Cancer in Primary Care: Prostate Cancer Screening. How and How often? Should we and in which patients?

Size: px
Start display at page:

Download "Cancer in Primary Care: Prostate Cancer Screening. How and How often? Should we and in which patients?"

Transcription

1 Cancer in Primary Care: Prostate Cancer Screening How and How often? Should we and in which patients?

2

3

4

5

6 PLCO trial (Prostate, Lung, Colorectal and Ovarian) Results In the screening group, rates of compliance were 85% for PSA testing and 86% for digital rectal examination. Rates of screening in the control group increased from 40% in the first year to 52% in the sixth year for PSA testing. After 7 years of follow-up, the incidence of death per 10,000 person-years was 2.0 (50 deaths) in the screening group and 1.7 (44 deaths) in the control group. The data at 10 years were 67% complete and consistent with these overall findings.

7 ERSPC European Randomized Study of Screening for Prostate Cancer Largest randomized trial with 182,000 men from seven European countries At 11 years: 214 prostate ca deaths in the screening group 326 prostate cancer deaths in the control group (with 20% contamination in the control group) 20% decrease in prostate cancer deaths 29% decrease if adjusted for overall screening 1 death from prostate ca prevented per 1000 randomized patients

8 The USPSTF recommends against prostate-specific antigen (PSA) based screening for prostate cancer (grade D recommendation). A grade D recommendation means that the USPSTF has concluded that there is at least moderate certainty that the harms of doing the intervention equal or outweigh the benefits in the target population, whereas a grade C recommendation means that the USPSTF has concluded that there is at least moderate certainty that the overall net benefit of the service is small.

9 Screening for Prostate Cancer: USPSTF Recommendations Statement The U.S. PLCO and ERSPC Trials were primarily used because they had the largest populations and were of the highest quality The U.S. trial did not demonstrate any reduction of prostate cancer mortality. The European trial found a reduction in prostate cancer deaths of approximately 1 death per 1000 men screened in a subgroup aged 55 to 69 years

10 Screening for Prostate Cancer: USPSTF Recommendations Statement Mortality from prostate cancer peaked between 1991 and roughly the same time when PSA Screening became available, and began to decline after that Although this positive trend may be related to increased screening, other factors, including new treatment approaches, could also account for some or all of the observed decline in mortality

11 Screening for Prostate Cancer: USPSTF Recommendations Statement Comment on PIVOT Trial: Randomized 731 men ages 75 or younger, PSA levels less than 50, and clinically localized prostate cancer to: radical prostatectomy versus watchful waiting Treated patients with a PSA greater than 10 had an absolute risk reduction of prostate-specific and all-cause mortality of 7.2% and 13.2% respectively.

12 Guideline Statement 1: The Panel recommends against PSA screening in men under age 40 years. Guideline Statement 2: The Panel does not recommend routine screening in men between ages 40 to 54 years at average risk. For men younger than age 55 years at higher risk (e.g. positive family history or African American race), decisions regarding prostate cancer screening should be individualized.

13 Guideline Statement 3: For men ages 55 to 69 years the Panel recognizes that the decision to undergo PSA screening involves weighing the benefits of preventing prostate cancer mortality in 1 man for every 1,000 men screened over a decade against the known potential harms associated with screening and treatment. For this reason, the Panel strongly recommends shared decision-making for men age 55 to 69 years that are considering PSA screening, and proceeding based on a man's values and preferences.

14 Guideline Statement 4: To reduce the harms of screening, a routine screening interval of two years or more may be preferred over annual screening in those men who have participated in shared decision-making and decided on screening. Guideline Statement 5: The Panel does not recommend routine PSA screening in men age 70+ years or any man with less than a 10 to 15 year life expectancy. Some men age 70+ years who are in excellent health may benefit from prostate cancer screening.

15 Some men with high risk aggressive prostate cancer with a life expectancy of less than a decade may benefit from the diagnosis and treatment of their disease, such as patients with a PSA of at least 10 ng/ml. Thus, the goal should be to identify these men while avoiding associated overdiagnosis and overtreatment

16 Natl Cancer Inst Aug 20;100(16): Radical prostatectomy versus watchful waiting in localized prostate cancer: the Scandinavian prostate cancer group-4 randomized trial. METHODS: From October 1, 1989, through February 28, 1999, 695 men with clinically localized prostate cancer were randomly assigned to radical prostatectomy (n = 347) or watchful waiting (n = 348). RESULTS: At 12 years, 12.5% of the surgery group and 17.9% of the watchful waiting group had died of prostate cancer At 12 years, 19.3% of men in the surgery group and 26% of men in the watchful waiting group had been diagnosed with distant metastases (difference = 6.7% ; P =.006).

17

18

4/8/13. Pre-test Audience Response. Prostate Cancer 2012. Screening and Treatment of Prostate Cancer: The 2013 Perspective

4/8/13. Pre-test Audience Response. Prostate Cancer 2012. Screening and Treatment of Prostate Cancer: The 2013 Perspective Pre-test Audience Response Screening and Treatment of Prostate Cancer: The 2013 Perspective 1. I do not offer routine PSA screening, and the USPSTF D recommendation will not change my practice. 2. In light

More information

Screening for Prostate Cancer: Understanding the Evidence, Differences in Screening Guidelines, and Future Directions

Screening for Prostate Cancer: Understanding the Evidence, Differences in Screening Guidelines, and Future Directions Screening for Prostate Cancer: Understanding the Evidence, Differences in Screening Guidelines, and Future Directions American Council of Life Insurers Medical Section Annual Meeting February 24, 2013

More information

PSA Screening and the USPSTF Understanding the Controversy

PSA Screening and the USPSTF Understanding the Controversy PSA Screening and the USPSTF Understanding the Controversy Peter C. Albertsen Division of Urology University of Connecticut Farmington, CT, USA USPSTF Final Report 1 Four Key Questions 1. Does PSA based

More information

Prostate Cancer Screening: Are We There Yet? March 2010 Andrew M.D. Wolf, MD University of Virginia School of Medicine

Prostate Cancer Screening: Are We There Yet? March 2010 Andrew M.D. Wolf, MD University of Virginia School of Medicine Prostate Cancer Screening: Are We There Yet? March 2010 Andrew M.D. Wolf, MD University of Virginia School of Medicine Case #1 A 55 yo white man with well-controlled hypertension presents for his annual

More information

The use of PSA testing in general practice. Ross Lawrenson Waikato Clinical Campus University of Auckland

The use of PSA testing in general practice. Ross Lawrenson Waikato Clinical Campus University of Auckland The use of PSA testing in general practice Ross Lawrenson Waikato Clinical Campus University of Auckland The Team Prostate cancer American Joint Committee on Cancer (AJCC) Staging System The AJCC staging

More information

Prostate-Specific Antigen (PSA) Based Population Screening for Prostate Cancer: OHTAC Recommendation

Prostate-Specific Antigen (PSA) Based Population Screening for Prostate Cancer: OHTAC Recommendation Prostate-Specific Antigen (PSA) Based Population Screening for Prostate Cancer: OHTAC Recommendation HEALTH QUALITY ONTARIO ONTARIO HEALTH TECHNOLOGY ADVISORY COMMITTEE RECOMMENDATION OHTAC recommends

More information

PSA: Screening for Prostate Cancer in Older Adults

PSA: Screening for Prostate Cancer in Older Adults PSA: Screening for Prostate Cancer in Older Adults William Dale, MD, PhD University of Chicago Sections of Geriatrics & Palliative Medicine and Hematology/Oncology Director, Specialized Oncology Care &

More information

Prostate Cancer Screening Recommendations from the US Preventive Services Task Force: Evidence and implementation to optimize health outcomes

Prostate Cancer Screening Recommendations from the US Preventive Services Task Force: Evidence and implementation to optimize health outcomes Prostate Cancer Screening Recommendations from the US Preventive Services Task Force: Evidence and implementation to optimize health outcomes Timothy J. Wilt, MD, MPH, MACP University of Minnesota and

More information

Prostate Cancer Screening

Prostate Cancer Screening Prostate Cancer Screening Bruce L. Houghton, MD Associate Professor of Medicine Division of General Medicine Department of Internal Medicine Creighton University School of Medicine http://en.wikipedia.org/wiki/image:prostatelead.jpg

More information

Controversites: Screening for Prostate Cancer in Older Adults

Controversites: Screening for Prostate Cancer in Older Adults Controversites: Screening for Prostate Cancer in Older Adults William Dale, MD, PhD University of Chicago Sections of Geriatrics & Palliative Medicine and Hematology/Oncology Director, Specialized Oncology

More information

Breast cancer screening and prevention: Update from the USPSTF

Breast cancer screening and prevention: Update from the USPSTF Breast cancer screening and prevention: Update from the USPSTF Mark H. Ebell MD, MS Member, USPSTF College of Public Health The University of Georgia What we re going to do today Overview of the USPSTF

More information

Clinical Practice Guidelines

Clinical Practice Guidelines Clinical Practice Guidelines Prostate Cancer Screening CareMore Quality Management CareMore Health System adopts Clinical Practice Guidelines for the purpose of improving health care and reducing unnecessary

More information

Cancer research in the Midland Region the prostate and bowel cancer projects

Cancer research in the Midland Region the prostate and bowel cancer projects Cancer research in the Midland Region the prostate and bowel cancer projects Ross Lawrenson Waikato Clinical School University of Auckland MoH/HRC Cancer Research agenda Lung cancer Palliative care Prostate

More information

PSA Testing for Prostate Cancer An information sheet for men considering a PSA Test

PSA Testing for Prostate Cancer An information sheet for men considering a PSA Test PSA Testing for Prostate Cancer An information sheet for men considering a PSA Test What is the aim of this leaflet? Prostate cancer is a serious condition. The PSA test, which can give an early indication

More information

Prostate Cancer Screening: What We ve Learned and Where we should go

Prostate Cancer Screening: What We ve Learned and Where we should go Prostate Cancer Screening: What We ve Learned and Where we should go Gerald L. Andriole, MD Robert K. Royce Distinguished Professor Chief of Urologic Surgery Siteman Cancer Center Washington University

More information

Modeling Drivers of Cost and Benefit for Policy Development in Cancer

Modeling Drivers of Cost and Benefit for Policy Development in Cancer Modeling Drivers of Cost and Benefit for Policy Development in Cancer Harms? Benefits? Costs? Ruth Etzioni Fred Hutchinson Cancer Research Center Seattle, Washington The USPSTF recommends against routine

More information

PSA Screening for Prostate Cancer Information for Care Providers

PSA Screening for Prostate Cancer Information for Care Providers All men should know they are having a PSA test and be informed of the implications prior to testing. This booklet was created to help primary care providers offer men information about the risks and benefits

More information

1. What is the prostate-specific antigen (PSA) test?

1. What is the prostate-specific antigen (PSA) test? 1. What is the prostate-specific antigen (PSA) test? Prostate-specific antigen (PSA) is a protein produced by the cells of the prostate gland. The PSA test measures the level of PSA in the blood. The doctor

More information

The Prostate-Specific Antigen (PSA) Test: Questions and Answers

The Prostate-Specific Antigen (PSA) Test: Questions and Answers The Prostate-Specific Antigen (PSA) Test: Questions and Answers Key Points Prostate-specific antigen (PSA) is a protein produced by the cells of the prostate gland. The PSA test measures the level of PSA

More information

Prostate cancer screening- pro and contra, lessons from the ERSPC study

Prostate cancer screening- pro and contra, lessons from the ERSPC study Prostate cancer screening- pro and contra, lessons from the ERSPC study Are we ready for a population-based screening program? Dr. Pim J.van Leeuwen Erasmus MC, Rotterdam, The Netherlands On behalf of

More information

Update on Prostate Cancer Current Controversies Lucas Jacomides, M.D.

Update on Prostate Cancer Current Controversies Lucas Jacomides, M.D. Update on Prostate Cancer Current Controversies Lucas Jacomides, M.D. Assistant Professor of Surgery, Texas A&M Health Science Center College of Medicine Director of Urology, Scott & White-Round Rock The

More information

Clinical Practice Guidelines and Shared Decision Making for Prostate Cancer Screening

Clinical Practice Guidelines and Shared Decision Making for Prostate Cancer Screening Clinical Practice Guidelines and Shared Decision Making for Prostate Cancer Screening Dr. Roger Luckmann Associate Professor Family Medicine and Community Health UMass Medical School Disclosures I have

More information

Prostate cancer. Christopher Eden. The Royal Surrey County Hospital, Guildford & The Hampshire Clinic, Old Basing.

Prostate cancer. Christopher Eden. The Royal Surrey County Hospital, Guildford & The Hampshire Clinic, Old Basing. Prostate cancer Christopher Eden The Royal Surrey County Hospital, Guildford & The Hampshire Clinic, Old Basing. Screening Screening men for PCa (prostate cancer) using PSA (Prostate Specific Antigen blood

More information

Prostate cancer screening. It s YOUR decision!

Prostate cancer screening. It s YOUR decision! Prostate cancer screening It s YOUR decision! For many years now, a test has been available to screen for. The test is called the prostate-specific antigen blood test (or PSA test). It is used in combination

More information

TO SCREEN OR NOT TO SCREEN: THE PROSTATE CANCER

TO SCREEN OR NOT TO SCREEN: THE PROSTATE CANCER TO SCREEN OR NOT TO SCREEN: THE PROSTATE CANCER DILEMMA Thomas J Stormont MD January 2012 http://www.youtube.com/watch?v=8jd 7bAHVp0A&feature=related related INTRODUCTION A government health panel (the

More information

Conflict of Interest Disclosures. Outcome of interest. USPSTF Grades. Deepu Gowda, MD, MPH. Screening for the following cancers:

Conflict of Interest Disclosures. Outcome of interest. USPSTF Grades. Deepu Gowda, MD, MPH. Screening for the following cancers: Cancer Screening: Cervical, Colon, Breast, and Prostate Screening Update Conflict of Interest Disclosures Deepu Gowda, MD, MPH Assistant Professor of Clinical Medicine Intensive Review of Internal Medicine

More information

Prostate Cancer Screening Clinical Practice Guideline. Approved by the National Guideline Directors November, 2013

Prostate Cancer Screening Clinical Practice Guideline. Approved by the National Guideline Directors November, 2013 Prostate Cancer Screening Clinical Practice Guideline This guideline is informational only. It is not intended or designed as a substitute for the reasonable exercise of independent clinical judgment by

More information

Oncology Annual Report: Prostate Cancer 2005 Update By: John Konefal, MD, Radiation Oncology

Oncology Annual Report: Prostate Cancer 2005 Update By: John Konefal, MD, Radiation Oncology Oncology Annual Report: Prostate Cancer 25 Update By: John Konefal, MD, Radiation Oncology Prostate cancer is the most common cancer in men, with 232,9 new cases projected to be diagnosed in the U.S. in

More information

Early Prostate Cancer: Questions and Answers. Key Points

Early Prostate Cancer: Questions and Answers. Key Points CANCER FACTS N a t i o n a l C a n c e r I n s t i t u t e N a t i o n a l I n s t i t u t e s o f H e a l t h D e p a r t m e n t o f H e a l t h a n d H u m a n S e r v i c e s Early Prostate Cancer:

More information

PSA Testing 101. Stanley H. Weiss, MD. Professor, UMDNJ-New Jersey Medical School. Director & PI, Essex County Cancer Coalition. weiss@umdnj.

PSA Testing 101. Stanley H. Weiss, MD. Professor, UMDNJ-New Jersey Medical School. Director & PI, Essex County Cancer Coalition. weiss@umdnj. PSA Testing 101 Stanley H. Weiss, MD Professor, UMDNJ-New Jersey Medical School Director & PI, Essex County Cancer Coalition weiss@umdnj.edu September 23, 2010 Screening: 3 tests for PCa A good screening

More information

The 4Kscore blood test for risk of aggressive prostate cancer

The 4Kscore blood test for risk of aggressive prostate cancer The 4Kscore blood test for risk of aggressive prostate cancer Early detection of aggressive prostate cancer Challenges Serum PSA has a high false positive rate Over 1 million prostate biopsies performed

More information

PSA screening in asymptomatic men the debate continues www.bpac.org.nz keyword: psa

PSA screening in asymptomatic men the debate continues www.bpac.org.nz keyword: psa PSA screening in asymptomatic men the debate continues www.bpac.org.nz keyword: psa Key messages: PSA is present in the benign and malignant prostate There is currently no national screening programme

More information

Prostate-Specific Antigen Based Screening: Controversy and Guidelines

Prostate-Specific Antigen Based Screening: Controversy and Guidelines Prostate-Specific Antigen Based Screening: Controversy and Guidelines Eric H. Kim and Gerald L. Andriole Institutional Address: Washington University School of Medicine 4960 Children's Place Campus Box

More information

The PLCO Trial Not a comparison of Screening vs no Screening

The PLCO Trial Not a comparison of Screening vs no Screening PSA Screening: Science, Politics and Uncertainty David F. Penson, MD, MPH Hamilton and Howd Chair of Urologic Oncology Professor and Chair, Department of Urologic Surgery Director, Center for Surgical

More information

Prostate Cancer: Screening Update Middlesex Hospital Cancer Center Comprehensive Prostate Cancer Program

Prostate Cancer: Screening Update Middlesex Hospital Cancer Center Comprehensive Prostate Cancer Program Prostate Cancer: Screening Update Middlesex Hospital Cancer Center Comprehensive Prostate Cancer Program Edward G. Myer, M.D. Middlesex Urology, P.C. October 15, 2015 Middlesex Hospital Cancer Center Comprehensive

More information

Update on Prostate Cancer Screening Guidelines

Update on Prostate Cancer Screening Guidelines www.medscape.com Update on Prostate Cancer Screening Guidelines Christine Gonzalez, PharmD, CHHC US Pharmacist Abstract and Introduction Introduction In the United States, prostate cancer is the most common

More information

DECISION AID TOOL PROSTATE CANCER SCREENING WITH PSA TESTING

DECISION AID TOOL PROSTATE CANCER SCREENING WITH PSA TESTING DECISION AID TOOL PROSTATE CANCER SCREENING WITH PSA TESTING This booklet is what is often called a decision aid. The goals of a decision aid are to help people better understand their medical choices

More information

Early Detection of Prostate Cancer: Sunnybrook Health Sciences Centre Professor of Surgery University of Toronto

Early Detection of Prostate Cancer: Sunnybrook Health Sciences Centre Professor of Surgery University of Toronto Early Detection of Prostate Cancer: How to do it smart Laurence Klotz Sunnybrook Health Sciences Centre Professor of Surgery University of Toronto If screening was a pill: You are a 60 year old male and

More information

PSA screening: Controversies and Guidelines

PSA screening: Controversies and Guidelines PSA screening: Controversies and Guidelines John Phillips, MD, FACS Department of Urology Urology Center of Westchester New York Medical College Historical PerspecGve Cancer of the prostate, although rare,

More information

Prostate Cancer Screening Guideline

Prostate Cancer Screening Guideline Prostate Cancer Screening Guideline Contents Prevention 2 Screening Recommendations 2 Shared Decision Making 2 Test Recommendations 3 Follow-up/Referral 3 Treatment Overview 4 Evidence Summary 4 References

More information

Prostate Cancer Screening Report and Recommendations

Prostate Cancer Screening Report and Recommendations Working together to improve health care quality, outcomes, and affordability in Washington State. Prostate Cancer Screening Report and Recommendations September 2015 Table of Contents Executive Summary...

More information

Making sense of prostate cancer screening

Making sense of prostate cancer screening Making sense of prostate cancer screening Piotr Czaykowski MD MSc FRCPC Medical Oncology, CancerCare Manitoba University of Manitoba Disclosure of Potential for Conflict of Interest Name of presenter Name

More information

Prostate Cancer Early Detection: Update 2010

Prostate Cancer Early Detection: Update 2010 Prostate Cancer Early Detection: Update 2010 Prostate Cancer. Disease Burden The most common non-skin cancer, and the second leading cause of cancer death among U.S. men It is estimated that: 1 in 6 men

More information

Questions to ask my doctor: About prostate cancer

Questions to ask my doctor: About prostate cancer Questions to ask my doctor: About prostate cancer Being diagnosed with prostate cancer can be scary and stressful. You probably have a lot of questions and concerns. Learning about the disease, how it

More information

The 4Kscore blood test for risk of aggressive prostate cancer

The 4Kscore blood test for risk of aggressive prostate cancer The 4Kscore blood test for risk of aggressive prostate cancer Prostate cancer tests When to use the 4Kscore Test? Screening Prior to 1 st biopsy Prior to negative previous biopsy Prognosis in Gleason 6

More information

U.S. Preventive Services Task Force

U.S. Preventive Services Task Force U.S. Preventive Services Task Force Screening for Prostate Cancer: Recommendation Statement See related Putting Prevention into Practice on page 283. This summary is one in a series excerpted from the

More information

Testing for Prostate Cancer. Should I be tested? Is it the right choice for me?

Testing for Prostate Cancer. Should I be tested? Is it the right choice for me? Testing for Prostate Cancer Should I be tested? Is it the right choice for me? Prostate cancer affects many men. There are tests to find it early. There may be benefits and risks with testing. Research

More information

Prostate Cancer Screening in Taiwan: a must

Prostate Cancer Screening in Taiwan: a must Prostate Cancer Screening in Taiwan: a must 吳 俊 德 基 隆 長 庚 醫 院 台 灣 醫 學 會 105 th What is the PSA test? The blood level of PSA is often elevated in men with prostate cancer, and the PSA test was originally

More information

Guidelines for Cancer Prevention, Early detection & Screening. Prostate Cancer

Guidelines for Cancer Prevention, Early detection & Screening. Prostate Cancer Guidelines for Cancer Prevention, Early detection & Screening Prostate Cancer Intervention Comments & Recommendations For primary prevention, it has been suggested that diets low in meat & other fatty

More information

Prostate cancer trends in Canada, 1995 to 2012

Prostate cancer trends in Canada, 1995 to 2012 Catalogue no.82-624 X ISSN 1925-6493 Health at a Glance by Lawrence Ellison Release date: April 25, 2016 How to obtain more information For information about this product or the wide range of services

More information

The Centers for Medicare & Medicaid Services (CMS) seeks stakeholder comments on the following clinical quality measure under development:

The Centers for Medicare & Medicaid Services (CMS) seeks stakeholder comments on the following clinical quality measure under development: The Centers for Medicare & Medicaid Services (CMS) seeks stakeholder comments on the following clinical quality measure under development: Title: Non-Recommended PSA-Based Screening Description: The percentage

More information

Screening for Cancer in Light of New Guidelines and Controversies. Christopher Celio, MD St. Jude Heritage Medical Group

Screening for Cancer in Light of New Guidelines and Controversies. Christopher Celio, MD St. Jude Heritage Medical Group Screening for Cancer in Light of New Guidelines and Controversies Christopher Celio, MD St. Jude Heritage Medical Group Screening Tests The 2 major objectives of a good screening program are: (1) detection

More information

American Urological Association (AUA) Guideline

American Urological Association (AUA) Guideline 1 (AUA) Guideline EARLY DETECTION OF PROSTATE CANCER: AUA GUIDELINE Approved by the AUA Board of Directors April 2013 Authors disclosure of potential conflicts of interest and author/staff contributions

More information

Prostate Cancer. Screening and Diagnosis. Screening. Pardeep Kumar Consultant Urological Surgeon

Prostate Cancer. Screening and Diagnosis. Screening. Pardeep Kumar Consultant Urological Surgeon The Royal Marsden Prostate Cancer Screening and Diagnosis Pardeep Kumar Consultant Urological Surgeon Prostate Cancer Screening and Diagnosis 08 02 2013 2 Screening 1 3 Q1.Lots of men have prostate cancer

More information

Summary of Harms from Screening and Treatment for Prostate Cancer

Summary of Harms from Screening and Treatment for Prostate Cancer DRAFT: Advice from Dr John Childs MoH advisor Summary of Harms from Screening and Treatment for Prostate Cancer There are minimal risks directly attributable to PSA testing or transrectal ultrasound (TRUS)

More information

November 25, 2015. Albert L Siu, MD, MSPH Chair, US Preventive Services Task Force 5600 Fishers Lane, Mail Stop 06E53A Rockville, MD 20857

November 25, 2015. Albert L Siu, MD, MSPH Chair, US Preventive Services Task Force 5600 Fishers Lane, Mail Stop 06E53A Rockville, MD 20857 November 25, 2015 Men's Health Network P. O. Box 75972 Washington, D.C. 20013 202-543-MHN-1 (6461) Fax 202-543-2727 Albert L Siu, MD, MSPH Chair, US Preventive Services Task Force 5600 Fishers Lane, Mail

More information

Screening for Prostate Cancer

Screening for Prostate Cancer Screening for Prostate Cancer It is now clear that screening for Prostate Cancer discovers the disease at an earlier and more curable stage. It is not yet clear whether this translates into reduced mortality

More information

Re: USPSTF Proposed Recommendation Statement on Screening for Prostate Cancer

Re: USPSTF Proposed Recommendation Statement on Screening for Prostate Cancer Men's Health Network P. O. Box 75972 Washington, D.C. 20013 202-543-MHN-1 (6461) Fax 202-543-2727 November 8, 2011 Dr. Robert Cosby c/o USPSTF 540 Gaither Road Rockville, MD 20850 Re: USPSTF Proposed Recommendation

More information

2010 SITE REPORT St. Joseph Hospital PROSTATE CANCER

2010 SITE REPORT St. Joseph Hospital PROSTATE CANCER 2010 SITE REPORT St. Joseph Hospital PROSTATE CANCER Humboldt County is located on the Redwood Coast of Northern California. U.S census data for 2010 reports county population at 134,623, an increase of

More information

Screening for Prostate Cancer

Screening for Prostate Cancer Screening for Prostate Cancer Review against programme appraisal criteria for the UK National Screening Committee (UK NSC) Version 1: This document summarises the work of ScHARR 1 2 and places it against

More information

NCCN Prostate Cancer Early Detection Guideline

NCCN Prostate Cancer Early Detection Guideline NCCN Prostate Cancer Early Detection Guideline Joan McClure Senior Vice President National Comprehensive Cancer Network African American Prostate Cancer Disparity Summit September 22, 2006 Washington,

More information

7. Prostate cancer in PSA relapse

7. Prostate cancer in PSA relapse 7. Prostate cancer in PSA relapse A patient with prostate cancer in PSA relapse is one who, having received a primary treatment with intent to cure, has a raised PSA (prostate-specific antigen) level defined

More information

Prostate Cancer Screening

Prostate Cancer Screening Prostate Cancer Screening The American Cancer Society and Congregational Health Ministry Team June Module To access this module via the Web, visit www.cancer.org and type in congregational health ministry

More information

Testing for Prostate Cancer

Testing for Prostate Cancer Testing for Prostate Cancer Should I be tested? Is it the right choice for me? Prostate cancer affects many men. There are tests to find it early. There may be benefits and risks with testing. Research

More information

Cigna Medical Coverage Policy

Cigna Medical Coverage Policy Cigna Medical Coverage Policy Subject Prostate-Specific Antigen (PSA) Screening for Prostate Cancer Table of Contents Coverage Policy... 1 General Background... 2 Coding/Billing Information... 14 References...

More information

The PSA Test for Prostate Cancer Screening:

The PSA Test for Prostate Cancer Screening: For more information, please contact your local VA Medical Center or Health Clinic. U.S. Department of Veterans Affairs Veterans Health Administration Patient Care Services Health Promotion and Disease

More information

Vitamin Supplementation amongst Otherwise Healthy Individuals

Vitamin Supplementation amongst Otherwise Healthy Individuals 01.13.14 SOURCE: HTTP://WWW.ONEILLINSTITUTEBLOG.ORG/FOUR-THINGS- PROBABLY-STOP-NAME-PUBLIC-HEALTH-2014/# FOUR THINGS WE SHOULD PROBABLY STOP DOING IN THE NAME OF PUBLIC HEALTH IN 2014 BY BRIAN J. HONERMANN

More information

Establishing a Cohort of African-American Men to Validate a Method for using Serial PSA Measures to Detect Aggressive Prostate Cancers

Establishing a Cohort of African-American Men to Validate a Method for using Serial PSA Measures to Detect Aggressive Prostate Cancers Establishing a Cohort of African-American Men to Validate a Method for using Serial PSA Measures to Detect Aggressive Prostate Cancers James R. Hebert, Sc.D., Cancer Prevention and Control Program, University

More information

PSA I LOVE YOU: PROSTATE CANCER SCREENING IN IRELAND

PSA I LOVE YOU: PROSTATE CANCER SCREENING IN IRELAND PSA I LOVE YOU: PROSTATE CANCER SCREENING IN IRELAND Eimear Keane Fourth year Medicine, Trinity College Dublin Abstract Ireland has the second highest rate of prostate cancer (PCa) in Europe and this is

More information

The PSA Controversy: Defining It, Discussing It, and Coping With It

The PSA Controversy: Defining It, Discussing It, and Coping With It The PSA Controversy: Defining It, Discussing It, and Coping With It 11 TH ANNUAL SYMPOSIUM ON MEN S HEALTH June 12, 2013 The PSA Controversy Defining It, Discussing It and Coping With It As of May 2012,

More information

Prostate Cancer Screening: Phantom menace to society. Folusho Ogunfiditimi, DM, MPH, PA-C Vattikuti Urology Institute Henry Ford Health System

Prostate Cancer Screening: Phantom menace to society. Folusho Ogunfiditimi, DM, MPH, PA-C Vattikuti Urology Institute Henry Ford Health System Prostate Cancer Screening: Phantom menace to society Folusho Ogunfiditimi, DM, MPH, PA-C Vattikuti Urology Institute Henry Ford Health System Objectives USPTF Recommendations on PSA testing Justification

More information

PROSTATE CANCER UPDATE. Presenter: Bruce W. Porterfield, MD, PhD

PROSTATE CANCER UPDATE. Presenter: Bruce W. Porterfield, MD, PhD PROSTATE CANCER UPDATE DISCLOSURES I, BRUCE WAYNE PORTERFIELD HAVE NOTHING TO DISCLOSE. OBJECTIVES Epidemiology Early detection and screening Review of clinical disease states Treatment options by disease

More information

Thomas A. Kollmorgen, M.D. Oregon Urology Institute

Thomas A. Kollmorgen, M.D. Oregon Urology Institute Thomas A. Kollmorgen, M.D. Oregon Urology Institute None 240,000 new diagnosis per year, and an estimated 28,100 deaths (2012) 2 nd leading cause of death from cancer in U.S.A. Approximately 1 in 6 men

More information

Linköping University Post Print. Randomised prostate cancer screening trial: 20 year follow-up

Linköping University Post Print. Randomised prostate cancer screening trial: 20 year follow-up Linköping University Post Print Randomised prostate cancer screening trial: 20 year follow-up Gabriel Sandblom, Eberhard Varenhorst, Johan Rosell, Owe Lofman and Per Carlsson N.B.: When citing this work,

More information

PCa Commentary. Volume 73 January-February 2012 PSA AND TREATMENT DECISIONS:

PCa Commentary. Volume 73 January-February 2012 PSA AND TREATMENT DECISIONS: 1101 Madison Street Suite 1101 Seattle, WA 98104 P 206-215-2480 www.seattleprostate.com PCa Commentary Volume 73 January-February 2012 CONTENTS PSA SCREENING & BASIC SCIENCE PSA AND TREATMENT 1 DECISIONS

More information

Prostate Cancer Screening. A Decision Guide for African Americans

Prostate Cancer Screening. A Decision Guide for African Americans Prostate Cancer Screening A Decision Guide for African Americans This booklet was developed by the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC). Published

More information

Prostate Cancer Screening. A Decision Guide

Prostate Cancer Screening. A Decision Guide Prostate Cancer Screening A Decision Guide This booklet was developed by the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC). Is screening right for you?

More information

Overuse of PSA Screening for Prostate Cancer in Older Men. Elizabeth Jaramillo, MD January 17, 2014

Overuse of PSA Screening for Prostate Cancer in Older Men. Elizabeth Jaramillo, MD January 17, 2014 Overuse of PSA Screening for Prostate Cancer in Older Men Elizabeth Jaramillo, MD January 17, 2014 Screening Prostate cancer screening occurs in patients with no clinical sign or suspicion of disease Screening

More information

Guidance on Using Active Surveillance to Manage Men with Low-risk Prostate Cancer

Guidance on Using Active Surveillance to Manage Men with Low-risk Prostate Cancer Guidance on Using Active Surveillance to Manage Men with Low-risk Prostate Cancer Citation: Prostate Cancer Working Group and Ministry of Health. 2015. Guidance on Using Active Surveillance to Manage Men

More information

Role of MRI in the Diagnosis of Prostate Cancer, A Proposal

Role of MRI in the Diagnosis of Prostate Cancer, A Proposal Clinical and Experimental Medical Sciences, Vol. 1, 2013, no. 3, 111 116 HIKARI Ltd, www.m-hikari.com Role of MRI in the Diagnosis of Prostate Cancer, A Proposal W. Akhter Research Fellow Urology, Bartshealth

More information

What the U.S. Preventive Services Task Force Missed in Its Prostate Cancer Screening Recommendation

What the U.S. Preventive Services Task Force Missed in Its Prostate Cancer Screening Recommendation In the Balance 201207170 M12-0991 open early What the USPSTF Missed in Its Prostate Cancer Screening Recommendation What the U.S. Preventive Services Task Force Missed in Its Prostate Cancer Screening

More information

PSA Test Provides the Early Prostate Cancer Detection That Has Saved the Life of Thousands of Men

PSA Test Provides the Early Prostate Cancer Detection That Has Saved the Life of Thousands of Men PSA Test Provides the Early Prostate Cancer Detection That Has Saved the Life of Thousands of Men Table of Contents 1. What the research shows on the effectiveness of the PSA test p. 2 2. PSA test guidelines

More information

Analysis of Prostate Cancer at Easter Connecticut Health Network Using Cancer Registry Data

Analysis of Prostate Cancer at Easter Connecticut Health Network Using Cancer Registry Data The 2014 Cancer Program Annual Public Reporting of Outcomes/Annual Site Analysis Statistical Data from 2013 More than 70 percent of all newly diagnosed cancer patients are treated in the more than 1,500

More information

Draft Clinical Practice Guidelines. PSA Testing and Early Management of Test-Detected Prostate Cancer

Draft Clinical Practice Guidelines. PSA Testing and Early Management of Test-Detected Prostate Cancer Draft Clinical Practice Guidelines PSA Testing and Early Management of Test-Detected Prostate Cancer Draft November 2014 Prostate Cancer Foundation of Australia and Cancer Council Australia ISBN: This

More information

Official reprint from UpToDate www.uptodate.com 2013 UpToDate

Official reprint from UpToDate www.uptodate.com 2013 UpToDate Official reprint from UpToDate www.uptodate.com 2013 UpToDate The content on the UpToDate website is not intended nor recommended as a substitute for medical advice, diagnosis, or treatment. Always seek

More information

Clinical decision support based on practice guidelines: a business case on prostate cancer treatment

Clinical decision support based on practice guidelines: a business case on prostate cancer treatment Clinical decision support based on practice guidelines: a business case on prostate cancer treatment Denis PIERRE Denis PIERRE pierre@normind.com Ph. +33 (0)4 67 13 01 77 pierre@normind.com Ph. +33 (0)4

More information

Questions to Ask My Doctor About Prostate Cancer

Questions to Ask My Doctor About Prostate Cancer Questions to Ask My Doctor Being told you have prostate cancer can be scary and stressful. You probably have a lot of questions and concerns. Learning about the disease, how it s treated, and how this

More information

Preventive Care Guideline for Asymptomatic Low Risk Adults Age 18 through 64

Preventive Care Guideline for Asymptomatic Low Risk Adults Age 18 through 64 Preventive Care Guideline for Asymptomatic Low Risk Adults Age 18 through 64 1. BMI - Documented in patients medical record on an annual basis. Screen for obesity and offer intensive counseling and behavioral

More information

Key Messages for Healthcare Providers

Key Messages for Healthcare Providers Cancer Care Ontario: Prostate Cancer Screening with the Prostate- Specific Antigen (PSA) Test Key Messages for Healthcare Providers Considerations for men at average risk Avoid prostate-specific antigen

More information

Prostate Cancer Screening. Dr. J. McCracken, Urologist

Prostate Cancer Screening. Dr. J. McCracken, Urologist Prostate Cancer Screening Dr. J. McCracken, Urologist USPSTF Lifetime risk for diagnosis currently estimated at 15.9% Llifetime risk of dying of prostate cancer is 2.8% Seventy percent of deaths due to

More information

What are the evidence-based guidelines for prostate cancer screening?

What are the evidence-based guidelines for prostate cancer screening? TITLE: Prostate Cancer Screening: A Review of the Guidelines DATE: 29 November 2013 CONTEXT AND POLICY ISSUES Prostate cancer is the third leading cause of cancer death in Canadian men. 1 The lifetime

More information

See also: Web-Only CME quiz

See also: Web-Only CME quiz Guidance Statements Screening for Prostate Cancer: A Guidance Statement From the Clinical Guidelines Committee of the American College of Physicians Amir Qaseem, MD, PhD, MHA; Michael J. Barry, MD; Thomas

More information

Defending PSA Re-Thinking the USPSTF Recommendations for Prostate Cancer Screening Steven Bereta, MS, RN, FNP-C

Defending PSA Re-Thinking the USPSTF Recommendations for Prostate Cancer Screening Steven Bereta, MS, RN, FNP-C Defending PSA Re-Thinking the USPSTF Recommendations for Prostate Cancer Screening Steven Bereta, MS, RN, FNP-C Disclosure I do not have affiliations with any corporate organization that may constitute

More information

Prostate Cancer: Current Evidence Weighs Against Population Screening

Prostate Cancer: Current Evidence Weighs Against Population Screening Prostate Cancer: Current Evidence Weighs Against Population Screening Peter Boyle, PhD, DSc, President, International Prevention Research Institute, Lyon, France, and Otis W. Brawley, MD, Chief Medical

More information

Examining the Efficacy of Screening with Prostate- Specific Antigen Testing in Reducing Prostate Cancer Mortality

Examining the Efficacy of Screening with Prostate- Specific Antigen Testing in Reducing Prostate Cancer Mortality St. Catherine University SOPHIA Master of Arts in Nursing Theses Nursing 5-2012 Examining the Efficacy of Screening with Prostate- Specific Antigen Testing in Reducing Prostate Cancer Mortality Rachel

More information

Preventive Care Guideline for Asymptomatic Elderly Patients Age 65 and Over

Preventive Care Guideline for Asymptomatic Elderly Patients Age 65 and Over Preventive Care Guideline for Asymptomatic Elderly Patients Age 65 and Over 1. BMI - Documented in patients medical record on an annual basis up to age 74. Screen for obesity and offer counseling to encourage

More information

PROSTATE CANCER SCREENING PROSTATE CANCER SCREENING

PROSTATE CANCER SCREENING PROSTATE CANCER SCREENING 3:45 4:45pm Screening Guidelines for Men's Health SPEAKER Radha Rao, MD Presenter Disclosure Information The following relationships exist related to this presentation: Radha Rao, MD: No financial relationships

More information

Should I have a prostate-specific antigen (PSA) test to screen for prostate cancer? PATIENT DECISION AID

Should I have a prostate-specific antigen (PSA) test to screen for prostate cancer? PATIENT DECISION AID Should I have a prostate-specific antigen (PSA) test to screen for prostate cancer? PATIENT DECISION AID The prostate-specific antigen (PSA) test is a blood test that is used to screen for prostate cancer.

More information

PROSTATE CANCER. Normal-risk men: No family history of prostate cancer No history of prior screening Not African-American

PROSTATE CANCER. Normal-risk men: No family history of prostate cancer No history of prior screening Not African-American PROSTATE CANCER 1. Guidelines for Screening Risk Factors Normal-risk men: No family history of prostate cancer No history of prior screening Not African-American High-risk men: Family history of prostate

More information

Advice to patients about the PSA (prostate-specific antigen) blood test: frequently-asked questions

Advice to patients about the PSA (prostate-specific antigen) blood test: frequently-asked questions Advice to patients about the PSA (prostate-specific antigen) blood test: frequently-asked questions What is the PSA blood test? If you want more information before deciding to have this test, it is important

More information