Medical Doctor of the Clinical Research Department Sub-Investigator Centro de Investigaciones Metabólicas (CINME), Buenos Aires, Argentina.

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1 PERSONAL INFORMATION Full Name: GUSTAVO ADOLFO LO GIÚDICE Nationality: Argentine. License Number: UNIVERSITY DEGREES Internal Medicine Specialist Hospital San Bernardino de Siena & Internal Medicine Society of Buenos Aires. Buenos Aires University & Argentine Medical Association Diabetes & Nutrition Specialist Hospital de Clínicas José de San Martín, Buenos Aires University Internal Medicine Fellowship Hospital Marcial V. Quiroga. Ministry of Health of San Juan. San Juan, Argentina Doctor of Medicine (M.D.) Córdoba University Córdoba, Argentina. CURRENT POSITIONS 2011-present: 2011-present: 2008-present: Medical Doctor of the Clinical Research Department Sub-Investigator Centro de Investigaciones Metabólicas (CINME), Medical Doctor, out patient clinic Centro de Investigaciones Metabólicas (CINME), Medical Doctor, out patient clinic HMO O.S.P.A.C.P. Diabetes Department. 1

2 FORMER POSITIONS Centro Médico Viamonte Subinvestigator. Clinical Research Department Cordoba st, Director: Dr. Diego Aizenberg Centro Médico Viamonte Medical Doctor, out patient clinic 2019 Cordoba st, Medical Doctor, out patient clinic HMO O.S.E.C.A.C. Diabetes Department Medical Doctor, out patient clinic HMO O.S.P.E.R.Y.H. Diabetes Department Medical Doctor, Intensive Care Unit Clínica Integral San Isidro, Medical Doctor, out patient clinic Diabetes Department. Clínica Integral San Isidro Medical Doctor, out patient clinic Diabetes Department. C.I.A.D., Morón, Diabetes & Nutrition Fellowship Hospital de Clínicas José de San Martín Universidad de Director: Dr.Adolfo V. Zavala Clínica Psiquiátrica del Carmen Medical Doctor of Internal Patients. San Juan, Argentina. 2

3 EDUCATION Clinical Research 2013 BI Asp-3878 Investigator Result Meeting, on 1 February, London, UK. Novo Nordisk Pharma Basic Course in Good Clinical Practice F.E.F.y M. (Fundación de Estudios Farmacológicos y de Medicamentos) Director: Prof.Dr.Luis M. Zieher Duration: 17 hours Course of Remote Data Capture for CRAs, Parexel, October 17, Martínez, Buenos Aires Training Course of Source Document, Informed Consent Process, Patient Eligibility, Adverse Event/Serious Adverse Event/Safety Report, Investigational Product and Archiving/Site Regulatory Binder, Parexellent Site, Parexel, Dec 2008, Nutrition and Metabolism (Listener) 2012 XVIII Argentine Congress of Diabetes Sociedad Argentina de Diabetes, nd scientific sessions, American Diabetes Association, 8 al 12 de junio de 2012, Philadelphia, PA. (33 horas) Intensive Course of Endocrinology KECK University of Southern California, Dec 2011, Miami, Florida, U.S.A V National Meeting of Diabetes Sociedad Argentina de Diabetes, San Juan, Argentina XVII Argentine Congress of Diabetes Sociedad Argentina de Diabetes, Mar del Plata, Argentina The Latin America Congress on Controversies to Consensus in Diabetes, Obesity and Hypertension, CODHy, 2009 IV National Meeting of Diabetes Sociedad Argentina de Diabetes, Neuquén, Argentina. 3

4 2008 XVI Argentine Congress of Diabetes Sociedad Argentina de Diabetes, 2007 Autoinmunity & Endocrinology International Symposium Hospital Nacional de Clínicas José de San Martín, Universidad de 2007 Training in the Treatment of the Diabetes Type 1 y 2 Course Sociedad Argentina de Diabetes/ Sociedad Argentina de Nutrición Director: Dr. Luis Adolfo Grosembacher and Lic. María Emilia Mazzei (with paper and final evaluation) X Latin American Congress of Vasculopathy, Risk Factors & Diabetic Foot FUEDIN, Hospital Nacional de Clínicas José de San Martín, Universidad de 2005 IX Latin American Congress of Vasculopathy, Risk Factors & Diabetic Foot FUEDIN, Hospital Nacional de Clínicas José de San Martín, Universidad de 2004 Training in the Treatment of Diabetes Type 1 y 2 Course Sociedad Argentina de Diabetes/ Sociedad Argentina de Nutrición Director: Dr. Luis Adolfo Grosembacher y la Lic. María Emilia Mazzei (with paper and final evaluation) st Novo Nordisk Meeting of Internal Medicine Insulin Therapy Mar del Plata, Training & Updating in Diabetes and Nutrition Course Fundación Escuela en Diabetes y Nutrición, Hospital Nacional de Clinicas José de San Martín, Universidad de (246 Credits obtained). Director: Dr. Adolfo V. Zavala Controversial Topics in Diabetes Type 2 Course 2002 Treatment of Diabetes Type 2 Course 2002 Treatment of Hyperlipoproteinemia Course 4

5 2002 XIII Argentine Congress of Diabetes Sociedad Argentina de Diabetes, 2002 III Interstate Meeting of Nutrition & Training Exercise 2001 Interstate Internal Medicine Meeting Internal Medicine Society of Córdoba, Córdoba City, Argentina. Nutrition and Metabolism (Speaker) 2007 VIII Latin American Congress of Vasculopathy, Risk Factors & Diabetic Foot FUEDIN, Hospital Nacional de Clínicas José de San Martín, Universidad de 2003 Health Education Talks on Hypoglycemia & Hyperglycemia 2001 Training to Podiatrics About Diabetic Foot Novo Nordisk & Universidad de CLINICAL TRIALS: EXPERIENCE. - HAT- Survey for diabetic patient with insulin. Principal Investigator. Sponsor: Novo Nordisk. Center: Centro de Investigaciones Metabólicas (CINME). - BC Treatment of Type 2 Diabetes with oral agents. Sub-investigator. Sponsor: Roche. Center: Centro de Investigaciones Metabólicas (CINME). - WC Treatment of Type 2 Diabetes with oral agents. Sub-investigator. Sponsor: Roche. Center: Centro de Investigaciones Metabólicas (CINME). - CLAF- Treatment of Type 2 Diabetes with oral agents. Sub-investigator. Sponsor: Novartis. Center: Centro de Investigaciones Metabólicas (CINME). 5

6 - TAK Treatment of Type 2 Diabetes with oral agents. Sub-investigator. Sponsor: Takeda. Center: Centro de Investigaciones Metabólicas (CINME). - BIAJ- Treatment of Type 2 Diabetes with oral agents. Sub-investigator. Sponsor: Lilly s. Center: Centro de Investigaciones Metabólicas (CINME). - BiAsp 378 Treatment of Type 2 Diabetes with injection medication. Sub-investigator. Sponsor: Novo Nordisk Center: Centro de Investigaciones Metabólicas (CINME). - RESOLUTE - Treatment of Type 2 Diabetes with insulin. Principal Investigator. Sponsor: Sanofi Aventis. Center: Centro Médico Viamonte. - CACZ Treatment of Type 2 Diabetes with injection medication. Sub-investigator. Sponsor: Novartis Center: Centro Médico Viamonte. - BI Treatment of Type 2 Diabetes with oral agents. Sub-investigator. - BI Treatment of Type 2 Diabetes with oral agents. Sub-investigator. - D1690C Treatment of Type 2 Diabetes with oral agents. Sub-investigator. - BI Treatment of Type 2 Diabetes with oral agents. Sub-investigator. - CSPP100E2337-HTA and Kidney impared with oral agents. Sub-investigator. Sponsor: Novartis Center: Centro Médico Viamonte. - BI Treatment of Type 2 Diabetes with oral agents. Sub-investigator. - BI Treatment of Type 2 Diabetes with oral agents. Sub-investigator. - BI Treatment of Type 2 Diabetes with oral agents. Sub-investigator. - BI Treatment of Type 2 Diabetes with oral agents. Subinvestigator. - BI Treatment of Type 2 Diabetes with oral agents. Sub-investigator. 6

7 - BI Treatment of Type 2 Diabetes with oral agents. Sub-investigator. - D1680C Treatment of Type 2 Diabetes with oral agents. Sub-investigator. - D1680C Treatment of Type 2 Diabetes with oral agents. Sub-investigator. - D1680C00002 Treatment of Type 2 Diabetes with oral agents. Sub-investigator. 7

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