Clarithromycin - MATERIAL SAFETY DATA SHEET
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1 Clarithromycin - MATERIAL SAFETY DATA SHEET Version 2.0 Revision Date 09/01/ SUBSTANCE IDENTITY AND COMPANY CONTACT INFORMATION Product Name Product Number Procedure Brand Company Clarithromycin C033 Clarithromycin TOKU-E 715 W. Orchard Drive Suite 3 Bellingham, WA EMERGENCY PHONE (US only) INF CHEMICAL COMPOSITION AND DATA ON COMPONENTS CAS NO Formula C 38 H 69 NO 13 Molecular Weight HAZARD IDENTIFICATION Hazard description This product contains no hazardous constituents, or the concentrations of all chemical constituents are below the regulatory threshold limits described by Occupational Safety Health Administration Hazard Communication Standard 29 CFR and the European Directive 91/155/EEC, and 93/112/EC. Classification system the classification was made according to the latest editions of international substances lists, and expanded upon from company and literature data. 4. FIRST-AID MEASURES 1 / 6
2 In case of eye and skin contact Immediately flush eyes or skin with copious amounts of water at least 15minutes while removing contaminated clothing and shoes. Assure adequate flushing of eyes by separating eyelids with fingers. If inhaled Remove to fresh air. If breathing is difficult, call a physician. If swallowed Wash out mouth with water (provided person is conscious). Call a physician immediately. Others Wash all contaminated clothing before reuse. 5. FIRE-FIGHTING MEASURES Suitable extinguishing media Suitable extinguishing agents CO 2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam Protective equipment No special measures required. 6. ACCIDENTAL RELEASE MEASURES Personal precautions Not required. Measures for environmental protection Wipe up with damp sponge or mop. Measures for cleaning/ collecting No special measures required. Additional information No dangerous substances are released. 7. HANDLING AND STORAGE Handling Keep receptacles tightly sealed. Information about protection against explosions and fires: No special measures required. Storage Requirements to be met by storerooms and receptacles: No special requirements. Information about storage in one common storage facility: Store away from oxidizing agents. Further information about storage conditions: Store in cool, dry conditions in well sealed containers. 2 / 6
3 8. EXPOSURE CONTROLS AND PERSONAL PROTECTION Contains no substances with occupational exposure limit values. Personal protective equipment Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a dust mask type N95 (US) or type P1 (EN 143) respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Hand protection Handle with gloves. For prolonged or repeated contact use protective gloves. Eye protection Safety glasses with side-shields conforming to EN166 Skin and body protection Choose body protection according to the amount and concentration of the dangerous substance at the work place. Hygiene measures Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance ph Melting point Solubility White Solid N/A N/A N/A 10. STABILITY AND REACTIVITY Chemical stability Stable under recommended storage conditions. Conditions to avoid Materials to avoid Strong oxidizing agents 3 / 6
4 Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides, nitrogen oxides (NOx). 11. TOXICOLOGICAL INFORMATION Potential Health Effects Inhalation Skin Eyes Ingestion Target Organs May be harmful if inhaled. May cause respiratory tract irritation. May be harmful if absorbed through skin. May cause skin irritation. May cause eye irritation. Harmful if swallowed. Teeth, Bones. Signs and Symptoms of Exposure To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. Acute toxicity LD50 Oral - rat 1,270 mg/kg Remarks: Behavioral: Change in motor activity (specific assay). Skin corrosion/irritation Serious eye damage/eye irritation Respiratory or skin sensitization Germ cell mutagenicity Carcinogenicity IARC ACGIH NTP OSHA identified as probable, possible or confirmed human carcinogen by IARC. identified as a carcinogen or potential carcinogen by ACGIH. identified as a known or anticipated carcinogen by NTP. 4 / 6
5 identified as a carcinogen or potential carcinogen by OSHA. Reproductive toxicity Specific target organ toxicity - single exposure (GHS) Specific target organ toxicity - repeated exposure (GHS) Aspiration hazard 12. ECOLOGICAL INFORMATION Data not yet available. 13. DISPOSAL CONSIDERATIONS Product Observe all federal, state, and local environmental regulations. Contaminated packaging Dispose of as unused product. 14. TRANSPORT INFORMATION DOT (US) IMDG IATA Not dangerous goods Not dangerous goods Not dangerous goods 15. REGULATORY INFORMATION OSHA Hazards Harmful by ingestion. DSL Status This product contains the following components that are not on the Canadian DSL nor NDSL lists. SARA 302 Components 5 / 6
6 SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302. SARA 313 Components SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313. SARA 311/312 Hazards Acute Health Hazard Massachusetts Right To Know Components No components are subject to the Massachusetts Right to Know Act. Pennsylvania Right To Know Components New Jersey Right To Know Components California Prop. 65 Components WARNING! This product contains a chemical known to the State of California to cause birth defects or other reproductive harm. 16. OTHER INFORMATION Further information The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Toku-e Co., shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale. 6 / 6
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