A Texas Life Science Perspective. Thomas R. Kowalski President Texas Healthcare and Bioscience Institute

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1 A Texas Life Science Perspective Thomas R. Kowalski President Texas Healthcare and Bioscience Institute 1

2 What is THBI? The Texas Healthcare and Bioscience Institute (THBI) is a non-profit, public policy research organization, comprised of biotechnology, medical device, and pharmaceutical companies, economic development entities, academic, and private research institutions, as well as companies that provide goods and services to core organizations. 2

3 THBI Mission Statement The mission of the Texas Healthcare and Bioscience Institute is to research, develop, and advocate policies and actions that promote biomedical science, biotechnology, agriculture, and medical device innovation in Texas. 3

4 Defining the Biosciences The biosciences are a diverse group of industries and activities with a common link-they apply knowledge of the way in which plants, animals, and humans function. The sector spans different markets and includes manufacturing, services, and research activities. By definition, the biosciences are a unique industry cluster and are constantly growing and changing to incorporate the latest research and scientific discoveries. Source: BIO 4

5 The Life Science Innovation Lifecycle Knowledge Creation Universities and Research Institutions Federal R&D Regulatory Environment Licenses Patents Proof of Concept Testing Conception Incubation/ Research Parks Formation Venture Capital Clinical Trials Technology Transfer Collaborations/ Partnerships Regulatory Approval Industry Consortia And Partnerships Maturity Growth Business Planning Industry R&D Job Creation M&A Activity IPOs/Gazelles Product Pipeline Clusters and Networks Economics of Scale Value-add Labor Market/ Graduates Commercialization 5

6 Key Best Practice Factors in Building a Biosciencedriven Economy Ingredients for building a critical mass in the biosciences in states and regions include: n Engaged universities with active leadership n Building entrepreneurial cultures with intensive networking across sectors and with industry n Available capital covering all stages of business cycle n Discretionary federal or other R&D funding n Workforce and talent pool n Access to specialized facilities and equipment n Supportive business, tax and regulatory policies n Patience and a long-term perspective 6

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8 Texas Legislative Sessions Texas Emerging Technology Fund (79 th ) Has allocated $194 million in funds to 136 early stage companies Has allocated over $194 million in grant matching and research superiority funds to Texas Universities $592 Million in additional follow-on investments Texas Enterprise Fund (78 th ) The TEF has awarded $98.1million for biotechnology related projects, creating 11,451 jobs Pharmaceutical Biotech Cleanroom Exemption (80 th ) Texas Cancer Prevention and Research Institute of Texas (80 th ) $3B - $300MM per year for 10 years/to date, 429 awards worth $760 MM for cancer research, commercialization and prevention Texas Tier One Initiative $500MM Product Development Fund $45 MM 8

9 Texas Enterprise Fund 9

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11 Emerging Technology Fund 11

12 Texas Regional Centers of Innovation and Commercialization 12

13 Economic Impact of Life Sciences on Texas The Life Sciences industry generates a significant economic impact on the state of Texas, as companies and institutions purchase equipment and inputs and well paid employees spend money in their home communities. The industry s total economic impact on the State of Texas is estimated at $75 billion in economic activity, 236,000 jobs, and $31 billion in payroll. State and local governments receive an estimated $2 billion each year due to these impacts. 13

14 Direct and Indirect Impacts of Life Sciences in Texas 14

15 Texas Healthcare and Bioscience Institute 815 Brazos Street Suite 310 Austin, Texas