National Tall Man Lettering List
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1 National Tall Man Lettering List
2 Commonwealth of Australia 2011 The Australian Commission on Safety and Quality in Health Care encourages the not for profit reproduction of its documents and those of the former Council that are available on its web site, but requires acknowledgement of ownership. You may download, display, print and reproduce this material (retaining this notice, and any headers and footers) for your personal, non commercial use or use within your organisation. You may alter the contents of this material to suit the purposes of your organisation. All other rights are reserved. Print Online ISBN To be updated ISBN To be updated Australian Commission on Safety and Quality in Health Care. National Tall Man Lettering List, Australian Commission on Safety and Quality in Health Care, Sydney, Requests for authorisation should be directed to the: Australian Commission on Safety and Quality in Health Care GPO Box 5480 SYDNEY NSW 2001 Tel: Fax: If calling from overseas: Tel: Fax: National Tall Man Lettering List 2
3 Table of contents Section Title Page 1 Purpose 4 2 Reducing the risk of drug selection errors 4 3 Why develop a national Tall Man lettering standard? 5 4 Developing a national Tall Man lettering standard 5 Stage 1: Compilation of an Australian list of similar drug names 5 Stage 2: Prioritisation of drug name pairs for Tall Man application 6 Stage 3:Formulating the Tall Man names 7 Stage 4: User-testing the National Tall Man Lettering List 8 Stage 5: Maintaining the National Tall Man Lettering List 8 5 National Tall Man Lettering List 9 6 References 14 National Tall Man Lettering List 3
4 1. Purpose The National Tall Man Lettering List was developed for use in Australian health services to reduce the risk of drug selection error. Its application will allow incorporation of national standardised Tall Man lettering into: The National e-health Transition Authority s Australian Medicines Terminology; Other electronic health initiatives. It will also facilitate use of the technique more widely in Australia. The National Tall Man Lettering List is the first nationally standard application of Tall Man lettering. 2. Reducing the risk of drug selection errors It is reported that drug name confusion contributes to thousands of medication errors each year, 1 some causing significant patient harm. 2 Numerous lists of confusable drug names have been published in Australia and overseas. 3-6 These lists highlight the similarities between many pairs and groups of medicines currently marketed. Tall Man lettering is a typographic technique that uses selective capitalisation to help make similar looking drug names more easily differentiable. 7-9 The Australian Commission on Safety and Quality in Health Care (the Commission) supports the use of Tall Man lettering as part of a multi-faceted approach to reduce the risks associated with confusable drug names. Other interventions, such as the use of bar-code verification and thorough pre-market assessment processes also make valuable contributions to overall risk reduction and should be pursued by health care providers. National Tall Man Lettering List 4
5 3. Why develop a national Tall Man lettering standard? The objectives of developing a national standard for Tall Man lettering are to: Prevent the proliferation of various lists of Tall Man names, which may lead to inconsistency in the application of the technique and result in confusion amongst clinicians, software vendors, regulators and the pharmaceutical industry; Ensure that the best available scientific evidence is used to support the development of Tall Man names; and Provide credibility to the technique as a tool that can be used to help reduce the risks associated with look-alike, sound-alike drug names. It is envisaged that the standard will be incorporated into medical software in such a way as to enable the presentation of selected (high priority) drug names in Tall Man format in a variety of settings such as prescribing and dispensing software. It is intended to reduce the risk of drug name selection errors during prescribing or dispensing. In addition, pharmacies will be able to generate shelf labels with Tall Man lettering for use in pharmacies and hospital wards to reduce the risk of the wrong drug product being selected. 4. Developing a national Tall Man lettering standard The project to develop national Tall Man lettering proceeded in five stages during 2010 and Stage 1: Compilation of an Australian list of similar drug names This stage aimed to produce a comprehensive list of similar medicines names relevant to the Australian health care system. Names to be included in the Tall Man standard were subsequently selected from this list. In order to assemble a comprehensive list of similar medicines names, a variety of information sources was used. The work by Emmerton and Rizk 10 provided a good review of the literature related to similar drug names, and produced a list of pairs of drug names published in the international literature arising from cases of confusion. This list was supplemented from other information sources including international medication safety agencies, warnings and alerts, jurisdictional data bases and recent data from Pharmaceutical Defence Limited. National Tall Man Lettering List 5
6 The end result was a list of 250 pairs of confusable Australian drug names. The list comprised 341 discrete names, including 156 generic names and 185 trade names. Several names were similar to more than one other name, and several pharmacological classes of drug contain a number of agents with similar names. Stage 2: Prioritisation of drug name pairs for Tall Man application Research by Filik et al. 8 indicates that Tall Man lettering may be effective because drug names presented in this format appear novel and act as a warning. Overuse of the technique may, therefore, reduce its effectiveness as the names no longer appear novel. To ensure that Tall Man lettering has the greatest possible effect, its use should be reserved for those names associated with the highest risk to patient safety. These names must be identified through a formal risk assessment process. The aim of the risk assessment process was to reduce the compiled list of potentially confusable drug names relevant in the Australian health care environment to a succinct list of those names that are most likely to cause patient harm due to their confusability. Pairs/groups of drug names were identified by a risk matrix based on: The likelihood that the names would be confused, and The potential severity (consequence) of this confusion. Rigorous methodologies were developed to calculate both likelihood of confusion and potential severity. Both methodologies are explained in the detail in the Tall Man Lettering Final Report available on the Commission web site at These risk assessment processes were compiled to ensure that the actions taken by the Commission to derive the national standard for Tall Man lettering were transparent, reproducible and based on the best available evidence. National Tall Man Lettering List 6
7 Stage 3: Formulating Tall Man names In this stage, the Tall Man format was derived for the highest priority drug pair names identified in Stage 2. Various permutations of Tall Man typography have been represented in the literature. The common element is the attempt to highlight the differences between the two names. Van de Vreede et al. 11 outlined the following as a set of principles for their application of Tall Man typography: Highlight three to five letters that are different; Choose, if possible, letters that form a syllable; and Highlight letters closest to the beginning of the word that are different, to facilitate correct selection when electronic drop-down menus are used. Evidence suggested mid-tall Man lettering as the most appropriate permutation and it was selected. 12 Step one Working from the first letter of the medicine name take each common character to the right until two or more characters are different, and from that point on capitalise the characters. Thus: cefuroxime cefotaxime ceftazidime Become: cefuroxime cefotaxime ceftazidime Step two Working from the last letter of the word, take each capitalised common character to the left until two or more characters are different, and change the capital letters to that point back to lowercase. Thus: cefuroxime cefotaxime ceftazidime Become: cefuroxime cefotaxime ceftazidime Some exceptions to the mid-tall Man lettering method were required for particular instances, such as large groups of confusable names, such as the cephalosporins. National Tall Man Lettering List 7
8 Stage 4: User-testing the National Tall Man Lettering List Ensuring the proposed National Tall Man Lettering List was not detrimental was critical to its acceptance. The list was human factors tested using approximately 65 clinicians to record responses to the medicines names with Tall Man lettering applied. Testing covered the rates of selection error using three formats; natural case, mid-tall Man and random capitalisation. Outcomes included that random capitalisation performed more poorly than mid-tall Man and natural case, and that there was a trend to less selection errors with mid-tall Man lettering. The conclusion drawn was that standardised Tall Man is not detrimental. Detailed results are available in the National Tall Man Lettering Human Factors Testing Report available on the Commission web site at Stage 5: Maintaining the National Tall Man Lettering List To ensure that the standard maintains currency, it is important that the Commission both reactively and proactively assesses the standard. As with all Commission-managed national standardisations, an issues register will be established to enable clinicians (and potentially members of the public) to notify the Commission of drug name pairs, or groups, that they believe pose a risk to patient safety and that may benefit from the application of Tall Man lettering. The notifications can be tested using the methodologies identified in Stage 2 above. The Commission will encourage rigorous assessment through the use of pre-market testing (including software) to highlight similar medicine names. National Tall Man Lettering List 8
9 5. National Tall Man Lettering List actonel akamin aldomet alphapress amaryl amiodarone amlodipine amitriptyline apomine aratac atropt azathioprine ERYthromycin bisoprolol bumetanide carafate CARBAMazepine carvedilol celapram cipramil clarithromycin clomipramine coumadin cyclosporin DEPO-medrol DEPO-medrol solu-cortef* actos aclin aldactone alodorm alphapril amoxil amlodipine amitriptyline aminophylline avomine aropax arabloc azopt azithromycin bisacodyl budesonide caltrate OXCARBazepine carbimazole* captopril celebrex ciproxin ciprofloxacin clomiphene chlorpromazine coversyl cycloserine SOLU-medrol depo-provera* SOLU-medrol National Tall Man Lettering List 9
10 deptran dilaudid diprivan dipyridamole dothiepin deralin dilantin ditropan disopyramide doxepin humalog hydrea hydralazine isopto HOMATROpine ISOtretinoin janumet ketalar lamictal lamivudine lantus lipidil losec methadone meruvax metohexal MOXIfloxacin mobilis morphine* NEOral neurontin nexavar nimodipine norvasc novomix humulin hydrene hydrochlorothiazide isopto CARpine tretinoin januvia ketorolac largactil lamisil lamotrigine lanvis lipazil lovan methylphenidate merieux mellihexal NORfloxacin movalis HYDROmorphone* INDEral noroxin nexium nifedipine nizatidine normison novorapid National Tall Man Lettering List 10
11 oxycontin paxtine pexsig primaxin prograf promethazine propranolol QUETIAPine risperidone sitagliptin SIrolimus sulfasalazine topamax tegretol tramadol trimeprazine imipramine* valaciclovir xalatan zinvit zocor zoloft MS Contin* oxynorm pariet pristiq primacor primacin* prozac prochlorperazine propofol SERTRALine ropinirole sumatriptan TACrolimus sulfadiazine tofranil trental temodal* toradol trimethoprim trimipramine trimipramine valganciclovir xalacom zinnat zoton zocor National Tall Man Lettering List 11
12 Agents used predominantly in cancer therapy cisplatin carboplatin cyclizine cycloblastin dactinomycin daptomycin DAUNOrubicin DOXOrubicin IDArubicin DOCEtaxel PACLItaxel IFOSFamide CYCLOPHOSPHamide INFLIximab RITUximab taxol taxotere vinblastine vincristine vinorelbine avastin avaxim ALKeran LEUKeran MYLeran National Tall Man Lettering List 12
13 Group names Cephalosporins cefepime cefotaxime cefoxitin ceftazidime ceftriaxone cefalotin cephalexin cephazolin Benzodiazepines CLONazepam DIazepam OXazepam LORazepam SSRI / SNRI fluoxetine DULoxetine PARoxetine fluvoxamine Sulphonylurea Agents glibenclamide gliclazide glimepiride glipizide National Tall Man Lettering List 13
14 6. References 1. Phatak HM, Cady PS, Heyneman CA, Culbertson VL. Retrospective Detection of Potential Medication Errors Involving Drugs with Similar Names. Journal of the American Pharmacists Association. 2005;45: Hoffman JM, Proulx SM. Medication Errors Caused by Confusion of Drug Names. Drug Safety. 2003;26(7): Pharmaceutical Defence Limited. Ninety Sixth Annual Report and Statement of Accounts for the year ended 30 June Hawthorn, Victoria; Davis NM, Cohen MR, Teplitsky B. Look alike and sound alike drug names: the problem and the solution. Hospital Pharmacy. 1992;27(2):95 8, 102 5, Practices IfSM. ISMP's List of Confused Drug Names [cited October, 2010]; Available from: 6. United States Pharmacopeia. Use Caution Avoid Confusion. USP Quality Review; FIlik R, Purdy K, Gale A, Gerrett D. Drug name confusion: evaluating the effectiveness of capital ("Tall Man") letters using eye movement data. Social Science and Medicine. 2004;59: FIlik R, Purdy K, Gale A, Gerrett D. Labeling of Medicines and Patient Safety: Evaluating Methods of Reducing Drug Name Confusion. Human Factors. 2006;48(1): Gabriele S. The Role of Typography in Differentiating Look Alike/Sound Alike Drug Names. Healthcare Quarterly. 2006;9(Special Issue): Emmerton L, Rizk M. Look Alike and Sound Alike Medicines: Reducing the Risk of Errors: The University of Queensland; Van de Vreede M, McRae A, Wiseman M, Dooley M. Successful Introduction of Tallman Letters to Reduce Medication Selection Errors in a Hospital Network. Journal of Pharmacy Practice and Research. 2008;38(4): Gerrett D, Gale A, Darker IT, FIlik R, Purdy KJ. Final Report of The Use of Tall Man Lettering to Minimise Selection Errors of Medicine Names in Computer Prescribing and Dispensing Systems: NHS Connecting for Health National Tall Man Lettering List 14
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More informationPermanent Link: http://espace.library.curtin.edu.au/r?func=dbin-jump-full&local_base=gen01-era02&object_id=171379
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