression: New Clinical and Research Perspectives Applying ACT to Cases of Complex Depression: New Clinical and Research Perspectives Part I: Depression with Psychosis and Suicidality Brandon Gaudiano, Ph.D. Assistant Professor of Psychiatry Grant Support:

More information

Brisbane Centre for Post Natal Disorders. Patient information brochure

Brisbane Centre for Post Natal Disorders. Patient information brochure Brisbane Centre for Post Natal Disorders Patient information brochure What is a Post Natal Disorder? A Post Natal Disorder may occur any time during the first two years after birth, or it may occur before

More information

Applied Behavior Analysis for Autism Spectrum Disorders

Applied Behavior Analysis for Autism Spectrum Disorders Applied Behavior Analysis for Autism Spectrum Disorders I. Policy University Health Alliance (UHA) will reimburse for Applied Behavioral Analysis (ABA), as required in relevant State of Hawaii mandates,

More information

FRN Research Report March 2011: Correlation between Patient Relapse and Mental Illness Post-Treatment

FRN Research Report March 2011: Correlation between Patient Relapse and Mental Illness Post-Treatment FRN Research Report March 2011: Correlation between Patient Relapse and Mental Illness Post-Treatment Background Studies show that more than 50% of patients who have been diagnosed with substance abuse

More information

Good Practice, Evidence Base and Implementation Issues: Personality Disorder. Prof Anthony W Bateman SMI Stake Holder Event

Good Practice, Evidence Base and Implementation Issues: Personality Disorder. Prof Anthony W Bateman SMI Stake Holder Event Good Practice, Evidence Base and Implementation Issues: Personality Disorder Prof Anthony W Bateman SMI Stake Holder Event Treatment for Borderline Personality Disorder A range of structured treatment

More information

The influence of psychodynamic psychotherapy on depressive symptoms a follow up study.

The influence of psychodynamic psychotherapy on depressive symptoms a follow up study. The influence of psychodynamic psychotherapy on depressive symptoms a follow up study. Krzysztof Małyszczak, Tomasz Pawłowski, Adrian Sieradzki, Krystian Pyszel, Przemysław Pacan, Andrzej Kiejna Summary

More information

EFFICACY OF EYE MOVEMENT DESENSITIZATION TREATMENT THROUGH THE INTERNET ABSTRACT

EFFICACY OF EYE MOVEMENT DESENSITIZATION TREATMENT THROUGH THE INTERNET ABSTRACT EFFICACY OF EYE MOVEMENT DESENSITIZATION TREATMENT THROUGH THE INTERNET Keiko Nakano Department of Clinical Psychology/Atomi University JAPAN ABSTRACT The effectiveness of an internet based eye movement

More information

The Counselling and Wellness Centre at MDABC

The Counselling and Wellness Centre at MDABC The Counselling and Wellness Centre at MDABC Winter 2016 Program Guide Learn to improve your MOOD and live a more BALANCED LIFE. The non-profit Counselling and Wellness Centre at MDABC offers private counselling

More information

Indiana Association for Infant and Toddler Mental Health DC 0-3 R Crosswalk to DSM and ICD Systems

Indiana Association for Infant and Toddler Mental Health DC 0-3 R Crosswalk to DSM and ICD Systems Indiana Association for Infant and Toddler Mental Health DC 0-3 R Crosswalk to DSM and ICD Systems Although the benefits of early identification and treatment of developmental and behavioral problems are

More information

Copyright 2015 VMdamentals.com. All rights reserved.

Copyright 2015 VMdamentals.com. All rights reserved. Copyright 2015. All rights reserved. Copyright 2015. All rights reserved. The S oftware Erik Zandboer Advisory vspecialist EMC 2 Europe West D efined D ata C enter Copyright 2015. All rights reserved.

More information

Michelle D. Sherman, Ph.D.

Michelle D. Sherman, Ph.D. Michelle D. Sherman, Ph.D. Director, OKC VAMC Family Mental Health Program Clinical Professor, University of Oklahoma Health Sciences Center, Core Investigator, South Central MIRECC Overview 1. Rationale

More information

De Positieve Psychologie van Arbeid en Gezondheid

De Positieve Psychologie van Arbeid en Gezondheid De Positieve Psychologie van Arbeid en Gezondheid Prof. dr. Arnold Bakker www.arnoldbakker.com Symposium Alles Goed? 3 februari 2011 PART 1 The Concept Positive Organizational Behavior The study and application

More information

PAPEL DE LA PSICOTERAPIA EN EL TRATAMIENTO DEL TRASTORNO BIPOLAR

PAPEL DE LA PSICOTERAPIA EN EL TRATAMIENTO DEL TRASTORNO BIPOLAR PAPEL DE LA PSICOTERAPIA EN EL TRATAMIENTO DEL TRASTORNO BIPOLAR Dr. Francesc Colom PsyD, MSc, PhD Bipolar Disorders Program IDIBAPS- CIBERSAM -Hospital Clínic Barcelona, University of Barcelona Centro

More information

The Effect of Physical Exercise on Depression; Case study: Professional and Nonprofessional

The Effect of Physical Exercise on Depression; Case study: Professional and Nonprofessional Available online athttp://www.ijashss.com International Journal of Advanced Studies in Humanities and Social Science Volume 1, Issue 8, 2013: 1161-1165 The Effect of Physical Exercise on Depression; Case

More information

Treatment Interventions for Suicide Prevention. Kate Comtois, PhD, MPH University of Washington

Treatment Interventions for Suicide Prevention. Kate Comtois, PhD, MPH University of Washington Treatment Interventions for Suicide Prevention Kate Comtois, PhD, MPH University of Washington Suicide prevention has many forms Treating Depression Gatekeeper Training Public health or injury prevention

More information

Family Focused Therapy for Bipolar Disorder (Clinical Case Series) Participant Information Sheet

Family Focused Therapy for Bipolar Disorder (Clinical Case Series) Participant Information Sheet Family Focused Therapy for Bipolar Disorder (Clinical Case Series) Participant Information Sheet Study Title: Family Focused Therapy for Bipolar Disorder: A Clinical Case Series) We would like to invite

More information

Mindfulness Interventions for Adolescents

Mindfulness Interventions for Adolescents Research Module Assignment 1: A critical appraisal of research studies into mindfulness-based interventions in an area of your choice; if appropriate, contextualise this within the wider evidence base

More information

Psychopathology. Stages of research. Interventions

Psychopathology. Stages of research. Interventions Psychopathology Change in the way look at problems. Similar to change in biology. Also look over life cycle. Look at how they adapt to change. 1 Burden Stages of research Diagnosable symptomatology Positive

More information

PSYCHOSOCIAL FUNCTIONING IN PATIENTS WITH PERSONALITY DISORDERS: A REVIEW OF THE EVIDENCE-BASED RESEARCH STUDIES LITERATURE

PSYCHOSOCIAL FUNCTIONING IN PATIENTS WITH PERSONALITY DISORDERS: A REVIEW OF THE EVIDENCE-BASED RESEARCH STUDIES LITERATURE PSYCHOSOCIAL FUNCTIONING IN PATIENTS WITH PERSONALITY DISORDERS: A REVIEW OF THE EVIDENCE-BASED RESEARCH STUDIES LITERATURE Wendy Dávila Wood, Aizpea Boyra and José Guimón onpguugj@ehu.es SUMMARY Evidence

More information

Network Analysis: Lecture 1. Sacha Epskamp 02-09-2014

Network Analysis: Lecture 1. Sacha Epskamp 02-09-2014 : Lecture 1 University of Amsterdam Department of Psychological Methods 02-09-2014 Who are you? What is your specialization? Why are you here? Are you familiar with the network perspective? How familiar

More information

Courses Description Bachelor Degree in Social Work

Courses Description Bachelor Degree in Social Work Courses Description Bachelor Degree in Social Work Introduction to Social Work 2701101 Understanding the history of social work profession. Other topics include the philosophy, principles and ethics of

More information

Designing Clinical Addiction Research

Designing Clinical Addiction Research Designing Clinical Addiction Research Richard Saitz MD, MPH, FACP, FASAM Professor of Medicine & Epidemiology Boston University Schools of Medicine & Public Health Director, Clinical Addiction, Research

More information

Generalist working with youth and families in the Netherlands

Generalist working with youth and families in the Netherlands Generalist working with youth and families in the Netherlands Pink Hilverdink October 2013 Introduction From 2015 onwards the Dutch child welfare system will be fully decentralized and reformed. Dutch

More information

ASD, ABA and Impact on Caregiver Burden. Erin Nolan & Fletcher Wood

ASD, ABA and Impact on Caregiver Burden. Erin Nolan & Fletcher Wood ASD, ABA and Impact on Caregiver Burden Erin Nolan & Fletcher Wood Family Match ALEX, 6 Max, 6 Background Family Match Growing numbers of children identified with autism (suggested 1 in 50 by CDC). ABA

More information

Regence. Section: Mental Health Last Reviewed Date: January 2013. Policy No: 18 Effective Date: March 1, 2013

Regence. Section: Mental Health Last Reviewed Date: January 2013. Policy No: 18 Effective Date: March 1, 2013 Regence Medical Policy Manual Topic: Applied Behavior Analysis for the Treatment of Autism Spectrum Disorders Date of Origin: January 2012 Section: Mental Health Last Reviewed Date: January 2013 Policy

More information

HTA Position Paper. The International Network of Agencies for Health Technology Assessment (INAHTA) defines HTA as:

HTA Position Paper. The International Network of Agencies for Health Technology Assessment (INAHTA) defines HTA as: HTA Position Paper The Global Medical Technology Alliance (GMTA) represents medical technology associations whose members supply over 85 percent of the medical devices and diagnostics purchased annually

More information

Form B-1. Inclusion form for the effectiveness of different methods of toilet training for bowel and bladder control

Form B-1. Inclusion form for the effectiveness of different methods of toilet training for bowel and bladder control Form B-1. Inclusion form for the effectiveness of different methods of toilet training for bowel and bladder control Form B-2. Assessment of methodology for non-randomized controlled trials for the effectiveness

More information

Personalised Psychiatry Depression. Amsterdamse school 31012014. Aartjan TF Beekman Dpt Psychiatry VUmc & GGZinGeest Amsterdam

Personalised Psychiatry Depression. Amsterdamse school 31012014. Aartjan TF Beekman Dpt Psychiatry VUmc & GGZinGeest Amsterdam Personalised Psychiatry Depression Amsterdamse school 31012014 Aartjan TF Beekman Dpt Psychiatry VUmc & GGZinGeest Amsterdam Disclosure Informatie Beekman Onderzoek: Eli Lilly, Astra Zeneca, Jansen, Shire

More information

Mobile: +31 6 48 26 19 29 1

Mobile: +31 6 48 26 19 29 1 , Roadmap 1 Social-economic developments.over de weg naar duurzame en goede zorg een beschouwing vanuit internationaal maatschappelijk-economisch perspectief NEVI zorgcongres 05-02-2015 2 Healthcare paradigm

More information

Improving the Measurement Properties of Depressive Symptom Instruments for Use after SCI

Improving the Measurement Properties of Depressive Symptom Instruments for Use after SCI Improving the Measurement Properties of Depressive Symptom Instruments for Use after SCI Allen Heinemann, PhD Ryan Williams, PhD Charles Bombardier, PhD Martin Forchheimer, MPP Jesse Fann, MD Holly Neumann,

More information

Self-management strategies for mild to moderate depression

Self-management strategies for mild to moderate depression Department of Epidemiology & Public Health Lunchtime seminar, 18 th Feb 2014 Self-management strategies for mild to moderate depression The internet-based ifightdepression tool Dr Celine Larkin National

More information

LEERSTIJLEN EN STUREN VAN LEERPROCESSEN IN HET HOGER ONDERWIJS. Naar procesgerichte instructie in zelfstandig denken

LEERSTIJLEN EN STUREN VAN LEERPROCESSEN IN HET HOGER ONDERWIJS. Naar procesgerichte instructie in zelfstandig denken LEERSTIJLEN EN STUREN VAN LEERPROCESSEN IN HET HOGER ONDERWIJS Naar procesgerichte instructie in zelfstandig denken PROEFSCHRIFT ter verkrijging van de graad van doctor aan de Katholieke Universiteit Brabant,

More information

Use of the Ohio Consumer Outcomes Initiative to Facilitate Recovery: Empowerment and Symptom Distress

Use of the Ohio Consumer Outcomes Initiative to Facilitate Recovery: Empowerment and Symptom Distress Use of the Ohio Consumer Outcomes Initiative to Facilitate Recovery: Empowerment and Symptom Distress Erik Stewart, Ph.D Reneé Kopache, MS ABSTRACT: In 1996, Ohio set forth on a path to further enhance

More information

2019 Healthcare That Works for All

2019 Healthcare That Works for All 2019 Healthcare That Works for All This paper is one of a series describing what a decade of successful change in healthcare could look like in 2019. Each paper focuses on one aspect of healthcare. To

More information