The Oslo Tomosynthesis Screening Trial
|
|
|
- Harry Eaton
- 9 years ago
- Views:
Transcription
1 British Society of Breast Radiology BSBR Liverpool November 11, 2013 The Oslo Tomosynthesis Screening Trial Professor dr. med. Per Skaane Oslo University Hospital Ullevaal Breast Imaging Center Oslo / Norway [email protected] 30 min
2 British Society of Breast Radiology BSBR Liverpool November 11, 2013 Objectives: Tomosynthsis (DBT) in breast cancer screening Potential role of tomosynthesis in screening Do we need 2D? Tomo in both (CC + MLO) views? The potential role of synthetic 2D images Background for study design of the Oslo trial Preliminary results from the Oslo Tomosynthesis Screening Trial (OTST) Summary of DBT in screening and conclusions Disclosure: Oslo Tomosynthesis Screening Trial Equipment and support for additional reading provided by Hologic, Inc.
3 Tomosynthesis ( 3D Mammography ) Screening unit Oslo ( Galleriet ) Oslo Tomosynthesis Screening Trial : Two Dimensions ( Hologic)
4 BREAST TOMOSYNTHESIS ACQUISITION X-ray source X-ray tube moves through a proscribed arc of excursion Fifteen low-dose projection images are acquired during a 4-second sweep Images are reconstructed into stack of images spaced at 1 mm apart Compression paddle Total dose same as 2D Detector
5 Potential role of DBT in the clinical setting Microcalcifications: FFDM slightly more sensitive than DBT for detection (Spangler ML: AJR 2011;196:320) Demonstrated with equal or greater clarity on DBT (Kopans D: Breast J 2011;17:638) Tumor size assessment: DBT superior to FFDM (Fornvik B: Acta Radiol 2010;51:240) Specificity increased when used adjunctively with FFDM: (Poplack SP: AJR 2007;189:616) (Gur D: AJR 2009;193:586) Mass characterization: Superior cancer visibility and conspicuity (Andersson I: Eur Radiol 2008;18:2817) i.e., DBT might have a great potential in mammography screening!!
6 Tomosynthesis: Potential for increased sensitivity R MLO: 2D (FFDM) R MLO: 3D (Tomosynthesis) Invasive lobular carcinoma (ILC) : 2 mm, gr. 1 ( + LCIS 20 mm and ALH / LCIS ) H,LAB
7 OTST: Cancer left breast a) L MLO: Tomo (3D) L MLO: Tomo (3D) KG170754
8 OTST: Cancer left breast b) L CC: Tomo (3D) L CC: Tomo (3D) KG170754
9 Oslo Tomosynthesis Screening Trial L CC: Conv. FFDM (2D) L CC: Tomosynthesis (3D) b2) Surgical specimen Histology: Radial scar Radiologist A B C D Score (NBCSP) JS040655
10 Images to be included in TOMO screening: One view TOMO only (mlo)? One view 2D (cc) + one view TOMO (mlo)? Two view 2D (mlo + cc) + one view TOMO (mlo)? Two view TOMO (cc + mlo)? Two view 2D (mlo + cc) + two view TOMO (mlo + cc)? Oslo Tomosynthesis Screening Trial: Two view 2D (mlo + cc) + two view TOMO (mlo + cc )
11 Do you see the distortion? b) R MLO: FFDM (2D) R MLO: Tomo (3D) Not so easy on this Tomo MLO view?! HJE150354
12 OTST: Radial scar (+ fibrocystic changes ) c) R CC: FFDM (2D) R CC: Tomo (3D) Radiologist A B C D Score (NBCSP) Distortion obvious on this Tomo CC view! HJE150354
13 Tomosynthesis in breast cancer screening Why do we need 2D (+ TOMO): 2D should maximize mc detection (TOMO: Thin-slice-effect ) Comparison with priors is facilitated if currents includes 2D Externals may request current 2D Experience from experimental clinical studies so far: Two view FFDM 2D (MLO + CC) plus two view TOMO (MLO + CC) is optimal! However: This means a double radiation dose! Synthetic C-Views may substitute for FFDM images (when combined with tomosynthesis) without additional radiation dose!!
14 Synthetic 2D generation: Tomosynthesis reconstructed slices Synthesized Projection Synthetic 2D image (called C-View by Hologic) shows a roadmap of the important features from tomosynthesis slices Synthetic 2D image
15 Synthetic 2D: Synthetic 2D image 2D C-View Tomo L CC L CC L CC
16 Synthetic 2D image Left CC: 2D Left CC: C-View Left CC: Tomo Invasive ductal carcinoma 9 mm
17 Microcalcifications Synthetic 2D image 2D C-view Tomo Synthetic 2D (C-view): Highlighting Tomo: Thin-slice-effect
18 Oslo Tomosynthesis Screening Trial ( OTST ) a) FFDM 2D C-view (Synthetic 2D) L CC L CC DCIS grade 1, > 40 mm
19 Oslo Tomosynthesis Screening Trial: DCIS gr. 1, 40 mm b) 2D C-view Tomo L CC L CC L CC Conventional 2D vs. Synthetic 2D + tomosynthesis
20 Oslo Tomosynthesis Screening Trial (OTST): Invasive ductal carcinoma (IDC) 8 mm Fig. A Fig. B L CC: Synth. 2D (old version) L CC: Synth. 2D (new version «C-View»)
21 ClinicalTrials.gov Tomosynthesis in the Oslo Breast Cancer Screening Program (DBT) ClinicalTrials.gov Identifier: NCT Estimated Enrollment: 25,000 Study Start Date: November 2010 Estimated Primary Completion Date: December 2012 (Final data collection date for primary outcome measure) Oslo Tomosynthesis Screening Trial: Part of the Norwegian Breast Cancer Screening Program Age group years Two-view (CC and MLO) mammography Independent double reading with consensus (arbitration) 5-point rating scale (1=normal/benign; 2-5=positive score) On-line reporting directly into the database of the Norwegian Cancer Registry
22 Oslo Tomosynthesis Screening Trial (OTST) a) Women y. attending the screening unit invited to participate in the OTST, if: * Availability of radiographers * Availability of equipment Excluded: Women with implants Women NOT included: FFDM (2D) only Independent double reading Women included: FFDM (2D) + TOMO (3D) Independent double reading
23 Oslo Tomosynthesis Screening Trial ( OTST ) b) Screening: FFDM (2D) + TOMO (3D) FFDM: Independent double reading FFDM + TOMO: Independent double reading Arm A FFDM: Single reading Arm B FFDM + CAD: Single reading Arm C FFDM + TOMO: Single reading Arm D CompView + TOMO: Single reading Modification of one reading mode for each of the 2 main arm: * One reader Concensus for FFDM / (2D) Arbitration only was meeting offered CAD (Arm B) * One reader for (2D+TOMO) offered synthetic 2D (Arm D) ( for all cases with a score of 2 or higher in at least one arm )
24 Oslo Tomosynthesis Screening Trial ( OTST ) c) Screening: FFDM (2D) + TOMO (3D) FFDM: Independent double reading FFDM + TOMO: Independent double reading Arm A FFDM: Single reading Arm B FFDM + CAD: Single reading Arm C FFDM + TOMO: Single reading Arm D CompView + TOMO: Single reading Concensus / Arbitration meeting ( for all cases with a score of 2 or higher in at least one arm ) Study design: Mainly cancer detection less for specificity (recall)!
25 Indication for tomosynthesis: Dense breast parenchyma Tubular carcinoma 6 mm Screen 2D R MLO Screen TOMO R MLO Reader Arm A B C D Score (NBCSP) D,N130111
26 OTST: Cancer right breast R MLO: 2D R MLO: Tomo (3D) Radiologist A B C D Score (NBCSP) ENH200759
27 Oslo Tomosynthesis Screening Trial: Invasive ductal carcinoma G2, 4.5 mm L MLO: 2D L MLO: Tomo c) Radiologist A B C D Score SN290143
28 050612RLM OTST: Invasive ductal carcinoma (IDC) G1, 10 mm L CC: Conv FFDM (2D) L CC: Synth. 2D (C- View) L CC: Tomosynthesis (3D) Surgical specimen Reader Arm A B C (2D+DBT) D (Synth.2D+DBT) Score (NBCSP)
29 OTST: Batch reading for combo mode (2D FFDM + DBT) Hanging protocol step 1-8 a) Prior CC Prior MLO Current CC dext Current CC sin Current CC Current MLO 1 2 Current MLO dxt Current MLO sin Current FFDM CC dext Current TOMO CC dext 3 4
30 OTST: Batch reading for combo mode (2D FFDM + DBT) Hanging protocol step 1-8 b) Current FFDM MLO dext Current TOMO MLO dext Current FFDM CC sin Current TOMO CC sin 5 6 Current FFDM MLO sin Current TOMO CC sin Prior CC Prior MLO Current CC Current MLO 7 8
31 Mean interpretation time (sec) Mean interpretation time* (sec.) for study arm A D for the 7 radiologists One year Interim analysis Average interpretation time: - Arm A: 45 sec. - Arm C: 91 sec. (Skaane P et al.: Radiology 2013) C = 88 D = 82 B = 58 A = Arm A B C D Radiologist *Outliers (interpretation times < 20 sec. and > 200 sec.) excluded
32 Oslo Tomosynthesis Screening Trial (OTST): First year results * Women 2D + (2D+3D): n = 12, 631 Malignancy: n = 130 Malignancy rate: 1.03% Excl. 10 women with malignancy: - 2 palp. cancer (clin recall) - 3 Interval cancers ( IC ) - 5 Lymphomas/metastases Arm A (2D): n =12,621 Cancers: n = 77 Cancer detection rate: 0.61% Arm C (2D + 3D): n = 12,621 Cancers: n = 101 Cancer detection rate: 0.80% Relative increase in cancer detection ( 2D+TOMO ) vs. ( 2D ): 31% Relative increase in cancer detection: 31% (p< 0.005) * Skaane P et al.: Radiology 2013; 267: 47-56
33 Mammography screening: Comparison of conv. 2D vs. 2D + tomo ( combo )* Parameter Detected with 2D only Detected with combo only Detected with 2D and combo Total with 2D Total with combo Difference combo vs 2D No. cancer Inv. Cancer IDC IDC+DCIS ILC Others Radiol. finding Circ.mass Spicul.mass Distortion Asymm.dens Mc Density+mc DCIS Low grade High grade * Skaane P et al.: Radiology 2013; 267: 47-56
34 Oslo Tomosynthesis Screening Trial : Cancer detection in the 4 arms stratified on the mammographic features Mammographic feature FFDM 2D Arm A Arm B Neg Pos Neg Pos 2D + TOMO Arm C Arm D Neg Pos Neg Pos Double reading A+B C+D Pos Pos Diff. Circumscr. mass Spiculated mass Distortion Asymm. density Calcifications Calc + density Total Arm A: FFDM (2D) Arm B: 2D + CAD Arm C: 2D + Tomosynthesis (3D) Arm D: Synthetic 2D + 3D Relative increase in cancer detection using double reading (2D+TOMO=C+D) vs. (2D=A+B): 32%
35 Oslo Tomosynthesis Screening Trial : Additional cancers detected with combo mode (2D+TOMO) Histology n Grade Mean (mm) Size Range (mm) Inv. ductal carcinoma (IDC) , DCIS , IDC + DCIS , Inv. lobular carcinoma (ILC) * 9,2* 6-15 Tubular carcinoma , Total * 10,7* 3-22 * One ILC without grading and size
36 Tomosynthesis in breast cancer screening: Studies comparing FFDM and Digital Breast Tomosynthesis DBT (August 2013) Study Population ( n ) Study design Examination mode Reading mode Trento/Verona (STORM)1 7,292 Prospective; paired 2D: 2-view 3D: 2-view Double; Sequential Oslo (OTST) 2 12,631 Prospective; paired 2D: 2-view 3D: 2-view Double; Independent TOPS Compr. Breast 3 Center, Houston, TX 2D: 13,856 3D: 9,499 Retrospective; non-paired 2D: 2-view 3D: 2-view Single; Independent Yale University 4 (New Haven, CT) 2D: 7,058 3D: 6,100 Retrospective; non-paired 2D: 2-view 3D: 2-view Single; Independent Malmø (MBTST) 5 5,700 Prospective; paired 2D: 2-view 3D: 1-view Double; Sequential 1) Ciatto S et al.: Lancet Oncol, 2013 (Screening with Tomo OR standard Mammo (STORM)) 2) Skaane P et al.: Eur Radiol, 2013 (Oslo Tomosynthesis Screening Trial OTST) 3) Rose SL et al.: AJR, 2013 (Implementation of breast tomo in a routine screening practice) 4) Haas BM et al.: Radiology, 2013 (Comparison of tomo plus 2D and 2D alone for screening) 5) Zackrisson S: ECR Vienna, 2013 (Interim analysis; Malmø Breast Tomosynthesis Screening Trial)
37 Tomosynthesis in breast cancer screening: Studies comparing FFDM and Digital Breast Tomosynthesis DBT (August 2013) Study Population ( n ) Cancer ( n ) 2D 2D+3D Cancer ( n / 1,000 ) 2D 2D+3D Cancer: Rel. increase ( % ) Trento/Verona (STORM)1 7, % Oslo (OTST) 2 12, % TOPS Compr. Breast 3 Center, Houston, TX Yale University 4 (New Haven, CT) 2D: 13,856 3D: 9,499 2D: 7,058 3D: 6, % 9.5 % Malmø (MBTST) 5 5, % 1) Ciatto S et al.: Lancet Oncol, 2013 (Screening with Tomo OR standard Mammo (STORM)) 2) Skaane P et al.: Eur Radiol, 2013 (Oslo Tomosynthesis Screening Trial OTST) 3) Rose SL et al.: AJR, 2013 (Implementation of breast tomo in a routine screening practice) 4) Haas BM et al.: Radiology, 2013 (Comparison of tomo plus 2D and 2D alone for screening) 5) Zackrisson S: ECR Vienna, 2013 (Interim analysis; Malmø Breast Tomosynthesis Screening Trial)
38 Digital Breast Tomosynthesis (DBT) Conclusions: Tomosynthesis and breast cancer screening Tomosynthesis plus synthesized 2D makes combined 2D and 3D ( combo mode ) possible with approximately the same radiation dose as conventional 2D FFDM Tomosynthesis plus 2D significantly increase the cancer detection rate as compared with 2D FFDM alone The additional interpretation time for tomosynthesis plus 2D ( combo mode ) as compared with 2D alone is acceptable for implementation in organized breast cancer screening Thank you very much for your time! [email protected] Harald Sohlberg ( ): Winter night in Rondane (Norway) (1914)
Hologic Selenia Dimensions C-View Software Module. October 24, 2012
Hologic Selenia Dimensions C-View Software Module October 24, 2012 Introduction and Agenda Peter Soltani, Ph.D. Senior VP & GM, Breast Health Hologic, Inc. Agenda Technology Overview Clinical Overview
Breast Density Legislation: Implications for primary care providers
Breast Density Legislation: Implications for primary care providers Deborah J. Rhodes MD Associate Professor of Medicine 2012 MFMER slide-1 Disclosure Relevant financial relationship(s) None Off-label
Role of the Medical Physicist in Clinical Implementation of Breast Tomosynthesis
Role of the Medical Physicist in Clinical Implementation of Breast Tomosynthesis Bob Liu, Ph.D. Department of Radiology Massachusetts General Hospital And Harvard Medical School Digital Breast Tomosynthesis
Mammography. What is Mammography?
Scan for mobile link. Mammography Mammography is a specific type of breast imaging that uses low-dose x-rays to detect cancer early before women experience symptoms when it is most treatable. Tell your
A Guide to Breast Imaging: The Latest Technology for Screening and Detecting Breast Cancer
A Guide to Breast Imaging: The Latest Technology for Screening and Detecting Breast Cancer Sally Herschorn, MD Associate Professor of Radiology University of Vermont College of Medicine Medical Director
How To Compare Mammography To A 3D System
Radiology Advisory Panel Meeting Hologic Selenia Dimensions 3D System with C-View Software Module FDA Review Robert Ochs, PhD Branch Chief Mammography, Ultrasound, and Imaging Software Branch Division
Breast Imaging Made Brief and Simple. Jane Clayton MD Associate Professor Department of Radiology LSUHSC New Orleans, LA
Breast Imaging Made Brief and Simple Jane Clayton MD Associate Professor Department of Radiology LSUHSC New Orleans, LA What women are referred for breast imaging? Two groups of women are referred for
Personalized Breast Screening Service
Frequently Asked Questions WHAT IS BREAST DENSITY? Breasts are made up of a mixture of fibrous, glandular and fatty tissue. Your breasts are considered if you have predominantly fibrous or glandular tissue
The Principles of Contrast Mammography
The Principles of Contrast Mammography Andrew Smith, Ph.D. Vice President Imaging Science, Hologic Introduction Multiple clinical studies have demonstrated that the use of screening mammography reduces
National Medical Policy
National Medical Policy Subject: Breast Tomosynthesis (Digital), 3-D Mammography Policy Number: NMP 526 Effective Date: December 2013 Update: April 2016 This National Medical Policy is subject to the terms
MAMMOGRAPHY GOALS AND OBJECTIVES
MAMMOGRAPHY GOALS AND OBJECTIVES GOALS: After completion of the mammography rotations, the resident will be able to: 1. Demonstrate learning of the knowledge-based objectives-(practice Base Learning) 2.
Infrared Thermography Not a Useful Breast Cancer Screening Tool
Contact: Jeanne-Marie Phillips Sharon Grutman HealthFlash Marketing The American Society of Breast Surgeons 203-977-3333 877-992-5470 Infrared Thermography Not a Useful Breast Cancer Screening Tool Mammography
Digital Breast Tomosynthesis QC Requirements
Digital Breast Tomosynthesis QC Requirements AAPM Spring Clinical Meeting March 8, 2015 Michael S Glaser, MS, DABR Alliance Medical Physics, LLC Learning Objectives 1. GE SenoClaire - Physicist & Technologist
BREAST IMAGING. Developed by the Ad Hoc Committee on Resident and Fellow Education of the Society of Breast Imaging
BREAST IMAGING Developed by the Ad Hoc Committee on Resident and Fellow Education of the Society of Breast Imaging Stephen A. Feig, M.D., Chair Ferris Hall, M.D. Debra Ikeda, M.D. Ellen Mendelson, M.D.
Digital Breast Tomosynthesis
Digital Breast Tomosynthesis White Paper A clinical assessment based on literature by Dr. Finn Lindhardt, senior consultant, Breast Center Regionshospitalet Viborg June 2010 This article summarizes the
Concepts for High-Resolution Low-Dose CT of the Breast
RSNA 2012 Refresher Course 721B, Chicago, Nov. 30, 2012 Concepts for High-Resolution Low-Dose CT of the Breast Disclosures WAK is founder, shareholder and CEO of CT Imaging GmbH, Erlangen, Germany. Willi
UNITED STATES OF AMERICA FOOD AND DRUG ADMINISTRATION + + + + + + RADIOLOGICAL DEVICES PANEL + + + October 24, 2012 8:00 a.m.
1 1 UNITED STATES OF AMERICA DEPARTMENT OF HEALTH AND HUMAN SERVICES FOOD AND DRUG ADMINISTRATION + + + CENTER FOR DEVICES AND RADIOLOGICAL HEALTH MEDICAL DEVICES ADVISORY COMMITTEE + + + RADIOLOGICAL
How To Write A Draft Report On Breast Cancer Screening
Health Technology Assessment Appropriate Imaging for Breast Cancer Screening in Special Populations Draft Evidence Report: & December 10, 2014 Health Technology Assessment Program (HTA) Washington State
Sustaining a High-Quality Breast MRI Practice
Sustaining a High-Quality Breast MRI Practice Christoph Lee, MD, MSHS Associate Professor of Radiology Adjunct Associate Professor, Health Services University of Washington September 11, 2015 Overview
Breast Ultrasound: Benign vs. Malignant Lesions
October 25-November 19, 2004 Breast Ultrasound: Benign vs. Malignant Lesions Jill Steinkeler,, Tufts University School of Medicine IV Breast Anatomy Case Presentation-Patient 1 62 year old woman with a
Breast Biphasic Compression versus Standard Monophasic Compression in X-ray Mammography 1
Francesco Sardanelli, MD Franco Zandrino, MD Andrea Imperiale, MD Emma Bonaldo, MD Maria G. Quartini, RT Nadia Cogorno, RT Breast Biphasic Compression versus Standard Monophasic Compression in X-ray Mammography
BREAST IMAGING FOR SCREENING AND DIAGNOSING CANCER
MEDICAL POLICY BREAST IMAGING FOR SCREENING AND DIAGNOSING CANCER Policy Number: 2015T0375N Effective Date June 1, 2015 Table of Contents BENEFIT CONSIDERATIONS COVERAGE RATIONALE APPLICABLE CODES.. DESCRIPTION
How To Decide If You Should Get A Mammogram
American Medical Women s Association Position Paper on Principals of Breast Cancer Screening Breast cancer affects one woman in eight in the United States and is the most common cancer diagnosed in women
Breast cancer close to the nipple: Does this carry a higher risk ofaxillary node metastasesupon diagnosis?
Breast cancer close to the nipple: Does this carry a higher risk ofaxillary node metastasesupon diagnosis? Erin I. Lewis, BUSM 2010 Cheri Nguyen, BUSM 2008 Priscilla Slanetz, M.D., MPH Al Ozonoff, Ph.d.
Mammography Education, Inc.
Mammography Education, Inc. 2011 LÁSZLÓ TABÁR, M.D.,F.A.C.R (Hon) 3D image of a milk duct MULTIMODALITY DETECTION and DIAGNOSIS of BREAST DISEASES PRAGUE, Czech Republic Crown Plaza, Prague June 29 - July
Digital Mammography Update: Design and Characteristics of Current Systems
: Design and Characteristics of Current Systems Kalpana M. Kanal, Ph.D., DABR Assistant Professor Department of Radiology University of Washington Seattle, Washington AAPM Annual Meeting 2009 Anaheim,
Nicole Kounalakis, MD
Breast Disease: Diagnosis and Management Nicole Kounalakis, MD Assistant Professor of Surgery Goal of Breast Evaluation The goal of breast evaluation is to classify findings as: normal physiologic variations
Low-dose CT Imaging. Edgar Fearnow, M.D. Section Chief, Computed Tomography, Lancaster General Hospital
Lung Cancer Screening with Low-dose CT Imaging Edgar Fearnow, M.D. Section Chief, Computed Tomography, Lancaster General Hospital Despite recent declines in the incidence of lung cancer related to the
BREAST CHARACTERISTICS AND DOSIMETRIC DATA IN X RAY MAMMOGRAPHY - A LARGE SAMPLE WORLDWIDE SURVEY
BREAST CHARACTERISTICS AND DOSIMETRIC DATA IN X RAY MAMMOGRAPHY - A LARGE SAMPLE WORLDWIDE SURVEY N. GEERAERT a,b,c, R. KLAUSZ a, S. MULLER a, I. BLOCH c, H. BOSMANS b a GE Healthcare, Buc, France b Department
Supports screening, diagnostic, and multimodality workflows
GE Healthcare Universal Viewer Breast Imaging Product Data Sheet Supports screening, diagnostic, and multimodality workflows Introduction Centricity PACS with Universal Viewer 1 puts clinical insight within
Scan Time Reduction and X-ray Scatter Rejection in Dual Modality Breast Tomosynthesis. Tushita Patel 4/2/13
Scan Time Reduction and X-ray Scatter Rejection in Dual Modality Breast Tomosynthesis Tushita Patel 4/2/13 Breast Cancer Statistics Second most common cancer after skin cancer Second leading cause of cancer
Breast Cancer Screening
Breast Cancer Screening Summary of the Clinical Practice Guideline September 2013 These recommendations are systematically developed statements to assist practitioner and patient decisions about appropriate
NOTTINGHAM UNIVERSITY HOSPITAL NHS TRUST NOTTINGHAM BREAST INSTITUTE BREAST AND OVARIAN FAMILY HISTORY GUIDELINES
NOTTINGHAM UNIVERSITY HOSPITAL NHS TRUST NOTTINGHAM BREAST INSTITUTE BREAST AND OVARIAN FAMILY HISTORY GUIDELINES GP Referrals All GP referrals for asymptomatic women with a family history of breast and/or
Low-dose CT for Pulmonary Embolism
Low-dose CT for Pulmonary Embolism Gautham Gautham P. P. Reddy, Reddy, MD, MD, MPH MPH University University of of Washington Washington Introduction Introduction CT CT accounts accounts for for > 50%
Evaluation and Management of the Breast Mass. Gary Dunnington,, M.D. Department of Surgery Internal Medicine Ambulatory Conference December 4, 2003
Evaluation and Management of the Breast Mass Gary Dunnington,, M.D. Department of Surgery Internal Medicine Ambulatory Conference December 4, 2003 Common Presentations of Breast Disease Breast Mass Abnormal
Automated Breast Volume Scanning 3D Ultrasound of the Breast
Automated Breast Volume Scanning 3D Ultrasound of the Breast Roel Mus, MD Radboud University Nijmegen Medical Centre (RUNMC), Nijmegen, The Netherlands Matthieu Rutten, MD, PhD Jeroen Bosch Ziekenhuis,
Guideline for the Imaging of Patients Presenting with Breast Symptoms incorporating the guideline for the use of MRI in breast cancer
Guideline for the Imaging of Patients Presenting with Breast Symptoms incorporating the guideline for the use of MRI in breast cancer Version History Version Date Summary of Change/Process 0.1 09.01.11
Local control in ductal carcinoma in situ treated by excision alone: incremental benefit of larger margins
The American Journal of Surgery 190 (2005) 521 525 George Peter s Award Winner Local control in ductal carcinoma in situ treated by excision alone: incremental benefit of larger margins Heather R. MacDonald,
Ductal Carcinoma In Situ Treated With Breast-Conserving Surgery and Radiotherapy: A Comparison With ECOG Study 5194
Ductal Carcinoma In Situ Treated With Breast-Conserving Surgery and Radiotherapy: A Comparison With ECOG Study 5194 Sabin B. Motwani, MD 1 ; Sharad Goyal, MD 1 ; Meena S. Moran, MD 2 ; Arpit Chhabra, BS
Mammography. For 35+ years, screenfilm has been the gold standard for breast cancer detection
Digital Mammography Upright Stereo Mammography For 35+ years, screenfilm has been the gold standard for breast cancer detection IN THE BEGINNING Mammography technology has come a long way since the first
CONSOLIDATED GUIDANCE ON STANDARDS FOR THE NHS BREAST SCREENING PROGRAMME
CONSOLIDATED GUIDANCE ON STANDARDS FOR THE NHS BREAST SCREENING PROGRAMME NHSBSP Publication No 60 (Version 2) April 2005 Published by: NHS Cancer Screening Programmes The Manor House 260 Ecclesall Road
Ductal Carcinoma in Situ: A Case Report
Ductal Carcinoma in Situ: A Case Report Abstract Breast ductal carcinoma in situ (DCIS) is a preinvasive form of breast cancer and is the most common type of in situ breast cancer found in women. There
Great Strides MARKEY COMPREHENSIVE BREAST CARE CENTER: SETTING A NEW STANDARD OF CARE
Great Strides MARKEY COMPREHENSIVE BREAST CARE CENTER: SETTING A NEW STANDARD OF CARE Markey Cancer Center s Comprehensive Breast Care Center is the first health care provider in Kentucky to offer new
Digital Mammogram National Database
Digital Mammogram National Database Professor Michael Brady FRS FREng Medical Vision Laboratory Oxford University Chairman: Mirada Solutions Ltd PharmaGrid 2/7/03 ediamond aims construct a federated database
PART TWO: DIAGNOSING BREAST CANCER
PART TWO: DIAGNOSING BREAST CANCER What is Breast Cancer? Normal cells can turn into cancer because of genetic inheritance or repeated exposure to a cancer-related substance in the environment, such as
VI. FREQUENTLY ASKED QUESTIONS CONCERNING BREAST IMAGING AUDITS
ACR BI-RADS ATLAS VI. FREQUENTLY ASKED QUESTIONS CONCERNING BREAST IMAGING AUDITS American College of Radiology 55 ACR BI-RADS ATLAS A. All Breast Imaging Modalities 1. According to the BI-RADS Atlas,
im3d S.p.A. La Ricerca fa Impresa
im3d S.p.A. La Ricerca fa 26 gennaio 2011 Alberto Bert Outline Introduction CAD COLON CAD BREAST DTS Introduction La Ricerca fa Who we are and what we do The company im3d S.p.A. is a company developing
Cigna Medical Coverage Policy
Cigna Medical Coverage Policy Subject Screening Mammography Table of Contents Coverage Policy... 1 General Background... 2 Coding/Billing Information... 9 References... 9 Effective Date... 8/23/2016 Next
Stereotactic Breast Biopsy
Scan for mobile link. Stereotactic Breast Biopsy Stereotactic breast biopsy uses mammography a specific type of breast imaging that uses low-dose x-rays to help locate a breast lump or abnormality and
Provincial Quality Management Programs for Mammography, Colonoscopy and Pathology in Ontario
Provincial Quality Management Programs for Mammography, Colonoscopy and Pathology in Ontario Quality Management Partnership Consultation Materials: Mammograp hy October 20, 2014 Table of Contents 1.0 Background
PET/CT-MRI First clinical experience
20 th April 2013, Barcelona, Sp PET/CT-MRI First clinical experience Philippe Appenzeller, MD Staff Radiologist and Nuclear Medicine Physician Department Medical Imaging, University Hospital Zurich PET/CT-MR
MDCT Technology. Kalpana M. Kanal, Ph.D., DABR Assistant Professor Department of Radiology University of Washington Seattle, Washington
MDCT Technology Kalpana M. Kanal, Ph.D., DABR Assistant Professor Department of Radiology University of Washington Seattle, Washington ACMP Annual Meeting 2008 - Seattle, WA Educational Objectives Historical
The File-Card-Browser View for Breast DCE-MRI Data
The File-Card-Browser View for Breast DCE-MRI Data Sylvia Glaßer 1, Kathrin Scheil 1, Uta Preim 2, Bernhard Preim 1 1 Department of Simulation and Graphics, University of Magdeburg 2 Department of Radiology,
Management of Postmenopausal Women with T1 ER+ Tumors: Options and Tradeoffs. Case Study. Surgery. Lumpectomy and Radiation
Management of Postmenopausal Women with T1 ER+ Tumors: Options and Tradeoffs Michael Alvarado, MD Associate Professor of Surgery University of California San Francisco Case Study 59 yo woman with new palpable
OUTLINE OF MAMMOGRAPHY ROTATION GOALS
OUTLINE OF MAMMOGRAPHY ROTATION GOALS Section chief: Haydee Ojeda-Fournier, MD Staff: Drs. Jade de Guzman (JG) and Julie Bykowski (JB) Fellows 2012-13: None Clinic manager: Amy Chatten phone- 858-822-6120
White Paper. Study to Demonstrate Efficacy of 8MP Color Display - Mammography 1.INTRODUCTION... 2 2.PURPOSE... 2 3.METHODS... 2 4.RESULTS...
White Paper Study to Demonstrate Efficacy of 8MP Color Display - Mammography CONTENTS 1.INTRODUCTION... 2 2.PURPOSE... 2 3.METHODS... 2 4.RESULTS... 3 5.CONCLUSIONS... 5 6.REPORT FROM DR. KRUPINSKI, UNIVERSITY
American College of Radiology Mammography Accreditation Program
American College of Radiology Mammography Accreditation Program Objectives Overview of the ACR Mammography Accreditation Program Interrelationship between mammography accreditation, FDA certification and
Needle crystal detector technology in mammography further dose reduction and clinical image quality with
Needle crystal detector technology in mammography further dose reduction and clinical image quality with different beam qualities (W/Rh vs. Mo/Rh) Poster No.: C-1461 Congress: ECR 2013 Type: Scientific
HAVE YOU BEEN NEWLY DIAGNOSED with DCIS?
HAVE YOU BEEN NEWLY DIAGNOSED with DCIS? Jen D. Mother and volunteer. Diagnosed with DCIS breast cancer in 2012. An educational guide prepared by Genomic Health This guide is designed to educate women
Medicare Part B. Mammograms - Updated Billing Guide for Screening and Diagnostic Tests
Mammograms - Updated Billing Guide for Screening and Diagnostic Tests This article from Medicare B News Issue 223 dated October 21, 2005 is being updated and reprinted to ensure that the Noridian Administrative
ACR AAPM SIIM PRACTICE PARAMETER FOR DETERMINANTS OF IMAGE QUALITY IN DIGITAL MAMMOGRAPHY
The American College of Radiology, with more than 30,000 members, is the principal organization of radiologists, radiation oncologists, and clinical medical physicists in the United States. The College
Patient Prep Information
Stereotactic Breast Biopsy Patient Prep Information Imaging Services Cannon Memorial Hospital Watauga Medical Center Table Weight Limits for each facility Cannon Memorial Hospital Watauga Medical Center
INTERDISCIPLINARY CONFERENCE. Florence/Firenze, Italy Nov 27-29, 2012 Centro Congressi al Duomo, Firenze BREAST SEMINAR SERIES
Since breast cancer is not a systemic disease from inception, when the imagers find in situ and 1-14 mm invasive breast cancer, it is the surgeon, specialized in the treatment of breast diseases, who should
Breast Cancer. Sometimes cells keep dividing and growing without normal controls, causing an abnormal growth called a tumor.
Breast Cancer Introduction Cancer of the breast is the most common form of cancer that affects women but is no longer the leading cause of cancer deaths. About 1 out of 8 women are diagnosed with breast
Stomach (Gastric) Cancer. Prof. M K Mahajan ACDT & RC Bathinda
Stomach (Gastric) Cancer Prof. M K Mahajan ACDT & RC Bathinda Gastric Cancer Role of Radiation Layers of the Stomach Mucosa Submucosa Muscularis Serosa Stomach and Regional Lymph Nodes Stomach and Regional
The American College of Radiology Stereotactic Breast Biopsy Accreditation Program: Frequently Asked Questions (Updated: August 24, 2015)
The American College of Radiology Stereotactic Breast Biopsy Accreditation Program: Frequently Asked Questions (Updated: August 24, 2015) Table of Contents Stereotactic Breast Biopsy Accreditation Program
Imaging Informatics Ann Scherzinger, PhD, CIIP C-TRIC Lecture Series, May 18, 2011
Imaging Informatics Ann Scherzinger, PhD, CIIP C-TRIC Lecture Series, May 18, 2011 Science of Information and Information Processing! Breadth, depth of current activities in human medical imaging informatics!
PROPERTY OF ELSEVIER SAMPLE CONTENT - NOT FINAL
Oncoplastic breast conservation surgery Melvin J Silverstein C H A P T E R 5 Introduction Oncoplastic breast conservation surgery combines oncologic principles with plastic surgical techniques. But it
Q.A. Collectible. Sponsored by CRCPD s Committee on Quality Assurance in Diagnostic X-Ray (H-7)
Q.A. Collectible Sponsored by CRCPD s Committee on Quality Assurance in Diagnostic X-Ray (H-7) Mammography Phantom Image Quality Evaluation (from the American College of Radiology 1999 Mammography Quality
Certification protocol for breast screening and breast diagnostic services
Certification protocol for breast screening and breast diagnostic services Authors N. Perry R. Holland M. Broeders H. Rijken M. Rosselli del Turco C. de Wolf This is a revised version of the original EUREF
KIDNEY FUNCTION RELATION TO SIZE OF THE TUMOR IN RENAL CELL CANCINOMA
KIDNEY FUNCTION RELATION TO SIZE OF THE TUMOR IN RENAL CELL CANCINOMA O.E. Stakhvoskyi, E.O. Stakhovsky, Y.V. Vitruk, O.A. Voylenko, P.S. Vukalovich, V.A. Kotov, O.M. Gavriluk National Canсer Institute,
Surgical guidelines for the management of breast cancer
Available online at www.sciencedirect.com EJSO xx (2009) S1eS22 www.ejso.com Guidelines Surgical guidelines for the management of breast cancer Contents Association of Breast Surgery at BASO 2009 Introduction...
Objectives. Mylene T. Truong, MD. Malignant Pleural Mesothelioma Background
Imaging of Pleural Tumors Mylene T. Truong, MD Imaging of Pleural Tumours Mylene T. Truong, M. D. University of Texas M.D. Anderson Cancer Center, Houston, TX Objectives To review tumors involving the
Coronis 5MP Mammo. The standard of care for digital mammography
Coronis 5MP Mammo The standard of care for digital mammography The standard of care For thousands of women every day, details make all the difference. This understanding, along with many years of commitment
PRACTICAL TIPS IN ENSURING RADIATION SAFETY IN THE USE OF MEDICAL DIAGNOSTIC X-RAY EQUIPMENT
PRACTICAL TIPS IN ENSURING RADIATION SAFETY IN THE USE OF MEDICAL DIAGNOSTIC X-RAY EQUIPMENT Although the medical uses of X-rays to examine a patient without surgery became an amazing medical breakthrough,
La Chemioterapia Adiuvante Dose-Dense. Lo studio GIM 2. Alessandra Fabi
La Chemioterapia Adiuvante Dose-Dense Lo studio GIM 2 Alessandra Fabi San Antonio Breast Cancer Symposium -December 10-14, 2013 GIM 2 study Epirubicin and Cyclophosphamide (EC) followed by Paclitaxel (T)
MQSA and ACR Digital Breast Tomosynthesis Mammography Accreditation
US FFDM Mammography Facilities and Units MQSA and ACR Digital Breast Tomosynthesis Mammography Accreditation Pamela L. Platt, BSRT(R)(M)(CV) FDA Liaison, ACR Breast Imaging Accreditation Program In 2000
Preprocessing of Screening Mammograms Based on Local Statistical Models
Preprocessing of Screening Mammograms Based on Local Statistical Models Jiří Grim Institute of Information Theory and Automation Czech Academy of Sciences P.O. BOX 18, 18208 Prague 8 Czech Republic [email protected]
Breast Screening Explained. We can supply this information in other languages, in large print, on audio or in Braille.
Breast Screening Explained We can supply this information in other languages, in large print, on audio or in Braille. Breast Screening Explained This leaflet tells you about free breast screening. Breast
Purchasing a cardiac CT scanner: What the radiologist needs to know
Purchasing a cardiac CT scanner: What the radiologist needs to know Maria Lewis ImPACT St George s Hospital, London [email protected] CT scanner development Slice wars 1998 Increased z-coverage
BREAST IMAGING SOLUTIONS. Integrated Breast Imaging Workflow Solutions
BREAST IMAGING SOLUTIONS Integrated Breast Imaging Workflow Solutions Seamless Workflow Solutions Customized to Your Needs Hologic understands that a well structured connectivity plan benefits your whole
Should I Continue Having Mammograms to Screen for Breast Cancer? A decision aid for women aged 70 and older at their next screening mammogram.
Should I Continue Having Mammograms to Screen for Breast Cancer? A decision aid for women aged 70 and older at their next screening mammogram. AUSTRALIAN SCREENING MAMMOGRAPHY DECISION AID TRIAL Why is
Breast Cancer Screening 101:
Breast Cancer Screening 101: Screening Guidelines and Imaging Modalities Robert Smith, PhD American Cancer Society Cheryl Herman, MD NAPBC Education Committee November 23, 2015 Webinar Topics - Burden