P R O D U C T L I S T

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1 PRODUTLIST

2 HALTH-FOOD INRDINTS DISLAIMRS PHARMAUTIAL HALTH - FOOD PRSONAL AR FOOD & FLAVOURS Please note this documentation is available for various countries all over the world and hence it may contain statements or product classification not applicable to your country. The claims made are in reference to ingredients only, hence they do not refer to finished products and they may not comply with Regulation n. 1924/2006. The marketer of any finished product containing any ingredient is responsible for assuring that the destination of the product and the claims made for the finished product are lawful and comply with all applicable laws and regulations of the country or countries in which the product is to be sold. The ingredients described herein are offered for consideration for use in healthfood, pharmaceuticals and personal care. TH QUALITY compliance with cmps and in pharmaceutical inspected suites, supported by TD-DMFs. under Hazard Analysis and rytical ontrol Points (HAP) Indena s Personal are ingredients are RAH registered Botanical extracts with organoleptic properties RAS: ORT KOSHR P PRSONAL AR INRDINTS DISLAIMR The ingredients described herein are offered for consideration for use in personal care products. The information provided describes historical use, ingredient activity and other information that may be relevant to their use in such products. How each ingredient would contribute to a particular product would be formulation specific. Furthermore please note that this documentation is available for various countries all over the world and hence it may contain statements not applicable to your country. OUR MISSION At Indena we believe that an in-depth knowledge in active ingredients derived from botanicals and the search for excellence at all times are crucial commitments to serving our customers in pharmaceuticals, health-foods, foods and personal care. Research and production technologies are the main focus of our mission and the way we create a value difference for our partners. And we ve got more than 90 years of experience to prove it. xcellence in botanical derivatives

3 06 ISOLATD or SMISYNTHTI PUR PRODUTS PUR MOLULS ISOLATD OR DRIVD FROM PLANTS 10 STANDARDIZD, PURIFID or OTHR HARATRIZD DRY XTRATS DRY XTRATS WITH RPRODUIBL ONTNT OF HARATRISTI PRINIPLS INDNA RSARHS, DVLOPS and MARKTS ATIV PRINIPLS and INRDINTS DRIVD FROM DIBL and MDIINAL PLANTS 22 HARATRIZD, STANDARDIZD OILY and SOFT XTRATS OILY / SOFT XTRATS WITH RPRODUIBL ONTNT OF HARATRISTI PRINIPLS 24 PHYTOSOM MOR BIOAVAILABL FORMS OF ATIV PRINIPLS 28 FOOD & FLAVOURS BOTANIAL XTRATS WITH ORANOLPTI PROPRTIS PHYTOSOM IS A RISTRD TRADMARK

4 ISOLATD or SMISYNTHTI PUR PRODUTS PUR MOLULS ISOLATD OR DRIVD FROM PLANTS BRAND - NLISH NAM BOTANIAL ORIIN ASSAY BIOLOIAL ATIVITY AJMALIN Rauvolfia vomitoria Afz. - Root bark 98.0% 102.0% by HPL Antiarrhythmic ASIATIOSID entella asiatica (L.) Urban - Leaf 85.0% of asiaticoside by HPL Anti-wrinkles, Lips care BOLDIN Peumus boldus Molina - Bark 98.5% 100.5% by potentiometry holeretic NTROX - HTROSIDS entella asiatica (L.) Urban - Leaf 50.0% 70.0% of madecassoside and terminoloside, 10.0% 20.0% of asiaticoside, 70.0% 90.0% of sum of madecassoside, terminoloside and asiaticoside by HPL OLHIIN PH. UR. loriosa superba L. - Seed 97.0% 102.0% by potentiometry Antigout OLHIIN USP loriosa superba L. - Seed 94.0% 101.0% by HPL Antigout OLHIIN MIRONIZD loriosa superba L. - Seed 94.0% 101.0% by HPL Antigout Anti-wrinkles, ollagen synthesis enhancer OLHIOSID loriosa superba L. - Seed 85.0% by HPL hemical intermediate 10-DATYLBAATIN III Taxus baccata L. - Twig and leaf 96.0% by HPL hemical intermediate DOTAXL Taxus baccata L. - Twig and leaf 97.0% 102.0% by HPL Antimitotic / Anticancer SULOSID Aesculus hippocastanum L. - Bark of branch 98.0% by HPL Vasokinetic, apillary protectant 18β-LYYRRHTINI AID UR. PH. lycyrrhiza glabra L.- Root, rhizome 98.0% 101.0% by acidimetry Anti-inflammatory 18β-LYYRRHTINI AID lycyrrhiza glabra L.- Root, rhizome 98.0% 102.0% by acidimetry Soothing, Lenitive ALANTHAMIN BROMIDRAT Narcissus pseudonarcissus L. - Bulb 98.0% 102.0% by HPL Antialzheimer PALITAXL Taxus media Rehder - Root, leaf and twig 97.0% 102.0% by HPL Antimitotic / Anticancer PALITAXL S Taxus baccata (L.) - leaf and twig 97% 102% by HPL Antimitotic / Anticancer PHARMAUTIAL HALTH - FOOD PRSONAL AR compliance with cmps and in pharmaceutical inspected suites, supported by TD-DMFs. under Hazard Analysis and rytical ontrol Points (HAP) Indena s Personal are ingredients are RAH registered RAS: ORT KOSHR P 6 7 PAKAIN MATRIALS :: Food

5 ISOLATD or SMISYNTHTI PUR PRODUTS PUR MOLULS ISOLATD OR DRIVD FROM PLANTS (continue) BRAND - NLISH NAM BOTANIAL ORIIN ASSAY BIOLOIAL ATIVITY PRAJMALIN Rauvolfia vomitoria Afz. - Root bark 98% 102% by potentiometry Antiarrhythmic RSRPIN Rauvolfia vomitoria Afz. - Root bark 99.0% 101.0% by potentiometry Antihypertensive RSRPIN USP Rauvolfia vomitoria Afz. - Root bark 97.0% 101.0% by HPL Antihypertensive RSRPIN MIRONIZD Rauvolfia vomitoria Afz. - Root bark 99.0% 101.0% by potentiometry Antihypertensive SRIOSID Terminalia sericea Burch. ex D.- Root bark 76.0% 84.0% by HPL Antiwrinkles, Soothing, Redensifier THIOOLHIOSID loriosa superba L. - Seed 98.0% 102.0% by potentiometry Muscle relaxant THIOOLHIOSID B loriosa superba L. - Seed 98.0% 102.0% by potentiometry Muscle relaxant VISNADIN Ammi visnaga (L.) Lam - Umbel without fruits 90.0% by HPL Vasokinetic PHARMAUTIAL HALTH - FOOD PRSONAL AR compliance with cmps and in pharmaceutical inspected suites, supported by TD-DMFs. under Hazard Analysis and rytical ontrol Points (HAP) Indena s Personal are ingredients are RAH registered RAS: ORT KOSHR P 8 9 PAKAIN MATRIALS :: Food

6 STANDARDIZD, PURIFID or OTHR HARATRIZD DRY XTRATS DRY XTRATS WITH RPRODUIBL ONTNT OF HARATRISTI PRINIPLS BRAND - NLISH NAM BOTANIAL ORIIN ASSAY BIOLOIAL ATIVITY ALDR BUKTHORN K Frangula alnus Miller (Rhamnus frangula L.) - Bark 15.0% hydroxyanthracene heterosides calculated as glucofrangulin A Laxative ASULUS HIPPOASTANUM DRY XTRAT Aesculus hippocastanum L. - Seed 63.0% 77.0% of saponins, expressed as escine by spectrophotometry, 50.0% of beta-escine by HPL Antioxidant activity, apillarotropic INARAN - ARTIHOK H ynara cardunculus L. - Flowering head, leaves % of caffeoylquinic acids by spectrophotometry holesterol and Intestinal health BILAR HK ynara cardunculus L. - Leaf 0.3% flavonoids expressed as luteolin-7-o-glucoside, 2.5% caffeoylquinic acid expressed as chlorogenic acid, 0.6% chlorogenic acid by HPL holesterol and Intestinal health ARTIHOK H ynara cardunculus L. - Flowering head, leaves 50.0% of caffeoylquinic acids by HPL holesterol and Intestinal health BANBLOK - BAN Phaseolus vulgaris L. - ommon bean MIRTOSLT - BILBRRY HK Vaccinium myrtillus L. - Fresh frozen fruit 6.0% as alpha amylase inhibitor by HPL; 1,100 U/mg of alpha amylase inhibiting activity; 30,000 HAU/g of hemagglutinating activity by spectroph./enzym. 36.0% of anthocyanins by HPL; 25.0% of anthocyanins as anthocyanidins by spectrophotometry Appetite regulator, Healthy blood sugar metabolism ye health, apillarotropic, Antioxidant activity MYRTOYAN - BILBRRY Vaccinium myrtillus L. - Fresh frozen fruit 32.4% 39.6% of anthocyanins by HPL, 1% anthocyanidins by HPL ye health, apillarotropic BLAK OHOSH K imicifuga racemosa (L.) Nutt. - Rhizome and root 5% of total triterpenic glycosides Menopause-related symptoms controller BLADDRWRAK K Fucus vesiculosus L. - Thallus 0.2% of fucosterol by TL; 0.2% of iodine according to DAB method Weight control agent, Anticellulite BOLDO K Peumus boldus L. - Leaf and bark 0.05% of boldin by TL; 0.2% of total alkaloids by acidometry holeretic agent BUTHR S BROOM K Ruscus aculeatus L. - Rhizome and root 9.0% 11.0% of saponins calculated as ruscogenins by spectrophotometry AP ALOS K Aloe ferox L. - Leaf 19.0% 21.0% of hydroxyanthracene derivatives expressed as barbaloin Laxative PURSLT - ASANTHRANOL Rhamnus purshiana D.- Bark 24.0% 26.5% of cascarosides expressed as cascaroside A by spectrophotometry Vasoprotectant Laxative PHARMAUTIAL HALTH - FOOD PRSONAL AR compliance with cmps and in pharmaceutical inspected suites, supported by TD-DMFs. under Hazard Analysis and rytical ontrol Points (HAP) Indena s Personal are ingredients are RAH registered RAS: ORT KOSHR P PAKAIN MATRIALS :: Food

7 STANDARDIZD, PURIFID or OTHR HARATRIZD DRY XTRATS DRY XTRATS WITH RPRODUIBL ONTNT OF HARATRISTI PRINIPLS (continue) BRAND - NLISH NAM BOTANIAL ORIIN ASSAY BIOLOIAL ATIVITY ASARA SARADA K Rhamnus purshiana D. - Bark NTVITA H entella asiatica (L.) Urban - Leaf NTLLA ASIATIA SLTD TRITRPNS entella asiatica (L.) Urban - Leaf 20.0% 25.0% of cascarosides expressed as cascaroside A by spectrophotometry 45.0% of the sum of asiaticoside, madecassoside, asiatic and madecassic acids by HPL 36.0% 44.0% of asiaticoside, 56.0% 64.0% of genins as sum of asiatic acid and madecassic acid by HPL Laxative ollagen restructurant, Antiwrinkles agent Antiwrinkles, Stretchmarks improver HAMOMIL K Matricaria recutita L. - Flowering head, leaves 1.2% of total apigenin by HPL Spasmolytic, Soothing, Lenitive OLUS oleus barbatus Benth. - Rhizome and root 80.0% of forskolin by HPL Lipolytic, Vasokinetic, camp stimulant DVIL S LAW H Harpagophytum procumbens D. - Root 1.8% 2.2% of harpagoside by HPL Joint health IMMUNOSLT HINAA ANUSTIFOLIA K chinacea angustifolia D. - Root 4.0% of echinacoside by HPL Immunomodulator, Antioxidant activity, Soothing POLINAA HINAA ANUSTIFOLIA chinacea angustifolia D. - Root 2.0% of echinacoside by HPL, 5.0% of IDN 5405, 0.1% of isobutylamides Immunomodulator HINAA PURPURA K chinacea purpurea (L.) Moench - Root 0.8% of caftaric, chicoric, chlorogenic acids and echinacoside by HPL Immunomodulator LUTHROOUS H leutherococcus senticosus (Rupr. & Maxim) Maxim - Root 0.5% of eleutheroside by HPL Tonic, Immunomodulator SIN Aesculus hippocastanum L. - Seed 97.0% 103% by potentiometry Antioedema, apillarotropic SIN FR AID Aesculus hippocastanum L. - Seed 95.0% by potentiometry Antioedema SIN WATR SOLUBL Aesculus hippocastanum L. - Seed 97.0% 103.0% by potentiometry Antioedema INKOSLT INKO BILOBA H inkgo biloba L. - Leaf 24.0% of ginkgoflavonglucosides, 6.0% as a sum of ginkgolides A, B, and bilobalide, 2.6% 3.2% of bilobalide, 5.0 ppm of total ginkgolic acids by HPL Blood circulation improver PHARMAUTIAL HALTH - FOOD PRSONAL AR compliance with cmps and in pharmaceutical inspected suites, supported by TD-DMFs. under Hazard Analysis and rytical ontrol Points (HAP) Indena s Personal are ingredients are RAH registered RAS: ORT KOSHR P PAKAIN MATRIALS :: Food

8 STANDARDIZD, PURIFID or OTHR HARATRIZD DRY XTRATS DRY XTRATS WITH RPRODUIBL ONTNT OF HARATRISTI PRINIPLS (continue) BRAND - NLISH NAM BOTANIAL ORIIN ASSAY BIOLOIAL ATIVITY INKO BILOBA UR. PH. inkgo biloba L. - Leaf INKO BILOBA DIMRI FLAVONOIDS INKO BILOBA HF H inkgo biloba L. - Leaf INKO BILOBA HF TRPNS FR H 22.0% 27.0% of flavonoids, 2.6% 3.2% of bilobalide, 2.8% 3.4% of ginkgolides A,B,, 5.0 ppm of ginkgolic acids by HPL Blood circulation improver inkgo biloba L. - Leaf 24.0% 39.0% of total biflavones expressed as ginkgetin by HPL Antioxidant activity, Lipolytic inkgo biloba L. - Leaf 24.0% of ginkgoflavoglucosides, 6.0% as sum of ginkgolides A, B, and bilobalide, 5.0 ppm of total ginkgolic acids by HPL 24.0% of ginkgoflavonglucosides, 0.1% of sum of ginkgolides A, B, and bilobalide by HPL INSN 18-22% Panax ginseng.a. Meyer - Root 18.0% 22.0% of total ginsenosides and malonylginsenosides by HPL Adaptogen, Tonic INSN 27-30% H Panax ginseng.a. Meyer - Root INSLT - INSN IDB H Panax ginseng.a. Meyer - Root RD LAF RAP H Vitis vinifera L. - Leaf LUOSLT RAP SD XTRAT NOVITA RAP SD XTRAT HK HK Vitis vinifera L. - Seed Vitis vinifera L. - Seed RAP SD MONOMRS H Vitis vinifera L. - Seed RNSLT - RN TA K amellia sinensis (L.) O. Kuntze - Young leaf RN TA H amellia sinensis (L.) O. Kuntze - Young leaf 27.0% 30.0% of saponins by spectrophotometry; 20.0% of total ginsenosides by HPL 7.0% of ginsenosides and malonylginsenosides, 0.9% 1.4% of Rg1, 1.7% 3.0% of Rb1 by HPL 3.0% of total flavonoids (isoquercitrin, quercetin-3-o-b-d-glucuronide and kaempferol-3-o-glucoside) by HPL; 0.3% of anthocyanins by spectrophotometry 95.0% 105.0% of proanthocyanidins by P; 13.0% 19.0% of catechin and epicatechin by HPL 95.0% of proanthocyanidins by spectrophotometry, 5.0% 15.0% of catechin and epicatechin by HPL 95.0% 105.0% of proanthocyanidins by L; 20.0% 30.0% of catechin and epicatechin by HPL 60.0% of total polyphenols, 40.0% of (-)-epigallocatechin-3-o-gallate, 0.1% of caffeine by HPL 40.0% of total polyphenols by spectrophotometry, 15.0% of total catechin expressed as epigallocatechin-3-o-gallate, 6% of epigallocatechin-3-o-gallate; 5.0% of caffeine by HPL ognition and circulation improver, Antioxidant activity, Vasokinetic ognition and circulation improver, Antioxidant activity, Vasokinetic Adaptogen, Tonic Adaptogen, Tonic, lasticizing Antioxidant activity, apillaro- and venotropic agent Antioxidant activity, apillarotropic Antioxidant activity, apillarotropic Antioxidant activity, apillarotropic Antioxidant activity, Antidecay, Whitener Tonic, Antioxidant activity PHARMAUTIAL HALTH - FOOD PRSONAL AR compliance with cmps and in pharmaceutical inspected suites, supported by TD-DMFs. under Hazard Analysis and rytical ontrol Points (HAP) Indena s Personal are ingredients are RAH registered RAS: ORT KOSHR P PAKAIN MATRIALS :: Food

9 STANDARDIZD, PURIFID or OTHR HARATRIZD DRY XTRATS DRY XTRATS WITH RPRODUIBL ONTNT OF HARATRISTI PRINIPLS (continue) BRAND - NLISH NAM BOTANIAL ORIIN ASSAY BIOLOIAL ATIVITY UARANA K Paullinia cupana H.B. et K. - Seed 11.0% 13.0% of total alkaloids by HPL Tonic, Stimulant, Mild diuretic, Lipolytic HAWTHORN K rataegus spp. - Flowering top 1.8% of vitexin-2 -O-rhamnoside by spectrophotometry ardiovascular health, Antioxidant activity HD-MUSTARD H Sisymbrium officinale (L.) Scop. - Herb 0.5% of glucosinolates by HPL xpectorant HOPS H Humulus lupulus L. - Flowered head 0.3% of flavonoids by HPL Stress reliever HORS HSTNUT K Aesculus hippocastanum L. - Seed HORS HSTNUT BARK DRY XTRAT HORSTAIL H quisetum arvense L. - Herb 16.0% 22.0% of saponins expressed as escin by spectrophotometry Antioedema, Venotropic Aesculus hippocastanum L. - Bark 20.0% of esculoside, esculetin, fraxetin and fraxin by HPL apillarotropic 2.6% 3.2% of silica and 0.8% of total flavonoids expressed as isoquercetin by spectrophotometry Hair / Nail fragility reducer IVY DRY HYDROALOHOLI XT. Hedera helix L. - Leaf 5.0% of hederacoside by HPL Venotropic, xpectorant KOLA K ola nitida (Vent.) Schott et ndl. - Seed 9.5% 13.0% of alkaloids by gravimetry Lipolytic LMON BALM K Melissa officinalis L. - Flowered head 10.0% of hydroxycinnamic derivates calculated as rosmarinic acid Anxiolytic LINDN TR H Tilia cordata Mill. /Tilia platyphyllos Scop. - Flower 0.5% of flavonoids by HPL Spasmolytic, Antioedema LYMPHASLT - MLILOTUS H Melilotus officinalis (L.) Pallas - Herb 17.0% 20.0% of coumarin by HPL Lymphatic circulation improver MILLT H Panicum miliaceum L. - Seed 3.0% of fatty acids by Skin restructurant, Skin barrier function improver MILLT H Panicum miliaceum L. - Seed 7.0% 10.0% of fatty acids by ; 40.0% 60.0% of methionine by HPL Skin restructurant PHARMAUTIAL HALTH - FOOD PRSONAL AR compliance with cmps and in pharmaceutical inspected suites, supported by TD-DMFs. under Hazard Analysis and rytical ontrol Points (HAP) Indena s Personal are ingredients are RAH registered RAS: ORT KOSHR P PAKAIN MATRIALS :: Food

10 STANDARDIZD, PURIFID or OTHR HARATRIZD DRY XTRATS DRY XTRATS WITH RPRODUIBL ONTNT OF HARATRISTI PRINIPLS (continue) BRAND - NLISH NAM BOTANIAL ORIIN ASSAY BIOLOIAL ATIVITY OLASLT - OLIV HK Olea europaea L. - Fruit OPXTAN - OLIV HK Olea europaea L. - Fruit 30.0% of total polyphenols by spectrophotometry; 1.5% of hydroxytyrosol, 5.0% of verbascoside by HPL 10.0% of total polyphenols by spectrophotometry; 2.0% 3.5% of verbascoside, 4.5% of hydroxytyrosol and its derivatives by HPL Antioxidant activity, Healthy cardiovascular function Antioxidant activity, UV protectant, Healthy cardiovascular function PASSION FLOWR K Passiflora incarnata L. - Aerial part 4.0% of flavonoids as vitexin by spectrophotometry Spasmolytic, Mild sedative PASSION FLOWR H Passiflora incarnata L. - Aerial part 2.0% 2.6% of total flavonoids by spectrophotometry Spasmolytic, Mild sedative RATHANY Krameria lappacea (Dombey) Burdet - Root 13.5% 16.5% of neolignans, expressed as eupomatenoide-6 by HPL Antioxidant activity, Antimicrobic RHUBARB K Rheum emodi Wall. - Rhizome 9.0% 11.0% of total anthraquinones calculated as aloe-emodin upeptic, Laxative RUSONINS RUSONINS SNNOSIDS 45% Ruscus aculeatus L. - Rhizome and root Ruscus aculeatus L. - Rhizome and root assia angustifolia Vahl. - Leaf 95.0% 103.0% of ruscogenins, 65.0% 80.0% neoruscogenin, 20.0% 35.0% ruscogenin by HPL 92.0% 103.0% of ruscogenins, 60.0% 80.0% of neoruscogenin, 20.0% 40.0% of ruscogenin by HPL 42.5% 47.5% of hydroxyanthracene glycosides, calculated as sennoside B by spectrophotometry SNNOSIDS 60% assia angustifolia Vahl. - Leaf 55.0% 65.0% of sennosides by spectrophotometry Laxative SILYMARIN K Silybum marianum (L.) aertn. - Fruit MADLUYL UNIA JAMBOLANA SOYSLT - SOYBAN 50.0% 60.0% of silymarin calculated as silybin by HPL according to Ph. ur. (corresponding to NTL 65% according to DAB % by spectrophotometry) Antihaemorrhoidal, Venotropic Anticellulite, Vasoprotectant Laxative Healthy liver, Antioxidant activity K Syzygium cumini (L.) Skeels - Seed 2.0% of ellagic acid by HPL; hypoglycemic effect 20.0% Healthy blood sugar metabolism lycine max (L.) Merr. - Seed 18.0% of B-type saponins, 13.0% 17.0% of isoflavone glycosides by HPL Menopause-related symptoms controller ST. JOHN S WORT Hypericum perforatum L. - Flowering top 0.10% 0.30% of total hypericin, 6.0% of flavonoids, 6.0% of hyperforin by HPL Antidepressant PHARMAUTIAL HALTH - FOOD PRSONAL AR compliance with cmps and in pharmaceutical inspected suites, supported by TD-DMFs. under Hazard Analysis and rytical ontrol Points (HAP) Indena s Personal are ingredients are RAH registered RAS: ORT KOSHR P PAKAIN MATRIALS :: Food

11 STANDARDIZD, PURIFID or OTHR HARATRIZD DRY XTRATS DRY XTRATS WITH RPRODUIBL ONTNT OF HARATRISTI PRINIPLS (continue) BRAND - NLISH NAM BOTANIAL ORIIN ASSAY BIOLOIAL ATIVITY ST. JOHNSLT ST. JOHN S WORT Hypericum perforatum L. - Flowering top 0.3% of hypericin like substances by spectrophotometry, 3.0% of hyperforin by HPL Healty mood ST. JOHN S WORT H Hypericum perforatum L. - Flowering top 0.27% 0.33% of total hypericin by spectrophotometry Healty mood TURMRI DRY XTRAT K urcuma longa L. - Rhizome 4.0% of curcumin like derivatives as curcumin by spectrophotometry Healthy inflammatory response XILOL - TAMARIND SD POLYSAHARID Tamarindus indica L. - Seed 85.0% of xyloglucane by HPL Moisturizer, Skin restructurant, Antiwrinkles XIMNOIL - XIMNYNI AID Santalum album L. - Seed 98.0% 105% by potentiometry Vasokinetic, Skin nourishing VALROSLT - VALRIAN K Valeriana officinalis L. - Rhizome and root 0.8% of valerenic acids by HPL Sedative WILLOW BARK H Salix spp. - Twig and bark 15.0% of salicin by HPL Healty inflammatory response, Joint health PHARMAUTIAL HALTH - FOOD PRSONAL AR compliance with cmps and in pharmaceutical inspected suites, supported by TD-DMFs. under Hazard Analysis and rytical ontrol Points (HAP) Indena s Personal are ingredients are RAH registered RAS: ORT KOSHR P PAKAIN MATRIALS :: Food

12 HARATRIZD, STANDARDIZD OILY and SOFT XTRATS OILY / SOFT XTRATS WITH RPRODUIBL ONTNT OF HARATRISTI PRINIPLS BRAND - NLISH NAM BOTANIAL ORIIN ASSAY BIOLOIAL ATIVITY URBILN - PUMPKIN SDS K ucurbita pepo L. - Naked seed 85.0% of fatty acids by OMABLU - BILBRRY SD Vaccinium myrtillus L. - Seeds 80.0% total fatty acids by ; 50% total polyunsaturated fatty acids by L PRUNUSLT PYUM AFRIANUM HINS RHUBARB SOFT AQUOUS XTRAT SABALSLT SAW PALMTTO SAW PALMTTO SAW PALMTTO ALOHOLI XTRAT Healthy prostate and bladder function, Skin matting agent holesterol health, Skin restructurant, Lenitive. H Prunus africana (Hook. F.) Kalkm. - Bark 11.7% 14.3% of total sterols by spectrophotometry Healthy prostate and bladder function K K Rheum palmatum L. - Rhizome 1.0% of anthraquinones as aloe-emodin by spectrophotometry Laxative Serenoa repens (Bartr.) Small - Fruit Serenoa repens (Bartr.) Small - Fruit Serenoa repens (Bartr.) Small - Fruit 85.0% 95.0% of fatty acids, 0.01% 0.15% of fatty alcohols, 0.25% 0.50% of total sterols, 0.15% 0.35% of β-sitosterol by 85.0% 95.0% of fatty acids, 0.15% 0.30% of fatty alcohols, 0.20% 0.40% of total sterols, 0.10% 0.30% of β-sitosterol by 85.0% 95.0% of fatty acids, 0.01% 0.15% of fatty alcohols, 0.25% 0.50% of total sterols, 0.15% 0.35% of β-sitosterol by XIMILN - THYLXIMNYNAT Santalum album L. - Seed 70.0% of ethylximenynate by HPL Vasokinetic ZANTHALN - ZANTHOXYLUM Zanthoxylum bungeanum Maxim. - Pericarp 4.4% 6.4% of alkylamides by HPL Healthy prostate and bladder function, Anti 5-α reductase Antiandrogen, Anti-BPH Healthy prostate and bladder function Antiitching, Skin sensitivity modulator, Lifting agent PHARMAUTIAL HALTH - FOOD PRSONAL AR compliance with cmps and in pharmaceutical inspected suites, supported by TD-DMFs. under Hazard Analysis and rytical ontrol Points (HAP) Indena s Personal are ingredients are RAH registered RAS: ORT KOSHR P PAKAIN MATRIALS :: Food

13 PHYTOSOM MOR BIOAVAILABL ATIV INRDINTS BRAND - NLISH NAM BOTANIAL ORIIN ASSAY BIOLOIAL ATIVITY BOSXIL FRANKINNS PHYTOSOM Boswellia serrata Roxb. ex olebr. - Resin 25.0% of boswellic acids by HPL Soothing, Lenitive, Anti-photoageing ASPROM BOSWLLIA PHYTOSOM Boswellia serrata Roxb. ex olebr. - Resin 25.0% of boswellic acids by HPL Healthy inflammatory response NTLLA ASIATIA SLTD TRITRPNS H entella asiatica (L.) Urban - Leaf 30.0% 35.0% of selected triterpenes by HPL ollagen restructurant, Antiwrinkles agent PHYTOSOM SIN β-sitostrol PHYTOSOM Aesculus hippocastanum L. - Seed 32.0% 40.0% of escin by TL, 12.5% 15.5% of β-sitosterol by TL apillarotropic INKOSLT PHYTOSOM INKO BILOBA PHYTOSOM K inkgo biloba L. - Leaf VIRTIVA - INKO BILOBA PHOSPHATIDYLSRIN H inkgo biloba L. - Leaf PHYTOSOM 7.0% of ginkgoflavonglucosides, 2.0% of ginkgoterpenes, 0.8% of bilobalide, 0.8% of ginkgolides, 5 ppm of total ginkgolic acids by HPL 5.0% of ginkgoflavonglucosides, 0.5% of ginkgoterpenes, 12.0% of phosphatidylserine by HPL INKO BILOBA DIMRI FLAVONOIDS inkgo biloba L. - Leaf 10.0% of total biflavones expressed as ginkgetin by HPL PHYTOSOM INKO BILOBA TRPNS PHYTOSOM inkgo biloba L. - Leaf 30.0% of total ginkgoterpenes, 10.0% of bilobalide, 10.0% of ginkgolides A, B,, J by HPL ognition and circulation improver, Antioxidant activity, Vasokinetic ognitive enhancer Lipolytic, Vasokinetic, Phosphodiesterase inhibitor Soothing, Lenitive, Antiallergic agent INSLT PHYTOSOM INSN IDB PHYTOSOM K Panax ginseng.a. Meyer - Root 30.0% 40.0% of ginseng typical constituents by gravimetry Adaptogen, Tonic, Skin elasticity improver PHARMAUTIAL HALTH - FOOD PRSONAL AR compliance with cmps and in pharmaceutical inspected suites, supported by TD-DMFs. under Hazard Analysis and rytical ontrol Points (HAP) Indena s Personal are ingredients are RAH registered RAS: ORT KOSHR P PAKAIN MATRIALS :: Food

14 PHYTOSOM MOR BIOAVAILABL ATIV INRDINTS (continue) BRAND - NLISH NAM BOTANIAL ORIIN ASSAY BIOLOIAL ATIVITY 18β-LYYRRHTINI AID PHYTOSOM lycyrrhiza glabra L.- Root 27.0% 31.0% of 18β-glycyrrhetinic acid by HPL Soothing, Lenitive RNSLT PHYTOSOM RN TA PHYTOSOM HK amellia sinensis (L.) O. Kuntze - Young leaf HAWTHORN PHYTOSOM rataegus spp. - Flowering top 19.0% 25.0% of polyphenols expressed as (-)-epigallocatechin-3-ogallate, 13.0% of (-)-epigallocatechin-3-o-gallate, 0.1% of caffeine by HPL 3.0% of vitexin-2 -O-rhamnoside by HPL 28.0% 34.0% of Hawthorn typical constituents LUOSLT PHYTOSOM RAP SD PHYTOSOM Vitis vinifera L. - Seed 25.0% 30.0% of proanthocyanidins by P PROANTHOYANIDIN A2 PHYTOSOM Aesculus hippocastanum L. - Bark 31.0% 37.0% of proanthocyanidin A2 by HPL RXATROL RSVRATROL PHYTOSOM Polygonum cuspidatum Sieb. e Zucc. - Rhizome 30.0% of resveratrol by HPL SRIOSID PHYTOSOM Terminalia sericea Burch. ex. D. - Root bark 25.0% of sericoside by HPL SILYMARIN PHYTOSOM K Silybum marianum (L.) aertn. - Fruit 15.0% 20.0% of flavolignans calculated as silybin by HPL SILIPHOS SILYBIN PHYTOSOM HK Silybum marianum (L.) aertn. - Fruit 29.7% 36.3% of silybin by HPL Healthy liver MRIVA TURMRI PHYTOSOM HK urcuma longa L. - Rhizome 18.0% 22.0% of curcuminoids by HPL VISNADX VISNADIN PHYTOSOM Ammi visnaga (L.) Lam. - Umbel without fruits 10.0% 13.0% of visnadin by TL Vasokinetic Antioxidant activity, Weight loss agent ardiovascular health, Antioxidant activity Healthy cardiovascular function, UV protectant, Antioxidant activity UV protectant, Firming and oval reshaping agent Antioxidant activity, Antiageing, Sirt 1 modulator Antioxidant activity, UV protectant, Antiwrinkles, Soothing, Redensifier Healthy liver, Antioxidant activity, UV protectant Joint health, Healthy inflammatory response, Soothing PHARMAUTIAL HALTH - FOOD PRSONAL AR compliance with cmps and in pharmaceutical inspected suites, supported by TD-DMFs. under Hazard Analysis and rytical ontrol Points (HAP) Indena s Personal are ingredients are RAH registered RAS: ORT KOSHR P PAKAIN MATRIALS :: Food

15 FOOD & FLAVOURS BOTANIAL XTRATS WITH ORANOLPTI PROPRTIS BRAND - NLISH NAM BOTANIAL ORIIN ASSAY BIOLOIAL ATIVITY TOLU BALSAM XTRAT K Myroxylon balsamum (L.) Harms var. balsamum 32.0% 38.0% of sucrose by oxidimetry Flavouring, Sweet QUASSLT - QUASSIA HK Picrasma excelsa (Sw.) Planch. / Quassia amara L. - Wood 53.0% 57.0% as sum of quassin and neoquassin Flavouring, Bitter VANILLA K Vanilla planifolia (B. D. Jackson) - apsule 5.0% of vanillin Flavouring, Sweet INHONA K inchona spp. - Bark 19.0% 21.0% of total alkaloids Flavouring, Bitter AMMONIUM LYYRRHIZAT K lycyrrhiza glabra L.- Root 98.0% 102.0% of monoammonium glycyrrhizate Flavouring, Sweet LYAMIL OMPOUND N K lycyrrhiza glabra L.- Root 9.5% 10.5% of triterpenic glucosides as monoammonium glycyrrhizate Flavouring, Sweet LIORI K lycyrrhiza glabra L.- Root 5.0% 6.2% of glycyrrhizic acid Flavouring, Sweet FOOD & FLAVOURS RAS: ORT KOSHR P PAKAIN MATRIALS :: Food

16 HADQUARTRS - INDNA S.p.A. Viale Ortles, Milan - Italy tel INDNA BIOTHNOLOY (Shanghai) o., Ltd. Unit 03, 16/F, ross Tower, 318 Fu Zhou Road Shanghai hina tel DPR /2011* 05/2015 INDNA Brasil Ltda Rua Bandeira Paulista, 600 P São Paulo - Brazil tel INDNA JAPAN o., Ltd. KDDI Bld. 21F Otemachi hyoda-ku Tokyo Japan tel INDNA USA Inc. Two Union Square 601 Union Street, Suite 330 Seattle, WA USA tel INDNA S.A.S. 23, Rue de Madrid Paris - France tel indena.com

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