Exercise and Hypermobility

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1 Exercise and Hypermobility Dr Roger Wolman MD FRCP FFSEM Consultant in Rheumatology Consultant in Sport and Exercise Medicine Royal National Orthopaedic Hospital

2 Exercise and Hypermobility Why exercise? Understanding exercise Exercise physiology Considerations for patients with EDS/hypermobility

3 Why Exercise? Numerous health benefits If the effects of exercise could be wrapped up in tablet and patented by a Pharmaceutical Company then it would be widely prescribed BUT No financial gain Poor compliance

4 Why Exercise? Prevention and management of Diabetes Obesity Cardiovascular disease Hypertension Osteoporosis Depression/anxiety Arthritis

5 Types of exercise training Aerobic Strength Flexibility Balance/coordination/proprioception

6 Aerobic (cardiorespiratory) exercise Transfer of oxygen to muscle Stimulates Heart Lung Red cells Muscle

7 Aerobic (cardiorespiratory) exercise Increased energy expenditure Metabolic changes Increased insulin sensitivity Improved lipid profile

8 Exercise prescription Aerobic exercise Moderate intensity - Sing-talk test 150 min per week (children 300 min/week) 30 min x 5 per week (10 min episodes) eg Walking High intensity 75 min/week eg Running

9 Strength training Enhances strength Muscle Ligament Tendon Bone Reduced risk of injury Metabolic changes Insulin sensitivity Increased RMR

10 Exercise prescription Strength training 8 10 strength training exercises 8 12 repetitions of each exercise Twice a week

11 Flexibility training Reduced risk of injury Improvement in posture

12 Balance/coordination/proprioceptive training Reduced risk of injury Reduced risk of falls Tai Chi

13 Exercise prescription Balance/proprioceptive training Single leg standing Eyes open Eyes closed Balance board exercises Tai Chi

14 Exercise and Type 2 Diabetes Prevention Jeon CY et al. Physical activity of Moderate Intensity and risk of Type2 Diabetes. A systematic review. Diabetes Care 2007; 30: prospective cohort studies of 301,221 subjects RR of Type 2 Diabetes 0.69 for regular physical activity moderate intensity 0.70 for regular walking (>2.5 hours per week) This effect is independent of BMI Effect still applies in those who do not lose weight

15 Exercise and Hypertension Multiple clinical trials have shown. that regular exercise can lead to a reduction in systolic BP of 10mmHg and in diastolic of 8mmHg Kokkinos et al. Exercise as hypertension therapy. Cardiol Clin 2002; 19: Moderate exercise in the form of walking seems to be adequate Sohn et al. Impact of exercise (walking) on blood pressure levels in African Amercian adults with newly diagnosed hypertension. Eth Dis 2007;17:1049 Hua et al. Effects of low intensity exercise conditioning on BP, heart rate & autonomic modulation of heart in hypertension. Biol Res Nurs 2009; 11:129

16 Exercise and Hypertension Westhoff et al. Too old to benefit from sport? The cardiovascular effect of exercise training in Elderly with systolic hypertension. Kid Blood Pre Res 2007; 30: Subjects>60yrs Exercise programme Treadmill walking 30 mins x 3 per week Moderate intensity

17 Exercise and lipidaemia Regular aerobic exercise will Raise HDL cholesterol Lower LDL cholesterol Halverstadt et al. Endurance exercise training raises HDL cholesterol and lowers LDL independent of body fat phenotypes in older men and women. Metabolism: Clin & Exp 2007; 56: yr olds; moderate aerobic exercise over 24 weeks Kodama et al. Effect of aerobic exercise training on serum levels of HDL cholesterol. Arch Int Med. 2007; 167;999 Meta-analysis 120 minutes of aerobic exercise per week

18 Exercise and Cardiovascular disease Thompson PD et al. AHA Scientific Statement. Exercise & Physical Activity in the prevention and treatment of Atherosclerotic Cardiovascular Disease. Circulation 2003; 107: Exercise and Physical Activity Prevention of atherosclerotic CAD Treatment of CAD, HF and Claudication Reducing risk factors Lipids Hypertension Glucose intolerance

19 Exercise and Obesity Needs to be combined with a reducing diet Fit & obese is much better than Unfit & obese Fit & obese is better than Unfit and normal weight eg diabetic risk

20 Exercise and Stress/Anxiety/Depression Evidence that aerobic exercise is effective in the management of Mild depression May be more effective than medication Major depressive disorder Anxiety disorders Stress Barbour et al. Exercise as a treatment for Depression and other Psychiatric disorders. J Cardiopul Rehab Prev. 2007; 27;359. Cochrane review 2010 states that it is effective but not yet enough evidence to give recommendations of the relative merits of aerobic or resistance training and of individual or group sessions

21 Exercise and Depression Slowly progressive exercise will improve selfworth and self-efficacy The social interaction of a group exercise class may be helpful

22 Exercise and Arthritis Osteoarthritis of the knee Strength and aerobic training Cochrane review 2009 Osteoarthritis of the hip Less clear evidence for the use of exercise therapy Cochrane review 2009

23 Exercise and Chronic low back pain Aerobic exercise Stability exercise Cochrane reviews 2010 recurrent low back pain - non-specific low back pain

24 Exercise and Fibromyalgia/chronic widespread pain and chronic fatigue Chambers et al. Interventions for the treatment, management and rehabilitation of patients with CFS: an updated systemic review. J R Soc Med 2006; 99: Cochrane review 2008 Supervised aerobic exercise programme has a beneficial effect on physical capacity and fibromyalgia symptoms Strength training may also have a beneficial effect

25 Exercise and Osteoporosis/Falls Aerobic, weight-bearing and resistance exercise are all effective in increasing Spinal BMD Walking effective in the hip Exercise focusing on strength, balance and endurance can all reduce the risk of falls eg Tai Chi Cochrane reviews 2009

26 Exercise prescription for patients with EDS/Hypermobility EDS classic (types I & II), Vascular (type IV) Need to be cautious about exercise Avoid contact sport Avoid high intensity activity Focus on low impact aerobic activity, eg swimming, exercise bike Low/moderate load strength training Balance and proprioceptive training Eg Pilates, Tai Chi, Yoga

27 Exercise prescription for EDS hypermobility type Neuromuscular considerations Joint laxity subluxation dislocation Impaired proprioception/balance awareness Musculoskeletal pain Deconditioning Reduced aerobic fitness Reduced muscle strength FATIGUE

28 Exercise prescription for EDS hypermobility type The deconditioning is reversible through exercise Reduced fatigue Improved function Improved pain tolerance Reduce symptoms of POTS So what would an exercise programme look like in a patient with EDS-hypermobility type?

29 Exercise prescription for EDS hypermobility type Avoid contact sport Avoid high impact but..

30 Exercise prescription for EDS hypermobility type Address deconditioning with graded exercise programme Aerobic exercise Walking Alternatives: Cycling, swimming Wheelchair exercises including cycling Strength training Pilates Using own body weight

31 Exercise prescription for EDS hypermobility type Address impaired balance/proprioception through Closed chain exercises Eyes open/eyes closed standing Pilates Tai Chi

32 Exercise prescription for EDS hypermobility type Principles of safe exercise Slow, progressive increase in activity Initially short duration and frequency eg twice/week Gradually increase duration and frequency Aim: mins exercise most days/week Monitor by level of carryover pain after activity Duration and intensity Accept a degree of post exercise stiffness that can last for 48 hrs

33 Summary Regular exercise is a key factor in the management of patients with the Hypermobility syndrome Treatment of many aspects of the syndrome Enhancing health and wellbeing Consider 3 types of exercise training Aerobic Strength Proprioceptive

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