M. Ravaioli, M.D., PhD

Size: px
Start display at page:

Download "M. Ravaioli, M.D., PhD"

Transcription

1 Quale è il futuro dei trapianti di organo solido? Con la bioingegneria e l utilizzo di cellule staminali potremo curare meglio le insufficienze d organo e di tessuto? M. Ravaioli, M.D., PhD Department of General Surgery and Transplantation Prof. AD Pinna Policlinico Sant Orsola Malpighi University of Bologna, Italy

2 Il fegato artificiale impiantabile? By-pass but not liver available to transplantation Use of partial cardiopulmonary bypass during the anhepatic phase of orthotopic liver grafting. Lancet 1979 R.Y. Calne Venous Bypass in Clinical Liver Transplantation B.W. Shaw Ann Surg 1984

3 Il fegato artificiale impiantabile?

4 European gap among donors and recipients Extended criteria donors Living donors Candidates to Liver or Kidney Tx Split NHBD Deceased donors available Domino Effective allocation system

5 Extended criteria liver = Artificial liver?

6 Extended criteria donors Graft with an increased risk of early failure or inferior graft and patient survival resulting from per-transplant factors Extended Criteria Donor/Graft = ECD

7 MELD era, ECD and

8 Balance among: MELD era, ECD and Marginal graft MELD Recipient Selective criteria MELD era Pre-MELD era Quality transplant programs

9 Liver transplantation strategies from Kidney experience 1-3 hours Liver biopsy Expert pathologists on liver disease available 24 hours per day at our hospital Donor aorta clamped Recipient on the operating room Decision to accept the liver: senior surgeons considers the histological assessment and the macroscopic aspect as depicted by the harvesting surgeon 30 minutes Histo-pathological report by telephone

10 Liver transplantation strategies from Kidney experience Dissection Hepatectomy Transplantation Increased graft ischemia

11 Liver transplantation strategies from Kidney experience Dissection Hepatectomy Transplantation Short graft ischemia

12 Liver transplantation strategies from Kidney experience Ravaioli et al.transplant International 2009

13 Surgical Techniques To-day and To-morrow How to improve outcome of E.C.D. different form partial grafts?

14 ECD, other strategies to improve the outcome?

15 ECD, other strategies to improve the outcome?

16 ECD, other strategies to improve the outcome? Transplantation of high-risk donor lungs that were physiologically stable during 4 hours of ex vivo perfusion led to results similar to those obtained with conventionally selected lungs

17 ECD, other strategies to improve the outcome? Static Ice System Simple, reproducible technique Inexpensive Few supply needs Little technical expertise needed Allows for easy long distance transportation Acceptable immediate function rates with short ischemic times Pulsatile Perfusion More complicated to set up More expensive Need machine, perfusion cassette and liquid especially design Technical expertise Provides a monitoring capability Allows transportation

18 ECD, other strategies to improve the outcome? Flow effects on the endothelial cell Kamm R, Annu. Rev. Fluid Mech Endothelial cells under no-flow conditions (a) and after exposure to 1.2 Pa of steady, laminar shear stress for 24 h (b).

19 Machine Perfusion or Cold Storage in Deceased-Donor Kidney Transplantation

20 Machine Perfusion or Cold Storage in Deceased-Donor Kidney Transplantation

21 Machine Perfusion or Cold Storage in Deceased-Donor Kidney Transplantation DGF 70 pts machine-perfusion group vs. 89 cold-storage group (P = 0.01) One-year allograft survival was superior in the machine-perfusion group (94% vs. 90%, P = 0.04)

22 ECD, other strategies to improve the outcome?

23 ECD, other strategies to improve the outcome? Infusion fluids Organ chamber Venous Reservoir Membrane oxygenator Centrifugal Pump Urinometer Temperature probe

24 ECD, other strategies to improve the outcome?

25 ECD, other strategies to improve the outcome? The delayed graft function rate (DGF), defined as the requirement for dialysis within the first 7 days 1/18 (5.6%) EVNP group vs. 17/47 (36.2%) CS group p = There was no difference in graft or patient survival at 12 months

26 ECD, other strategies to improve the outcome?

27 ECD, other strategies to improve the outcome? steatotic livers can be successfully preserved using normothermic preservation for prolonged periods and that normothermic preservation facilitates a reduction in hepatic steatosis

28 ECD, other strategies to improve the outcome?

29 ECD, other strategies to improve the outcome?

30 ECD, other strategies to improve the outcome?

31 ECD, other strategies to improve the outcome?

32 ECD, other strategies to improve the outcome?

33 ECD, other strategies to improve the outcome? 20 LTs HMP preserved vs. 20 a matched group transplanted with CS livers Early allograft dysfunction Rates were 5%in the HMP group versus 25% in controls (p = 0.08)

34 ECD, other strategies to improve the outcome? Donors after cardiac death (DCD) maintain with normothermic extracorporeal membrane oxygenation (NECMO)

35 ECD, other strategies to improve the outcome?

36 ECD, other strategies Bologna researches..

37 ECD, other strategies Bologna researches..

38 ECD, other strategies Bologna researches..

39 ECD, other strategies Bologna researches..

40 ECD, other strategies Bologna researches.. T-0 T-1 T-2

41 Surgical Techniques To-day and To-morrow How will be future grafts?

42 Surgical Techniques To-day and To-morrow

43 Surgical Techniques To-day and To-morrow

44 Prospective fellows whom I trained in this field went on to pass on what we have learned to date from our research, not only as it applies to transplantation per se, but also to its broader implications for medicine as a whole

45 Conclusions: support donation and living donors

The Current State of Organ Procurement

The Current State of Organ Procurement The Current State of Organ Procurement Sue Dunn President & CEO Colorado Center for Transplantation Care, Research and Education Wednesday, March 7, 2012 Who is Donor Alliance? Organ Procurement Organization

More information

*6816* 6816 CONSENT FOR DECEASED KIDNEY DONOR ORGAN OPTIONS

*6816* 6816 CONSENT FOR DECEASED KIDNEY DONOR ORGAN OPTIONS The shortage of kidney donors and the ever-increasing waiting list has prompted the transplant community to look at different types of organ donors to meet the needs of our patients on the waiting list.

More information

Deceased-Donor Renal Transplant Information for patients

Deceased-Donor Renal Transplant Information for patients Deceased-Donor Renal Transplant Information for patients Exceptional healthcare, personally delivered As part of the work-up for the NHS Blood and Transplant (NHSBT) kidney transplant waiting list, you

More information

Living Donor Liver Transplantation

Living Donor Liver Transplantation Revised March 2012 Living Donor Liver Transplantation American Society of Transplantation 1120 Route 73, Suite 200 Mount Laurel, NJ 08054 Phone: 856-439-9986 Fax: 856-439-9982 E-mail: info@myast.org The

More information

Liver transplantation: The Spanish experience

Liver transplantation: The Spanish experience Digestive and Liver Disease Supplements 3 (2009) 75 81 www.elsevier.com/locate/dld Liver transplantation: The Spanish experience R. Matesanz *, G. de la Rosa National Transplant Organization (ONT), Madrid,

More information

ASTS Handy Guide on Professional Coding

ASTS Handy Guide on Professional Coding ASTS Handy Guide on Professional Coding Dear Colleagues, The ASTS Reimbursement Committee is happy to provide you with this handy guide for transplant surgery professional coding from the 2012 Current

More information

Expanded Criteria Donor: Revisited? Bryce Kiberd

Expanded Criteria Donor: Revisited? Bryce Kiberd Expanded Criteria Donor: Revisited? Bryce Kiberd Overall AIM of ECD Policy Increase organ utilization Objectives Review the definitions of ECD ECD allocation options Evidence supporting the use ECD Definition

More information

LIVER TRANSPLANTATION Update on Allocation Living Donor Liver Tx.

LIVER TRANSPLANTATION Update on Allocation Living Donor Liver Tx. LIVER TRANSPLANTATION Update on Allocation Living Donor Liver Tx. Steven L. Flamm MD Associate Professor of Medicine Medical Director, Liver Transplantation Northwestern University Medical School 1958

More information

Ambulatory ECMO. Don Hayes, Jr., MD, MS Section of Pulmonary Medicine Nationwide Children's Hospital The Ohio State University

Ambulatory ECMO. Don Hayes, Jr., MD, MS Section of Pulmonary Medicine Nationwide Children's Hospital The Ohio State University Ambulatory ECMO Don Hayes, Jr., MD, MS Section of Pulmonary Medicine Nationwide Children's Hospital The Ohio State University Disclosures No conflicts of interest No financial relationships Funding

More information

Ch. 158 VITAL ORGAN TRANSPLANTATION SERVICES 28 158.1 CHAPTER 158. VITAL ORGAN TRANSPLANTATION SERVICES GENERAL PROVISIONS

Ch. 158 VITAL ORGAN TRANSPLANTATION SERVICES 28 158.1 CHAPTER 158. VITAL ORGAN TRANSPLANTATION SERVICES GENERAL PROVISIONS Ch. 158 VITAL ORGAN TRANSPLANTATION SERVICES 28 158.1 CHAPTER 158. VITAL ORGAN TRANSPLANTATION SERVICES Sec. 158.1. Principle. 158.2. Definitions. 158.3. Scope. GENERAL PROVISIONS PROGRAM, SERVICE AND

More information

Where Will my New Kidney Come From?

Where Will my New Kidney Come From? Where Will my New Kidney Come From? The Organ Shortage There is a severe shortage of organs for transplant. This means that the wait for a kidney transplant can be many years. The UW Transplant Program

More information

LIVING LIVER DONOR INITIAL CONSENT FOR EVALUATION

LIVING LIVER DONOR INITIAL CONSENT FOR EVALUATION LIVING LIVER DONOR INITIAL CONSENT FOR EVALUATION I am thinking about donating a part of my liver to a patient who has end stage liver disease. This patient s doctors have decided that the best treatment

More information

Kidney and Pancreas Transplant Evaluation Clinics and Committee: Inpatient Nephrology Transplant Consult Service

Kidney and Pancreas Transplant Evaluation Clinics and Committee: Inpatient Nephrology Transplant Consult Service Care of Renal Transplant Patients takes place in five distinct practice settings at the University of Michigan: a) Kidney and Pancreas Pre-transplant evaluation clinics (five half-day clinics per week)

More information

Wake Forest School of Medicine Department of General Surgery

Wake Forest School of Medicine Department of General Surgery Wake Forest School of Medicine Department of General Surgery TRANSPLANT SURGERY RESIDENT CURRICULUM (PGY-3) OVERVIEW This curriculum has largely been adapted from the curriculum for transplant surgery

More information

TransplantUpdate. A Report From Baylor Regional Transplant Institute Volume 2 Number 1

TransplantUpdate. A Report From Baylor Regional Transplant Institute Volume 2 Number 1 TransplantUpdate A Report From Baylor Regional Transplant Institute Volume 2 Number 1 Treatment of Ascites 2 Ascites the accumulation of fluid in the abdominal cavity is the most common complication of

More information

Factors Affecting Outcomes for Kidney Transplant Recipients

Factors Affecting Outcomes for Kidney Transplant Recipients Factors Affecting Outcomes for Kidney Transplant Recipients Alden Doyle, MD, MS, MPH Associate Professor of Medicine Medical Director of Kidney and Pancreas Transplantation Drexel University/Hahnemann

More information

LUNG TRANSPLANT SURGERY AND HOSPITAL STAY. The Call Lung(s) Transplant is Available for You. Bring to the Hospital

LUNG TRANSPLANT SURGERY AND HOSPITAL STAY. The Call Lung(s) Transplant is Available for You. Bring to the Hospital LUNG TRANSPLANT SURGERY AND HOSPITAL STAY The Call Lung(s) Transplant is Available for You The call for lung(s) transplant can come any time, day or night. The transplant coordinator will ask you some

More information

By Sally Pobojewski Illustration by ann cutting. Medicine at Michigan

By Sally Pobojewski Illustration by ann cutting. Medicine at Michigan Fifty years ago, U-M surgeon Robert Bartlett helped invent a life-saving procedure called Extracorporeal Membrane Oxygenation (ECMO). Now researchers are using the next-generation of ECMO to give lungs

More information

so good that so many people want a liver transplant. And if you look at what that means across the

so good that so many people want a liver transplant. And if you look at what that means across the LIVING DONOR LIVER TRANSPLANT, ABHI HUMAR, MD 1 The topic today is live donor liver transplant and I d start this by saying that liver transplantation is really a victim of its own success. We ve gotten

More information

Laparoscopic Donor Nephrectomy (donating a kidney to a friend or family member who needs a kidney transplant)

Laparoscopic Donor Nephrectomy (donating a kidney to a friend or family member who needs a kidney transplant) Laparoscopic Donor Nephrectomy (donating a kidney to a friend or family member who needs a kidney transplant) A simple guide to help answer your questions What are your kidneys? The kidneys are two fist-sized

More information

INTERDISCIPLINARY CLINICAL MANUAL Policy & Procedure

INTERDISCIPLINARY CLINICAL MANUAL Policy & Procedure INTERDISCIPLINARY CLINICAL MANUAL Policy & Procedure TITLE: Organ and Tissue Donation NUMBER: CC 90-045 Section: Special Procedures Date Issued: October 2007 Source: Distribution: MAC Sub Committee Organ

More information

Information on Organ Donation and Transplantation in Ireland

Information on Organ Donation and Transplantation in Ireland Information on Organ Donation and Transplantation in Ireland The Gift of Life The decision to donate a loved one s organs is often made at a time of profound loss and sadness. However this act of generosity

More information

Transplant Coordinator

Transplant Coordinator Have you signed your organ donor card? Hearts, kidneys, livers, and lungs can all be transplanted. When you die, one of your organs could help a critically ill patient live a longer life. What I do every

More information

Living Donor Liver Transplantation. Kyung-Suk Suh, M.D. Department of Surgery, Seoul National University College of Medicine

Living Donor Liver Transplantation. Kyung-Suk Suh, M.D. Department of Surgery, Seoul National University College of Medicine Living Donor Liver Transplantation Kyung-Suk Suh, M.D. Department of Surgery, Seoul National University College of Medicine Liver Transplantation in Korea 700 118 600 64 66 500 400 37 28 50 480 530 559

More information

MELD System: Past and Present. Patrick S. Kamath, MD Mayo Clinic College of Medicine Division of Gastroenterology and Hepatology

MELD System: Past and Present. Patrick S. Kamath, MD Mayo Clinic College of Medicine Division of Gastroenterology and Hepatology MELD System: Past and Present Patrick S. Kamath, MD Mayo Clinic College of Medicine Division of Gastroenterology and Hepatology MELD for Liver Transplantation: Outline What is the MELD Score? Why was liver

More information

Medicine & Emergency Department Pre-transplantation decisions and preparation

Medicine & Emergency Department Pre-transplantation decisions and preparation Medicine & Emergency Department Pre-transplantation decisions and preparation Information for renal patients Who can have a kidney transplant? Kidney transplantation is the preferred choice of treatment

More information

Frequently Asked Questions For Waitlisted Patients

Frequently Asked Questions For Waitlisted Patients Frequently Asked Questions For Waitlisted Patients Questions About My Follow-up On the Waitlist Q: How long will I have to wait for a new kidney? Wait time for a donor organ is dependent upon several factors.

More information

Birmingham Children s Hospital NHS Foundation Trust. Living Donor Liver Transplantation. Patient information

Birmingham Children s Hospital NHS Foundation Trust. Living Donor Liver Transplantation. Patient information Birmingham Children s Hospital NHS Foundation Trust Living Donor Liver Transplantation Patient information Information for donors This leaflet provides information to potential donors, families and recipients

More information

Liver Transplant. Liver Transplant Payment Policy Policy number M.TSO , effective 03/01/2013. Page 1

Liver Transplant. Liver Transplant Payment Policy Policy number M.TSO , effective 03/01/2013. Page 1 Liver Transplant I. Policy University Health Alliance (UHA) will reimburse for a liver transplant when it is determined to be medically necessary and when it meets the medical criteria guidelines (subject

More information

6/22/2013. Mechanical Support of the Right Ventricle in Children with Pulmonary Hypertensive Vascular Disease. No conflicts to disclose

6/22/2013. Mechanical Support of the Right Ventricle in Children with Pulmonary Hypertensive Vascular Disease. No conflicts to disclose Mechanical Support of the Right Ventricle in Children with Pulmonary Hypertensive Vascular Disease 6 th International Conference Neonatal & Childhood Pulmonary Vascular Disease San Francisco, California

More information

New UNOS Kidney Allocation System (KAS)

New UNOS Kidney Allocation System (KAS) New UNOS Kidney Allocation System (KAS) UNOS: United Network for Organ Sharing OPTN: Organ Procurement and Transplantation Network Lee Ann, Baxter-Lowe, Ph.D. The content is the responsibility of the authors

More information

Management of Liver Cancer: In the Era of Liver Transplantation

Management of Liver Cancer: In the Era of Liver Transplantation Management of Liver Cancer: In the Era of Liver Transplantation Marwan S. Abouljoud, M.D., F.A.C.S. Benson Ford Chair Transplant and Hepatobiliary Surgery Director, Henry Ford Transplant Institute I have

More information

Bachelor of Science Cardiovascular Perfusion

Bachelor of Science Cardiovascular Perfusion Bachelor of Science What do Perfusionists do? Perfusionists are highly trained specialists who manage the cardiopulmonary physiology of patients requiring extracorporeal support. That is, they use specialized

More information

ACGME Program Requirements for Graduate Medical Education in Pediatric Nephrology

ACGME Program Requirements for Graduate Medical Education in Pediatric Nephrology ACGME Program Requirements for Graduate Medical Education in Pediatric Nephrology ACGME approved: June 10, 2008; effective: July 1, 2009 ACGME approved focused revision: September 30, 2012; effective:

More information

Donor Kidney Recovery Methods and the Incidence of Lymphatic Complications in Kidney Transplant Recipients

Donor Kidney Recovery Methods and the Incidence of Lymphatic Complications in Kidney Transplant Recipients Donor Kidney Recovery Methods and the Incidence of Lymphatic Complications in Kidney Transplant Recipients The Harvard community has made this article openly available. Please share how this access benefits

More information

Appendix G - Identification and Selection of Studies

Appendix G - Identification and Selection of Studies FINAL Emergency framework for rationing of blood for massively bleeding patients during a red phase of a Appendix G - Identification and Selection of Studies Inclusion/Exclusion Criteria We included studies

More information

8/12/2016. HEART TRANSPLANTATION: Past, Present, and Future CARDIAC TRANSPLANTATION TOM ESTEP, MD HEART TRANSPLANT SURGEON

8/12/2016. HEART TRANSPLANTATION: Past, Present, and Future CARDIAC TRANSPLANTATION TOM ESTEP, MD HEART TRANSPLANT SURGEON HEART TRANSPLANTATION: Past, Present, and Future TOM ESTEP, MD HEART TRANSPLANT SURGEON CARDIAC TRANSPLANTATION 1 HISTORY 1900 S: CARREL AND GUTHRIE HETEROTOPIC TRANSPLANT 1951: FIRST ORTHOTOPIC CARDIAC

More information

Talking About Living Kidney Donation with Family and Friends

Talking About Living Kidney Donation with Family and Friends Talking About Living Kidney Donation with Family and Friends Purpose of this guide Y ou may be a person who has kidney disease. Perhaps you know someone with kidney disease. Talking about kidney disease

More information

FREQUENTLY ASKED QUESTIONS ORGAN DONATION NHS BLOOD AND TRANSPLANT

FREQUENTLY ASKED QUESTIONS ORGAN DONATION NHS BLOOD AND TRANSPLANT FREQUENTLY ASKED QUESTIONS ORGAN DONATION NHS BLOOD AND TRANSPLANT Would you take an organ if you needed one? Nearly everyone would. But only 32% of the UK population have joined the NHS Organ Donor Register.

More information

Living Donor Paired Exchange Registry. What is Living Kidney Donor Paired Exchange?

Living Donor Paired Exchange Registry. What is Living Kidney Donor Paired Exchange? Living Paired Exchange Registry What is Living Kidney Paired Exchange? The Living Paired Exchange Registry. At Canadian Blood Services, we are committed to helping Canadians help each other. By building

More information

HYPOPLASTIC LEFT HEART SYNDROME

HYPOPLASTIC LEFT HEART SYNDROME HYPOPLASTIC LEFT HEART SYNDROME What is HLHS? HLHS is the one of the most challenging and complex form of congenital heart diseases. Without treatment, this defect is usually fatal within the first weeks

More information

For survival probabilities, first transplant, see Section I: Patient Survival

For survival probabilities, first transplant, see Section I: Patient Survival F transpl antation: ou tcomes ftransplantation: outcomes For survival probabilities, first transplant, see Section I: Patient Survival 144 F.1. 145 90-day graft survival probabilities: all deceased donor

More information

TA L K I N G A B O U T T R A N S P L A N TAT I O N

TA L K I N G A B O U T T R A N S P L A N TAT I O N TA L K I N G A B O U T T R A N S P L A N TAT I O N Who are UNOS and the OPTN? United Network for Organ Sharing (UNOS) is a non-profit charitable organization that manages the nation s transplant system

More information

Chapter 4 Section 24.2

Chapter 4 Section 24.2 Surgery Chapter 4 Section 24.2 Issue Date: December 11, 1986 Authority: 32 CFR 199.4(e)(5) 1.0 CPT 1 PROCEDURE CODES 33940-33945, 33975-33980 2.0 POLICY 2.1 Benefits are allowed for heart transplantation.

More information

The New Kidney Allocation System: Resources for Protocols and Processes webinar.

The New Kidney Allocation System: Resources for Protocols and Processes webinar. The New Kidney Allocation System: Resources for Protocols and Processes webinar. 1 Speakers for the webinar are: Dr. Richard Formica Associate Professor of Medicine and Surgery, Yale University School

More information

LOPA Orientation Plan Organ Recovery Coordinator I/II Table of Contents

LOPA Orientation Plan Organ Recovery Coordinator I/II Table of Contents Orientation Plan Overview Phase I-Referral Process I. Definition II. Expectations III. Policies IV. Training Documentation LOPA Orientation Plan Organ Recovery Coordinator I/II Table of Contents Phase

More information

DO I BECOME A LIVING ORGAN DONOR FOR MY SICK RELATIVE?

DO I BECOME A LIVING ORGAN DONOR FOR MY SICK RELATIVE? DO I BECOME A LIVING ORGAN DONOR FOR MY SICK RELATIVE? Supporting decision making in adult-to-adult living liver donation Justyna Bartoszko, Alexandra Shingina, Dr. Girish Kulkarni Institute of Health

More information

The organ shortage is a preeminent issue in the current era

The organ shortage is a preeminent issue in the current era Outcomes of Dual Adult Kidney Transplants in the United States: An Analysis of the OPTN/UNOS Database Jagbir Gill, 1 Yong W. Cho, 2 Gabriel M. Danovitch, 1 Alan Wilkinson, 1 Gerald Lipshutz, 1 Phuong-Thu

More information

Overview of Organ Donation and Transplantation

Overview of Organ Donation and Transplantation 2 Overview of Organ Donation and Transplantation Overview of Organ Donation and Transplantation A summary of organ donation and transplantation activity in the UK during the financial year from 1 April

More information

FFR and CABG Emanuele Barbato, MD, PhD, FESC Cardiovascular Center Aalst, Belgium

FFR and CABG Emanuele Barbato, MD, PhD, FESC Cardiovascular Center Aalst, Belgium FFR and CABG Emanuele Barbato, MD, PhD, FESC Cardiovascular Center Aalst, Belgium Background 8 th Coronary Physiology in the CathLab Course Revascularisation of intermediate stenosis can be targeted EITHER

More information

Thoracoabdominal aortic aneurysm

Thoracoabdominal aortic aneurysm Thoracoabdominal aortic aneurysm Patient (1) - 69 PMH: 2013 - MVP, aortic root replacement with biological valve (Perimount) and subtotal aortic arch replacement Analysis for oppressive chest complaints

More information

David Axelrod, MD, MBA Associate Professor of Surgery Section Chief Solid Organ Transplantation Dartmouth Hitchcock Medical Center

David Axelrod, MD, MBA Associate Professor of Surgery Section Chief Solid Organ Transplantation Dartmouth Hitchcock Medical Center David Axelrod, MD, MBA Associate Professor of Surgery Section Chief Solid Organ Transplantation Dartmouth Hitchcock Medical Center Economic analysis team Mark Schnitzler, Ph.D. Krista Lentine MD, Ph.D.

More information

New Kidney Allocation and What it Means to Your Transplant Center and Your Patients

New Kidney Allocation and What it Means to Your Transplant Center and Your Patients New Kidney Allocation and What it Means to Your Transplant Center and Your Patients Alexander Wiseman, M.D. Professor, Division of Renal Diseases and Hypertension Medical Director, Kidney and Pancreas

More information

The VeriQ system for assessing graft flow during coronary artery bypass graft surgery

The VeriQ system for assessing graft flow during coronary artery bypass graft surgery The VeriQ system for assessing graft flow during coronary artery bypass graft surgery Implementing NICE guidance November 2011 NICE medical technology guidance 8 What this presentation covers Background

More information

The European experience

The European experience Transplant International ISSN 934-874 REVIEW The European experience Leo Roels 1 and Axel Rahmel 2 1 Donor Action Foundation, Linden, Belgium 2 Eurotransplant International Foundation, Leiden, The Netherlands

More information

ELSO GUIDELINES FOR ECMO CENTERS

ELSO GUIDELINES FOR ECMO CENTERS ELSO GUIDELINES FOR ECMO CENTERS PURPOSE These guidelines developed by the Extracorporeal Life Support Organization, outline the ideal institutional requirements needed for effective use of extracorporeal

More information

POTENTIAL LIVING LIVER DONOR CANDIDATES CAN HAVE SIMPLE NEW SCREENING TESTS

POTENTIAL LIVING LIVER DONOR CANDIDATES CAN HAVE SIMPLE NEW SCREENING TESTS Media Contact:Diane Shnitzler (703) 691-1805 10201 Lee Highway Suite 500 Fairfax, Virginia 22030 703.691.1805 703.691.1855 fax www.sirweb.org info@sirweb.org For release Tuesday, March 6, 2001 AT A GLANCE

More information

GUIDELINE. Cadaveric Organ and Tissue Donation and Transplantation

GUIDELINE. Cadaveric Organ and Tissue Donation and Transplantation GUIDELINE Cadaveric Organ and Tissue Donation and Transplantation Purpose The purpose of this guideline is to support ethical and clinically consistent, effective and safe organ and tissue donation for

More information

Saint Francis Kidney Transplant Program Issue Date: 6/9/15

Saint Francis Kidney Transplant Program Issue Date: 6/9/15 Kidney Transplant Candidate Informed Consent Education Here are educational materials about Kidney Transplant. Please review and read these before your evaluation visit. The RN Transplant Coordinator will

More information

Mohamed Akoad, MD, FACS Chair, Department of Transplantation Alicia Parrott, RN Living Donor Nurse Coordinator

Mohamed Akoad, MD, FACS Chair, Department of Transplantation Alicia Parrott, RN Living Donor Nurse Coordinator Mohamed Akoad, MD, FACS Chair, Department of Transplantation Alicia Parrott, RN Living Donor Nurse Coordinator Living Donor Liver Transplantation is a surgical innovation that has been developed to address

More information

ADULT-TO-ADULT LIVING DONOR LIVER TRANSPLANTATION COHORT STUDY

ADULT-TO-ADULT LIVING DONOR LIVER TRANSPLANTATION COHORT STUDY ADULT-TO-ADULT LIVING DONOR LIVER TRANSPLANTATION COHORT STUDY Enclosed please find a synopsis of the A2ALL Cohort study and summaries of the following sub-studies: Restoration of Hepatic Function in Living

More information

renal transplantation: A single-center comparative study

renal transplantation: A single-center comparative study Impact of posterior urethral valves on pediatric renal transplantation: A single-center comparative study BY Mohamed Kamal Gheith, MD Oberarzt die Urologie, Universitätsmedizin Mainz Ass. Prof. of Urology,

More information

Kidney Transplant. If you have questions or would like more. information about Cleveland Clinic s. Kidney Transplant Program, please call us

Kidney Transplant. If you have questions or would like more. information about Cleveland Clinic s. Kidney Transplant Program, please call us Kidney Transplant Guide for recipients and donors In 1963, Cleveland Clinic performed the first kidney transplant in Northeast Ohio and became a recognized pioneer in the field of organ transplantation.

More information

How does a kidney transplant differ from dialysis?

How does a kidney transplant differ from dialysis? TA L K I N G A B O U T T R A N S P L A N TAT I O N Frequently Asked Questions about Kidney Transplant Evaluation and Listing If your kidneys have stopped working properly, or may stop working soon, you

More information

Living Donor Liver Transplant. An information guide for donors and recipients

Living Donor Liver Transplant. An information guide for donors and recipients Living Donor Liver Transplant An information guide for donors and recipients Table of Contents Page Number About Transplantation at Johns Hopkins 2 Liver Transplantation 2 Contact Us 2 Living Donor Transplant

More information

Catheter insertion of a new aortic valve to treat aortic stenosis

Catheter insertion of a new aortic valve to treat aortic stenosis Issue date March 2012 Understanding NICE guidance Information for people who use NHS services NICE interventional procedures guidance advises the NHS on when and how new procedures can be used in clinical

More information

Facing Coronary Artery Bypass Surgery? Learn about minimally invasive da Vinci Surgery

Facing Coronary Artery Bypass Surgery? Learn about minimally invasive da Vinci Surgery Facing Coronary Artery Bypass Surgery? Learn about minimally invasive da Vinci Surgery The Condition: Coronary Artery Disease Coronary artery disease is a form of heart disease that affects your arteries.

More information

What is a Living Will?

What is a Living Will? What is a Living Will? With today s advances in medical technology, the process of dying can be prolonged by what are often referred to as artificial means. A Living Will can be used to let your healthcare

More information

AUSTRALIAN DONATION AND TRANSPLANTATION ACTIVITY REPORT 2015

AUSTRALIAN DONATION AND TRANSPLANTATION ACTIVITY REPORT 2015 AUSTRALIAN DONATION AND TRANSPLANTATION ACTIVITY REPORT 215 Australia achieved its highest ever donation and transplantation outcomes in 215. Last year, a record 1,241 lives were saved and transformed

More information

Children's Medical Services (CMS) Regional Perinatal Intensive Care Center (RPICC) Neonatal Extracorporeal Life Support (ECLS) Centers Questionnaire

Children's Medical Services (CMS) Regional Perinatal Intensive Care Center (RPICC) Neonatal Extracorporeal Life Support (ECLS) Centers Questionnaire Children's Medical Services (CMS) Regional Perinatal Intensive Care Center (RPICC) Neonatal Extracorporeal Life Support (ECLS) Centers Questionnaire Date: RPICC Facility: CMS use only Include the following

More information

Royal College of Physicians and Surgeons of Glasgow Travelling Fellowship Report

Royal College of Physicians and Surgeons of Glasgow Travelling Fellowship Report Royal College of Physicians and Surgeons of Glasgow Travelling Fellowship Report Mr Faisal Hanif MBBS, MD, FCPS, FRCSGlasg (Gen Surg) Department of HPB and Liver Transplant Surgery, Florence Nightingale

More information

ANNUAL REPORT ON KIDNEY TRANSPLANTATION

ANNUAL REPORT ON KIDNEY TRANSPLANTATION ANNUAL REPORT ON KIDNEY TRANSPLANTATION REPORT FOR 2013/2014 (1 APRIL 2004 31 MARCH 2014) PUBLISHED SEPTEMBER 2014 PRODUCED IN COLLABORATION WITH NHS ENGLAND Contents 1 Executive Summary... 1 2 Introduction...

More information

Many treatment and diagnostic options found in veterinary medicine today started

Many treatment and diagnostic options found in veterinary medicine today started New Treatment Options for Kidney Disease By William E. Feeman III, DVM Many treatment and diagnostic options found in veterinary medicine today started originally as treatment or diagnostic options for

More information

NHS BLOOD AND TRANSPLANT LIVER ADVISORY GROUP BLOOD GROUP: WAITING TIMES AND DEATHS ON THE TRANSPLANT LIST SUMMARY

NHS BLOOD AND TRANSPLANT LIVER ADVISORY GROUP BLOOD GROUP: WAITING TIMES AND DEATHS ON THE TRANSPLANT LIST SUMMARY BACKGROUND NHS BLOOD AND TRANSPLANT LIVER ADVISORY GROUP BLOOD GROUP: WAITING TIMES AND DEATHS ON THE TRANSPLANT LIST SUMMARY 1 Restrictions in the allocation of livers were imposed in 26 as a measure

More information

TRAVELLING FELLOWSHIP REPORT

TRAVELLING FELLOWSHIP REPORT ROYAL COLLEGE OF PHYSICIANS AND SURGEONS OF GLASGOW TRAVELLING FELLOWSHIP REPORT JANUARY 2014 Faisal Hanif MBBS, MD, FCPS, FRCSGlasg (Gen Surg) Department of HPB and Liver Transplantation Surgery Florence

More information

Expertise and Genuine Compassion Come Together

Expertise and Genuine Compassion Come Together Where World-Class Expertise Expertise and Genuine Compassion Come Together 0011000110100111100110111100000101010011000101100010111000010010000100010000100001011110101010101111000 000010111000101110011000110100111100110111100000101010011000101100010111000010010000100010000100

More information

Blood Transfusion. There are three types of blood cells: Red blood cells. White blood cells. Platelets.

Blood Transfusion. There are three types of blood cells: Red blood cells. White blood cells. Platelets. Blood Transfusion Introduction Blood transfusions can save lives. Every second, someone in the world needs a blood transfusion. Blood transfusions can replace the blood lost from a serious injury or surgery.

More information

using grafts from donation after circulatory death (DCD) and donation after brain death (DBD).

using grafts from donation after circulatory death (DCD) and donation after brain death (DBD). Research Original Investigation PACIFIC COAST SURGICAL ASSOCIATION Liver Transplantation in Children Using Organ Donation After Circulatory Death A Case-Control Outcomes Analysis of a 20-Year Experience

More information

June 2016. Introduction

June 2016. Introduction News from Scandiatransplant office June 2016 Introduction Main topics in this newsletter Updates in existing modules + Guidelines on infectious diseases + Information on urgent patients - Updates in existing

More information

DONATION AFTER CIRCULATORY DEATH A Basic Explanation for Donor Families

DONATION AFTER CIRCULATORY DEATH A Basic Explanation for Donor Families DONATION AFTER CIRCULATORY DEATH A Basic Explanation for Donor Families Donation after Circulatory Death (DCD), combined with compassionate end-of-life care, provides the best possible outcome by offering

More information

Organ and Tissue Donation: An Overview

Organ and Tissue Donation: An Overview Organ and Tissue Donation: An Overview E-learning module revised by LifeSource, 2012 This learning module is part of a series of e-learning modules designed to meet hospital education requirements for

More information

Robotic Partial Nephrectomy. Department of Urology Information for patients

Robotic Partial Nephrectomy. Department of Urology Information for patients Robotic Partial Nephrectomy Department of Urology Information for patients i Introduction You have recently been told that you need to have a tumour removed from your kidney. The standard operation to

More information

HCC: Risk factors, surveillance and the importance of a multidisciplinary team

HCC: Risk factors, surveillance and the importance of a multidisciplinary team HCC: Risk factors, surveillance and the importance of a multidisciplinary team Anjana Pillai MD Assistant Professor of Medicine Director, Emory University Hospital Liver Tumor Clinic Division of Digestive

More information

My Liver Transplant Journey:

My Liver Transplant Journey: My Liver Transplant Journey: Getting Started on My Pathway to Wellness 1 Liver Transplant Guide.indd 1 Multi-Organ Transplant Institute 1/26/16 11:18 AM I NEED A TRANSPLANT?!? WHAT EXACTLY DOES THIS MEAN?

More information

14.0 Stem Cell Laboratory Services

14.0 Stem Cell Laboratory Services Laboratory Services Contact Information: To inquire about assisting with surgical harvesting of bone marrow, cellular therapy (CT) product processing, cryopreservation, storage, or any other lab services,

More information

Bridging Techniques. What s between EMR and Traditional Surgery? Elisabeth C. McLemore, MD, FACS, FASCRS

Bridging Techniques. What s between EMR and Traditional Surgery? Elisabeth C. McLemore, MD, FACS, FASCRS Bridging Techniques What s between EMR and Traditional Surgery? Elisabeth C. McLemore, MD, FACS, FASCRS Associate Professor of Surgery Assistant Program Director, General Surgery Residency Disclosures

More information

FAQ. The Kidney Project

FAQ. The Kidney Project The Kidney Project FAQ Frequently asked questions sourced from and designed for patients living with end stage renal disease (ESRD) answered by Dr. Shuvo Roy and Dr. William Fissell. kidney.ucsf.edu kidneyproject@ucsf.edu

More information

Getting A New Heart Facts About Heart Transplants

Getting A New Heart Facts About Heart Transplants Release Date March 22, 2002 Revised December 2006 Revised March 2012 Getting A New Heart Facts About Heart Transplants American Society of Transplantation 1120 Route 73, Suite 200 Mount Laurel, NJ 08054

More information

Having a kidney transplant: Is it right for me? Information for patients Sheffield Kidney Institute (Renal Unit)

Having a kidney transplant: Is it right for me? Information for patients Sheffield Kidney Institute (Renal Unit) Having a kidney transplant: Is it right for me? Information for patients Sheffield Kidney Institute (Renal Unit) Introduction If you are thinking about having a kidney transplant, you will probably have

More information

Treatment options for Chronic Kidney Disease (CKD)

Treatment options for Chronic Kidney Disease (CKD) Treatment options for Chronic Kidney Disease (CKD) Hopefully you have found out about your chronic kidney disease at an early stage. If so, there are treatments to help protect your kidneys and prevent,

More information

Kidney/Pancreas Transplant Program

Kidney/Pancreas Transplant Program Recanati/Miller Transplantation Institute Kidney/Pancreas Transplant Program An RMTI transplant family: Gustav, heart transplant recipient 2005; daughter, Denise, kidney donor 2007; and wife, Gloria, kidney

More information

Organ and Tissue Procurement. Introduction

Organ and Tissue Procurement. Introduction Organ and Tissue Procurement Introduction The Lions of North Carolina are dedicated to the prevention of blindness and the restoration of sight. Since the 1950 s the Lions have been instrumental in educating

More information

Kidney Transplantation

Kidney Transplantation ilearning about your health Kidney Transplantation www.cpmc.org/learning What is Kidney Failure? Normally, kidneys filter waste products from your blood, control the balance of salt and water in your body,

More information

The effectiveness and cost-effectiveness of methods of storing donated kidneys from deceased donors: a systematic review and economic model

The effectiveness and cost-effectiveness of methods of storing donated kidneys from deceased donors: a systematic review and economic model The effectiveness and cost-effectiveness of storing donated kidneys from deceased donors The effectiveness and cost-effectiveness of methods of storing donated kidneys from deceased donors: a systematic

More information

What is Health Ethics?

What is Health Ethics? What is Health Ethics? By: Tory Fehrenbacher and Meredith Marston 1. 2. 3. Why is stem cell research ethical? Why is organ donation ethical? Health Ethics: A set of moral principles, beliefs and values

More information

Blood Transfusion Therapy in Trauma and Massive Hemorrhage Putting the Patient First

Blood Transfusion Therapy in Trauma and Massive Hemorrhage Putting the Patient First FACULTY OF MEDICINE, DENTISTRY AND HEALTH SCIENCES Blood Transfusion Therapy in Trauma and Massive Hemorrhage Putting the Patient First ALBERT FARRUGIA Historical Background Over last 40 years, transfusion

More information

Using Kidney Biomarkers for AKI: Risk Assessment, Diagnosis and Staging. Jay L. Koyner MD Section of Nephrology University of Chicago

Using Kidney Biomarkers for AKI: Risk Assessment, Diagnosis and Staging. Jay L. Koyner MD Section of Nephrology University of Chicago Using Kidney Biomarkers for AKI: Risk Assessment, Diagnosis and Staging Jay L. Koyner MD Section of Nephrology University of Chicago Disclosure Research funding from NIH/NIDDK /NHLBI Abbott / Abbvie Astute

More information

The State of the Liver in the Adult Patient after Fontan Palliation

The State of the Liver in the Adult Patient after Fontan Palliation The State of the Liver in the Adult Patient after Fontan Palliation Fred Wu, M.D. Boston Adult Congenital Heart Service Boston Children s Hospital/Brigham & Women s Hospital 7 th National Adult Congenital

More information

Transplantation: Living Kidney Donation. May 9, 2016 PKD Foundation

Transplantation: Living Kidney Donation. May 9, 2016 PKD Foundation Transplantation: Living Kidney Donation Seth Goldberg, MD May 9, 2016 PKD Foundation Conflicts of Interest Abbott Kadmon PKD Otsuka PKD Pfizer PKD Renal Replacement Therapies When kidneys fail, we now

More information