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1 2014 Rigshospitalet Videnskabelige publikationer 2014 Rigshospitalet

2 Abdominalcentret... 4 Centerfunktionen... 4 Anæstesi- og Operationsklinikken... 5 Hepatologisk klinik A... 9 Intensiv Terapiklinik Karkirurgisk klinik RK Kirurgisk gastroenterologisk klinik C Medicinsk gastroenterologisk klinik CA Nefrologisk klinik P Medicinsk Endokrinologisk Klinik PE Urologisk Klinik D Center for Klinisk Uddannelse / CEKU Det Nordiske Cochrane Center Copenhagen Trial Unit Det Nordiske Cochrane Center Diagnostisk Center Enhed for Genomisk Medicin Infektionshygiejnisk Enhed Klinisk Biokemisk Afdeling Klinik for Klinisk Fysiologi, Nuklearmedicin og PET Klinisk Immunologisk afdeling Klinisk Mikrobiologisk Afdeling Patologiafdelingen Radiologisk Klinik Finsencentret Center for Muskelforskning (CMRC) Finsenlaboratoriet Hæmatologisk Klinik Klinik for Infektionsmedicin og Reumatologi / Infektionsmedicinsk Klinik Klinik for Infektionsmedicin og Reumatologi / Reumatologisk Klinik Klinik for Infektionsmedicin og Reumatologi / Center for Inflammation og Metabolisme (CIM) og Center for Aktiv Sundhed (CFAS)

3 Klinik for Infektionsmedicin og Reumatologi / CHIP Onkologisk Klinik Hjertecentret Hjertemedicinsk Klinik Thoraxkirurgisk Klinik Thoraxanæstesiologisk Klinik HovedOrtoCentret Anæstesi- og operationsklinikken HOC Cochrane Anaesthesia Review Group, HOC Klinik for Ergo- og fysioterapi Klinik for Plastikkirurgi, Brystkirurgi og Brandsårsbehandling Ortopædkirurgisk Klinik Tand-mund-kæbekirurgisk Klinik Traumecenter og Akut Modtagelse Øre-næse-halskirurgisk og Audiologisk Klinik Juliane Marie Centret Anæstesi og Operationsklinikken BørneUngeKlinikken Enhed for Kirurgisk Patofysiologi Fertilitetsklinikken og Reproduktions Biologisk Laboratorium Gynækologisk Klinik Klinisk Genetisk Klinik Klinik for Psykologi, Pædagogik og Socialrådgivning Klinik for Vækst og Reproduktion Neonatalklinikken Obstetrisk Klinik Neurocentret Neuroanæstesiologisk Klinik Neurologisk Klinik Hukommelsesklinikken og Nationalt Videnscenter for Demens Dansk Multipel Sclerose Center Neurovaskulær Klinik

4 Neuromuskulær Klinik Neurobiologisk Forskningsenhed Neurokirurgisk Klinik Klinisk Neurofysiologisk Klinik Universitetshospitalernes Center for Sundhedsfaglig Forskning (UCSF)

5 Abdominalcentret Centerfunktionen Videnskabelige artikler Total intravenous anaesthesia versus inhalational anaesthesia for transabdominal robotic assisted laparoscopic surgery Herling, S. F., Dreijer, B., Thomsen, T. & Møller, A I : Cochrane Database of Systematic Reviews. Publikation: Forskning - peer review Review Who needs oral care? A study of potential factors associated with the need for oral care. Konradsen, H., Trosborg, I., Christensen, L., Thomsen, T. & Pedersen, P. U I : Journal of Nursing Education and Practice. 4, 11, s s. Female chronic pelvic pain is highly prevalent in Denmark. A cross-sectional population-based study. Loving, S., Thomsen, T., Jaszczak, P. & Nordling, J I : Scandinavian Journal of Pain. 5, 2, s Pelvic floor muscle dysfunctions are prevalent in female chronic pelvic pain: A cross-sectional populationbased study Loving, S., Thomsen, T., Jaszczak, P. & Nordling, J. okt 2014 I : European journal of pain (London, England). 18, 9, s s. Positive effect of protein-supplemented hospital food on protein intake in patients at nutritional risk: a randomised controlled trial Munk, T., Beck, A. M., Holst, M., Rosenbom, E., Rasmussen, H. H., Nielsen, M. A. & Thomsen, T. apr 2014 I : Journal of human nutrition and dietetics : the official journal of the British Dietetic Association. 27, 2, s s. Interventions for preoperative smoking cessation Thomsen, T., Villebro, N. & Møller, A I : Cochrane Database of Systematic Reviews. 3, s. CD

6 Anæstesi- og Operationsklinikken Videnskabelige artikler Cerebral oxygenation in health and disease Brassard, P., Ainslie, P. N. & Secher, N. H I : Frontiers in physiology. 5, s. 458 Beneficial effects of elevating cardiac preload on left-ventricular diastolic function and volume during heat stress: implications toward tolerance during a hemorrhagic insult Brothers, R. M., Pecini, R., Dalsgaard, M., Bundgaard-Nielsen, M., Wilson, T. E., Secher, N. H. & Crandall, C. G. 15 okt 2014 I : A J P: Regulatory, Integrative and Comparative Physiology (Online). 307, 8, s. R Detailed statistical analysis plan for the pulmonary protection trial Buggeskov, K. B., Jakobsen, J. C., Secher, N. H., Jonassen, T., Andersen, L. W., Steinbrüchel, D. A. & Wetterslev, J. 23 dec 2014 I : Trials. 15, 1, s. 510 Glucocorticoids improve high-intensity exercise performance in humans Casuso, R. A., Melskens, L., Bruhn, T., Secher, N. H. & Nordsborg, N. B I : European Journal of Applied Physiology. 114, 2, s Preoperative methylprednisolone enhances recovery after endovascular aortic repair: a randomized, doubleblind, placebo-controlled clinical trial de la Motte, L., Kehlet, H., Vogt, K., Nielsen, C. H., Rasmussen, J. B. G., Nielsen, H. M. B., Andersen, A., Schroeder, T. V. & Lönn, L. sep 2014 I : Annals of surgery. 260, 3, s s. Effect of phenylephrine vs. ephedrine on frontal lobe oxygenation during caesarean section with spinal anesthesia: an open label randomized controlled trial Foss, V. T., Christensen, R., Rokamp, K. Z., Nissen, P., Secher, N. H. & Nielsen, H. B I : Frontiers in physiology. 5, s. 81 Hyperventilation, Cerebral Perfusion and Syncope Immink, R. V., Pott, F. C., Secher, N. H. & Van Lieshout, J. J I : Journal of applied physiology (Bethesda, Md. : 1985). 116,7, Tracheal intubation with a flexible fibreoptic scope or the McGrath videolaryngoscope in simulated difficult airway scenarios: A randomised controlled manikin study Jepsen, C. H., Gätke, M. R., Thøgersen, B., Mollerup, L. T., Ruhnau, B., Rewers, M. & Rosenstock, C. V. mar 2014 I : European Journal of Anaesthesiology. 31, 3, s s. 5

7 Preserved frontal lobe oxygenation following calcium chloride for treatment of anesthesia-induced hypotension Kitchen, C-C., Nissen, P., Secher, N. H. & Nielsen, H. B I : Frontiers in physiology. 5, s. 407 Ischemic preconditioning of one forearm enhances static and dynamic apnea Kjeld, T., Rasmussen, M. R., Jattu, T., Nielsen, H. B. & Secher, N. H. jan 2014 I : Medicine and Science in Sports and Exercise. 46, 1, s s. Mesenterielt tranktionssyndrom Krohn, P. S., Ambrus, R., Zaar, M., Secher, N. H. & Svendsen, L. B. 17 feb 2014 I : Ugeskrift for læger [online]. 176, 8A, s. v Systemic, cerebral and skeletal muscle ketone body and energy metabolism during acute hyper-d-βhydroxybutyrataemia in post-absorptive healthy males Mikkelsen, K. H., Seifert, T., Secher, N. H., Grøndal, T. & van Hall, G. 21 nov 2014 I : The Journal of clinical endocrinology and metabolism. s. jc Maximal heart rate does not limit cardiovascular capacity in healthy humans: insight from right atrial pacing during maximal exercise Munch, G. D. W., Svendsen, J. H., Damsgaard, R., Secher, N. H., González-Alonso, J. & Mortensen, S. P I : The Journal of physiology. 592, s Systematic review of near-infrared spectroscopy determined cerebral oxygenation during non-cardiac surgery Nielsen, H. B I : Frontiers in physiology. 5, s. 93 Influence of intranasal and carotid cooling on cerebral temperature balance and oxygenation Nybo, L., Wanscher, M. & Secher, N. H I : Frontiers in physiology. 5, s. 79 A decrease in spatially resolved near-infrared spectroscopy-determined frontal lobe tissue oxygenation by phenylephrine reflects reduced skin blood flow Ogoh, S., Sato, K., Okazaki, K., Miyamoto, T., Secher, F., Sørensen, H., Rasmussen, P. & Secher, N. H. apr 2014 I : Anesthesia and Analgesia. 118, 4, s s. Case report: (Pre)syncopal symptoms associated with a negative internal jugular venous pressure Olesen, N., van Lieshout, J. J., Fisher, J. P., Seifert, T., Nielsen, H. B. & Secher, N. H I : Frontiers in physiology. 5, s

8 The hydrostatic pressure indifference point underestimates orthostatic redistribution of blood in humans Petersen, L. G., Carlsen, J. F., Nielsen, M. B., Damgaard, M. & Secher, N. H I : Journal of applied physiology (Bethesda, Md. : 1985). 116, s Association between intramuscular fat in the arm following arm training and INSIG2 Popadic Gacesa, J. Z., Secher, N. H., Momcilovic, M. & Grujic, N. G I : Scandinavian journal of medicine & science in sports. 24, 6, Hydroxyethyl Starch Reduces Coagulation Competence and Increases Blood Loss During Major Surgery: Results From a Randomized Controlled Trial Rasmussen, K., Johansson, P. I., Højskov, M., Kridina, I., Kistorp, T., Thind, P., Nielsen, H., Ruhnau, B., Pedersen, T. S. & Secher, N. H I : Annals of surgery. 259, 2, s s. O2 supplementation to secure the near-infrared spectroscopy determined brain and muscle oxygenation in vascular surgical patients: a presentation of 100 cases Rokamp, K. Z., Secher, N. H., Eiberg, J., Lønn, L. & Nielsen, H. M. B I : Frontiers in physiology. 5, s. e Glycopyrrolate does not influence the visual or motor-induced increase in regional cerebral perfusion Rokamp, K. Z., Olesen, N., Larsson, H. B. W., Hansen, A. E., Seifert, T., Nielsen, H. B., Secher, N. H. & Rostrup, E I : Frontiers in physiology. 5, s. 45 Metabolic and mechanical involvement of arms and legs in simulated double pole skiing Rud, B., Secher, N. H., Nilsson, J., Smith, G. & Hallén, J I : Scandinavian journal of medicine & science in sports. 24, 6, Inhale your blood volume! Secher, N. H. 1 okt 2014 I : Experimental Physiology. 99, 10, s Ventilatory strategy during liver transplantation: implications for near-infrared spectroscopy-determined frontal lobe oxygenation Sørensen, H., Grocott, H. P., Niemann, M., Rasmussen, A., Hillingsø, J. G., Frederiksen, H. J. & Secher, N. H I : Frontiers in physiology. 5, s. 321 External carotid artery flow maintains near infrared spectroscopy-determined frontal lobe oxygenation during ephedrine administration Sørensen, H., Rasmussen, P., Sato, K., Persson, S., Olesen, N. D., Nielsen, H. B., Olsen, N. V., Ogoh, S. & Secher, N. H. 6 feb 2014 I : British Journal of Anaesthesia. 1 7

9 Dehydration affects cerebral blood flow but not its metabolic rate for oxygen during maximal exercise in trained humans Trangmar, S. J., Chiesa, S. T., Stock, C. G., Kalsi, K. K., Secher, N. H. & González-Alonso, J. 15 jul 2014 I : The Journal of physiology. 592, Pt 14, s s. One-week postoperative patency of lower extremity in situ bypass graft comparing epidural and general anesthesia: retrospective study of 822 patients Wiis, J. T., Jensen-Gadegaard, P., Altintas, Ü., Seidelin, C., Martusevicius, R. & Mantoni, T. feb 2014 I : Annals of Vascular Surgery. 28, 2, s s. Coagulation competence and fluid recruitment after moderate blood loss in young men Zaar, M., Mørkeberg, J., Pott, F. C., Johansson, P. I. & Secher, N. H. sep 2014 I : Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis. 25, 6, s s. Identifikation af et mesenterielt traktionssyndrom med laserkontrastundersøgelse Zaar, M., Secher, N. H., Tollund, C., Mortensen, C. R. & Svendsen, L. B. 7 apr 2014 I : Ugeskrift for læger [online]. 176, 15, s. v

10 Hepatologisk klinik A Videnskabelige artikler Levercirrose Bendtsen, F., Larsen, F. S., Ott, P. & Vilstrup, H. 17 feb 2014 I : Ugeskrift for læger [online]. 176, 4 Historical epidemiology of hepatitis C virus (HCV) in selected countries Bruggmann, P., Berg, T., Øvrehus, A. L. H., Moreno, C., Brandão Mello, C. E., Roudot-Thoraval, F., Marinho, R. T., Sherman, M., Ryder, S. D., Sperl, J., Akarca, U., Balık, I., Bihl, F., Bilodeau, M., Blasco, A. J., Buti, M., Calinas, F., Calleja, J. L., Cheinquer, H., Christensen, P. B., Clausen, M., Coelho, H. S. M., Cornberg, M., Cramp, M. E., Dore, G. J., Doss, W., Duberg, A. S., El-Sayed, M. H., Ergör, G., Esmat, G., Estes, C., Falconer, K., Félix, J., Ferraz, M. L. G., Ferreira, P. R., Frankova, S., García-Samaniego, J., Gerstoft, J., Giria, J. A., Gonçales, F. L., Gower, E., Gschwantler, M., Guimarães Pessôa, M., Hézode, C., Hofer, H., Husa, P., Idilman, R., Kåberg, M., Kaita, K. D. E., Kautz, A., Kaymakoglu, S., Krajden, M., Krarup, H., Laleman, W., Lavanchy, D., Lázaro, P., Marotta, P., Mauss, S., Mendes Correa, M. C., Müllhaupt, B., Myers, R. P., Negro, F., Nemecek, V., Örmeci, N., Parkes, J., Peltekian, K. M., Ramji, A., Razavi, H., Reis, N., Roberts, S. K., Rosenberg, W. M., Sarmento-Castro, R., Sarrazin, C., Semela, D., Shiha, G. E., Sievert, W., Stärkel, P., Stauber, R. E., Thompson, A. J., Urbanek, P., van Thiel, I., Van Vlierberghe, H., Vandijck, D., Vogel, W., Waked, I., Wedemeyer, H., Weis, N., Wiegand, J., Yosry, A., Zekry, A., Van Damme, P., Aleman, S. & Hindman, S. J. maj 2014 I : Journal of viral hepatitis. 21 Suppl 1, s s. Hepatitis B infektion hos børn Christensen, V. B., Nordly, S., Kjær, M. & Jørgensen, M. H. 14 apr 2014 I : Ugeskrift for læger [online]. 176, 8, s. V Hepatitis C infektion hos børn Christensen, V. B., Nordly, S., Fischler, B., Kjær, M. S. & Jørgensen, M. H. 14 apr 2014 I : Ugeskrift for læger [online]. 176, 8, s. V Forhøjet alaninaminotransferase hos en 4-årig som et tidligt tegn på autoimmun hepatitis Jørgensen, M. H., Christensen, V. B. & Clemmesen, J. O. 14 apr 2014 I : Ugeskrift for læger [online]. 176, 8, s. V Understanding paracetamol-induced liver failure Larsen, F. S. & Wendon, J. jun 2014 I : Intensive Care Medicine. 40, 6, s s. Association of markers of bacterial translocation with immune activation in decompensated cirrhosis Mortensen, C., Jensen, J. S., Hobolth, L., Dam-Larsen, S., Madsen, E. B., Andersen, O., Møller, S. & Bendtsen, F. dec 2014 I : European journal of gastroenterology & hepatology. 26, 12, s s. 9

11 The present and future disease burden of hepatitis C virus (HCV) infection with today's treatment paradigm Razavi, H., Waked, I., Sarrazin, C., Myers, R. P., Idilman, R., Calinas, F., Vogel, W., Mendes Correa, M. C., Hézode, C., Lázaro, P., Akarca, U., Aleman, S., Balık, I., Berg, T., Bihl, F., Bilodeau, M., Blasco, A. J., Brandão Mello, C. E., Bruggmann, P., Buti, M., Calleja, J. L., Cheinquer, H., Christensen, P. B., Clausen, M., Coelho, H. S. M., Cramp, M. E., Dore, G. J., Doss, W., Duberg, A. S., El-Sayed, M. H., Ergör, G., Esmat, G., Falconer, K., Félix, J., Ferraz, M. L. G., Ferreira, P. R., Frankova, S., García-Samaniego, J., Gerstoft, J., Giria, J. A., Gonçales, F. L., Gower, E., Gschwantler, M., Guimarães Pessôa, M., Hindman, S. J., Hofer, H., Husa, P., Kåberg, M., Kaita, K. D. E., Kautz, A., Kaymakoglu, S., Krajden, M., Krarup, H., Laleman, W., Lavanchy, D., Marinho, R. T., Marotta, P., Mauss, S., Moreno, C., Murphy, K., Negro, F., Nemecek, V., Örmeci, N., Øvrehus, A. L. H., Parkes, J., Pasini, K., Peltekian, K. M., Ramji, A., Reis, N., Roberts, S. K., Rosenberg, W. M., Roudot-Thoraval, F., Ryder, S. D., Sarmento-Castro, R., Semela, D., Sherman, M., Shiha, G. E., Sievert, W., Sperl, J., Stärkel, P., Stauber, R. E., Thompson, A. J., Urbanek, P., Van Damme, P., van Thiel, I., Van Vlierberghe, H., Vandijck, D., Wedemeyer, H., Weis, N., Wiegand, J., Yosry, A., Zekry, A., Cornberg, M., Müllhaupt, B. & Estes, C. maj 2014 I : Journal of viral hepatitis. 21 Suppl 1, s s. Dietary advices on carbohydrate intake for pregnant women with type 1 diabetes Roskjær, A. B., Andersen, J. R., Ronneby, H., Damm, P. & Mathiesen, E. R. 5 jun 2014 I : The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. s s. Nationwide experience of treatment with protease inhibitors in chronic hepatitis C patients in denmark: identification of viral resistance mutations Sølund, C., Krarup, H., Ramirez, S., Thielsen, P., Røge, B. T., Lunding, S., Barfod, T. S., Madsen, L. G., Tarp, B. D., Christensen, P. B., Gerstoft, J., Laursen, A. L., Bukh, J., Weis, N., DANHEP group & Clausen, M. R I : P L o S One. 9, 12, s. e Strategies to manage hepatitis C virus (HCV) disease burden Wedemeyer, H., Duberg, A. S., Buti, M., Rosenberg, W. M., Frankova, S., Esmat, G., Örmeci, N., Van Vlierberghe, H., Gschwantler, M., Akarca, U., Aleman, S., Balık, I., Berg, T., Bihl, F., Bilodeau, M., Blasco, A. J., Brandão Mello, C. E., Bruggmann, P., Calinas, F., Calleja, J. L., Cheinquer, H., Christensen, P. M., Clausen, M., Coelho, H. S. M., Cornberg, M., Cramp, M. E., Dore, G. J., Doss, W., El-Sayed, M. H., Ergör, G., Estes, C., Falconer, K., Félix, J., Ferraz, M. L. G., Ferreira, P. R., García-Samaniego, J., Gerstoft, J., Giria, J. A., Gonçales, F. L., Guimarães Pessôa, M., Hézode, C., Hindman, S. J., Hofer, H., Husa, P., Idilman, R., Kåberg, M., Kaita, K. D. E., Kautz, A., Kaymakoglu, S., Krajden, M., Krarup, H., Laleman, W., Lavanchy, D., Lázaro, P., Marinho, R. T., Marotta, P., Mauss, S., Mendes Correa, M. C., Moreno, C., Müllhaupt, B., Myers, R. P., Nemecek, V., Øvrehus, A. L. H., Parkes, J., Peltekian, K. M., Ramji, A., Razavi, H., Reis, N., Roberts, S. K., Roudot-Thoraval, F., Ryder, S. D., Sarmento-Castro, R., Sarrazin, C., Semela, D., Sherman, M., Shiha, G. E., Sperl, J., Stärkel, P., Stauber, R. E., Thompson, A. J., Urbanek, P., Van Damme, P., van Thiel, I., Vandijck, D., Vogel, W., Waked, I., Weis, N., Wiegand, J., Yosry, A., Zekry, A., Negro, F., Sievert, W. & Gower, E. maj 2014 I : Journal of viral hepatitis. 21 Suppl 1, s s. Nutritional intake and status in persons with alcohol dependency: data from an outpatient treatment programme Wilkens Knudsen, A., Jensen, J-E. B., Nordgaard-Lassen, I., Almdal, T., Kondrup, J. & Becker, U. okt 2014 I : European Journal of Nutrition. 53, 7, s s. 10

12 Intensiv Terapiklinik Disputatser og Ph.d.-afhandlinger Sulfopro: a pharmacoepidemiological survey of the cardiovascular risk of sulfonylurea treatment and use of secondary prevention pharmacotherapy after first myocardial infarction in patients with diabetes mellitus Jørgensen, C. H Eget Forlag. 59 s. Publikation: Forskning Ph.d.-afhandling Videnskabelige artikler Acute onset and rapid progression of multiple organ failure in a young adult with undiagnosed disseminated colonic adenocarcinoma Frestad, D., Perner, A. & Pedersen, U. G I : B M J Case Reports. 2014, s. bcr Stress ulcer prophylaxis versus placebo or no prophylaxis in critically ill patients: A systematic review of randomised clinical trials with meta-analysis and trial sequential analysis Krag, M., Perner, A., Wetterslev, J., Wise, M. P. & Hylander Møller, M I : Intensive Care Medicine. 40, 1, s Pulmonary Pathophysiology in Another Galaxy Plovsing, R. R. & Berg, R. M. G I : Anesthesiology. 120, 1, s Red blood cell transfusion in septic shock - clinical characteristics and outcome of unselected patients in a prospective, multicentre cohort Rosland, R. G., Hagen, M. U., Haase, N., Holst, L. B., Plambech, M., Madsen, K. R., Søe-Jensen, P., Poulsen, L. M., Bestle, M. & Perner, A I : Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. 22, 14 s. Cytokine and nitric oxide levels in patients with sepsis--temporal evolvement and relation to platelet mitochondrial respiratory function Sjövall, F., Morota, S., Frostner, E. Å., Hansson, M. J. & Elmér, E I : P L o S One. 9, 7, s. e Progressive intracranial hypertension and cerebral hypoperfusion in a fatal case of cerebral aspergilloma Toksvang, L. N., Plovsing, R. R. & Berg, R. M. G I : B M J Case Reports. 2014, s. bcr Mortality and postoperative care pathways after emergency gastrointestinal surgery in 2904 patients: A population-based cohort study Vester-Andersen, M., Lundstrøm, L. H., Møller, M. H., Waldau, T., Rosenberg, J. & Møller, A I : British Journal of Anaesthesia. 112, 5, s

13 Platelet aggregation following trauma: a prospective study Windeløv, N. A., Sørensen, A. M., Perner, A., Wanscher, M., Larsen, C. F., Ostrowski, S. R., Johansson, P. I. & Rasmussen, L. S I : Blood Coagulation and Fibrinolysis. 25, 1, s s. Ultrasound-guided nerve blocks - is documentation and education feasible using only text and pictures? Worm, B. S., Krag, M. & Jensen, K I : P L o S One. 9, 2, s. e86966 Rocuronium blockade reversal with sugammadex vs. neostigmine: randomized study in Chinese and Caucasian subjects Wu, X., Oerding, H., Liu, J., Vanacker, B., Yao, S., Dahl, V., Xiong, L., Claudius, C., Yue, Y., Huang, Y., Abels, E., Rietbergen, H. & Woo, T I : B M C Anesthesiology. 14, s. 53 Hydroxyethyl starch in sepsis Haase, N. R. S. jan 2014 I : Danish Medical Bulletin (Online). 61, 1, s. B4764 Hydroxyethyl starch: putting patient safety first Bion, J., Bellomo, R., Myburgh, J., Perner, A., Reinhart, K. & Finfer, S. feb 2014 I : Intensive Care Medicine. 40, 2, s s. Open Letter to the Executive Director of the European Medicines Agency concerning the licensing of hydroxyethyl starch solutions for fluid resuscitation Bellomo, R., Bion, J., Finfer, S., Myburgh, J., Perner, A. & Reinhart, K. mar 2014 I : Acta anaesthesiologica Scandinavica. 58, 3, s s. Open letter to the Executive Director of the European Medicines Agency concerning the licensing of hydroxyethyl starch solutions for fluid resuscitation Bellomo, R., Bion, J., Finfer, S., Myburgh, J., Perner, A., Reinhart, K. & all co-signatories mar 2014 I : British Journal of Anaesthesia. 112, 3, s s. Guideline for stress ulcer prophylaxis in the intensive care unit Madsen, K. R., Lorentzen, K., Clausen, N., Oberg, E., Kirkegaard, P. R. C., Maymann-Holler, N., Møller, M. H. & Danish Society of Intensive Care Medicine mar 2014 I : Danish Medical Bulletin (Online). 61, 3, s. C4811 Collaborative strategies for teaching common acid-base disorders to medical students Petersen, M. W., Toksvang, L. N., Plovsing, R. R. & Berg, R. M. G. mar 2014 I : Advances in Physiology Education. 38, 1, s s. 12

14 Mortality in patients with hypovolemic shock treated with colloids or crystalloids Perner, A., Haase, N. & Wetterslev, J. 12 mar 2014 I : JAMA : the journal of the American Medical Association. 311, 10, s Publikation: Forskning - peer review Letter Understanding hypovolaemia Perner, A. & De Backer, D. apr 2014 I : Intensive Care Medicine. 40, 4, s s. Long-term outcomes in patients with severe sepsis randomised to resuscitation with hydroxyethyl starch 130/0.42 or Ringer's acetate Perner, A., Haase, N., Winkel, P., Guttormsen, A. B., Tenhunen, J., Klemenzson, G., Müller, R. G., Aneman, A. & Wetterslev, J. 8 maj 2014 I : Intensive Care Medicine. 40, 7, s Individual patient data meta-analysis of hydroxyethyl starch 130/ versus crystalloid for fluid resuscitation in patients with severe sepsis: a statistical analysis plan Hammond, N. E., Haase, N., Billot, L., Wetterslev, J., Saxena, M. K., Finfer, S., Perner, A. & Myburgh, J. jun 2014 I : Critical Care and Resuscitation. 16, 2, s s. Association between sympathoadrenal activation, fibrinolysis, and endothelial damage in septic patients: a prospective study Johansson, P. I., Haase, N., Perner, A. & Ostrowski, S. R. jun 2014 I : Journal of Critical Care. 29, 3, s s. Væskebehandling med kolloider set fra et anæstesiologisk og intensivmedicinsk perspektiv Stensballe, J. & Perner, A. 2 jun 2014 I : Ugeskrift for læger [online]. 176, 11A Influence of body mass index on mortality after surgery for perforated peptic ulcer Buck, D. L., Møller, M. H. & Danish Clinical Register of Emergency Surgery jul 2014 I : The British journal of surgery. 101, 8, s s. Transcompartmental inflammatory responses in humans: IV versus endobronchial administration of endotoxin* Plovsing, R. R., Berg, R. M. G., Evans, K. A., Konge, L., Iversen, M., Garred, P. & Møller, K. jul 2014 I : Critical Care Medicine. 42, 7, s s. High versus low blood-pressure target in septic shock Berg, R. M. G., Plovsing, R. R. & Møller, K. 17 jul 2014 I : The New England journal of medicine. 371, 3, s. 282 Publikation: Forskning - peer review Letter 13

15 Effect of valproic acid and injury on lesion size and endothelial glycocalyx shedding in a rodent model of isolated traumatic brain injury Jepsen, C. H., demoya, M. A., Perner, A., Sillesen, M., Ostrowski, S. R., Alam, H. B. & Johansson, P. I. aug 2014 I : The journal of trauma and acute care surgery. 77, 2, s s. Poor agreement between transcranial Doppler and near-infrared spectroscopy-based estimates of cerebral blood flow changes in sepsis Toksvang, L. N., Plovsing, R. R., Petersen, M. W., Møller, K. & Berg, R. M. G. sep 2014 I : Clinical physiology and functional imaging. 34, 5, s s. Lower versus Higher Hemoglobin Threshold for Transfusion in Septic Shock Holst, L. B., Haase, N., Wetterslev, J., Wernerman, J., Guttormsen, A. B., Karlsson, S., Johansson, P. I., Aneman, A., Vang, M. L., Winding, R., Nebrich, L., Nibro, H. L., Rasmussen, B. S., Lauridsen, J. R. M., Nielsen, J. S., Oldner, A., Pettilä, V., Cronhjort, M. B., Andersen, L. H., Gøttrup Pedersen, U., Reiter, N., Wiis, J., White, J. O., Russell, L., Thornberg, K. J., Hjortrup, P. B., Müller, R. G., Møller, M. H., Steensen, M., Tjäder, I., Kilsand, K., Odeberg-Wernerman, S., Sjøbø, B., Bundgaard, H. M. H., Thyø, M. A., Lodahl, D., Mærkedahl, R., Albeck, C., Illum, D., Kruse, M., Winkel, P., Perner, A. & the TRISS Trial Group and the Scandinavian Critical Care Trials Group 1 okt 2014 I : The New England journal of medicine. 371, 15, s Low level of procoagulant platelet microparticles is associated with impaired coagulation and transfusion requirements in trauma patients Windeløv, N. A., Johansson, P. I., Sørensen, A. M., Perner, A., Wanscher, M., Larsen, C. F., Ostrowski, S. R. & Rasmussen, L. S. nov 2014 I : The journal of trauma and acute care surgery. 77, 5, s s. Thromboelastography in patients with severe sepsis: a prospective cohort study Haase, N., Ostrowski, S. R., Wetterslev, J., Lange, T., Møller, M. H., Tousi, H., Steensen, M., Pott, F., Søe-Jensen, P., Nielsen, J., Hjortrup, P. B., Johansson, P. I. & Perner, A. 21 nov 2014 I : Intensive Care Medicine. 41, s Ebola virus disease: clinical care and patient-centred research Roberts, I. & Perner, A. 6 dec 2014 I : Lancet. 384, 9959, s s. Acute kidney injury with hydroxyethyl starch 130/0.42 in severe sepsis Müller, R. B., Haase, N., Lange, T., Wetterslev, J. & Perner, A. 18 dec 2014 I : Acta anaesthesiologica Scandinavica. 59, s

16 Karkirurgisk klinik RK Disputatser og Ph.d.-afhandlinger Abdominal aortic aneurysm surveillance - the added value of 3D and contrast-enhanced ultrasound Bredahl, K Eget forlag Københavns University. Publikation: Forskning Ph.d.-afhandling Videnskabelige artikler Regarding "Progression of asymptomatic carotid stenosis despite optimal medical therapy" Abbott, A., Geroulakos, G., Mikhailidis, D. P., Nicolaides, A. N., Sillesen, H. & Veith, F. J. jun 2014 I : Journal of Vascular Surgery. 59, 6, s s. Effect of high-dose atorvastatin on renal function in subjects with stroke or transient ischemic attack in the SPARCL trial Amarenco, P., Callahan, A., Campese, V. M., Goldstein, L. B., Hennerici, M. G., Messig, M., Sillesen, H., Welch, K. M. A., Wilson, D. & Zivin, J. A. okt 2014 I : Stroke; a journal of cerebral circulation. 45, 10, s s. Endovascular repair of acute uncomplicated aortic type B dissection promotes aortic remodelling: 1 year results of the ADSORB trial Brunkwall, J., Kasprzak, P. L., Verhoeven, E., Heijmen, R., Taylor, P., Alric, P., Canaud, L., Janotta, M., Raithel, D., Malina, W., Resch, T., Eckstein, H-H., Ockert, S., Larzon, T., Carlsson, F., Schumacher, H., Classen, S., Schaub, P., Lammer, J., Lönn, L., Clough, R. E., Rampoldi, V., Trimarchi, S., Fabiani, J-N., Böckler, D., Kotelis, D., Böckler, D., Kotelis, D., von Tenng-Kobligk, H., Mangialardi, N., Ronchey, S., Dialetto, G., Matoussevitch, V. & ADSORB Trialists sep 2014 I : European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. 48, 3, s s. Accuracy of visual scoring and semi-quantification of ultrasound strain elastography - a phantom study Carlsen, J. F., Ewertsen, C., Saftoiu, A., Lönn, L. & Nielsen, M. B I : P L o S One. 9, 2, s. e88699 Management of placenta percreta: a review of published cases Clausen, C., Lönn, L. & Langhoff-Roos, J I : Acta Obstetricia et Gynecologica Scandinavica. 93, 2, s Perioperative blood transfusion does not decrease survival after surgical treatment of spinal metastases Clausen, C., Lönn, L., Morgen, S. S., Nielsen, M. B., Frevert, S. C., Johansson, P. I. & Dahl, B. aug 2014 I : European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 23, 8, s s. 15

17 New insights regarding the incidence, presentation and treatment options of aorto-oesophageal fistulation after thoracic endovascular aortic repair: the European Registry of Endovascular Aortic Repair Complications Czerny, M., Eggebrecht, H., Sodeck, G., Weigang, E., Livi, U., Verzini, F., Schmidli, J., Chiesa, R., Melissano, G., Kahlberg, A., Amabile, P., Harringer, W., Horacek, M., Erbel, R., Park, K-H., Beyersdorf, F., Rylski, B., Blanke, P., Canaud, L., Khoynezhad, A., Lönn, L., Rousseau, H., Trimarchi, S., Brunkwall, J., Gawenda, M., Dong, Z., Fu, W., Schuster, I. & Grimm, M I : European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 45, 3, s Preoperative methylprednisolone enhances recovery after endovascular aortic repair: a randomized, doubleblind, placebo-controlled clinical trial de la Motte, L., Kehlet, H., Vogt, K., Nielsen, C. H., Rasmussen, J. B. G., Nielsen, H. M. B., Andersen, A., Schroeder, T. V. & Lönn, L I : Annals of surgery. 260, 3, s s. Vascular and Endovascular Controversies de la Motte, L., Jensen, L. P., Vogt, K. C., Schroeder, T. V. & Lönn, L Outcomes of EVAR in the Danish cohort study 2007 to Greenhalgh, R. M. (red.). London: Biba Medical Publikation: Formidling Bidrag til bog/antologi Reproducibility of two 3-D ultrasound carotid plaque quantification methods Græbe, M., Entrekin, R., Collet-Billon, A., Harrison, G. & Sillesen, H. jul 2014 I : Ultrasound in Medicine & Biology. 40, 7, s s. Melatonin reduces cardiac morbidity and markers of myocardial ischemia after elective abdominal aortic aneurism repair: a randomized, placebo-controlled, clinical trial Gögenur, I., Kücükakin, B., Panduro Jensen, L., Reiter, R. J. & Rosenberg, J. aug 2014 I : Journal of Pineal Research. 57, 1, s s. Clinical evaluation of synthetic aperture sequential beamforming ultrasound in patients with liver tumors Hansen, P. M., Hemmsen, M., Brandt, A., Rasmussen, J., Lange, T., Krohn, P. S., Lönn, L., Jensen, J. A. & Nielsen, M. B. dec 2014 I : Ultrasound in Medicine & Biology. 40, 12, s s. The management of ruptured abdominal aortic aneurysms Larzon, T., Falkenberg, M. & Lönn, L. apr 2014 I : Journal of Cardiovascular Surgery. 55, 2, s s. Volume flow in arteriovenous fistulas using vector velocity ultrasound Møller Hansen, P., Olesen, J. B., Pihl, M. J., Lange, T., Heerwagen, S., Pedersen, M. M., Rix, M., Lönn, L., Jensen, J. A. & Nielsen, M. B I : Ultrasound Med.Biol.40, 11, s s. 16

18 Clinical and imaging features associated with an increased risk of late stroke in patients with asymptomatic carotid disease Naylor, A. R., Schroeder, T. V. & Sillesen, H. dec 2014 I : European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. 48, 6, s s. Prediction of major vascular events after stroke: the stroke prevention by aggressive reduction in cholesterol levels trial Ovbiagele, B., Goldstein, L. B., Amarenco, P., Messig, M., Sillesen, H., Callahan, A., Hennerici, M. G., Zivin, J., Welch, K. M. A. & SPARCL Investigators apr 2014 I : Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 23, 4, s s. Novel flow quantification of the carotid bulb and the common carotid artery with vector flow ultrasound Pedersen, M. M., Pihl, M. J., Haugaard, P., Hansen, K. L., Lange, T., Lönn, L., Nielsen, M. B. & Jensen, J. A. nov 2014 I : Ultrasound in Medicine & Biology. 40, 11, s s. Editor's choice - Safety of carotid endarterectomy after intravenous thrombolysis for acute ischaemic stroke: a case-controlled multicentre registry study Rathenborg, L. K., Venermo, M., Troëng, T., Jensen, L. P., Vikatmaa, P., Wahlgren, C., Ijäs, P., Björck, M. & Kragsterman, B. dec 2014 I : European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. 48, 6, s s. Commentary on "Comparison of cognitive function after carotid artery stenting versus carotid endarterectomy" Rathenborg, L. K. mar 2014 I : European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. 47, 3, s. 232 Publikation: Forskning - peer review Kommentar/debat O2 supplementation to secure the near-infrared spectroscopy determined brain and muscle oxygenation in vascular surgical patients: a presentation of 100 cases Rokamp, K. Z., Secher, N. H., Eiberg, J., Lønn, L. & Nielsen, H. M. B I : Frontiers in physiology. 5, s. e Association between endovascular performance in a simulated setting and in the catheterization laboratory Räder, S. B. E. W., Abildgaard, U., Jørgensen, E., Bech, B., Lönn, L. & Ringsted, C. V. aug 2014 I : Simulation in healthcare : journal of the Society for Simulation in Healthcare. 9, 4, s s. A study of the effect of dyad practice versus that of individual practice on simulation-based complex skills learning and of students' perceptions of how and why dyad practice contributes to learning Räder, S. B. E. W., Henriksen, A-H., Butrymovich, V., Sander, M., Jørgensen, E., Lönn, L. & Ringsted, C. V. sep 2014 I : Academic medicine : journal of the Association of American Medical Colleges. 89, 9, s s. 17

19 Carotid intima-media thickness and/or carotid plaque: what is relevant? Sillesen, H. aug 2014 I : European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. 48, 2, s s. Atherogenic dyslipidemia and residual cardiovascular risk in statin-treated patients Sirimarco, G., Labreuche, J., Bruckert, E., Goldstein, L. B., Fox, K. M., Rothwell, P. M., Amarenco, P., PERFORM and SPARCL Investigators and Committees & Sillesen, H. H. maj 2014 I : Stroke; a journal of cerebral circulation. 45, 5, s s. Response to letter to the editor: 'Re: Endograft limb occlusion in EVAR: iliac tortuosity quantified by three different indices on the basis of pre-operative CTA' Taudorf, M., Schroeder, T. V. & Lönn, L. dec 2014 I : European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. 48, 6, s. 712 Endograft limb occlusion in EVAR: iliac tortuosity quantified by three different indices on the basis of preoperative CTA Taudorf, M., Jensen, L. P., Vogt, K. C., Rasmussen, J. B. G., Schroeder, T. V. & Lönn, L. nov 2014 I : European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. 48, 5, s s. The assessment of clinical skills is imperative in postgraduate specialty training Tolsgaard, M. G., Ostergaard, D., Konge, L., Schroeder, T. V. & Ringsted, C. 15 sep 2014 I : Ugeskrift for læger [online]. 176, 38, s s. One-week postoperative patency of lower extremity in situ bypass graft comparing epidural and general anesthesia: retrospective study of 822 patients Wiis, J. T., Jensen-Gadegaard, P., Altintas, Ü., Seidelin, C., Martusevicius, R. & Mantoni, T. feb 2014 I : Annals of Vascular Surgery. 28, 2, s s. 18

20 Kirurgisk gastroenterologisk klinik C Disputatser og Ph.d.-afhandlinger Immunosuppressive polyclonal and monoclonal T-cell antibody induction therapy for solid organ transplant recipients: systematic reviews with meta-analyses and trial sequential analyses of randomised clinical trials Penninga, L. 31 okt 2014 København: København: Eget forlag. 52 s. Publikation: Forskning Ph.d.-afhandling Videnskablige artikler Nutidige og fremtidige aspekter ved robotkirurgi inden for øsofagus-ventrikel cancer Achiam, M. P., Jendresen, M. & Svendsen, L. B. 3 feb 2014 I : Ugeskrift for læger [online]. 176, 3 Radiofrekvensablation reducerer risikoen ved dysplastisk Barrett oesophagus Achiam, M., Holm, J. & Svendsen, L. B. 6 jan 2014 I : Ugeskrift for læger [online]. 176, 2A Total pancreatectomy with accidential lesion of the left gastric artery, followed by assessement of gastric vitality using laser speckle contrast imaging, a case report Ambrus, R., Storkholm, J. H., Jensen, K. H., Stender, M. T. & Svendsen, L. B I : Research. s. 1:712 Prophylactic total gastrectomy in hereditary diffuse gastric cancer: identification of two novel CDH1 gene mutations-a clinical observational study Bardram, L., Hansen, T. V. O., Gerdes, A-M., Timshel, S., Friis-Hansen, L. & Federspiel, B. 4 jan 2014 I : Familial cancer. 13, s Down-Regulation of mir-129-5p and the let-7 Family in Neuroendocrine Tumors and Metastases Leads to Up- Regulation of Their Targets Egr1, G3bp1, Hmga2 and Bach1 Døssing, K. B. V., Binderup, T., Kaczkowski, B., Jacobsen, A., Rossing, M., Winther, O., Federspiel, B., Knigge, U., Kjær, A. & Friis-Hansen, L I : Genes. 6, 1, s s. Low risk of pelvic sepsis after intersphincteric proctectomy in patients with low rectal cancer Eriksen, M. H., Maina, P. & Jensen, K. H. dec 2014 I : Danish Medical Bulletin (Online). 61, 12, s. A4972 Robotassisteret abdominal cancerkirurgi - fremtiden?: Robot assisted surgery for abdominal cancer is the future? Gögenur, I. & Svendsen, L. B. 2 jun 2014 I : Ugeskrift for læger [online]. 176, 11A, s. V

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