BME Undergraduate Program Handbook



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BME Undergraduate Program Handbook Note: The handbook is updated every year (every semester, if necessary). We recommend that students and faculty always use the latest version of the handbook. (For use in the Fall 2012 Semester) Version F12 1

Highlights of Important Changes 1. Changes from the Spring 2012 Version: New number for EGR 53L is corrected: EGR 103L (not 101L). ECE 110L (27L) replaces BME 253L (153L) for matriculating classes > 2012. Approved Math courses are revised for matriculating classes > 2011. Curricula for the BME majors, matriculating class of 2012, are in Tables 1gh. New section on planning for study abroad has been added (pp.12-13). New Table 6 lists area designations of Special Topics courses. New section listing Student Outcomes and Program Criteria (p. 5). 2. Changes from the Fall 2011 Version: New course numbers are included. Old course numbers are given in parentheses. For example, BME 100L is now listed as BME 260L (100L). Requirements for students considering Medical School are updated (pp. 10-12). BME 255 (155), Safety of Medical Devices, no longer counts as a BME Area Elective (effective Fall 2012). Physiology requirement is now included in Tables 2a-b (BME majors, matriculating class 2010). In previous versions, this requirement was specified only on pp. 6. More course options are added for students with AP credits for Physics 151L (61L) and 152L (62L). ECE 110L (27L) is equivalent to BME 253L (153L) for all BME, BME/ME and BME/CEE majors (effective Fall 2012). A clarification is added for BME/Math majors: students who start BME/Math sequence of mathematics courses must complete it. Version F12 2

Table of Content Introduction... 4 Mission... 4 Program Educational Objectives... 5 Students Outcomes and Program Criteria... 5 Pratt School of Engineering and BME Major Requirements... 5 Two Life Science Courses and Physiology Requirement... 6 Two Chemistry Courses... 6 Two Physics Courses... 6 Five Mathematics Courses... 7 One Statistics Course... 8 Digital Computation and Computer Programming... 8 Five Social Sciences and Humanities (SSH) Courses... 8 One Undergraduate Writing Course... 8 BME Required Courses... 8 BME Electives... 9 Unrestricted Electives... 9 Independent Study and Pratt Fellow Program... 10 Graduation with Distinction... 10 Preparation for Medical School... 10 Double Major, Second Major, Minor, and Certificate Programs... 12 Sample Curricula and AP Credits... 12 Planning for Study Abroad... 12 4 + 1 BSE/MS Program (Five-Year Combined Bachelor/Master Degree Program)... 13 Advising... 13 Information on Internship, Co-Op, Employment, and Graduate School Opportunities... 14 APPENDICES... 16 Tables 1-4: Samples of BME Major and Its Related Double Major Curricula... 16 BME Major (matriculating classes 2008, 2009)... 16 BME Major (matriculating class 2010)... 18 BME Major (matriculating class 2011)... 20 BME Major (matriculating classes 2012)... 22 BME/ECE Double Major (matriculating classes 2010)... 24 BME/ECE Double Major (matriculating classes 2011)... 25 BME/ME Double Major (matriculating classes 2010)... 26 BME/ME Double Major (matriculating classes 2011)... 27 BME/CEE Double Major (matriculating classes 2010)... 28 BME/CEE Double Major (matriculating classes 2011)... 29 Table 5. BME Area Electives Currently Offered... 30 Table 6. Area Designations of BME Special Topics Courses... 31 Table 7. Approved BME Life Science Elective Courses... 32 Table 7a. Approved BME Physiology Courses... 34 Table 8. Approved Biomechanics Elective Courses... 35 Additional Information on Courses... 36 Version F12 3

Introduction This handbook provides an overview of the undergraduate program in Biomedical Engineering (BME) at Duke University. It covers the program mission, educational objectives, major requirements, double major options, course requirements for students planning to apply for medical school, and research opportunities. The undergraduate major in BME at Duke University is one of the first accredited programs in the United States, and is consistently rated as one of the best BME programs in the nation. In addition, BME is the most popular major in the Pratt School of Engineering and one of the most popular undergraduate majors in the University. The student population is diverse both geographically and culturally, and is a cross-section of the very best students in the nation and from around the world. The training in the program emphasizes research and project-based learning which prepares our students with the necessary skills for successful entry into industry and professional schools (e.g., graduate school and medical school). The members of the BME department associated with the undergraduate program are: Director of Undergraduate Studies Professor Wanda Krassowska Neu 1151 FCIEMAS Tel: 660-5105 Email: wanda.neu@duke.edu Associate Director of Undergraduate Studies TBD Staff Assistant for the Undergraduate Program Susan Story 136 Hudson Hall Tel: 660-5133 Email: sshstory@duke.edu Mission The general mission of the Department of Biomedical Engineering, as part of Duke University, is to (i) prepare our students for lives of skilled and ethical service to their communities by creating a free and open learning environment that fosters their intellectual growth, (ii) advance the frontiers of scientific inquiry, and (iii) contribute with distinction to the international community of scholarship. As biomedical engineers, our unique mission is to (a) create enabling technologies for the improvement of human health and health care and (b) create new knowledge at the interface between engineering and biomedical science. We work closely with biologists and clinicians to identify important problems that impact human health and solve them using our technical expertise. We engage motivated and talented students in the classroom, laboratory, and clinic, imparting to them the spirit of our mission as we prepare them for future careers as effective, knowledgeable, and ethical leaders in corporate, professional, and academic communities. Version F12 4

Program Educational Objectives We expect that graduates of our program will: (I) be leaders in biomedical engineering or related areas in industry, academia, and medicine. (II) undergo intellectual growth, and be effective in free and open inquiry. (III) engage in life-long learning and receive advanced degrees or training for professional advancement. (IV) utilize experience integrating mathematics, engineering, life science, and design to address complex problems. (V) understand the social and ethical implications of their work. Students Outcomes and Program Criteria Our students will have the following capabilities upon completion of their degrees: a. an ability to apply knowledge of mathematics, science, and engineering b. an ability to design and conduct experiments, as well as to analyze and interpret data c. an ability to design a system, component, or process to meet desired needs within realistic constraints such as economic, environmental, social, political, ethical, health and safety, manufacturability, and sustainability d. an ability to function on multidisciplinary teams e. an ability to identify, formulate, and solve engineering problems f. an understanding of professional and ethical responsibility g. an ability to communicate effectively h. the broad education necessary to understand the impact of engineering solutions in a global, i. economic, environmental, and societal context j. a recognition of the need for, and an ability to engage in life-long learninga knowledge of contemporary issues k. an ability to use the techniques, skills, and modern engineering tools necessary for engineering practice. In addition, as biomedical engineers, our students will have: 1. understanding of biology and physiology 2. capability to apply advanced mathematics, science, and engineering to solve the problems at the interface of engineering and biology 3. capability to apply statistics to solve the problems at the interface of engineering and biology 4. ability to make measurements on and interpret data from living systems 5. ability to address problems associated with the interaction between living and non-living materials and systems Pratt School of Engineering and BME Major Requirements As a program accredited by the Accreditation Board of Engineering and Technology (ABET), the BME curricula must satisfy minimum requirements in mathematics, sciences, and engineering. In addition, the Pratt School of Engineering has requirements for all engineering students. To meet these constraints, the Department of Biomedical Engineering has developed specific requirements for undergraduate students. Samples of curricula for Version F12 5

students with different BME-related major choices are provided in Tables 1-4. In summary, BME students need to take the following courses. Two Life Science Courses and Physiology Requirement (For matriculating classes < 2010) Biology (25L) D or AP credit in Biology [Biology 20 (19)] is required for all BME single or double majors. The second course can be selected from Table 7. (For matriculating class = 2010) Biology 201L (101L) is required for all BME single or double majors. AP credit cannot be used in lieu of Biology 201L (101L). The second course depends on how the student satisfies the requirement of physiology within BME. Students have three options to fulfill this requirement: 1) Take an approved BME Physiology Elective (Table 7a) as their Life Science elective. 2) Take BME 301L (201L) or BME 307 (207) as one of their Area Core courses. 3) Take BME 244L (144L) as their BME General elective. If options 2 or 3 are chosen, the Life Science elective can be selected from Table 7. (For matriculating class 2011) Biology 201L (101L) and BME 244L (144L), Quantitative Physiology, are required for all BME single or double majors. The Life Science elective course can be selected from Table 7. Two Chemistry Courses (For matriculating classes < 2009) Most students take Chemistry (21L) D and (22L) D. AP credit [Chemistry 21 (19)] is accepted in place of Chemistry (21L). D To fulfill the second chemistry requirement, students can take either Chemistry (22L), D (23L), D or 201DL (151L). (For matriculating classes 2009) Students are required to have Chem 21 (19) (AP=5) or take Chem 101DL (31L) or Chem 110DL (43L).The second course is Chem 210DL (32L) or Chem 201DL (151L). Chemistry options: no AP or AP 4: [Chem 101DL (31L) or Chem 110DL (43L)] and [Chem 210DL (32L) or Chem 201DL (151L)] Chem 21 (19) with AP=5: Chem 210DL (32L) or Chem 201DL (151L) Two Physics Courses The choices are as follows: Physics 151L (61L) + Physics152L (62L) Physics 161L (41L) + Physics 162L (42L): for students transferring from the Trinity College. AP credits are accepted in place of Physics 151L (61L) and 152L (62L): Physics 25 (61) for Physics C Exam on Mechanics and Physics 26 (62) for Physics C Exam on Electricity and D This superscript will indicate courses that are no longer offered. Version F12 6

Magnetism (score 4 or 5). If students use AP credits for both courses, they must take Physics 153L (63L), 264 (143), 361 (181), or 362 (182). Students may not take Physics 151L (61L) at Duke and use AP credit for Physics 152L (Physics 62L). Physics AP options: If no AP credit or AP<4: Physics 151L (61L) and Physics 152L (62L) If you have Physics 25 (61) with AP=4, 5: Physics 152 (62L) If you have Physics 25 (61) and Physics 26 (62) with AP=4, 5: Physics 153L (63L) or 264 (143) or 361 (181) or 362 (182) For premed students who take the Physics 151L (61L) + Physics 152L (62L) sequence: It is highly recommended that you also take Physics 153L (63L) because Physics 151L (61L) and Physics 152L (62L) do not cover all the materials in the MCAT. Five Mathematics Courses All BME single and double majors must take Math 111L (31L), 112L (32L), 212 (103), 216 (107) and 353 (108). AP credit [Math 21 (31)] is accepted in place of Math 111L (31L) and AP credit [Math 22 (32)] is accepted in place of 112L (32L). However, it is recommended that AP credit be used only for Math 111L (31L). Common questions about mathematics placement are answered at the website: http://www.math.duke.edu. Transfer credits are examined on an individual basis. Math options for the first two courses: No AP: Math 111L (31L) and 112L (32L) Math 21 (31) AP: Math 122L (41L) in the Fall or Math 112L (32L) in the Spring Math 21 (31) AP and Math 22 (32) AP: proceed to Math 212 (103) If students are advised by the Math department to skip any courses in the Math sequence listed above, they must replace those courses with additional Math courses approved by the BME DUS. The total number of Math courses taken at Duke plus the number of AP or transfer credits must equal 5. Approved classes include: (For matriculating classes 2010) Math 333 (181), 361S (160S), 451S (132S), 453 (133), 541 (216), CEE 501 (202), CompSci 220 (150) and 334 (140). Math 230 (135) and Math 342 (136) combined can be used in lieu of one Math class and Stat 130 (113). (For matriculating classes 2011) Math 230 (135), 333 (181), 342 (136), 361S (160S), 451S (132S), 453 (133), 541 (216) and Stat 130 (113). BME/Math majors: Students wishing to do a BME/Math double major will need to take Math 111L (31L), 112L (32L), either [212 (103) + 221 (104)] or [221 (104) + 222 (105)], 356 (131), and 453 (133) [221 (104) + 356 (131) substituting for 216 (107), and 453 (133) substituting for 353(108)]. Once students start the BME/Math sequence by taking Math 221 (104), they must complete it. They cannot switch to the regular BME sequence. Version F12 7

One Statistics Course (For matriculating classes 2010) All BME single and double majors must take Stat 130 (113) with the exception of students with second major or a minor in mathematics; these students may take both Math 230 (135) and Math 342 (136) in lieu of Stat 130 (113). (For matriculating classes 2011) Stat 130 (113) is not required for BME majors and BME/ME majors. BME/ECE double majors must take Stat 130 (113) or Math 230 (135) or ECE 555(255); BME/CEE double majors must take Stat 130 (113) or equivalent. Digital Computation and Computer Programming All engineering students must take EGR 103L (53L) to meet this requirement. Students with BME/ECE double major must also take Compsci 201 (100). Five Social Sciences and Humanities (SSH) Courses The specific requirements are as follows: At least one course must be a social science (SS). Other courses must be selected from at least two of the following three areas: arts, literature, and performance (ALP), civilization (CZ), and foreign language (FL). At least two courses must be taken from the same department with one being at 200-level or higher. Skill courses cannot be used to fulfill the SSH requirements. A maximum of two AP credits are accepted in place of the SSH requirements. SSH courses taken in an engineering or science department (e.g., Chemistry) count only if they are cross-listed in an SSH department. One Undergraduate Writing Course Writing 101 (20) is required. BME Required Courses (For matriculating classes 2008-2010) For students in the BME major, the following nine courses are required: EGR 201L (75L), ME 221L (83L), BME 260L (100L), BME 253L (153L), BME 271 (171) or ECE 280L (54L), BME 354L (154L), two BME Area Core classes, and a BME design course. (For matriculating class 2011) For students in the BME major, the following ten courses are required: EGR 201L (75L), ME 221L (83L), BME 244L (144L), BME 260L (100L), BME 253L (153L) or ECE 110L (27L), BME 271 (171) or ECE 280L (54L), BME 354L (154L), two BME Area Core classes, and a BME design course. Version F12 8

(For matriculating classes 2012 and beyond) For students in the BME major, the following ten courses are required: EGR 201L (75L), ME 221L (83L), BME 244L (144L), BME 260L (100L), ECE 110L (27L), BME 271 (171) or ECE 280L (54L), BME 354L (154L), two BME Area Core classes and a BME design course. The two Area Core Classes are chosen from the following four areas (see also Table 5): Area Core Class BB (Biomechanics and Biomaterials) BME 302L (202L) Fund. Biomaterials and Biomechanics EL (Electrobiology) BME 301L (201L) Bioelectricity IM (Imaging and Measurement Systems) BME 303 (233) Modern Diagnostic Imaging Systems MC (Molecular, Cellular and Tissue Eng.) BME 307 (207) Transport Phenom in Biological Systems Important: Two BME Area Core Electives must be taken in the Spring semester of your Junior year. These courses are not offered in the Fall semester so you will not be able to graduate on time if you do not take these courses in this semester. Students studying abroad should plan to go abroad no later than the Fall semester of their Junior year. It will be EXTREMELY difficult to go abroad for Spring semester of your Junior year and still graduate on time. The design course can be chosen from the following list: BME 432L Biomechanics and Vehicle Safety Engineering (typically offered in Fall) BME 436L (236L) Biophotonics Instrumentation (typically offered in Spring) BME 460L (260L) Devices for People with Disabilities (typically offered every term) BME 462L (262L) Design for The Developing World (typically offered every term) BME 464L (264L) Medical Instrument Design (typically offered in Fall) BME Electives Students take elective courses to learn advanced knowledge in specific areas of biomedical engineering. More than thirty BME electives have been developed, but the courses offered in any given semester depend on the availability of faculty. To ensure depth in at least one area of Biomedical Engineering, BME majors must take three classes within the same area: one Area Core class and two Area Elective classes. In addition, BME majors must take two BME General Electives. For double majors, the number of BME Area and General Electives required depends on the major (see Tables 1-4). Table 5 provides the current list of the Area Electives. Table 6 provides area designations of Special Topic courses, BME 290 (165) and 590 (265). BME General Elective can be any BME course for which you have the prerequisites and which is not a required course for your major. Up to two independent study courses can be counted as BME General Electives. Unrestricted Electives At most, two unrestricted elective course credits will be counted. The final number depends on the major choice (see Tables 1-4). Only unrestricted electives can be taken on the Satisfactory/Unsatisfactory basis. Version F12 9

Independent Study and Pratt Fellow Program Independent study is an integral and immensely popular component of the undergraduate education at Duke. Up to two such courses (during Junior and Senior years only) can be counted as BME General Electives [BME 493 (191) and 494 (192)]. The final number depends on the major choice (see Tables 1-4). A research experience can be achieved in one of three ways. Perform directed BME research with a BME faculty member. Take independent study courses with a non-bme faculty member (for instance, a clinician). In such cases, the project must be sponsored by a BME faculty member. The sponsor is responsible for evaluating the quality of the project and student s performance. Some students choose to perform sponsored BME research in the Duke Smart House Program (for details, check the website at http://delta.pratt.duke.edu/). Apply for a Pratt Research Fellow position during your Junior year (to learn more, check the website at http://www.pratt.duke.edu/pratt-research-fellow). Pratt Research Fellows perform research in a BME faculty s lab for three academic semesters plus a full summer term and receive two BME General elective credits [BME 493(191) and 494 (192)]. Graduation with Distinction Graduation with Distinction Award is presented to the Pratt students who, in the opinion of the BME Department and a committee of the faculty, have demonstrated exceptional achievement in the areas of their special interest by conducting independent research and presenting the research project with a distinguished piece of writing and/or a poster presentation. BME students who have final grade point average of 3.5 or higher and have taken BME 493 (191) through either an independent study or the Pratt Research Fellow Program are eligible to apply for the Award (for details, email the BME DUS). All students who graduate in December and want to apply for Graduation with Distinction should present the research project in the symposium held in April in the year prior to graduation. Preparation for Medical School Students planning to attend medical and dental schools should consult with their advisor and the Office of Health Professions Advising (HPA) about course planning. HPA is located at 011 Allen Building (the website is http://prehealth.duke.edu). The Office provides advice to students planning careers in health professions and also information on the application process, degree requirements, research and volunteer opportunities. While the following information is thought to be correct, students should use the Health Professions Advising at Duke as their primary source for Medical School requirements and advice. Version F12 10

Medical and dental schools in the US require students to take the following courses: Subject Duke Courses BME curriculum Chemistry Chem 101DL (31L) or 110DL (43L) or 21 (19-AP) required 4 semesters Chem 201DL (151L) required with lab Chem 202L (152L) free elective Chem 210DL or/and Biochem 301 (227) 1 free elective/extra class/ls Biology Molecular: Bio 201L (101L) required 2 semesters Genetics: Bio 202L (102L) LS elective with lab Physiology: BME 244L (144L) 2 required/ge/extra class Physics Phys 151L (61L) or 25 (61-AP) required 2 semesters Phys 152L (62L) or 26 (62-AP) required with lab Phys 153L (63L) 3 extra class English Writing 101 (20) required 2 semesters English/Lit course or English AP credit SSH elective Behav Sci Psy 101 (11) or Soc 110 (10) or Soc 111 (11) SSH elective Statistics Stat 130 (113) 4 required/extra class 1 Biochemistry will be included in MCAT exams starting in 2015. It should be taken in the Fall of the Junior year or in the Summer before the Junior year (it is not offered in the Spring). For students taking MCAT exams in 2015 and beyond, Biochem 301 (227) replaces Chem 210DL (32L). For current students who take Chem 210DL (32L), Biochem 301 (227) is strongly recommended as an extra class or an LS elective. 2 BME 244L (144L) is required for matriculating classes of 2011 and above. Matriculating classes <2011 can take BME 244L (144L) as a BME general elective; or Bio 221 (117), Bio 329 (151), Cellbio 503 (203) or Evanth 330L (155L) as an extra class. 3 Phys 153 (63L) is strongly recommended because Phys 151L (61L) and 152L (62L) do not cover all the material on MCAT exams. 4 Stat 130 (113) is required for matriculating classes <2011. Matriculating classes 2011 and above will have statistics incorporated into their BME courses; Stat 130 (113) is recommended as an extra class. Note: BME 244L (144L) is accepted as a biology course with a lab by most medical schools. The lab portion of BME 301L (201L) is accepted as one of the biology lab requirements by most medical schools. Note however that the lecture portion of BME 301L (201L) does not count as a biology course. As seen in the above table, many courses satisfy the requirements for both the BME major and the entrance to medical and dental schools. Examples of schedules for premed and BME are shown in Tables 1b,d,f,h. Students should complete all of their MCAT-related courses Version F12 11

prior to the summer between their Junior and Senior year. This allows the MCAT to be taken in that summer, which permits more preparation time.. Double Major, Second Major, Minor, and Certificate Programs To obtain depth in specific BME areas, students can declare a double major within the Pratt School of Engineering. For these students, the required courses are listed in Tables 2-4. Opportunities also exist for students with AP credits to combine the BME major with a second major, minor, or certificate from the Trinity College. (A certificate is similar to a minor but offered for interdisciplinary study.) To do so, the students must meet the same requirements as those for BME single major plus the specific requirements from other departments/programs outlined in the Bulletin of Undergraduate Instruction (http://registrar.duke.edu/bulletins/undergraduate/). The additional requirements usually consist of 10 courses for a second major, 5 courses for a minor, and 6 courses for a certificate. Some of these courses can be double-counted towards both the BME degree and the second major, minor or certificate in the Trinity College. For example, two courses required for the second major in economics may be counted as two of the five SSH courses required for the BME degree. To reduce the work load for obtaining the second major, minor, or certificate in the Trinity College during the regular academic semesters, students can either take the required Trinity courses as unrestricted electives in the BME curriculum or take them in the summer. Sample Curricula and AP Credits Tables 1-4 provide samples of curricula for BME majors, BME majors considering Medical School, and double majors. Most common changes to these curricula are as follows: Students with AP credits for Math 21 (31) should take Math 122L (41L) in the Fall and Math 212 (103) in the Spring of their Freshman year. This will eliminate a 5-course semester in the Fall of Sophomore year. Students with AP credits for Physics 25 (61) should take Chem 210DL (32L) or Chem 201DL (151L) in the Spring of their Freshman year. This will eliminate a 5-course semester in the Spring of Sophomore year. Students with AP credits for Math 21 (31) and Physics 25 (61) who are considering Medical School should move Math 122L (41L) and 212 (103) as described above, take Chem 201DL (151L) in the Spring of their Freshman year, and Chem 202L (152L) in the Fall of their Sophomore year. This will eliminate 5-course semesters in the Sophomore year. Students with AP credits for Chem 21 (19) who do not take Chem 101DL (31L) or 110DL (43L) should take Biology 201L (101L) in the Fall of their Freshman year and Chem 210DL (32L) or Chem 201DL (Chem 151L) in the Spring of their Freshman year. Planning for Study Abroad Students interested in participating in the Global Education program need to develop an academic plan with their advisors several semesters in advance. This plan includes the courses to be taken in foreign countries and the remaining courses to be taken at Duke before and after the semester abroad. Students intending to study abroad should plan to travel in the Fall semester of their Junior year. In the semester prior to study abroad, students submit requests Version F12 12

to the BME DUS. The process for approval of courses in the study abroad program is the same as that used for all transfer courses. For details, see http://studyabroad.duke.edu. Currently, very few of the required BME courses are offered abroad. Typically, students receive credit for BME 271 (171), Social Studies and Humanities electives, Life Science elective, and/or BME General Elective. A few places also offer a course equivalent to ME 221L (83L). Therefore, the following courses should be taken before the semester abroad: BME 260L (100L); it is a prerequisite for BME 307, an Area Core course for Molecular, Cellular, and Tissue Engineering. ME 227L (83L) unless it is offered abroad. This course is a prerequisite for BME 302L (202L), an Area Core course for Biomechanics and Biomaterials. Note that EGR 201L (75L) is a prerequisite for ME 221L (83L), so it should be taken in the Fall of your Sophomore year. Math 353 (108), which is also a prerequisite for BME 302L (202L). BME 271 (171) if not taken abroad. It is a prerequisite for BME 303 (233), an Area Core course for Imaging and Measurement Systems. 4 + 1 BSE/MS Program (Five-Year Combined Bachelor/Master Degree Program) The program offers a five-year combined Bachelor of Science and Master of Science degree in biomedical engineering. This is a great opportunity for students who want to broaden their undergraduate research experience or to obtain advanced training in biomedical engineering. In addition to completing both degrees in five years, students do not pay the graduate tuition for their graduate courses taken in the senior year (for more information, see http://www.pratt.duke.edu/4+1-bse-ms). The degree requires that the students fulfill the standard degree requirements for Bachelor of Science plus an additional 30 units of upper level courses suitable for a graduate degree. (In the Graduate School, a 3-hour/week course is counted as 3 units.) Up to 15 graduate course units (5 graduate courses) out of the 30 units can be taken in the senior year, provided that these courses are not used to fulfill the Bachelor degree requirements and they are not Independent Study courses. If you complete two or more courses toward your MS degree before completing your senior year, you can easily complete the remaining graduate courses in one year beyond your BSE. More information can be found here at http://www.pratt.duke.edu/4+1-bse-ms. To complete both Bachelors and Masters degrees in five years: Develop course plans for your senior year and for one graduate year with your academic advisor and obtain Director of Graduate Studies (DGS) approval. Take the GRE exam in the Fall of your Senior year. Apply for admission to Duke's Graduate School during the Fall of your Senior year. Apply online here (http://gradschool.duke.edu/admissions/index.php). Advising Assignment of BME advisors: Due to the high student/faculty ratio in the BME program, the BME faculty do not usually advise Freshmen. A BME advisor is assigned after the student declares a BME or BME/double major. Students can declare majors or change them at any Version F12 13

time after their Freshman year. To do this, the students complete an online form (http://www.pratt.duke.edu/forms/declaration-of-major). The assignment of faculty advisors is based upon the major interests (e.g., BME/ECE double major) expressed by the students and the need to balance the number of advisees per faculty. Currently, each BME faculty member advises an average of twenty students. A student s advisor may vary from semester to semester for various reasons (e.g., faculty on sabbatical and the arrival of new faculty). Thus, students need to check their academic information every semester before making an appointment. The address of BME website for making an online appointment is http://advising.pratt.duke.edu/ Freshman advising: In order to provide program information to Freshmen interested in BME, all students are invited to an orientation presented by the BME Director/Associate Director of Undergraduate Studies (DUS) at the end of August, prior to the start of classes. The presentation covers the degree requirements and commonly asked questions. Individual advising sessions can be arranged if requested. In October and March/April, during the preregistration periods, the BME DUS and/or Associate DUS will also hold open consultation sessions for the first year students who have BME-related questions. To assist undecided students choosing a major in engineering, an elective course, EGR 90L (10), Introduction to Engineering, is offered to first year students in the Fall term. This course surveys the fields of engineering offered by the Pratt School of Engineering, including two presentations from each department given by senior students, faculty, industrial leaders, and/or recent alumni. Pre-registration advising of BME students: Students meet with their advisors during the preregistration period in March/April for the Fall semester and in October for the Spring semester. The advisor reviews the student's academic report, discusses with the student the courses that he or she will take in the following semester. The advisor maintains a record of the student s current academic plan. The student is responsible for informing the advisor of any changes in the plan. Career advising: Students can discuss their career plans with their advisors. In addition, advisors can help students to identify specific sequences of courses or double major options that are most appropriate for them. Information on Internship, Co-Op, Employment, and Graduate School Opportunities Information on internship, co-op, and employment opportunities is posted on the website of the Duke University Career Center: http://www.studentaffairs.duke.edu/career. In addition to maintaining the websites mentioned above, the Career Center organizes various career-related activities. These include (a) career advice sessions, (b) industrial interview events, (c) graduate school recruiting events, and (d) workshops and seminars on internship, co-op, and employment that are specific for engineering or BME students. The workshops and seminars are announced via emails and posted on the TV monitors in the engineering buildings. The Career Center is located in Smith Warehouse at 114 S. Buchanan Blvd, Bay 5. Version F12 14

In addition to the Career Center, Russell Holloway (russell.holloway@duke.edu), Associate Dean of Corporate and Industry Relations in the Pratt School of Engineering, helps Pratt students connect with corporations for internship opportunities. For more information, see http://www.pratt.duke.edu/undergraduate-internship. Information on internships, co-ops, employment, and graduate school opportunities is sent directly to the BME faculty or the department. When this happens, the information will be distributed to BME students via emails or posted on the bulletin board outside the BME departmental office. Version F12 15

APPENDICES Tables 1-4: Samples of BME Major and Its Related Double Major Curricula Table 1a BME Major (matriculating classes 2008, 2009) Freshman Year Chem (21L) D or 101DL (31L)Core Concepts in Chemistry Chem (22L) D or 210DL (32L)Applied Chem Princ or 201DL (151L) Organic Chemistry EGR 103L (53L) Computational Methods in Engineering Math 112L (32L) Introductory Calculus II Math 111L (31L) Introductory Calculus I Physics 151L (61L) Introductory Mechanics 1 Writing 101 (20) Sophomore Year EGR 201L (75L) Mechanics of Solids or BME (110L) D ME 221L (83L) or BME(83L) D Intro to Biomaterials Bio (25L) D Principles of Biology BME 260L (100L) Modeling Cellul and Molecul Systems Math 212 (103) Multivariable Calculus 2 BME 253L (153L) Biomed Electronics and Measurem I Physics 152L (62L) Intro Electric, Magnet, Optics 1 Math 216 (107) Linear Algebra and Differential Eqn 2 Junior Year BME 271 (171) Signals and Systems or ECE 280L(54L) BME 354L (154L) Biomed Electronics & Measurem II Math 353 (108) Ordinary and Partial Differential Eqn 2 BME Area Core Class I 3 Life Science Elective BME Area Core Class II 3 Stat 130 (113) Probability and Statistics for Engineers Senior Year BME Design 4 BME Area Elective 5 BME Area Elective 5 BME General Elective 6 BME General Elective 6 Elective Elective 1. See also the Physics requirements on pp. 6-7. 2. Students with BME/Math double-major need to take Math 221/212 or 222/356/453 (104/103 or 105/131/133) in place of Math 212/216/353 (103/107/108). 3. Selected from the four Area Core classes listed in Table 5. 4. Selected from the following list: BME 432L Biomechanics and Vehicle Safety Engineering BME 436L (236L) Biophotonics Instrumentation BME 460L (260L) Devices for People with Disabilities BME 462L (262L) Design for The Developing World BME 464L (264L) Medical Instrument Design 5. Both BME Area Electives (Tables 5-6) must be from the same Area of Focus. 6. BME General Electives can be at any level. Version F12 16

Table 1b BME Major (matriculating classes 2008, 2009) Course plan for students considering medical school Freshman Year Chemistry (21L) D or 101DL (31L) Core Concepts in Chemistry Chemistry (22L) D or 210DL (32L) Mod Apps Chem Principles EGR 103L (53L ) Computational Methods in Engineering Math 112L (32L) Introductory Calculus II Math 111L (31L) Introductory Calculus I Physics 151L (61L) Introductory Mechanics 1 Writing 101 (20) Sophomore Year EGR 201L (75L) Mechanics of Solids or BME (110L) D BME 253L (153L) Biomed Electronics and Measurem I Math 212 (103) Multivariable Calculus 2 Biology (25L) D or 201L (101L) Molecular Biology Physics 152L (62L) Intro Electric, Magnet, Optics 1 Math 216 (107) Linear Algebra and Differential Eqn 2 Chemistry 201DL (151L) Organic Chemistry I Chemistry 202L (152L) Organic Chemistry II Junior Year ME 221L (83L) or BME (83L) D Intro to Biomaterials BME 354L (154L) Biomed Electronics and Measurem II BME 260L (100L) Modeling Cellul and Molecul Systems BME Area Core Class I 3 BME 271 (171) Signals and Systems or ECE 280L(54L) BME Area Core Class II 3 Math 353 (108) Ordinary and Partial Differential Eqn 2 Stat 130 (113) Probability and Statistics for Engineers Senior Year BME Design 4 BME Area Elective 5 BME Area Elective 5 BME General Elective 6 Life Science Elective BME General Elective 6 1. See also the Physics requirements on pp. 6-7. 2. Students with BME/Math double-major need to take Math 221/212 or 222/356/453 (104/103 or 105/131/133) in place of Math 212/216/353 (103/107/108). 3. Selected from the four Area Core classes listed in Table 5. 4. Selected from the following list: BME 432L Biomechanics and Vehicle Safety Engineering BME 436L (236L) Biophotonics Instrumentation BME 460L (260L) Devices for People with Disabilities BME 462L (262L) Design for the Developing World BME 464L (264L) Medical Instrument Design 5. Both BME Area Electives (Tables 5-6) must be from the same Area of Focus. 6. BME General Electives can be at any level. Version F12 17

Chem 101DL (31L) Core Concepts in Chemistry Table 1c BME Major (matriculating class 2010) Freshman Year Chem 210DL (32L) Mod Apps Chem Principles or Chem 201DL (151L) Organic Chemistry Math 112L (32L) Introductory Calculus II EGR 103L (53L) Computational Methods in Engineering Math 111L (31L) Introductory Calculus I Physics 151L (61L) Introductory Mechanics 1 Writing 101 (20) Sophomore Year EGR 201L (75L) Mechanics of Solids BME 260L (100L) Modeling Cellul and Molecul Systems Biology 201L (101L) Molecular Biology BME 253L (153L) Biomedic Electronics and Measurem I or ECE 110L (27L) Fund Electr and Comput Eng Math 212 (Math 103) Multivariable Calculus 2 ME 221L (ME 83L) Structure and Properties of Solids Physics 152L (62L) Intro Electric, Magnet, Optics 1 Math 216 (107) Linear Algebra and Differential Eqn 2 Junior Year BME 271 (171) Signals and Systems or ECE 280L(54L) BME 354L (154L) Biomed Electronics and Measurem II Math 353 (108) Ordinary and Partial Differential Eqn 2 BME Area Core Class I 3 Physiology or Life Science Elective BME Area Core Class II 3 Stat 130 (113) Probability and Statistics for Engineers Senior Year BME Design 4 BME Area Elective 5 BME Area Elective 5 BME General Elective 6 BME General Elective 6 Elective Elective 1. See also the Physics requirements on pp. 6-7. 2. Students with BME/Math double-major need to take Math 221/212 or 222/356/453 (104/103 or 105/131/133) in place of Math 212/216/353 (103/107/108). 3. Selected from the four Area Core classes listed in Table 5. 4. Selected from the following list: BME 432L Biomechanics and Vehicle Safety Engineering BME 426L (236L) Biophotonics Instrumentation BME 460L (260L) Devices for People with Disabilities BME 462L (262L) Design for the Developing World BME 464L (264L) Medical Instrument Design 5. Both BME Area Electives (Tables 5-6) must be from the same Area of Focus. 6. BME General Electives can be at any level. Version F12 18

Table 1d BME Major (matriculating class 2010) Course plan for students considering medical school Freshman Year Chem 101DL (31L) Core Concepts in Chemistry Chem 210DL (32L) Mod Apps Chem Principles EGR 103L (53L) Computational Methods in Engineering Math 112L (32L) Introductory Calculus II Math 111L (Math 31L) Introductory Calculus I Physics 151L (61L) Introductory Mechanics 1 Writing 101 (20) Sophomore Year EGR 201L (75L) Mechanics of Solids BME 253L (153L) Biomed Electronics and Measurem I or ECE 110L (27L) Fund Electr and Comput Eng Math 212 (103) Multivariable Calculus 2 Biology 201L (Biology 101L) Molecular Biology Physics 152L (62L) Intro Electric, Magnet, Optics 1 Math 216 (107) Linear Algebra and Differential Eqn 2 Chem 201DL (151L) Organic Chemistry Chem 202L (152L) Organic Chemistry Junior Year BME 260L (100L) Modeling Cellul and Molecul Systems BME 354L (154L) Biomed Electronics and Measurem II BME 271 (171) Signals and Systems or ECE 280L (54L) BME Area Core Class I 3 [BME 301L (201L)] ME 221L (83L) Structure and Properties of Solids BME Area Core Class II 3 Math 353 (108) Ordinary and Partial Differential Eqn 2 Stat 130 (113) Probability and Statistics for Engineers Senior Year BME Design 4 BME Area Elective 5 BME Area Elective 5 BME General Elective 6 Physiology or Life Science Elective BME General Elective 6 1. See also the Physics requirements on pp. 6-7. 2. Students with BME/Math double-major need to take Math 221/212 or 222/356/453 (104/103 or 105/131/133) in place of Math 212/216/353 (Math 103/107/108). 3. Selected from the four Area Core classes listed in Table 5. 4. Selected from the following list: BME 432L Biomechanics and Vehicle Safety Engineering BME 436L (236L) Biophotonics Instrumentation BME 460L (260L) Devices for People with Disabilities BME 462L (262L) Design for The Developing World BME 462L (264L) Medical Instrument Design 5. Both BME Area Electives (Tables 5-6) must be from the same Area of Focus. 6. BME General Electives can be at any level. Version F12 19

Chem 101DL (31L) Core Concepts in Chemistry Table 1e BME Major (matriculating class 2011) EGR 103L (53L) Computational Methods in Engineering Math 111L (31L) Introductory Calculus I Writing 101 (20) Freshman Year Sophomore Year Bio 201L (101L) Molecular Biology [alt: Chem 210DL (32L) or Chem 201DL (151L)] Math 112L (Math 32L) Introductory Calculus II Physics 151L (61L) Introductory Mechanics BME 244L (144L) Quantitative Physiology [alt: Bio 201L (101L)] BME 253L (153L) Biomed Electronic Measurem I or ECE110L (27L) Fund Electr and Comput Eng EGR 201L (75L) Mechanics of Solids Chem 210DL (32L) Mod Apps Chem Principles or Chem 201DL (151L) Organic Chem [(alt: BME 244L (144L)] Math 212 (103) Multivariable Calculus 2 Math 216 (107) Linear Algebra and Differential Eqn 2 Physics 152L (62L) Intro Electric, Magnet, Optics Life Science Elective Junior Year BME 260L (100L) Modeling Cellul and Molecul Systems BME 354L (154L) Biomed Electronic Measurem II BME 271 (171) Signals & Systems or ECE 280L (54L) BME Area Core Class I 3 ME 221L (83L) Structure and Properties of Solids BME Area Core Class II 3 Math 353 (108) Ordinary and Partial Diff Equations 2 Senior Year BME Design 4 BME Area Elective 5 BME Area Elective 5 BME General Elective 6 BME General Elective 6 Elective Elective 1. See also the Physics requirements on pp 6-7. 2. Students with BME/Math double-major need to take Math 221/212 or 222/356/453 (104/103 or 105/131/133) in place of Math 212/216/353 (103/107/108). 3. Selected from the four Area Core classes listed in Table 5. 4. Selected from the following list: BME 432L Biomechanics and Vehicle Safety Engineering BME 436L (236L) Biophotonics Instrumentation BME 460L (260L) Devices for People with Disabilities BME 426L (262L) Design for the Developing World BME 464L (264L) Medical Instrument Design 5. Both BME Area Electives (Tables 5-6) must be from the same Area of Focus. 6. BME General Electives can be at any level. Version F12 20

Table 1f BME Major (matriculating class 2011) Course plan for students considering medical school Freshman Year Chem 101DL (31L) Core Concepts in Chemistry Chem 201DL (151L) Organic Chemistry EGR 103L (53L) Computational Methods in Engineering Biology 201L (101L) Molecular Biology [alt: ] Math 111L (31L) Introductory Calculus I Math 112L (32L) Introductory Calculus II Writing 101 (20) Academic Writing Physics 151L (61L) Introductory Mechanics 1 Sophomore Year BME 244L (144L) Quantitative Physiology [alt: Bio 201L (101L)] BME 253L (153L) Biomed Electronic Measurem I or ECE110L (27L) Fund Electr and Comput Eng EGR 201L (75L) Mechanics of Solids Chem 210DL (32L) Modern Appl Chem Principles Chem 202L (152L) Organic Chemistry Math 216 (107) Linear Algebra and Differential Eqn 2 Math 212 (103) Multivariable Calculus 2 Life Science Elective Physics 152L (62L) Intro Electricity, Magnetism and Optics 1 [alt: BME 244L (144L)] Junior Year BME 260L (100L) Modeling Cellul and Molecul Systems BME 354L (154L) Biomed Electronic Measurem II BME 271 (171) Signals & Systems or ECE 280L (54L) BME Area Core Class I 3 ME 221L (83L) Structure and Properties of Solids BME Area Core Class II 3 Math 353 (108) Ordinary and Partial Differential Eqn 2 Senior Year BME Design 4 BME Area Elective 5 BME Area Elective 5 BME General Elective 6 BME General Elective 6 1. See also the Physics requirements on pp. 6-7. 2. Students with BME/Math double-major need to take Math 221/212 or 222/356/453 (104/103 or 105/131/133) in place of Math 212/216/353 (Math 103/107/108). 3. Selected from the four Area Core classes listed in Table 5. 4. Selected from the following list: BME 432L Biomechanics of Vehicle Safety Engineering BME 436L (236L) Biophotonics Instrumentation BME 460L (260L) Devices for People with Disabilities BME 462L (262L) Design for the Developing World BME 464L (264L) Medical Instrument Design 5. Both BME Area Electives (Tables 5-6) must be from the same Area of Focus. 6. BME General Electives can be at any level. Version F12 21

Table 1g BME Major (matriculating classes 2012) Freshman Year Chem 101DL (31L) Core Concepts in Chemistry Biology 201L (101L) Molecular Biology EGR 103L (53L) Computational Methods in Engineering Math 112L (32L) Introductory Calculus II Math 111L (31L) Introductory Calculus I Physics 151L (61L) Introductory Mechanics 1 Writing 101 (20) Academic Writing Sophomore Year BME 244L (144L) Quantitative Physiology EGR 201L (75L) Mechanics of Solids ECE 110L (27L) Fund Electr and Comput Eng Chem 210DL (32L) Mod Apps Chem Principles or Chem 201DL (151L) Organic Chem Math 212 (103) Multivariable Calculus 2 Math 216 (107) Linear Algebra and Differential Eqn 2 Physics 152L (62L) Intro Electric, Magnetism and Optics 1 Life Science Elective Junior Year BME 260L (100L) Modeling Cellul and Molecul Systems BME 354L (154L) Biomed Electronic Measurem II BME 271 (171) Signals & Systems or ECE 280L (54L) BME Area Core Class I 3 ME 221L (83L) Structure and Properties of Solids BME Area Core Class II 3 Math 353 (108) Ordinary and Partial Diff Equations 2 Senior Year BME Design 4 BME Area Elective 5 BME Area Elective 5 BME General Elective 6 BME General Elective 6 Elective Elective 1. See also the Physics requirements on pp. 6-7. 2. Students with BME/Math double-major need to take Math 221/212 or 222/356/453 (104/103 or 105/131/133) in place of Math 212/216/353 (Math 103/107/108). 3. Selected from the four Area Core classes listed in Table 5. 4. Selected from the following list: BME 432L Biomechanics of Vehicle Safety Engineering BME 436L (236L) Biophotonics Instrumentation BME 460L (260L) Devices for People with Disabilities BME 462L (262L) Design for the Developing World BME 464L (264L) Medical Instrument Design 5. Both BME Area Electives (Tables 5-6) must be from the same Area of Focus. 6. BME General Electives can be at any level. Version F12 22

Table 1h BME Major (matriculating classes 2012) Course plan for students considering medical school Chem 101DL (31L) Core Concepts in Chemistry EGR 103L (53L) Computational Methods in Engineering Math 111L (31L) Introductory Calculus I Writing 101 (20) Academic Writing Freshman Year Sophomore Year Biology 201L (101L) Molecular Biology Math 112L (32L) Introductory Calculus II Physics 151L (61L) Introductory Mechanics BME 244L (144L) Quantitative Physiology BME 260L (100L) Modeling Cellul and Molecul Systems ECE 110L (27L) Fund Electr and Comput Eng EGR 201L (75L) Mechanics of Solids Chem 201DL (151L) Organic Chemistry 1 Chem 202L (152L) Organic Chemistry 1 Math 212 (103) Multivariable Calculus 2 Math 216 (107) Linear Algebra and Differential Eqn 2 Physics 152L (62L) Intro Electricity, Magnetism and Life Science Elective Optics 1 Junior Year BME 271 (171) Signals & Systems or ECE 280L (54L) BME 354L (154L) Biomed Electronic Measurem II ME 221L (83L) Structure and Properties of Solids BME Area Core Class I 3 Math 353 (108) Ordinary and Partial Differential Eqn 2 BME Area Core Class II 3 Biochem 301 (227) 1 Intro Biochemistry I Senior Year BME Design 4 BME Area Elective 5 BME Area Elective 5 BME General Elective 6 BME General Elective 6 1. See also the Physics requirements on pp. 6-7; HPA recommends taking Chem 201DL (151L) and Chem 202L (152L) in the summer after Freshman year, and Biochem 301 (227) in the summer after Sophomore year. 2. Students with BME/Math double-major need to take Math 221/212 or 222/356/453 (104/103 or 105/131/133) in place of Math 212/216/353 (Math 103/107/108). 3. Selected from the four Area Core classes listed in Table 5. 4. Selected from the following list: BME 432L Biomechanics of Vehicle Safety Engineering BME 436L (236L) Biophotonics Instrumentation BME 460L (260L) Devices for People with Disabilities BME 462L (262L) Design for the Developing World BME 464L (264L) Medical Instrument Design 5. Both BME Area Electives (Tables 5-6) must be from the same Area of Focus. 6. BME General Electives can be at any level. Version F12 23

Table 2a BME/ECE Double Major (matriculating classes 2010) Freshman Year Chem 101DL (31L) Core Concepts in Chemistry Chem 210DL (32L) Mod Apps Chem Principles or Chem 201DL (151L) Organic Chemistry Math 111L (31L) Introductory Calculus I Math 112L (32L) Introductory Calculus II EGR 103L (53L) Computational Methods in Engineering Physics 151L (61L) Introductory Mechanics Writing 101 (20)/ Social Sci or Humanities Elective 1 Social Sci or Humanities Elective 1/Writing 101 (20) Biology 201L (101L) Molecular Biology Math 212 (103)Multivariable Calculus Physics 152L (62L) Electric, Magnet, Optics ECE 110L (27L) Fundamentals of ECE Compsci 201 (100) Program Design and Analysis Sophomore Year Junior Year BME 260L (100L) Modeling Cellul and Molecul Systems EGR 201L (75L) Mechanics of Solids Math 216 (107) Linear Algebra and Differential Eqn ECE 230L (51L) Microelectronic Devices & Circuits ECE 280L(54L) Intro to Signals and Systems ME 221L (83L) Structure and Properties of Solids BME 354L (154L) Biomed Electronics and Measurem II Math 353 (108) Ordinary and Partial Diff. Equations BME 301L (201L) Bioelectricity or BME 303 (233) Modern Diagnostic Imaging Systems 2 ECE 250L (52L) Intro to Digital Systems ECE Concentration Elective 1 1 ECE 270L (53L) Electromagnetic Fields Stat 130 (113) Probability and Statistics 2 3 Senior Year BME design: BME 436L (236L)or464L (264L) BME General Elective BME Area Elective 2 Physiology or Life Science Elective 3 ECE Concentration Elective 2 1 ECE Elective Science or Humanities Elective 4 5 1. At least two ECE Concentration Electives must be from the same Concentration Area 2. If BME 301L (201L) is taken the Area Elective must be from the Bioelectricity Area If BME 303 (233) is taken the Area Elective must be from the Imaging and Sensors Area 3. If BME 303 (233) is taken, choose from approved list of Physiology Electives (Table 7a) If BME 301L (201L) is taken, choose from the approved list of Life Science Electives (Table 7) Version F12 24